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Search of human proteins with 120587025
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo
sapiens]
(2161 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 4440 0.0
gi|226817313 SH3 and multiple ankyrin repeat domains 2 isoform 1... 1258 0.0
gi|122937241 SH3 and multiple ankyrin repeat domains 3 [Homo sap... 900 0.0
gi|169203021 PREDICTED: similar to Shank2E [Homo sapiens] 472 e-132
gi|19743796 SH3 and multiple ankyrin repeat domains 2 isoform 2 ... 231 4e-60
gi|163965366 nascent polypeptide-associated complex alpha subuni... 149 2e-35
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 143 2e-33
gi|153792074 proline rich 12 [Homo sapiens] 142 3e-33
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 129 4e-29
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 126 2e-28
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 125 6e-28
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 121 8e-27
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 120 1e-26
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 116 2e-25
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 116 2e-25
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 110 1e-23
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 110 1e-23
gi|160707881 formin 2 [Homo sapiens] 107 1e-22
gi|30425444 ankyrin repeat and kinase domain containing 1 [Homo ... 101 9e-21
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 97 1e-19
gi|47132519 Ras association and pleckstrin homology domains 1 is... 97 2e-19
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 96 4e-19
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 96 5e-19
gi|110832843 TBP-associated factor 4 [Homo sapiens] 95 6e-19
gi|68131557 ankyrin repeat domain 28 [Homo sapiens] 94 1e-18
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 94 1e-18
gi|188595682 ankyrin 2 isoform 3 [Homo sapiens] 94 2e-18
gi|52426737 ankyrin 2 isoform 2 [Homo sapiens] 94 2e-18
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] 94 2e-18
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens] 94 2e-18
>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
Length = 2161
Score = 4440 bits (11515), Expect = 0.0
Identities = 2161/2161 (100%), Positives = 2161/2161 (100%)
Query: 1 MTHSPATSEDEERHSASECPEGGSESDSSPDGPGRGPRGTRGQGSGAPGSLASVRGLQGR 60
MTHSPATSEDEERHSASECPEGGSESDSSPDGPGRGPRGTRGQGSGAPGSLASVRGLQGR
Sbjct: 1 MTHSPATSEDEERHSASECPEGGSESDSSPDGPGRGPRGTRGQGSGAPGSLASVRGLQGR 60
Query: 61 SMSVPDDAHFSMMVFRIGIPDLHQTKCLRFNPDATIWTAKQQVLCALSESLQDVLNYGLF 120
SMSVPDDAHFSMMVFRIGIPDLHQTKCLRFNPDATIWTAKQQVLCALSESLQDVLNYGLF
Sbjct: 61 SMSVPDDAHFSMMVFRIGIPDLHQTKCLRFNPDATIWTAKQQVLCALSESLQDVLNYGLF 120
Query: 121 QPATSGRDANFLEEERLLREYPQSFEKGVPYLEFRYKTRVYKQTNLDEKQLAKLHTKTGL 180
QPATSGRDANFLEEERLLREYPQSFEKGVPYLEFRYKTRVYKQTNLDEKQLAKLHTKTGL
Sbjct: 121 QPATSGRDANFLEEERLLREYPQSFEKGVPYLEFRYKTRVYKQTNLDEKQLAKLHTKTGL 180
Query: 181 KKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHI 240
KKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHI
Sbjct: 181 KKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHI 240
Query: 241 DFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELL 300
DFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELL
Sbjct: 241 DFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELL 300
Query: 301 LFNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKE 360
LFNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKE
Sbjct: 301 LFNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKE 360
Query: 361 TCARILLYRGADKDVKNNNGQTPFQVAVIAGNFELGELIRNHREQDVVPFQESPKYAARR 420
TCARILLYRGADKDVKNNNGQTPFQVAVIAGNFELGELIRNHREQDVVPFQESPKYAARR
Sbjct: 361 TCARILLYRGADKDVKNNNGQTPFQVAVIAGNFELGELIRNHREQDVVPFQESPKYAARR 420
Query: 421 RGPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQSQPSAPTTK 480
RGPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQSQPSAPTTK
Sbjct: 421 RGPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQSQPSAPTTK 480
Query: 481 LSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPREGPAGGTGGSGGPGGS 540
LSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPREGPAGGTGGSGGPGGS
Sbjct: 481 LSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPREGPAGGTGGSGGPGGS 540
Query: 541 LGSRGRRRKLYSAVPGRSFMAVKSYQAQAEGEISLSKGEKIKVLSIGEGGFWEGQVKGRV 600
LGSRGRRRKLYSAVPGRSFMAVKSYQAQAEGEISLSKGEKIKVLSIGEGGFWEGQVKGRV
Sbjct: 541 LGSRGRRRKLYSAVPGRSFMAVKSYQAQAEGEISLSKGEKIKVLSIGEGGFWEGQVKGRV 600
Query: 601 GWFPSDCLEEVANRSQESKQESRSDKAKRLFRHYTVGSYDSFDAPSLMDGIGPGSDYIIK 660
GWFPSDCLEEVANRSQESKQESRSDKAKRLFRHYTVGSYDSFDAPSLMDGIGPGSDYIIK
Sbjct: 601 GWFPSDCLEEVANRSQESKQESRSDKAKRLFRHYTVGSYDSFDAPSLMDGIGPGSDYIIK 660
Query: 661 EKTVLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGD 720
EKTVLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGD
Sbjct: 661 EKTVLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGD 720
Query: 721 FLIEVNGQNVVKVGHRQVVNMIRQGGNTLMVKVVMVTRHPDMDEAVHKKAPQQAKRLPPP 780
FLIEVNGQNVVKVGHRQVVNMIRQGGNTLMVKVVMVTRHPDMDEAVHKKAPQQAKRLPPP
Sbjct: 721 FLIEVNGQNVVKVGHRQVVNMIRQGGNTLMVKVVMVTRHPDMDEAVHKKAPQQAKRLPPP 780
Query: 781 TISLRSKSMTSELEEMEYEQQPAPVPSMEKKRTVYQMALNKLDEILAAAQQTISASESPG 840
TISLRSKSMTSELEEMEYEQQPAPVPSMEKKRTVYQMALNKLDEILAAAQQTISASESPG
Sbjct: 781 TISLRSKSMTSELEEMEYEQQPAPVPSMEKKRTVYQMALNKLDEILAAAQQTISASESPG 840
Query: 841 PGGLASLGKHRPKGFFATESSFDPHHRAQPSYERPSFLPPGPGLMLRQKSIGAAEDDRPY 900
PGGLASLGKHRPKGFFATESSFDPHHRAQPSYERPSFLPPGPGLMLRQKSIGAAEDDRPY
Sbjct: 841 PGGLASLGKHRPKGFFATESSFDPHHRAQPSYERPSFLPPGPGLMLRQKSIGAAEDDRPY 900
Query: 901 LAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPVPSSSGRLTPSPRGGPFNPGSGG 960
LAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPVPSSSGRLTPSPRGGPFNPGSGG
Sbjct: 901 LAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPVPSSSGRLTPSPRGGPFNPGSGG 960
Query: 961 PLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHP 1020
PLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHP
Sbjct: 961 PLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHP 1020
Query: 1021 PHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGP 1080
PHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGP
Sbjct: 1021 PHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGP 1080
Query: 1081 ALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQP 1140
ALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQP
Sbjct: 1081 ALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQP 1140
Query: 1141 PPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSP 1200
PPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSP
Sbjct: 1141 PPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSP 1200
Query: 1201 APAMSPVPPSPSPVPTPASPSGPATLDFTSQFGAALVGAARREGGWQNEARRRSTLFLST 1260
APAMSPVPPSPSPVPTPASPSGPATLDFTSQFGAALVGAARREGGWQNEARRRSTLFLST
Sbjct: 1201 APAMSPVPPSPSPVPTPASPSGPATLDFTSQFGAALVGAARREGGWQNEARRRSTLFLST 1260
Query: 1261 DAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGAGSRAY 1320
DAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGAGSRAY
Sbjct: 1261 DAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGAGSRAY 1320
Query: 1321 GGGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKESSEGGGAPQPPPRP 1380
GGGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKESSEGGGAPQPPPRP
Sbjct: 1321 GGGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKESSEGGGAPQPPPRP 1380
Query: 1381 PSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAA 1440
PSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAA
Sbjct: 1381 PSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAA 1440
Query: 1441 RRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQP 1500
RRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQP
Sbjct: 1441 RRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQP 1500
Query: 1501 RAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGE 1560
RAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGE
Sbjct: 1501 RAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGE 1560
Query: 1561 FLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDST 1620
FLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDST
Sbjct: 1561 FLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDST 1620
Query: 1621 ASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDS 1680
ASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDS
Sbjct: 1621 ASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDS 1680
Query: 1681 RSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGS 1740
RSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGS
Sbjct: 1681 RSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGS 1740
Query: 1741 STPGPPYPPQLMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLAL 1800
STPGPPYPPQLMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLAL
Sbjct: 1741 STPGPPYPPQLMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLAL 1800
Query: 1801 RACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLAQPQA 1860
RACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLAQPQA
Sbjct: 1801 RACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLAQPQA 1860
Query: 1861 SALATVKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQ 1920
SALATVKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQ
Sbjct: 1861 SALATVKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQ 1920
Query: 1921 RQRLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGVSPTAAAAPGATSPSASSSSTST 1980
RQRLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGVSPTAAAAPGATSPSASSSSTST
Sbjct: 1921 RQRLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGVSPTAAAAPGATSPSASSSSTST 1980
Query: 1981 RHLQGVEFEMRPPLLRRAPSPSLLPASEHKVSPAPRPSSLPILPSGPLYPGLFDIRGSPT 2040
RHLQGVEFEMRPPLLRRAPSPSLLPASEHKVSPAPRPSSLPILPSGPLYPGLFDIRGSPT
Sbjct: 1981 RHLQGVEFEMRPPLLRRAPSPSLLPASEHKVSPAPRPSSLPILPSGPLYPGLFDIRGSPT 2040
Query: 2041 GGAGGSADPFAPVFVPPHPGISGGLGGALSGASRSLSPTRLLSLPPDKPFGAKPLGFWTK 2100
GGAGGSADPFAPVFVPPHPGISGGLGGALSGASRSLSPTRLLSLPPDKPFGAKPLGFWTK
Sbjct: 2041 GGAGGSADPFAPVFVPPHPGISGGLGGALSGASRSLSPTRLLSLPPDKPFGAKPLGFWTK 2100
Query: 2101 FDVADWLEWLGLAEHRAQFLDHEIDGSHLPALTKEDYVDLGVTRVGHRMNIDRALKFFLE 2160
FDVADWLEWLGLAEHRAQFLDHEIDGSHLPALTKEDYVDLGVTRVGHRMNIDRALKFFLE
Sbjct: 2101 FDVADWLEWLGLAEHRAQFLDHEIDGSHLPALTKEDYVDLGVTRVGHRMNIDRALKFFLE 2160
Query: 2161 R 2161
R
Sbjct: 2161 R 2161
>gi|226817313 SH3 and multiple ankyrin repeat domains 2 isoform 1
[Homo sapiens]
Length = 1849
Score = 1258 bits (3255), Expect = 0.0
Identities = 890/2227 (39%), Positives = 1125/2227 (50%), Gaps = 444/2227 (19%)
Query: 1 MTHSPATSEDEERHSASECPEGGSESDSSPDGPGRGP-RGTRGQGSGAPGSLASVRGLQG 59
M SP +SEDE S S+ G SESDSS + R T + GA
Sbjct: 1 MPRSPTSSEDEMAQSFSDYSVG-SESDSSKEETIYDTIRATAEKPGGAR----------- 48
Query: 60 RSMSVPDDAHFSMMVFRIGIPDLHQTKCLRFNPDATIWTAKQQVLCALSESLQDVLNYGL 119
+++ + +V R+ I DL QTKC+RFNPDAT+W AKQ++LC L++SL+DVLNYGL
Sbjct: 49 -----TEESQGNTLVIRVVIHDLQQTKCIRFNPDATVWVAKQRILCTLTQSLKDVLNYGL 103
Query: 120 FQPATSGRDANFLEEERLLREYPQSFEKGVPYLEFRYKTRVYKQTNLDEKQLAKLHTKTG 179
FQPA++GRD FL+EERLLREYPQ +GVP LEFRYK RVYKQ +LDEKQLAKLHTKT
Sbjct: 104 FQPASNGRDGKFLDEERLLREYPQPVGEGVPSLEFRYKKRVYKQASLDEKQLAKLHTKTN 163
Query: 180 LKKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAH 239
LKK ++++Q +K+ ++LD+GLDPN+HD ++GETPLTLAAQ + SVEVI+ L GGAH
Sbjct: 164 LKKCMDHIQHRLVEKITKMLDRGLDPNFHDPETGETPLTLAAQLDDSVEVIKALKNGGAH 223
Query: 240 IDFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCEL 299
+DFRA+DGMTALHKAA AR+ +AL LL+LG SP+YKD GLTPL+HTA+VGGDP CCEL
Sbjct: 224 LDFRAKDGMTALHKAARARNQVALKTLLELGASPDYKDSYGLTPLYHTAIVGGDPYCCEL 283
Query: 300 LLFNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNK 359
LL A + DENGW EIHQAC+ GH QHLEHLLFYGA+ AQNASGNTALHICALYN+
Sbjct: 284 LLHEHATVCCKDENGWHEIHQACRYGHVQHLEHLLFYGADMSAQNASGNTALHICALYNQ 343
Query: 360 ETCARILLYRGADKDVKNNNGQTPFQVAVIAGNFELGELIRNHREQDVVPFQESPKYAAR 419
++CAR+LL+RG +K++KN N QTPFQVA+IAGNFEL E I+NH+E D+VPF+E+P Y+ R
Sbjct: 344 DSCARVLLFRGGNKELKNYNSQTPFQVAIIAGNFELAEYIKNHKETDIVPFREAPAYSNR 403
Query: 420 RRGPPGTGLTVPPALLRANSDTSM--ALPDWMVFSAPGAASSGAPGPTSGSQGQSQPSAP 477
RR PP T L P LLR+NSD ++ + PDW V S A S + P Q S+P
Sbjct: 404 RRRPPNT-LAAPRVLLRSNSDNNLNASAPDWAVCST--ATSHRSLSPQLLQQMPSKPEGA 460
Query: 478 TTKLSSGTLRSASSPRGARARSPSRGR---HPEDAKR-QPR---GRPSSSGTPREGPAGG 530
+ S G R+RSPS R ED KR QP G P + G ++ +
Sbjct: 461 AKTIGSYV-------PGPRSRSPSLNRLGGAGEDGKRPQPLWHVGSPFALGANKDSLS-- 511
Query: 531 TGGSGGPGGSLGSRGRRRKLYSAVPGRSFMAVKSYQAQAEGEISLSKGEKIKVLSIGEGG 590
+ G +RKLYSAVPGR F+AVK YQ Q +GEI L +G+++KVLSIGEGG
Sbjct: 512 ---------AFEYPGPKRKLYSAVPGRLFVAVKPYQPQVDGEIPLHRGDRVKVLSIGEGG 562
Query: 591 FWEGQVKGRVGWFPSDCLEEVANRSQESKQESRSDKAKRLFRHYTVGSYDSFDAPSLMDG 650
FWEG +G +GWFP++C+EEV + ++S+ E+R+D++K+LFRHYTVGSYDSFD
Sbjct: 563 FWEGSARGHIGWFPAECVEEVQCKPRDSQAETRADRSKKLFRHYTVGSYDSFDT------ 616
Query: 651 IGPGSDYIIKEKTVLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGV 710
SD II+EKTV+LQKKD+EGFGFVLRGAKA TPIEEFTPTPAFPALQYLESVDEGGV
Sbjct: 617 ---SSDCIIEEKTVVLQKKDNEGFGFVLRGAKADTPIEEFTPTPAFPALQYLESVDEGGV 673
Query: 711 AWRAGLRMGDFLIEVNGQNVVKVGHRQVVNMIRQGGNTLMVKVVMVTRHPDMDEAVHKKA 770
AW+AGLR GDFLIEVN +NVVKVGHRQVVNMIRQGGN L++KVV VTR+ D D+ KKA
Sbjct: 674 AWQAGLRTGDFLIEVNNENVVKVGHRQVVNMIRQGGNHLVLKVVTVTRNLDPDDTARKKA 733
Query: 771 PQQAKRLPPPTISLRSKSMTSELEEMEYEQQPAPVPSMEKKRTVYQMALNKLDEILAAAQ 830
P KR P ++LRSKSMTSELEE+ S+ KK+ +K +EI+ A++
Sbjct: 734 PPPPKRAPTTALTLRSKSMTSELEEL------VDKASVRKKK-------DKPEEIVPASK 780
Query: 831 QTISASESPGPGGLASLGKHRPKGFFATESSFDPHHRAQ---------PSYERPSFLPPG 881
+ +A +A++ + F S + + Q P + FL
Sbjct: 781 PSRAAENMAVEPRVATIKQRPSSRCFPAGSDMNSVYERQGIAVMTPTVPGSPKAPFLGIP 840
Query: 882 PGLMLRQKSI-------GAAEDDRPYLAPPAMKFSRSLSVPG-SEDIPPPPTTSPPEPPY 933
G M RQKSI G E++R +LAPP +KF+RSLS+P SEDIPPPP + PP PP
Sbjct: 841 RGTMRRQKSIDSRIFLSGITEEERQFLAPPMLKFTRSLSMPDTSEDIPPPPQSVPPSPPP 900
Query: 934 STP--------PVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREK 985
+P P P G + P+ FN S + SPA+ REK
Sbjct: 901 PSPTTYNCPKSPTPRVYGTIKPA-----FNQNSAAKV---SPAT----RSDTVATMMREK 948
Query: 986 SLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQP 1045
+Y L + +A GPQ
Sbjct: 949 GMYFRRELDRYSLDSEDLYSRNA---------------------------------GPQA 975
Query: 1046 SLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRG 1105
+ R RG Q P Y ++ + AS A+YVPA+ R
Sbjct: 976 NFRNKRG-------------------------QMPENPYSEV-GKIASKAVYVPAKPAR- 1008
Query: 1106 RKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPST 1165
RKG LVKQ+ VE P+K SIPIPTII+K PST
Sbjct: 1009 RKGMLVKQSNVEDSPEK---------------------------TCSIPIPTIIVKEPST 1041
Query: 1166 SSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPSPVPTPASPSGPAT 1225
SSSG+SSQGSS E +P PEP P+ +
Sbjct: 1042 SSSGKSSQGSSMEIDPQA-PEP-----------------------------PSQLRPDES 1071
Query: 1226 LDFTSQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHS 1285
L +S F AA+ GA R+ + EARR S FLSTD GDED G G P PR R S
Sbjct: 1072 LTVSSPFAAAIAGAV-RDREKRLEARRNSPAFLSTDLGDEDVGLG------PPAPRTRPS 1124
Query: 1286 KSIDEGMFSAEPYLRLESA-------------------GSGAGYGGYGAGSRAYGGGGGS 1326
+EG F+ E S+ S G G S + G S
Sbjct: 1125 MFPEEGDFADEDSAEQLSSPMPSATPREPENHFVGGAEASAPGEAGRPLNSTSKAQGPES 1184
Query: 1327 -----SAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKESSEGGGAPQPPPRPP 1381
SA + P VHPLTG+ LDP+SPL LAL+AR+RA+KES +G P
Sbjct: 1185 SPAVPSASSGTAGPGNYVHPLTGRLLDPSSPLALALSARDRAMKESQQGPKGEAPKADLN 1244
Query: 1382 SPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAAR 1441
P Y P S A V R P E Y LG K +
Sbjct: 1245 KPLYIDTKMRP---SLDAGFPTVTRQNTRGPLRRQETENKYETDLGRDRKG------DDK 1295
Query: 1442 RSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPR 1501
+++L + T+ LL + H + +A EE E+ + ++
Sbjct: 1296 KNMLIDIMDTSQQKSAGLLMV-------HTVDATKLDNALQEEDEKAEVEMK-----PDS 1343
Query: 1502 APVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRA---SEENGLPLLVLPPPAPSVDVED 1558
+P G +G +P + P T E LP + PPP SVD+ D
Sbjct: 1344 SPSEVPEGVSETEGALQISAAPEPTTVPGRTIVAVGSMEEAVILPFRIPPPPLASVDL-D 1402
Query: 1559 GEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLD 1618
+F+F EPLPPPLEF+NSF+ P+ AA+ P L
Sbjct: 1403 EDFIFTEPLPPPLEFANSFDIPDDR---------------------------AASVPALS 1435
Query: 1619 STASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEV 1678
S + +L D P + PA P P DSGIEEV
Sbjct: 1436 DLVKQKKSDTPQSPSLNSSQPTNSADSKKPASLSNCLPASFLPPP-ESFDAVADSGIEEV 1494
Query: 1679 DSRSSSDHPLE---TISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQ 1735
DSRSSSDH LE TIS+ S++S+LS+EGG E +DT Y DGQ
Sbjct: 1495 DSRSSSDHHLETTSTISTVSSISTLSSEGG-----------------ENVDTCTVYADGQ 1537
Query: 1736 AFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTD 1795
AF P PP P M P + AL + + P P P
Sbjct: 1538 AFMVDKPPVPPKPK--MKPIIHKSNALYQDALVEEDVDSFVIPPPAPPPP---------- 1585
Query: 1796 GLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPL 1855
P + +P + V P S L W + P L GP
Sbjct: 1586 -------------------PGSAQPGMAKVLQPRTSKL------WGDVTEIKSPILSGP- 1619
Query: 1856 AQPQASALATVKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYVPER 1915
KA++ISEL+S LQQ A G G DS G S
Sbjct: 1620 -----------KANVISELNSILQQMNREKLA---------KPGEGLDSPMGAKS----- 1654
Query: 1916 TSSLQRQRLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPTGT-GVSPTAAAAPGATSPSAS 1974
+SL + P + +GT + T PG + P
Sbjct: 1655 --------------ASLAPR----------SPEIMSTISGTRSTTVTFTVRPGTSQPITL 1690
Query: 1975 SSSTSTRHLQGVEFEMRPPLLRRAPSPSLLPASEHKVSPAPRPSSLPILPSGPLYPGLFD 2034
S + ++E R RRAPSP + P +K P P S P +F
Sbjct: 1691 QS-------RPPDYESRTSGTRRAPSPVVSPTEMNK-ETLPAPLSAATASPSPALSDVFS 1742
Query: 2035 IRGSPTGGAGGSADPFAPVFVPPHPGISGGLGGALSGASRSLSPTRLLSLPPDKPFGAKP 2094
+ P G +P +G SRS SP+ L +KPF KP
Sbjct: 1743 LPSQPPSGDLFGLNP--------------------AGRSRSPSPSILQQPISNKPFTTKP 1782
Query: 2095 LGFWTKFDVADWLEWLGLAEHRAQFLDHEIDGSHLPALTKEDYVDLGVTRVGHRMNIDRA 2154
+ WTK DVADWLE L L EH+ F+D+EIDGSHLP L KED +DLGVTRVGHRMNI+RA
Sbjct: 1783 VHLWTKPDVADWLESLNLGEHKEAFMDNEIDGSHLPNLQKEDLIDLGVTRVGHRMNIERA 1842
Query: 2155 LKFFLER 2161
LK L+R
Sbjct: 1843 LKQLLDR 1849
>gi|122937241 SH3 and multiple ankyrin repeat domains 3 [Homo sapiens]
Length = 1747
Score = 900 bits (2326), Expect = 0.0
Identities = 677/1753 (38%), Positives = 859/1753 (49%), Gaps = 247/1753 (14%)
Query: 71 SMMVFRIGIPDLHQTKCLRFNPDATIWTAKQQVLCALSESLQDVLNYGLFQPATSGRDAN 130
S +V R+GIPDL QTKCLR +P A +W AKQ+VLCAL+ SLQD LNYGLFQP + GR
Sbjct: 7 SAVVVRVGIPDLQQTKCLRLDPAAPVWAAKQRVLCALNHSLQDALNYGLFQPPSRGRAGK 66
Query: 131 FLEEERLLREYPQSFEKGVPYLEFRYKTRVYKQTNLDEKQLAKLHTKTGLKKFLEYVQLG 190
FL+EERLL+EYP + + +PYLEFRYK RVY Q +D+KQ AKLHTK LKKF++YVQL
Sbjct: 67 FLDEERLLQEYPPNLDTPLPYLEFRYKRRVYAQNLIDDKQFAKLHTKANLKKFMDYVQLH 126
Query: 191 TSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMTA 250
++DKVARLLDKGLDPN+HD DSGE PL+LAAQ + + ++++ L GGAH+DFR RDG+TA
Sbjct: 127 STDKVARLLDKGLDPNFHDPDSGECPLSLAAQLDNATDLLKVLKNGGAHLDFRTRDGLTA 186
Query: 251 LHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGIA 310
+H A R+ ALT LLDLG SP+YKD RGLTPL+H+A+ GGD CCELLL + AQLGI
Sbjct: 187 VHCATRQRNAAALTTLLDLGASPDYKDSRGLTPLYHSALGGGDALCCELLLHDHAQLGIT 246
Query: 311 DENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILLYRG 370
DENGWQEIHQAC+ GH QHLEHLLFYGA+ GAQNASGNTALHICALYN+E+CAR+LL+RG
Sbjct: 247 DENGWQEIHQACRFGHVQHLEHLLFYGADMGAQNASGNTALHICALYNQESCARVLLFRG 306
Query: 371 ADKDVKNNNGQTPFQVAVIAGNFELGELIRNHREQDVVPFQESPKYAARRRGPPGTGLTV 430
A++DV+N N QT FQVA+IAGNFEL E+I+ H++ DVVPF+E+P YA RRR +GL
Sbjct: 307 ANRDVRNYNSQTAFQVAIIAGNFELAEVIKTHKDSDVVPFRETPSYAKRRRLAGPSGLAS 366
Query: 431 PPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSAS 490
P L R+ SD ++ G A A S G S S P L
Sbjct: 367 PRPLQRSASDINLK----------GEAQPAA------SPGPSLRSLPHQLLLQRLQEEKD 410
Query: 491 SPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPREGPAGGTGGSGGPGGSLGS------- 543
R A S G R S P GP G G P G+ S
Sbjct: 411 RDRDADQESNISG------PLAGRAGQSKISDPGPGPGGVGGAPLPPPGAPRSCIRIRAR 464
Query: 544 ------------RGRRRKLYSAVPGRSFMAVKSYQAQAEGEISLSKGEKIKVLSIGEGGF 591
RG +RKLYSAVPGR F+AVK++ Q EGEI L +GE +KVLSIGEGGF
Sbjct: 465 FPAPPAPPAPPPRGPKRKLYSAVPGRKFIAVKAHSPQGEGEIPLHRGEAVKVLSIGEGGF 524
Query: 592 WEGQVKGRVGWFPSDCLEEVANRSQESKQESRSDKAKRLFRHYTVGSYDSFDAPSLMDGI 651
WEG VKGR GWFP+DC+EEV R +++ E+R D+ KRLFRHYTVGSYDS + S
Sbjct: 525 WEGTVKGRTGWFPADCVEEVQMRQHDTRPETREDRTKRLFRHYTVGSYDSLTSHS----- 579
Query: 652 GPGSDYIIKEKTVLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVA 711
DY+I +K +LQK+D EGFGFVLRGAKA+TPIEEFTPTPAFPALQYLESVD GVA
Sbjct: 580 ----DYVIDDKVAVLQKRDHEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDVEGVA 635
Query: 712 WRAGLRMGDFLIEVNGQNVVKVGHRQVVNMIRQGGNTLMVKVVMVTRHPDMDEAVHKKAP 771
WRAGLR GDFLIEVNG NVVKVGH+QVV +IRQGGN L++KVV VTR P+ D A ++AP
Sbjct: 636 WRAGLRTGDFLIEVNGVNVVKVGHKQVVALIRQGGNRLVMKVVSVTRKPEEDGA-RRRAP 694
Query: 772 QQAKRLPPPTISLRSKSMTSELEEMEYEQQPAPVPSMEKKRTVYQMALNKLDEILAAAQQ 831
KR P T++LRSKSMT+ELEE+ S+ +++ KLDE+LAAA +
Sbjct: 695 PPPKRAPSTTLTLRSKSMTAELEEL---------ASIRRRKG------EKLDEMLAAAAE 739
Query: 832 TISASESPGPGGLASLGKHRPKGFFATESSFDPHHRAQ--PSYER-PSFLPPGPGLMLRQ 888
+ A+ K RP T + Q P E+ P L G + R
Sbjct: 740 PTLRPDIADADSRAATVKQRPTSRRITPAEISSLFERQGLPGPEKLPGSLRKG---IPRT 796
Query: 889 KSIGAAEDDRPYLAPPAMKFSRSLS----VPGSEDIPPPPTTSPPEPP------------ 932
KS+G +D + +F RS S V IPPPP T+PP PP
Sbjct: 797 KSVG---EDEKLASLLEGRFPRSTSMQDPVREGRGIPPPPQTAPPPPPAPYYFDSGPPPA 853
Query: 933 YSTPPVPSSSGRLTPSPRGGPFNPGSGGPLPASS-----PASFDGPSP-PDTRVGSR--- 983
+S PP P GR + R F PG L A + P + GP P P+ + +R
Sbjct: 854 FSPPPPP---GRAYDTVRSS-FKPGLEARLGAGAAGLYEPGAALGPLPYPERQKRARSMI 909
Query: 984 --EKSLYHSG--PLPPAHHHPPHHHHHHAPPPQPHHHHAH---------PPHPPEMETGG 1030
+ S SG P PP PP PP P +A+ P P+
Sbjct: 910 ILQDSAPESGDAPRPPPAATPPERPKRRPRPPGPDSPYANLGAFSASLFAPSKPQRRKSP 969
Query: 1031 -----SPDDPPPRLALGPQPSLRGWRGGGPSPTPGA----PSPSHHGSAGGG--GGSSQG 1079
+D R AL G P P G+ PSP+H G GG G+ G
Sbjct: 970 LVKQLQVEDAQERAALAV---------GSPGPGGGSFAREPSPTHRGPRPGGLDYGAGDG 1020
Query: 1080 PALRYFQLPP---------RAASAAMYVPARSGR--GRKGPLVKQTKVEGEPQKGGGLPP 1128
P L + P R ++ + V A G G P ++ ++ E G G P
Sbjct: 1021 PGLAFGGPGPAKDRRLEERRRSTVFLSVGAIEGSAPGADLPSLQPSRSIDERLLGTG-PT 1079
Query: 1129 A------PSPTSPASPQPPPAVAAPSEKNSI-PIPTIIIKAPSTSSSGRSSQGSSTEAEP 1181
A PSP S P PS I P+ + S + +++ + ++
Sbjct: 1080 AGRDLLLPSPVSALKPLVSGPSLGPSGSTFIHPLTGKPLDPSSPLALALAARERALASQA 1139
Query: 1182 PTQ-PEPTGGGGGGGSSPSPAPAMSPVPPSPSPVPTPASPSGPATLDFTSQFGAALVGAA 1240
P++ P P P + P S SP PA + ++ A V
Sbjct: 1140 PSRSPTPVHSPDADRPGPLFVDVQARDPERGSLASPAFSPRSPAWIPVPARREAEKVPRE 1199
Query: 1241 RREGGWQNEARRRSTLFLS------------TDAGDEDGGDGGLGTGAAPGPRLRHSKSI 1288
R+ ++ S L S T G E GG P L +
Sbjct: 1200 ERKSPEDKKSMILSVLDTSLQRPAGLIVVHATSNGQEPSRLGGAEEERPGTPELAPAPMQ 1259
Query: 1289 DEGMFSAEPYLRLESAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALD 1348
+ P R + G G G GS F LPP L + +
Sbjct: 1260 SAAVAEPLPSPRAQPPGGTPADAGPGQGS---SEEEPELVFAVNLPPAQL-SSSDEETRE 1315
Query: 1349 PASPLGLALAARERA---LKESSEGGGAPQPP--PRPPSPRYEA-PPPTPHHHSPHAHHE 1402
+ +GL E A L + G P P P P S + + PPP P + E
Sbjct: 1316 ELARIGLVPPPEEFANGVLLATPLAGPGPSPTTVPSPASGKPSSEPPPAPESAADSGVEE 1375
Query: 1403 PVLRLWGASPPDP------ARRELGYRAGLGSQEKSLPASPP--AARRSLLHRLPPTAP- 1453
R S DP + + L S+ L + A + L PP P
Sbjct: 1376 ADTR----SSSDPHLETTSTISTVSSMSTLSSESGELTDTHTSFADGHTFLLEKPPVPPK 1431
Query: 1454 -------GVGPL-----LLQLGTEP---PAPHPGVSKPWRSAAPEEPERLPLHVRFLENC 1498
G GP+ LL+ ++ H S SAA P R+L
Sbjct: 1432 PKLKSPLGKGPVTFRDPLLKQSSDSELMAQQHHAASAGLASAAG------PARPRYLFQR 1485
Query: 1499 QPRA---PVTS-GRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSV 1554
+ + PV S G P +D P V R + + EE L L PA
Sbjct: 1486 RSKLWGDPVESRGLPGPEDDKPTVISELSSRLQQLNKDTRSLGEEPVGGLGSLLDPAKKS 1545
Query: 1555 DVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPL-----PPVPPPA 1609
+ L L +S SP PG P+ P+ PV P +
Sbjct: 1546 PIAAAR------LFSSLGELSSISAQRSPGGPGGGASYSVRPSGRYPVARRAPSPVKPAS 1599
Query: 1610 V-----------------AAAPPT-LDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPP 1651
+ PPT L S++ S+ EV + + SA P P P
Sbjct: 1600 LERVEGLGAGAGGAGRPFGLTPPTILKSSSLSIPHEPKEVRFVVRSVSARSRSPSPSPLP 1659
Query: 1652 APAA-PAPAAPQP 1663
+PA+ P P AP P
Sbjct: 1660 SPASGPGPGAPGP 1672
Score = 154 bits (389), Expect = 9e-37
Identities = 312/1171 (26%), Positives = 411/1171 (35%), Gaps = 269/1171 (22%)
Query: 1104 RGRKGP-LVKQTKVEGEPQKGGGLPPAPSPTSPASPQP------PPAVAAPSEKNSIP-- 1154
R RKG L + EP + A S + +P P +++ E+ +P
Sbjct: 723 RRRKGEKLDEMLAAAAEPTLRPDIADADSRAATVKQRPTSRRITPAEISSLFERQGLPGP 782
Query: 1155 --IPTIIIKA-PSTSSSGRSSQ-GSSTEAEPP---TQPEPTGGGGGGGSSPSPAPAMSPV 1207
+P + K P T S G + S E P + +P G G P AP P
Sbjct: 783 EKLPGSLRKGIPRTKSVGEDEKLASLLEGRFPRSTSMQDPVREGRGIPPPPQTAPPPPPA 842
Query: 1208 P----PSPSPVPTPASPSGPATLDFTSQF----------GAALV---GAARREGGWQNEA 1250
P P P +P P G A S F GAA + GAA +
Sbjct: 843 PYYFDSGPPPAFSPPPPPGRAYDTVRSSFKPGLEARLGAGAAGLYEPGAALGPLPYPERQ 902
Query: 1251 RRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGY 1310
+R ++ + D+ E G A P R P R G + Y
Sbjct: 903 KRARSMIILQDSAPESGDAPRPPPAATPPER---------------PKRRPRPPGPDSPY 947
Query: 1311 GGYGAGSRAYGGGGGSSAFTSFLPPR---PLVHPLTGKALDPASPLGLALAARERALKES 1367
GA S +S F P R PLV L + + L A+
Sbjct: 948 ANLGAFS--------ASLFAPSKPQRRKSPLVKQLQVEDAQERAAL---------AVGSP 990
Query: 1368 SEGGGAPQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLG 1427
GGG+ R PSP + P P + A P L G P R E R+ +
Sbjct: 991 GPGGGSFA---REPSPTHRGPRPGGLDYG--AGDGPGLAFGGPGPAKDRRLEERRRSTVF 1045
Query: 1428 SQEKSLPASPPAA-------RRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSA 1480
++ S P A RS+ RL T P G LL
Sbjct: 1046 LSVGAIEGSAPGADLPSLQPSRSIDERLLGTGPTAGRDLL-------------------- 1085
Query: 1481 APEEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRA---- 1536
LP V L+ P+ SG PS G P P P+SP A
Sbjct: 1086 -------LPSPVSALK------PLVSG---PSLGPSGSTFIHPLTGKPLDPSSPLALALA 1129
Query: 1537 SEENGLPLLV---LPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLP 1593
+ E L P P S D + LFV+ E + SP +P
Sbjct: 1130 ARERALASQAPSRSPTPVHSPDADRPGPLFVDVQARDPERGSLASPAFSPRSPAW----- 1184
Query: 1594 DTPAPATPLPPVPPPAVAAAPPTLDSTASSL----------------TSYDSEVATLTQG 1637
P PA P +P S S+ TS E + L
Sbjct: 1185 -IPVPARREAEKVPREERKSPEDKKSMILSVLDTSLQRPAGLIVVHATSNGQEPSRLGGA 1243
Query: 1638 ASAAPGDPH-PPGPPAPAAPAPAAPQPGPDPPPGT--DSGIEEVDSRSSSDHPLETISSA 1694
PG P P P AA A P P PP GT D+G + S +
Sbjct: 1244 EEERPGTPELAPAPMQSAAVAEPLPSPRAQPPGGTPADAGPGQGSSEEEPELVFAVNLPP 1303
Query: 1695 STLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTP 1754
+ LSS E A G+ PE V A G S P P
Sbjct: 1304 AQLSSSDEETREEL-----ARIGLVPPPEEFANGVLLATPLAGPGPSPTTVPSPASGKPS 1358
Query: 1755 SKLR-GRALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPT---AG 1810
S+ A G+ + DP T+ T+S + + L + SG T
Sbjct: 1359 SEPPPAPESAADSGVEEADTRSSSDPHLETTSTISTVSS----MSTLSSESGELTDTHTS 1414
Query: 1811 VAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLAQ-PQASALATVKAS 1869
A G + E PPVP P P L PL + P +K S
Sbjct: 1415 FADGHTFLL-EKPPVP--------------------PKPKLKSPLGKGPVTFRDPLLKQS 1453
Query: 1870 IISELSSKLQQF---GGSSAAGGALP----------W-----ARGGSGGGGDSHHGGASY 1911
SEL ++ G +SAAG A P W +RG G D +
Sbjct: 1454 SDSELMAQQHHAASAGLASAAGPARPRYLFQRRSKLWGDPVESRGLPGPEDDK----PTV 1509
Query: 1912 VPERTSSLQRQRLSDDSQSSLLSKPVS---SLFQNWPKPPLPPL----PTGTGVSPTAAA 1964
+ E +S LQ+ L+ D++S L +PV SL K P+ G S +A
Sbjct: 1510 ISELSSRLQQ--LNKDTRS-LGEEPVGGLGSLLDPAKKSPIAAARLFSSLGELSSISAQR 1566
Query: 1965 APGATSPSASSSSTSTRHLQGVEFEMRPPLLRRAPSPSLLPASEHKVSPAPRPSSLPILP 2024
+PG AS S V R P+ RRAPSP + PAS +V
Sbjct: 1567 SPGGPGGGASYS---------VRPSGRYPVARRAPSP-VKPASLERVE------------ 1604
Query: 2025 SGPLYPGLFDIRGSPTGGAGGSADPF----------APVFVPPHPGISGGLGGALSGASR 2074
GL GAGG+ PF + + +P P + ++S SR
Sbjct: 1605 ------GL-------GAGAGGAGRPFGLTPPTILKSSSLSIPHEPKEVRFVVRSVSARSR 1651
Query: 2075 SLSPTRLLSLP---------PDKPFGAKPLGFWTKFDVADWLEWLGLAEHRAQFLDHEID 2125
S SP+ L S P +PF KPL W+KFDV DWLE + L EHR +F DHEI+
Sbjct: 1652 SPSPSPLPSPASGPGPGAPGPRRPFQQKPLQLWSKFDVGDWLESIHLGEHRDRFEDHEIE 1711
Query: 2126 GSHLPALTKEDYVDLGVTRVGHRMNIDRALK 2156
G+HLPALTK+D+V+LGVTRVGHRMNI+RAL+
Sbjct: 1712 GAHLPALTKDDFVELGVTRVGHRMNIERALR 1742
Score = 132 bits (332), Expect = 4e-30
Identities = 260/1035 (25%), Positives = 347/1035 (33%), Gaps = 243/1035 (23%)
Query: 941 SSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREK-SLYHSGPLPPAHHH 999
+S R+TP+ F G P P P S P VG EK + G P +
Sbjct: 761 TSRRITPAEISSLFER-QGLPGPEKLPGSLRKGIPRTKSVGEDEKLASLLEGRFPRSTSM 819
Query: 1000 PPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTP 1059
PP P PP P ++G PPP + P P R + S P
Sbjct: 820 QDPVREGRGIPPPPQTAPPPPPAPYYFDSG-----PPPAFSPPPPPG-RAYDTVRSSFKP 873
Query: 1060 GAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGE 1119
G + G+AG P AA + P R R R +++ +
Sbjct: 874 GLEARLGAGAAG--------------LYEPGAALGPLPYPERQKRARSMIILQ----DSA 915
Query: 1120 PQKGGGLPPAPSPTSPASPQPPPAVAAP-SEKNSIPIPTIIIKAPSTSSSGRSSQGSSTE 1178
P+ G P P+ T P P+ P P S ++ + + APS +S +
Sbjct: 916 PESGDAPRPPPAATPPERPKRRPRPPGPDSPYANLGAFSASLFAPSKPQRRKSPLVKQLQ 975
Query: 1179 AEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPSPVPTPASPSGPATLDFTSQFGAALV- 1237
E + G SP P PSP P G LD+ + G L
Sbjct: 976 VEDAQERAALAVG-------SPGPGGGSFAREPSPTHRGPRPGG---LDYGAGDGPGLAF 1025
Query: 1238 GAARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPG---PRLRHSKSIDEGMFS 1294
G + E RRRST+FLS A + G+APG P L+ S+SIDE +
Sbjct: 1026 GGPGPAKDRRLEERRRSTVFLSVGAIE----------GSAPGADLPSLQPSRSIDERLLG 1075
Query: 1295 AEPY----LRLESAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPA 1350
P L L S S G G S T +HPLTGK LDP+
Sbjct: 1076 TGPTAGRDLLLPSPVSALK-------PLVSGPSLGPSGST-------FIHPLTGKPLDPS 1121
Query: 1351 SPLGLALAARERALKESS----------------------------EGGGAPQPPPRPPS 1382
SPL LALAARERAL + E G P P S
Sbjct: 1122 SPLALALAARERALASQAPSRSPTPVHSPDADRPGPLFVDVQARDPERGSLASPAFSPRS 1181
Query: 1383 PRYEAPP--------PTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAG-------LG 1427
P + P P SP +L + S PA + + LG
Sbjct: 1182 PAWIPVPARREAEKVPREERKSPEDKKSMILSVLDTSLQRPAGLIVVHATSNGQEPSRLG 1241
Query: 1428 SQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPER 1487
E+ P +P A P + V L +PP P + P + ++ EEPE
Sbjct: 1242 GAEEERPGTPELAPA------PMQSAAVAEPLPSPRAQPPGGTPADAGPGQGSSEEEPEL 1295
Query: 1488 LPLHVRFLENCQPRAPVTSGRG------------PPSEDGPGV--------PPPSPRRSV 1527
+ F N P +S PP E GV P PSP +
Sbjct: 1296 V-----FAVNLPPAQLSSSDEETREELARIGLVPPPEEFANGVLLATPLAGPGPSP--TT 1348
Query: 1528 PPSPTSPRASEENGLPLLVLPPPAPSVDVEDG--EFLFVEPLPPPLEFSNSFEKPESPLT 1585
PSP S + S E PPPAP + G E P LE +++ S T
Sbjct: 1349 VPSPASGKPSSE--------PPPAPESAADSGVEEADTRSSSDPHLETTSTISTVSSMST 1400
Query: 1586 -PGPPHPLPDTPAPATP-------LPPVPPPAVAAAP----PTLDSTASSLTSYDSEVAT 1633
L DT PPVPP +P P S DSE+
Sbjct: 1401 LSSESGELTDTHTSFADGHTFLLEKPPVPPKPKLKSPLGKGPVTFRDPLLKQSSDSELMA 1460
Query: 1634 LTQGASAAPGDPHPPGPPAP-----------AAPAPAAPQPGPDPPPGT-----DSGIEE 1677
A++A G GP P P + PGP+ T S +++
Sbjct: 1461 QQHHAASA-GLASAAGPARPRYLFQRRSKLWGDPVESRGLPGPEDDKPTVISELSSRLQQ 1519
Query: 1678 V--DSRSSSDHPL------------------ETISSASTLSSLSAEGGGSAGGGGGAGAG 1717
+ D+RS + P+ SS LSS+SA+ + GG G GA
Sbjct: 1520 LNKDTRSLGEEPVGGLGSLLDPAKKSPIAAARLFSSLGELSSISAQ---RSPGGPGGGAS 1576
Query: 1718 VASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGPSGGLR 1777
+ P G+ P P P L ++ G GA G RP GL
Sbjct: 1577 YSVRP----------SGRYPVARRAPSPVKPASL---ERVEGLGAGAGGAGRP---FGLT 1620
Query: 1778 DPVTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKL 1837
P S ++S+ + +R+ S A P PLP+ +S P
Sbjct: 1621 PPTILKSSSLSIPHEPKEVRFVVRSVS------------ARSRSPSPSPLPSPASGP--- 1665
Query: 1838 LPWEEGPGPPPPPLP 1852
GPG P P P
Sbjct: 1666 -----GPGAPGPRRP 1675
Score = 43.1 bits (100), Expect = 0.003
Identities = 53/158 (33%), Positives = 65/158 (41%), Gaps = 39/158 (24%)
Query: 832 TISASESPG-PGGLASLGKHRPKGFFATESSFDPHHRAQPSYERPSFLPPGPGLMLRQKS 890
+ISA SPG PGG AS RP G + P R PS +P+ L GL
Sbjct: 1561 SISAQRSPGGPGGGASYSV-RPSGRY-------PVARRAPSPVKPASLERVEGL-----G 1607
Query: 891 IGAAEDDRPY-LAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPVPSSSGRLTPSP 949
GA RP+ L PP + S SLS+P P E + V + S +PSP
Sbjct: 1608 AGAGGAGRPFGLTPPTILKSSSLSIPHE----------PKEVRFVVRSVSARSRSPSPSP 1657
Query: 950 RGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSL 987
LP SPAS GP P R ++K L
Sbjct: 1658 ------------LP--SPASGPGPGAPGPRRPFQQKPL 1681
Score = 33.5 bits (75), Expect = 2.3
Identities = 121/531 (22%), Positives = 170/531 (32%), Gaps = 118/531 (22%)
Query: 1606 PPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGP 1665
PPP A TL + S+T+ E+A++ + + A A P P
Sbjct: 694 PPPPKRAPSTTLTLRSKSMTAELEELASIRRRKGEKLDE---------MLAAAAEPTLRP 744
Query: 1666 DPPPGTDSGIEEVDSRSSS--DHPLETISSASTLSSLSAEGG--------GSAGGGGGAG 1715
D I + DSR+++ P + + +SSL G GS G
Sbjct: 745 D--------IADADSRAATVKQRPTSRRITPAEISSLFERQGLPGPEKLPGSLRKGIPRT 796
Query: 1716 AGVASGPELLDTYVAYLDGQAFGGSSTPGP-------PYPPQLMTPSKLRGRALGASGGL 1768
V +L + L+G+ +S P P PPQ P A
Sbjct: 797 KSVGEDEKL----ASLLEGRFPRSTSMQDPVREGRGIPPPPQTAPPPP------PAPYYF 846
Query: 1769 RPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEP--EVPPVP 1826
GP P P +V + GL A AG AG EP + P+P
Sbjct: 847 DSGPPPAFSPPPPPGRAYDTVRSSFKPGLEARLG------AGAAG---LYEPGAALGPLP 897
Query: 1827 LPTASSLPRKLL-----PWEEGPGPPPPPL-------------PGP-------------- 1854
P R ++ E G P PPP PGP
Sbjct: 898 YPERQKRARSMIILQDSAPESGDAPRPPPAATPPERPKRRPRPPGPDSPYANLGAFSASL 957
Query: 1855 --LAQPQASALATVKASIISELSSKLQQFGGSSAAGGA------LPWARGGSGGGGDSHH 1906
++PQ VK + + + GS GG P RG GG D
Sbjct: 958 FAPSKPQRRKSPLVKQLQVEDAQERAALAVGSPGPGGGSFAREPSPTHRGPRPGGLDYGA 1017
Query: 1907 GGASYVPERTSSLQRQRLSDDSQSSLLSKPVSSLFQNWPKPPLPPLP---------TGTG 1957
G + + R ++ + S + V ++ + P LP L GTG
Sbjct: 1018 GDGPGLAFGGPGPAKDRRLEERRRSTVFLSVGAIEGSAPGADLPSLQPSRSIDERLLGTG 1077
Query: 1958 ---------VSPTAAAAPGATSPS-ASSSSTSTRHLQGVEFEMRPPL-LRRAPSPSLLPA 2006
SP +A P + PS S ST L G + PL L A L +
Sbjct: 1078 PTAGRDLLLPSPVSALKPLVSGPSLGPSGSTFIHPLTGKPLDPSSPLALALAARERALAS 1137
Query: 2007 SEHKVSPAPRPSSLPILPSGPLYPGLFDIRGSPTGGAGGSA-DPFAPVFVP 2056
SP P S P GPL+ + R G A P +P ++P
Sbjct: 1138 QAPSRSPTPVHSPDADRP-GPLFVDV-QARDPERGSLASPAFSPRSPAWIP 1186
>gi|169203021 PREDICTED: similar to Shank2E [Homo sapiens]
Length = 385
Score = 472 bits (1214), Expect = e-132
Identities = 238/393 (60%), Positives = 295/393 (75%), Gaps = 18/393 (4%)
Query: 1 MTHSPATSEDEERHSASECPEGGSESDSSPDGPGRGP-RGTRGQGSGAPGSLASVRGLQG 59
M SP +SEDE S S+ G SESDSS + R T + GA
Sbjct: 1 MPRSPTSSEDEMAQSFSDYSVG-SESDSSKEETIYDTIRATAEKPGGAR----------- 48
Query: 60 RSMSVPDDAHFSMMVFRIGIPDLHQTKCLRFNPDATIWTAKQQVLCALSESLQDVLNYGL 119
+++ + +V R+ I DL QTKC+RFNPDAT+W AKQ++LC L++SL+DVLNYGL
Sbjct: 49 -----TEESQGNTLVIRVVIHDLQQTKCIRFNPDATVWVAKQRILCTLTQSLKDVLNYGL 103
Query: 120 FQPATSGRDANFLEEERLLREYPQSFEKGVPYLEFRYKTRVYKQTNLDEKQLAKLHTKTG 179
FQPA++GRD FL+EERLLREYPQ +GVP LEFRYK RVYKQ +LDEKQLAKLHTKT
Sbjct: 104 FQPASNGRDGKFLDEERLLREYPQPVGEGVPSLEFRYKKRVYKQASLDEKQLAKLHTKTN 163
Query: 180 LKKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAH 239
LKK ++++Q +K+ ++LD+GLDPN+HD ++GETPLTLAAQ + SVEVI+ L GGAH
Sbjct: 164 LKKCMDHIQHRLVEKITKMLDRGLDPNFHDPETGETPLTLAAQLDDSVEVIKALKNGGAH 223
Query: 240 IDFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCEL 299
+DFRA+DGMTALHKAA AR+ +AL LL+LG SP+YKD GLTPL+HTA+VGGDP CCEL
Sbjct: 224 LDFRAKDGMTALHKAARARNQVALKTLLELGASPDYKDSYGLTPLYHTAIVGGDPYCCEL 283
Query: 300 LLFNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNK 359
LL A + DENGW EIHQAC+ GH QHLEHLLFYGA+ AQNASGNTALHICALYN+
Sbjct: 284 LLHEHATVCCKDENGWHEIHQACRYGHVQHLEHLLFYGADMSAQNASGNTALHICALYNQ 343
Query: 360 ETCARILLYRGADKDVKNNNGQTPFQVAVIAGN 392
++CAR+LL+RG +K++KN N QTPFQV I+ +
Sbjct: 344 DSCARVLLFRGGNKELKNYNSQTPFQVKEISAS 376
>gi|19743796 SH3 and multiple ankyrin repeat domains 2 isoform 2
[Homo sapiens]
Length = 281
Score = 231 bits (590), Expect = 4e-60
Identities = 135/247 (54%), Positives = 163/247 (65%), Gaps = 22/247 (8%)
Query: 655 SDYIIKEKTVLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRA 714
SD II+EKTV+LQKKD+EGFGFVLRGAKA TPIEEFTPTPAFPALQYLESVDEGGVAW+A
Sbjct: 30 SDCIIEEKTVVLQKKDNEGFGFVLRGAKADTPIEEFTPTPAFPALQYLESVDEGGVAWQA 89
Query: 715 GLRMGDFLIEVNGQNVVKVGHRQVVNMIRQGGNTLMVKVVMVTRHPDMDEAVHKKAPQQA 774
GLR GDFLIEVN +NVVKVGHRQVVNMIRQGGN L++KVV VTR+ D D+ KKAP
Sbjct: 90 GLRTGDFLIEVNNENVVKVGHRQVVNMIRQGGNHLVLKVVTVTRNLDPDDTARKKAPPPP 149
Query: 775 KRLPPPTISLRSKSMTSELEEMEYEQQPAPVPSMEKKRTVYQMALNKLDEILAAAQQTIS 834
KR P ++LRSKSMTSELEE+ S+ KK+ +K +EI+ A++ + +
Sbjct: 150 KRAPTTALTLRSKSMTSELEEL------VDKASVRKKK-------DKPEEIVPASKPSRA 196
Query: 835 ASESPGPGGLASLGKHRPKGFFATESSFDPHHRAQ---------PSYERPSFLPPGPGLM 885
A +A++ + F S + + Q P + FL G M
Sbjct: 197 AENMAVEPRVATIKQRPSSRCFPAGSDMNSVYERQGIAVMTPTVPGSPKAPFLGIPRGTM 256
Query: 886 LRQKSIG 892
RQKSIG
Sbjct: 257 RRQKSIG 263
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 149 bits (377), Expect = 2e-35
Identities = 281/1150 (24%), Positives = 390/1150 (33%), Gaps = 200/1150 (17%)
Query: 761 DMDEAVHKKAPQQAKRLPPPTI--SLRSKSMTSELEEMEYEQQPAPVPSMEK----KRTV 814
D H P K P P+ L K +T +E P PS+ K
Sbjct: 848 DSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKE-------TPTPSVVNLPFPKEGP 900
Query: 815 YQMALNKLDEILAAAQQTISASESPGPGGLASLGKHRPKGFFATESSFDPHHRAQPSYER 874
A + + + A +P P G+ + PKG ++ P + P+
Sbjct: 901 ATPAPKQAPALSMTSSSPKKARATPAPKGIPA--SPSPKGAPTPPAATPPSPKGGPATPS 958
Query: 875 PSFLPPGPGLMLRQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPP----------PP 924
P + P P PP+ K + P PP P
Sbjct: 959 PKWAPTPPAA-----------------TPPSPKGGPATPSPKGAPTPPAATPPSPKGGPA 1001
Query: 925 TTSP---PEPPYSTPPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVG 981
T SP P PP TPP P S TP P+G P + P P SPA+ P T
Sbjct: 1002 TPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPA 1061
Query: 982 SREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLAL 1041
+ S GP P+ P PP A PP P G P P P+ A
Sbjct: 1062 ATLPS-PKGGPATPSLKGAP------TPPA------ATPPSPK-----GGPATPSPKGA- 1102
Query: 1042 GPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPAR 1101
P P PSP G +P H G+ + P PP+ A PA
Sbjct: 1103 -PMPP----AATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPT---TPAA 1154
Query: 1102 SGRGRKGPLVKQTKVEGEPQKGGGLPPAP-----------SPTSPAS--PQPPPAVAAPS 1148
+ KG L +G P PP+P +PT+PA+ P P +A PS
Sbjct: 1155 TPPSPKGGLATPPP-KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS 1213
Query: 1149 EKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVP 1208
K + P +P + S +G+ T T P P GG +P P +P P
Sbjct: 1214 PKGAPTTPAATPPSPKGGLATPSPKGAPT-TPAATPPSPKGG------PATPPPKGAPTP 1266
Query: 1209 PSPSPVPTPASPSGPATLDFTSQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDEDGG 1268
P+ +P P+ G AT A+V +GG + + + G
Sbjct: 1267 PAATP---PSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGS 1323
Query: 1269 DGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGAG--YGGYGAGSRAYGGGGGS 1326
G AP P ++ P L + S G G
Sbjct: 1324 PGTPPPKGAPTP-----PAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSH 1378
Query: 1327 SAFTSFLPPRPLVHP-LTGKALDPASPLGLALAARER-ALKESSEGGGAPQ-----PPPR 1379
+ PP P P + DP SP + L+ ++ A + EG P PP
Sbjct: 1379 KGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAV 1438
Query: 1380 PPSPRYEAP---PPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPAS 1436
P +AP P +P + +P L +PP P + S K PA+
Sbjct: 1439 TPVSLKKAPATSAPKGGPATPSSKGDPTLP--AVTPPSPKEPPAPKQVATSSSPKKAPAT 1496
Query: 1437 PPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLE 1496
P L + P++P P +P AP A ++ P + E
Sbjct: 1497 PAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAP----------TATLLSKKTPATLAPKE 1546
Query: 1497 NCQPRAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDV 1556
P A P + P +P P + P +P+S AS PPA +
Sbjct: 1547 ALIPPAMTV----PSPKKTPAIPTP---KEAPATPSSKEASS----------PPAVTPST 1589
Query: 1557 EDGEFLFVEPLPPPLEFSNSFEKPESP--LTPGPPHPLPDTPAP-ATPL-PPVPPPAVAA 1612
G E L PP S S ++ +P +TP P P TPAP TP PPV P ++
Sbjct: 1590 YKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKD 1649
Query: 1613 APPTLDSTASSLTSYDSEVATLTQGASAAPGD---------PHPPGPPAPAAPAPAAPQ- 1662
+P S AS + V ++G A G P P P AP PQ
Sbjct: 1650 SP---TSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQT 1706
Query: 1663 ---PGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTL-----SSLSAEGGGSAGGGGGA 1714
PP D +++ S PL T++ A L SS +A+G ++ G
Sbjct: 1707 KKSSATSPPICPDP-----SAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGP 1761
Query: 1715 GA---GVASGPELLDTYVAYL-DGQAFGGSSTPGPPYPPQLMTPSKL-----RGRALGAS 1765
A AS P + L ++ S+ P PP L PS + + + L +S
Sbjct: 1762 LAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPL-APSPVPTLPPKQQFLPSS 1820
Query: 1766 GGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVP-- 1823
GL L P P +P A D LL L P + GV V V P
Sbjct: 1821 PGL------VLESPSKPLAP------ADEDELLPL-IPPEPISGGVPFQSVLVNMPTPKS 1867
Query: 1824 ---PVPLPTA 1830
PVP P+A
Sbjct: 1868 AGIPVPTPSA 1877
Score = 144 bits (363), Expect = 9e-34
Identities = 290/1183 (24%), Positives = 404/1183 (34%), Gaps = 199/1183 (16%)
Query: 770 APQQAKRLPPPTIS-LRSKSMTSELEEMEYEQQPAPVPSMEKKRTVYQMALNKLDEILAA 828
AP+ K +P P++ + T +++ + + APV S K+ + A+
Sbjct: 727 APEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASAT----AS 782
Query: 829 AQQTIS-ASESPGPGGLASLGKHRPKGFFATESSFDPHHRAQPSYERPSFLPPGPGLMLR 887
++ T++ ++SP P G+ S P + P+ + + GP +
Sbjct: 783 SKGTLTYLADSPSPLGV----------------SVSPQTKRPPTKKGSA----GPDTPIG 822
Query: 888 QKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIP-------PPPTTSPPEPPYSTPPVPS 940
S + + +L SLS GS+D P PP P P TP P
Sbjct: 823 NLSSPVSPVEASFLP------ENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPK 876
Query: 941 S-----SGRLTPSPRGGPF-NPGSGGPLPASSPA-SFDGPSPPDTRVGSREKSLYHS--- 990
TPS PF G P P +PA S SP R K + S
Sbjct: 877 GVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSP 936
Query: 991 --GPLPPAHHHPPHHHHHHAPPPQ--PHHHHAHPPHPPEMETGGSPDD-PPPRLALGPQP 1045
P PPA P P P+ P A PP P SP P P A P P
Sbjct: 937 KGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSP 996
Query: 1046 SLRGWRGGGPSPTP-GAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGR 1104
+GG +P+P GAP+P G + P + PP A P+ G
Sbjct: 997 -----KGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATP-----PSPKGS 1046
Query: 1105 GRKGPLVKQTKV---------EGEPQ----KGGGLPPAPSPTS----PASPQP-----PP 1142
PL K +G P KG PPA +P S PA+P P PP
Sbjct: 1047 PAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPP 1106
Query: 1143 AVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAP 1202
A PS K + P K T+ + A PP + PT + PSP
Sbjct: 1107 AATPPSPKGGLATPP--HKGAPTTPAATPPSPKGGLATPPPKGAPT---TPAATPPSPKG 1161
Query: 1203 AMSPVPPSPSPVPTPASPSGP-ATLDFTSQFGAALVGAA---RREGGWQNEARRRSTLFL 1258
++ PP +P A+P P L S GA AA +GG + + +
Sbjct: 1162 GLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP--- 1218
Query: 1259 STDAGDEDGGDGGLGTGA---APGPRLRHSKSIDEGMFSAEPY-LRLESAGSGAGYGGYG 1314
+T A GGL T + AP S G + P A + G G
Sbjct: 1219 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKG-G 1277
Query: 1315 AGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKESSEGGGAP 1374
+ + G + T PP P P T +P A S +G
Sbjct: 1278 LATPPHKGAPNPAVVT---PPSPKGGPATSPPKGAPTP--------PAATPPSPKGSPGT 1326
Query: 1375 QPPPRPPSPRYEAPP-----PTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQ 1429
PP P+P PP PT +P + P P PA
Sbjct: 1327 PPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAAT---------PS 1377
Query: 1430 EKSLPA-SPPAARRSLLHRLP---PTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEP 1485
K PA +PP+ +R P PT+P V PL + P G + P + P
Sbjct: 1378 HKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDL-TPP 1436
Query: 1486 ERLPLHVRFLENCQPRAPVTS----GRGPPSEDG----PGVPPPSPRRSVPPSP------ 1531
P+ ++ +AP TS G PS G P V PPSP+ PP+P
Sbjct: 1437 AVTPVSLK-------KAPATSAPKGGPATPSSKGDPTLPAVTPPSPKE--PPAPKQVATS 1487
Query: 1532 ----TSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSN-----SFEKPES 1582
+P G P L P+ +V +P+ P + + E+
Sbjct: 1488 SSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEA 1547
Query: 1583 PLTPGPPHPLP-DTPAPATP--LPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGAS 1639
+ P P P TPA TP P P A++PP + T S+ S L A
Sbjct: 1548 LIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAV--TPSTYKGAPSPKELLIPPAV 1605
Query: 1640 AAPGDPHPPGPPAPAAPAP------AAPQPGPDPPPGTDSGIEEVDSRSSSDHPLETISS 1693
+P P PPA P+P AP+ P PP T S +++ + +S T
Sbjct: 1606 TSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPAS----VTCKM 1661
Query: 1694 ASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVA-YLDGQAFGGSSTPGPPYPPQLM 1752
+T+ S G VA PE A G SS PP P
Sbjct: 1662 GATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPD-- 1719
Query: 1753 TPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAGVA 1812
PS G + G + P P+ P S T G D + + PP + A
Sbjct: 1720 -PSAKNG-SKGPLSTVAPA-------PLLPVQKDSSKTAKGKDASHSPKGPLAPPES-KA 1769
Query: 1813 GGPVAVEPEVPPVPLPTASSL-----PRKLLPWEEGPGPPPPP 1850
P+ +P P ++S+ P LP P P PP
Sbjct: 1770 STPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPP 1812
Score = 140 bits (352), Expect = 2e-32
Identities = 316/1298 (24%), Positives = 422/1298 (32%), Gaps = 260/1298 (20%)
Query: 924 PTTSPPEPPYSTPPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFD---GPSPPDTRV 980
PTT+ Y+T P G ++ +P+ P G+ LP AS + PSP +T
Sbjct: 660 PTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCA 719
Query: 981 GSREKSLYHSGP-------LPPAHHHPPHHH-----HHHAPPPQPHHHHAHPPHPPEMET 1028
L P LPPA P H A P P
Sbjct: 720 PLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASA 779
Query: 1029 GGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAG-----GGGGSSQGPALR 1083
S LA P P G SP P P+ GSAG G S P
Sbjct: 780 TASSKGTLTYLADSPSPL-----GVSVSPQTKRP-PTKKGSAGPDTPIGNLSSPVSPVEA 833
Query: 1084 YFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPA 1143
F LP + S + P + P KG P A +P SP PP
Sbjct: 834 SF-LPENSLSFQ--------GSKDSPATTHSPTPPSP-KGAPTPSAVTPLSPKGVTLPPK 883
Query: 1144 ---------VAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGG 1194
+ P E + P P TSSS + ++ + P P P G
Sbjct: 884 ETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPP 943
Query: 1195 GSSPSPAPAMSPVPPSPSPVPTPASPSGPATLDFTSQFGAALVGAARREGGWQNEARRRS 1254
++P P+P P PSP PTP + + P+ +GG + + +
Sbjct: 944 AATP-PSPKGGPATPSPKWAPTPPAATPPSP-----------------KGGPATPSPKGA 985
Query: 1255 TLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYG 1314
+ GG AP P S +G +A P+ +
Sbjct: 986 PTPPAATPPSPKGGPATPSPKGAPTPPAVTPPS-PKGSPAATPFPK-------------- 1030
Query: 1315 AGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKESSEGG--- 1371
G+S + PP P K A+PL A S +GG
Sbjct: 1031 ----------GASTPPAATPPSP-------KGSPAATPLPKGAPTTPAATLPSPKGGPAT 1073
Query: 1372 ----GAPQPPPR-PPSPRYEAPPPTPHHHS-PHAHHEPVLRLWGASPPD------PARRE 1419
GAP PP PPSP+ P+P P A P + A+PP PA
Sbjct: 1074 PSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATP 1133
Query: 1420 LGYRAGLGSQEK----SLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSK 1475
+ GL + + PA+ P + + L PP P PP+P G++
Sbjct: 1134 PSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTP-----AATPPSPKGGLAT 1188
Query: 1476 PWRSAAPEEPERLPLHVRF-LENCQPR-APVTSGRGPPSEDGPGVPPPSPR------RSV 1527
P AP P P + L P+ AP T PPS G G+ PSP+ +
Sbjct: 1189 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG-GLATPSPKGAPTTPAAT 1247
Query: 1528 PPSPTS-PRASEENGLPLLVLPPPAPSVDVEDGEFLFVEP---LPPPLEFSNSFEKPESP 1583
PPSP P G P PP A ++ G L P P P + K
Sbjct: 1248 PPSPKGGPATPPPKGAPT---PPAATPPSLKGG--LATPPHKGAPNPAVVTPPSPKGGPA 1302
Query: 1584 LTPGPPHPLPDTPAPATPL--PPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAA 1641
+P P P P +P P PPP A PP + + T ++G
Sbjct: 1303 TSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTT 1362
Query: 1642 PGDPHPPGPPAPA-------APAPAAPQPGPD-PPPGTDSGIEEVDSRSSSDHPLETIS- 1692
P P PPA A P +P+ GP P P D V S P ++
Sbjct: 1363 PSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTR 1422
Query: 1693 -------------SASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGG 1739
A T SL SA GG A P L A
Sbjct: 1423 EGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTL----------PAVTP 1472
Query: 1740 SSTPGPPYPPQLMT---PSKLRGRALGASGGLRPG--PSGGLRDPVTPTS------PTVS 1788
S PP P Q+ T P K P PS P TP+S PT +
Sbjct: 1473 PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTAT 1532
Query: 1789 VTGAGTDGLLALRACSGPPTAGV-----------------------AGGPVAVEPE---- 1821
+ T LA + PP V A P AV P
Sbjct: 1533 LLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKG 1592
Query: 1822 --------VPPV---PLPTASSLPRKLLP--WEEGPGPPPP---PLPGPLAQPQASALAT 1865
+PP P P + P + P E+GP P P P P+ T
Sbjct: 1593 APSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPT 1652
Query: 1866 VKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYVPERTS--SLQRQR 1923
AS+ ++ + + Q A LP +G + + PE T + ++
Sbjct: 1653 SPASVTCKMGATVPQ------ASKGLPAKKGPTA----LKEVLVAPAPESTPIITAPTRK 1702
Query: 1924 LSDDSQSSLLSKPV--SSLFQNWPKPPL------PPLPTGTGVSPTAAAAPGATSPS--- 1972
+SS S P+ +N K PL P LP S TA + SP
Sbjct: 1703 GPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPL 1762
Query: 1973 ASSSSTSTRHLQGVEFEMRPPLLRRAPSPSLLPASEHKVSPAPRPSSLPILPSG----PL 2028
A S ++ L FE +L + S S+ A VS PS +P LP P
Sbjct: 1763 APPESKASTPLTAAAFE---KVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPS 1819
Query: 2029 YPGLFDIRGSPTGG-AGGSADPFAPVFVPPHPGISGGL 2065
PGL + SP+ A D P+ +PP P ISGG+
Sbjct: 1820 SPGL--VLESPSKPLAPADEDELLPL-IPPEP-ISGGV 1853
Score = 109 bits (273), Expect = 3e-23
Identities = 269/1147 (23%), Positives = 374/1147 (32%), Gaps = 192/1147 (16%)
Query: 1018 AHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGG---- 1073
A P + P ++ S P + L P+ +L G P P G P+ S G
Sbjct: 565 AAPKNSPSFQSTSSS----PEIPLSPEATLAKKSLGEPLPI-GKPASSMTSPLGVNSSAS 619
Query: 1074 --------GGSSQGPALRYFQLPPRAASAAMYVPARSGRG---RKGPLVKQTKVEGEPQK 1122
G S GP L+ + P A+ + +G KG T +
Sbjct: 620 VIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEG 679
Query: 1123 GGGLPPAPSPTSPASPQPPPAV--------AAPSEKNSI-PIPTIIIKAPSTSSSGRSSQ 1173
L P P + P V APS +N+ P+ T+++ AP S S
Sbjct: 680 TVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVL-APEIPKSVPS-- 736
Query: 1174 GSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPSPVPTPASPSGPATLDFTSQFG 1233
P P T G S A++PV SP PT
Sbjct: 737 -------PSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPT----------------- 772
Query: 1234 AALVGAARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMF 1293
+ G A + TL D+ LG +P + +K G
Sbjct: 773 --------EDSGASATASSKGTLTYLADSPSP------LGVSVSPQTKRPPTKKGSAGPD 818
Query: 1294 SAEPYLRLESAGSGAGYGGYGAGSRAYGGGGGSSAFT-SFLPPRPLVHPLTGKALDPASP 1352
+ P L S S S ++ G S A T S PP P P T A+ P SP
Sbjct: 819 T--PIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAP-TPSAVTPLSP 875
Query: 1353 LGLALAARER------------------------ALKESS----EGGGAPQPPPRP--PS 1382
G+ L +E AL +S + P P P PS
Sbjct: 876 KGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPS 935
Query: 1383 PRYEAPPPTPHHHSPHAHHEPVLRLWGASPP--DPARRELGYRA----GLGSQEKSLPAS 1436
P+ PP SP W +PP P + G G + + P S
Sbjct: 936 PKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPS 995
Query: 1437 PPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHP-GVSKPWRSAAPEEPERLPLHVRFL 1495
P + + PT P V P + G+ P P G S P +A P P+ P
Sbjct: 996 PKGGPATPSPKGAPTPPAVTPPSPK-GSPAATPFPKGASTP-PAATPPSPKGSPAATPLP 1053
Query: 1496 ENCQPRAPVTSGRGPPS-EDGPGVP----PPSPRRSVPPSPT-SPRASEENGLPLLVLPP 1549
+ AP T PS + GP P P+P + PPSP P G P+ P
Sbjct: 1054 KG----APTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPM----P 1105
Query: 1550 PAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPA 1609
PA + G P + + P+ L PP P TPA PP P
Sbjct: 1106 PAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT---PPSPKGG 1162
Query: 1610 VAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAP----AAPAP-AAPQPG 1664
+A PP T + T + T AP P PP+P A P+P AP
Sbjct: 1163 LATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTP-AATPPSPKGGLATPSPKGAPTTP 1221
Query: 1665 PDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPEL 1724
PP G+ + + P T S +GG + GA A+ P
Sbjct: 1222 AATPPSPKGGLATPSPKGAPTTPAAT--------PPSPKGGPATPPPKGAPTPPAATPPS 1273
Query: 1725 LDTYVAYLDGQAFGGSSTP---GPPYPPQLMTPSKLRGRALGASGG-------LRPGPSG 1774
L GG +TP G P P + PS G A G P P G
Sbjct: 1274 LK-----------GGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKG 1322
Query: 1775 GLRDPVTPTSPT-VSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSL 1833
P +PT +VT G L A + P + G P + E PP P+
Sbjct: 1323 SPGTPPPKGAPTPPAVTPPSPKGTPTLPATT-PSSKGGPTTPSSKEGPTPPAATPSHKGG 1381
Query: 1834 PRKLLPW-EEGP------GPPPPPLPGPLAQPQASALATVKASIISELSSKLQQFGGSSA 1886
P P + GP G P P PL+ +A A + + L +
Sbjct: 1382 PAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPV 1441
Query: 1887 AGGALPWARGGSGGGGDSHHGGASYVPERTSSLQRQRLSDD---SQSSLLSKPVSSLFQN 1943
+ P GG G +P T ++ + + SS P +
Sbjct: 1442 SLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMG 1501
Query: 1944 WPKPP--LPPLPTGTGVSPTAAAAPGATSPSASSSSTSTRHLQGVEFEMRPPLLRRAPSP 2001
P P +P P +P++ P +P+A+ S T + + PP + PSP
Sbjct: 1502 APTLPAVIPSSPKEVPATPSSRRDP--IAPTATLLSKKTPATLAPKEALIPPAM-TVPSP 1558
Query: 2002 SLLPA----SEHKVSPAPRPSSLP--ILPS---GPLYPGLFDIRGSPTGGAGGSADPFAP 2052
PA E +P+ + +S P + PS G P I + T + A P P
Sbjct: 1559 KKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEA-PTPP 1617
Query: 2053 VFVPPHP 2059
PP P
Sbjct: 1618 AVTPPSP 1624
Score = 95.1 bits (235), Expect = 6e-19
Identities = 179/733 (24%), Positives = 238/733 (32%), Gaps = 126/733 (17%)
Query: 1432 SLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLH 1491
+LP P A+ P AP L T AP S P S P
Sbjct: 697 TLPLVPTASENC------PVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKK 750
Query: 1492 VRFLENCQPRAPVTSG-RGPPSEDGPGVPPPSPRRSVP-----PSPTSPRASEENGLPLL 1545
V + + APV S + P+ED S + ++ PSP S + P
Sbjct: 751 VDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPT 810
Query: 1546 VLPPPAPSVDVEDGEFLFVEPLPP---------PLEFSNSFEKPESPLTPGPPHPL-PDT 1595
P + + P+ P L F S + P + +P PP P T
Sbjct: 811 KKGSAGPDTPIGN----LSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPT 866
Query: 1596 PAPATPLPP---------VPPPAVA---------AAPPTLDSTASSLTSYDSEVATLTQG 1637
P+ TPL P P P+V A P + A S+TS + A T
Sbjct: 867 PSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPA 926
Query: 1638 ASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTL 1697
P P P G P P A P +P+ GP P + + P T
Sbjct: 927 PKGIPASPSPKGAPTPPAATPPSPKGGPATP----------SPKWAPTPPAAT------- 969
Query: 1698 SSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGP---PYPPQLMTP 1754
S +GG + GA A+ P GG +TP P P PP + P
Sbjct: 970 -PPSPKGGPATPSPKGAPTPPAATPP-----------SPKGGPATPSPKGAPTPPAVTPP 1017
Query: 1755 SKLRGRAL-----GAS---GGLRPGPSGG-LRDPV---TPTSPTVSV-TGAGTDGLLALR 1801
S A GAS P P G P+ PT+P ++ + G +L+
Sbjct: 1018 SPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLK 1077
Query: 1802 ACSGPPTA---GVAGGPVAVEPEVPPVPLPTASSLPRKLL--PWEEG----PGPPPPPLP 1852
PP A GGP P+ P+P P+ L P +G P PP
Sbjct: 1078 GAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPK 1137
Query: 1853 GPLAQPQASALATVKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYV 1912
G LA P T A+ L A GG GA
Sbjct: 1138 GGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1197
Query: 1913 PERTSSLQRQRLSDDSQSSLLSKPVSS-------LFQNWPK------PPLPPLPTGTGVS 1959
P T + L+ S + P ++ L PK PP P G +
Sbjct: 1198 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPAT 1257
Query: 1960 PT---AAAAPGATSPSASSSSTSTRHLQGVEFEMRPPLLRRAPSPSLLPA-SEHKVSPAP 2015
P A P AT PS + H P + PSP PA S K +P P
Sbjct: 1258 PPPKGAPTPPAATPPSLKGGLATPPHKGAPN-----PAVVTPPSPKGGPATSPPKGAPTP 1312
Query: 2016 RPSSLPILPSGPLYPGLFDIRGSPTGGAGGSADPFAPVFVPPHPGISGGLGGALSGASRS 2075
P++ P P G PG +G+PT A P +P P P + G + S
Sbjct: 1313 -PAATPPSPKGS--PGTPPPKGAPTPPA---VTPPSPKGTPTLPATTPSSKGGPTTPSSK 1366
Query: 2076 LSPTRLLSLPPDK 2088
PT + P K
Sbjct: 1367 EGPTPPAATPSHK 1379
Score = 68.6 bits (166), Expect = 7e-11
Identities = 167/705 (23%), Positives = 231/705 (32%), Gaps = 149/705 (21%)
Query: 1510 PPSEDGP--GVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPL 1567
PP GP + P SP V +P +P+ L +P P D ED ++ L
Sbjct: 465 PPMSSGPISNIEPTSPAALVM-APVAPKEPSTQVATTLRIPVSPPLPDPED-----LKNL 518
Query: 1568 PPPLEFSNSFEKPESPLTPGPPHPLPDTPAPA---TPLPPVPPPAVAAAP---PTLDSTA 1621
P + +K + P P +PA A T P P V AAP P+ ST+
Sbjct: 519 PSSVLVKFPTQK-DLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTS 577
Query: 1622 SSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAP-----AAPQPGPDPPPGTDSG-- 1674
SS S ATL A + G+P P G PA + +P +A D G DS
Sbjct: 578 SSPEIPLSPEATL---AKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGP 634
Query: 1675 ---------------IEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAG---------- 1709
+E D + + S+ +T +S EG S
Sbjct: 635 LLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGT 694
Query: 1710 -------GGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRAL 1762
VA P+ +A L S P P PP P + +
Sbjct: 695 LTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGI 754
Query: 1763 GASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLA-------------------LRAC 1803
+ L P S P + + + + GT LA +
Sbjct: 755 SHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGS 814
Query: 1804 SGPPT------------------------AGVAGGPVAVEPEVPPVP--LPTASSL---- 1833
+GP T G P PP P PT S++
Sbjct: 815 AGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLS 874
Query: 1834 PRKL-LPWEEGPGPPPPPLPGPLAQPQASALATVKASIISELSSKLQQFGGSSAAGGALP 1892
P+ + LP +E P P LP P P A A ++ S K + + A P
Sbjct: 875 PKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASP 934
Query: 1893 WARGG---SGGGGDSHHGGASYVPERTSSLQRQRLSDDSQSSLLSKPVSSLFQNWPKPP- 1948
+G S GG P S + S P + + P PP
Sbjct: 935 SPKGAPTPPAATPPSPKGG----PATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPA 990
Query: 1949 -LPPLPTGTGVSPT---AAAAPGATSPSASSSSTSTRHLQGVEF--EMRPPLLRRAPSPS 2002
PP P G +P+ A P T PS S +T +G PP + +P+ +
Sbjct: 991 ATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAAT 1050
Query: 2003 LLPASEHKVSPAPRPSSLPILPSGPLYPGLFDIRGSPTGGA-------GGSAD------P 2049
LP K +P ++LP GP P L +G+PT A GG A P
Sbjct: 1051 PLP----KGAPTTPAATLPSPKGGPATPSL---KGAPTPPAATPPSPKGGPATPSPKGAP 1103
Query: 2050 FAPVFVPPHPGISGGL------GGALSGASRSLSPTRLLSLPPDK 2088
P PP P GGL G + A+ SP L+ PP K
Sbjct: 1104 MPPAATPPSP--KGGLATPPHKGAPTTPAATPPSPKGGLATPPPK 1146
Score = 59.7 bits (143), Expect = 3e-08
Identities = 102/437 (23%), Positives = 143/437 (32%), Gaps = 64/437 (14%)
Query: 827 AAAQQTISASESPGPGGLASLGKHRPKGFFATESSFDPHHRAQPSYERPSFLPPGPGLML 886
A Q S+S P A +G + P A PS R P P L
Sbjct: 1480 APKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVP---ATPSSRRD---PIAPTATL 1533
Query: 887 RQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPVPSSSGRLT 946
K A + L PPAM P P T + S P V S+ +
Sbjct: 1534 LSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGA 1593
Query: 947 PSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHH 1006
PSP+ P +SP+ + P+PP S EK GP PA P
Sbjct: 1594 PSPKELLIPPA------VTSPSPKEAPTPPAVTPPSPEK-----GPATPAPKGTP----- 1637
Query: 1007 HAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLAL----GPQPSLRGWRGGGPSPTPGAP 1062
+PP P P P + P L GP P TP
Sbjct: 1638 TSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIIT 1697
Query: 1063 SPSHHGSAGGGGGSSQGP------ALRYFQLPPRAASAAMYVP-----ARSGRGR----- 1106
+P+ G ++ P A + P + A +P +++ +G+
Sbjct: 1698 APTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHS 1757
Query: 1107 -KGPLVKQTKVEGEPQKGGG----LPPAPSPTSPASPQPPPAV-AAPSEKNSIP------ 1154
KGPL P LP S + A+P PP ++ APS ++P
Sbjct: 1758 PKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFL 1817
Query: 1155 --IPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGS----SPSPAPAMSPVP 1208
P +++++PS + E P PEP GG S P+P A PVP
Sbjct: 1818 PSSPGLVLESPSKP----LAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVP 1873
Query: 1209 PSPSPVPTPASPSGPAT 1225
+ P + G T
Sbjct: 1874 TPSAKQPVTKNNKGSGT 1890
Score = 59.3 bits (142), Expect = 4e-08
Identities = 174/768 (22%), Positives = 261/768 (33%), Gaps = 163/768 (21%)
Query: 1450 PTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPL----HVRFLENCQPRAPVT 1505
P +P P L L T+ P V+ ++A P P P+ H+ L +
Sbjct: 269 PVSP---PAALSLSTQSL---PVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQL 322
Query: 1506 SGRGPPS-------------EDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAP 1552
G+ PS G PS R +PP P+ +E + P AP
Sbjct: 323 LGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSR---NEVVPATVAAFPVVAP 379
Query: 1553 SVDVEDGEFLFVEPLPP-PLEFSNSFE-KPESPL----TPGPPH------PLPDTPAPAT 1600
SVD + P L + SF P + L +P + +P + T
Sbjct: 380 SVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTT 439
Query: 1601 PLPPVPPPAVAAAPPTLDSTAS---------SLTSYDSEVATLTQGASAAPGDPH----- 1646
PL P +AAAP T A+ +++ + A AP +P
Sbjct: 440 PLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVAT 499
Query: 1647 ----PPGPPAP---------------------AAPAPAAPQPGPDPPPGT------DSGI 1675
P PP P PA+ + P P D +
Sbjct: 500 TLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTV 559
Query: 1676 EEVDSRSSSDHPLETISSASTLSSLSAEGGGSAGGGG-----GAGAGVASGPELLDTYVA 1730
+ + + P +S+S LS E + G G A + P +++ +
Sbjct: 560 LPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSAS 619
Query: 1731 YLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGAS-GGLRPGPSGGLRDPVTPTSP---- 1785
+ ++ G + GP L+TP+ A G+ P + G T SP
Sbjct: 620 VIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEG 679
Query: 1786 TVSV------TGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPT---ASSLPRK 1836
TVS+ GT L L PTA PVA P+ PL T A +P+
Sbjct: 680 TVSLAPKNHPVKEGTLTTLPL-----VPTAS-ENCPVAPSPQNTCAPLATLVLAPEIPKS 733
Query: 1837 LLPWEEGPGPPPP--------------------PLPGPLAQPQASALATVKASIISELSS 1876
+ P PP P P ASA A+ K + ++ L+
Sbjct: 734 VPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGT-LTYLAD 792
Query: 1877 KLQQFGGSSAAGGALPWARGGSGGGGDSHHGG---------ASYVPERTSSLQRQRLSDD 1927
G S + P + GS G D+ G AS++PE + S Q S D
Sbjct: 793 SPSPLGVSVSPQTKRPPTKKGS-AGPDTPIGNLSSPVSPVEASFLPENSLSFQG---SKD 848
Query: 1928 SQSSLLSKPVSSLFQNWPKPPLPP-LPTGTGVSPTAAAAPGATSPSASSSSTSTRHLQGV 1986
S ++ S P PP P PT + V+P + G T P + + S +L
Sbjct: 849 SPATTHS----------PTPPSPKGAPTPSAVTP--LSPKGVTLPPKETPTPSVVNLPFP 896
Query: 1987 EFEMRPPLLRRAPSPSLLPASEHKVSPAPRPSSLPILPS---GPLYPGLFDIRGSPTGGA 2043
+ P ++AP+ S+ +S K P P +P PS P P SP GG
Sbjct: 897 KEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAA--TPPSPKGGP 954
Query: 2044 GGSADPFAPVFVPPHPGISGGLGGALSGASRSLSPTRLLSLPPDKPFG 2091
+ +AP PP GG + + + +PT + PP G
Sbjct: 955 ATPSPKWAP--TPPAATPPSPKGGPATPSPKG-APTPPAATPPSPKGG 999
Score = 55.5 bits (132), Expect = 6e-07
Identities = 108/477 (22%), Positives = 163/477 (34%), Gaps = 91/477 (19%)
Query: 768 KKAPQ-QAKRLPPPTISLRSKSMTSELEEMEYEQQPAP----VPSMEKKR--TVYQMALN 820
KKAP A + P T S + + ++ PAP S KK T M
Sbjct: 1444 KKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAP 1503
Query: 821 KLDEILAAAQQTISASESPGPGGLAS----LGKHRPKGFFATESSFDPHHRAQPSYERPS 876
L ++ ++ + + A+ S +A L K P E+ P + P+
Sbjct: 1504 TLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPA 1563
Query: 877 FLPPGPGLMLRQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIP-PPPTTSP-----PE 930
P K A + +PPA+ S P +++ PP TSP P
Sbjct: 1564 IPTP--------KEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPT 1615
Query: 931 PPYSTPPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSLYHS 990
PP TPP P G TP+P+G P +P P + + D P+ P + ++ +
Sbjct: 1616 PPAVTPPSPEK-GPATPAPKGTPTSP------PVTPSSLKDSPTSPASVTCKMGATVPQA 1668
Query: 991 GPLPPAHHHPPHHHHHH-APPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRG 1049
PA P AP P+ P S PP + P PS +
Sbjct: 1669 SKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPP----ICPDPSAKN 1724
Query: 1050 WRGGGPS---PTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGR 1106
G S P P P G +S P L P + A+ + A + +
Sbjct: 1725 GSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPK---GPLAPPESKASTPLTAAAFE-K 1780
Query: 1107 KGPLVKQTKVEGEPQKGGGLPPAPSPTS---------PASP----QPPPAVAAPSEKNS- 1152
P + V P LP APSP P+SP + P AP++++
Sbjct: 1781 VLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDEL 1840
Query: 1153 -----------------------------IPIPTIIIKAPSTSSSGRSSQGSSTEAE 1180
IP+PT K P T ++++GS TE++
Sbjct: 1841 LPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVT----KNNKGSGTESD 1893
Score = 45.4 bits (106), Expect = 6e-04
Identities = 91/359 (25%), Positives = 121/359 (33%), Gaps = 63/359 (17%)
Query: 1337 PLVHPLTGKALDPASPLGLALAARERALKESSEGGGAPQPPP-RPPSPRYEAPPPTPHHH 1395
P V P T K L + A + KE AP PP PPSP E P TP
Sbjct: 1583 PAVTPSTYKGAPSPKELLIPPAVTSPSPKE------APTPPAVTPPSP--EKGPATPAPK 1634
Query: 1396 SPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPAS--PPAARRSLLHRLPPTAP 1453
SP PA A + K LPA P A + L+ P + P
Sbjct: 1635 GTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTP 1694
Query: 1454 GV------GPLLLQLG-TEPP-APHP----GVSKPWRSAAPEEPERLPLHVRFLENCQPR 1501
+ GP + T PP P P G P + AP LP+ + + +
Sbjct: 1695 IITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAP--LLPVQKDSSKTAKGK 1752
Query: 1502 APVTSGRGP--PSEDGPGVP--------------------PPSPRRSVP--PSPTSPRAS 1537
S +GP P E P PSP S+P PSP
Sbjct: 1753 DASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPP 1812
Query: 1538 EENGLP----LLVLPPPAPSVDVEDGEFLFV---EPLPPPLEFSNSFEKPESPLTPGPPH 1590
++ LP L++ P P ++ E L + EP+ + F + +P + G P
Sbjct: 1813 KQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPV 1872
Query: 1591 PLPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQG--ASAAPGDPHP 1647
P P P T + D + L DS AT Q A+AA D P
Sbjct: 1873 PTPSAKQPVT-----KNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEP 1926
Score = 42.7 bits (99), Expect = 0.004
Identities = 113/460 (24%), Positives = 162/460 (35%), Gaps = 90/460 (19%)
Query: 1613 APPTLDSTASSLTSYDSEVATLTQGAS----AAPGDPHPPGPPAPAAPAP------AAPQ 1662
A T+ +T L +E A L ++ AA G P P PP P +PAP AA Q
Sbjct: 5 ATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPP-PCSPAPQQCPLSAANQ 63
Query: 1663 PGPDPPPGTDSG----IEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGV 1718
P P P T + + S S + PL T A T L G A A
Sbjct: 64 ASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTF--LPNLIGPPISPAALALASP 121
Query: 1719 ASGPELLDT--YVAYLDGQAFGGSSTP-GPPYPPQLMTPSKLRGRALGASGGLRPGPSGG 1775
P L T A L A S +PP L+T A+ SG +
Sbjct: 122 MIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPP--SVAVAESGSVIT----- 174
Query: 1776 LRDPVTPTSPTVSVTGAGTDGLLALRACSGPPT-------------AGVAGGPVAVEPEV 1822
L P+ P+ P ++ ++ + + PP A + G ++
Sbjct: 175 LSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTT 234
Query: 1823 PPVPLPTASSLPR-----KLLPWEEGPGPPPPPLPGPLAQPQASALATVKASIISELSSK 1877
P L AS + +L + PG L GP++ P A +L+T +++
Sbjct: 235 PTTTLAIASPQVKDTTISSVLISPQNPGSLS--LKGPVSPPAALSLSTQSLPVVTS---- 288
Query: 1878 LQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQRQRLSDDSQSSLLSKPV 1937
AG P S G SH P SS +L + S LS P
Sbjct: 289 -----SQKTAGPNTPPDFPISLG---SH-----LAPLHQSSFGSVQLLGQTGPSALSDPT 335
Query: 1938 --------SSLFQNWP--KPPLPPLPTGTGVSPTAAAAPGATSPSASSSSTSTRHLQGVE 1987
SS ++P + +PPLP+ V P AA +PS ++
Sbjct: 336 VKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISS----- 390
Query: 1988 FEMRPPLLRRAPSPSLLPASEHKVSPAPRPSSLPILPSGP 2027
+ +PS SL A+ +SP +SL IL S P
Sbjct: 391 -------ITCSPSGSLNVATSFSLSPT---TSL-ILKSSP 419
Score = 39.7 bits (91), Expect = 0.032
Identities = 125/569 (21%), Positives = 197/569 (34%), Gaps = 72/569 (12%)
Query: 1518 VPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVED--GEFLFVEPLPPPLEF-S 1574
+P P +V P ++ + G P LPPP + P P P S
Sbjct: 16 LPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIAS 75
Query: 1575 NSFEKPESPLTPGPPHPLPDTPAPATPL-----PPVPPPAVAAAPPTLDSTASSLTSYDS 1629
E P + G PL P T L PP+ P A+A A P +
Sbjct: 76 TPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMI------------ 123
Query: 1630 EVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPG-----TDSGIEEVDSRSSS 1684
A G P P A A AP + Q PP + E S +
Sbjct: 124 --------APTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITL 175
Query: 1685 DHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPG 1744
P+ + L+ + +E + G V++ P T +A + G +S P
Sbjct: 176 SAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQS---GVASLPQ 232
Query: 1745 PPYPPQLMTPSKLRGRALGASGGLRPGPSG--GLRDPVTPTSPTVSVTGAGTDGLLALRA 1802
L S +S + P G L+ PV+P + +S++ + + +
Sbjct: 233 TTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPA-ALSLSTQSLPVVTSSQK 291
Query: 1803 CSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLAQPQASA 1862
+GP T P+++ + P+ SS L + GP P ++ +S
Sbjct: 292 TAGPNTP--PDFPISLGSHLAPL---HQSSFGSVQLLGQTGPSALSDPTVKTISVDHSST 346
Query: 1863 LATV--KASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQ 1920
A+ + S+I L S+ + + AA + S G S + P + ++
Sbjct: 347 GASYPSQRSVIPPLPSRNEVVPATVAAFPVV----APSVDKGPSTISSITCSPSGSLNVA 402
Query: 1921 RQRLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGVSP-------TAAAAPGAT---- 1969
S +SL+ K + ++P P+ + G +P T AAAP T
Sbjct: 403 TS-FSLSPTTSLILKSSPNATYHYPLVAQMPV-SSVGTTPLVVTNPCTIAAAPTTTFEVA 460
Query: 1970 ---SPSASSSSTSTRHLQGVEFEMRPPLLRRAPSPSLLPASEHKVS-PAPRPSSLPILPS 2025
SP SS S + P+ + PS + VS P P P L LPS
Sbjct: 461 TCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPS 520
Query: 2026 GPL--YPGLFDIRGSPTGGAGGSADPFAP 2052
L +P D++ P G PF+P
Sbjct: 521 SVLVKFPTQKDLQTVPASLEGA---PFSP 546
Score = 39.3 bits (90), Expect = 0.042
Identities = 83/367 (22%), Positives = 116/367 (31%), Gaps = 60/367 (16%)
Query: 899 PYLAPPAMKFSRSLSVPGSEDIPPPPTTSP-PEPPYSTPPVPSSSGRLTP---SPRGGPF 954
P L PP + + + P P+ S P P SSSG P +P F
Sbjct: 43 PTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTF 102
Query: 955 NPGSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPH 1014
P GP + + + P T G+ S PL P A PP
Sbjct: 103 LPNLIGPPISPAALALASPMIAPTLKGTPSSS----APLALVALAPHSVQKSSAFPP--- 155
Query: 1015 HHHAHPPHPPEMETGG--------SPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSH 1066
+ PP E+G +P +P L P + +G P + P H
Sbjct: 156 NLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYH 215
Query: 1067 HGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEG---EPQKG 1123
+ S LP + + + + P VK T + PQ
Sbjct: 216 CVTPMASIQSGVA------SLPQTTPTTTLAIAS--------PQVKDTTISSVLISPQNP 261
Query: 1124 GGL----PPAPSPTSPASPQPPPAV------AAPSEKNSIPIPTIIIKAPSTSSSGRSSQ 1173
G L P +P S Q P V A P+ PI AP SS S Q
Sbjct: 262 GSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQ 321
Query: 1174 -----GSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPP---------SPSPVPTPAS 1219
G S ++P + G S PS + P+P + PV P+
Sbjct: 322 LLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSV 381
Query: 1220 PSGPATL 1226
GP+T+
Sbjct: 382 DKGPSTI 388
Score = 34.3 bits (77), Expect = 1.4
Identities = 37/142 (26%), Positives = 50/142 (35%), Gaps = 22/142 (15%)
Query: 409 PFQESPKYAARR--------RGPPGT----GLTVPPALLRANSDTSMALPDWMVFSAPGA 456
P SPK+A +G P T G PPA + A P P A
Sbjct: 954 PATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPA 1013
Query: 457 AS----SGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARAR------SPSRGRHP 506
+ G+P T +G S P A T G+ + P+GA SP G
Sbjct: 1014 VTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPAT 1073
Query: 507 EDAKRQPRGRPSSSGTPREGPA 528
K P ++ +P+ GPA
Sbjct: 1074 PSLKGAPTPPAATPPSPKGGPA 1095
Score = 34.3 bits (77), Expect = 1.4
Identities = 35/138 (25%), Positives = 51/138 (36%), Gaps = 14/138 (10%)
Query: 402 HREQDVVPFQESPKYAARRRGPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGA 461
H+ P P PP G PA + +A P AP ++
Sbjct: 1122 HKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPK--GAPTTPAATP 1179
Query: 462 PGPTSGSQGQSQPSAPTTKLSS-----GTLRSASSPRGARARSPSRGRHPED--AKRQPR 514
P P G S APTT ++ G L + SP+GA + P+ A P+
Sbjct: 1180 PSPKGGLATPSPKGAPTTPAATPPSPKGGL-ATPSPKGAPTTPAATPPSPKGGLATPSPK 1238
Query: 515 GRPSSSG----TPREGPA 528
G P++ +P+ GPA
Sbjct: 1239 GAPTTPAATPPSPKGGPA 1256
Score = 33.9 bits (76), Expect = 1.8
Identities = 31/103 (30%), Positives = 44/103 (42%), Gaps = 14/103 (13%)
Query: 1121 QKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSS---- 1176
Q G LPP P SPA Q P ++A ++ + P P+ I P +SS G++
Sbjct: 40 QPGPTLPP---PCSPAPQQCP--LSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLG 94
Query: 1177 TEAEPPT-----QPEPTGGGGGGGSSPSPAPAMSPVPPSPSPV 1214
T E PT P +SP AP + P S +P+
Sbjct: 95 TAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPL 137
Score = 33.9 bits (76), Expect = 1.8
Identities = 31/116 (26%), Positives = 44/116 (37%), Gaps = 8/116 (6%)
Query: 423 PPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQSQPSAPTTKLS 482
PP G PPA+ + + LP A +S G P S +G + P+A +
Sbjct: 1327 PPPKGAPTPPAVTPPSPKGTPTLP------ATTPSSKGGPTTPSSKEGPTPPAATPSHKG 1380
Query: 483 SGTLRSASSPRGARARSPSRG-RHPEDAKRQPRGRPSSSGTPREGPAGGTGGSGGP 537
+ S RG SP P P+ P++ T REG A + G P
Sbjct: 1381 GPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVT-REGAATPSKGDLTP 1435
Score = 32.7 bits (73), Expect = 4.0
Identities = 22/81 (27%), Positives = 32/81 (39%), Gaps = 3/81 (3%)
Query: 1147 PSEKNSIPIP---TIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPA 1203
P+ + +P P T ++ S S + PP P P + SP P+
Sbjct: 10 PATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPS 69
Query: 1204 MSPVPPSPSPVPTPASPSGPA 1224
S + +P VP P S SG A
Sbjct: 70 PSTIASTPLEVPFPQSSSGTA 90
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 143 bits (361), Expect = 2e-33
Identities = 276/1115 (24%), Positives = 374/1115 (33%), Gaps = 158/1115 (14%)
Query: 899 PYLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPVPSSS-------------GRL 945
P PPA R P +++ P P +SP +T P P G+
Sbjct: 90 PASRPPAS--GRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKA 147
Query: 946 TPSPRGGPFNPGS----GGPLPAS-SPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHP 1000
T +P+ + G+ GP P + SPA T VG P P A P
Sbjct: 148 TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR-------PAPSARPRP 200
Query: 1001 PHHHHHHAPPPQPHHHHAHPPHPPEME--TGGSPDDPPPRLALGPQPSLRGWRGGGPSPT 1058
P + H P GG P R L GPS
Sbjct: 201 PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSAR 260
Query: 1059 PGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEG 1118
+P+H G ALR Q+ P AA PA GPL
Sbjct: 261 GTPRAPAHPSQPKPKGLQ----ALRPPQVTPPRKDAA---PAL------GPLSSSPLATP 307
Query: 1119 EPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTE 1178
P G P P P + A+P P A PS + P+P + PS S+ S
Sbjct: 308 SPS-GTKARPVPPPDNAATPLP--ATLPPSPPLATPLP---LAPPSPSAPPSLQTLPSPP 361
Query: 1179 AEPPTQPEPTGGGGGGGSSPSPAP-AMSPVPPSPSP-------VPTPASPSGPATLDFTS 1230
A PP+Q P+ + P AP ++ +PP P + P SP ++L T+
Sbjct: 362 ATPPSQAPPSMT-----TPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATT 416
Query: 1231 QFGAALVGAARR---EGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKS 1287
G+ + A Q +A S ++ D L A+P + S +
Sbjct: 417 SLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPA 476
Query: 1288 ID--EGMFSAEPYLRLESAGSGAGYGGYGAGSRAYGGGGGSSAFTSF-LPPRPLVHPLTG 1344
+ + P L S S + + S A S PP L P
Sbjct: 477 VSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLE 536
Query: 1345 KALDPASPLGLALAARERALKESSEGGGAPQPPPRPPSPRYEAPPPTPHH-HSPHAHHEP 1403
A P +A + AP P PPSP PP TP +P P
Sbjct: 537 NLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPP 596
Query: 1404 VLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAARRSLLHRLP---PTAPGVGPLLL 1460
L ASPP GL S S A+PP L P P +P P L
Sbjct: 597 AL----ASPP---------LQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLS 643
Query: 1461 QLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPP 1520
L T P ++ A P P+ F P PV+ PPS+ P +
Sbjct: 644 PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP--PVSPSATPPSQAPPSLA- 700
Query: 1521 PSPRRSVPPSPTSPRASEENGLPLLVLPPP--APSVDVEDGEFLFVEPLPPPLEFSNSFE 1578
+P VPPSP + + P PPP AP + V P PP+ S +
Sbjct: 701 -APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP-----PASPPMSPSATPP 754
Query: 1579 KPESPLTPGPPHPLPDTPAPATPLPPV--PPPAV--AAAPPTLDSTASSLTSYDSEV--- 1631
PL PP +P +P + P+ P+ PPP A A P L + S S+ +
Sbjct: 755 PRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS 814
Query: 1632 --ATLTQGASAAPGDPHPP---------GPPAPAAPAPAAPQPGPDPPPGTD-SGIEEVD 1679
A+L A P PP P PA+P AP+ P P P T SG
Sbjct: 815 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL 874
Query: 1680 SRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGG 1739
+ + P + S +STLS G S+ S PE L Y + +G G
Sbjct: 875 ALAPGPPPPPSRSPSSTLSGPDLAGHSSSA---------TSTPEELRGYDSGPEG---GA 922
Query: 1740 SSTPGPPYPPQLMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGT-DGLL 1798
+++P P P A+ P P R P TG G+ DGL
Sbjct: 923 AASPPPDAELAACHP---------AAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLC 973
Query: 1799 ALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLAQP 1858
+ GP +A A G + P P P S G G A+
Sbjct: 974 TIYETEGPESATPAPGAL------DPGPSPGTSGGKAAA-----GAGAGASSRSPKQARL 1022
Query: 1859 QASALATVKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYV------ 1912
L ++AS++ L S+ + A G GG+ GGG + GGA
Sbjct: 1023 GELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVT--GGARAALSDAEL 1080
Query: 1913 ---PERTSSLQRQRLSDDSQSSLLSKPVSSLFQNW 1944
E S L R S S +S V+S +W
Sbjct: 1081 GRWAELLSPLDESRASITSVTSFSPDDVASPQGDW 1115
Score = 129 bits (325), Expect = 2e-29
Identities = 310/1218 (25%), Positives = 400/1218 (32%), Gaps = 259/1218 (21%)
Query: 1021 PHPPEMETGGSPDDPPPRL-----------ALGPQPSLRGWRGGGPSPTPGAPSPSHHGS 1069
P PP GSP PPP A+G +P R GG S G
Sbjct: 27 PRPP-----GSPRPPPPVTPAALRVLGAAGAVGRKPLAE--RAGGIGGATIPESAPRAGP 79
Query: 1070 AGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTK---VEGEPQKGGGL 1126
G SS+ PA R P SGRG + P K T V + G
Sbjct: 80 TRSAGTSSRNPASR---------------PPASGRGERAPPAKNTSPGPVSSPGRASGTT 124
Query: 1127 PPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEP-PTQP 1185
P P VA T K + S+ R T P P
Sbjct: 125 RPGPLGQKGLRISAEETVARGKA-------TEAPKRSALSAGARRDTSGPTPGTPSPAMA 177
Query: 1186 EPTGGGGGGGSSPSPAPAMSPVPPSPSPVPTPASPSGPATLDFTSQFGAALVGAARRE-- 1243
+ G P PAP+ P PP+ P + +S S +T + + AARR
Sbjct: 178 RRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSP--------AARRRPS 229
Query: 1244 --GGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEP-YLR 1300
GG Q A R + + + G GT AP S+ +G+ + P +
Sbjct: 230 AGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPA---HPSQPKPKGLQALRPPQVT 286
Query: 1301 LESAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAAR 1360
+ G + A G+ A PP PL L P+ PL L
Sbjct: 287 PPRKDAAPALGPLSSSPLATPSPSGTKA-RPVPPPDNAATPLPA-TLPPSPPLATPLPLA 344
Query: 1361 ERALKESSEGGGAPQPPPRPPS--------PRYEAPPPT---PHHHSPHAHHEPVLRLWG 1409
+ P PP PPS P +APP P PH+ P L+
Sbjct: 345 PPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQ--- 401
Query: 1410 ASPPDP-ARRELGYRAGLGSQ-----EKSLPASPPAARRSLLHRLPP--TAPGVGPLL-- 1459
+PP P A L LGS L SP + SL P T P PL
Sbjct: 402 -APPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAP 460
Query: 1460 LQLGTEPPAP---HPGVSKPWRSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGP 1516
L L PP P VS P S P + + L + P+AP++S PP E
Sbjct: 461 LSLPASPPLQTSLSPAVS-PLSSPLTIHPLQA---LSSLASHSPQAPLSSLIMPPLETQS 516
Query: 1517 GVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNS 1576
+ PPS ++ P S T+P LP L PP + L P P P
Sbjct: 517 SLAPPS-LQTPPASLTTPPLEN---LPSLAPPPLQTASAPLTTPHLETPPCPAPCPL--- 569
Query: 1577 FEKPESPLTPGPPH-------------------PLPDTPAP-----ATPLPPVPP----- 1607
+ P SPLT PP PL P+P ATP P PP
Sbjct: 570 -QAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALP 628
Query: 1608 -----PAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPP--APAAPAPAA 1660
P+ A+PP S + ++ L Q AP P PP PP AP +P PA+
Sbjct: 629 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ----APFSP-PPSPPVQAPFSP-PAS 682
Query: 1661 PQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVAS 1720
P P P + + S + PL+ S +S SA A +A+
Sbjct: 683 PPVSPSATPPSQA------PPSLAAPPLQVPPSPPASPPMSP----SATPPPQAPPPLAA 732
Query: 1721 GPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTP--------------SKLRGRALGASG 1766
P L + S+TP P PP L P S L A
Sbjct: 733 PP--LQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPP 790
Query: 1767 GLRPGPSGGLRDP------VTPTSPTVSVTGA-------GTDGLLALRACSGPPTAGVAG 1813
L P L P P SP+ S+ + +LA PP+
Sbjct: 791 ALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP--PA 848
Query: 1814 GPVAVEPEVPPVPLP-TASSLPRKLLPWEEGPGPPPPPLPGPLAQPQASALATVKASIIS 1872
P P PP P P T+ S PR L PGPPPPP P + LA
Sbjct: 849 SPTLQAPRRPPTPGPDTSVSGPRLTLAL--APGPPPPPSRSPSSTLSGPDLA-------- 898
Query: 1873 ELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQRQRLSDDSQSSL 1932
G SS+A RG G GGA+ P + L
Sbjct: 899 ---------GHSSSATSTPEELRGYDSG----PEGGAAASPPPDAEL------------A 933
Query: 1933 LSKPVSSLFQNWPKPPLPPLPTGTGVSPTAAAAPGATSPSASSSSTSTRHLQGVEFEM-R 1991
P + W + P PPL G P AT P ++ + +G E
Sbjct: 934 ACHPAA-----WSRGPAPPL-AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPA 987
Query: 1992 PPLLRRAPSP------SLLPASEHKVSPAPRPSSLPILPSGPLYPGLFD-------IRGS 2038
P L PSP + A S +P+ + L LP G L + + +
Sbjct: 988 PGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAA 1047
Query: 2039 PTGGAGGSADPFAPVFVPPHPGISGGLGGALSGA-----SRSLSP--------TRLLSLP 2085
G AGGS G++GG ALS A + LSP T + S
Sbjct: 1048 AEGAAGGSGGGPGGA---EGGGVTGGARAALSDAELGRWAELLSPLDESRASITSVTSFS 1104
Query: 2086 PDKPFGAKPLGFWTKFDV 2103
PD A P G WT +V
Sbjct: 1105 PDDV--ASPQGDWTVVEV 1120
Score = 120 bits (302), Expect = 1e-26
Identities = 272/1079 (25%), Positives = 368/1079 (34%), Gaps = 194/1079 (17%)
Query: 1127 PPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPE 1186
P +P P SP+PPP V P+ + + + P +G G +T E +
Sbjct: 22 PGLLTPRPPGSPRPPPPV-TPAALRVLGAAGAVGRKPLAERAG--GIGGATIPESAPRAG 78
Query: 1187 PTGGGGGGGSSPSPAPAMS----PVPP----SPSPVPTPASPSGPATLDFTSQFGAALVG 1238
PT G +P+ P S PP SP PV +P SG Q G +
Sbjct: 79 PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 138
Query: 1239 AARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPY 1298
G EA +RS LS A + G T P P +
Sbjct: 139 EETVARGKATEAPKRSA--LSAGARRDTSGP----TPGTPSPAMAR-------------- 178
Query: 1299 LRLESAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGLALA 1358
R +AG+ G +R G S P P++ GL
Sbjct: 179 -RSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL--- 234
Query: 1359 ARERALKESSEGGGAPQPPPRPPSPRYEAPPPTPHHHS-PHAHHEPVLRLWGASPPDPAR 1417
+R S P P P P P H S P LR +PP R
Sbjct: 235 --QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP---R 289
Query: 1418 RELGYRAGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPW 1477
++ G S S P + P+ + +PP PL L PP P P
Sbjct: 290 KDAAPALGPLS---SSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPP 346
Query: 1478 RSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGPG---VPP-------PSPRRSV 1527
+AP + LP + P + T PP + P +PP SP
Sbjct: 347 SPSAPPSLQTLPSPPATPPSQAPPSMTT----PPMQAPPSLQTIPPIQVPHSLTSPSLQA 402
Query: 1528 PPSP---TSPRASEENGLPLL-----------------VLPPPAPSVDVEDGEFLFVE-- 1565
PPSP +S +A+ G P L + P P+ D L
Sbjct: 403 PPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLS 462
Query: 1566 -PLPPPLE--FSNSFEKPESPLTPGPPHPL-------PDTPAPATPLPPVPPPAVAAAPP 1615
P PPL+ S + SPLT P L P P + +PP+ + + APP
Sbjct: 463 LPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQS-SLAPP 521
Query: 1616 TLDSTASSLT-----SYDSEVATLTQGASAAPGDPHPPGPPAPA-APAPAAPQPGPDPPP 1669
+L + +SLT + S Q ASA PH PP PA P A P P PPP
Sbjct: 522 SLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPP 581
Query: 1670 GTDSGIEEVDSRSS---SDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLD 1726
T S I ++ + PL+ + S LS L A+ P
Sbjct: 582 ETPSSIATPPPQAPPALASPPLQGLPS-PPLSPL------------------ATPPPQAP 622
Query: 1727 TYVAYLDGQAFGGSSTPGPPYPP---QLMTPSKLRGRALGA---SGGLRPGPSGGLRDPV 1780
+A QA P PP P L TPS AL P PS ++ P
Sbjct: 623 PXLALPPLQA-----PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 677
Query: 1781 T-PTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLP 1839
+ P SP VS + T A + + PP V P A P P P + P P
Sbjct: 678 SPPASPPVS--PSATPPSQAPPSLAAPPLQ-VPPSPPASPPMSPSATPPPQAPPPLAAPP 734
Query: 1840 WEEGPGP-----------PPPPLPGPLAQPQASALATVKASI-ISELSSKLQQFGGSSAA 1887
+ P P PPP +P LA P + AS+ +S L+ Q + A
Sbjct: 735 LQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALAT 794
Query: 1888 GGALPWARGGSGGGGDSHHGGASYVPERTSSLQRQRLSDDSQSSLL----SKPVSSLFQN 1943
+ G + ++ +P + + + LL S P S Q
Sbjct: 795 PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 854
Query: 1944 WPKPPLP-PLPTGTGVSPTAAAAPG-----ATSPSA----------SSSSTST-RHLQGV 1986
+PP P P + +G T A APG + SPS+ SSS+TST L+G
Sbjct: 855 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY 914
Query: 1987 EFEMRPPLLRRAPSPSLLPASEHKV---SPAPRPSSLPILPSGPL------YPG------ 2031
+ P + L A PAP P + P PL PG
Sbjct: 915 DSGPEGGAAASPPPDAELAACHPAAWSRGPAP-PLAFRGAPGAPLPWPPATGPGSADGLC 973
Query: 2032 -LFDIRGSPTG-GAGGSADPFAPVFVPPHPGISGGLGGALSGA---SRSLSPTRLLSLP 2085
+++ G + A G+ DP P PG SGG A +GA SRS RL LP
Sbjct: 974 TIYETEGPESATPAPGALDP------GPSPGTSGGKAAAGAGAGASSRSPKQARLGELP 1026
Score = 91.7 bits (226), Expect = 7e-18
Identities = 142/557 (25%), Positives = 194/557 (34%), Gaps = 71/557 (12%)
Query: 844 LASLGKHRPKGFFATESSFDPHHRAQPSYERPSFLPPGPGLMLRQKSIGAAEDDRPYLAP 903
L+SL H P+ S P Q S PS P L ++ P LAP
Sbjct: 492 LSSLASHSPQA--PLSSLIMPPLETQSSLAPPSLQTPPASLTTPPL------ENLPSLAP 543
Query: 904 PAMKFSRSLSVPGSEDIPPPPTTSP---PEPPYSTPPVPSSSGRLTPSPRGGP---FNPG 957
P ++ + + + PP P P P P +TPP + S TP P+ P P
Sbjct: 544 PPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPL 603
Query: 958 SGGPLPASSPASFDGP-SPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHH 1016
G P P SP + P +PP + + + P PPA PP P P+
Sbjct: 604 QGLPSPPLSPLATPPPQAPPXLALPPLQ-----APPSPPA--SPPLSPLATPSPQAPNAL 656
Query: 1017 HAH--------PPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAP--SPSH 1066
H PP PP P PP + P P P +P SP
Sbjct: 657 AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM 716
Query: 1067 HGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGL 1126
SA + A Q+PP ++ P+ + R PL+ ++ P L
Sbjct: 717 SPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASL 776
Query: 1127 PPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRS--SQGSSTEAEPPTQ 1184
P +P P PQ PPA+A P P + +P S G++ S +S P
Sbjct: 777 PMSPLAKPP--PQAPPALATP--------PLQALPSPPASFPGQAPFSPSASLPMSPLAT 826
Query: 1185 PEPTGGGGGGGSSPSPAPAMSPVPPSPSPVPTPASPSGPATLDFTSQFGAALVGAARREG 1244
P P + P A + VPPSP PT +P P T + + A G
Sbjct: 827 PPPQ-------APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 879
Query: 1245 GWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLE-S 1303
+R S ST +G + G T LR S EG +A P E +
Sbjct: 880 PPPPPSRSPS----STLSGPDLAGHSSSATSTP--EELRGYDSGPEGGAAASPPPDAELA 933
Query: 1304 AGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERA 1363
A A + A A+ G G+ PL P A P S GL
Sbjct: 934 ACHPAAWSRGPAPPLAFRGAPGA----------PLPWP---PATGPGSADGLCTIYETEG 980
Query: 1364 LKESSEGGGAPQPPPRP 1380
+ ++ GA P P P
Sbjct: 981 PESATPAPGALDPGPSP 997
Score = 72.4 bits (176), Expect = 5e-12
Identities = 142/563 (25%), Positives = 193/563 (34%), Gaps = 58/563 (10%)
Query: 1495 LENCQPRAPVTSGRGPPSEDGPGV----PPPSPRRSVPPSPTSPRASEENGLPLLVLPPP 1550
++N + +A + P+ PG+ PP SPR PP P +P A G V P
Sbjct: 1 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPR---PPPPVTPAALRVLGAAGAVGRKP 57
Query: 1551 APSVDVEDGEFLFVEPLP---PPLEFSNSFEKPES-PLTPGPPHPLPDTPAPATPLPPVP 1606
G E P P S P S P G P PA T PV
Sbjct: 58 LAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAP--PAKNTSPGPVS 115
Query: 1607 PPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAP-------GDPHPPGPPAPAAPAPA 1659
P A+ +E A+ AP G P P P+PA
Sbjct: 116 SPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPA 175
Query: 1660 APQPGPDPPPGTDSGIEE----VDSRSSSDHPLETISSAS----TLSSLSAEGGGSAGGG 1711
+ GT+ G+ R ++ P +++SSAS T S +A SAGGG
Sbjct: 176 MARRSR--AAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG 233
Query: 1712 GGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPG 1771
A + L + L A G S G P P PS+ + + L A LRP
Sbjct: 234 LQRPASRS-----LSSSATPLSSPARSGPSARGTPRAPA--HPSQPKPKGLQA---LRPP 283
Query: 1772 PSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPV--PLPT 1829
R P +S + T +A PP A A P PP+ PLP
Sbjct: 284 QVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPL 343
Query: 1830 ASSLPRKLLPWEEGPGPP-------PPPLPGPLAQPQASALATVKASIISELSSKLQQFG 1882
A P + P PP PP + P Q S + L+S Q
Sbjct: 344 APPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAP 403
Query: 1883 GSSAAGGALPWARGGSGGGGDSHHGGASYVPERT----SSLQRQRLSDDSQSSL---LSK 1935
S A +L + H + P +T +S R + L LS
Sbjct: 404 PSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSL 463
Query: 1936 PVSSLFQNWPKPPLPPLPTGTGVSPTAAAAPGAT-SPSASSSSTSTRHLQGVEFEMRPPL 1994
P S Q P + PL + + P A + A+ SP A SS L+ + + PP
Sbjct: 464 PASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLE-TQSSLAPPS 522
Query: 1995 LRRAPSPSLLPASEHKVSPAPRP 2017
L+ P+ P E+ S AP P
Sbjct: 523 LQTPPASLTTPPLENLPSLAPPP 545
Score = 70.5 bits (171), Expect = 2e-11
Identities = 108/414 (26%), Positives = 138/414 (33%), Gaps = 96/414 (23%)
Query: 852 PKGFFATESSFDPHHRAQPSYERPSFLPPGPGLMLRQKSIGAAEDDRPYLAPPAMKFSRS 911
P AT S P+ A + P PP P + S A+ P PP+ S
Sbjct: 641 PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA-PFSPPASPPVSPSATPPSQA-PPS 698
Query: 912 LSVPGSEDIPPPPTTSPP------EPPYSTPPVPSSSGRLTPSPRGG-PFNPGSGGP--- 961
L+ P + +PP P SPP PP + PP+ + ++ PSP P +P + P
Sbjct: 699 LAAPPLQ-VPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV 757
Query: 962 ----------LPASSPASFDG----------------------PSPPDTRVGSREKSLYH 989
+P S PAS PSPP + G S
Sbjct: 758 PPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 817
Query: 990 SGPLPPAHHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPP----------PRL 1039
S P+ P PP APP PP PP T +P PP PRL
Sbjct: 818 SLPMSPLATPPP-----QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL 872
Query: 1040 ALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGG-----GGSSQGPALRYFQLPPRAASA 1094
L P PS T P + H S+ G GP PP A
Sbjct: 873 TLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL 932
Query: 1095 AMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPAS-PQPPPAVAAPSE---- 1149
A PA RG PL + G P AP P PA+ P + E
Sbjct: 933 AACHPAAWSRGPAPPLAFR-----------GAPGAPLPWPPATGPGSADGLCTIYETEGP 981
Query: 1150 KNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPA 1203
+++ P P + PS +SG + G G G SS SP A
Sbjct: 982 ESATPAPGALDPGPSPGTSGGKA---------------AAGAGAGASSRSPKQA 1020
Score = 65.1 bits (157), Expect = 7e-10
Identities = 116/471 (24%), Positives = 163/471 (34%), Gaps = 76/471 (16%)
Query: 778 PPPTISLRSKSMTSELEEMEYEQQPAPVPSMEKKRTVYQMALNKLDEILAAAQQTISASE 837
P P ++ RS++ +E+ P P E R A + + + +A
Sbjct: 172 PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEH-----STTEPSPAARR 226
Query: 838 SPGPGGLASLGKHRPKGFFATESSFDPHHRAQPSYERPSF--LPPGPGLMLRQKSIGAAE 895
P GG G RP + SS P + P+ PS P P + K G
Sbjct: 227 RPSAGG----GLQRPASR-SLSSSATP--LSSPARSGPSARGTPRAPAHPSQPKPKGLQA 279
Query: 896 DDRPYLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPVPSSSGRLTPSPRGGPFN 955
P + PP R + P + P +P PVP TP P P +
Sbjct: 280 LRPPQVTPP-----RKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPS 334
Query: 956 PGSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHH 1015
P PLP + P+ PS P + + P PPA PP Q
Sbjct: 335 PPLATPLPLAPPS----PSAPPS---------LQTLPSPPA-----------TPPSQAPP 370
Query: 1016 HHAHPP--HPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGG 1073
PP PP ++T P P L PSL+ P+P A S S + G
Sbjct: 371 SMTTPPMQAPPSLQT-IPPIQVPHSLT---SPSLQA------PPSPLALS-SLQATTSLG 419
Query: 1074 GGSSQGPALRYFQLPPRAASAAMYVPAR--SGRGRKGPLVKQTKVEGEPQKGGGLPPAPS 1131
+ Q + + PR A++ P+R S PL + P L PA S
Sbjct: 420 SPTLQA-THSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVS 478
Query: 1132 P-TSPASPQPPPAVAA-PSEKNSIPIPTII---------IKAPSTSSSGRSSQGSSTEAE 1180
P +SP + P A+++ S P+ ++I + PS + S E
Sbjct: 479 PLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENL 538
Query: 1181 PPTQPEPTGGGGGG------GSSPSPAPAMSPVPPSPSPVPTPASPSGPAT 1225
P P P + P PAP PPSP P P +PS AT
Sbjct: 539 PSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIAT 589
Score = 57.8 bits (138), Expect = 1e-07
Identities = 80/290 (27%), Positives = 101/290 (34%), Gaps = 51/290 (17%)
Query: 861 SFDPHHRAQPSYERPSF-LPPGPGLMLRQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSED 919
S P R P P +PP P L + P APPA L+ P +
Sbjct: 750 SATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKP----PPQAPPA------LATPPLQA 799
Query: 920 IPPPPTTSPPEPPYSTPPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSP---- 975
+P PP + P + P+S S TP P+ P +P S PAS +P
Sbjct: 800 LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPP 859
Query: 976 ---PDTRV-GSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHPPHPPEME---- 1027
PDT V G R GP PP P + P H + P E+
Sbjct: 860 TPGPDTSVSGPRLTLALAPGPPPPPSRSP---SSTLSGPDLAGHSSSATSTPEELRGYDS 916
Query: 1028 --TGGSPDDPPPRLAL----------GPQPSLRGWRG--GGPSPTPGAPSPSHHGSAGG- 1072
GG+ PPP L GP P L +RG G P P P A P GSA G
Sbjct: 917 GPEGGAAASPPPDAELAACHPAAWSRGPAPPL-AFRGAPGAPLPWPPATGP---GSADGL 972
Query: 1073 ------GGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKV 1116
G S PA P ++ A +G G KQ ++
Sbjct: 973 CTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARL 1022
Score = 52.0 bits (123), Expect = 6e-06
Identities = 127/496 (25%), Positives = 166/496 (33%), Gaps = 90/496 (18%)
Query: 1638 ASAAPG--DPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDH-PLETISSA 1694
A+ APG P PPG P P PPP T + + + + + PL +
Sbjct: 18 AARAPGLLTPRPPGSPRP-------------PPPVTPAALRVLGAAGAVGRKPLAERAGG 64
Query: 1695 STLSSL--SAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLM 1752
+++ SA G G + AS P G PP
Sbjct: 65 IGGATIPESAPRAGPTRSAGTSSRNPASRPPA-------------SGRGERAPPAKNTSP 111
Query: 1753 TPSKLRGRALGASGGLRPGPSG--GLRDPVTPTSPTVSVTGAGTDGLL---ALRACSGP- 1806
P GRA SG RPGP G GLR T T A L A R SGP
Sbjct: 112 GPVSSPGRA---SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT 168
Query: 1807 ---PTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPL-------PGPLA 1856
P+ +A A EV +P P S+ PR P EGP P P A
Sbjct: 169 PGTPSPAMARRSRAAGTEVG-LPRPAPSARPR---PPTEGPRKSVSSASEHSTTEPSPAA 224
Query: 1857 QPQASALATVKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHH----GGASYV 1912
+ + SA ++ LSS + +G P ARG G +
Sbjct: 225 RRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQPKPKGLQALR 281
Query: 1913 PERTSSLQRQRLS--DDSQSSLLSKPVSSLFQNWPKPP----LPPLPTGTGVSPTAAAAP 1966
P + + ++ SS L+ P S + P PP PLP SP A
Sbjct: 282 PPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPL 341
Query: 1967 GATSPSASSSSTSTRHLQGVEFEMRPPLLRRAPSPSLLPASEHKVS----PAPRPSSLPI 2022
PS S+ PP L+ PSP P S+ S P P SL
Sbjct: 342 PLAPPSPSA----------------PPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQT 385
Query: 2023 LPSGPLYPGLF--DIRGSPTGGAGGSADPFAPVFVPPHPGISGGLGGALSGASRSL-SPT 2079
+P + L ++ P+ A S + P L + SL SP+
Sbjct: 386 IPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPS 445
Query: 2080 RLLSLPPDKPFGAKPL 2095
R S PPD P PL
Sbjct: 446 RPASTPPDSPPLQAPL 461
Score = 51.2 bits (121), Expect = 1e-05
Identities = 87/351 (24%), Positives = 115/351 (32%), Gaps = 74/351 (21%)
Query: 937 PVPSSSGRLTPSPRGGPFNPGSGGP--LPASSPASFDGPSPPDTRVG-----SREKSLYH 989
P + G LTP P G P P P L A G P R G + +S
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
Query: 990 SGPL--------PPAHHHPPHHHHHHAPP--------------------PQPHHHHAHPP 1021
+GP PA P APP P P
Sbjct: 77 AGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI 136
Query: 1022 HPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPA 1081
E G + P R AL G R PTPG PSP+ G+ G
Sbjct: 137 SAEETVARGKATEAPKRSALS-----AGARRDTSGPTPGTPSPA-MARRSRAAGTEVG-- 188
Query: 1082 LRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVE------GEPQKGGGL--PPAPSPT 1133
LP A SA P R + + E P GGGL P + S +
Sbjct: 189 -----LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 243
Query: 1134 SPASPQPPPAVAAPSEKNSIPIPT----------IIIKAPSTSSSGRSSQGS--STEAEP 1181
S A+P PA + PS + + P ++ P + + + + + P
Sbjct: 244 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 303
Query: 1182 PTQPEPTGGGGGGGSSP----SPAPA-MSPVPPSPSPVP-TPASPSGPATL 1226
P P+G P +P PA + P PP +P+P P SPS P +L
Sbjct: 304 LATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSL 354
Score = 40.0 bits (92), Expect = 0.025
Identities = 48/155 (30%), Positives = 62/155 (40%), Gaps = 41/155 (26%)
Query: 421 RGPPGTGLTVPPALLRANSDTSMALPDW----MVFSAPGAASSGAPGPTSGSQGQSQPSA 476
RG PG L PPA ++D + + APGA PGP+ G
Sbjct: 951 RGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALD---PGPSPG--------- 998
Query: 477 PTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPR-----------E 525
+SG +A + GA +RSP + R E P G +S E
Sbjct: 999 -----TSGGKAAAGAGAGASSRSPKQARLGE----LPLGALQASVVQHLLSRTLLLAAAE 1049
Query: 526 GPAGGTGGSGGPGGSLG---SRGRRRKLYSAVPGR 557
G AGG+G GGPGG+ G + G R L A GR
Sbjct: 1050 GAAGGSG--GGPGGAEGGGVTGGARAALSDAELGR 1082
Score = 33.5 bits (75), Expect = 2.3
Identities = 25/80 (31%), Positives = 33/80 (41%), Gaps = 6/80 (7%)
Query: 460 GAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRP-S 518
G P P ++ + P +SS + S + P A R PS G ++P R S
Sbjct: 188 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG----GGLQRPASRSLS 243
Query: 519 SSGTPREGPA-GGTGGSGGP 537
SS TP PA G G P
Sbjct: 244 SSATPLSSPARSGPSARGTP 263
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 142 bits (359), Expect = 3e-33
Identities = 270/1063 (25%), Positives = 359/1063 (33%), Gaps = 202/1063 (19%)
Query: 834 SASESPGPGGLASLGKHRPKGFFATESSFDPHHR------------AQPSYERPSFLPPG 881
+A +PGP L G F + S+ + + S + P F PP
Sbjct: 120 TAMHTPGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPA 179
Query: 882 PGLMLRQKSIGAAEDDRPYLAPPAMKFSRSLS--VPGSEDI----PPPPTTSPPEPPYST 935
GL+ + P + P ++ F R V G + PP PP+PP
Sbjct: 180 NGLLSPHDVLHLKPSQAPTV-PSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPP 238
Query: 936 PPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPP 995
+P+ L S S L S A+ GP PP+ + ++ + H P
Sbjct: 239 RHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAA-PGPPPPERALPRQDTVIKHYQR--P 295
Query: 996 AHHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGP 1055
A PP PPP P H H + GGS R L P GG
Sbjct: 296 ASAQPP-------PPPPPAHALQH-----YLSCGGSYPSMGHRANLACSPL------GGG 337
Query: 1056 SPTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTK 1115
P+PGA PS G +G G+S G A P AA A G G P+++
Sbjct: 338 EPSPGAGEPSKAGPSGATAGAS-GRA-----TGPEAAGGG---GAGGGGGGYRPIIQSPG 388
Query: 1116 VEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGS 1175
+ KGG A T P PPP A + S+ P S +G G+
Sbjct: 389 Y--KTGKGGYGAAAGGATRP----PPPRSTATPKCQSLGGPAAAYATGKASGAG----GA 438
Query: 1176 STEAEPPTQPE--------PTGGGGGGGSSPSPAPAMSPVPPSP---------------- 1211
+A P QP+ G GGG S AP+ S PP P
Sbjct: 439 GGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYS 498
Query: 1212 -------------SPVPTPAS-----PSGPATLDFTSQFGAALVGAARREGGWQNEA--- 1250
P P PA+ P+ +L +++ AL G GGW +
Sbjct: 499 PDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSG---HGGGWGPSSLGG 555
Query: 1251 ---RRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSG 1307
S + + G G+G+ APG L S + F A P +AG+G
Sbjct: 556 GGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYL--SSVLASAPFLAPPGAGSYAAGAG 613
Query: 1308 AGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKES 1367
GY G G GS G GG A + + H L +A P G E ++
Sbjct: 614 -GYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLL--QAPSPPRTSGADGLVGEDGAADA 670
Query: 1368 SEGGGAPQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLG 1427
S+G G PP YE P + H + V+R AS + A L G
Sbjct: 671 SKGLGGSGGAGGPPGTPYELAKEDPQRY----HLQSVIRT-SASLDEGATAALELGLGRL 725
Query: 1428 SQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPER 1487
++K P L + G L L PP P P +A +P
Sbjct: 726 KEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPP-------TAQSTQP-- 776
Query: 1488 LPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSVP------PSPTSPRASEENG 1541
P + GP D P V PP P + +P PSP SP AS+ G
Sbjct: 777 -----------TPHGLLLEAGGP---DLPLVLPPPPPQLLPSVLSHAPSP-SPSASKV-G 820
Query: 1542 LPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLP-DTPAPAT 1600
+ LL PA DG P PPP P P PP PL + +
Sbjct: 821 VHLL---EPA----TRDG-----APQPPP-----------PPPPPPPPMPLQLEAHLRSH 857
Query: 1601 PLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAA 1660
L P P +LD + E+ + APGD GPP PA
Sbjct: 858 GLEPAAPSPRLRPEESLDPPGAM-----QELLGALEPLPPAPGDT-GVGPPNSEGKDPAG 911
Query: 1661 PQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAG----------- 1709
P P + S D L+ + + GGG+A
Sbjct: 912 AYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDE 971
Query: 1710 GGGGAGAGVASGPELLDTYVAYLDGQAFG-GSSTPG----PPYPPQLMTPSKLRGRALGA 1764
G AGAG GP D Y Y G+A G G TPG P PP+L PS + LG
Sbjct: 972 GDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPEL--PSTVNAEPLGL 1029
Query: 1765 SGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPP 1807
++ GP P P P + GL + CS P
Sbjct: 1030 ---IQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKP 1069
Score = 85.9 bits (211), Expect = 4e-16
Identities = 194/832 (23%), Positives = 255/832 (30%), Gaps = 190/832 (22%)
Query: 875 PSFLPPGPGLMLRQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYS 934
P LPP P +L A P +P A K L P + D P P PP PP
Sbjct: 791 PLVLPPPPPQLLPSVLSHA-----PSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPP-- 843
Query: 935 TPPVP-------SSSGR--LTPSPRGGP---FNP--------GSGGPLPASSPASFDGPS 974
PP+P S G PSPR P +P G+ PLP P+
Sbjct: 844 -PPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLP---------PA 893
Query: 975 PPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHP------------PH 1022
P DT VG G P + P AP P P P
Sbjct: 894 PGDTGVGPPNSE----GKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPT 949
Query: 1023 PPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPAL 1082
EM GG+ DD GP P G G P PG P+ +G G S GP
Sbjct: 950 MEEMFGGGAADDYGKA---GP-PEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPET 1005
Query: 1083 RYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPP- 1141
L P P PL ++ P + PP P P PA P
Sbjct: 1006 PGLGLDPNKP------PELPSTVNAEPL---GLIQSGPHQAAPPPPPPPPPPPAPASEPK 1056
Query: 1142 -----------------------------PAVAAP-----------SEKNSIPIPTIII- 1160
P P ++++ +P I
Sbjct: 1057 GGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRL 1116
Query: 1161 ---KAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPS----- 1212
+ P SS RS S + P G G P A PP P
Sbjct: 1117 NPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRI 1176
Query: 1213 ---PVPTPASPSGPATLDFTSQF----GAALVGAARREGGWQNEARRRSTLFLSTDAGDE 1265
VPT A P+ +T ++ G A GG + E + + LS E
Sbjct: 1177 RPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGE 1236
Query: 1266 DGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGAGSRAYGGGGG 1325
GLGT + S+D + + +++ + G
Sbjct: 1237 -----GLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEE----------KQPEMKSGF 1281
Query: 1326 SSAFTSFLPPRPLVHPLTGKALDP--ASPLGLALAARERALKESSEGGGAPQPPPRPPSP 1383
++F FL PL L P + P + + R L+ PQPP P P
Sbjct: 1282 MASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQ--------PQPPATPAVP 1333
Query: 1384 RYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARR-------ELGYRAGLGSQEKSLPAS 1436
PPP+ A G P P +R L S E+ A
Sbjct: 1334 H---PPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAK 1390
Query: 1437 PPAARRSLLHRL-----PPTA-------PGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEE 1484
+ S+ + PP A P PL P P PG+ + PE
Sbjct: 1391 NRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEP 1450
Query: 1485 PERLPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPL 1544
P LE P P + P + P PPP P+ ++P P + + P
Sbjct: 1451 P--------LLEEKPPPTPPPA---PTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPP 1499
Query: 1545 LVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHP-LPDT 1595
+ PPP P++ P PPP + PE P P P P LPDT
Sbjct: 1500 PLPPPPPPAMP--------SPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDT 1543
Score = 82.0 bits (201), Expect = 6e-15
Identities = 293/1219 (24%), Positives = 384/1219 (31%), Gaps = 319/1219 (26%)
Query: 827 AAAQQTISASESPGPGGLASLGKHRPKGFFATESSFDPHHRAQ-------PSYE----RP 875
AAA T AS + G GG A +P+G ++ Q PSY +P
Sbjct: 424 AAAYATGKASGAGGAGGQA-YSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQP 482
Query: 876 SFLPPGPGL---------MLRQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTT 926
PP PGL L+ + G + PY P A S+ +P T
Sbjct: 483 PSGPPPPGLATCQSYSPDQLQGQLYGVQGE--PYPGPAAH----------SQGLP----T 526
Query: 927 SPPEPPYSTPPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGP--SPPDTR----V 980
+ P YST P+ SG GG + P S G +SP+ P SPP T V
Sbjct: 527 ASPSLSYSTGHSPALSGH------GGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGV 580
Query: 981 GSR-EKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHH-------AHPPHPPEMETGGSP 1032
GS Y S L A P +A + A P PP T
Sbjct: 581 GSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDE- 639
Query: 1033 DDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGP-------ALRYF 1085
+ L P P G A + G +GG GG P RY
Sbjct: 640 EFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYH 699
Query: 1086 QLPPRAASAAMYVPARS----GRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPP 1141
SA++ A + G GR + K +G P++GG P + +
Sbjct: 700 LQSVIRTSASLDEGATAALELGLGRL-----KEKKKG-PERGGETPEGLATSVVHYGAGA 753
Query: 1142 PAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPA 1201
+ A +K+ P P P+ S+ + G EA P P P P
Sbjct: 754 KELGAFLQKSPPPPP------PTAQSTQPTPHGLLLEAGGPDLPLVL---------PPPP 798
Query: 1202 PAMSPVPPSPSPVPTPASPSGPATLDFTSQFGAALVGAARREGGWQNEARRRST---LFL 1258
P + P S +P P+P++ S+ G L+ A R+G Q + L
Sbjct: 799 PQLLPSVLSHAPSPSPSA----------SKVGVHLLEPATRDGAPQPPPPPPPPPPPMPL 848
Query: 1259 STDAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGAGSR 1318
+A G AAP PRLR +S+D E LE G G G +
Sbjct: 849 QLEAHLRSHGL----EPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNS 904
Query: 1319 AYGGGGGSSAFTSFLPP---RPLVHPLTGKALDPASPLGLALAARERALKESSE---GGG 1372
G + A+ S P P PLT + L ER+ + E GGG
Sbjct: 905 E--GKDPAGAYRSPSPQGTKAPRFVPLTSICFPDS-----LLQDEERSFFPTMEEMFGGG 957
Query: 1373 APQ------PPPRPPSPRYEA-PPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAG 1425
A PP P+ A PPP P + P+ + P R GA P P G
Sbjct: 958 AADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPG-RASGAGPETP---------G 1007
Query: 1426 LGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEP 1485
LG P PP LP T L+Q G AP P P A EP
Sbjct: 1008 LGLD----PNKPP--------ELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEP 1055
Query: 1486 ERLPLHVRFLENCQPRAPVTSG------RGPP----------------SEDGPGVPPP-- 1521
+ F + TS R PP ED VP
Sbjct: 1056 KGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIR 1115
Query: 1522 -SPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKP 1580
+PRR +P +S R+ P +P D++ F P P P KP
Sbjct: 1116 LNPRR-LPDLVSSCRSR----------PALSPLGDID-----FCPPNPGPDGPRRRGRKP 1159
Query: 1581 ESPLTPGPPHP----------LPDTPAPA----------------------------TPL 1602
GPP P +P T PA T L
Sbjct: 1160 TKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRL 1219
Query: 1603 PPVPPPAVAAAPP-------TLDSTASSLTSYDSEVATLTQGASAAP------------- 1642
P+ P + + P T A S T ++S ++LT+ A
Sbjct: 1220 EPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKS 1279
Query: 1643 ------------GDPHPP----------GPPA---PAAPA----------PAAPQPGPDP 1667
G HPP PP P+ PA PA P P P
Sbjct: 1280 GFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSG 1339
Query: 1668 PPGTDSGIEEVDSRS---SSDHPLETIS-----SASTLSSLSAEGGGSAGGGGGAGAGVA 1719
G +E +S P + + + TL S S++ S ++
Sbjct: 1340 AFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESIS 1399
Query: 1720 SGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGPSGGLRDP 1779
S LD D G T P PP A PGP P
Sbjct: 1400 SAISALD------DPPLAGPKDTSTPDGPPL-------------APAAAVPGP------P 1434
Query: 1780 VTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLP 1839
P P+ + G LL + PPT A P P PP P P S P + P
Sbjct: 1435 PLPGLPSANSNGTPEPPLLEEKP---PPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAP 1491
Query: 1840 WEEGPGPPPPPLPGPLAQP 1858
P PPP P P P A P
Sbjct: 1492 TPSSPPPPPLPPPPPPAMP 1510
Score = 77.8 bits (190), Expect = 1e-13
Identities = 129/523 (24%), Positives = 170/523 (32%), Gaps = 98/523 (18%)
Query: 1435 ASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPH-------PGVSKPWRSAAPEEPER 1487
A P A+ +L+ L P GP L ++ +P PG ++ + S A
Sbjct: 82 AGPDASVMNLISALESRGPQPGPSASSLLSQFRSPSWQTAMHTPGPTELFISGA------ 135
Query: 1488 LPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVL 1547
LP F P + S P+ G P S+ P SP A NGL
Sbjct: 136 LPGSSTF-----PSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPA---NGL----- 182
Query: 1548 PPPAPSVDVEDGEFLFVEPLPPP-LEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVP 1606
+ + L ++P P + S FE+ GP P P P PP P
Sbjct: 183 --------LSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDP 234
Query: 1607 PPAVAAAPP---TLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAP------- 1656
PP P L S++++ + + L + AAPG P PP A P
Sbjct: 235 PPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPP----PPERALPRQDTVIK 290
Query: 1657 ---APAAPQPGPDPPP----------------------------GTDSGIEEVDSRSSSD 1685
PA+ QP P PPP G S +
Sbjct: 291 HYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAG 350
Query: 1686 HPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGP 1745
T ++ + A GGG AGGGGG + P Y G A GG++ P P
Sbjct: 351 PSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGY--GAAAGGATRPPP 408
Query: 1746 PYPPQLMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPT----VSVTGAGTDGLLALR 1801
P L G A + G G G +P P G G G A
Sbjct: 409 PRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQD 468
Query: 1802 ACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLAQPQAS 1861
P +GGP PP L T S L + G P PGP A Q
Sbjct: 469 LSKAP---SYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQL-YGVQGEPYPGPAAHSQGL 524
Query: 1862 ALATVKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDS 1904
A+ S + S L GG W GGGG++
Sbjct: 525 PTASPSLSYSTGHSPALSGHGGG--------WGPSSLGGGGEA 559
Score = 68.9 bits (167), Expect = 5e-11
Identities = 90/316 (28%), Positives = 110/316 (34%), Gaps = 96/316 (30%)
Query: 1457 PLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPRAPVTSG--RGPPS-- 1512
P L Q G PP P +S P P R QP+ P T PPS
Sbjct: 1296 PPLYQAGLTPPLSPP------KSVPPSVPAR---------GLQPQPPATPAVPHPPPSGA 1340
Query: 1513 -----------EDGPGVPPPSP--------RRSVPPSPTSPRASEEN------------- 1540
+G G+ PSP +R++ P+ E++
Sbjct: 1341 FGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISS 1400
Query: 1541 GLPLLVLPPPAPSVDVE--DGEFLF---VEPLPPPLE---FSNSFEKPESPLTPGPPHPL 1592
+ L PP A D DG L P PPPL +NS PE PL P P
Sbjct: 1401 AISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPT 1460
Query: 1593 PD---TPAPATPLPPVPP-PAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPP 1648
P TP P P PP PP PA+ + PP + T SS PP
Sbjct: 1461 PPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSS-----------------------PP 1497
Query: 1649 GPPAPAAPAPAAPQPGPDPPPGT---DSGIEEVDSRSSSD------HPLETISSASTLSS 1699
PP P P PA P P P PPP + EE + S D PL T ++
Sbjct: 1498 PPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQET-AA 1556
Query: 1700 LSAEGGGSAGGGGGAG 1715
+ E AG GG G
Sbjct: 1557 VCGETDEEAGESGGEG 1572
Score = 64.7 bits (156), Expect = 9e-10
Identities = 157/662 (23%), Positives = 200/662 (30%), Gaps = 165/662 (24%)
Query: 926 TSPPEPPYSTPPVPSSSGRLTPSPRGGPFNP--------GSGGPLPASSPASFD-GPSPP 976
T P PP S PP + G L P P P P G GG L A+ G P
Sbjct: 1304 TPPLSPPKSVPPSVPARG-LQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSP 1362
Query: 977 DTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHA--HPPHPPEMETGGSPDD 1034
R+ K + P + + A PP +T +PD
Sbjct: 1363 CKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTS-TPDG 1421
Query: 1035 PPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASA 1094
PP L P ++ G P P PG PS + +G+
Sbjct: 1422 PP----LAPAAAVPG-----PPPLPGLPSANSNGTP------------------------ 1448
Query: 1095 AMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSIP 1154
+ PL+++ PP P P PQPPP P P
Sbjct: 1449 ------------EPPLLEEKP-----------PPTPPPAPTPQPQPPPPPPPPQPALPSP 1485
Query: 1155 IPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPSPV 1214
P + AP+ SS PP P P P PA A PP
Sbjct: 1486 PPLV---APTPSS----------PPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAA 1532
Query: 1215 PTPASPSGPATLDF---TSQFGAALVGAARR---EGGWQNEARRRSTLFLSTDAGDEDGG 1268
P+P P P T Q AA+ G E G + R R + A D
Sbjct: 1533 PSPEDPELPDTRPLHLAKKQETAAVCGETDEEAGESGGEGIFRERDEFVIR--AEDIPSL 1590
Query: 1269 DGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGY-GAGSRAYGGGGGSS 1327
L TG P P R K++ + F+ E + + Y GY G Y
Sbjct: 1591 KLALQTGREPPPIWRVQKALLQ-KFTPEIKDGQRQFCATSNYLGYFGDAKNRY-----QR 1644
Query: 1328 AFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKESSEGGGAPQPPPRP-PSPRYE 1386
+ FL + A P + + +A S GG + PP P P P+ E
Sbjct: 1645 LYVKFLENVNKKDYVRVCARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPE 1704
Query: 1387 APPPTPHHHSPHAHHEPVLRLWGASPPDPARREL---------------------GYRAG 1425
P T P E + PP P + L G RA
Sbjct: 1705 TPEKTTSEKPPEQTPETAM----PEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERAT 1760
Query: 1426 LGSQ---EKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAP 1482
G Q E+SL PA RLP P ++ EPP P K W A
Sbjct: 1761 SGRQTRPERSLATGQPAT-----SRLPKARP------TKVKAEPP---PKKRKKWLKEA- 1805
Query: 1483 EEPERLPLHVRFLENCQPRAPVTSGRGPP-----SEDGPGVPPPSPRRSVPPSPTSPRAS 1537
T+G GPP SE PG P R+VP RA
Sbjct: 1806 ------------------GGNATAGGGPPGSSSDSESSPGA-PSEDERAVPGRLLKTRAM 1846
Query: 1538 EE 1539
E
Sbjct: 1847 RE 1848
Score = 61.2 bits (147), Expect = 1e-08
Identities = 221/958 (23%), Positives = 294/958 (30%), Gaps = 238/958 (24%)
Query: 1304 AGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLV--HPLTGKALD--PASPLGLALAA 1359
AG+G Y S YG S T L + HPL A + PA GL
Sbjct: 16 AGAGWSYERSAKASLVYGSSRTSHPETDILHRQAYAAPHPLQSYATNHHPAGLSGLFDTG 75
Query: 1360 RERA-----------LKESSEGGGAPQPPPRPPS--PRYEAPPPTPHHHSPHAHHEPVLR 1406
A L + E G PQP P S ++ +P H+P +
Sbjct: 76 LHHAGSAGPDASVMNLISALESRG-PQPGPSASSLLSQFRSPSWQTAMHTPGPTELFISG 134
Query: 1407 LWGASPPDPARRELG---YRAGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLG 1463
S P+ L + A GS+ +P+S L + PP +P LL
Sbjct: 135 ALPGSSTFPSSSALSAYQHPASFGSRPFPVPSS-------LSLQDPPFSPPANGLL---- 183
Query: 1464 TEPPAPHPGVS-KPWRSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPPPS 1522
+PH + KP S AP P L A + + PP GP PPP
Sbjct: 184 ----SPHDVLHLKP--SQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPP 237
Query: 1523 PRR-----SVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSF 1577
PR ++ S ++ A+ E P L F P PPP
Sbjct: 238 PRHLPTQFNLLASSSAAAAAAEQSSPQLY-------------NFSGAAPGPPP------- 277
Query: 1578 EKPESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTAS--SLTSYDSEVATLT 1635
PE L P + PA+ PP PPP A L S S+ + +
Sbjct: 278 --PERAL-PRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPL 334
Query: 1636 QGASAAPG--DPHPPGPPAPAAPA-----------------------PAAPQPGPDPPPG 1670
G +PG +P GP A A P PG G
Sbjct: 335 GGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKG 394
Query: 1671 TDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVA 1730
+R T S +A G A G GGAG S +
Sbjct: 395 GYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGP 454
Query: 1731 YLDGQAFGG----------SSTPGPPYPP-----------QLMTPSKLRGRALGASGGLR 1769
GQ FGG S + GPP PP Q +P +L+G+ G G
Sbjct: 455 QAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPY 514
Query: 1770 PGPSGGLRDPVTPT---------SPTVSVTGAGTDG-----------------LLALRAC 1803
PGP+ + T + SP +S G G L + A
Sbjct: 515 PGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPAT 574
Query: 1804 SGPPTAGVAGGP----VAVEPEVPPVPLPTASSLPRKLLPWE---------EGPGPPPPP 1850
PP G G P +V P + P A S ++ GPG PP
Sbjct: 575 GRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAE 634
Query: 1851 LPGP---LAQPQASALATVKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHG 1907
L Q A + + S L + S GG+ GG+GG + +
Sbjct: 635 RTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGS-----GGAGGPPGTPYE 689
Query: 1908 GASYVPER---TSSLQRQRLSDDSQSSLLSKPVSSLFQNWPKP----------------- 1947
A P+R S ++ D+ ++ L + L + P
Sbjct: 690 LAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHY 749
Query: 1948 --------------PLPPLPTGTGVSPT----AAAAPGATSPSASSSSTSTRHLQGVEFE 1989
P PP PT PT A G P L +
Sbjct: 750 GAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLV---------LPPPPPQ 800
Query: 1990 MRPPLLRRAPSPS---------LLPASEHKVSPAPRPSSLPILPSGPLY-------PGLF 2033
+ P +L APSPS LL + +P P P P P PL GL
Sbjct: 801 LLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLE 860
Query: 2034 DIRGSPTGGAGGSADPFAPVF--------VPPHPGISG-----GLGGALSGASRSLSP 2078
SP S DP + +PP PG +G G +GA RS SP
Sbjct: 861 PAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSP 918
Score = 58.5 bits (140), Expect = 7e-08
Identities = 272/1213 (22%), Positives = 363/1213 (29%), Gaps = 266/1213 (21%)
Query: 957 GSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQP--- 1013
G G PL A + S++ + GS S + L + PH +A P
Sbjct: 9 GFGDPLGAGAGWSYERSAKASLVYGSSRTSHPETDILHRQAYAAPHPLQSYATNHHPAGL 68
Query: 1014 --------HHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPS 1065
HH + P M + + P+ L +R P P+
Sbjct: 69 SGLFDTGLHHAGSAGPDASVMNLISALESRGPQPGPSASSLLSQFRSPSWQTAMHTPGPT 128
Query: 1066 HHGSAGGGGGSSQGP---ALRYFQLPPRAASAAMYVPARSG------------------- 1103
+G GSS P AL +Q P S VP+
Sbjct: 129 ELFISGALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDV 188
Query: 1104 ---RGRKGPLVKQTKVEGEPQKGGGLPPA---PSPTSPASPQPPPAVAAPSEKNSIPIPT 1157
+ + P V + GG L PA P+ T P P PP P +PT
Sbjct: 189 LHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRH-----LPT 243
Query: 1158 IIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPSPV--- 1214
S+S++ +++ SS + G++P P P +P + +
Sbjct: 244 QFNLLASSSAAAAAAEQSSPQLY-----------NFSGAAPGPPPPERALPRQDTVIKHY 292
Query: 1215 --PTPASPSGPATLDFTSQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDEDGGDGGL 1272
P A P P Q + G+ G R+ L S G E G
Sbjct: 293 QRPASAQPPPPPPPAHALQHYLSCGGSYPSMG-------HRANLACSPLGGGEPSPGAGE 345
Query: 1273 GTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGAGSRAYGGGGGSSAFTSF 1332
+ A P +G+ AG G G A GGGG +
Sbjct: 346 PSKAGP-------------------------SGATAGASGRATGPEAAGGGGAGGGGGGY 380
Query: 1333 LPPRPLVHPLTGKALDPASPLGLALAARERALKESSEGGGAPQPPPRPPSPRYEAPPPTP 1392
P TGK G AA GGA +PPP PR A P
Sbjct: 381 RPIIQSPGYKTGKG-------GYGAAA-----------GGATRPPP----PRSTATPKCQ 418
Query: 1393 HHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAARRSLLHRLPPTA 1452
P A + A + G G Q S P P L P A
Sbjct: 419 SLGGPAAAY--------------ATGKASGAGGAGGQAYS-PGQPQGL-------LGPQA 456
Query: 1453 PGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPRAP--------- 1503
G G Q AP P + P P L CQ +P
Sbjct: 457 YGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPG--------LATCQSYSPDQLQGQLYG 508
Query: 1504 VTSGRGP-PSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFL 1562
V P P+ G+P SP S SP S G P + E
Sbjct: 509 VQGEPYPGPAAHSQGLPTASPSLSYSTGH-SPALSGHGG----GWGPSSLGGGGEASPSH 563
Query: 1563 FVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTAS 1622
+ PL +SP G P + AP L V A APP S A+
Sbjct: 564 IIRPL-------------QSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAA 610
Query: 1623 SLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRS 1682
Y + G+ G P GPPA D
Sbjct: 611 GAGGYKGK----GDGSELLAG---PGGPPAERTE----------------------DEEF 641
Query: 1683 SSDHPLETISSASTLSS--LSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGS 1740
H L+ S T + L E G + G G+G A GP +A D Q +
Sbjct: 642 LIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQ 701
Query: 1741 STPGPPYPPQLMTPSKLRGRALGAS----GGLRPGPSGGLRDPVTPTSPTVSVT--GAGT 1794
S + T + L A A G L+ G R TP SV GAG
Sbjct: 702 SV--------IRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGA 753
Query: 1795 DGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPG-----PPPP 1849
L A S PP PP + P LL GP PPPP
Sbjct: 754 KELGAFLQKSPPP---------------PPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPP 798
Query: 1850 P--LPGPLAQPQASALATVKASI-ISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHH 1906
P LP L+ + + + K + + E +++ G+ P ++H
Sbjct: 799 PQLLPSVLSHAPSPSPSASKVGVHLLEPATR----DGAPQPPPPPPPPPPPMPLQLEAHL 854
Query: 1907 GGASYVPERTSSLQRQRLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGVSPTAAAAP 1966
P S R S D ++ + + +L PLPP P TGV P +
Sbjct: 855 RSHGLEPAAPSPRLRPEESLDPPGAM-QELLGAL------EPLPPAPGDTGVGPPNSE-- 905
Query: 1967 GATSPSASSSSTSTRHLQGVEFEMRPPLLRRAPSPSLLPASEHKVSPAPRPSSLPILPSG 2026
P+ + S S QG + PL SLL E P
Sbjct: 906 -GKDPAGAYRSPSP---QGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADD 961
Query: 2027 PLYPGLFDIRGSPTGGAGGSADPFA-PVFVPPHPGISGGLGGALSGASRSLSPTRLLSLP 2085
G + G P GAG P A + P PG + G G G L P + P
Sbjct: 962 YGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGL--GLDPNK----P 1015
Query: 2086 PDKP--FGAKPLG 2096
P+ P A+PLG
Sbjct: 1016 PELPSTVNAEPLG 1028
Score = 51.6 bits (122), Expect = 8e-06
Identities = 111/487 (22%), Positives = 146/487 (29%), Gaps = 116/487 (23%)
Query: 1374 PQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLR----------LWGASPPDPARRELGYR 1423
P P P P R P P P +R ++P D A++ G
Sbjct: 1145 PNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRG 1204
Query: 1424 AGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPE 1483
G G + + + + L +L G G LGT G ++
Sbjct: 1205 RGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEG-----LGTSSGDAISGTDHNSLDSSLT 1259
Query: 1484 EPERLPLHVRFLENCQPRAP----------VTSG-RGPPSEDGPGVPPPSPRRSVPPSPT 1532
E++ ++ +E QP + SG R PP PP SP +SVPPS
Sbjct: 1260 R-EKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVP 1318
Query: 1533 SPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPP---LEFSNSFEKPESP-LTPGP 1588
+ + PP P+V P PPP + E ES L G
Sbjct: 1319 ARGLQPQ--------PPATPAV-----------PHPPPSGAFGLGGALEAAESEGLGLGC 1359
Query: 1589 PHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPP 1648
P P P + ++ S S ++ L A P D P
Sbjct: 1360 PSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTP 1419
Query: 1649 -GPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGS 1707
GPP APAA PGP P PG S +S + + PL T
Sbjct: 1420 DGPPL----APAAAVPGPPPLPGLPSA----NSNGTPEPPLLEEKPPPTPPP-------- 1463
Query: 1708 AGGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGG 1767
A P+ P PP PPQ PS
Sbjct: 1464 -----------APTPQ----------------PQPPPPPPPPQPALPSP--------PPL 1488
Query: 1768 LRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPL 1827
+ P PS P+ P P S PP A P+A PE P P
Sbjct: 1489 VAPTPSSPPPPPLPPPPPPAMP--------------SPPPPPPPAAAPLAAPPEEPAAPS 1534
Query: 1828 PTASSLP 1834
P LP
Sbjct: 1535 PEDPELP 1541
Score = 49.7 bits (117), Expect = 3e-05
Identities = 238/1103 (21%), Positives = 317/1103 (28%), Gaps = 282/1103 (25%)
Query: 762 MDEAVHKKAPQQAKRLPPPTISLRSKSMTSELEEMEYEQQPA-PVPSMEKKRTVYQMALN 820
++ A APQ PPP + + E + +PA P P + + ++
Sbjct: 824 LEPATRDGAPQPPPPPPPPPPPM---PLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGA- 879
Query: 821 KLDEILAAAQQTISASESPGPGGLASLGKHRPKGFFATESSFDPHHRAQPSY-------- 872
+ E+L A + A G G S GK P G + + S P P +
Sbjct: 880 -MQELLGALEPLPPAPGDTGVGPPNSEGKD-PAGAYRSPS---PQGTKAPRFVPLTSICF 934
Query: 873 -------ERPSFLPPGPGLMLRQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPT 925
E SF P + + G A DD PP E P
Sbjct: 935 PDSLLQDEERSFFPT-----MEEMFGGGAADDYGKAGPPE-----------DEGDPKAGA 978
Query: 926 TSPPEPPYSTPPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREK 985
PP PP P P GR + + GP PG G L + P P P T V +
Sbjct: 979 GPPPGPPAYDPYGPYCPGRASGA---GPETPGLG--LDPNKP-----PELPST-VNAEPL 1027
Query: 986 SLYHSGPLPPAHHHPPHHHHHHAPPPQPH---------------------HHHAHPPHPP 1024
L SGP A PP AP +P H PP
Sbjct: 1028 GLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPP 1087
Query: 1025 ------------EMETGGSPDDPPPRLALGPQ--PSLRGWRGGGPS-----------PTP 1059
E E D P + L P+ P L P+ P P
Sbjct: 1088 FQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNP 1147
Query: 1060 GAPSPSHHG-----SAGGGGGSSQG-PALRYFQLPPRAASAAMYVPARS---------GR 1104
G P G + G +G P +R ++P A A+ P GR
Sbjct: 1148 GPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGR 1207
Query: 1105 GRKGPLVKQTKVE---------GEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPI 1155
GRK T++E P+ G GL + + + EK I
Sbjct: 1208 GRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKI 1267
Query: 1156 PTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPS------PAPAMSPVPP 1209
+ K P S +S ++ P G S P PA + P PP
Sbjct: 1268 KEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPP 1327
Query: 1210 S----PSPVPTPASPSGPATLDFTSQ-FGAALVGAARREGGWQNEARRRSTLFLSTDAGD 1264
+ P P P+ A G A S+ G +R +E +R+ L + + D
Sbjct: 1328 ATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKR----LDEELKRNLETLPSFSSD 1383
Query: 1265 EDGG-----------------------DGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRL 1301
E+ G T GP L + ++ P L
Sbjct: 1384 EEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVP----GPPPLPGL 1439
Query: 1302 ESAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARE 1361
SA S G PP P P P P
Sbjct: 1440 PSANSN--------------GTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSP 1485
Query: 1362 RALKESSEGGGAPQPPPRPPSPRYEAPPPT-PHHHSPHAH--HEPVLRLWGASPPDPA-- 1416
L + P P P PP P +PPP P +P A EP SP DP
Sbjct: 1486 PPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPA----APSPEDPELP 1541
Query: 1417 ---------RRELGYRAGLGSQEKSLPASPPAAR-RSLLHRLPPTAPGVGPLLLQLGTEP 1466
++E G +E R R P + L LQ G EP
Sbjct: 1542 DTRPLHLAKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSL-KLALQTGREP 1600
Query: 1467 PAPHPGVSKPWRSAAPE---------------------EPERLPLHVRFLENC------- 1498
P + PE + L+V+FLEN
Sbjct: 1601 PPIWRVQKALLQKFTPEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVR 1660
Query: 1499 --------QPRAPVT---SGRGPPSEDGPGVPPPS-----PRRSVPPSPTSPRASEENGL 1542
+P PV + P S G PPP P+ P TS + E+
Sbjct: 1661 VCARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQT-- 1718
Query: 1543 PLLVLP-PPAPSVD--------------VEDGEFLFVEPLPPPLEFSNSFEKPESPLTPG 1587
P +P PPAP V GE PL S +PE L G
Sbjct: 1719 PETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGE----RPLRGERATSGRQTRPERSLATG 1774
Query: 1588 PPHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHP 1647
P + LP P V A PP L + A P
Sbjct: 1775 QP--------ATSRLPKARPTKVKAEPPP-----------KKRKKWLKEAGGNATAGGGP 1815
Query: 1648 PGPPAPAAPAPAAPQPGPDPPPG 1670
PG + + +P AP PG
Sbjct: 1816 PGSSSDSESSPGAPSEDERAVPG 1838
Score = 45.4 bits (106), Expect = 6e-04
Identities = 113/450 (25%), Positives = 152/450 (33%), Gaps = 104/450 (23%)
Query: 1683 SSDHPLETISS---ASTLSSLSAEGGGSAGGGGGAGA-----------GVASGPELLDTY 1728
++ HPL++ ++ + LS L G AG G + G GP
Sbjct: 51 AAPHPLQSYATNHHPAGLSGLFDTGLHHAGSAGPDASVMNLISALESRGPQPGPSASSLL 110
Query: 1729 VAYLDGQAFGGSSTPGP---------PYPPQLMTPSKLRGRALGASGGLRPGP---SGGL 1776
+ TPGP P + S L AS G RP P S L
Sbjct: 111 SQFRSPSWQTAMHTPGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSL 170
Query: 1777 RDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAG------VAGGPVAVEPEVPPVPLPTA 1830
+DP P SP + + D +L L+ P +AGG V + P L A
Sbjct: 171 QDP--PFSPPANGLLSPHD-VLHLKPSQAPTVPSSLGFERLAGGGV-----LGPAGLGPA 222
Query: 1831 SSLPRKLLPWEEGPGPPPPPLPGPLAQPQASALATVKASIISELSSKLQQFGGSSAAGGA 1890
+ P + PGPP PP P Q + LA+ A+ + S Q + S AA G
Sbjct: 223 QTPPYR-------PGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGP 275
Query: 1891 LPWARGGSGGGGDSHHGGASYVPERTSSLQRQRLSDDSQSSLLSKPVSSLFQNWPKPPLP 1950
P PER +L RQ D+ +P S+ +PP P
Sbjct: 276 PP--------------------PER--ALPRQ----DTVIKHYQRPASA------QPPPP 303
Query: 1951 PLPTGTGVSPTAAAAPGATSPSASSSSTSTRHLQGVEFEMRPPLLRRAPSPSLLPASEHK 2010
P P A A S S S R PL PSP S K
Sbjct: 304 P--------PPAHALQHYLSCGGSYPSMGHRANLACS-----PLGGGEPSPGAGEPS--K 348
Query: 2011 VSPAPRPSSLPILPSGPLYPGLFDIRGSPTGGAGGSADPFAPVFVPP-HPGISGGLGGAL 2069
P+ + +GP G GGAGG + P+ P + GG G A
Sbjct: 349 AGPSGATAGASGRATGPEAAG--------GGGAGGGGGGYRPIIQSPGYKTGKGGYGAAA 400
Query: 2070 SGASRSLSPTRLLSLPPDKPFGAKPLGFWT 2099
GA+R P R + P + G + T
Sbjct: 401 GGATRP-PPPRSTATPKCQSLGGPAAAYAT 429
Score = 32.7 bits (73), Expect = 4.0
Identities = 35/133 (26%), Positives = 48/133 (36%), Gaps = 18/133 (13%)
Query: 411 QESPK---YAARRRGPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSG 467
Q SP+ ++ GPP PP DT + + P +A P P +
Sbjct: 260 QSSPQLYNFSGAAPGPP------PPERALPRQDTVIKH-----YQRPASAQPPPPPPPAH 308
Query: 468 SQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPREGP 527
+ + A SP G SP G E +K P G + + GP
Sbjct: 309 ALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAG---EPSKAGPSGATAGASGRATGP 365
Query: 528 -AGGTGGSGGPGG 539
A G GG+GG GG
Sbjct: 366 EAAGGGGAGGGGG 378
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 129 bits (323), Expect = 4e-29
Identities = 218/896 (24%), Positives = 294/896 (32%), Gaps = 149/896 (16%)
Query: 1127 PPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPE 1186
P +P P SP+PPP V P+ + + + P +G G +T E +
Sbjct: 22 PGLLTPRPPGSPRPPPPVT-PAALRVLGAAGAVGRKPLAERAG--GIGGATIPESAPRAG 78
Query: 1187 PTGGGGGGGSSPSPAPAMSP----VPP----SPSPVPTPASPSGPATLDFTSQFGAALVG 1238
PT G +P+ P S PP SP PV +P SG Q G +
Sbjct: 79 PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 138
Query: 1239 AARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPY 1298
G EA +RS L S A + G T P P +
Sbjct: 139 EETVARGKATEAPKRSAL--SAGARRDTSGP----TPGTPSPAMAR-------------- 178
Query: 1299 LRLESAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGLALA 1358
R +AG+ G +R G S P P++ GL
Sbjct: 179 -RSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL--- 234
Query: 1359 ARERALKESSEGGGAPQPPPRPPSPRYEAPPPTPHHHS-PHAHHEPVLRLWGASPPDPAR 1417
+R S P P P P P H S P LR +PP R
Sbjct: 235 --QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP---R 289
Query: 1418 RELGYRAGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPW 1477
++ G S SP AA +S P P L QL T P P S P
Sbjct: 290 KDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPP 349
Query: 1478 R-SAAPEEPERLPLH---------VRFLENCQPRAPVTSGRGPPSEDGPGVP------PP 1521
P P P ++ + P P++ PP + P + PP
Sbjct: 350 SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP 409
Query: 1522 SPRRSVP------PSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSN 1575
SP S P PSP +P A + L PPP+P V F P PP+ S
Sbjct: 410 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP-----FSPPASPPVSPSA 464
Query: 1576 SFEKPESPLTPGPPHPLPDTPAPATPL------PPVPPPAVAAAP--------------- 1614
+ P PP +P +P + P+ PP PP +AA P
Sbjct: 465 TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALA 524
Query: 1615 -PTLDSTASSLTSYDSEV-----ATLTQGASAAPGDPHPP---------GPPAPAAPAPA 1659
P L + S S+ + A+L A P PP P PA+P
Sbjct: 525 TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ 584
Query: 1660 APQPGPDPPPGTD-SGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGV 1718
AP+ P P P T SG + + P + S +STLS G S+
Sbjct: 585 APRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSA--------- 635
Query: 1719 ASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGPSGGLRD 1778
S PE L Y + +G G +++P P P A+ P P R
Sbjct: 636 TSTPEELRGYDSGPEG---GAAASPPPDAELAACHP---------AAWSRGPAPPLAFRG 683
Query: 1779 PVTPTSPTVSVTGAGT-DGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKL 1837
P TG G+ DGL + GP +A A G + P P P S
Sbjct: 684 APGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGAL------DPGPSPGTSGGKAAA 737
Query: 1838 LPWEEGPGPPPPPLPGPLAQPQASALATVKASIISELSSKLQQFGGSSAAGGALPWARGG 1897
G G A+ L ++AS++ L S+ + A G GG
Sbjct: 738 -----GAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGG 792
Query: 1898 SGGGGDSHHGGASYV---------PERTSSLQRQRLSDDSQSSLLSKPVSSLFQNW 1944
+ GGG + GGA E S L R S S +S V+S +W
Sbjct: 793 AEGGGVT--GGARAALSDAELGRWAELLSPLDESRASITSVTSFSPDDVASPQGDW 846
Score = 85.9 bits (211), Expect = 4e-16
Identities = 215/840 (25%), Positives = 283/840 (33%), Gaps = 194/840 (23%)
Query: 1333 LPPRPLVHPLTGKALDPAS--PLGLALAARERALKESSEG-GGA--PQPPPR-------- 1379
L PRP P + PA+ LG A A + L E + G GGA P+ PR
Sbjct: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
Query: 1380 ----------PPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQ 1429
P S R E PP + SP P R G + P P LG +
Sbjct: 85 TSSRNPASRPPASGRGERAPPAKNT-SPGPVSSPG-RASGTTRPGP----------LGQK 132
Query: 1430 EKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLP 1489
+ A AR +A G G P P P +++ R+A E
Sbjct: 133 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG---- 188
Query: 1490 LHVRFLENCQPRAPVTSGRGPPSEDGP--GVPPPSPRRSVPPSPTSPRASEENGLPLLVL 1547
PR P S R P +GP V S + PSP + R G +
Sbjct: 189 ---------LPR-PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG---LQ 235
Query: 1548 PPPAPSVDVEDGEFLFVEPLPPPLEFSNSFE-KPESPLTPGPPHPLPDTPAPATPLPPVP 1606
P + S+ PL P S P +P P P P A P V
Sbjct: 236 RPASRSLSSS------ATPLSSPARSGPSARGTPRAPAHPSQPKP---KGLQALRPPQVT 286
Query: 1607 PPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPH------------PPGPPAPA 1654
PP AAP ++S L + A +Q P PH P PP+P+
Sbjct: 287 PPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPS 346
Query: 1655 APAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGA 1714
AP P P P + + + S L+ S LS
Sbjct: 347 APPSLQTLPSPPATPPSQA------TTSLGSPTLQATHSFLPSPPLSP------------ 388
Query: 1715 GAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLM---TPSKLRGRALGA---SGGL 1768
+A+ P +A QA P PP P L TPS AL
Sbjct: 389 ---LATPPPQAPPALALPPLQA-----PPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 440
Query: 1769 RPGPSGGLRDPVTP-TSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPL 1827
P PS ++ P +P SP VS + A PP+ +A P+ V P P P
Sbjct: 441 SPPPSPPVQAPFSPPASPPVSPS--------ATPPSQAPPS--LAAPPLQVPPSPPASPP 490
Query: 1828 PTASSLPRKLLPWEEGPGPPPPPLPGP---LAQPQASALATVKASIISELSSKLQQFGGS 1884
+ S+ P P PPPL P LA+P A + + L S F G
Sbjct: 491 MSPSATP---------PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQ 541
Query: 1885 S--AAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQRQRLSDDSQSSLLSKPVSSLFQ 1942
+ + +LP + A+ P+ L L S P S Q
Sbjct: 542 APFSPSASLPMSPL------------ATPPPQAPPVLAAPLLQVPP-----SPPASPTLQ 584
Query: 1943 NWPKPPLP-PLPTGTGVSPTAAAAPG-----ATSPSA----------SSSSTST-RHLQG 1985
+PP P P + +G T A APG + SPS+ SSS+TST L+G
Sbjct: 585 APRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRG 644
Query: 1986 VEFEMRPPLLRRAPSPSLLPASEHKV---SPAPRPSSLPILPSGPLY------PG----- 2031
+ P + L A PAP P + P PL PG
Sbjct: 645 YDSGPEGGAAASPPPDAELAACHPAAWSRGPAP-PLAFRGAPGAPLPWPPATGPGSADGL 703
Query: 2032 --LFDIRGSPTGG-AGGSADPFAPVFVPPHPGISGGLGGALSGA---SRSLSPTRLLSLP 2085
+++ G + A G+ DP P PG SGG A +GA SRS RL LP
Sbjct: 704 CTIYETEGPESATPAPGALDP------GPSPGTSGGKAAAGAGAGASSRSPKQARLGELP 757
Score = 72.8 bits (177), Expect = 3e-12
Identities = 162/646 (25%), Positives = 215/646 (33%), Gaps = 85/646 (13%)
Query: 1495 LENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSV-PPSPTSPRASEENGLPLLVLPPPAPS 1553
++N + +A + P+ PG+ P P S PP P +P A G V P
Sbjct: 1 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE 60
Query: 1554 VDVEDGEFLFVEPLP---PPLEFSNSFEKPES-PLTPGPPHPLPDTPAPATPLPPVPPPA 1609
G E P P S P S P G P PA T PV P
Sbjct: 61 RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAP--PAKNTSPGPVSSPG 118
Query: 1610 VAAAPPTLDSTASSLTSYDSEVATLTQGASAAP-------GDPHPPGPPAPAAPAPAAPQ 1662
A+ +E A+ AP G P P P+PA +
Sbjct: 119 RASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMAR 178
Query: 1663 PGPDPPPGTDSGI----EEVDSRSSSDHPLETISSAS----TLSSLSAEGGGSAGGGGGA 1714
GT+ G+ R ++ P +++SSAS T S +A SAGGG
Sbjct: 179 --RSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR 236
Query: 1715 GAGVASGPELLDTYVAYLDGQAFGGSSTPGPP-----------------YPPQLMTPSKL 1757
A L + L A G S G P PPQ+ P K
Sbjct: 237 PAS-----RSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKD 291
Query: 1758 RGRALG---ASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGL-----LALRACSGPPTA 1809
ALG +S P PS L+ PT P + + T L LA + S PP+
Sbjct: 292 AAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSL 351
Query: 1810 GVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLAQ-PQASALATVKA 1868
P P PP T+ P P PP PL P Q P A AL ++A
Sbjct: 352 QTLPSP----PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQA 407
Query: 1869 SIISELSSKLQQFG-GSSAAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQRQRLSDD 1927
S L S A AL H A + P + +Q
Sbjct: 408 PPSPPASPPLSPLATPSPQAPNALA-----------VHLLQAPFSPPPSPPVQAPFSPPA 456
Query: 1928 SQS-SLLSKPVSSLFQNWPKPPL---PPLPTGTGVSPTAAAAPGATSPSASSSSTSTRHL 1983
S S + P S + PPL P P +SP+A P A P A+ +
Sbjct: 457 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP 516
Query: 1984 QGVEFEMRPPLLRRAPSPSLLPASEHKVSPAPRPSSLPILPSGPLYPGLFDIRGSPTGGA 2043
+ P L+ PSP PAS +P +SLP+ P P + +P
Sbjct: 517 PQAPPALATPPLQALPSP---PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV 573
Query: 2044 GGSADPFAPVFVPPHPGISGGLGGALSGASRSLSPTRLLSLPPDKP 2089
S P +P P + G ++SG P L+L P P
Sbjct: 574 PPS-PPASPTLQAPRRPPTPGPDTSVSG------PRLTLALAPGPP 612
Score = 62.0 bits (149), Expect = 6e-09
Identities = 153/616 (24%), Positives = 198/616 (32%), Gaps = 124/616 (20%)
Query: 827 AAAQQTISASESPGPGGLASLGKHRP--KGFFATESSFDPHHRAQPS---YERPSFLPPG 881
A A+++ +A G A + RP +G + SS H +PS RPS G
Sbjct: 175 AMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPS---AG 231
Query: 882 PGLML---RQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPV 938
GL R S A P + P+ + + P P P PP TPP
Sbjct: 232 GGLQRPASRSLSSSATPLSSPARSGPSARGTPR--APAHPSQPKPKGLQALRPPQVTPP- 288
Query: 939 PSSSGRLTPSPRGGPFNPGSGGPLPASSP-ASFDGPSPPDTRVGSREKSL--YHSGPLP- 994
R +P GP S PL SP A+ +PP SL + PLP
Sbjct: 289 -----RKDAAPALGPL---SSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPL 340
Query: 995 --PAHHHPPHHHHHHAPPPQPHHH-------------HAHPPHPPEMETGGSPDDPPPRL 1039
P+ PP +PP P H+ P PP P PP L
Sbjct: 341 APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 400
Query: 1040 ALGPQPSLRGWRGGGPSPTPGAP-----SPSHHGSAGGGGGSSQGPALRYFQLPPRAASA 1094
AL P + PSP P +PS Q P F PP
Sbjct: 401 ALPPLQA-------PPSPPASPPLSPLATPSPQAPNALAVHLLQAP----FSPPPSPPVQ 449
Query: 1095 AMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPA------SPQPPPAVAAPS 1148
A + P S P PP+ +P S A P PP + P
Sbjct: 450 APFSPPAS----------------PPVSPSATPPSQAPPSLAAPPLQVPPSPP--ASPPM 491
Query: 1149 EKNSIPIPTI--IIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGS---SPSPAPA 1203
++ P P + AP + Q A PP Q P+ G SPS +
Sbjct: 492 SPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 551
Query: 1204 MSP------------------VPPSPSPVPTPASPSGPATLDFTSQFGAALVGAARREGG 1245
MSP VPPSP PT +P P T + + A G
Sbjct: 552 MSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP 611
Query: 1246 WQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLE-SA 1304
+R S ST +G + G T LR S EG +A P E +A
Sbjct: 612 PPPPSRSPS----STLSGPDLAGHSSSATSTP--EELRGYDSGPEGGAAASPPPDAELAA 665
Query: 1305 GSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERAL 1364
A + A A+ G G+ PL P A P S GL
Sbjct: 666 CHPAAWSRGPAPPLAFRGAPGA----------PLPWP---PATGPGSADGLCTIYETEGP 712
Query: 1365 KESSEGGGAPQPPPRP 1380
+ ++ GA P P P
Sbjct: 713 ESATPAPGALDPGPSP 728
Score = 59.7 bits (143), Expect = 3e-08
Identities = 98/389 (25%), Positives = 125/389 (32%), Gaps = 94/389 (24%)
Query: 890 SIGAAEDDR-PYLAPPAMKFSRSLSVPGSE-DIPPPPTTSPPEPPYSTP----------- 936
S GA D P P+ +R G+E +P P ++ P PP P
Sbjct: 157 SAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHS 216
Query: 937 -PVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPP 995
PS + R PS GG P S +++P S S P R P P
Sbjct: 217 TTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSAR----------GTPRAP 266
Query: 996 AHHHPPHHHHHHA-PPPQ--PHHHHAHPPHPPEMETGGSPDDP--------PPRLALGPQ 1044
AH P A PPQ P A P P + + P PP L P
Sbjct: 267 AHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPH 326
Query: 1045 PSLRGWRGGGP----SPTPGAP-----------SPSHHGSAGGGGGSSQG-------PAL 1082
S + P P+P AP +P + G + Q P L
Sbjct: 327 SSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPL 386
Query: 1083 RYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTS-------- 1134
PP A A+ +P PL P P+P +
Sbjct: 387 SPLATPPPQAPPALALP---------PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 437
Query: 1135 -PASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGG 1193
P SP P P V AP + P P + S+ SQ + A PP Q P
Sbjct: 438 APFSPPPSPPVQAPFSPPASP--------PVSPSATPPSQAPPSLAAPPLQVPP------ 483
Query: 1194 GGSSPSPAPAMSP--VPPSPSPVPTPASP 1220
SP +P MSP PP +P P A P
Sbjct: 484 ---SPPASPPMSPSATPPPQAPPPLAAPP 509
Score = 57.4 bits (137), Expect = 2e-07
Identities = 80/300 (26%), Positives = 106/300 (35%), Gaps = 50/300 (16%)
Query: 857 ATESSFDPHHRAQPSYERPSFLPPGPGLMLRQKSIGAAEDDRPYLAPPAMKFSR------ 910
AT S P A P + P P P + S P LA P ++ ++
Sbjct: 464 ATPPSQAPPSLAAPPLQVPPSPPASPPM---SPSATPPPQAPPPLAAPPLQLAKPPPQAP 520
Query: 911 -SLSVPGSEDIPPPPTTSPPEPPYSTPPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPAS 969
+L+ P + +P PP + P + P+S S TP P+ P +P S PAS
Sbjct: 521 PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 580
Query: 970 FDGPSP-------PDTRV-GSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHPP 1021
+P PDT V G R GP PP P + P H +
Sbjct: 581 PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP---SSTLSGPDLAGHSSSATS 637
Query: 1022 HPPEME------TGGSPDDPPPRLAL----------GPQPSLRGWRG--GGPSPTPGAPS 1063
P E+ GG+ PPP L GP P L +RG G P P P A
Sbjct: 638 TPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPL-AFRGAPGAPLPWPPATG 696
Query: 1064 PSHHGSAGG-------GGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKV 1116
P GSA G G S PA P ++ A +G G KQ ++
Sbjct: 697 P---GSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARL 753
Score = 49.3 bits (116), Expect = 4e-05
Identities = 87/344 (25%), Positives = 109/344 (31%), Gaps = 91/344 (26%)
Query: 937 PVPSSSGRLTPSPRGGPFNPGSGGP--LPASSPASFDGPSPPDTRVG-----SREKSLYH 989
P + G LTP P G P P P L A G P R G + +S
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
Query: 990 SGPL--------PPAHHHPPHHHHHHAPP--------------------PQPHHHHAHPP 1021
+GP PA P APP P P
Sbjct: 77 AGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI 136
Query: 1022 HPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPA 1081
E G + P R AL G R PTPG PSP+ G+ G
Sbjct: 137 SAEETVARGKATEAPKRSALS-----AGARRDTSGPTPGTPSPA-MARRSRAAGTEVG-- 188
Query: 1082 LRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVE------GEPQKGGGL--PPAPSPT 1133
LP A SA P R + + E P GGGL P + S +
Sbjct: 189 -----LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 243
Query: 1134 SPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGG 1193
S A+P PA SG S++G+ P+QP+P G
Sbjct: 244 SSATPLSSPA-----------------------RSGPSARGTPRAPAHPSQPKPKGLQAL 280
Query: 1194 GGSSPSP-----APAMSPVPPSPSPVPTP-------ASPSGPAT 1225
+P APA+ P+ SP P+P A P+ PAT
Sbjct: 281 RPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPAT 324
Score = 40.0 bits (92), Expect = 0.025
Identities = 48/155 (30%), Positives = 62/155 (40%), Gaps = 41/155 (26%)
Query: 421 RGPPGTGLTVPPALLRANSDTSMALPDW----MVFSAPGAASSGAPGPTSGSQGQSQPSA 476
RG PG L PPA ++D + + APGA PGP+ G
Sbjct: 682 RGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALD---PGPSPG--------- 729
Query: 477 PTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPR-----------E 525
+SG +A + GA +RSP + R E P G +S E
Sbjct: 730 -----TSGGKAAAGAGAGASSRSPKQARLGE----LPLGALQASVVQHLLSRTLLLAAAE 780
Query: 526 GPAGGTGGSGGPGGSLG---SRGRRRKLYSAVPGR 557
G AGG+G GGPGG+ G + G R L A GR
Sbjct: 781 GAAGGSG--GGPGGAEGGGVTGGARAALSDAELGR 813
Score = 33.5 bits (75), Expect = 2.3
Identities = 25/80 (31%), Positives = 33/80 (41%), Gaps = 6/80 (7%)
Query: 460 GAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRP-S 518
G P P ++ + P +SS + S + P A R PS G ++P R S
Sbjct: 188 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG----GGLQRPASRSLS 243
Query: 519 SSGTPREGPA-GGTGGSGGP 537
SS TP PA G G P
Sbjct: 244 SSATPLSSPARSGPSARGTP 263
Score = 32.0 bits (71), Expect = 6.8
Identities = 31/117 (26%), Positives = 45/117 (38%), Gaps = 8/117 (6%)
Query: 413 SPKYAARRRGPPGTGLTV--PPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQG 470
+P+ A P GL PP + D + AL + S+P A P P++ Q
Sbjct: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP--LSSSPLAT----PSPSAALQS 315
Query: 471 QSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPREGP 527
Q+ P+ P T SS ++P SPS + P PS + T P
Sbjct: 316 QAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSP 372
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 126 bits (317), Expect = 2e-28
Identities = 226/877 (25%), Positives = 300/877 (34%), Gaps = 150/877 (17%)
Query: 1127 PPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPE 1186
P +P P SP+PPP V P+ + + + P +G + E+ P P
Sbjct: 22 PGLLTPRPPGSPRPPPPVT-PAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT 80
Query: 1187 PTGGGGGGGSSPSPAPAMSPVPPSPSPVPTPASPSGPATLDFTSQFGAALVGAARREGGW 1246
T G PA + SP PV +P SG Q G + G
Sbjct: 81 RTSRPPASGRGERAPPAKNT---SPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGK 137
Query: 1247 QNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLR------ 1300
EA +RS L S A + G GT + R + + G+ P R
Sbjct: 138 ATEAPKRSAL--SAGARRDTSGPTP-GTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE 194
Query: 1301 -----LESAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGL 1355
+ SA + A R GGG RP L+ A +SP
Sbjct: 195 GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ--------RPASRSLSSSATPLSSPARS 246
Query: 1356 ALAAR--ERALKESSE----GGGAPQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWG 1409
+AR RA S+ G A +PP P + AP P SP A P
Sbjct: 247 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP------ 300
Query: 1410 ASPPDPARRELGYRAGLGSQE-KSLPASPPAARRSLL--------HRLPPTAPGVGPLLL 1460
++PP P+ A Q S PA+PP+ + L H P+ P L
Sbjct: 301 SAPPSPS-------APPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP-----LS 348
Query: 1461 QLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPP 1520
L T PP P ++ P A P P PL L P+AP + P PP
Sbjct: 349 PLATPPPQAPPALALPPLQAPPSPPASPPLSP--LATPSPQAP--NALAVHLLQAPFSPP 404
Query: 1521 PSPRRSVPPSP-----TSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSN 1575
PSP P SP SP A+ + P + PP L V P PP
Sbjct: 405 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP-----------LQVPPSPPA----- 448
Query: 1576 SFEKPESPLTPGPPHPLPDTPAPATPL---PPVPPPAVAAAPPTLDSTASSLTSYDSEV- 1631
P SP PP P AP L PP PPA+A P L + S S+ +
Sbjct: 449 --SPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPP--LQALPSPPASFPGQAP 504
Query: 1632 ----ATLTQGASAAPGDPHPP---------GPPAPAAPAPAAPQPGPDPPPGTD-SGIEE 1677
A+L A P PP P PA+P AP+ P P P T SG
Sbjct: 505 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL 564
Query: 1678 VDSRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAF 1737
+ + P + S +STLS G S+ S PE L Y + +G
Sbjct: 565 TLALAPGPPPPPSRSPSSTLSGPDLAGHSSSA---------TSTPEELRGYDSGPEG--- 612
Query: 1738 GGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGT-DG 1796
G +++P P P A+ P P R P TG G+ DG
Sbjct: 613 GAAASPPPDAELAACHP---------AAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADG 663
Query: 1797 LLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLA 1856
L + GP +A A G + P P P S G G A
Sbjct: 664 LCTIYETEGPESATPAPGAL------DPGPSPGTSGGKAAA-----GAGAGASSRSPKQA 712
Query: 1857 QPQASALATVKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYV---- 1912
+ L ++AS++ L S+ + A G GG+ GGG + GGA
Sbjct: 713 RLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVT--GGARAALSDA 770
Query: 1913 -----PERTSSLQRQRLSDDSQSSLLSKPVSSLFQNW 1944
E S L R S S +S V+S +W
Sbjct: 771 ELGRWAELLSPLDESRASITSVTSFSPDDVASPQGDW 807
Score = 87.4 bits (215), Expect = 1e-16
Identities = 214/855 (25%), Positives = 272/855 (31%), Gaps = 179/855 (20%)
Query: 937 PVPSSSGRLTPSPRGGPFNPGSGGP--LPASSPASFDGPSPPDTRVG-----SREKSLYH 989
P + G LTP P G P P P L A G P R G + +S
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
Query: 990 SGPL----PPA----HHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETG-----------G 1030
+GP PPA PP + P P P + G G
Sbjct: 77 AGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARG 136
Query: 1031 SPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPR 1090
+ P R AL G R PTPG PSP+ G+ G LP
Sbjct: 137 KATEAPKRSALS-----AGARRDTSGPTPGTPSPA-MARRSRAAGTEVG-------LPRP 183
Query: 1091 AASAAMYVPARSGRGRKGPLVKQTKVE------GEPQKGGGL--PPAPSPTSPASPQPPP 1142
A SA P R + + E P GGGL P + S +S A+P P
Sbjct: 184 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 243
Query: 1143 AVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAP 1202
A + PS + + +AP+ S + + T P G S SP
Sbjct: 244 ARSGPSARGT-------PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA 296
Query: 1203 AMSP-VPPSPSPVPT-------PASPSGPATLDF---TSQFGAALVGAARREGGWQNEAR 1251
SP PPSPS P+ PA+P AT T Q + + + +
Sbjct: 297 TPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQ 356
Query: 1252 RRSTLFL-STDAGDEDGGDGGLGTGAAPGPRLRHSKSID--EGMFSAEPYLRLESAGSGA 1308
L L A L A P P+ ++ ++ + FS P +++ S
Sbjct: 357 APPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS-- 414
Query: 1309 GYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKESS 1368
A S+ S PP PL PASP S
Sbjct: 415 --------PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP------------PMSP 454
Query: 1369 EGGGAPQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGS 1428
PQ PP +P + P P +P A P L+ SPP + + S
Sbjct: 455 SATPPPQAPPPLAAPPLQLAKPPP--QAPPALATPPLQAL-PSPPASFPGQAPF-----S 506
Query: 1429 QEKSLPASPPAARRSLLHRLPPTAPGV-GPLLLQLGTEPPAPHPGVSKPWRSAAPEEPER 1487
SLP SP A PP AP V LLQ+ PPA P + P R P
Sbjct: 507 PSASLPMSPLATP-------PPQAPPVLAAPLLQVPPSPPA-SPTLQAPRRPPTP----- 553
Query: 1488 LPLHVRFLENCQPRAPVTSGRGP--PSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLL 1545
P TS GP PG PPP P RS P S S +
Sbjct: 554 --------------GPDTSVSGPRLTLALAPG-PPPPPSRS-PSSTLSGPDLAGHSSSAT 597
Query: 1546 VLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPV 1605
P D P PP E + + + GP PL AP PLP
Sbjct: 598 STPEELRGYDSGPEGGAAASP-PPDAELAACH---PAAWSRGPAPPLAFRGAPGAPLPWP 653
Query: 1606 PPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGP 1665
P A P + D T Y++E P A PAP A PGP
Sbjct: 654 P----ATGPGSADGLC---TIYETE-------------------GPESATPAPGALDPGP 687
Query: 1666 DPPPGTDSGIEEVDSRSSSDHPLET------------------ISSASTLSSLSAEGGGS 1707
P + +SS P + +S L++ GGS
Sbjct: 688 SPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGS 747
Query: 1708 AGGGGGA-GAGVASG 1721
GG GGA G GV G
Sbjct: 748 GGGPGGAEGGGVTGG 762
Score = 84.3 bits (207), Expect = 1e-15
Identities = 211/813 (25%), Positives = 275/813 (33%), Gaps = 179/813 (22%)
Query: 1333 LPPRPLVHPLTGKALDPAS--PLGLALAARERALKESSEG-GGA--PQPPPRPPSPRYEA 1387
L PRP P + PA+ LG A A + L E + G GGA P+ PR R
Sbjct: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSR 84
Query: 1388 PPPTPHHHSPHAHHEPVLRLWGASP-PDPARRELGYRAG-LGSQEKSLPASPPAARRSLL 1445
PP S P + P P R R G LG + + A AR
Sbjct: 85 PPA-----SGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKAT 139
Query: 1446 HRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPRAPVT 1505
+A G G P P P +++ R+A E PR P
Sbjct: 140 EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG-------------LPR-PAP 185
Query: 1506 SGRGPPSEDGP--GVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLF 1563
S R P +GP V S + PSP + R G L PA
Sbjct: 186 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG----GLQRPASR---------- 231
Query: 1564 VEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTP-APATPLPPVPPPAVAAAPPTLDSTAS 1622
S+S SP GP TP APA P P P A PP
Sbjct: 232 --------SLSSSATPLSSPARSGPS--ARGTPRAPAHPSQPKPKGLQALRPP------- 274
Query: 1623 SLTSYDSEVATLTQGASAAP-GDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSR 1681
+T + A S++P P P PP+P+AP P P P + + +
Sbjct: 275 QVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQA------TT 328
Query: 1682 SSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGSS 1741
S L+ S LS +A+ P +A QA
Sbjct: 329 SLGSPTLQATHSFLPSPPLSP---------------LATPPPQAPPALALPPLQA----- 368
Query: 1742 TPGPPYPPQLM---TPSKLRGRALGA---SGGLRPGPSGGLRDPVTP-TSPTVSVTGAGT 1794
P PP P L TPS AL P PS ++ P +P SP VS +
Sbjct: 369 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS---- 424
Query: 1795 DGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGP 1854
A PP+ +A P+ V P P P + S+ P P PPPL P
Sbjct: 425 ----ATPPSQAPPS--LAAPPLQVPPSPPASPPMSPSATP---------PPQAPPPLAAP 469
Query: 1855 ---LAQPQASALATVKASIISELSSKLQQFGGSS--AAGGALPWARGGSGGGGDSHHGGA 1909
LA+P A + + L S F G + + +LP + A
Sbjct: 470 PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL------------A 517
Query: 1910 SYVPERTSSLQRQRLSDDSQSSLLSKPVSSLFQNWPKPPLP-PLPTGTGVSPTAAAAPG- 1967
+ P+ L L S P S Q +PP P P + +G T A APG
Sbjct: 518 TPPPQAPPVLAAPLLQVPP-----SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP 572
Query: 1968 ----ATSPSA----------SSSSTST-RHLQGVEFEMRPPLLRRAPSPSLLPASEHKV- 2011
+ SPS+ SSS+TST L+G + P + L A
Sbjct: 573 PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW 632
Query: 2012 --SPAPRPSSLPILPSGPLY------PG-------LFDIRGSPTGG-AGGSADPFAPVFV 2055
PAP P + P PL PG +++ G + A G+ DP
Sbjct: 633 SRGPAP-PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDP------ 685
Query: 2056 PPHPGISGGLGGALSGA---SRSLSPTRLLSLP 2085
P PG SGG A +GA SRS RL LP
Sbjct: 686 GPSPGTSGGKAAAGAGAGASSRSPKQARLGELP 718
Score = 74.7 bits (182), Expect = 9e-13
Identities = 148/582 (25%), Positives = 197/582 (33%), Gaps = 86/582 (14%)
Query: 827 AAAQQTISASESPGPGGLASLGKHRP--KGFFATESSFDPHHRAQPS---YERPSFLPPG 881
A A+++ +A G A + RP +G + SS H +PS RPS G
Sbjct: 166 AMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPS---AG 222
Query: 882 PGLML---RQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPV 938
GL R S A P + P+ + + P P P PP TPP
Sbjct: 223 GGLQRPASRSLSSSATPLSSPARSGPSARGTPR--APAHPSQPKPKGLQALRPPQVTPP- 279
Query: 939 PSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHH 998
R +P GP S PL SP++ PS P + + P PPA
Sbjct: 280 -----RKDAAPALGPL---SSSPLATPSPSAPPSPSAPPS---------LQTLPSPPA-- 320
Query: 999 HPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPT 1058
PP P H+ P PP P PP LAL P + PSP
Sbjct: 321 TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQA-------PPSPP 373
Query: 1059 PGAP-SPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARS---GRGRKGPLVKQT 1114
P SP S + F PP A + P S P
Sbjct: 374 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 433
Query: 1115 KVEGEPQKGGGLPPAPSPTSPAS---PQPPPAVAAPSEKNSIPIPTI----------IIK 1161
+ P + PPA P SP++ PQ PP +AAP + + P P +
Sbjct: 434 SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP 493
Query: 1162 APSTSSSGRS--SQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPSPVPTPAS 1219
+P S G++ S +S P P P + P A + VPPSP PT +
Sbjct: 494 SPPASFPGQAPFSPSASLPMSPLATPPPQ-------APPVLAAPLLQVPPSPPASPTLQA 546
Query: 1220 PSGPATLDFTSQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPG 1279
P P T + + A G +R S ST +G + G T
Sbjct: 547 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS----STLSGPDLAGHSSSATSTP-- 600
Query: 1280 PRLRHSKSIDEGMFSAEPYLRLE-SAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPL 1338
LR S EG +A P E +A A + A A+ G G+ PL
Sbjct: 601 EELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGA----------PL 650
Query: 1339 VHPLTGKALDPASPLGLALAARERALKESSEGGGAPQPPPRP 1380
P A P S GL + ++ GA P P P
Sbjct: 651 PWP---PATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 689
Score = 66.6 bits (161), Expect = 2e-10
Identities = 153/622 (24%), Positives = 212/622 (34%), Gaps = 76/622 (12%)
Query: 1495 LENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSV-PPSPTSPRASEENGLPLLVLPPPAPS 1553
++N + +A + P+ PG+ P P S PP P +P A G V P
Sbjct: 1 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE 60
Query: 1554 VDVEDGEFLFVEPLP---------PPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPP 1604
G E P PP P +PGP P + T P
Sbjct: 61 RAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSS-PGRASGTTRPGP 119
Query: 1605 VPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGP-PAPAAPAPAA--- 1660
+ + + ++ A + + + L+ GA P P P PA A + AA
Sbjct: 120 LGQKGLRISAE--ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 177
Query: 1661 ---PQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSAS----TLSSLSAEGGGSAGGGGG 1713
P+P P P R ++ P +++SSAS T S +A SAGGG
Sbjct: 178 VGLPRPAPSARP-----------RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ 226
Query: 1714 AGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGPS 1773
A L + L A G S G P P PS+ + + L A LRP
Sbjct: 227 RPAS-----RSLSSSATPLSSPARSGPSARGTPRAP--AHPSQPKPKGLQA---LRPPQV 276
Query: 1774 GGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSL 1833
R P +S + T A + S PP+ P P PP T+
Sbjct: 277 TPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSP----PATPPSQATTSLGS 332
Query: 1834 PRKLLPWEEGPGPPPPPLPGPLAQ-PQASALATVKASIISELSSKLQQFG-GSSAAGGAL 1891
P P PP PL P Q P A AL ++A S L S A AL
Sbjct: 333 PTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNAL 392
Query: 1892 PWARGGSGGGGDSHHGGASYVPERTSSLQRQRLSDDSQS-SLLSKPVSSLFQNWPKPPL- 1949
H A + P + +Q S S + P S + PPL
Sbjct: 393 A-----------VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 441
Query: 1950 --PPLPTGTGVSPTAAAAPGATSPSASSSSTSTRHLQGVEFEMRPPLLRRAPSPSLLPAS 2007
P P +SP+A P A P A+ + + P L+ PSP PAS
Sbjct: 442 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP---PAS 498
Query: 2008 EHKVSPAPRPSSLPILPSGPLYPGLFDIRGSPTGGAGGSADPFAPVFVPPHPGISGGLGG 2067
+P +SLP+ P P + +P S P +P P + G
Sbjct: 499 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS-PPASPTLQAPRRPPTPGPDT 557
Query: 2068 ALSGASRSLSPTRLLSLPPDKP 2089
++SG P L+L P P
Sbjct: 558 SVSG------PRLTLALAPGPP 573
Score = 63.9 bits (154), Expect = 2e-09
Identities = 151/600 (25%), Positives = 196/600 (32%), Gaps = 135/600 (22%)
Query: 771 PQQAKRLPPPTISLRSKSMTSELEEMEYEQQPAPVPSMEKKRTVYQMALNKLDEILAAAQ 830
P+ + L PP ++ K L + P PS +
Sbjct: 265 PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPS 324
Query: 831 QTISASESPGPGGLASLGKHRPKGFFATESSFDPHHRAQPSYERPSFLPPGPGLMLRQKS 890
Q ++ SP S P AT P A P + P P P L
Sbjct: 325 QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSP---- 380
Query: 891 IGAAEDDRPYLAPPAMKFSRSLSV-----PGSEDIPPPPTTSPPEPPYSTPPVPSSSGRL 945
LA P+ + +L+V P S P PP +P PP S PPV S+
Sbjct: 381 ----------LATPSPQAPNALAVHLLQAPFSPP-PSPPVQAPFSPPAS-PPVSPSA--- 425
Query: 946 TPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHH 1005
P S P ++P PSPP S P+ P+ PP
Sbjct: 426 ---------TPPSQAPPSLAAPPLQVPPSPP------------ASPPMSPSATPPP---- 460
Query: 1006 HHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPS 1065
APPP A PP ++ P PP LA P +L P P +PS S
Sbjct: 461 -QAPPPL-----AAPP----LQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 510
Query: 1066 HHGSAGGGGGSSQGPALR--YFQLPPR-AASAAMYVPARSGRGRKGPLVKQTKVEGEPQK 1122
S P L Q+PP AS + P R GP T V G P+
Sbjct: 511 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP--PTPGP---DTSVSG-PRL 564
Query: 1123 GGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPP 1182
L P P PPP +PS S P +G SS +ST E
Sbjct: 565 TLALAPGP---------PPPPSRSPSSTLSGP-----------DLAGHSSSATSTPEE-- 602
Query: 1183 TQPEPTGGGGGGGSSPSP----------APAMSPVPP------SPSPVPTPASPSGPATL 1226
+ +G GG +SP P A + P PP +P+P P + +GP +
Sbjct: 603 LRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPA-TGPGSA 661
Query: 1227 DFTSQFGAALVGAARREGGWQNEARRRSTLFL-STDAGDEDGGDGG---LGTGAAPGPRL 1282
D G + ++ E +T + D G G GG G GA R
Sbjct: 662 D-----GLCTI--------YETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRS 708
Query: 1283 RHSKSIDE---GMFSAEPYLRLES------AGSGAGYGGYGAGSRAYGGG--GGSSAFTS 1331
+ E G A L S A GA G G A GGG GG+ A S
Sbjct: 709 PKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAALS 768
Score = 40.0 bits (92), Expect = 0.025
Identities = 48/155 (30%), Positives = 62/155 (40%), Gaps = 41/155 (26%)
Query: 421 RGPPGTGLTVPPALLRANSDTSMALPDW----MVFSAPGAASSGAPGPTSGSQGQSQPSA 476
RG PG L PPA ++D + + APGA PGP+ G
Sbjct: 643 RGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALD---PGPSPG--------- 690
Query: 477 PTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPR-----------E 525
+SG +A + GA +RSP + R E P G +S E
Sbjct: 691 -----TSGGKAAAGAGAGASSRSPKQARLGE----LPLGALQASVVQHLLSRTLLLAAAE 741
Query: 526 GPAGGTGGSGGPGGSLG---SRGRRRKLYSAVPGR 557
G AGG+G GGPGG+ G + G R L A GR
Sbjct: 742 GAAGGSG--GGPGGAEGGGVTGGARAALSDAELGR 774
Score = 33.5 bits (75), Expect = 2.3
Identities = 25/80 (31%), Positives = 33/80 (41%), Gaps = 6/80 (7%)
Query: 460 GAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRP-S 518
G P P ++ + P +SS + S + P A R PS G ++P R S
Sbjct: 179 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG----GGLQRPASRSLS 234
Query: 519 SSGTPREGPA-GGTGGSGGP 537
SS TP PA G G P
Sbjct: 235 SSATPLSSPARSGPSARGTP 254
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 125 bits (313), Expect = 6e-28
Identities = 317/1268 (25%), Positives = 391/1268 (30%), Gaps = 244/1268 (19%)
Query: 896 DDRPYLAP-PAMKFSRSLSVPGSEDIPP--PPTTSPPEPPYSTPPVPSSSGRL-TPSPRG 951
DD+ P P + F +V P PP P+ P P P GR P G
Sbjct: 68 DDQELDCPNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPG 127
Query: 952 GPFNPGSGGP--LPASSPASFDGPSPP----DTRVGSREKSLY-HSGPL-PPAHHHPPHH 1003
P +PGS GP + S P SP D + G L + GP PP PP
Sbjct: 128 QPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGT 187
Query: 1004 HHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGP-----------QPSLRGWRG 1052
H P P + PP P P PP A+GP +P G RG
Sbjct: 188 SGHPGSPGSPGYQ--GPPGEPGQAGPSGPPGPPG--AIGPSGPAGKDGESGRPGRPGERG 243
Query: 1053 -------GGPSPTPGAPS-PSHHGSAGGGG--GSSQGPALRYFQLPPRAASAAMYVPARS 1102
GP+ PG P H G G G G + P L+ P A + R
Sbjct: 244 LPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRG 303
Query: 1103 GRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKA 1162
G +G + + G G S P P PP P + + A
Sbjct: 304 APGERG----RPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGA---KGEVGPA 356
Query: 1163 PSTSSSG----RSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPSPVPTPA 1218
S S+G R G A P P G G G PA P P P
Sbjct: 357 GSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPP 416
Query: 1219 SPSGP-ATLDFTSQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAA 1277
P+G G A+ E G + E R + + A EDG DG G A
Sbjct: 417 GPAGANGAPGLRGGAGEPGKNGAKGEPGPRGE-RGEAGIPGVPGAKGEDGKDGSPGEPGA 475
Query: 1278 PG-PRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYG-AGSRAYGGGGGSSAFTSFLPP 1335
G P + A P G G G AG R G G +P
Sbjct: 476 NGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDG----VPG 531
Query: 1336 RPLVHPLTGKALDPASPLGLALAARERALKESSEGGGAPQPPPRPPSPRYEAPPPTPHHH 1395
P + + G S GG P PP + E+ P P
Sbjct: 532 GPGMRGMPG-----------------------SPGGPGSDGKPGPPGSQGESGRPGPPGP 568
Query: 1396 SPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAARRSLLHRLPPTAPGV 1455
S V+ G D A + G R G G P PP + PP G
Sbjct: 569 SGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPG---PQGPPGKNGETGPQGPPGPTGP 625
Query: 1456 GPLLLQLGTEPPAPH-----PGV-SKPWRSAAPEEPERLPLHVRFLENCQPRAPVTSG-R 1508
G + T PP P PG P + P EP + P AP G
Sbjct: 626 GG--DKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKG------DAGAPGAPGGKGDA 677
Query: 1509 GPPSEDGP-----------GVPPPSPR----RSVPPSPTSPRASEENGLPLLV-----LP 1548
G P E GP G PP P + PP P P A+ GL + L
Sbjct: 678 GAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGP--PGAAGTPGLQGMPGERGGLG 735
Query: 1549 PPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPP 1608
P P D GE P P G +P P P P+ PP
Sbjct: 736 SPGPKGD--KGE-------------------PGGPGADG----VPGKDGPRGPTGPIGPP 770
Query: 1609 AVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPP 1668
A P +G APG P GP PGP
Sbjct: 771 GPAGQPG-------------------DKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGF 811
Query: 1669 PGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGG--GSAGGGGGAGAGVASGPELLD 1726
PG E + P E EGG G AG GG+G GP+ +
Sbjct: 812 PGAPGQNGEPGGKGERGAPGE-----------KGEGGPPGVAGPPGGSGPAGPPGPQGVK 860
Query: 1727 TYVAYLDGQAF----GGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGPSGGLRDPVT- 1781
G G PGPP G++G PGP G P
Sbjct: 861 GERGSPGGPGAAGFPGARGLPGPP----------------GSNG--NPGPPGPSGSPGKD 902
Query: 1782 -PTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPW 1840
P P + G+ G+ + +G P G G P A P P PL A + L
Sbjct: 903 GPPGPAGNTGAPGSPGVSGPKGDAGQP--GEKGSPGAQGPPGAPGPLGIAGITGARGL-- 958
Query: 1841 EEGPGPPPPPLPGPLAQPQASALATVKASIISELSSKLQQFGGSSAAGGALPWARGGSGG 1900
PP +PGP P VK ++ L G G LP G +G
Sbjct: 959 -----AGPPGMPGPRGSPGPQG---VKGESGKPGANGLSGERGPPGPQG-LPGLAGTAGE 1009
Query: 1901 GGDSHHGGASYVPERTSSLQRQRLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPTG----- 1955
G + G+ +P R S + ++ S P + P PP P P G
Sbjct: 1010 PGRDGNPGSDGLPGRDGSPGGKGDRGENGS-----PGAPGAPGHPGPPGPVGPAGKSGDR 1064
Query: 1956 --TGVSPTAAA--------APGATSPSASSSSTSTRHLQGVEFEMRPPLLRRAP-SPSLL 2004
+G + A A APG P T R G++ P AP SP
Sbjct: 1065 GESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPG-- 1122
Query: 2005 PASEHKV--SPAPRPSSLPILPSGPLYPGLFDIRGSP----TGGAGGSADPFAPVFVPPH 2058
PA + SP P P+ PSGP PG G P G G+ P H
Sbjct: 1123 PAGQQGAIGSPGPAGPRGPVGPSGP--PGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGH 1180
Query: 2059 PGISGGLG 2066
PG G G
Sbjct: 1181 PGQPGPPG 1188
Score = 108 bits (270), Expect = 6e-23
Identities = 283/1148 (24%), Positives = 333/1148 (29%), Gaps = 260/1148 (22%)
Query: 1021 PHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPS-PSHHGSAG--GGGGSS 1077
P PP +P PP GPQ GP PG P P +G G G GS
Sbjct: 89 PQPPT-----APTRPPN--GQGPQ---------GPKGDPGPPGIPGRNGDPGIPGQPGSP 132
Query: 1078 QGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPAS 1137
P PP + P VK G GL P P P
Sbjct: 133 GSPG------PPGICESCPTGPQNYSPQYDSYDVKSGVAVG------GLAGYPGPAGPPG 180
Query: 1138 PQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSS 1197
P PP + P + G +A P P P G G G +
Sbjct: 181 PPGPPGTSGHPGSPGSP-------------GYQGPPGEPGQAGPSGPPGPPGAIGPSGPA 227
Query: 1198 PSPAPAMSPVPPSPSPVPTPASPSGPATLDFTSQFGAALVGAARREGGWQNEARRRSTLF 1257
+ P P +P P GPA + G + R G E
Sbjct: 228 GKDGESGRPGRPGERGLPGPPGIKGPAGIP-----GFPGMKGHRGFDGRNGEKGETGAPG 282
Query: 1258 LSTDAG--DEDGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGA 1315
L + G E+G G +G APG R R G G A
Sbjct: 283 LKGENGLPGENGAPGPMGPRGAPGERGR------------------------PGLPG-AA 317
Query: 1316 GSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKESSEGGGAPQ 1375
G+R G GS PP P G A P SP ++G P
Sbjct: 318 GARGNDGARGSDGQPG--PPGP-----PGTAGFPGSP--------------GAKGEVGPA 356
Query: 1376 PPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPA 1435
P + P P H+ PP P G G + + PA
Sbjct: 357 GSPGSNGAPGQRGEPGPQGHAG-----------AQGPPGPP----GINGSPGGKGEMGPA 401
Query: 1436 SPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFL 1495
P A + R PP G P G +P ++ A EP P R
Sbjct: 402 GIPGAPGLMGARGPPGPAGANGA--------PGLRGGAGEPGKNGAKGEPG--PRGERG- 450
Query: 1496 ENCQPRAPVTSGR----GPPSEDGP-GVPPPSPRRSVPP--SPTSPRA-------SEENG 1541
E P P G G P E G G+P + R P P P + E G
Sbjct: 451 EAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERG 510
Query: 1542 LPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATP 1601
P P A DG V P S P S PGPP ++ P P
Sbjct: 511 APGPAGPRGAAGEPGRDG----VPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPP 566
Query: 1602 LPPVP--PPAVAA--APPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPA 1657
P P P V P D QG G+ P GPP P P
Sbjct: 567 GPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPG 626
Query: 1658 -------PAAPQ-----PGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGG 1705
P PQ PG PPG + E + + P
Sbjct: 627 GDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAP------------------ 668
Query: 1706 GSAGGGGGAGAGVASGPELLDTYVAYLDGQA----FGGSSTPGPPYPPQLMTPSKLRGRA 1761
G+ GG G AGA GP L G GG GPP PP L+G
Sbjct: 669 GAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMP 728
Query: 1762 LGASGGL-RPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGP----V 1816
G GGL PGP G +P P + V G DG GPP G AG P
Sbjct: 729 -GERGGLGSPGPKGDKGEPGGPGADGV----PGKDGPRGPTGPIGPP--GPAGQPGDKGE 781
Query: 1817 AVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLAQPQASALATVKASIISELSS 1876
P +P + P S P E G PP P P A Q E
Sbjct: 782 GGAPGLPGIAGPRGS-------PGERGETGPPGPAGFPGAPGQN-----------GEPGG 823
Query: 1877 KLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQRQRLSDDSQSSLLSKP 1936
K ++ G P G GG G + G V S + + L P
Sbjct: 824 KGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGP 883
Query: 1937 VSSLFQNWPKPPL-------PPLPTG-TGV--------------------SPTAAAAPGA 1968
S P P PP P G TG SP A PGA
Sbjct: 884 PGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGA 943
Query: 1969 TSPSASSSSTSTRHLQGVEFEMRPPLLRRAPSPSLLPASEHKVSP--------APRPSSL 2020
P + T R L G P R +P P + K P P L
Sbjct: 944 PGPLGIAGITGARGLAGPPGMPGP---RGSPGPQGVKGESGKPGANGLSGERGPPGPQGL 1000
Query: 2021 PIL---------PSGPLYPGLFDIRGSP--TGGAGGSADPFAPVFVPPHPGISGGLGGAL 2069
P L P GL GSP G G + P AP P HPG G +G A
Sbjct: 1001 PGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAP-GAPGHPGPPGPVGPAG 1059
Query: 2070 SGASRSLS 2077
R S
Sbjct: 1060 KSGDRGES 1067
Score = 105 bits (263), Expect = 4e-22
Identities = 255/1049 (24%), Positives = 325/1049 (30%), Gaps = 204/1049 (19%)
Query: 870 PSYERPSFLPPGPGLMLRQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPP--PTTS 927
P + P+ +P PG M + ++ P +K L PG P P P +
Sbjct: 248 PGIKGPAGIPGFPG-MKGHRGFDGRNGEKGETGAPGLKGENGL--PGENGAPGPMGPRGA 304
Query: 928 PPEPPYSTPPVPSSSG-RLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKS 986
P E P +P ++G R RG PG GP P + P P +
Sbjct: 305 PGER--GRPGLPGAAGARGNDGARGSDGQPGPPGP-----PGTAGFPGSPGAKGEVGPAG 357
Query: 987 LYHSGPLPPAHHHP-PHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQ- 1044
S P P P H PP P + P EM G P P A GP
Sbjct: 358 SPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPG 417
Query: 1045 -------PSLRGWRG--------GGPSPT--------PGAP----------SPSHHGSAG 1071
P LRG G G P P PG P SP G+ G
Sbjct: 418 PAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANG 477
Query: 1072 GGGGSSQGPALRYFQLPPRAASAAMYVPARSG----RGRKGPLVKQTKVEGEPQKGG--- 1124
G + + A + R + +P G RG GP + GEP + G
Sbjct: 478 LPGAAGERGAPGF-----RGPAGPNGIPGEKGPAGERGAPGPAGPRGAA-GEPGRDGVPG 531
Query: 1125 -----GLPPAPS-PTSPASPQPP-----------PAVAAPSEKNSI---PIPTIIIKAPS 1164
G+P +P P S P PP P + P + + P P AP
Sbjct: 532 GPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPG 591
Query: 1165 TSSSG--------RSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAP-AMSPVPPSPSPVP 1215
+ + G + E P P PTG GG G + P P + +P + P
Sbjct: 592 KNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPG 651
Query: 1216 TPASPSGPATLDFTSQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTG 1275
P P GA G + L AG G +GG G
Sbjct: 652 ENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPP-GPEGGKGAA 710
Query: 1276 AAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGA-GSRAYGGGGGSSAFTSFLP 1334
PGP +GM G G G G G + GG G+
Sbjct: 711 GPPGPPGAAGTPGLQGM-----------PGERGGLGSPGPKGDKGEPGGPGADGVPGKDG 759
Query: 1335 PRPLVHPLTGKALDPASPLGLALAARERALKESSEGGGAPQP----PPRPPSPRYEAPPP 1390
PR P+ P P G + EGG P P P R E PP
Sbjct: 760 PRGPTGPI-----GPPGPAGQP--------GDKGEGGAPGLPGIAGPRGSPGERGETGPP 806
Query: 1391 TPHHH--SPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAARRSLLHRL 1448
P +P + EP + +P + + E G G S PA PP + R
Sbjct: 807 GPAGFPGAPGQNGEPGGKGERGAPGE--KGEGGPPGVAGPPGGSGPAGPPGPQGVKGERG 864
Query: 1449 PPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPRAPVTSGR 1508
P PG G P PG N P P SG
Sbjct: 865 SPGGPGAAGFPGARGLPGP---PG-----------------------SNGNPGPPGPSGS 898
Query: 1509 GPPSEDGPGVPPPSPRRSVPPSP--TSPRASE----ENGLPLLVLPPPAPSVDVEDGEFL 1562
P +DGP P P+ P SP + P+ E G P PP AP L
Sbjct: 899 --PGKDGP--PGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGP-------L 947
Query: 1563 FVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPAT--------PLPPVPPPAVA--A 1612
+ + + P +PGP ++ P P P P +A A
Sbjct: 948 GIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTA 1007
Query: 1613 APPTLDSTASS--LTSYDSEVATL----TQGASAAPGDPHPPGPPAPAAPAPAAPQPGPD 1666
P D S L D G+ APG P PGPP P PA + G
Sbjct: 1008 GEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGES 1067
Query: 1667 PPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLD 1726
P G SR + T +A G G G GA + GP
Sbjct: 1068 GPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPA--- 1124
Query: 1727 TYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPT 1786
GQ G +PGP P + PS G+ G SG PGP G P P
Sbjct: 1125 -------GQQ-GAIGSPGPAGPRGPVGPSGPPGKD-GTSG--HPGPIG-------PPGPR 1166
Query: 1787 VSVTGAGTDGLLALRACSGPPTAGVAGGP 1815
+ G++G GPP A GP
Sbjct: 1167 GNRGERGSEGSPGHPGQPGPPGPPGAPGP 1195
Score = 60.5 bits (145), Expect = 2e-08
Identities = 106/405 (26%), Positives = 131/405 (32%), Gaps = 58/405 (14%)
Query: 841 PGGLASLGKHRPKGFFATESSFDPHHRAQPSYERPSFLPPGP-GLMLRQKSIGAAEDDRP 899
PGG G KG P + P+ PPGP G+ + S G
Sbjct: 821 PGGKGERGAPGEKGEGGPPGVAGPPGGSGPAG------PPGPQGVKGERGSPGG------ 868
Query: 900 YLAPPAMKFSRSLSVPGSEDI-----PPPPTTSP----PEPPYSTPPVPSSSGRLTPSPR 950
P A F + +PG PP P+ SP P P P S G P+
Sbjct: 869 ---PGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPG--VSGPK 923
Query: 951 GGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPP 1010
G PG G A P GP G+R + P P P P
Sbjct: 924 GDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKP 983
Query: 1011 -PQPHHHHAHPPHPPEME----TGGSP--DDPPPRLALGPQPSLRGWRGG-GPSPTPGAP 1062
PP P + T G P D P L + G +G G + +PGAP
Sbjct: 984 GANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAP 1043
Query: 1063 -SPSHHGSAG-------GGGGSSQGPALRYFQLPPRAASAAMYVPARSG-RGRKGPLVKQ 1113
+P H G G G GPA P + A P G RG KG ++
Sbjct: 1044 GAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGA---PGPQGPRGDKGETGER 1100
Query: 1114 TKVEGEPQKG-GGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSS 1172
+ +G G P AP PA Q A+ +P + P S
Sbjct: 1101 GAAGIKGHRGFPGNPGAPGSPGPAGQQG--AIGSPGPAGP--------RGPVGPSGPPGK 1150
Query: 1173 QGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPSPVPTP 1217
G+S P P P G G GS SP P PP P P P
Sbjct: 1151 DGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGP 1195
Score = 50.1 bits (118), Expect = 2e-05
Identities = 36/100 (36%), Positives = 43/100 (43%), Gaps = 8/100 (8%)
Query: 453 APGAASS-GAPGPT-----SGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHP 506
APGA G PGP SG +G+S P+ P R A P+G R G
Sbjct: 1042 APGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERG 1101
Query: 507 EDAKRQPRGRPSSSGTP-REGPAGGTGGSGGPGGSLGSRG 545
+ RG P + G P GPAG G G PG + G RG
Sbjct: 1102 AAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPA-GPRG 1140
Score = 44.7 bits (104), Expect = 0.001
Identities = 35/100 (35%), Positives = 41/100 (41%), Gaps = 11/100 (11%)
Query: 453 APGAASSGAPGPTSGSQGQSQPSAPT-------TKLSSGTLRSASSPRGARARSPSRGRH 505
APG G P +G G S P+ P + S G +A P GAR G +
Sbjct: 829 APGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFP-GARGLPGPPGSN 887
Query: 506 PEDAKRQPRGRPSSSGTPREGPAGGTGGSGGPGGSLGSRG 545
P G P G P GPAG TG G PG S G +G
Sbjct: 888 GNPGPPGPSGSPGKDGPP--GPAGNTGAPGSPGVS-GPKG 924
Score = 42.4 bits (98), Expect = 0.005
Identities = 35/100 (35%), Positives = 42/100 (42%), Gaps = 11/100 (11%)
Query: 454 PGAASS-GAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQ 512
PGAA GAPG +G + P+ + R A P G R + GR
Sbjct: 479 PGAAGERGAPG----FRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPG 534
Query: 513 PRGRPSSSGTP----REGPAGGTGGSG--GPGGSLGSRGR 546
RG P S G P + GP G G SG GP G G RG+
Sbjct: 535 MRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQ 574
Score = 40.8 bits (94), Expect = 0.015
Identities = 32/98 (32%), Positives = 39/98 (39%), Gaps = 9/98 (9%)
Query: 452 SAPGAASSGAPGPTSGSQGQSQ---PSAPTTKLSSGTLRSASSPRGARARSPSRGRHPED 508
S G S G PGP GSQG+S P P+ + P+G G
Sbjct: 541 SPGGPGSDGKPGPP-GSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGP 599
Query: 509 AKRQPRGRPSSSG-TPREGPAGGTGGSGGPGGSLGSRG 545
P+G P +G T +GP G T GPGG G G
Sbjct: 600 GGPGPQGPPGKNGETGPQGPPGPT----GPGGDKGDTG 633
Score = 38.5 bits (88), Expect = 0.072
Identities = 46/163 (28%), Positives = 62/163 (38%), Gaps = 28/163 (17%)
Query: 454 PGAASSGAPGPTSGSQGQSQPSAPT-------TKLSSGTLRSASSP--RGARARSPSRGR 504
PGAA + GS GQ P P + + G + A SP GA + G
Sbjct: 314 PGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGP 373
Query: 505 HPEDAKRQPRGRPSSSGTP----REGPAG--------GTGGSGGPGGSLGSRGRRRKLYS 552
+ P G P +G+P GPAG G G GP G+ G+ G R +
Sbjct: 374 QGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGG--A 431
Query: 553 AVPGRSFMAVKSYQAQAEGEISL-----SKGEKIKVLSIGEGG 590
PG++ + GE + +KGE K S GE G
Sbjct: 432 GEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPG 474
Score = 38.1 bits (87), Expect = 0.094
Identities = 32/97 (32%), Positives = 40/97 (41%), Gaps = 5/97 (5%)
Query: 454 PGAAS-SGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQ 512
PG A GAPG G+ + AP K G A P G+ P G +R
Sbjct: 806 PGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPP-GPQGVKGERG 864
Query: 513 PRGRPSSSGTP-REGPAGGTGGSGGPG--GSLGSRGR 546
G P ++G P G G G +G PG G GS G+
Sbjct: 865 SPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGK 901
Score = 37.7 bits (86), Expect = 0.12
Identities = 38/142 (26%), Positives = 49/142 (34%), Gaps = 16/142 (11%)
Query: 413 SPKYAARRRGPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQS 472
+P R GP G G PP N +T P +G PGP G QG
Sbjct: 589 APGKNGERGGPGGPGPQGPPG---KNGETGPQGPPGPTGPGGDKGDTGPPGP-QGLQGLP 644
Query: 473 QPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTP-------RE 525
P + P+G + G + RG P +G P
Sbjct: 645 GTGGPPGENGKP---GEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPP 701
Query: 526 GPAGGTGGSG--GPGGSLGSRG 545
GP GG G +G GP G+ G+ G
Sbjct: 702 GPEGGKGAAGPPGPPGAAGTPG 723
Score = 37.7 bits (86), Expect = 0.12
Identities = 46/158 (29%), Positives = 56/158 (35%), Gaps = 31/158 (19%)
Query: 453 APGA-ASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPE---- 507
APG +G PGP G +G + P P + L+ RG +G E
Sbjct: 691 APGLRGGAGPPGP-EGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGP 749
Query: 508 --------DAKRQPRGR---PSSSGTP---REGPAGGTGGSGGPGGSLGSRGRRRKLYSA 553
D R P G P +G P EG A G G GP GS G RG +
Sbjct: 750 GADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGE-----TG 804
Query: 554 VPG-RSFMAVKSYQAQAEGEISLSKGEKIKVLSIGEGG 590
PG F + G KGE+ GEGG
Sbjct: 805 PPGPAGFPGAPGQNGEPGG-----KGERGAPGEKGEGG 837
Score = 37.4 bits (85), Expect = 0.16
Identities = 41/151 (27%), Positives = 56/151 (37%), Gaps = 23/151 (15%)
Query: 411 QESPKYAARRRGPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASS-GAPGPTSGSQ 469
+ P+ A +GPPG PP + + P + APG + G PGP +G+
Sbjct: 370 EPGPQGHAGAQGPPG-----PPGINGSPGGKGEMGPAGIP-GAPGLMGARGPPGP-AGAN 422
Query: 470 GQSQPSAPTTKLSSGTLRSASSPRGARARSPSRG---RHPEDAKRQPRGRPSSSGTPR-- 524
G + + PRG R + G ED K G P ++G P
Sbjct: 423 GAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAA 482
Query: 525 --------EGPAGGTG--GSGGPGGSLGSRG 545
GPAG G G GP G G+ G
Sbjct: 483 GERGAPGFRGPAGPNGIPGEKGPAGERGAPG 513
Score = 37.0 bits (84), Expect = 0.21
Identities = 28/93 (30%), Positives = 35/93 (37%), Gaps = 14/93 (15%)
Query: 460 GAPGPTS--GSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRP 517
G PGP G G++ P P G + + P G + G G P
Sbjct: 600 GGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPG---------TGGPP 650
Query: 518 SSSGTPRE-GPAGGTGGSGGPG--GSLGSRGRR 547
+G P E GP G G G PG G G+ G R
Sbjct: 651 GENGKPGEPGPKGDAGAPGAPGGKGDAGAPGER 683
Score = 37.0 bits (84), Expect = 0.21
Identities = 36/143 (25%), Positives = 50/143 (34%), Gaps = 18/143 (12%)
Query: 406 DVVPFQESPKYAARRRGPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPT 465
D VP ++ P+ GPPG PA + APG P +
Sbjct: 752 DGVPGKDGPRGPTGPIGPPG------PAGQPGDKGEG---------GAPGLPGIAGPRGS 796
Query: 466 SGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTP-R 524
G +G++ P P + +G R +G P G +G P
Sbjct: 797 PGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGP 856
Query: 525 EGPAGGTGGSGGPG--GSLGSRG 545
+G G G GGPG G G+RG
Sbjct: 857 QGVKGERGSPGGPGAAGFPGARG 879
Score = 36.6 bits (83), Expect = 0.27
Identities = 34/110 (30%), Positives = 42/110 (38%), Gaps = 24/110 (21%)
Query: 458 SSGAPGPT--SGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRG----RHPEDAK- 510
S+G PGP SGS G+ P P + S P+G + +G + P A
Sbjct: 886 SNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPG 945
Query: 511 -------------RQPRGRPSSSGTPREGPAGGTGGSGGPG--GSLGSRG 545
P G P G+P GP G G SG PG G G RG
Sbjct: 946 PLGIAGITGARGLAGPPGMPGPRGSP--GPQGVKGESGKPGANGLSGERG 993
Score = 35.8 bits (81), Expect = 0.47
Identities = 38/140 (27%), Positives = 47/140 (33%), Gaps = 17/140 (12%)
Query: 422 GPPGT----GLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQ------ 471
GPPGT G P + A P PGA P G G+
Sbjct: 183 GPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPP-GPPGAIGPSGPAGKDGESGRPGRPGE 241
Query: 472 -SQPSAPTTKLSSGT--LRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPRE-GP 527
P P K +G RG R+ +G + G P +G P GP
Sbjct: 242 RGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGP 301
Query: 528 AGGTGGSGGPG--GSLGSRG 545
G G G PG G+ G+RG
Sbjct: 302 RGAPGERGRPGLPGAAGARG 321
Score = 35.8 bits (81), Expect = 0.47
Identities = 33/96 (34%), Positives = 43/96 (44%), Gaps = 22/96 (22%)
Query: 459 SGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPS 518
+GAPGP G +G AP + G +A GAR +RG D + P G P
Sbjct: 293 NGAPGPM-GPRG-----APGERGRPGLPGAA----GARGNDGARG---SDGQPGPPGPPG 339
Query: 519 SSGTP-------REGPAGGTGGSGGPG--GSLGSRG 545
++G P GPAG G +G PG G G +G
Sbjct: 340 TAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQG 375
Score = 35.8 bits (81), Expect = 0.47
Identities = 42/139 (30%), Positives = 49/139 (35%), Gaps = 28/139 (20%)
Query: 421 RGPPG-TGLTVPPALLRANSDTSMALPDWMVFSAPGA-ASSGAPGPTSGSQGQSQ-PSAP 477
RGPPG G P L + PG + G PGP G +G++ P P
Sbjct: 413 RGPPGPAGANGAPGLRGGAGE-------------PGKNGAKGEPGPR-GERGEAGIPGVP 458
Query: 478 TTKLSSGTLRSASSP--RGARARSPSRGRHPEDAKRQPRGRPSSSGTPRE----GPAGGT 531
K G S P G + RG P G P G E GPAG
Sbjct: 459 GAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPR 518
Query: 532 GGSGGPG-----GSLGSRG 545
G +G PG G G RG
Sbjct: 519 GAAGEPGRDGVPGGPGMRG 537
Score = 35.8 bits (81), Expect = 0.47
Identities = 32/101 (31%), Positives = 38/101 (37%), Gaps = 10/101 (9%)
Query: 453 APG----AASSGAPGPT--SGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHP 506
APG A +G PG +G +G P+ P G R S G
Sbjct: 487 APGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPG 546
Query: 507 EDAKRQPRGRPSSSGTPREGPAGGTGGSGGPG--GSLGSRG 545
D K P G SG P GP G +G G PG G G +G
Sbjct: 547 SDGKPGPPGSQGESGRP--GPPGPSGPRGQPGVMGFPGPKG 585
Score = 35.8 bits (81), Expect = 0.47
Identities = 27/94 (28%), Positives = 37/94 (39%), Gaps = 4/94 (4%)
Query: 455 GAASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPR 514
G+ +G PGP + P P G R P G+ G K P
Sbjct: 847 GSGPAGPPGPQGVKGERGSPGGPGAAGFPGA-RGLPGPPGSNGNPGPPGPSGSPGKDGPP 905
Query: 515 GRPSSSGTP-REGPAGGTGGSGGPG--GSLGSRG 545
G ++G P G +G G +G PG GS G++G
Sbjct: 906 GPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQG 939
Score = 35.8 bits (81), Expect = 0.47
Identities = 29/95 (30%), Positives = 35/95 (36%), Gaps = 3/95 (3%)
Query: 454 PG-AASSGAPGPTSGSQGQSQPSAPTTKLSSGTLR--SASSPRGARARSPSRGRHPEDAK 510
PG A ++GAPG S + P K S G A P G + +RG
Sbjct: 905 PGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGM 964
Query: 511 RQPRGRPSSSGTPREGPAGGTGGSGGPGGSLGSRG 545
PRG P G E G G G G G +G
Sbjct: 965 PGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQG 999
Score = 35.0 bits (79), Expect = 0.80
Identities = 29/96 (30%), Positives = 38/96 (39%), Gaps = 8/96 (8%)
Query: 460 GAPGPTSGSQGQSQPSAPTTKLSSGTL-----RSASSPRGARARSPSRGRHPEDAKRQPR 514
G PGP + + AP +G R + P G + G++ E + R
Sbjct: 768 GPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGER 827
Query: 515 GRPSSSGTPRE-GPAGGTGGSG--GPGGSLGSRGRR 547
G P G G AG GGSG GP G G +G R
Sbjct: 828 GAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGER 863
Score = 34.3 bits (77), Expect = 1.4
Identities = 36/112 (32%), Positives = 42/112 (37%), Gaps = 11/112 (9%)
Query: 454 PGAASS-GAPGPTSGSQGQSQPSAPTTKLSSGTLRSA--SSPRGARARSPSRGRHPEDAK 510
PG A G PGP S P +P + G A S P G G +D +
Sbjct: 173 PGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGE 232
Query: 511 RQPRGRPSSSGTPREGPAGGTGGSGGPG-----GSLGSRGRR-RKLYSAVPG 556
GRP G P GP G G +G PG G G GR K + PG
Sbjct: 233 SGRPGRPGERGLP--GPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPG 282
Score = 34.3 bits (77), Expect = 1.4
Identities = 43/162 (26%), Positives = 55/162 (33%), Gaps = 15/162 (9%)
Query: 453 APGAASS----GAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPED 508
+PG A G+PGP +G +G PS P K + P G R RG
Sbjct: 1120 SPGPAGQQGAIGSPGP-AGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSP 1178
Query: 509 AKRQPRGRPSSSGTPREGP-AGGTG-----GSGG--PGGSLGSRGRRRKLYSAVPGRSFM 560
G P G P GP GG G G GG GG G +
Sbjct: 1179 GHPGQPGPPGPPGAP--GPCCGGVGAAAIAGIGGEKAGGFAPYYGDEPMDFKINTDEIMT 1236
Query: 561 AVKSYQAQAEGEISLSKGEKIKVLSIGEGGFWEGQVKGRVGW 602
++KS Q E IS K + + F ++K W
Sbjct: 1237 SLKSVNGQIESLISPDGSRKNPARNCRDLKFCHPELKSGEYW 1278
Score = 32.7 bits (73), Expect = 4.0
Identities = 51/189 (26%), Positives = 65/189 (34%), Gaps = 48/189 (25%)
Query: 409 PFQESPKYAARRRGPPG----TGLTVPPALLRANSDTSMALPDWMVFSAPGAASS-GAPG 463
P P + + GPPG TG P + D +PGA GAPG
Sbjct: 890 PGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEK----GSPGAQGPPGAPG 945
Query: 464 PT-----SGSQGQS-QPSAPTTKLSSGT--LRSASSPRGARARSPSRGRHPEDAKRQPR- 514
P +G++G + P P + S G ++ S GA S RG P + P
Sbjct: 946 PLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERG--PPGPQGLPGL 1003
Query: 515 ----------GRPSSSGTP-REGPAGGTGGSG-----------------GPGGSLGSRGR 546
G P S G P R+G GG G G GP G G G
Sbjct: 1004 AGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGD 1063
Query: 547 RRKLYSAVP 555
R + A P
Sbjct: 1064 RGESGPAGP 1072
Score = 32.3 bits (72), Expect = 5.2
Identities = 55/211 (26%), Positives = 74/211 (35%), Gaps = 50/211 (23%)
Query: 371 ADKDVKNNNGQTPFQVAVI-AGNFELGELIRNHREQDV----VPFQE----------SPK 415
AD+DV P Q+ V +G+ ++I + +E D +PF E +P
Sbjct: 40 ADRDVWKPE---PCQICVCDSGSVLCDDIICDDQELDCPNPEIPFGECCAVCPQPPTAPT 96
Query: 416 YAARRRGPPGT-GLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPT-------SG 467
+GP G G PP + N D + PG S G+PGP +G
Sbjct: 97 RPPNGQGPQGPKGDPGPPGIPGRNGDPGIP-------GQPG--SPGSPGPPGICESCPTG 147
Query: 468 SQGQSQPSAPTTKLSSGTL----------RSASSPRGARARSPSRGRHPEDAKRQPRGRP 517
Q S P + + SG P G S G + P G P
Sbjct: 148 PQNYS-PQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEP 206
Query: 518 SSSGTPREGPAGGTG--GSGGPGGSLGSRGR 546
+G GP G G G GP G G GR
Sbjct: 207 GQAGP--SGPPGPPGAIGPSGPAGKDGESGR 235
Score = 32.0 bits (71), Expect = 6.8
Identities = 37/142 (26%), Positives = 46/142 (32%), Gaps = 13/142 (9%)
Query: 413 SPKYAARRRGPPG----TGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGS 468
SP Y +GPPG G + PP A + A D G PGP
Sbjct: 196 SPGY----QGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIK 251
Query: 469 QGQSQPSAPTTKLSSGT-----LRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTP 523
P P K G + + G + + G + PRG P G P
Sbjct: 252 GPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRP 311
Query: 524 REGPAGGTGGSGGPGGSLGSRG 545
A G G+ G GS G G
Sbjct: 312 GLPGAAGARGNDGARGSDGQPG 333
Score = 32.0 bits (71), Expect = 6.8
Identities = 25/95 (26%), Positives = 32/95 (33%), Gaps = 4/95 (4%)
Query: 454 PGAASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQP 513
PGA + G G + + + R + P G G P
Sbjct: 458 PGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGP 517
Query: 514 RGRPSSSGTPREGPAGGTGGSGGPG--GSLGSRGR 546
RG G R+G GG G G PG G GS G+
Sbjct: 518 RGAAGEPG--RDGVPGGPGMRGMPGSPGGPGSDGK 550
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 121 bits (303), Expect = 8e-27
Identities = 305/1240 (24%), Positives = 378/1240 (30%), Gaps = 246/1240 (19%)
Query: 914 VPGSEDIPPPPTTSPPEPPYSTPP---------------VPSSSGRLTPSPRGGPFNPGS 958
+PG +P PP PP PP PP S+ G P P G G
Sbjct: 134 IPGQPGLPGPP--GPPGPP--GPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGL 189
Query: 959 GGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHA 1018
GP A P F GP G+ SGP+ P PP P
Sbjct: 190 PGPPGAPGPQGFQGPPGEPGEPGA-------SGPMGP------------RGPPGP----- 225
Query: 1019 HPPHPPEMETGGSPDDPPPRLALGPQ-----------PSLRGWRG-GGPSPTPGAPSPSH 1066
P + G P P R GPQ P ++G RG G G P+
Sbjct: 226 -PGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAG 284
Query: 1067 HGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGR-GRKGPLVKQTKVEGEPQKGGG 1125
G G + P Q+ PR +P GR G GP G G
Sbjct: 285 PKGEPGSPGENGAPG----QMGPRG------LPGERGRPGAPGP----AGARGNDGATGA 330
Query: 1126 LPPAPSPTSPASPQP-PPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQ 1184
P P PT PA P P AV A E P + P G + A P
Sbjct: 331 AGP-PGPTGPAGPPGFPGAVGAKGEAG--PQGPRGSEGPQGVRGEPGPPGPAGAAGPAGN 387
Query: 1185 PEPTGGGGGGGSSPSPAPAMSPVPPSPSPVPTPASPSGPATLDFTSQFGAALVGAARREG 1244
P G G G++ +P A +P P P P GP S G ++ +
Sbjct: 388 PGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNS--GEPGAPGSKGDT 445
Query: 1245 GWQNEARRRSTLFLSTDAGDED--GGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLE 1302
G + E AG+E G G G PGP G A+ +
Sbjct: 446 GAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPK 505
Query: 1303 SAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARER 1362
G G AG + G G P LTG P SP +
Sbjct: 506 GPAGERGSPG-PAGPKGSPGEAGRPGEAGL----PGAKGLTG---SPGSP-----GPDGK 552
Query: 1363 ALKESSEGGGAPQPPPRPPSPRYEA-----PPPTPHHHSPHAHHEPVLRLWGASPPDPAR 1417
G PP PP R +A P P P E G P A
Sbjct: 553 TGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGER-----GVPGPPGAV 607
Query: 1418 RELGYRAGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPG-VSKP 1476
G G+Q PA P R + P +PG G PA PG KP
Sbjct: 608 GPAGKDGEAGAQGPPGPAGPAGERG---EQGPAGSPGF------QGLPGPAGPPGEAGKP 658
Query: 1477 WRSAAPEEPERLPLHVRFLENCQPRAPVTSG----RGPPSEDG-PGVPPPSPRRSVPPSP 1531
P + AP SG RG P E G G P P+ R +P
Sbjct: 659 GEQGVPGD---------------LGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAP 703
Query: 1532 TSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHP 1591
+ A + G P AP + GE LP P + P
Sbjct: 704 GNDGAKGDAGAPGAPGSQGAPGLQGMPGE-RGAAGLPGP-------KGDRGDAGPKGADG 755
Query: 1592 LPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPP 1651
P P+ PP A AP + S + + GA APGD PGPP
Sbjct: 756 SPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPT-------GARGAPGDRGEPGPP 808
Query: 1652 AP---AAPAPAAPQPGPDPPPGT-----DSGIEEVDSRSSSDHPLETISSASTLSSLSAE 1703
P A P A QPG PG D+G + P+ + + + +
Sbjct: 809 GPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSA 868
Query: 1704 G-GGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRAL 1762
G G+ G G AG GP G + PGPP P RG
Sbjct: 869 GPPGATGFPGAAGRVGPPGPS--------------GNAGPPGPPGPAGKEGGKGPRGET- 913
Query: 1763 GASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAG--GPVAV-- 1818
G +G RPG G P P P G DG GP G+AG G V +
Sbjct: 914 GPAG--RPGEVG----PPGPPGPAGEKGSPGADGPAGAPGTPGP--QGIAGQRGVVGLPG 965
Query: 1819 ---EPEVPPVPLPTASSLPRKLLPWEEGP-------GPPPPPLPGPLAQPQASALATVKA 1868
E P +P P+ P ++GP GPP P P LA P
Sbjct: 966 QRGERGFPGLPGPSGE-------PGKQGPSGASGERGPPGPMGPPGLAGPPGE------- 1011
Query: 1869 SIISELSSKLQQFGGSSAAG-GALPWARGGSGGGGDSHHGGASYVPERTSSLQRQRLSDD 1927
S + G + G P A+G G G + GA P + S D
Sbjct: 1012 ------SGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGD 1065
Query: 1928 SQSSLLSKPVSSLFQNWPKPPLPPLPTGTGVSPTAAAAP-GATSPSASSSSTSTRHLQGV 1986
+ P P P V P A P G P T + +G+
Sbjct: 1066 RG------------ETGPAGPAGP------VGPVGARGPAGPQGPRGDKGETGEQGDRGI 1107
Query: 1987 EFEMRPPLLRRAPSPSLLPASEHKVSPAPRPSSLPILPSGPL----YPGLFDIRGSP--- 2039
+ L+ P P P + P +S P P GP PG + G P
Sbjct: 1108 KGHRGFSGLQGPPGPPGSPGEQ-----GPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPI 1162
Query: 2040 -TGGAGGSADPFAPVFVPPHPGISGGLGGALSGASRSLSP 2078
G G PV P PG G G +G S P
Sbjct: 1163 GPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLP 1202
Score = 103 bits (258), Expect = 1e-21
Identities = 243/1012 (24%), Positives = 300/1012 (29%), Gaps = 176/1012 (17%)
Query: 839 PGPGGLASLGKHRPKGFFATESSFDPHHRAQPSYERPSFLPPG----PGLMLRQKSIGAA 894
PG GL + HR GF + + A P E S PG PG M + G
Sbjct: 256 PGTAGLPGMKGHR--GFSGLDGAKGDAGPAGPKGEPGS---PGENGAPGQMGPRGLPG-- 308
Query: 895 EDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPVPSSSGRLTPS------ 948
E RP PA G+ PP + P P P + G P
Sbjct: 309 ERGRPGAPGPAGARGND----GATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSE 364
Query: 949 -PRGGPFNPGSGGPLPASSPASFDGPS-PPDTRVGSREKSLYHSGPLPPAHHHPPHHHHH 1006
P+G PG GP A+ PA G P + + + + P A P
Sbjct: 365 GPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARG--PSGPQG 422
Query: 1007 HAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGP-----QPSLRGWRGG-GPSPTPG 1060
PP P + P P G+ +P P GP + RG RG GP+ PG
Sbjct: 423 PGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPG 482
Query: 1061 APS----PSHHGSAGGGG-GSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTK 1115
P P G G G +GPA P + P +GR + L
Sbjct: 483 PPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGS---PGEAGRPGEAGLPGAKG 539
Query: 1116 VEGEPQKGG--GLPPAPSPTSP-ASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSS 1172
+ G P G G P P P PP A + + P P ++
Sbjct: 540 LTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFP-----GPKGAAGEPGK 594
Query: 1173 QGSSTEAEPPTQPEPTGGGGGGGSSPSPAPA-----MSPVPPSPSP----VPTPASPSG- 1222
G PP P G G G+ P PA P+ SP +P PA P G
Sbjct: 595 AGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGE 654
Query: 1223 ---PATLDFTSQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDED--GGDGGLGTGAA 1277
P GA AR E G+ E + + G G DG G A
Sbjct: 655 AGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGA 714
Query: 1278 PGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRP 1337
PG +GM L G G + G G PP P
Sbjct: 715 PGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGP 774
Query: 1338 LVHPLTGKALDPASPLGLALAARERALKESSEGGGAPQPPPRPPSPRYEAPPPTPHHHSP 1397
P P+ P G + G + P PP P A PP P
Sbjct: 775 AGAPGDKGESGPSGPAG----------PTGARGAPGDRGEPGPPGPAGFAGPPGADGQ-P 823
Query: 1398 HAHHEP--VLRLWGASPPDPARRE-----LGYRAGLGSQEKSLPASPPAARRSLLHRLPP 1450
A EP A PP PA +G G++ A PP A P
Sbjct: 824 GAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATG-----FPG 878
Query: 1451 TAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEE---PERLPLHVRFLENCQPRAPVTSG 1507
A VGP PP P PG + P P P V P P +G
Sbjct: 879 AAGRVGPPGPSGNAGPPGP-PGPAGKEGGKGPRGETGPAGRPGEVG-----PPGPPGPAG 932
Query: 1508 -RGPPSEDGPGVPPPSP-------------------RRSVP--PSPTSPR-------ASE 1538
+G P DGP P +P R P P P+ AS
Sbjct: 933 EKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASG 992
Query: 1539 ENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEK-----------PESPLTPG 1587
E G P + PP E G P + K P +P PG
Sbjct: 993 ERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPG 1052
Query: 1588 PPHPLPDT--------PAPATPLPPVPPPAVA--AAPPTLDSTASSLTSYDSEVATLTQG 1637
P P+ PA P PV P A P +G
Sbjct: 1053 APGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRG 1112
Query: 1638 ASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTL 1697
S G P PPG P P+ A+ GP PPG+ +G D + P+
Sbjct: 1113 FSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGS-AGAPGKDGLNGLPGPI--------- 1162
Query: 1698 SSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPP 1749
G G G G GP G PGPP PP
Sbjct: 1163 --------GPPGPRGRTGDAGPVGPP--------------GPPGPPGPPGPP 1192
Score = 97.8 bits (242), Expect = 1e-19
Identities = 220/904 (24%), Positives = 283/904 (31%), Gaps = 175/904 (19%)
Query: 835 ASESPGPGGL----ASLGKHRPKGFFATESSFDPHHRAQPSYERPSFLPPGPGLMLRQKS 890
A PGP GL G +GF + P P+ ER S P GP + S
Sbjct: 471 ARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKG---PAGERGSPGPAGP-----KGS 522
Query: 891 IGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPVPSSSGRLT---- 946
G A P A + S PG + PP + + P P + G+
Sbjct: 523 PGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGF 582
Query: 947 PSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHH 1006
P P+G PG G P GP+ D G++ PP P
Sbjct: 583 PGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQG---------PPGPAGPAGERGE 633
Query: 1007 HAPPPQPHHHHAHPPHPPEMETG-----GSPDD---PPPRLALGPQ--PSLRGWRG---- 1052
P P P P E G G P D P P A G + P RG +G
Sbjct: 634 QGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGP 693
Query: 1053 GGPSPTPGAP-SPSHHGSAGGGG--GSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGP 1109
GP GAP + G AG G GS P L+ +P +A + P + RG GP
Sbjct: 694 AGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQ--GMPGERGAAGLPGP-KGDRGDAGP 750
Query: 1110 LVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSG 1169
+G P K G T P P P PA A + S P P+ +
Sbjct: 751 ----KGADGSPGKDG----VRGLTGPIGP-PGPAGAPGDKGESGP------SGPAGPTGA 795
Query: 1170 RSSQGSSTEAEPPTQPE---PTGGGGGGGSSPSPAPAMSPVPPSPSPVPTPASPSGPATL 1226
R + G E PP P G G G+ P A + P PA P GP
Sbjct: 796 RGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPI-- 853
Query: 1227 DFTSQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSK 1286
VGA +G + +T F A G G G PGP K
Sbjct: 854 --------GNVGAPGAKGARGSAGPPGATGF--PGAAGRVGPPGPSGNAGPPGPPGPAGK 903
Query: 1287 SIDEGMFSAEPYLRLESAGSGAGYGGYG----AGSRAYGGGGGSSAFTSFLPPRPL---- 1338
+G P AG G G AG + G G + P+ +
Sbjct: 904 EGGKG-----PRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQR 958
Query: 1339 -VHPLTGKALDPASPLGLALAARERALKESSEGGGAPQPPPRPPSPRYEAPPPTPHHHSP 1397
V L G+ + P GL + E K+ G + PP P P A PP
Sbjct: 959 GVVGLPGQRGERGFP-GLPGPSGEPG-KQGPSGASGERGPPGPMGPPGLAGPPGESGRE- 1015
Query: 1398 HAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAARRSLLHRLPPTAPG-VG 1456
GA + + G G + ++ PA PP A + P APG VG
Sbjct: 1016 -----------GAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGA------PGAPGPVG 1058
Query: 1457 PLLLQ--LGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPPSED 1514
P G PA G P + P P+ P + Q + RG
Sbjct: 1059 PAGKSGDRGETGPAGPAGPVGPVGARGPAGPQG-PRGDKGETGEQGDRGIKGHRGFSGLQ 1117
Query: 1515 GPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFS 1574
GP PP SP P + P PP + +DG + LP P+
Sbjct: 1118 GPPGPPGSPGEQGPSGASGPAGPRG--------PPGSAGAPGKDG----LNGLPGPI--- 1162
Query: 1575 NSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATL 1634
GPP P T PP PP
Sbjct: 1163 ------------GPPGPRGRTGDAGPVGPPGPP--------------------------- 1183
Query: 1635 TQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSA 1694
G P PPGPP+ PQP + D+ D LE ++
Sbjct: 1184 --------GPPGPPGPPSAGFDFSFLPQPPQEKAHDGGRYYRADDANVVRDRDLEVDTTL 1235
Query: 1695 STLS 1698
+LS
Sbjct: 1236 KSLS 1239
Score = 85.1 bits (209), Expect = 7e-16
Identities = 242/999 (24%), Positives = 306/999 (30%), Gaps = 261/999 (26%)
Query: 1104 RGRKGPLVKQTKVEGEPQKGG--GLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIK 1161
RG +GP G P + G G P P P P P PP + P +
Sbjct: 120 RGPRGPA-------GPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFA------PQLSYG 166
Query: 1162 APSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPSPVPTPASPS 1221
S+ G S G + P P P G G G P P P S P P
Sbjct: 167 YDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPG---EPGEPGASGPMGPRGPP 223
Query: 1222 GPATLDFTSQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPR 1281
GP + G EA + G + G G GT PG
Sbjct: 224 GPPG-----------------KNGDDGEAGKPGRPGERGPPGPQ-GARGLPGTAGLPG-- 263
Query: 1282 LRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHP 1341
M + L+ A AG AG + G G + + PR L
Sbjct: 264 ----------MKGHRGFSGLDGAKGDAG----PAGPKGEPGSPGENGAPGQMGPRGL--- 306
Query: 1342 LTGKALDPASPLGLALAARERALKESSEGGGAPQPPPRPPSPRYEAPPPTPHHHSPHAHH 1401
G+ P +P G A A ++G PP P P
Sbjct: 307 -PGERGRPGAP-GPAGA-------RGNDGATGAAGPPGPTGP------------------ 339
Query: 1402 EPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQ 1461
A PP G+ +G++ ++ P P + R P PG
Sbjct: 340 --------AGPP-------GFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPA----- 379
Query: 1462 LGTEPPAPHPGVS-KPWRSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPP 1520
G PA +PG +P A P P P RGP GPG PP
Sbjct: 380 -GAAGPAGNPGADGQPGAKGANGAPGIAGA---------PGFP--GARGPSGPQGPGGPP 427
Query: 1521 -PSPRRSVPPSPTSPRASEENGLP--LLVLPPPAPSVDVEDGEFLFVEPLP-----PPLE 1572
P P +P S + G P + V PP P+ + E EP P PP E
Sbjct: 428 GPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGE-EGKRGARGEPGPTGLPGPPGE 486
Query: 1573 FSNSFEK--PESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLTSYDSE 1630
+ P + GP P + +P P P P A P +
Sbjct: 487 RGGPGSRGFPGADGVAGPKGPAGERGSPG-PAGPKGSPGEAGRPGEAGLPGA-------- 537
Query: 1631 VATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHPLET 1690
+G + +PG P P G P PA +PGP PPG
Sbjct: 538 -----KGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPG-------------------- 572
Query: 1691 ISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQ 1750
G AG G G A+G G + G P PP
Sbjct: 573 -------------ARGQAGVMGFPGPKGAAGEP--------------GKAGERGVPGPPG 605
Query: 1751 LMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAG 1810
+ P+ G A GA G PGP+G P AG+ G L +GPP G
Sbjct: 606 AVGPAGKDGEA-GAQG--PPGPAG-------PAGERGEQGPAGSPGFQGLPGPAGPP--G 653
Query: 1811 VAGGPVAVEPEVP---PVPLPTASSLPRKLLPWEEG-PGPPPPPLP----GPLAQPQASA 1862
AG P E VP P P+ + R P E G GPP P P G A
Sbjct: 654 EAGKP--GEQGVPGDLGAPGPSGARGERG-FPGERGVQGPPGPAGPRGANGAPGNDGAKG 710
Query: 1863 LATVKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQRQ 1922
A + S+ + LQ G A G LP +G G G G+
Sbjct: 711 DAGAPGAPGSQGAPGLQGMPGERGAAG-LPGPKGDRGDAGPKGADGS------------- 756
Query: 1923 RLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGVSPTAAAAPGATSPSASSSSTSTRH 1982
P + P PP P G A G + PS + T R
Sbjct: 757 -------------PGKDGVRGLTGPIGPPGPAG------APGDKGESGPSGPAGPTGARG 797
Query: 1983 LQGVEFEMRPP---LLRRAPSPSLLPASEHKVSPA--------PRPSSLPILPSGPL--- 2028
G E PP P P ++ + A P P+ P P GP+
Sbjct: 798 APGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAG-PAGPPGPIGNV 856
Query: 2029 -YPGLFDIRGSPTGGAGGSADPFAPVFVPPHPGISGGLG 2066
PG RGS G G + P A V P PG SG G
Sbjct: 857 GAPGAKGARGS-AGPPGATGFPGAAGRVGP-PGPSGNAG 893
Score = 52.0 bits (123), Expect = 6e-06
Identities = 51/177 (28%), Positives = 70/177 (39%), Gaps = 45/177 (25%)
Query: 409 PFQESPKYAARRRGPPGT----GLTVPPA---------------------LLRANSDTSM 443
P ++ P A+ RGPPG GL PP +T
Sbjct: 982 PGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGP 1041
Query: 444 ALPDWMVFSAPGAASSGAPGPT-----SGSQGQSQPSAPTTKLSSGTLRSASSPRGARAR 498
A P APGA GAPGP SG +G++ P+ P + R + P+G R
Sbjct: 1042 AGPP----GAPGAP--GAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGD 1095
Query: 499 SPSRGRHPEDAKRQPR------GRPSSSGTPRE-GPAGGTGGSG--GPGGSLGSRGR 546
G + + R G P G+P E GP+G +G +G GP GS G+ G+
Sbjct: 1096 KGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGK 1152
Score = 47.8 bits (112), Expect = 1e-04
Identities = 39/129 (30%), Positives = 49/129 (37%), Gaps = 15/129 (11%)
Query: 422 GPPGTGLTVPPALLRANSDTS---MALPDWMVFSAPGAASS--GAPGPTSGSQGQSQPSA 476
GPPG G P L + S +++P M S P GAPGP +P
Sbjct: 151 GPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGE 210
Query: 477 PTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPREGPAGGTGGSGG 536
P AS P G R G++ +D + GRP G P A G G+ G
Sbjct: 211 P----------GASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAG 260
Query: 537 PGGSLGSRG 545
G G RG
Sbjct: 261 LPGMKGHRG 269
Score = 44.7 bits (104), Expect = 0.001
Identities = 42/128 (32%), Positives = 52/128 (40%), Gaps = 20/128 (15%)
Query: 454 PGAASS-GAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQ 512
PGAA G PGP SG+ G P P K +G R + GR E
Sbjct: 877 PGAAGRVGPPGP-SGNAGPPGPPGPAGK---------EGGKGPRGETGPAGRPGEVGPPG 926
Query: 513 PRGRPSSSGTP-REGPAGGTGGSGGPGGSLGSRG-------RRRKLYSAVPGRSFMAVKS 564
P G G+P +GPAG G+ GP G G RG R + + +PG S K
Sbjct: 927 PPGPAGEKGSPGADGPAGAP-GTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQ 985
Query: 565 YQAQAEGE 572
+ A GE
Sbjct: 986 GPSGASGE 993
Score = 43.9 bits (102), Expect = 0.002
Identities = 48/156 (30%), Positives = 54/156 (34%), Gaps = 29/156 (18%)
Query: 412 ESPKYAARRRGPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASS----GAPGPTSG 467
E P+ GPPG PA N APG A + GA GP SG
Sbjct: 364 EGPQGVRGEPGPPGPAGAAGPA---GNPGADGQPGAKGANGAPGIAGAPGFPGARGP-SG 419
Query: 468 SQGQSQPSAPTTKL-------SSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSS 520
QG P P S G + P + P G E+ KR RG P +
Sbjct: 420 PQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPP-GPAGEEGKRGARGEPGPT 478
Query: 521 GTPREGPAGGTGGSG-----------GPGGSLGSRG 545
G P GP G GG G GP G G RG
Sbjct: 479 GLP--GPPGERGGPGSRGFPGADGVAGPKGPAGERG 512
Score = 42.7 bits (99), Expect = 0.004
Identities = 44/159 (27%), Positives = 56/159 (35%), Gaps = 18/159 (11%)
Query: 421 RGPPG-TGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQSQPSAPTT 479
RG PG TGL PP PGA P +G +G P+ P
Sbjct: 472 RGEPGPTGLPGPPGERGGPGSRGF----------PGADGVAGPKGPAGERGSPGPAGPKG 521
Query: 480 KLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTP-REGPAGGTGGSG--- 535
+ GA+ + S G D K P G G P GP G G +G
Sbjct: 522 SPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMG 581
Query: 536 --GPGGSLGSRGRR-RKLYSAVPGRSFMAVKSYQAQAEG 571
GP G+ G G+ + PG A K +A A+G
Sbjct: 582 FPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQG 620
Score = 42.4 bits (98), Expect = 0.005
Identities = 42/151 (27%), Positives = 53/151 (35%), Gaps = 31/151 (20%)
Query: 409 PFQESPKYAARRRGPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTS-- 466
P Q P+ RG PG PA R N A GAA G PGPT
Sbjct: 298 PGQMGPRGLPGERGRPGAP---GPAGARGND------------GATGAA--GPPGPTGPA 340
Query: 467 ---------GSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAK---RQPR 514
G++G++ P P +R P G + G D + +
Sbjct: 341 GPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGAN 400
Query: 515 GRPSSSGTPREGPAGGTGGSGGPGGSLGSRG 545
G P +G P A G G GPGG G +G
Sbjct: 401 GAPGIAGAPGFPGARGPSGPQGPGGPPGPKG 431
Score = 41.2 bits (95), Expect = 0.011
Identities = 45/145 (31%), Positives = 52/145 (35%), Gaps = 23/145 (15%)
Query: 422 GPPG-TGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQSQPSA---- 476
GPPG TG PP A A P S G PGP G G + P+
Sbjct: 332 GPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPP-GPAGAAGPAGNPGA 390
Query: 477 ---PTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPREGPAGGTGG 533
P K ++G A +P AR PS + P P+G G P G G TG
Sbjct: 391 DGQPGAKGANGAPGIAGAPGFPGARGPSGPQGP-GGPPGPKGNSGEPGAP--GSKGDTGA 447
Query: 534 SG-----------GPGGSLGSRGRR 547
G GP G G RG R
Sbjct: 448 KGEPGPVGVQGPPGPAGEEGKRGAR 472
Score = 41.2 bits (95), Expect = 0.011
Identities = 37/107 (34%), Positives = 48/107 (44%), Gaps = 13/107 (12%)
Query: 454 PGAASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQP 513
PG A GAPG G G S P+ PT + R P G P+ P A QP
Sbjct: 772 PGPA--GAPGD-KGESGPSGPAGPTGARGAPGDRGEPGPPG-----PAGFAGPPGADGQP 823
Query: 514 --RGRPSSSGTPRE-GPAGGTGGSGGPG--GSLGSRGRRRKLYSAVP 555
+G P +G + GP G G +G PG G++G+ G + SA P
Sbjct: 824 GAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGP 870
Score = 38.1 bits (87), Expect = 0.094
Identities = 34/109 (31%), Positives = 44/109 (40%), Gaps = 19/109 (17%)
Query: 454 PGAA----SSGAPGPTSGSQGQSQPSAPTTKLSSGTL-----RSASS---PRGARARSPS 501
PG A ++GAPG P AP ++ + G R A+ P+G R +
Sbjct: 691 PGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGP 750
Query: 502 RGRHPEDAKRQPRGRPSSSGTPREGPAGGTGGSG-----GPGGSLGSRG 545
+G K RG G P GPAG G G GP G G+RG
Sbjct: 751 KGADGSPGKDGVRGLTGPIGPP--GPAGAPGDKGESGPSGPAGPTGARG 797
Score = 37.0 bits (84), Expect = 0.21
Identities = 39/131 (29%), Positives = 47/131 (35%), Gaps = 23/131 (17%)
Query: 422 GPPGT-GLTVPPALLRANSDTSMALPDWMVFSAPGAAS-SGAPGPTS--GSQGQSQPSAP 477
GPPG G + P + DT PG G PGP G +G P
Sbjct: 425 GPPGPKGNSGEPGAPGSKGDTGAK-------GEPGPVGVQGPPGPAGEEGKRGARGEPGP 477
Query: 478 TTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTP-REGPAGGTGGSGG 536
T P G R SRG D P+G G+P GP G G +G
Sbjct: 478 T---------GLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGR 528
Query: 537 PG--GSLGSRG 545
PG G G++G
Sbjct: 529 PGEAGLPGAKG 539
Score = 37.0 bits (84), Expect = 0.21
Identities = 38/135 (28%), Positives = 49/135 (36%), Gaps = 12/135 (8%)
Query: 414 PKYAARRRGPPGT-GLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTS--GSQG 470
PK AA G G G+ PP + A A A G GP G QG
Sbjct: 585 PKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQG 644
Query: 471 QSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPREGPAGG 530
P+ P + + GA S +RG +R +G P GPAG
Sbjct: 645 LPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPP--------GPAGP 696
Query: 531 TGGSGGPGGSLGSRG 545
G +G PG G++G
Sbjct: 697 RGANGAPGND-GAKG 710
Score = 37.0 bits (84), Expect = 0.21
Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 7/94 (7%)
Query: 458 SSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRP 517
++G PGP G +G + P +R + P G + + G E P G
Sbjct: 735 AAGLPGP-KGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPT 793
Query: 518 SSSGTPRE----GPAGGTGGSGGPG--GSLGSRG 545
+ G P + GP G G +G PG G G++G
Sbjct: 794 GARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKG 827
Score = 36.6 bits (83), Expect = 0.27
Identities = 31/103 (30%), Positives = 38/103 (36%), Gaps = 4/103 (3%)
Query: 456 AASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRG 515
A + G PGP G GQ + P G + G E P G
Sbjct: 943 AGAPGTPGP-QGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMG 1001
Query: 516 RPSSSGTPRE-GPAGGTGGSGGPG--GSLGSRGRRRKLYSAVP 555
P +G P E G G G G PG GS G++G R + A P
Sbjct: 1002 PPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGP 1044
Score = 36.2 bits (82), Expect = 0.36
Identities = 32/105 (30%), Positives = 41/105 (39%), Gaps = 18/105 (17%)
Query: 454 PGAASS--GAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKR 511
P AS G PGP G G + P + + A G+ R S G + +
Sbjct: 987 PSGASGERGPPGPM-GPPGLAGPPGESGR------EGAPGAEGSPGRDGSPGAKGDRGET 1039
Query: 512 QPRGRPSSSGTPRE----GPAGGTG-----GSGGPGGSLGSRGRR 547
P G P + G P GPAG +G G GP G +G G R
Sbjct: 1040 GPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGAR 1084
Score = 35.8 bits (81), Expect = 0.47
Identities = 30/96 (31%), Positives = 38/96 (39%), Gaps = 8/96 (8%)
Query: 453 APGA-ASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKR 511
APGA S GAPG + P K G + P+GA S G+
Sbjct: 714 APGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGD----AGPKGADG---SPGKDGVRGLT 766
Query: 512 QPRGRPSSSGTPREGPAGGTGGSGGPGGSLGSRGRR 547
P G P +G P + G G GP G+ G+ G R
Sbjct: 767 GPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDR 802
Score = 35.4 bits (80), Expect = 0.61
Identities = 39/137 (28%), Positives = 48/137 (35%), Gaps = 18/137 (13%)
Query: 420 RRGPPGT----GLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQSQPS 475
+ GPPG G PP A + M F P A+ G PG +G +G P
Sbjct: 552 KTGPPGPAGQDGRPGPPGPPGARGQAGV-----MGFPGPKGAA-GEPGK-AGERGVPGPP 604
Query: 476 APTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPREGPAGGTGGSG 535
A P G + RG +G P +G P G AG G G
Sbjct: 605 GAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPP--GEAGKPGEQG 662
Query: 536 GPG-----GSLGSRGRR 547
PG G G+RG R
Sbjct: 663 VPGDLGAPGPSGARGER 679
Score = 35.4 bits (80), Expect = 0.61
Identities = 30/99 (30%), Positives = 40/99 (40%), Gaps = 9/99 (9%)
Query: 454 PGAASSGAPGPT-----SGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPED 508
PGA G PG +G G + P+ P + + A RG+ + G
Sbjct: 823 PGA--KGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAA 880
Query: 509 AKRQPRGRPSSSGTPRE-GPAGGTGGSGGPGGSLGSRGR 546
+ P G ++G P GPAG GG G P G G GR
Sbjct: 881 GRVGPPGPSGNAGPPGPPGPAGKEGGKG-PRGETGPAGR 918
Score = 35.0 bits (79), Expect = 0.80
Identities = 26/92 (28%), Positives = 34/92 (36%), Gaps = 17/92 (18%)
Query: 460 GAPGPTS-----GSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPR 514
GAPGP G+ G + P PT P G + G E + PR
Sbjct: 314 GAPGPAGARGNDGATGAAGPPGPT------------GPAGPPGFPGAVGAKGEAGPQGPR 361
Query: 515 GRPSSSGTPREGPAGGTGGSGGPGGSLGSRGR 546
G G E G G+ GP G+ G+ G+
Sbjct: 362 GSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQ 393
Score = 34.7 bits (78), Expect = 1.0
Identities = 41/134 (30%), Positives = 47/134 (35%), Gaps = 14/134 (10%)
Query: 421 RGPPGT----GLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPT--SGSQGQSQP 474
RGPPG GL L + D A A G PG +G+ GQ P
Sbjct: 244 RGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGP 303
Query: 475 SA-PTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPREGPAGGTGG 533
P + G A P GAR + G P G P G P A G G
Sbjct: 304 RGLPGERGRPG----APGPAGARGNDGATGAAGPPGPTGPAGPP---GFPGAVGAKGEAG 356
Query: 534 SGGPGGSLGSRGRR 547
GP GS G +G R
Sbjct: 357 PQGPRGSEGPQGVR 370
Score = 34.3 bits (77), Expect = 1.4
Identities = 34/125 (27%), Positives = 44/125 (35%), Gaps = 8/125 (6%)
Query: 417 AARRRGPPG-TGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQSQPS 475
AA R GPPG +G PP P A G PGP + + P
Sbjct: 879 AAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPG 938
Query: 476 APTTKLSSGTL--RSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPREGPAGGTGG 533
A + GT + + RG RG P G P ++GP+G +G
Sbjct: 939 ADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPG-----KQGPSGASGE 993
Query: 534 SGGPG 538
G PG
Sbjct: 994 RGPPG 998
Score = 33.1 bits (74), Expect = 3.0
Identities = 27/88 (30%), Positives = 31/88 (35%), Gaps = 17/88 (19%)
Query: 460 GAPGPTS--GSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRP 517
G PGP G +G+S PS P + P GAR RG G P
Sbjct: 770 GPPGPAGAPGDKGESGPSGP------------AGPTGARGAPGDRGEPGPPGPAGFAGPP 817
Query: 518 SSSGTPREGPAGGTGGSGGPGGSLGSRG 545
+ G P A G G G G G G
Sbjct: 818 GADGQPG---AKGEPGDAGAKGDAGPPG 842
Score = 33.1 bits (74), Expect = 3.0
Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 16/89 (17%)
Query: 460 GAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSS 519
G PGP SG G+ PS + + R P G P P ++ R+ G P +
Sbjct: 974 GLPGP-SGEPGKQGPSGASGE------RGPPGPMGP----PGLAGPPGESGRE--GAPGA 1020
Query: 520 SGTP-REGPAGGTGGSG--GPGGSLGSRG 545
G+P R+G G G G GP G G+ G
Sbjct: 1021 EGSPGRDGSPGAKGDRGETGPAGPPGAPG 1049
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 120 bits (301), Expect = 1e-26
Identities = 257/1029 (24%), Positives = 341/1029 (33%), Gaps = 173/1029 (16%)
Query: 903 PPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPVPSSSGRLTPSPRGGPFNPGSGGPL 962
PP + +R G ++ PP PP + +P GR + S G P P PL
Sbjct: 7 PPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPG--GRCSASI-GQPPLPA---PL 60
Query: 963 PASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPP-----------P 1011
P S +S PS P G+ H G L H A P
Sbjct: 61 PPSHGSSSGHPSKPYYAPGAPTPRPLH-GKLESLHGCVQALLREPAQPGLWEQLGQLYES 119
Query: 1012 QPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPS------ 1065
+ A + + GGS + PR+ Q L + G P
Sbjct: 120 EHDSEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNL 179
Query: 1066 -HHGSAGGGGGSSQGPALRYFQLPP---RAASAAMYVPARS------GRGRKGPLVKQTK 1115
H G GP ++ PP AA+ P+ G+ R+G +QT
Sbjct: 180 LHLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQT- 238
Query: 1116 VEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSS------G 1169
G P G LPP P P P P PPP P P + P S+ G
Sbjct: 239 --GLPP-GLPLPPPPLPPPPPPPPPPP----PPLPGLATSPPFQLTKPGLWSTLHGDAWG 291
Query: 1170 RSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSP--------VPPSPSPVPTPASPS 1221
+GS+ PP + E P+PA P PP P P P A
Sbjct: 292 PERKGSA----PPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESH 347
Query: 1222 G--PATLDFTSQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPG 1279
G PAT S + V +R + A + + G + ++
Sbjct: 348 GCLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSN 407
Query: 1280 PRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGAGS--RAYGGGGGSSAFTSFLPPRP 1337
LR + + G+ A+ Y S G G A S + + G ++ S LPP P
Sbjct: 408 TGLRGVEP-NPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLS-LPPGP 465
Query: 1338 LVHPLTG--KALDPASPLGLALAARERALKES----------SEGGGAPQPPPRPPSPRY 1385
P + L P P RA +E +EG P PPP P +
Sbjct: 466 SSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGF 525
Query: 1386 EAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPAS---PPAARR 1442
PP + H P +PP P +G S + P S PP R
Sbjct: 526 LGPPASRFSVGTQDSHTP------PTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLAR 579
Query: 1443 SL--LHRLP-----PTAPGVGPLLLQLGTEPPAP-HPGVSKPWRSAAPEEPERLPLHVRF 1494
S+ L R P P P + PL L L PP+ H S +R PE P V F
Sbjct: 580 SIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRR--PESPRP---RVSF 634
Query: 1495 LENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRASE--ENGLPLLVLPP--- 1549
P+ P E GPG PPP P S P P P E G L PP
Sbjct: 635 -----PKTP---------EVGPG-PPPGPL-SKAPQPVPPGVGELPARGPRLFDFPPTPL 678
Query: 1550 ------PAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLP----DTPAPA 1599
PA + DG ++ L + ++ E+ + P PP P +P P
Sbjct: 679 EDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPT 738
Query: 1600 TPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPA 1659
P PAVA T +T + T TQ P PP PP P P+
Sbjct: 739 DTAPTTTAPAVAVTTTTTTTTTT----------TATQEEEKKPPPALPPPPPLAKFPPPS 788
Query: 1660 APQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVA 1719
PQP P PPP S AS L SL++ G G GA V+
Sbjct: 789 QPQPPPPPPP----------------------SPASLLKSLASVLEGQKYCYRGTGAAVS 826
Query: 1720 SGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLM---TPSKLRGRALGASGG----LRPGP 1772
+ P L T Y G G ++ P P PS SGG R
Sbjct: 827 TRPGPLPT-TQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAG 885
Query: 1773 SGGLRDPVTPTS--PTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTA 1830
+ P+TPT P +S+ A ++ + T G A +P P A
Sbjct: 886 EEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPA 945
Query: 1831 SSLPRKLLP 1839
S +LLP
Sbjct: 946 DSGTERLLP 954
Score = 91.3 bits (225), Expect = 9e-18
Identities = 164/667 (24%), Positives = 222/667 (33%), Gaps = 138/667 (20%)
Query: 1334 PPRPLVHPLTGKALDPASPL---GLALAARERALKESSEGGGAPQPPPRPPSPRYEAPPP 1390
PP P PL G A P L GL A +G PP R+ P P
Sbjct: 257 PPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSA----PPERQEQRHSLPHP 312
Query: 1391 TPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAA---RRSLLHR 1447
P+ + H P RL A+PP P R G LPA+ P R S + R
Sbjct: 313 YPYPAPAYTAHPPGHRLVPAAPPGPGPRPPG-----AESHGCLPATRPPGSDLRESRVQR 367
Query: 1448 L---PPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLH----VRFLENCQP 1500
+P + P PG + S++ + + ++ Q
Sbjct: 368 SRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQT 427
Query: 1501 RAPVTS--GRGPPSEDGP-----GVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPS 1553
A S GR PS G P +P S+PP P+SP P L+ PPP P+
Sbjct: 428 PALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPP---CPRLLRPPPPPA 484
Query: 1554 --------VDVEDGEFLFV---------EPLPPPLEFSNSFEKP----------ESPLTP 1586
EDGE L P PPPL F P +S P
Sbjct: 485 WLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPP 544
Query: 1587 GPPHPLPDTP---------APATPLPPVPPPAVAAAPPTLDSTASSLTS-YDSEVATLTQ 1636
PP P + +PA P+ PPP +A + L S + D + LT
Sbjct: 545 TPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTL 604
Query: 1637 GASAAP---------GDPHPPGPPAPAAPAPAAPQPGPDPPPGTDS--------GIEEVD 1679
AP G P P P P P+ GP PPPG S G+ E+
Sbjct: 605 ALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELP 664
Query: 1680 SRSSS-----DHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDG 1734
+R PLE + +G +A+ ++LD + +
Sbjct: 665 ARGPRLFDFPPTPLEDQFEEPAEFKILPDG-------------LANIMKMLDESIRKEEE 711
Query: 1735 QAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGT 1794
Q + P PP + L+ + P+ + T T+ T +
Sbjct: 712 QQQHEAGVA--PQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEK 769
Query: 1795 DGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEG----------- 1843
AL PP +A P +P+ PP P P+ +SL + L EG
Sbjct: 770 KPPPAL-----PPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAA 824
Query: 1844 ----PGP------PPPPLPGPLAQPQASALATVKASIISELSSKLQQFGGSSAAGGALPW 1893
PGP P P G A P SA + + S SS Q S +GG PW
Sbjct: 825 VSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQ----FSTSGG--PW 878
Query: 1894 ARGGSGG 1900
AR G
Sbjct: 879 ARERRAG 885
Score = 82.8 bits (203), Expect = 3e-15
Identities = 189/785 (24%), Positives = 254/785 (32%), Gaps = 195/785 (24%)
Query: 900 YLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPVPSSSGRLTPSPRGGPFNPGSG 959
+L PPA +FS G++D PPT PP P +T S+SG + SP G
Sbjct: 525 FLGPPASRFS-----VGTQDSHTPPT--PPTP--TTSSSNSNSGSHSSSPAG-------- 567
Query: 960 GPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAH 1019
P SF P PP +S+ PLP PP + PP A
Sbjct: 568 -------PVSF--PPPP-----YLARSI---DPLP----RPPSPAQNPQDPPLVPLTLAL 606
Query: 1020 PPHPP---EMETGGS---PDDPPPRLALGPQPSLRGWRGGGPSPTPG----APSPSHHGS 1069
PP PP T GS P+ P PR++ P + GP P PG AP P
Sbjct: 607 PPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEV------GPGPPPGPLSKAPQPV---P 657
Query: 1070 AGGGGGSSQGPALRYFQLPPRAASAAMYVPAR-----SGRGRKGPLVKQT--KVEGEPQK 1122
G G ++GP R F PP PA G ++ ++ K E + Q
Sbjct: 658 PGVGELPARGP--RLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQH 715
Query: 1123 GGGLPPAPSPTSP-ASPQPP-PAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAE 1180
G+ P P P AS Q P P AP + P + + +T+++ ++ +
Sbjct: 716 EAGVAPQPPLKEPFASLQSPFPTDTAP----TTTAPAVAVTTTTTTTTTTTATQEEEKKP 771
Query: 1181 PPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPSPVPTPASPSGPATLDFTSQFGAALVGA- 1239
PP P P P ++ PP P P P P PA+L + L G
Sbjct: 772 PPALP--------------PPPPLAKFPPPSQPQPPPPPPPSPASL--LKSLASVLEGQK 815
Query: 1240 -ARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPY 1298
R G R G G T AAP + P
Sbjct: 816 YCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQ-------------GSPQ 862
Query: 1299 LRLESAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRP--------------------- 1337
S+ + GG A R G T PP P
Sbjct: 863 PSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACE 922
Query: 1338 -LVHPLTGKALDPASPLGLALAA---RERAL---KESSEGGGAPQPPPRPPSPRYEAPPP 1390
LV + A DPA P+ A A ER L + E GG + E
Sbjct: 923 TLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKRRQKE---- 978
Query: 1391 TPHHHSPHAHH-------------EPVLRLWGASPPDPARRELG--------------YR 1423
H H H E + P + +RR LG R
Sbjct: 979 ---HQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSR 1035
Query: 1424 AGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSK----PWRS 1479
LG K+ P + PA + PT P + E P P PGVS+ RS
Sbjct: 1036 PDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPGP-PGVSRADMLKLRS 1094
Query: 1480 AAPEEPERLPLHVRFLENCQPRAPVTS---------GRGPPSEDGPGVPPPSPRRSV--- 1527
+ P+ L + + +E+ + S S V S V
Sbjct: 1095 LSEGPPKELKIRLIKVESGDKETFIASEVEERRLRMADLTISHCAADVVRASRNAKVKGK 1154
Query: 1528 -------PPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKP 1580
P P+ + E LP L PP PS+ +E F P L+F P
Sbjct: 1155 FRESYLSPAQSVKPKINTEEKLPREKLNPPTPSIYLESKRDAF---SPVLLQFCTD---P 1208
Query: 1581 ESPLT 1585
+P+T
Sbjct: 1209 RNPIT 1213
Score = 78.6 bits (192), Expect = 6e-14
Identities = 210/857 (24%), Positives = 284/857 (33%), Gaps = 229/857 (26%)
Query: 1345 KALDPASPLGLALAARERALKESSEGGGA-----PQPPPR---------------PPSPR 1384
+A+DP A AARE GA P PPPR PP P
Sbjct: 3 RAVDPPG----ARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLP- 57
Query: 1385 YEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAARRSL 1444
AP P P H S H GA P P +L +SL A R
Sbjct: 58 --APLP-PSHGSSSGHPSKPYYAPGAPTPRPLHGKL----------ESLHGCVQALLRE- 103
Query: 1445 LHRLPPTAPGVGPLLLQL------GTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLEN- 1497
P PG+ L QL E + + S A P L L N
Sbjct: 104 -----PAQPGLWEQLGQLYESEHDSEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNF 158
Query: 1498 ----CQPRAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSP---RASEENGLPLLVLPPP 1550
CQ RA V PP E + +R+ P RA+E P +V P P
Sbjct: 159 HTGSCQHRAKVL----PPLEQVWNLLHLEHKRNYGAKRGGPPVKRAAE----PPVVQPVP 210
Query: 1551 APSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPP-- 1608
++ GE E L P + ++ L PG P P P P P P PP PPP
Sbjct: 211 PAALSGPSGE----EGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPPPPPPPPLP 266
Query: 1609 AVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGD--------PHPPGPPAPAAPA--- 1657
+A +PP T L S A + +AP + PHP PAPA A
Sbjct: 267 GLATSPP-FQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPAYTAHPP 325
Query: 1658 -----PAAPQPGPDP-PPGTDS----------GIEEVDSRSSSDHPLETISSASTL---- 1697
PAAP PGP P PPG +S G + +SR ++S A+T
Sbjct: 326 GHRLVPAAP-PGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVP 384
Query: 1698 ----------------SSLSAEGGGSAG---GGGGAGAGVASGPELLDTYVAYLDGQAFG 1738
SS S+ G G G GA P L ++ L A
Sbjct: 385 YAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHS 444
Query: 1739 -------------------GSSTPGPPYPPQLMTPSK----LRGRA-------------- 1761
G S+P PP P+L+ P L+G A
Sbjct: 445 SRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEEL 504
Query: 1762 -LGASGGLRPGP-----------------SGGLRDPVTPTSPTVSVTGAGTDGLLALRAC 1803
G G RP P S G +D TP +P T +
Sbjct: 505 FFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSN------- 557
Query: 1804 SGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPP--------PPPLPGPL 1855
SG ++ AG PV+ P PP + LPR P + PP PP P
Sbjct: 558 SGSHSSSPAG-PVSFPP--PPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSC 614
Query: 1856 AQPQASALATVKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYVPER 1915
Q + + ++ K + G G + G G+ G
Sbjct: 615 HQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFP 674
Query: 1916 TSSLQRQ-------RLSDDSQSSLLSKPVSSLFQNW----------PKPPLP-------- 1950
+ L+ Q ++ D ++++ S+ + P+PPL
Sbjct: 675 PTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQS 734
Query: 1951 PLPTGTGVSPTAAAAPGATSPSASSSSTSTRHLQGVEFEMRPPLLRRAPSP--SLLPASE 2008
P PT T + TA A T+ + ++++T+T+ E E +PP P P P S+
Sbjct: 735 PFPTDTAPTTTAPAVAVTTTTTTTTTTTATQ-----EEEKKPPPALPPPPPLAKFPPPSQ 789
Query: 2009 HKVSPAPRPSSLPILPS 2025
+ P P PS +L S
Sbjct: 790 PQPPPPPPPSPASLLKS 806
Score = 59.7 bits (143), Expect = 3e-08
Identities = 104/413 (25%), Positives = 125/413 (30%), Gaps = 112/413 (27%)
Query: 864 PHHRAQPSYERPSFLPPGPGLMLRQKSIGAAEDD-RPYLAPPAMKFSRSLSVPGSEDIPP 922
P HR P+ PPGPG + GA P PP S D
Sbjct: 325 PGHRLVPA------APPGPG----PRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSV 374
Query: 923 PPTTSPPEPPYSTPPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGS 982
P + PY+ P G T S N G G P D P V
Sbjct: 375 SPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVS- 433
Query: 983 REKSLYHSGPLPPAHHH-----------PPH---HHHHHAPPPQPHHHHAHPPHPPEMET 1028
H G L P+ H PH +PPP P PP PP
Sbjct: 434 ------HHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLK 487
Query: 1029 GGS----------------PDDPPPRLALGPQPSLRGWRGGGPS------------PTPG 1060
G + + PPR A P P G+ G S PTP
Sbjct: 488 GPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTP- 546
Query: 1061 APSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEP 1120
P+P+ S G S PA PP P
Sbjct: 547 -PTPTTSSSNSNSGSHSSSPAGPVSFPPP------------------------------P 575
Query: 1121 QKGGGLPPAPSPTSPA-SPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEA 1179
+ P P P SPA +PQ PP V P+ + AP SS +++ GS
Sbjct: 576 YLARSIDPLPRPPSPAQNPQDPPLV---------PLTLALPPAP-PSSCHQNTSGSFRRP 625
Query: 1180 EPPTQPE---PTGGGGGGGSSPSP-APAMSPVPPSPSPVPTPASPSGPATLDF 1228
E P +P P G G P P + A PVPP +P GP DF
Sbjct: 626 ESP-RPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPA----RGPRLFDF 673
Score = 45.4 bits (106), Expect = 6e-04
Identities = 116/497 (23%), Positives = 157/497 (31%), Gaps = 86/497 (17%)
Query: 1603 PPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQ 1662
PP PPP A P S + + + +S P P+ AP AP P
Sbjct: 32 PPHPPPRSAWLPGGRCSASIGQPPLPAPLPPSHGSSSGHPSKPYY----APGAPTPRPLH 87
Query: 1663 PGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGP 1722
+ G + ++ L + + S + SA GG+ A + GP
Sbjct: 88 GKLESLHGCVQALLREPAQPGLWEQLGQLYESEHDSEEATRCYHSALRYGGSFAEL--GP 145
Query: 1723 ELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGP--SGGLRDPV 1780
+ A L G PP + L G R GP PV
Sbjct: 146 RIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWNLLHLEHKRNYGAKRGGPPVKRAAEPPV 205
Query: 1781 TPTSPTVSVTG-AGTDGLLA----LRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPR 1835
P +++G +G +GL R C+ T G P+ PP PLP
Sbjct: 206 VQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPL------PPPPLP------- 252
Query: 1836 KLLPWEEGPGPPPPPLPGPLAQPQASALATVKASIISELSSKLQQFGGSSAAGGA----- 1890
P P PPPPPLPG P K + S L G G A
Sbjct: 253 ---PPPPPPPPPPPPLPGLATSPP---FQLTKPGLWSTLHGDAW---GPERKGSAPPERQ 303
Query: 1891 --------------------------LPWARGGSGGG--GDSHHGGASYVPERTSSLQRQ 1922
+P A G G G HG S L+
Sbjct: 304 EQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRES 363
Query: 1923 RLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGVSPTAAAAPGATSPSASSSSTSTRH 1982
R+ Q S + VS P P P G PG T+ S+SSSS+S
Sbjct: 364 RV----QRSRMDSSVSPAATTACVPYAPSRPPGL---------PGTTT-SSSSSSSSNTG 409
Query: 1983 LQGVEFEMRPPLLRRAPSPSLLPASEHKVSPAPRPSSLPILPSGPLYPGLFDIRGSPTGG 2042
L+GVE P +P+L + ++ P+ S P L + P L P G
Sbjct: 410 LRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHL----SLPPGP 465
Query: 2043 AGGSADPFAPVFVPPHP 2059
+ P + PP P
Sbjct: 466 SSPPPPPCPRLLRPPPP 482
Score = 42.7 bits (99), Expect = 0.004
Identities = 89/429 (20%), Positives = 128/429 (29%), Gaps = 87/429 (20%)
Query: 841 PGGLASLGKHRPKGFFATESSFDPHHRAQPSYERPSFLPPGPGLMLRQKSIGAAEDDRPY 900
P GLA++ K + E P +P P L + A P
Sbjct: 692 PDGLANIMKMLDESIRKEEEQQQHEAGVAP---QPPLKEPFASLQSPFPTDTAPTTTAPA 748
Query: 901 LAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPVPSSSGRLTPSPRGGPFNPGSGG 960
+A + + + E+ PP PP PP + P PS P+ P P S
Sbjct: 749 VAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPS-------QPQPPPPPPPSPA 801
Query: 961 PLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHP 1020
L S + +G G+ + GPLP + P PP
Sbjct: 802 SLLKSLASVLEGQKYCYRGTGAAVST--RPGPLPTTQYSP-------GPP------SGAT 846
Query: 1021 PHPPEMETGGSPDDPPPRLALGPQPSLRG--W---RGGGPSPTPGAPSPSHHGSAGGGGG 1075
PP + P P + Q S G W R G P PG +P+
Sbjct: 847 ALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPP----- 901
Query: 1076 SSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGG---LPPAPSP 1132
S PA ++ + A + R GR P EP G LPPA +
Sbjct: 902 LSLPPARSESEVLEEISRACETLVERVGRSATDP--ADPVDTAEPADSGTERLLPPAQAK 959
Query: 1133 TS------------------------------------PASPQPPPAVAAPSEKNSIPIP 1156
P + P EK+ +
Sbjct: 960 EEAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLG 1019
Query: 1157 TIIIKAPSTS--SSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPSPV 1214
+ +++ R G +++A+PPT P P +PAP+ P PPS S
Sbjct: 1020 NLDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPS---------APAPSAQPTPPSASVP 1070
Query: 1215 PTPASPSGP 1223
A P
Sbjct: 1071 GKKAREEAP 1079
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 116 bits (291), Expect = 2e-25
Identities = 144/520 (27%), Positives = 188/520 (36%), Gaps = 140/520 (26%)
Query: 1206 PVPPSPSPVPTPASPSGPATLDFTSQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDE 1265
PVPP P+P P P A E N+ E
Sbjct: 2 PVPPPPAPPPPPT------------------FALANTEKPTLNKT--------------E 29
Query: 1266 DGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGAGSRAYGGGGG 1325
G L + + G +L+ + + D SA + + AG+G G GG+G G +GGGGG
Sbjct: 30 QAGRNALLSDISKGKKLKKTVTNDR---SAPILDKPKGAGAGGGGGGFGGGG-GFGGGGG 85
Query: 1326 SSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKESSEGGGAP----------- 1374
SF P P G P R A +++ GG P
Sbjct: 86 GGGGGSFGGGGP---PGLGGLFQAGMP-----KLRSTANRDNDSGGSRPPLLPPGGRSTS 137
Query: 1375 QPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARREL-GYRAGLGSQEKSL 1433
P PPS P P+P H S PP+P R + R +GS+ S+
Sbjct: 138 AKPFSPPSGPGRFPVPSPGHRS--------------GPPEPQRNRMPPPRPDVGSKPDSI 183
Query: 1434 PASPPAARRSLL----HRLPPTAPGVGPLLLQLGTEPPAPHPG-----------VSKPWR 1478
P P+ R + +R P PG GP G PP P PG P
Sbjct: 184 PPPVPSTPRPIQSSPHNRGSPPVPG-GPRQPSPGPTPP-PFPGNRGTALGGGSIRQSPLS 241
Query: 1479 SAAP--EEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRA 1536
S++P P P R L++ P P G PS VPPP P+ + PP P++PR
Sbjct: 242 SSSPFSNRPPLPPTPSRALDDKPPPPPPPVG-NRPSIHREAVPPPPPQNNKPPVPSTPRP 300
Query: 1537 SEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNS--FEKPESPL---------- 1584
S + P PPP PS P PPPL S+S E P P
Sbjct: 301 SASSQAP---PPPPPPS-----------RPGPPPLPPSSSGNDETPRLPQRNLSLSSSTP 346
Query: 1585 ---TPGPPHPLPDTPAPATPLP---------PVPPPAVAAAPPTLDSTASSLTSYDSEVA 1632
+PG PLP P+ P P P+PPP PP + ++S +
Sbjct: 347 PLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPP-----PPVSRNGSTSRALPATPQL 401
Query: 1633 TLTQGASAAPGDPHPPGPP-APAAPAPAAPQPGPDPPPGT 1671
G + P PP PP P+A AP P PPP T
Sbjct: 402 PSRSGVDSPRSGPRPPLPPDRPSAGAP------PPPPPST 435
Score = 92.0 bits (227), Expect = 5e-18
Identities = 112/412 (27%), Positives = 143/412 (34%), Gaps = 90/412 (21%)
Query: 840 GPGGLASLGKHRPKGFFATESSFDPHHRAQPSYE------RPSFLPPGPGLMLRQKSIGA 893
G GG S G P G + P R+ + + RP LPPG G
Sbjct: 85 GGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPG----------GR 134
Query: 894 AEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTTS---PPEPPYST------PPVPSSSGR 944
+ +P+ +PP+ + PG PP P + PP P + PPVPS+
Sbjct: 135 STSAKPF-SPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRP 193
Query: 945 LTPSP--RGGPFNPGSGG-PLPASSPASFDGPSPPDTRVGS-REKSLYHSGPL---PPAH 997
+ SP RG P PG P P +P F G GS R+ L S P PP
Sbjct: 194 IQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLP 253
Query: 998 HHPPHHHHHHAPPPQPH-------HHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGW 1050
P PPP P H A PP PP+ P P P + P
Sbjct: 254 PTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPP----- 308
Query: 1051 RGGGPSPTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPL 1110
P P P P P + G + +LP R S + P GR GPL
Sbjct: 309 ----PPPPPSRPGPPPLPPSSSGNDETP-------RLPQRNLSLSSSTPPLPSPGRSGPL 357
Query: 1111 VKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGR 1170
PP PS P + PP + P +P P +
Sbjct: 358 ----------------PPPPSERPPPPVRDPPGRSGP-----LPPPPPV----------- 385
Query: 1171 SSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSP-SPVPTPASPS 1221
S GS++ A P T P+ G S P P + P PS +P P P S S
Sbjct: 386 SRNGSTSRALPATPQLPSRSGVDSPRS-GPRPPLPPDRPSAGAPPPPPPSTS 436
Score = 82.8 bits (203), Expect = 3e-15
Identities = 129/488 (26%), Positives = 153/488 (31%), Gaps = 98/488 (20%)
Query: 1642 PGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLS 1701
P P PP PP A P G ++ + ++ + SA L
Sbjct: 4 PPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILDKPK 63
Query: 1702 AEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRA 1761
G G GGG G G G G G +FGG PG Q P KLR A
Sbjct: 64 GAGAGGGGGGFGGGGGFGGGG-------GGGGGGSFGGGGPPGLGGLFQAGMP-KLRSTA 115
Query: 1762 L--GASGGLRPG--PSGGLRDPVTPTSP-------TVSVTGAGTDGLLALRACSGPPTAG 1810
SGG RP P GG P SP V G + R PP
Sbjct: 116 NRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPD 175
Query: 1811 VAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLAQPQASALATVKASI 1870
V P ++ P VP P P SS + P PG P P PGP P
Sbjct: 176 VGSKPDSIPPPVPSTPRPIQSSPHNRGSP--PVPGGPRQPSPGPTPPP------------ 221
Query: 1871 ISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQRQRLSDDSQS 1930
P RG + GGG S+++ LS S
Sbjct: 222 --------------------FPGNRGTALGGG---------------SIRQSPLSSSSPF 246
Query: 1931 S----LLSKPVSSLFQNWPKPPLPPLPTGTGVSPTAAAAPGATSPSASSSSTSTRHLQGV 1986
S L P +L KPP PP P G S A P + ST
Sbjct: 247 SNRPPLPPTPSRALDD---KPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSAS 303
Query: 1987 EFEMRPPLLRRAPSPSLLPASEHKVSPAPR--------PSSLPILP----SGPLYPGLFD 2034
PP P P LP S PR SS P LP SGPL P +
Sbjct: 304 SQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSE 363
Query: 2035 IRGSPTGGAGGSADPFAPVFVPPHPGISGGLGGALSGASRSLSPTRLLS--------LPP 2086
P G + P P PP +G AL + S + + S LPP
Sbjct: 364 RPPPPVRDPPGRSGPLPP---PPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPP 420
Query: 2087 DKPFGAKP 2094
D+P P
Sbjct: 421 DRPSAGAP 428
Score = 78.6 bits (192), Expect = 6e-14
Identities = 89/331 (26%), Positives = 114/331 (34%), Gaps = 67/331 (20%)
Query: 951 GGPFNPGSGGPLPASSP-----ASFD----GPSPPDTRVGSREKSLYHSGPLPPAHHHPP 1001
GGP PG GG A P A+ D G PP G R S P P
Sbjct: 95 GGP--PGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPV 152
Query: 1002 HHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGA 1061
H + PP+P + PP P + G PD PP + P+P G P PG
Sbjct: 153 PSPGHRSGPPEPQRNRMPPPRP---DVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGG 209
Query: 1062 PS-----------PSHHGSAGGGGG------SSQGPALRYFQLPPRAASAA--------- 1095
P P + G+A GGG SS P LPP + A
Sbjct: 210 PRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPP 269
Query: 1096 ----------MYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVA 1145
VP + K P+ + Q PP P P+ P P PP+ +
Sbjct: 270 PVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAP---PPPPPPSRPGPPPLPPSSS 326
Query: 1146 APSEKNSIPIPTIIIKA--PSTSSSGRSS--QGSSTEAEPPTQPEPTGGGG--------- 1192
E +P + + + P S GRS +E PP +P G G
Sbjct: 327 GNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVS 386
Query: 1193 GGGSSPSPAPAMSPVPPSPSPVPTPASPSGP 1223
GS+ PA +P PS S V +P S P
Sbjct: 387 RNGSTSRALPA-TPQLPSRSGVDSPRSGPRP 416
Score = 53.5 bits (127), Expect = 2e-06
Identities = 89/354 (25%), Positives = 112/354 (31%), Gaps = 77/354 (21%)
Query: 1507 GRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEP 1566
G GPP G RS T+ R ++ G +LPP S + P
Sbjct: 94 GGGPPGLGGLFQAGMPKLRS-----TANRDNDSGGSRPPLLPPGGRSTSAK--------P 140
Query: 1567 LPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLTS 1626
PP F P GPP P + P P P ++ PP + ST + S
Sbjct: 141 FSPP-SGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSI---PPPVPSTPRPIQS 196
Query: 1627 YDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDH 1686
PH G P P P P PGP PPP + + S
Sbjct: 197 -----------------SPHNRGSP-PVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQS 238
Query: 1687 PLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPP 1746
PL SS+S S+ P L T LD + P PP
Sbjct: 239 PL---SSSSPFSNR---------------------PPLPPTPSRALDDK-------PPPP 267
Query: 1747 YPPQLMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGP 1806
PP PS R P P P P++P S + + GP
Sbjct: 268 PPPVGNRPSIHREAV--------PPPPPQNNKPPVPSTPRPSASSQAPPPPPP-PSRPGP 318
Query: 1807 PTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPP--LPGPLAQP 1858
P + P +P L +SS P P GP PPPP P P+ P
Sbjct: 319 PPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDP 372
Score = 50.8 bits (120), Expect = 1e-05
Identities = 66/214 (30%), Positives = 80/214 (37%), Gaps = 43/214 (20%)
Query: 1048 RGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQG---PAL-RYFQL-PPRAASAAMYVPARS 1102
+G GG G G GGGGGS G P L FQ P+ S A
Sbjct: 63 KGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTAN--RDND 120
Query: 1103 GRGRKGPLV----KQTKVEG-EPQKGGGLPPAPSP---TSPASPQ----PPPAVAAPSEK 1150
G + PL+ + T + P G G P PSP + P PQ PPP S+
Sbjct: 121 SGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKP 180
Query: 1151 NSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEP----------TGGGGGGG----- 1195
+SIP P + P S ++GS P QP P G GGG
Sbjct: 181 DSIPPP--VPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQS 238
Query: 1196 --SSPSPAPAMSPVPPSPSPV-----PTPASPSG 1222
SS SP P+PP+PS P P P G
Sbjct: 239 PLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVG 272
Score = 47.8 bits (112), Expect = 1e-04
Identities = 79/270 (29%), Positives = 92/270 (34%), Gaps = 50/270 (18%)
Query: 1603 PPVPPPAVAAAPPTLDSTAS-SLTSYDSEVATLTQGA---SAAPGDPHPPGP-----PAP 1653
PP A P L STA+ S S L G SA P P P GP P+P
Sbjct: 97 PPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSP-PSGPGRFPVPSP 155
Query: 1654 A-APAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAGGGG 1712
P PQ PPP D G S+ S P + SS G GG
Sbjct: 156 GHRSGPPEPQRNRMPPPRPDVG-----SKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGP 210
Query: 1713 GAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGP 1772
+ + P G A GG S P L + S R L P P
Sbjct: 211 RQPSPGPTPPPFPGNR-----GTALGGGSIRQSP----LSSSSPFSNRP-----PLPPTP 256
Query: 1773 SGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASS 1832
S L D P P V G + A PP P +P VP P P+ASS
Sbjct: 257 SRALDDKPPPPPPPV-----GNRPSIHREAVPPPP-------PQNNKPPVPSTPRPSASS 304
Query: 1833 LPRKLLPWEEGPGPPPPPLPGPLAQPQASA 1862
+ P PPPP PGP P +S+
Sbjct: 305 --------QAPPPPPPPSRPGPPPLPPSSS 326
Score = 43.5 bits (101), Expect = 0.002
Identities = 73/275 (26%), Positives = 92/275 (33%), Gaps = 43/275 (15%)
Query: 1838 LPWEEGPGPPPPPLPGPLAQPQASALATVKA---SIISELSSK---------------LQ 1879
+P P PPPPP + + T +A +++S++S L
Sbjct: 1 MPVPPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILD 60
Query: 1880 QFGGSSAAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQRQRLSDDSQSSLLSKPVSS 1939
+ G+ A GG + GG GGG GG S+ L L L S
Sbjct: 61 KPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGL--GGLFQAGMPKLRSTANRD 118
Query: 1940 LFQNWPKPPLPPLPTGTGVSPTAAAAPGATSPSASSSSTSTRHLQGVEFEMRPPLLRRAP 1999
+PPL P P G S + P S S H G P R P
Sbjct: 119 NDSGGSRPPLLP-PGGRSTSAKPFSPP---SGPGRFPVPSPGHRSGPP----EPQRNRMP 170
Query: 2000 SPSLLPASEHKVSPAPRPSSLPILPSGPLYPGLFDIRGSPTGGAGGSADPFAPVFVPPHP 2059
P S+ P P PS+ + S P RGSP GG P PP P
Sbjct: 171 PPRPDVGSKPDSIPPPVPSTPRPIQSSP------HNRGSPP-VPGGPRQPSPGPTPPPFP 223
Query: 2060 GISGGLGGALSGASRSLSPTRLLSLPPDKPFGAKP 2094
G G AL G S SP L PF +P
Sbjct: 224 ---GNRGTALGGGSIRQSP-----LSSSSPFSNRP 250
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 116 bits (291), Expect = 2e-25
Identities = 144/520 (27%), Positives = 188/520 (36%), Gaps = 140/520 (26%)
Query: 1206 PVPPSPSPVPTPASPSGPATLDFTSQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDE 1265
PVPP P+P P P A E N+ E
Sbjct: 2 PVPPPPAPPPPPT------------------FALANTEKPTLNKT--------------E 29
Query: 1266 DGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGAGSRAYGGGGG 1325
G L + + G +L+ + + D SA + + AG+G G GG+G G +GGGGG
Sbjct: 30 QAGRNALLSDISKGKKLKKTVTNDR---SAPILDKPKGAGAGGGGGGFGGGG-GFGGGGG 85
Query: 1326 SSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKESSEGGGAP----------- 1374
SF P P G P R A +++ GG P
Sbjct: 86 GGGGGSFGGGGP---PGLGGLFQAGMP-----KLRSTANRDNDSGGSRPPLLPPGGRSTS 137
Query: 1375 QPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARREL-GYRAGLGSQEKSL 1433
P PPS P P+P H S PP+P R + R +GS+ S+
Sbjct: 138 AKPFSPPSGPGRFPVPSPGHRS--------------GPPEPQRNRMPPPRPDVGSKPDSI 183
Query: 1434 PASPPAARRSLL----HRLPPTAPGVGPLLLQLGTEPPAPHPG-----------VSKPWR 1478
P P+ R + +R P PG GP G PP P PG P
Sbjct: 184 PPPVPSTPRPIQSSPHNRGSPPVPG-GPRQPSPGPTPP-PFPGNRGTALGGGSIRQSPLS 241
Query: 1479 SAAP--EEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRA 1536
S++P P P R L++ P P G PS VPPP P+ + PP P++PR
Sbjct: 242 SSSPFSNRPPLPPTPSRALDDKPPPPPPPVG-NRPSIHREAVPPPPPQNNKPPVPSTPRP 300
Query: 1537 SEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNS--FEKPESPL---------- 1584
S + P PPP PS P PPPL S+S E P P
Sbjct: 301 SASSQAP---PPPPPPS-----------RPGPPPLPPSSSGNDETPRLPQRNLSLSSSTP 346
Query: 1585 ---TPGPPHPLPDTPAPATPLP---------PVPPPAVAAAPPTLDSTASSLTSYDSEVA 1632
+PG PLP P+ P P P+PPP PP + ++S +
Sbjct: 347 PLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPP-----PPVSRNGSTSRALPATPQL 401
Query: 1633 TLTQGASAAPGDPHPPGPP-APAAPAPAAPQPGPDPPPGT 1671
G + P PP PP P+A AP P PPP T
Sbjct: 402 PSRSGVDSPRSGPRPPLPPDRPSAGAP------PPPPPST 435
Score = 92.0 bits (227), Expect = 5e-18
Identities = 112/412 (27%), Positives = 143/412 (34%), Gaps = 90/412 (21%)
Query: 840 GPGGLASLGKHRPKGFFATESSFDPHHRAQPSYE------RPSFLPPGPGLMLRQKSIGA 893
G GG S G P G + P R+ + + RP LPPG G
Sbjct: 85 GGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPG----------GR 134
Query: 894 AEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTTS---PPEPPYST------PPVPSSSGR 944
+ +P+ +PP+ + PG PP P + PP P + PPVPS+
Sbjct: 135 STSAKPF-SPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRP 193
Query: 945 LTPSP--RGGPFNPGSGG-PLPASSPASFDGPSPPDTRVGS-REKSLYHSGPL---PPAH 997
+ SP RG P PG P P +P F G GS R+ L S P PP
Sbjct: 194 IQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLP 253
Query: 998 HHPPHHHHHHAPPPQPH-------HHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGW 1050
P PPP P H A PP PP+ P P P + P
Sbjct: 254 PTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPP----- 308
Query: 1051 RGGGPSPTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPL 1110
P P P P P + G + +LP R S + P GR GPL
Sbjct: 309 ----PPPPPSRPGPPPLPPSSSGNDETP-------RLPQRNLSLSSSTPPLPSPGRSGPL 357
Query: 1111 VKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGR 1170
PP PS P + PP + P +P P +
Sbjct: 358 ----------------PPPPSERPPPPVRDPPGRSGP-----LPPPPPV----------- 385
Query: 1171 SSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSP-SPVPTPASPS 1221
S GS++ A P T P+ G S P P + P PS +P P P S S
Sbjct: 386 SRNGSTSRALPATPQLPSRSGVDSPRS-GPRPPLPPDRPSAGAPPPPPPSTS 436
Score = 82.8 bits (203), Expect = 3e-15
Identities = 129/488 (26%), Positives = 153/488 (31%), Gaps = 98/488 (20%)
Query: 1642 PGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLS 1701
P P PP PP A P G ++ + ++ + SA L
Sbjct: 4 PPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILDKPK 63
Query: 1702 AEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRA 1761
G G GGG G G G G G +FGG PG Q P KLR A
Sbjct: 64 GAGAGGGGGGFGGGGGFGGGG-------GGGGGGSFGGGGPPGLGGLFQAGMP-KLRSTA 115
Query: 1762 L--GASGGLRPG--PSGGLRDPVTPTSP-------TVSVTGAGTDGLLALRACSGPPTAG 1810
SGG RP P GG P SP V G + R PP
Sbjct: 116 NRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPD 175
Query: 1811 VAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLAQPQASALATVKASI 1870
V P ++ P VP P P SS + P PG P P PGP P
Sbjct: 176 VGSKPDSIPPPVPSTPRPIQSSPHNRGSP--PVPGGPRQPSPGPTPPP------------ 221
Query: 1871 ISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQRQRLSDDSQS 1930
P RG + GGG S+++ LS S
Sbjct: 222 --------------------FPGNRGTALGGG---------------SIRQSPLSSSSPF 246
Query: 1931 S----LLSKPVSSLFQNWPKPPLPPLPTGTGVSPTAAAAPGATSPSASSSSTSTRHLQGV 1986
S L P +L KPP PP P G S A P + ST
Sbjct: 247 SNRPPLPPTPSRALDD---KPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSAS 303
Query: 1987 EFEMRPPLLRRAPSPSLLPASEHKVSPAPR--------PSSLPILP----SGPLYPGLFD 2034
PP P P LP S PR SS P LP SGPL P +
Sbjct: 304 SQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSE 363
Query: 2035 IRGSPTGGAGGSADPFAPVFVPPHPGISGGLGGALSGASRSLSPTRLLS--------LPP 2086
P G + P P PP +G AL + S + + S LPP
Sbjct: 364 RPPPPVRDPPGRSGPLPP---PPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPP 420
Query: 2087 DKPFGAKP 2094
D+P P
Sbjct: 421 DRPSAGAP 428
Score = 78.6 bits (192), Expect = 6e-14
Identities = 89/331 (26%), Positives = 114/331 (34%), Gaps = 67/331 (20%)
Query: 951 GGPFNPGSGGPLPASSP-----ASFD----GPSPPDTRVGSREKSLYHSGPLPPAHHHPP 1001
GGP PG GG A P A+ D G PP G R S P P
Sbjct: 95 GGP--PGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPV 152
Query: 1002 HHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGA 1061
H + PP+P + PP P + G PD PP + P+P G P PG
Sbjct: 153 PSPGHRSGPPEPQRNRMPPPRP---DVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGG 209
Query: 1062 PS-----------PSHHGSAGGGGG------SSQGPALRYFQLPPRAASAA--------- 1095
P P + G+A GGG SS P LPP + A
Sbjct: 210 PRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPP 269
Query: 1096 ----------MYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVA 1145
VP + K P+ + Q PP P P+ P P PP+ +
Sbjct: 270 PVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAP---PPPPPPSRPGPPPLPPSSS 326
Query: 1146 APSEKNSIPIPTIIIKA--PSTSSSGRSS--QGSSTEAEPPTQPEPTGGGG--------- 1192
E +P + + + P S GRS +E PP +P G G
Sbjct: 327 GNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVS 386
Query: 1193 GGGSSPSPAPAMSPVPPSPSPVPTPASPSGP 1223
GS+ PA +P PS S V +P S P
Sbjct: 387 RNGSTSRALPA-TPQLPSRSGVDSPRSGPRP 416
Score = 53.5 bits (127), Expect = 2e-06
Identities = 89/354 (25%), Positives = 112/354 (31%), Gaps = 77/354 (21%)
Query: 1507 GRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEP 1566
G GPP G RS T+ R ++ G +LPP S + P
Sbjct: 94 GGGPPGLGGLFQAGMPKLRS-----TANRDNDSGGSRPPLLPPGGRSTSAK--------P 140
Query: 1567 LPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLTS 1626
PP F P GPP P + P P P ++ PP + ST + S
Sbjct: 141 FSPP-SGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSI---PPPVPSTPRPIQS 196
Query: 1627 YDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDH 1686
PH G P P P P PGP PPP + + S
Sbjct: 197 -----------------SPHNRGSP-PVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQS 238
Query: 1687 PLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPP 1746
PL SS+S S+ P L T LD + P PP
Sbjct: 239 PL---SSSSPFSNR---------------------PPLPPTPSRALDDK-------PPPP 267
Query: 1747 YPPQLMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGP 1806
PP PS R P P P P++P S + + GP
Sbjct: 268 PPPVGNRPSIHREAV--------PPPPPQNNKPPVPSTPRPSASSQAPPPPPP-PSRPGP 318
Query: 1807 PTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPP--LPGPLAQP 1858
P + P +P L +SS P P GP PPPP P P+ P
Sbjct: 319 PPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDP 372
Score = 50.8 bits (120), Expect = 1e-05
Identities = 66/214 (30%), Positives = 80/214 (37%), Gaps = 43/214 (20%)
Query: 1048 RGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQG---PAL-RYFQL-PPRAASAAMYVPARS 1102
+G GG G G GGGGGS G P L FQ P+ S A
Sbjct: 63 KGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTAN--RDND 120
Query: 1103 GRGRKGPLV----KQTKVEG-EPQKGGGLPPAPSP---TSPASPQ----PPPAVAAPSEK 1150
G + PL+ + T + P G G P PSP + P PQ PPP S+
Sbjct: 121 SGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKP 180
Query: 1151 NSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEP----------TGGGGGGG----- 1195
+SIP P + P S ++GS P QP P G GGG
Sbjct: 181 DSIPPP--VPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQS 238
Query: 1196 --SSPSPAPAMSPVPPSPSPV-----PTPASPSG 1222
SS SP P+PP+PS P P P G
Sbjct: 239 PLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVG 272
Score = 47.8 bits (112), Expect = 1e-04
Identities = 79/270 (29%), Positives = 92/270 (34%), Gaps = 50/270 (18%)
Query: 1603 PPVPPPAVAAAPPTLDSTAS-SLTSYDSEVATLTQGA---SAAPGDPHPPGP-----PAP 1653
PP A P L STA+ S S L G SA P P P GP P+P
Sbjct: 97 PPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSP-PSGPGRFPVPSP 155
Query: 1654 A-APAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAGGGG 1712
P PQ PPP D G S+ S P + SS G GG
Sbjct: 156 GHRSGPPEPQRNRMPPPRPDVG-----SKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGP 210
Query: 1713 GAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGP 1772
+ + P G A GG S P L + S R L P P
Sbjct: 211 RQPSPGPTPPPFPGNR-----GTALGGGSIRQSP----LSSSSPFSNRP-----PLPPTP 256
Query: 1773 SGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASS 1832
S L D P P V G + A PP P +P VP P P+ASS
Sbjct: 257 SRALDDKPPPPPPPV-----GNRPSIHREAVPPPP-------PQNNKPPVPSTPRPSASS 304
Query: 1833 LPRKLLPWEEGPGPPPPPLPGPLAQPQASA 1862
+ P PPPP PGP P +S+
Sbjct: 305 --------QAPPPPPPPSRPGPPPLPPSSS 326
Score = 43.5 bits (101), Expect = 0.002
Identities = 73/275 (26%), Positives = 92/275 (33%), Gaps = 43/275 (15%)
Query: 1838 LPWEEGPGPPPPPLPGPLAQPQASALATVKA---SIISELSSK---------------LQ 1879
+P P PPPPP + + T +A +++S++S L
Sbjct: 1 MPVPPPPAPPPPPTFALANTEKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPILD 60
Query: 1880 QFGGSSAAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQRQRLSDDSQSSLLSKPVSS 1939
+ G+ A GG + GG GGG GG S+ L L L S
Sbjct: 61 KPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGPPGL--GGLFQAGMPKLRSTANRD 118
Query: 1940 LFQNWPKPPLPPLPTGTGVSPTAAAAPGATSPSASSSSTSTRHLQGVEFEMRPPLLRRAP 1999
+PPL P P G S + P S S H G P R P
Sbjct: 119 NDSGGSRPPLLP-PGGRSTSAKPFSPP---SGPGRFPVPSPGHRSGPP----EPQRNRMP 170
Query: 2000 SPSLLPASEHKVSPAPRPSSLPILPSGPLYPGLFDIRGSPTGGAGGSADPFAPVFVPPHP 2059
P S+ P P PS+ + S P RGSP GG P PP P
Sbjct: 171 PPRPDVGSKPDSIPPPVPSTPRPIQSSP------HNRGSPP-VPGGPRQPSPGPTPPPFP 223
Query: 2060 GISGGLGGALSGASRSLSPTRLLSLPPDKPFGAKP 2094
G G AL G S SP L PF +P
Sbjct: 224 ---GNRGTALGGGSIRQSP-----LSSSSPFSNRP 250
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 110 bits (275), Expect = 1e-23
Identities = 295/1224 (24%), Positives = 368/1224 (30%), Gaps = 244/1224 (19%)
Query: 936 PPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPL-P 994
P P + G P P G P PG GG A FD + ++G + + GP P
Sbjct: 155 PGTPGNPG--PPGPPGPPGPPGLGGNFAAQMAGGFDEKAG-GAQLGVMQGPMGPMGPRGP 211
Query: 995 PAHHHPPHHHHHHAPPPQPHHHHAH-------PPHPP----EMETGGSPDDPPPRLALGP 1043
P P P +P PP PP + G P R GP
Sbjct: 212 PGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGP 271
Query: 1044 QPSLRGWRGGGPSPTPGAPS-PSHHGSAG--GGGGSSQGPALRYFQLPPRAASAAMYVPA 1100
Q + RG+ G TPG P H G G G G + P ++ P + +
Sbjct: 272 QGA-RGFPG-----TPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGP 325
Query: 1101 RS---GRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPT 1157
R RGR GP + Q G PP P PA P AP K
Sbjct: 326 RGLPGERGRTGPAGAAGARGNDGQPGPAGPPGP--VGPAGG--PGFPGAPGAKGEA---- 377
Query: 1158 IIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSP-------APAMSPVPPS 1210
P+ + +QG E P P P G G G+ P AP ++ P
Sbjct: 378 ----GPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGF 433
Query: 1211 PSPVPTPASPSGPATLDFTSQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDED---- 1266
P P P L Q G + + E G + E AG+E
Sbjct: 434 PGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGA 493
Query: 1267 -GGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGAGSRAYGGGGG 1325
G GG+G PG R + G + + A G G A G G
Sbjct: 494 RGEPGGVGPIGPPGER---GAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGR 550
Query: 1326 SSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKESSEGGGAPQPPPRPPSPRY 1385
P P LTG+ D A P G K G P PP P+
Sbjct: 551 PGE-----PGLPGARGLTGRPGD-AGPQG----------KVGPSGAPGEDGRPGPPGPQG 594
Query: 1386 EAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAARRSLL 1445
P + G P A E G +AG EK LP +P L
Sbjct: 595 ARGQPG---------------VMGFPGPKGANGEPG-KAG----EKGLPGAPG------L 628
Query: 1446 HRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPRAPVT 1505
LP G PP P + AP L P P
Sbjct: 629 RGLPGKDGETG------AAGPPGPAGPAGERGEQGAPGPSGFQGL---------PGPP-- 671
Query: 1506 SGRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVE 1565
GPP E G P + P PR E G P P A + G
Sbjct: 672 ---GPPGEGGKPGDQGVPGEAGAPGLVGPRG--ERGFPGERGSPGAQGLQGPRG------ 720
Query: 1566 PLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLT 1625
P +P T GP PA P PP + P + A+ +
Sbjct: 721 -------------LPGTPGTDGPK----GASGPAGPPGAQGPPGLQGMPG--ERGAAGIA 761
Query: 1626 SYDSEVATLTQ-GASAAPGDPH------PPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEV 1678
+ + + G APG P GPP PA + GP P G+
Sbjct: 762 GPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAP 821
Query: 1679 DSRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFG 1738
R + P + + G G G G A GP+ G
Sbjct: 822 GERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ--------------G 867
Query: 1739 GSSTPGPPYPPQLMTPSKLRGR-----ALGASGGL-RPGPSGGLRDPVTPTSPTVSVTGA 1792
S PGP P + P RG A G G R GP G +P P P S
Sbjct: 868 PSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPS---- 923
Query: 1793 GTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGP----GPPP 1848
G DG R SGPP G AG P P PP K P ++GP GPP
Sbjct: 924 GKDGPKGARGDSGPP--GRAGEPGLQGPAGPP---------GEKGEPGDDGPSGAEGPPG 972
Query: 1849 PP----------LPGPLAQPQASALATVKASIISELSSKLQQFGGSSAAGGALPWARGGS 1898
P LPG + L + + G G P G +
Sbjct: 973 PQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGP-PGLTGPA 1031
Query: 1899 GGGGDSHHGGASYVPERTSSLQRQRLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGV 1958
G G GA P R + + D ++ + P + P PP P P G
Sbjct: 1032 GEPGREGSPGADGPPGRDGAAGVK--GDRGETGAVGAPGA------PGPPGSPGPAGPTG 1083
Query: 1959 SPTAAAAPGATSPSASSSSTSTRHLQGVE------FEMRPP------------LLRRAPS 2000
GA P S R +QG + E P L+ P
Sbjct: 1084 KQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPG 1143
Query: 2001 PSLLPASEHKVSPA----PRPSSLPILPS---------GPLYPGLFDIRGSPTGGAGGSA 2047
P + PA PR P+ PS GP+ P R TG AG
Sbjct: 1144 PPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPG 1203
Query: 2048 DPFAP-VFVPPHPGIS----GGLG 2066
+P P PP PGI GLG
Sbjct: 1204 NPGPPGPPGPPGPGIDMSAFAGLG 1227
Score = 87.4 bits (215), Expect = 1e-16
Identities = 268/1096 (24%), Positives = 331/1096 (30%), Gaps = 253/1096 (23%)
Query: 833 ISASESPG-PGGLASLGKHRPKGFFATESSFDPHHRAQPSYERPSFLPPGPGLMLRQKSI 891
+ + PG PG + G+ P G E + P R +P P PG
Sbjct: 359 VGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGP--RGEPG------TPGSPG------PA 404
Query: 892 GAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPVPSSSGRLTPSPRG 951
GA+ + P A + + + G+ P P PP P +T P+ P G
Sbjct: 405 GASGNPGTDGIPGAKGSAGAPGIAGAPGFPGP--RGPPGPQGATGPLGPKGQTGEPGIAG 462
Query: 952 GPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPL-PPAHHHPPHHHHH---- 1006
G G + P GP+ + + G+R + GP+ PP P +
Sbjct: 463 FKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEP-GGVGPIGPPGERGAPGNRGFPGQD 521
Query: 1007 --HAPPPQPHHHHAHPPHPPEMETG--GSPDDP--PPRLALGPQPSLRGWRGG-GPSPTP 1059
P P P+ G G P +P P L +P G +G GPS
Sbjct: 522 GLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPS--- 578
Query: 1060 GAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGE 1119
GAP G G+ P + F P A P ++ G KG L + G
Sbjct: 579 GAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGE----PGKA--GEKG-LPGAPGLRGL 631
Query: 1120 PQKGG--GLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSST 1177
P K G G P P PA + PS +P P P QG
Sbjct: 632 PGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGP----PGPPGEGGKPGDQGVPG 687
Query: 1178 EAEPPTQPEPTGGGGGGGSSPSP------APAMSPVPP---SPSPVPTPASPSG----PA 1224
EA P P G G G SP P P P P PA P G P
Sbjct: 688 EAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPG 747
Query: 1225 TLDFTSQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRH 1284
+ GAA + + + G E A +DGG G G PGP
Sbjct: 748 LQGMPGERGAAGIAGPKGDRGDVGEKGPEG-------APGKDGGRGLTGPIGPPGP---- 796
Query: 1285 SKSIDEGMFSAEPYLRLESAGSGAGYGGYG----AGSRAYGGGGGSSAFTSFLPPRPLVH 1340
AG+ G G AGS G G T PP P
Sbjct: 797 -------------------AGANGEKGEVGPPGPAGSAGARGAPGERGETG--PPGP--- 832
Query: 1341 PLTGKALDPASPLGLALAARERALKESSEGGGAPQPPPRPPSPRYEAPPPTPHHHSPHAH 1400
G A P + G A E+ E+ + G A P P+ PS PT
Sbjct: 833 --AGFAGPPGAD-GQPGAKGEQG--EAGQKGDAGAPGPQGPSGAPGPQGPT--------- 878
Query: 1401 HEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLL 1460
G + P AR G G + PP + + PP PG
Sbjct: 879 --------GVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNG---NPGPPGPPGPS---- 923
Query: 1461 QLGTEPPAPHPGVS-KPWRSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGP--- 1516
G + P G S P R+ P Q A +G P +DGP
Sbjct: 924 --GKDGPKGARGDSGPPGRAGEP--------------GLQGPAGPPGEKGEPGDDGPSGA 967
Query: 1517 -GVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSN 1575
G P P P E G P L P PS GE P + +
Sbjct: 968 EGPPGPQGLAGQRGIVGLPGQRGERGFPGL----PGPS-----GE--------PGKQGAP 1010
Query: 1576 SFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLT 1635
P PGP P P PA P A PP D A
Sbjct: 1011 GASGDRGP--PGPVGP-PGLTGPAGEPGREGSPG-ADGPPGRDGAAGVKGDRGE------ 1060
Query: 1636 QGASAAPGDPHPPGPPAPAAP---------APAAPQPGPDPPPGTDSGIEEVDSRSSSDH 1686
GA APG P PPG P PA P A A GP P G GI+
Sbjct: 1061 TGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGA-RGIQ---------- 1109
Query: 1687 PLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPP 1746
G G G G G L + + G PGPP
Sbjct: 1110 -------------------GPQGPRGDKGEAGEPGERGLKGHRGFT-----GLQGLPGPP 1145
Query: 1747 YPPQLMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGP 1806
P G G P G R P P P +G DG + GP
Sbjct: 1146 GPS-------------GDQGASGPAGPSGPRGPPGPVGP------SGKDGANGIPGPIGP 1186
Query: 1807 P----------TAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGP----PPPPLP 1852
P AG G P P PP P S+ L P E+GP P
Sbjct: 1187 PGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAF-AGLGPREKGPDPLQYMRADQAA 1245
Query: 1853 GPLAQPQASALATVKA 1868
G L Q A AT+K+
Sbjct: 1246 GGLRQHDAEVDATLKS 1261
Score = 68.9 bits (167), Expect = 5e-11
Identities = 182/733 (24%), Positives = 216/733 (29%), Gaps = 161/733 (21%)
Query: 1360 RERALKESSEGGGAPQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRE 1419
R R + + G P PP PP P P ++ G +
Sbjct: 149 RGRDGEPGTPGNPGPPGPPGPPGP-------------PGLGGNFAAQMAGGFDEKAGGAQ 195
Query: 1420 LGYRAGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRS 1479
LG G P P R P A GP Q G PGVS P
Sbjct: 196 LGVMQG--------PMGPMGPRGP-----PGPAGAPGPQGFQ-GNPGEPGEPGVSGPMGP 241
Query: 1480 AAPEEPERLPLHVRFLENCQPRAPVTSGR-GPPSEDGP-GVPPPSPRRSVPPSPTSPRAS 1537
P P P P G G P + G G P P R P +P P
Sbjct: 242 RGPPGP--------------PGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVK 287
Query: 1538 EENGLPLL---VLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGP--PHPL 1592
G P L AP V E G P +PGP P L
Sbjct: 288 GHRGYPGLDGAKGEAGAPGVKGESG-------------------SPGENGSPGPMGPRGL 328
Query: 1593 P------------------DTPAPATPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATL 1634
P P PA P PV P A P + A
Sbjct: 329 PGERGRTGPAGAAGARGNDGQPGPAGPPGPVGP----AGGPGFPGAPGAKGEAGPTGARG 384
Query: 1635 TQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSA 1694
+GA G+P PG P PA A+ PG D PG SA
Sbjct: 385 PEGAQGPRGEPGTPGSPGPAG---ASGNPGTDGIPGAK-------------------GSA 422
Query: 1695 STLSSLSAEG-GGSAGGGGGAGAGVASGP--ELLDTYVAYLDGQAFGGSSTPGPPYPPQL 1751
A G G G G GA GP + + +A G+ G PGP P
Sbjct: 423 GAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQ-GPKGEPGPAGPQGA 481
Query: 1752 MTPSKLRGR--ALGASGGLRP-GPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPT 1808
P+ G+ A G GG+ P GP G P P G DGL + G
Sbjct: 482 PGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFP-------GQDGLAGPKGAPGERG 534
Query: 1809 AGVAGGPVAV--EPEVPPVP-LPTASSLPRKLLPWEEGP----GPPPPPLPGPLAQPQAS 1861
GP +P P P LP A L + P + GP GP P P
Sbjct: 535 PSGLAGPKGANGDPGRPGEPGLPGARGLTGR--PGDAGPQGKVGPSGAPGEDGRPGPPGP 592
Query: 1862 ALATVKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQR 1921
A + ++ K A LP A G G G GA+ P
Sbjct: 593 QGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPA-- 650
Query: 1922 QRLSDDSQSSLLSKPVSSLFQNWPKPPLPP----LPTGTGVSPTAAAAPGATSPSASSSS 1977
+ P S FQ P PP PP P GV P A APG P
Sbjct: 651 ------GERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGV-PGEAGAPGLVGPRGERGF 703
Query: 1978 TSTRHLQGVEFEMRPPLLRRAPSPSLLPASEHKVSPAPRPSSLPILPSGPLYPGLFDIRG 2037
R G + P L P + P+ +S P P G P ++G
Sbjct: 704 PGERGSPGAQGLQGPRGLPGTPG-----------TDGPKGASGPAGPPGAQGPP--GLQG 750
Query: 2038 SP-TGGAGGSADP 2049
P GA G A P
Sbjct: 751 MPGERGAAGIAGP 763
Score = 66.2 bits (160), Expect = 3e-10
Identities = 168/648 (25%), Positives = 199/648 (30%), Gaps = 125/648 (19%)
Query: 1509 GPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLP 1568
GP DG P +P PP P P GL A D + G
Sbjct: 147 GPRGRDGEPGTPGNPGPPGPPGPPGP-----PGLGGNFAAQMAGGFDEKAGGAQL----- 196
Query: 1569 PPLEFSNSFEKPESPLTP-GPPHPL--------------PDTPAPATPLPPVPPPAVAAA 1613
+ P P+ P GPP P P P + P+ P PP
Sbjct: 197 ------GVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGK 250
Query: 1614 PPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDS 1673
P D A QGA PG P PG PG D G ++
Sbjct: 251 PGD-DGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRG------YPGLDGAKG-EA 302
Query: 1674 GIEEVDSRSSSDHPLETISSASTLSSLSAEG-GGSAGGGGGAGAGVASGPELLDTYVAYL 1732
G V S S P E S + G G G G AGA A G
Sbjct: 303 GAPGVKGESGS--PGENGSP----GPMGPRGLPGERGRTGPAGAAGARGN---------- 346
Query: 1733 DGQAFGGSSTPGPPYPPQLMTPSKLRG--RALGASGGLRP-------GPSGGLRDPVTPT 1783
DGQ PGP PP + P+ G A GA G P G G +P TP
Sbjct: 347 DGQ-------PGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPG 399
Query: 1784 SP-TVSVTG-AGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWE 1841
SP +G GTDG+ + +G P G+AG P P PP P L K E
Sbjct: 400 SPGPAGASGNPGTDGIPGAKGSAGAP--GIAGAPGFPGPRGPPGPQGATGPLGPKGQTGE 457
Query: 1842 EG-------------PGPP-PPPLPGPLAQPQASALATVKASIISELSSKLQQ------- 1880
G PGP P PGP A + A + + + ++
Sbjct: 458 PGIAGFKGEQGPKGEPGPAGPQGAPGP-AGEEGKRGARGEPGGVGPIGPPGERGAPGNRG 516
Query: 1881 FGGSSAAGG--ALPWARGGSGGGGDSHHGGASYVPERTSSLQRQRLSD-DSQSSLLSKPV 1937
F G G P RG SG G G P + L+ + K
Sbjct: 517 FPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVG 576
Query: 1938 SSLFQNWPKPPLPPLPTGTGVSPTAAAAPGATSPSASSSSTSTRHLQGVEFEMRPPLLRR 1997
S P PP P G P PG + + L G P LR
Sbjct: 577 PSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGA------PGLRG 630
Query: 1998 APSPS-----------LLPASEHKVSPAPRPSSLPILPSGPLYPGLFDIRGSPTGGAGGS 2046
P PA E AP PS LP P PG G G G
Sbjct: 631 LPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPG----EGGKPGDQGVP 686
Query: 2047 ADPFAPVFVPPHPGISGGLGGALSGASRSLSPTRLLSLPP--DKPFGA 2092
+ AP V P G G G S ++ L R L P D P GA
Sbjct: 687 GEAGAPGLVGPR-GERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGA 733
Score = 57.0 bits (136), Expect = 2e-07
Identities = 115/501 (22%), Positives = 143/501 (28%), Gaps = 129/501 (25%)
Query: 1570 PLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLTSYDS 1629
P + + + +P G P + D P P P P P D
Sbjct: 90 PTDLATASGQPGPKGQKGEPGDIKDIVGPKGP--PGPQGPAGEQGPRGDRGDKG-----E 142
Query: 1630 EVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHPLE 1689
+ A +G PG P PGPP P PGP PPG
Sbjct: 143 KGAPGPRGRDGEPGTPGNPGPPGP---------PGPPGPPGLGGNF-------------- 179
Query: 1690 TISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPP 1749
+ GG GGA GV GP G GPP P
Sbjct: 180 ----------AAQMAGGFDEKAGGAQLGVMQGP--------------MGPMGPRGPPGP- 214
Query: 1750 QLMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPP-- 1807
GA PGP G +P P P G G + R GPP
Sbjct: 215 ------------AGA-----PGPQGFQGNPGEPGEP-------GVSGPMGPRGPPGPPGK 250
Query: 1808 --TAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLAQPQASALAT 1865
G AG P PP P P P LPG L
Sbjct: 251 PGDDGEAGKPGKAGERGPPGPQGARGF-------------PGTPGLPGVKGHRGYPGL-- 295
Query: 1866 VKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQRQRLS 1925
G+ GA P +G SG G+ +G + R +R R
Sbjct: 296 ----------------DGAKGEAGA-PGVKGESGSPGE--NGSPGPMGPRGLPGERGRTG 336
Query: 1926 DDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGVSPTAAAAPGATSPSASSSSTSTRHLQG 1985
+ P P PP P G P APGA + + + QG
Sbjct: 337 PAGAAGARGN------DGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQG 390
Query: 1986 VEFEMRPPLLRRAPSPSLLPASEHKVSPAPRPSSLPILPSGPLYPGLFDIRGSPTGGAGG 2045
E P S P ++ + A + P + P +PG RG P G G
Sbjct: 391 PRGEPGTPGSPGPAGASGNPGTD-GIPGAKGSAGAPGIAGAPGFPG---PRGPP--GPQG 444
Query: 2046 SADPFAPVFVPPHPGISGGLG 2066
+ P P PGI+G G
Sbjct: 445 ATGPLGPKGQTGEPGIAGFKG 465
Score = 53.1 bits (126), Expect = 3e-06
Identities = 48/171 (28%), Positives = 62/171 (36%), Gaps = 25/171 (14%)
Query: 409 PFQESPKYAARRRGPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGS 468
P + P A +GP TG+T P A PGAA P ++G+
Sbjct: 863 PGPQGPSGAPGPQGP--TGVTGPKGARGAQGPPGAT-------GFPGAAGRVGPPGSNGN 913
Query: 469 QGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPREGPA 528
G P P+ K P+GAR S GR E + P G P G P +
Sbjct: 914 PGPPGPPGPSGK---------DGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGP 964
Query: 529 GGTGGSGGPGGSLGSRG-------RRRKLYSAVPGRSFMAVKSYQAQAEGE 572
G G GP G G RG R + + +PG S K A G+
Sbjct: 965 SGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGD 1015
Score = 46.6 bits (109), Expect = 3e-04
Identities = 35/94 (37%), Positives = 43/94 (45%), Gaps = 22/94 (23%)
Query: 454 PGAASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQP 513
PG A G PGP + G P AP K +G P GAR ++G P
Sbjct: 350 PGPA--GPPGPVGPAGGPGFPGAPGAKGEAG-------PTGARGPEGAQG---------P 391
Query: 514 RGRPSSSGTPREGPAGGTGGSGGPG--GSLGSRG 545
RG P + G+P GPAG +G G G G+ GS G
Sbjct: 392 RGEPGTPGSP--GPAGASGNPGTDGIPGAKGSAG 423
Score = 45.1 bits (105), Expect = 8e-04
Identities = 48/144 (33%), Positives = 55/144 (38%), Gaps = 20/144 (13%)
Query: 418 ARRRGPPGT-GLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQSQPSA 476
A +G PG GL P + +T A P A GAPGP SG QG P
Sbjct: 617 AGEKGLPGAPGLRGLPG---KDGETGAAGPPGPAGPAGERGEQGAPGP-SGFQGLPGPPG 672
Query: 477 PTTKLSS----GTLRSASSP-----RGARARSPSRGRHPEDAKRQPRGRPSSSGTP---- 523
P + G A +P RG R RG + PRG P + GT
Sbjct: 673 PPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKG 732
Query: 524 REGPAGGTGGSGGPG--GSLGSRG 545
GPAG G G PG G G RG
Sbjct: 733 ASGPAGPPGAQGPPGLQGMPGERG 756
Score = 42.7 bits (99), Expect = 0.004
Identities = 42/135 (31%), Positives = 55/135 (40%), Gaps = 26/135 (19%)
Query: 414 PKYAARRRGPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGA-ASSGAPGPTSGSQGQS 472
P+ A RG PGT + PA N T PGA S+GAPG +G+ G
Sbjct: 385 PEGAQGPRGEPGTPGSPGPAGASGNPGTD---------GIPGAKGSAGAPG-IAGAPGFP 434
Query: 473 QPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPREGPAGGTG 532
P P + A+ P G + ++ G ++ P+G P GPAG G
Sbjct: 435 GPRGPPGP------QGATGPLGPKGQTGEPGIAGFKGEQGPKGEP--------GPAGPQG 480
Query: 533 GSGGPGGSLGSRGRR 547
G P G G RG R
Sbjct: 481 APG-PAGEEGKRGAR 494
Score = 42.7 bits (99), Expect = 0.004
Identities = 31/97 (31%), Positives = 39/97 (40%), Gaps = 10/97 (10%)
Query: 460 GAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSS 519
G PG T G +G S P+ P L+ RGA + +G + ++ P G P
Sbjct: 723 GTPG-TDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGK 781
Query: 520 SG-------TPREGPAGGTGGSG--GPGGSLGSRGRR 547
G GPAG G G GP G GS G R
Sbjct: 782 DGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGAR 818
Score = 42.7 bits (99), Expect = 0.004
Identities = 32/101 (31%), Positives = 40/101 (39%), Gaps = 10/101 (9%)
Query: 453 APGAASS-GAPGPTS-----GSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHP 506
APGA G+PGP G +G++ P R P+G R G
Sbjct: 1066 APGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPG 1125
Query: 507 EDAKRQPRGRPSSSGTPREGPAGGTG--GSGGPGGSLGSRG 545
E + RG G P GP G +G G+ GP G G RG
Sbjct: 1126 ERGLKGHRGFTGLQGLP--GPPGPSGDQGASGPAGPSGPRG 1164
Score = 40.8 bits (94), Expect = 0.015
Identities = 51/172 (29%), Positives = 66/172 (38%), Gaps = 26/172 (15%)
Query: 411 QESPKYAARRRGPPG-TGLTVPPALLRANSDTSMALPDWMVFSA-----PGA-ASSGAPG 463
++ P+ A + G G TG PP AN + P SA PG +G PG
Sbjct: 772 EKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPG 831
Query: 464 PT--SGSQG-QSQPSAPTTKLSSGTLRSASSP-----RGARARSPSRGRHPEDAKRQPRG 515
P +G G QP A + +G A +P GA G R +G
Sbjct: 832 PAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQG 891
Query: 516 RPSSSGTP----REGPAGGTGGSG-----GPGGSLGSRGRRRKLYSAVPGRS 558
P ++G P R GP G G G GP G G +G R S PGR+
Sbjct: 892 PPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGD--SGPPGRA 941
Score = 38.1 bits (87), Expect = 0.094
Identities = 36/140 (25%), Positives = 48/140 (34%), Gaps = 6/140 (4%)
Query: 409 PFQESPKYAARRRGPPGTGLTVPPALLRANSD---TSMALPDWMVFSAPGAASSGAPGPT 465
P + PK A+ GPPG PP L + +A P GAPG
Sbjct: 725 PGTDGPKGASGPAGPPGA--QGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGK- 781
Query: 466 SGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPRE 525
G +G + P P + + P G + +RG E + P G +G P
Sbjct: 782 DGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGA 841
Query: 526 GPAGGTGGSGGPGGSLGSRG 545
G G G G G G
Sbjct: 842 DGQPGAKGEQGEAGQKGDAG 861
Score = 37.4 bits (85), Expect = 0.16
Identities = 30/94 (31%), Positives = 35/94 (37%), Gaps = 16/94 (17%)
Query: 454 PGAASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQP 513
PG A GAPGP +P P S P G R G+ +D +
Sbjct: 212 PGPA--GAPGPQGFQGNPGEPGEP----------GVSGPMGPRGPPGPPGKPGDDGEAGK 259
Query: 514 RGRPSSSGTPREGPAGGTGGSGGPG--GSLGSRG 545
G+ G P GP G G G PG G G RG
Sbjct: 260 PGKAGERGPP--GPQGARGFPGTPGLPGVKGHRG 291
Score = 37.4 bits (85), Expect = 0.16
Identities = 41/137 (29%), Positives = 52/137 (37%), Gaps = 24/137 (17%)
Query: 421 RGPPGT-GLTVPPALLRANSDTSMA--LPDWMVFSAPGAAS-SGAPGPTS-----GSQGQ 471
RGPPG G T P + +A + PG A GAPGP G++G+
Sbjct: 437 RGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGE 496
Query: 472 SQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSG-TPREGPAGG 530
P P G R +RG +D P+G P G + GP G
Sbjct: 497 PGGVGPI------------GPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGA 544
Query: 531 TGGSGGPG--GSLGSRG 545
G G PG G G+RG
Sbjct: 545 NGDPGRPGEPGLPGARG 561
Score = 37.0 bits (84), Expect = 0.21
Identities = 28/84 (33%), Positives = 33/84 (39%), Gaps = 4/84 (4%)
Query: 456 AASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRG 515
A +SG PGP G +G+ P + P G + RG E PRG
Sbjct: 94 ATASGQPGP-KGQKGE--PGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRG 150
Query: 516 RPSSSGTP-REGPAGGTGGSGGPG 538
R GTP GP G G G PG
Sbjct: 151 RDGEPGTPGNPGPPGPPGPPGPPG 174
Score = 37.0 bits (84), Expect = 0.21
Identities = 34/104 (32%), Positives = 42/104 (40%), Gaps = 15/104 (14%)
Query: 453 APGAASS-GAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKR 511
APGA+ G PGP G G + P+ + S A P G + +G E
Sbjct: 1009 APGASGDRGPPGPV-GPPGLTGPAGEPGREGSP---GADGPPGRDGAAGVKGDRGETGAV 1064
Query: 512 QPRGRPSSSGTPREGPAGGTG--------GSGGPGGSLGSRGRR 547
G P G+P GPAG TG G+ GP G G G R
Sbjct: 1065 GAPGAPGPPGSP--GPAGPTGKQGDRGEAGAQGPMGPSGPAGAR 1106
Score = 36.6 bits (83), Expect = 0.27
Identities = 45/140 (32%), Positives = 53/140 (37%), Gaps = 30/140 (21%)
Query: 418 ARRRGPPGT----GLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPT--SGSQGQ 471
A RGPPG G P L D A G A GAPG SGS G+
Sbjct: 263 AGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLD----GAKGEA--GAPGVKGESGSPGE 316
Query: 472 SQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPRE-GPAGG 530
+ P R + P GA + +RG G+P +G P GPAGG
Sbjct: 317 NGSPGPMGPRGLPGERGRTGPAGA---AGARGND---------GQPGPAGPPGPVGPAGG 364
Query: 531 TGGSGGPG-----GSLGSRG 545
G G PG G G+RG
Sbjct: 365 PGFPGAPGAKGEAGPTGARG 384
Score = 36.6 bits (83), Expect = 0.27
Identities = 42/142 (29%), Positives = 50/142 (35%), Gaps = 19/142 (13%)
Query: 414 PKYAARRRGPPGTGLTVPPALLRANSDTSM----ALPDWMVFSA-PG-AASSGAPGPTS- 466
PK A RGP +GL P AN D LP + PG A G GP+
Sbjct: 526 PKGAPGERGP--SGLAGPKG---ANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGA 580
Query: 467 -GSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPRE 525
G G+ P P + P+GA G K P G P G P +
Sbjct: 581 PGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGE-----KGLP-GAPGLRGLPGK 634
Query: 526 GPAGGTGGSGGPGGSLGSRGRR 547
G G GP G G RG +
Sbjct: 635 DGETGAAGPPGPAGPAGERGEQ 656
Score = 36.6 bits (83), Expect = 0.27
Identities = 39/144 (27%), Positives = 47/144 (32%), Gaps = 12/144 (8%)
Query: 414 PKYAARRRGPPGT-------GLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTS 466
PK A +GPPG G PP P SG PG
Sbjct: 883 PKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAG 942
Query: 467 --GSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRG---RPSSSG 521
G QG + P + A P G + + RG +R RG P SG
Sbjct: 943 EPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSG 1002
Query: 522 TPREGPAGGTGGSGGPGGSLGSRG 545
P + A G G GP G +G G
Sbjct: 1003 EPGKQGAPGASGDRGPPGPVGPPG 1026
Score = 36.2 bits (82), Expect = 0.36
Identities = 39/127 (30%), Positives = 43/127 (33%), Gaps = 15/127 (11%)
Query: 422 GPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQSQPSAPTTKL 481
GPPG P L N MA A GA GP G G P P
Sbjct: 162 GPPGPPGPPGPPGLGGNFAAQMA--GGFDEKAGGAQLGVMQGPM-GPMGPRGPPGPA--- 215
Query: 482 SSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTP-REGPAG--GTGGSGGPG 538
A P+G + G PRG P G P +G AG G G GP
Sbjct: 216 ------GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPP 269
Query: 539 GSLGSRG 545
G G+RG
Sbjct: 270 GPQGARG 276
Score = 35.8 bits (81), Expect = 0.47
Identities = 28/86 (32%), Positives = 32/86 (37%), Gaps = 13/86 (15%)
Query: 460 GAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSS 519
G PGP SG QG S P+ P S PRG G+ + P G P
Sbjct: 1143 GPPGP-SGDQGASGPAGP------------SGPRGPPGPVGPSGKDGANGIPGPIGPPGP 1189
Query: 520 SGTPREGPAGGTGGSGGPGGSLGSRG 545
G E G G+ GP G G G
Sbjct: 1190 RGRSGETGPAGPPGNPGPPGPPGPPG 1215
Score = 34.7 bits (78), Expect = 1.0
Identities = 35/128 (27%), Positives = 43/128 (33%), Gaps = 27/128 (21%)
Query: 421 RGPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQSQPSAPTTK 480
RGPPG PP + D P A G PGP P P K
Sbjct: 242 RGPPG-----PPG--KPGDDGEAGKPG-------KAGERGPPGPQGARGFPGTPGLPGVK 287
Query: 481 LSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPRE-GPAG--GTGGSGGP 537
RG ++G + G P +G+P GP G G G GP
Sbjct: 288 ----------GHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGP 337
Query: 538 GGSLGSRG 545
G+ G+RG
Sbjct: 338 AGAAGARG 345
Score = 34.3 bits (77), Expect = 1.4
Identities = 26/92 (28%), Positives = 33/92 (35%), Gaps = 2/92 (2%)
Query: 460 GAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPS--RGRHPEDAKRQPRGRP 517
G+PGP S P K S+G A +P R P +G + G P
Sbjct: 399 GSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEP 458
Query: 518 SSSGTPREGPAGGTGGSGGPGGSLGSRGRRRK 549
+G E G G GP G+ G G K
Sbjct: 459 GIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGK 490
Score = 33.5 bits (75), Expect = 2.3
Identities = 27/82 (32%), Positives = 33/82 (40%), Gaps = 14/82 (17%)
Query: 454 PG-AASSGAPGPT--SGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAK 510
PG + GA GP SG +G P P+ K + + P G R RS G
Sbjct: 1145 PGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETG------- 1197
Query: 511 RQPRGRPSSSGTPREGPAGGTG 532
P G P + G P GP G G
Sbjct: 1198 --PAGPPGNPGPP--GPPGPPG 1215
Score = 33.1 bits (74), Expect = 3.0
Identities = 44/147 (29%), Positives = 53/147 (36%), Gaps = 19/147 (12%)
Query: 409 PFQESPKYAARRRGPPGT-GLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSG 467
P P+ G PG G PP A P M F P A+ G PG +G
Sbjct: 566 PGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ-----PGVMGFPGPKGAN-GEPGK-AG 618
Query: 468 SQGQSQPSAPTTKLSSGT--LRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPRE 525
+G P AP + G A+ P G + RG +G P G P E
Sbjct: 619 EKGL--PGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGE 676
Query: 526 GPAGGTGGSGGPG-----GSLGSRGRR 547
G G G G PG G +G RG R
Sbjct: 677 G--GKPGDQGVPGEAGAPGLVGPRGER 701
Score = 32.7 bits (73), Expect = 4.0
Identities = 27/88 (30%), Positives = 32/88 (36%), Gaps = 8/88 (9%)
Query: 460 GAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSP--RGARARSPSRGRHPEDAKRQPRGRP 517
GAPG SG +G P P G A P G+ GR + RG
Sbjct: 1008 GAPG-ASGDRGPPGPVGPP-----GLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGET 1061
Query: 518 SSSGTPREGPAGGTGGSGGPGGSLGSRG 545
+ G P G+ G GP G G RG
Sbjct: 1062 GAVGAPGAPGPPGSPGPAGPTGKQGDRG 1089
Score = 32.3 bits (72), Expect = 5.2
Identities = 33/135 (24%), Positives = 40/135 (29%), Gaps = 18/135 (13%)
Query: 421 RGPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQSQPSAPTTK 480
RGPPG P + N PG + P G G+ K
Sbjct: 209 RGPPGPAGAPGPQGFQGNPGEP---------GEPGVSGPMGPRGPPGPPGKPGDDGEAGK 259
Query: 481 LSSGTLRSASSPRGARARSPS---------RGRHPEDAKRQPRGRPSSSGTPREGPAGGT 531
R P+GAR + RG D + G P G G+
Sbjct: 260 PGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGS 319
Query: 532 GGSGGPGGSLGSRGR 546
G GP G G RGR
Sbjct: 320 PGPMGPRGLPGERGR 334
Score = 32.0 bits (71), Expect = 6.8
Identities = 26/87 (29%), Positives = 31/87 (35%), Gaps = 10/87 (11%)
Query: 464 PTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTP 523
PT + QP K G ++ P+G G E R RG G P
Sbjct: 90 PTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAG---EQGPRGDRGDKGEKGAP 146
Query: 524 REGPAG-----GTGGSGGPGGSLGSRG 545
GP G GT G+ GP G G G
Sbjct: 147 --GPRGRDGEPGTPGNPGPPGPPGPPG 171
Score = 31.6 bits (70), Expect = 8.8
Identities = 35/133 (26%), Positives = 41/133 (30%), Gaps = 21/133 (15%)
Query: 422 GPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASS-GAPGPTS--GSQGQSQPSAPT 478
GPPG P R +S PG A G GP G +G+ P+
Sbjct: 918 GPPGPSGKDGPKGARGDS------------GPPGRAGEPGLQGPAGPPGEKGEPGDDGPS 965
Query: 479 TKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTP----REGPAGGTGGS 534
+ + RG RG P G P G P GP G G
Sbjct: 966 GAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPP 1025
Query: 535 G--GPGGSLGSRG 545
G GP G G G
Sbjct: 1026 GLTGPAGEPGREG 1038
Score = 31.6 bits (70), Expect = 8.8
Identities = 40/149 (26%), Positives = 53/149 (35%), Gaps = 29/149 (19%)
Query: 409 PFQESPKYAARRRGPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGP---- 464
P ++ A+ RGPPG PP L + +PGA G PG
Sbjct: 1004 PGKQGAPGASGDRGPPGP--VGPPGLTGPAGEPGRE-------GSPGA--DGPPGRDGAA 1052
Query: 465 -TSGSQGQS----QPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSS 519
G +G++ P AP S G P G + RG P G +
Sbjct: 1053 GVKGDRGETGAVGAPGAPGPPGSPG-------PAGPTGKQGDRGEAGAQGPMGPSGPAGA 1105
Query: 520 SGTPR-EGPAGGTGGSGGPGGSLGSRGRR 547
G +GP G G +G PG G +G R
Sbjct: 1106 RGIQGPQGPRGDKGEAGEPG-ERGLKGHR 1133
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 110 bits (275), Expect = 1e-23
Identities = 295/1224 (24%), Positives = 368/1224 (30%), Gaps = 244/1224 (19%)
Query: 936 PPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPL-P 994
P P + G P P G P PG GG A FD + ++G + + GP P
Sbjct: 86 PGTPGNPG--PPGPPGPPGPPGLGGNFAAQMAGGFDEKAG-GAQLGVMQGPMGPMGPRGP 142
Query: 995 PAHHHPPHHHHHHAPPPQPHHHHAH-------PPHPP----EMETGGSPDDPPPRLALGP 1043
P P P +P PP PP + G P R GP
Sbjct: 143 PGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGP 202
Query: 1044 QPSLRGWRGGGPSPTPGAPS-PSHHGSAG--GGGGSSQGPALRYFQLPPRAASAAMYVPA 1100
Q + RG+ G TPG P H G G G G + P ++ P + +
Sbjct: 203 QGA-RGFPG-----TPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGP 256
Query: 1101 RS---GRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPT 1157
R RGR GP + Q G PP P PA P AP K
Sbjct: 257 RGLPGERGRTGPAGAAGARGNDGQPGPAGPPGP--VGPAGG--PGFPGAPGAKGEA---- 308
Query: 1158 IIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSP-------APAMSPVPPS 1210
P+ + +QG E P P P G G G+ P AP ++ P
Sbjct: 309 ----GPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGF 364
Query: 1211 PSPVPTPASPSGPATLDFTSQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDED---- 1266
P P P L Q G + + E G + E AG+E
Sbjct: 365 PGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGA 424
Query: 1267 -GGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGAGSRAYGGGGG 1325
G GG+G PG R + G + + A G G A G G
Sbjct: 425 RGEPGGVGPIGPPGER---GAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGR 481
Query: 1326 SSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKESSEGGGAPQPPPRPPSPRY 1385
P P LTG+ D A P G K G P PP P+
Sbjct: 482 PGE-----PGLPGARGLTGRPGD-AGPQG----------KVGPSGAPGEDGRPGPPGPQG 525
Query: 1386 EAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAARRSLL 1445
P + G P A E G +AG EK LP +P L
Sbjct: 526 ARGQPG---------------VMGFPGPKGANGEPG-KAG----EKGLPGAPG------L 559
Query: 1446 HRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPRAPVT 1505
LP G PP P + AP L P P
Sbjct: 560 RGLPGKDGETG------AAGPPGPAGPAGERGEQGAPGPSGFQGL---------PGPP-- 602
Query: 1506 SGRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVE 1565
GPP E G P + P PR E G P P A + G
Sbjct: 603 ---GPPGEGGKPGDQGVPGEAGAPGLVGPRG--ERGFPGERGSPGAQGLQGPRG------ 651
Query: 1566 PLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLT 1625
P +P T GP PA P PP + P + A+ +
Sbjct: 652 -------------LPGTPGTDGPK----GASGPAGPPGAQGPPGLQGMPG--ERGAAGIA 692
Query: 1626 SYDSEVATLTQ-GASAAPGDPH------PPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEV 1678
+ + + G APG P GPP PA + GP P G+
Sbjct: 693 GPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAP 752
Query: 1679 DSRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFG 1738
R + P + + G G G G A GP+ G
Sbjct: 753 GERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ--------------G 798
Query: 1739 GSSTPGPPYPPQLMTPSKLRGR-----ALGASGGL-RPGPSGGLRDPVTPTSPTVSVTGA 1792
S PGP P + P RG A G G R GP G +P P P S
Sbjct: 799 PSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPS---- 854
Query: 1793 GTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGP----GPPP 1848
G DG R SGPP G AG P P PP K P ++GP GPP
Sbjct: 855 GKDGPKGARGDSGPP--GRAGEPGLQGPAGPP---------GEKGEPGDDGPSGAEGPPG 903
Query: 1849 PP----------LPGPLAQPQASALATVKASIISELSSKLQQFGGSSAAGGALPWARGGS 1898
P LPG + L + + G G P G +
Sbjct: 904 PQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGP-PGLTGPA 962
Query: 1899 GGGGDSHHGGASYVPERTSSLQRQRLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGV 1958
G G GA P R + + D ++ + P + P PP P P G
Sbjct: 963 GEPGREGSPGADGPPGRDGAAGVK--GDRGETGAVGAPGA------PGPPGSPGPAGPTG 1014
Query: 1959 SPTAAAAPGATSPSASSSSTSTRHLQGVE------FEMRPP------------LLRRAPS 2000
GA P S R +QG + E P L+ P
Sbjct: 1015 KQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPG 1074
Query: 2001 PSLLPASEHKVSPA----PRPSSLPILPS---------GPLYPGLFDIRGSPTGGAGGSA 2047
P + PA PR P+ PS GP+ P R TG AG
Sbjct: 1075 PPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPG 1134
Query: 2048 DPFAP-VFVPPHPGIS----GGLG 2066
+P P PP PGI GLG
Sbjct: 1135 NPGPPGPPGPPGPGIDMSAFAGLG 1158
Score = 87.4 bits (215), Expect = 1e-16
Identities = 268/1096 (24%), Positives = 331/1096 (30%), Gaps = 253/1096 (23%)
Query: 833 ISASESPG-PGGLASLGKHRPKGFFATESSFDPHHRAQPSYERPSFLPPGPGLMLRQKSI 891
+ + PG PG + G+ P G E + P R +P P PG
Sbjct: 290 VGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGP--RGEPG------TPGSPG------PA 335
Query: 892 GAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPVPSSSGRLTPSPRG 951
GA+ + P A + + + G+ P P PP P +T P+ P G
Sbjct: 336 GASGNPGTDGIPGAKGSAGAPGIAGAPGFPGP--RGPPGPQGATGPLGPKGQTGEPGIAG 393
Query: 952 GPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPL-PPAHHHPPHHHHH---- 1006
G G + P GP+ + + G+R + GP+ PP P +
Sbjct: 394 FKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEP-GGVGPIGPPGERGAPGNRGFPGQD 452
Query: 1007 --HAPPPQPHHHHAHPPHPPEMETG--GSPDDP--PPRLALGPQPSLRGWRGG-GPSPTP 1059
P P P+ G G P +P P L +P G +G GPS
Sbjct: 453 GLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPS--- 509
Query: 1060 GAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGE 1119
GAP G G+ P + F P A P ++ G KG L + G
Sbjct: 510 GAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGE----PGKA--GEKG-LPGAPGLRGL 562
Query: 1120 PQKGG--GLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSST 1177
P K G G P P PA + PS +P P P QG
Sbjct: 563 PGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGP----PGPPGEGGKPGDQGVPG 618
Query: 1178 EAEPPTQPEPTGGGGGGGSSPSP------APAMSPVPP---SPSPVPTPASPSG----PA 1224
EA P P G G G SP P P P P PA P G P
Sbjct: 619 EAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPG 678
Query: 1225 TLDFTSQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRH 1284
+ GAA + + + G E A +DGG G G PGP
Sbjct: 679 LQGMPGERGAAGIAGPKGDRGDVGEKGPEG-------APGKDGGRGLTGPIGPPGP---- 727
Query: 1285 SKSIDEGMFSAEPYLRLESAGSGAGYGGYG----AGSRAYGGGGGSSAFTSFLPPRPLVH 1340
AG+ G G AGS G G T PP P
Sbjct: 728 -------------------AGANGEKGEVGPPGPAGSAGARGAPGERGETG--PPGP--- 763
Query: 1341 PLTGKALDPASPLGLALAARERALKESSEGGGAPQPPPRPPSPRYEAPPPTPHHHSPHAH 1400
G A P + G A E+ E+ + G A P P+ PS PT
Sbjct: 764 --AGFAGPPGAD-GQPGAKGEQG--EAGQKGDAGAPGPQGPSGAPGPQGPT--------- 809
Query: 1401 HEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLL 1460
G + P AR G G + PP + + PP PG
Sbjct: 810 --------GVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNG---NPGPPGPPGPS---- 854
Query: 1461 QLGTEPPAPHPGVS-KPWRSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGP--- 1516
G + P G S P R+ P Q A +G P +DGP
Sbjct: 855 --GKDGPKGARGDSGPPGRAGEP--------------GLQGPAGPPGEKGEPGDDGPSGA 898
Query: 1517 -GVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSN 1575
G P P P E G P L P PS GE P + +
Sbjct: 899 EGPPGPQGLAGQRGIVGLPGQRGERGFPGL----PGPS-----GE--------PGKQGAP 941
Query: 1576 SFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLT 1635
P PGP P P PA P A PP D A
Sbjct: 942 GASGDRGP--PGPVGP-PGLTGPAGEPGREGSPG-ADGPPGRDGAAGVKGDRGE------ 991
Query: 1636 QGASAAPGDPHPPGPPAPAAP---------APAAPQPGPDPPPGTDSGIEEVDSRSSSDH 1686
GA APG P PPG P PA P A A GP P G GI+
Sbjct: 992 TGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGA-RGIQ---------- 1040
Query: 1687 PLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPP 1746
G G G G G L + + G PGPP
Sbjct: 1041 -------------------GPQGPRGDKGEAGEPGERGLKGHRGFT-----GLQGLPGPP 1076
Query: 1747 YPPQLMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGP 1806
P G G P G R P P P +G DG + GP
Sbjct: 1077 GPS-------------GDQGASGPAGPSGPRGPPGPVGP------SGKDGANGIPGPIGP 1117
Query: 1807 P----------TAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGP----PPPPLP 1852
P AG G P P PP P S+ L P E+GP P
Sbjct: 1118 PGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAF-AGLGPREKGPDPLQYMRADQAA 1176
Query: 1853 GPLAQPQASALATVKA 1868
G L Q A AT+K+
Sbjct: 1177 GGLRQHDAEVDATLKS 1192
Score = 67.8 bits (164), Expect = 1e-10
Identities = 245/1039 (23%), Positives = 303/1039 (29%), Gaps = 178/1039 (17%)
Query: 1107 KGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAAP----SEKNSIPIPTIIIKA 1162
+G V+Q +G+ + G + P P PQ P P +K P
Sbjct: 24 QGQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAP-----G 78
Query: 1163 PSTSSSGRSSQGSSTEAEPPTQPEPTGGGG-------GG----------GSSPSPAPAMS 1205
P + G+ PP P P G GG GG G P M
Sbjct: 79 PRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMG 138
Query: 1206 P-VPPSPSPVPTP----ASPSGPATLDFTSQFG----------------AALVGAARREG 1244
P PP P+ P P +P P + G A G A G
Sbjct: 139 PRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERG 198
Query: 1245 --GWQNEARRRSTLFLSTDAGDE--DGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLR 1300
G Q T L G G DG G APG + + G
Sbjct: 199 PPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRG 258
Query: 1301 LESAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAAR 1360
L G G AG+R G G + PP P V P G P +P A
Sbjct: 259 LPGERGRTGPAG-AAGARGNDGQPGPAG-----PPGP-VGPAGGPGF-PGAPGAKGEAGP 310
Query: 1361 ERALKESSEGGGAPQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARREL 1420
A EG P+ P P +P P +P P + +P
Sbjct: 311 TGA--RGPEGAQGPRGEPGTPG----SPGPAGASGNPGTDGIPGAKGSAGAP-------- 356
Query: 1421 GYRAGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSA 1480
G G P P A L + PG+ G + P PG + P +
Sbjct: 357 GIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGF---KGEQGPKGEPGPAGPQGAP 413
Query: 1481 APEEPERLPLHVRFLENCQPRAP-----VTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPR 1535
P E P P RG P +DG P +P P P+
Sbjct: 414 GPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPK 473
Query: 1536 -ASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPD 1594
A+ + G P P A + G+ P P PGPP P
Sbjct: 474 GANGDPGRPGEPGLPGARGLTGRPGD-------AGPQGKVGPSGAPGEDGRPGPPGPQGA 526
Query: 1595 TPAPATPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPA-- 1652
P + P P A P + G + A G P P GP
Sbjct: 527 RGQPG--VMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGER 584
Query: 1653 --PAAPAPAAPQ--PGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSA 1708
AP P+ Q PGP PPG + D + + A L E G
Sbjct: 585 GEQGAPGPSGFQGLPGPPGPPG--------EGGKPGDQGVPGEAGAPGLVGPRGE-RGFP 635
Query: 1709 GGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGL 1768
G G GA GP L G GP PP P L+G
Sbjct: 636 GERGSPGAQGLQGPRGLPGTPG-----TDGPKGASGPAGPPGAQGPPGLQGMPGERGAAG 690
Query: 1769 RPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPP-TAGVAGGPVAVEPEVPPVPL 1827
GP G R V P G DG L GPP AG G V P P
Sbjct: 691 IAGPKGD-RGDVGEKGPE---GAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGP---- 742
Query: 1828 PTASSLPRKLLPWEEGPGPPPPPL-----PGPLAQPQASALATVKASIISELSSKLQQFG 1882
A S + P E G PP P PG QP A + Q G
Sbjct: 743 --AGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKG-----------EQGEAGQKG 789
Query: 1883 GSSAAG----GALPWARGGSGGGGDSHHGGASYVPERTSSLQRQRLSDDSQSSLLSKPVS 1938
+ A G P +G +G G GA P T + + P S
Sbjct: 790 DAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGF--------PGAAGRVGPPGS 841
Query: 1939 SLFQNWPKPPLPPLPT---------GTGVSPTAAAAPGATSPSASSSSTSTRHLQGVEFE 1989
+ P PP PP P+ G P A PG P+ +G +
Sbjct: 842 N---GNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGE------KGEPGD 892
Query: 1990 MRPPLLRRAPSPSLLPASEHKVS-PAPR-PSSLPILPSGPLYPGLFDIRGSPTGGAGGSA 2047
P P P L V P R P LP PG +G+P GA G
Sbjct: 893 DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGK---QGAP--GASGDR 947
Query: 2048 DPFAPVFVPPHPGISGGLG 2066
P PV PG++G G
Sbjct: 948 GPPGPV---GPPGLTGPAG 963
Score = 66.2 bits (160), Expect = 3e-10
Identities = 168/648 (25%), Positives = 199/648 (30%), Gaps = 125/648 (19%)
Query: 1509 GPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLP 1568
GP DG P +P PP P P GL A D + G
Sbjct: 78 GPRGRDGEPGTPGNPGPPGPPGPPGP-----PGLGGNFAAQMAGGFDEKAGGAQL----- 127
Query: 1569 PPLEFSNSFEKPESPLTP-GPPHPL--------------PDTPAPATPLPPVPPPAVAAA 1613
+ P P+ P GPP P P P + P+ P PP
Sbjct: 128 ------GVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGK 181
Query: 1614 PPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDS 1673
P D A QGA PG P PG PG D G ++
Sbjct: 182 PGD-DGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRG------YPGLDGAKG-EA 233
Query: 1674 GIEEVDSRSSSDHPLETISSASTLSSLSAEG-GGSAGGGGGAGAGVASGPELLDTYVAYL 1732
G V S S P E S + G G G G AGA A G
Sbjct: 234 GAPGVKGESGS--PGENGSP----GPMGPRGLPGERGRTGPAGAAGARGN---------- 277
Query: 1733 DGQAFGGSSTPGPPYPPQLMTPSKLRG--RALGASGGLRP-------GPSGGLRDPVTPT 1783
DGQ PGP PP + P+ G A GA G P G G +P TP
Sbjct: 278 DGQ-------PGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPG 330
Query: 1784 SP-TVSVTG-AGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWE 1841
SP +G GTDG+ + +G P G+AG P P PP P L K E
Sbjct: 331 SPGPAGASGNPGTDGIPGAKGSAGAP--GIAGAPGFPGPRGPPGPQGATGPLGPKGQTGE 388
Query: 1842 EG-------------PGPP-PPPLPGPLAQPQASALATVKASIISELSSKLQQ------- 1880
G PGP P PGP A + A + + + ++
Sbjct: 389 PGIAGFKGEQGPKGEPGPAGPQGAPGP-AGEEGKRGARGEPGGVGPIGPPGERGAPGNRG 447
Query: 1881 FGGSSAAGG--ALPWARGGSGGGGDSHHGGASYVPERTSSLQRQRLSD-DSQSSLLSKPV 1937
F G G P RG SG G G P + L+ + K
Sbjct: 448 FPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVG 507
Query: 1938 SSLFQNWPKPPLPPLPTGTGVSPTAAAAPGATSPSASSSSTSTRHLQGVEFEMRPPLLRR 1997
S P PP P G P PG + + L G P LR
Sbjct: 508 PSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGA------PGLRG 561
Query: 1998 APSPS-----------LLPASEHKVSPAPRPSSLPILPSGPLYPGLFDIRGSPTGGAGGS 2046
P PA E AP PS LP P PG G G G
Sbjct: 562 LPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPG----EGGKPGDQGVP 617
Query: 2047 ADPFAPVFVPPHPGISGGLGGALSGASRSLSPTRLLSLPP--DKPFGA 2092
+ AP V P G G G S ++ L R L P D P GA
Sbjct: 618 GEAGAPGLVGPR-GERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGA 664
Score = 53.1 bits (126), Expect = 3e-06
Identities = 48/171 (28%), Positives = 62/171 (36%), Gaps = 25/171 (14%)
Query: 409 PFQESPKYAARRRGPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGS 468
P + P A +GP TG+T P A PGAA P ++G+
Sbjct: 794 PGPQGPSGAPGPQGP--TGVTGPKGARGAQGPPGAT-------GFPGAAGRVGPPGSNGN 844
Query: 469 QGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPREGPA 528
G P P+ K P+GAR S GR E + P G P G P +
Sbjct: 845 PGPPGPPGPSGK---------DGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGP 895
Query: 529 GGTGGSGGPGGSLGSRG-------RRRKLYSAVPGRSFMAVKSYQAQAEGE 572
G G GP G G RG R + + +PG S K A G+
Sbjct: 896 SGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGD 946
Score = 46.6 bits (109), Expect = 3e-04
Identities = 35/94 (37%), Positives = 43/94 (45%), Gaps = 22/94 (23%)
Query: 454 PGAASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQP 513
PG A G PGP + G P AP K +G P GAR ++G P
Sbjct: 281 PGPA--GPPGPVGPAGGPGFPGAPGAKGEAG-------PTGARGPEGAQG---------P 322
Query: 514 RGRPSSSGTPREGPAGGTGGSGGPG--GSLGSRG 545
RG P + G+P GPAG +G G G G+ GS G
Sbjct: 323 RGEPGTPGSP--GPAGASGNPGTDGIPGAKGSAG 354
Score = 45.1 bits (105), Expect = 8e-04
Identities = 48/144 (33%), Positives = 55/144 (38%), Gaps = 20/144 (13%)
Query: 418 ARRRGPPGT-GLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQSQPSA 476
A +G PG GL P + +T A P A GAPGP SG QG P
Sbjct: 548 AGEKGLPGAPGLRGLPG---KDGETGAAGPPGPAGPAGERGEQGAPGP-SGFQGLPGPPG 603
Query: 477 PTTKLSS----GTLRSASSP-----RGARARSPSRGRHPEDAKRQPRGRPSSSGTP---- 523
P + G A +P RG R RG + PRG P + GT
Sbjct: 604 PPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKG 663
Query: 524 REGPAGGTGGSGGPG--GSLGSRG 545
GPAG G G PG G G RG
Sbjct: 664 ASGPAGPPGAQGPPGLQGMPGERG 687
Score = 42.7 bits (99), Expect = 0.004
Identities = 42/135 (31%), Positives = 55/135 (40%), Gaps = 26/135 (19%)
Query: 414 PKYAARRRGPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGA-ASSGAPGPTSGSQGQS 472
P+ A RG PGT + PA N T PGA S+GAPG +G+ G
Sbjct: 316 PEGAQGPRGEPGTPGSPGPAGASGNPGTD---------GIPGAKGSAGAPG-IAGAPGFP 365
Query: 473 QPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPREGPAGGTG 532
P P + A+ P G + ++ G ++ P+G P GPAG G
Sbjct: 366 GPRGPPGP------QGATGPLGPKGQTGEPGIAGFKGEQGPKGEP--------GPAGPQG 411
Query: 533 GSGGPGGSLGSRGRR 547
G P G G RG R
Sbjct: 412 APG-PAGEEGKRGAR 425
Score = 42.7 bits (99), Expect = 0.004
Identities = 31/97 (31%), Positives = 39/97 (40%), Gaps = 10/97 (10%)
Query: 460 GAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSS 519
G PG T G +G S P+ P L+ RGA + +G + ++ P G P
Sbjct: 654 GTPG-TDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGK 712
Query: 520 SG-------TPREGPAGGTGGSG--GPGGSLGSRGRR 547
G GPAG G G GP G GS G R
Sbjct: 713 DGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGAR 749
Score = 42.7 bits (99), Expect = 0.004
Identities = 32/101 (31%), Positives = 40/101 (39%), Gaps = 10/101 (9%)
Query: 453 APGAASS-GAPGPTS-----GSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHP 506
APGA G+PGP G +G++ P R P+G R G
Sbjct: 997 APGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPG 1056
Query: 507 EDAKRQPRGRPSSSGTPREGPAGGTG--GSGGPGGSLGSRG 545
E + RG G P GP G +G G+ GP G G RG
Sbjct: 1057 ERGLKGHRGFTGLQGLP--GPPGPSGDQGASGPAGPSGPRG 1095
Score = 40.8 bits (94), Expect = 0.015
Identities = 51/172 (29%), Positives = 66/172 (38%), Gaps = 26/172 (15%)
Query: 411 QESPKYAARRRGPPG-TGLTVPPALLRANSDTSMALPDWMVFSA-----PGA-ASSGAPG 463
++ P+ A + G G TG PP AN + P SA PG +G PG
Sbjct: 703 EKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPG 762
Query: 464 PT--SGSQG-QSQPSAPTTKLSSGTLRSASSP-----RGARARSPSRGRHPEDAKRQPRG 515
P +G G QP A + +G A +P GA G R +G
Sbjct: 763 PAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQG 822
Query: 516 RPSSSGTP----REGPAGGTGGSG-----GPGGSLGSRGRRRKLYSAVPGRS 558
P ++G P R GP G G G GP G G +G R S PGR+
Sbjct: 823 PPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGD--SGPPGRA 872
Score = 38.1 bits (87), Expect = 0.094
Identities = 36/140 (25%), Positives = 48/140 (34%), Gaps = 6/140 (4%)
Query: 409 PFQESPKYAARRRGPPGTGLTVPPALLRANSD---TSMALPDWMVFSAPGAASSGAPGPT 465
P + PK A+ GPPG PP L + +A P GAPG
Sbjct: 656 PGTDGPKGASGPAGPPGA--QGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGK- 712
Query: 466 SGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPRE 525
G +G + P P + + P G + +RG E + P G +G P
Sbjct: 713 DGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGA 772
Query: 526 GPAGGTGGSGGPGGSLGSRG 545
G G G G G G
Sbjct: 773 DGQPGAKGEQGEAGQKGDAG 792
Score = 37.4 bits (85), Expect = 0.16
Identities = 30/94 (31%), Positives = 35/94 (37%), Gaps = 16/94 (17%)
Query: 454 PGAASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQP 513
PG A GAPGP +P P S P G R G+ +D +
Sbjct: 143 PGPA--GAPGPQGFQGNPGEPGEP----------GVSGPMGPRGPPGPPGKPGDDGEAGK 190
Query: 514 RGRPSSSGTPREGPAGGTGGSGGPG--GSLGSRG 545
G+ G P GP G G G PG G G RG
Sbjct: 191 PGKAGERGPP--GPQGARGFPGTPGLPGVKGHRG 222
Score = 37.4 bits (85), Expect = 0.16
Identities = 41/137 (29%), Positives = 52/137 (37%), Gaps = 24/137 (17%)
Query: 421 RGPPGT-GLTVPPALLRANSDTSMA--LPDWMVFSAPGAAS-SGAPGPTS-----GSQGQ 471
RGPPG G T P + +A + PG A GAPGP G++G+
Sbjct: 368 RGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGE 427
Query: 472 SQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSG-TPREGPAGG 530
P P G R +RG +D P+G P G + GP G
Sbjct: 428 PGGVGPI------------GPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGA 475
Query: 531 TGGSGGPG--GSLGSRG 545
G G PG G G+RG
Sbjct: 476 NGDPGRPGEPGLPGARG 492
Score = 37.0 bits (84), Expect = 0.21
Identities = 34/104 (32%), Positives = 42/104 (40%), Gaps = 15/104 (14%)
Query: 453 APGAASS-GAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKR 511
APGA+ G PGP G G + P+ + S A P G + +G E
Sbjct: 940 APGASGDRGPPGPV-GPPGLTGPAGEPGREGSP---GADGPPGRDGAAGVKGDRGETGAV 995
Query: 512 QPRGRPSSSGTPREGPAGGTG--------GSGGPGGSLGSRGRR 547
G P G+P GPAG TG G+ GP G G G R
Sbjct: 996 GAPGAPGPPGSP--GPAGPTGKQGDRGEAGAQGPMGPSGPAGAR 1037
Score = 36.6 bits (83), Expect = 0.27
Identities = 45/140 (32%), Positives = 53/140 (37%), Gaps = 30/140 (21%)
Query: 418 ARRRGPPGT----GLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPT--SGSQGQ 471
A RGPPG G P L D A G A GAPG SGS G+
Sbjct: 194 AGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLD----GAKGEA--GAPGVKGESGSPGE 247
Query: 472 SQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPRE-GPAGG 530
+ P R + P GA + +RG G+P +G P GPAGG
Sbjct: 248 NGSPGPMGPRGLPGERGRTGPAGA---AGARGND---------GQPGPAGPPGPVGPAGG 295
Query: 531 TGGSGGPG-----GSLGSRG 545
G G PG G G+RG
Sbjct: 296 PGFPGAPGAKGEAGPTGARG 315
Score = 36.6 bits (83), Expect = 0.27
Identities = 42/142 (29%), Positives = 50/142 (35%), Gaps = 19/142 (13%)
Query: 414 PKYAARRRGPPGTGLTVPPALLRANSDTSM----ALPDWMVFSA-PG-AASSGAPGPTS- 466
PK A RGP +GL P AN D LP + PG A G GP+
Sbjct: 457 PKGAPGERGP--SGLAGPKG---ANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGA 511
Query: 467 -GSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPRE 525
G G+ P P + P+GA G K P G P G P +
Sbjct: 512 PGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGE-----KGLP-GAPGLRGLPGK 565
Query: 526 GPAGGTGGSGGPGGSLGSRGRR 547
G G GP G G RG +
Sbjct: 566 DGETGAAGPPGPAGPAGERGEQ 587
Score = 36.6 bits (83), Expect = 0.27
Identities = 39/144 (27%), Positives = 47/144 (32%), Gaps = 12/144 (8%)
Query: 414 PKYAARRRGPPGT-------GLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTS 466
PK A +GPPG G PP P SG PG
Sbjct: 814 PKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAG 873
Query: 467 --GSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRG---RPSSSG 521
G QG + P + A P G + + RG +R RG P SG
Sbjct: 874 EPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSG 933
Query: 522 TPREGPAGGTGGSGGPGGSLGSRG 545
P + A G G GP G +G G
Sbjct: 934 EPGKQGAPGASGDRGPPGPVGPPG 957
Score = 36.2 bits (82), Expect = 0.36
Identities = 39/127 (30%), Positives = 43/127 (33%), Gaps = 15/127 (11%)
Query: 422 GPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQSQPSAPTTKL 481
GPPG P L N MA A GA GP G G P P
Sbjct: 93 GPPGPPGPPGPPGLGGNFAAQMA--GGFDEKAGGAQLGVMQGPM-GPMGPRGPPGPA--- 146
Query: 482 SSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTP-REGPAG--GTGGSGGPG 538
A P+G + G PRG P G P +G AG G G GP
Sbjct: 147 ------GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPP 200
Query: 539 GSLGSRG 545
G G+RG
Sbjct: 201 GPQGARG 207
Score = 35.8 bits (81), Expect = 0.47
Identities = 28/86 (32%), Positives = 32/86 (37%), Gaps = 13/86 (15%)
Query: 460 GAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSS 519
G PGP SG QG S P+ P S PRG G+ + P G P
Sbjct: 1074 GPPGP-SGDQGASGPAGP------------SGPRGPPGPVGPSGKDGANGIPGPIGPPGP 1120
Query: 520 SGTPREGPAGGTGGSGGPGGSLGSRG 545
G E G G+ GP G G G
Sbjct: 1121 RGRSGETGPAGPPGNPGPPGPPGPPG 1146
Score = 34.7 bits (78), Expect = 1.0
Identities = 35/128 (27%), Positives = 43/128 (33%), Gaps = 27/128 (21%)
Query: 421 RGPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQSQPSAPTTK 480
RGPPG PP + D P A G PGP P P K
Sbjct: 173 RGPPG-----PPG--KPGDDGEAGKPG-------KAGERGPPGPQGARGFPGTPGLPGVK 218
Query: 481 LSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPRE-GPAG--GTGGSGGP 537
RG ++G + G P +G+P GP G G G GP
Sbjct: 219 ----------GHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGP 268
Query: 538 GGSLGSRG 545
G+ G+RG
Sbjct: 269 AGAAGARG 276
Score = 34.3 bits (77), Expect = 1.4
Identities = 25/80 (31%), Positives = 26/80 (32%), Gaps = 13/80 (16%)
Query: 460 GAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSS 519
G PG G P P P G + RG E PRGR
Sbjct: 38 GEPGDIKDIVGPKGPPGP------------QGPAGEQGPRGDRGDKGEKGAPGPRGRDGE 85
Query: 520 SGTP-REGPAGGTGGSGGPG 538
GTP GP G G G PG
Sbjct: 86 PGTPGNPGPPGPPGPPGPPG 105
Score = 34.3 bits (77), Expect = 1.4
Identities = 26/92 (28%), Positives = 33/92 (35%), Gaps = 2/92 (2%)
Query: 460 GAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPS--RGRHPEDAKRQPRGRP 517
G+PGP S P K S+G A +P R P +G + G P
Sbjct: 330 GSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEP 389
Query: 518 SSSGTPREGPAGGTGGSGGPGGSLGSRGRRRK 549
+G E G G GP G+ G G K
Sbjct: 390 GIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGK 421
Score = 33.5 bits (75), Expect = 2.3
Identities = 27/82 (32%), Positives = 33/82 (40%), Gaps = 14/82 (17%)
Query: 454 PG-AASSGAPGPT--SGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAK 510
PG + GA GP SG +G P P+ K + + P G R RS G
Sbjct: 1076 PGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETG------- 1128
Query: 511 RQPRGRPSSSGTPREGPAGGTG 532
P G P + G P GP G G
Sbjct: 1129 --PAGPPGNPGPP--GPPGPPG 1146
Score = 33.1 bits (74), Expect = 3.0
Identities = 44/147 (29%), Positives = 53/147 (36%), Gaps = 19/147 (12%)
Query: 409 PFQESPKYAARRRGPPGT-GLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSG 467
P P+ G PG G PP A P M F P A+ G PG +G
Sbjct: 497 PGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ-----PGVMGFPGPKGAN-GEPGK-AG 549
Query: 468 SQGQSQPSAPTTKLSSGT--LRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPRE 525
+G P AP + G A+ P G + RG +G P G P E
Sbjct: 550 EKGL--PGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGE 607
Query: 526 GPAGGTGGSGGPG-----GSLGSRGRR 547
G G G G PG G +G RG R
Sbjct: 608 G--GKPGDQGVPGEAGAPGLVGPRGER 632
Score = 32.7 bits (73), Expect = 4.0
Identities = 27/88 (30%), Positives = 32/88 (36%), Gaps = 8/88 (9%)
Query: 460 GAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSP--RGARARSPSRGRHPEDAKRQPRGRP 517
GAPG SG +G P P G A P G+ GR + RG
Sbjct: 939 GAPG-ASGDRGPPGPVGPP-----GLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGET 992
Query: 518 SSSGTPREGPAGGTGGSGGPGGSLGSRG 545
+ G P G+ G GP G G RG
Sbjct: 993 GAVGAPGAPGPPGSPGPAGPTGKQGDRG 1020
Score = 32.3 bits (72), Expect = 5.2
Identities = 33/135 (24%), Positives = 40/135 (29%), Gaps = 18/135 (13%)
Query: 421 RGPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQSQPSAPTTK 480
RGPPG P + N PG + P G G+ K
Sbjct: 140 RGPPGPAGAPGPQGFQGNPGEP---------GEPGVSGPMGPRGPPGPPGKPGDDGEAGK 190
Query: 481 LSSGTLRSASSPRGARARSPS---------RGRHPEDAKRQPRGRPSSSGTPREGPAGGT 531
R P+GAR + RG D + G P G G+
Sbjct: 191 PGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGS 250
Query: 532 GGSGGPGGSLGSRGR 546
G GP G G RGR
Sbjct: 251 PGPMGPRGLPGERGR 265
Score = 31.6 bits (70), Expect = 8.8
Identities = 35/133 (26%), Positives = 41/133 (30%), Gaps = 21/133 (15%)
Query: 422 GPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASS-GAPGPTS--GSQGQSQPSAPT 478
GPPG P R +S PG A G GP G +G+ P+
Sbjct: 849 GPPGPSGKDGPKGARGDS------------GPPGRAGEPGLQGPAGPPGEKGEPGDDGPS 896
Query: 479 TKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTP----REGPAGGTGGS 534
+ + RG RG P G P G P GP G G
Sbjct: 897 GAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPP 956
Query: 535 G--GPGGSLGSRG 545
G GP G G G
Sbjct: 957 GLTGPAGEPGREG 969
Score = 31.6 bits (70), Expect = 8.8
Identities = 40/149 (26%), Positives = 53/149 (35%), Gaps = 29/149 (19%)
Query: 409 PFQESPKYAARRRGPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGP---- 464
P ++ A+ RGPPG PP L + +PGA G PG
Sbjct: 935 PGKQGAPGASGDRGPPGP--VGPPGLTGPAGEPGRE-------GSPGA--DGPPGRDGAA 983
Query: 465 -TSGSQGQS----QPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSS 519
G +G++ P AP S G P G + RG P G +
Sbjct: 984 GVKGDRGETGAVGAPGAPGPPGSPG-------PAGPTGKQGDRGEAGAQGPMGPSGPAGA 1036
Query: 520 SGTPR-EGPAGGTGGSGGPGGSLGSRGRR 547
G +GP G G +G PG G +G R
Sbjct: 1037 RGIQGPQGPRGDKGEAGEPG-ERGLKGHR 1064
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 107 bits (268), Expect = 1e-22
Identities = 155/554 (27%), Positives = 185/554 (33%), Gaps = 120/554 (21%)
Query: 1333 LPPRPLVHP--LTGKALDPASPLGLALAARERALK-ESSEGGGAPQPPPRPPSPRYEAPP 1389
LP RP P +G S + L ++ R +++ +S + + PP PPS + A
Sbjct: 763 LPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQ 822
Query: 1390 PTPHHHSPHA--------HHEPVLRLWGAS------PPDPARRELGYRAGLGSQEKSLPA 1435
P PH+ H V + S PP P GLG +P
Sbjct: 823 GQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGM----VPP 878
Query: 1436 SPPAARRSLLHRLPPTAPGVGPLLLQLGTE----PPAPHPGVSKPWRSAAPEEPERLPLH 1491
PP + LP TA P L GTE PP P PG P P LPL
Sbjct: 879 PPPPLPGMTVPTLPSTAIPQPPPLQ--GTEMLPPPPPPLPGAGIPPPPPLPGAGI-LPLP 935
Query: 1492 VRFLENCQPRAPVTSGRGPPSEDGPG----VPPPSPRRSVPPSPTSPRASEENGLPLLVL 1547
P P+ PP PG +PPP P +PP P P A G+P
Sbjct: 936 PLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGA----GIPP--- 988
Query: 1548 PPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPP 1607
PPP P + P PPPL + P P PG P P P P +PP PP
Sbjct: 989 PPPLPGAGI---------PPPPPLPGAGI---PPPPPLPGAGIP-PPPPLPGAGIPPPPP 1035
Query: 1608 PAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQ-PG-- 1664
A PP + + PG PP PP P A P P PG
Sbjct: 1036 LPGAGIPPPPPLPGAGIPP-----------PPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1084
Query: 1665 -PDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPE 1723
P PPP +GI P + G G GAG+ P
Sbjct: 1085 IPPPPPLPGAGIP----------PPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1134
Query: 1724 LLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGPSGGLRDPVTPT 1783
L G+ P PP P++ P P P G P P
Sbjct: 1135 L-------------PGAGIPPPPPLPRVGIPP--------------PPPLPGAGIPPPPP 1167
Query: 1784 SPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEV---PPVPLPTASSLPRKLLPW 1840
P GAG PP GV P P V PP PLP A P LP
Sbjct: 1168 LP-----GAGIP--------PPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPG 1214
Query: 1841 EEGPGPPPPPLPGP 1854
P P PPLP P
Sbjct: 1215 MGIPPAPAPPLPPP 1228
Score = 103 bits (258), Expect = 1e-21
Identities = 117/366 (31%), Positives = 130/366 (35%), Gaps = 62/366 (16%)
Query: 1330 TSFLPPRPLVHPLTGKALDPASPLGLALAARERALKESSEGGGAPQPPPRPPSPRYEAPP 1389
T LPP P PL G + P PL A L G G P PPP P + PP
Sbjct: 905 TEMLPPPP--PPLPGAGIPPPPPLPGAGILPLPPLP----GAGIPPPPPLPGAA-IPPPP 957
Query: 1390 PTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAARRSLLHRLP 1449
P P P P L G PP P G G +P PP + P
Sbjct: 958 PLPGAGIPLP---PPLPGAGIPPPPPL-------PGAG-----IPPPPPLPGAGIPP--P 1000
Query: 1450 PTAPGVG----PLLLQLGTEPPAPHPGVSKPWRSAAPEE--PERLPLHVRFLENCQPRAP 1503
P PG G P L G PP P PG P P P PL + P P
Sbjct: 1001 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI----PPPP 1056
Query: 1504 VTSGRG---PPSEDGPGVPPPSPR--RSVPPSPTSPRASEENGLPLLVLPPPAPSVDVED 1558
G G PP G G+PPP P +PP P P A G+P PPP P V +
Sbjct: 1057 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA----GIPP---PPPLPGVGIPP 1109
Query: 1559 GEFLFVEPLPPPLEFSNSFEKPESPLTPG----PPHPLPDT------PAPATPLPPVPPP 1608
L +PPP + P PL PG PP PLP P P +PP PP
Sbjct: 1110 PPPLPGAGIPPPPPLPGAGIPPPPPL-PGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPL 1168
Query: 1609 AVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPA-----APAPAAPQP 1663
A PP + PG PP PP P APAP P P
Sbjct: 1169 PGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPP 1228
Query: 1664 GPDPPP 1669
G PP
Sbjct: 1229 GTGIPP 1234
Score = 102 bits (253), Expect = 5e-21
Identities = 103/307 (33%), Positives = 111/307 (36%), Gaps = 60/307 (19%)
Query: 1337 PLVHPLTGKALDPASPLGLALAARERALKESSEGGGAPQPPPRP--------PSPRYEAP 1388
PL PL G + P PL A L G G P PPP P P P P
Sbjct: 965 PLPPPLPGAGIPPPPPLPGAGIPPPPPLP----GAGIPPPPPLPGAGIPPPPPLPGAGIP 1020
Query: 1389 PPTPHHHSPHAHHEPVLRLWGAS-PPDPARRELGYRAGLGSQEKSLPASPPAARRSLLHR 1447
PP P P A P L GA PP P G +P PP +
Sbjct: 1021 PPPP---LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP- 1076
Query: 1448 LPPTAPGVG----PLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPRAP 1503
PP PG G P L G PP P PGV P P LP P P
Sbjct: 1077 -PPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIP-------PPPPLP------GAGIPPPP 1122
Query: 1504 VTSGRG---PPSEDGPGVPPPSP--RRSVPPSPTSPRASEENGLPL----LVLPPPAPSV 1554
G G PP G G+PPP P R +PP P P A PL + PPP P V
Sbjct: 1123 PLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGV 1182
Query: 1555 DVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPG----PPHPLPDTPAPATPLPPVPPPAV 1610
+ P PPPL P P PG PP PLP P P PP+PPP
Sbjct: 1183 GI---------PPPPPLP---GVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGT 1230
Query: 1611 AAAPPTL 1617
PP L
Sbjct: 1231 GIPPPPL 1237
Score = 98.6 bits (244), Expect = 6e-20
Identities = 124/455 (27%), Positives = 155/455 (34%), Gaps = 69/455 (15%)
Query: 826 LAAAQQTISASESPGPGGLA-SLGKHRPKG----FFATESSFDPHHRAQPSYERPSFLPP 880
L + Q T S S+ P P L S G+ +P +TE H +++ +P
Sbjct: 798 LDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPS 857
Query: 881 GPGLMLRQKS-----IGAAEDDRPYLAPPAMKFSRSLSVP------GSEDIPPPPTTSP- 928
P L + S +G P L + S ++P G+E +PPPP P
Sbjct: 858 PPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPG 917
Query: 929 ----PEPPY--------------STPPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASF 970
P PP PP P G P P P PG+G PLP P +
Sbjct: 918 AGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPP---PPLPGAGIPLPPPLPGAG 974
Query: 971 DGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGG 1030
P PP G +PP PP PPP P PP PP G
Sbjct: 975 IPPPPPLPGAGIPPPPPLPGAGIPP----PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1030
Query: 1031 SPDDPPPRLALGPQPSLRGWRGGGPSPTPGA--PSPSHHGSAG-------GGGGSSQGPA 1081
P P P + P P L G P P PGA P P AG G G P
Sbjct: 1031 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1090
Query: 1082 LRYFQLPPRAASAAMYVPAR-----SGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPA 1136
L +PP + +P +G PL P G G+PP P
Sbjct: 1091 LPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVG 1150
Query: 1137 SPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQ----PEPTGGGG 1192
P PPP A P+P I P G PP P P G
Sbjct: 1151 IPPPPPLPGAGIPPPP-PLPGAGIPPPPPLP------GVGIPPPPPLPGVGIPPPPPLPG 1203
Query: 1193 GGGSSPSPAPAMSPVPPSPS-PVPTPASPSGPATL 1226
G P P P M +PP+P+ P+P P + P L
Sbjct: 1204 AGIPPPPPLPGMG-IPPAPAPPLPPPGTGIPPPPL 1237
Score = 97.1 bits (240), Expect = 2e-19
Identities = 116/401 (28%), Positives = 132/401 (32%), Gaps = 98/401 (24%)
Query: 1333 LPPRPLVHPLTGKALDPASPLGLALAARERALKESSEGGGAPQPPPRP--------PSPR 1384
+PP P PL G A+ P PL G G P PPP P P P
Sbjct: 942 IPPPP---PLPGAAIPPPPPL---------------PGAGIPLPPPLPGAGIPPPPPLPG 983
Query: 1385 YEAPPPTPHHHSPHAHHEPVLRLWGAS-PPDPARRELGYRAGLGSQEKSLPASPPAARRS 1443
PPP P P A P L GA PP P G +P PP
Sbjct: 984 AGIPPPPP---LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1040
Query: 1444 LLHRLPPTAPGVG----PLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQ 1499
+ PP PG G P L G PP P PG P P LP
Sbjct: 1041 IPP--PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP-------PPPPLPG-----AGIP 1086
Query: 1500 PRAPVTSGRGPPSEDGPGV----PPPSPRRSVPPSPTSPRASEENGLPL----LVLPPPA 1551
P P+ PP PGV PPP P +PP P P A PL + PPP
Sbjct: 1087 PPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1146
Query: 1552 PSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPG----PPHPLPDT------PAPATP 1601
P V + P PPPL + P P PG PP PLP P P
Sbjct: 1147 PRVGI---------PPPPPLPGAGI---PPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVG 1194
Query: 1602 LPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAP 1661
+PP PP A PP + + PG PP P P + P P
Sbjct: 1195 IPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLP-------PPGTGIPPPPLLPVSGPPLLP 1247
Query: 1662 QPG-------------PDPPPGTDSGIEEVDSRSSSDHPLE 1689
Q G P P P G+ + S P+E
Sbjct: 1248 QVGSSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIE 1288
Score = 91.7 bits (226), Expect = 7e-18
Identities = 236/1030 (22%), Positives = 327/1030 (31%), Gaps = 178/1030 (17%)
Query: 888 QKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPVPSSSGRLTP 947
Q++I + + L + + + G+E+ PPT P+P R
Sbjct: 200 QQAIRLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFL-----GLDRFLL 254
Query: 948 SPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHH 1007
P GG + + P PDT E++L LP +
Sbjct: 255 GPSGG----------------AGEAPGSPDT-----EQALSALSDLPES---------LA 284
Query: 1008 APPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHH 1067
A P +P PP P + +P P + A PS + P P G +
Sbjct: 285 AEPREPQ----QPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAF----PFPEAGPGEEAAG 336
Query: 1068 GSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLP 1127
G G + + F+ PR + + P G P ++ EP++ P
Sbjct: 337 APVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPE---VGEDAP----QRLGEEPEEEAQGP 389
Query: 1128 PAPSPTS-PASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPE 1186
AP+ S P SP APS++ P P I T++ SS S P P
Sbjct: 390 DAPAAASLPGSP-------APSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPR 442
Query: 1187 PTGGGGGGGSSPSPAPAMSPVPPSPSPVPTPASPSGPATLDFTSQFGAALVGAARREGGW 1246
P P++S S + + + A+P+ D L R W
Sbjct: 443 ---------IKRRPEPSLS--RGSRTALASVAAPAKKHRAD------GGLAAGLSRSADW 485
Query: 1247 QNEARRRSTLFLSTDAGDEDG--GDGGLGTGAAPGPRLRHSKSIDEG---MFSAEPYLR- 1300
E R+ + E G D G G A + + + +G +F+ L
Sbjct: 486 TEELGARTPRVGGSAHLLERGVASDSGGGVSPALAAKASGAPAAADGFQNVFTGRTLLEK 545
Query: 1301 -LESAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAA 1359
+G SR G F P + D A +
Sbjct: 546 LFSQQENGPPEEAEKFCSRIIAMGLLLPFSDCFREPCNQNAQTNAASFDQDQLYTWAAVS 605
Query: 1360 RERALKESSEGGGAPQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRE 1419
+ + SEG Q P R PS + PP H A E A P +R
Sbjct: 606 QPTHSLDYSEG----QFPRRVPSMGPPSKPPDEEHRLEDAETES----QSAVSETPQKRS 657
Query: 1420 LGYRAGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQ-------LGTEPPAPHPG 1472
+ +K + + +++ +L T + + + L TE + H G
Sbjct: 658 -------DAVQKEVVDMKSEGQATVIQQLEQTIEDLRTKIAELERQYPALDTEVASGHQG 710
Query: 1473 VSKPWRSAAPEEPERLPL------HVRFLENCQPRAPVTSGRG----PPSEDGPGVPPPS 1522
+ ++ E L L H R LE + T G PP + PG PP
Sbjct: 711 LENGVTASGDVCLEALRLEEKEVRHHRILEAKSIQTSPTEEGGVLTLPPVDGLPGRPPCP 770
Query: 1523 PRRS--------------VPPSPTSPRASEENGLPLLVLPPPAPSV--DVEDGEFLFVEP 1566
P V P S + + PPP PS+ G+ P
Sbjct: 771 PGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPP 830
Query: 1567 LPPPLEFSNSFEKPESPL------TPGPPHPLPDTPAPAT-----PLPPVPPPAVAAAPP 1615
EF S E S P PP PLP T + ++ +PP PPP P
Sbjct: 831 HSISTEFQTSHEHSVSSAFKNSCNIPSPP-PLPCTESSSSMPGLGMVPPPPPPLPGMTVP 889
Query: 1616 TLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAA---PAPAAPQPG-PDPPPGT 1671
TL STA L PG PP PP P A P P P G P PPP
Sbjct: 890 TLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLP 949
Query: 1672 DSGIEEVDSRSSSDHPL-ETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVA 1730
+ I + PL + A G G GAG+ P L
Sbjct: 950 GAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP----- 1004
Query: 1731 YLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPTVSVT 1790
G P PP P + P L +G P P G P P P
Sbjct: 1005 -------GAGIPPPPPLPGAGIPPPP----PLPGAGIPPPPPLPGAGIPPPPPLP----- 1048
Query: 1791 GAGTDGLLALRACSGPPTAGVAGGPVAVEPEV------PPVPLPTASSLPRKLLPWEEGP 1844
GAG L PP + G + P + PP PLP A P LP G
Sbjct: 1049 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP---GV 1105
Query: 1845 G-PPPPPLPG 1853
G PPPPPLPG
Sbjct: 1106 GIPPPPPLPG 1115
Score = 85.5 bits (210), Expect = 5e-16
Identities = 96/312 (30%), Positives = 110/312 (35%), Gaps = 68/312 (21%)
Query: 914 VPGSEDIPPPPTTS---PPEPPY---STPPVPSSSGRLTPSPRGGPFNPGSGGPLPASSP 967
+PG+ PPPP PP PP PP P G P P P PG+G P P P
Sbjct: 1036 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP---PPLPGAGIPPPPPLP 1092
Query: 968 ASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHPPHPPEME 1027
+ P PP VG +PP PP PPP P PP PP
Sbjct: 1093 GAGIPPPPPLPGVG-----------IPP----PPPLPGAGIPPPPPLPGAGIPPPPPLPG 1137
Query: 1028 TGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPALRYFQL 1087
G P P PR+ + P P L G P P PGA P G G P L +
Sbjct: 1138 AGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP--GVGIPPPPPLPGVGI 1195
Query: 1088 PPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAAP 1147
PP P G G P P G G+PPAP+P P PPP P
Sbjct: 1196 PP--------PPPLPGAGIPPP---------PPLPGMGIPPAPAP-----PLPPPGTGIP 1233
Query: 1148 SEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPT-----QPEPTGGGGGG-----GSS 1197
P P + + P GSST P P P+G G G GS
Sbjct: 1234 ------PPPLLPVSGPPL----LPQVGSSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSR 1283
Query: 1198 PSPAPAMSPVPP 1209
P P+ P
Sbjct: 1284 KQPIEPCRPMKP 1295
Score = 54.7 bits (130), Expect = 1e-06
Identities = 114/429 (26%), Positives = 138/429 (32%), Gaps = 73/429 (17%)
Query: 1658 PAAPQPGPDP-PPGTDSGIE--------------EVDSRSSSDHPLETISSASTLSSLSA 1702
P PG P PPG +SG + + + S P ++IS SL
Sbjct: 759 PVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLL- 817
Query: 1703 EGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGS-STPGPPYPPQLMTPSKLRGRA 1761
SAG G S T + AF S + P PP P + S + G
Sbjct: 818 ---WSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGL- 873
Query: 1762 LGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPE 1821
G+ P P L PT P+ ++ + PP G AG P
Sbjct: 874 -----GMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPG-AGIP------ 921
Query: 1822 VPPVPLPTASSLPRKLLPWEEGPG-PPPPPLPGPLAQPQASALATVKASIISELSSKLQQ 1880
PP PLP A LP LP G G PPPPPLPG P
Sbjct: 922 -PPPPLPGAGILPLPPLP---GAGIPPPPPLPGAAIPPPPPL------------------ 959
Query: 1881 FGGSSAAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQRQRLSDDSQSSLLSKPVSSL 1940
AG LP G+G GA P L + P
Sbjct: 960 ----PGAGIPLPPPLPGAGIPPPPPLPGAGIPP--PPPLPGAGIPPPPPLPGAGIPPPPP 1013
Query: 1941 FQNWPKPPLPPLPTGTGVSPTAAAAPGA----TSPSASSSSTSTRHLQGVEFEMRPPLLR 1996
PP PPLP G G+ P PGA P + L G PPL
Sbjct: 1014 LPGAGIPPPPPLP-GAGI-PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1071
Query: 1997 RA-PSPSLLPASEHKVSPAPRPSSLPILPSGPLYPGLFDIRGSPTGGAGGSADPFAP-VF 2054
P P LP + P P P +P P PG+ P GAG P P
Sbjct: 1072 AGIPPPPPLPGAG---IPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAG 1128
Query: 2055 VPPHPGISG 2063
+PP P + G
Sbjct: 1129 IPPPPPLPG 1137
Score = 37.0 bits (84), Expect = 0.21
Identities = 43/127 (33%), Positives = 48/127 (37%), Gaps = 19/127 (14%)
Query: 1947 PPLPPLPTGTGVSPTAAAAPGATSPSASSSSTSTRHLQGVEFEMRPPLLRRA-PSPSLLP 2005
PP PPLP G G+ P PGA P L GV PPL P P LP
Sbjct: 1075 PPPPPLP-GAGIPPPPPL-PGAGIPPPPP-------LPGVGIPPPPPLPGAGIPPPPPLP 1125
Query: 2006 ASEHKVSPA------PRPSSLPI--LPSGPLYPGLFDIRGSPTGGAGGSADPFAP-VFVP 2056
+ P P P LP +P P PG P GAG P P V +P
Sbjct: 1126 GAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIP 1185
Query: 2057 PHPGISG 2063
P P + G
Sbjct: 1186 PPPPLPG 1192
Score = 35.8 bits (81), Expect = 0.47
Identities = 82/352 (23%), Positives = 119/352 (33%), Gaps = 78/352 (22%)
Query: 875 PSFLPPGPGLMLRQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYS 934
P+ + P PG L AP + ++LS D+P P EP
Sbjct: 236 PTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSA--LSDLPESLAAEPREP--- 290
Query: 935 TPPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSP---PDTRVGSREKSLYHSG 991
+ PSP G P + LPA+ PA+ D PS P G E++
Sbjct: 291 ---------QQPPSPGGLPVSEAPS--LPAAQPAAKDSPSSTAFPFPEAGPGEEAA--GA 337
Query: 992 PLPPA---HHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLR 1048
P+ A AP P A PE+ +D P RL P+ +
Sbjct: 338 PVRGAGDTDEEGEEDAFEDAPRGSPGEEWA-----PEVG-----EDAPQRLGEEPEEEAQ 387
Query: 1049 GWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPALR--YFQLPPRAASAAMYVPARSGRGR 1106
G + PG+P+PS P + Y + R S+ + P++S
Sbjct: 388 GPDAPAAASLPGSPAPSQR-------CFKPYPLITPCYIKTTTRQLSSPNHSPSQS--PN 438
Query: 1107 KGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTS 1166
+ P +K+ P PS S S +VAAP++K+ +A
Sbjct: 439 QSPRIKRR-------------PEPS-LSRGSRTALASVAAPAKKH---------RADGGL 475
Query: 1167 SSGRSSQGSSTEAEPPTQPEPTGGG----------GGGGSSPSPAPAMSPVP 1208
++G S TE P G GGG SP+ A S P
Sbjct: 476 AAGLSRSADWTEELGARTPRVGGSAHLLERGVASDSGGGVSPALAAKASGAP 527
Score = 34.7 bits (78), Expect = 1.0
Identities = 63/253 (24%), Positives = 86/253 (33%), Gaps = 56/253 (22%)
Query: 1828 PTASSLPRKLLPWEEGPGPPPPPLPGPLAQPQASALATVKASIISE-LSSKLQQFGGSSA 1886
PT L P + PG PP P PG + PQ + + + +S +L + +
Sbjct: 748 PTEEGGVLTLPPVDGLPGRPPCP-PGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQS 806
Query: 1887 AGGALP-----WARGGSGGGGDSHHGGASYVPERTSSLQRQRLSDDSQSSLLSKPVSSLF 1941
P W+ G G H +S + Q+S VSS F
Sbjct: 807 ISQPPPPPSLLWSAGQGQPGSQPPHS----------------ISTEFQTSH-EHSVSSAF 849
Query: 1942 QNWPK-PPLPPLPT--------GTG-VSPTAAAAPGATSPSASSSSTSTRHLQGVEFEMR 1991
+N P PPLP G G V P PG T P+ S++
Sbjct: 850 KNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAI------------- 896
Query: 1992 PPLLRRAPSPSLLPASEHKVSPAPRPSSLPILPSGPLYPGLFDIRGSPTGGAGGSADPFA 2051
P P L +E + P P P +P P PG + P GAG P
Sbjct: 897 -------PQPPPLQGTE-MLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPL 948
Query: 2052 P-VFVPPHPGISG 2063
P +PP P + G
Sbjct: 949 PGAAIPPPPPLPG 961
Score = 31.6 bits (70), Expect = 8.8
Identities = 48/182 (26%), Positives = 62/182 (34%), Gaps = 28/182 (15%)
Query: 1887 AGGALPWARGGSGGGGD--SHHGGASYVPERTSSLQRQRLSDDSQSSLL----SKPVSSL 1940
A GA R SG D S H + Q RL Q L +
Sbjct: 166 AAGAQDGQRTSSGSDTDIYSFHSATEQEDLLSDIQQAIRLQQQQQQQLQLQLQQQQQQQQ 225
Query: 1941 FQNWPKPPLPPLPTGT-------------GVSPTAAAAPGATSPSASSSSTSTRHLQGVE 1987
Q +P PP G S A APG+ + S+ S + +
Sbjct: 226 LQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLP-ESLA 284
Query: 1988 FEMRPPLLRRAPSPSLLPASEHKVSPAPRPS-----SLPILPSGPLYPGLFDIRGSPTGG 2042
E R P ++ PSP LP SE PA +P+ S P PG + G+P G
Sbjct: 285 AEPREP--QQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPG-EEAAGAPVRG 341
Query: 2043 AG 2044
AG
Sbjct: 342 AG 343
>gi|30425444 ankyrin repeat and kinase domain containing 1 [Homo
sapiens]
Length = 765
Score = 101 bits (251), Expect = 9e-21
Identities = 71/202 (35%), Positives = 100/202 (49%), Gaps = 4/202 (1%)
Query: 193 DKVARLL-DKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMTAL 251
+ VARLL + DPN H+++ G+TPL +AA G V +++ L GA +D + R+ T L
Sbjct: 474 ENVARLLVSRQADPNLHEAE-GKTPLHVAAYF-GHVSLVKLLTSQGAELDAQQRNLRTPL 531
Query: 252 HKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGIAD 311
H A A+ LL G P+ D+ G PL HTA G C++LL A L +
Sbjct: 532 HLAVERGKVRAIQHLLKSGAVPDALDQSGYGPL-HTAAARGKYLICKMLLRYGASLELPT 590
Query: 312 ENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILLYRGA 371
GW +H A +GH + + L A GA A T LH+ A + +E LL GA
Sbjct: 591 HQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGA 650
Query: 372 DKDVKNNNGQTPFQVAVIAGNF 393
D + +G TP +AV F
Sbjct: 651 DPNAAEQSGWTPLHLAVQRSTF 672
Score = 96.7 bits (239), Expect = 2e-19
Identities = 105/396 (26%), Positives = 159/396 (40%), Gaps = 34/396 (8%)
Query: 62 MSVPDDAHFSMMVFRIGIPDLHQTKCLRFNPDATIWTAKQQVLCALSESLQDVLNYGLFQ 121
+++ D S++ R+ +P+ +K L ++V C LS +N + Q
Sbjct: 281 ITIETDILLSLLQSRVAVPE---SKALA-----------RKVSCKLSLRQPGEVNEDISQ 326
Query: 122 PATSGRDANFLEEERLLREYPQSFEKGVPYLEFRYKTR----VYKQTNLDEKQLAKLH-- 175
N+L+ L + + + K + Q ++++ +L H
Sbjct: 327 ELMDSDSGNYLKRALQLSDRKNLVPRDEELCIYENKVTPLHFLVAQGSVEQVRLLLAHEV 386
Query: 176 -----TKTGLKKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVI 230
T +G L Q D A LL G D N D D G PL AAQ G
Sbjct: 387 DVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADANRVDED-GWAPLHFAAQN-GDDGTA 444
Query: 231 RTLCLGGAHIDFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMV 290
R L GA +D + R+G T LH AA L+ PN + G TPL H A
Sbjct: 445 RLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKTPL-HVAAY 503
Query: 291 GGDPRCCELLLFNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTA 350
G +LL A+L N +H A +RG + ++HLL GA P A + SG
Sbjct: 504 FGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGP 563
Query: 351 LHICALYNKETCARILLYRGADKDVKNNNGQTPFQVAVIAGNFELGELI-RNHREQDVV- 408
LH A K ++LL GA ++ + G TP +A G+ E+ L+ +H +
Sbjct: 564 LHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALG 623
Query: 409 PFQESPKYAARRRGPPGTGLTVPPALLRANSDTSMA 444
+P + A R G V ALL+ +D + A
Sbjct: 624 AVNWTPLHLAARHGEE----AVVSALLQCGADPNAA 655
Score = 72.4 bits (176), Expect = 5e-12
Identities = 68/246 (27%), Positives = 100/246 (40%), Gaps = 17/246 (6%)
Query: 187 VQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARD 246
V+ G + LL G P+ D SG PL AA G + + L GA ++
Sbjct: 535 VERGKVRAIQHLLKSGAVPDALDQ-SGYGPLHTAA-ARGKYLICKMLLRYGASLELPTHQ 592
Query: 247 GMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQ 306
G T LH AA H + L + + TPL H A G+ LL A
Sbjct: 593 GWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPL-HLAARHGEEAVVSALLQCGAD 651
Query: 307 LGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARIL 366
A+++GW +H A QR + +LL + A A+N G T H+ AL ++L
Sbjct: 652 PNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALKGNTAILKVL 711
Query: 367 LYRGADKDVKNNNGQTPFQVAVIAGNFELGELIRNHREQDVVPFQE--SPKYAARRRGPP 424
+ GA DV++ TP Q+A+ R+Q ++ F E P A P
Sbjct: 712 VEAGAQLDVQDGVSCTPLQLAL------------RSRKQGIMSFLEGKEPSVATLGGSKP 759
Query: 425 GTGLTV 430
G + +
Sbjct: 760 GAEMEI 765
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 97.4 bits (241), Expect = 1e-19
Identities = 190/750 (25%), Positives = 263/750 (35%), Gaps = 177/750 (23%)
Query: 1173 QGSSTEAEPPTQPEPT---GGGGGGGSSPSPAPAMSPVPPSPSPVPTPASPSGPATLDFT 1229
+ + T A P T+P G GG G + +PAMS P + P T+D
Sbjct: 308 RSTGTRAPPLTRPMSLAVPGLTGGAGPAEPLSPAMSISPQATYLSKLIPHAVLPPTVDVV 367
Query: 1230 SQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKSID 1289
+ +L +R + A RS G + ++P PR RH S
Sbjct: 368 ALGRCSLRTLSRCSLHSASPASVRSL--------------GRFSSVSSPQPRSRHPSSSS 413
Query: 1290 EGMFSAEPYLRLESAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDP 1349
+ ++ + S GS G G S+A S +PP P G
Sbjct: 414 DTWSHSQSSDTIVSDGSTLSSKGGSEGQPE-----SSTASNSVVPP-----PQGGSGRGS 463
Query: 1350 ASPLGLALAARERALKESSEGGGAPQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWG 1409
S A A+ +++ S + G + P PPP HS H G
Sbjct: 464 PSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRP----PPPPRRTHSLHQR--------G 511
Query: 1410 ASPPDPARRELGYRAGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAP 1469
+ PD LG LP P ++ L R P T G G P P
Sbjct: 512 LAVPD---------GPLG-----LPPKPERKQQPQLPRPPTTGGSEGA-----GAAPCPP 552
Query: 1470 HP------GVSKPWRSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGPGV--PPP 1521
+P G+S P PER P + +S G P+ G+ PP
Sbjct: 553 NPANSWVPGLSPGGSRRPPRSPER---------TLSPSSGYSSQSGTPTLPPKGLAGPPA 603
Query: 1522 SPRRSVPPSPT------SPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSN 1575
SP ++ PP P SP AS + L L P+ G + PL +
Sbjct: 604 SPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILT-----PL--GD 656
Query: 1576 SFEKPESPLTPGPPHPLPDTP------APATPLPPVPPPAVAA------APPTLDSTASS 1623
F P P P P P P P APA P V P V+ +PPT +T +
Sbjct: 657 RFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTP 716
Query: 1624 LTSYDSEVATLTQGASAAPGDP---HPPGPP---------APAA---------------P 1656
L E +++ S P P HPP PP AP+A P
Sbjct: 717 L----QESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPP 772
Query: 1657 APAAPQ---------PGPD--------PPPGTDSGIEEVDSRSSSDHPLETISSASTLSS 1699
P AP+ P P+ P P SG E+ S ++ SS++T
Sbjct: 773 PPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAAS------SSSATALQ 826
Query: 1700 LSAEGGGSAGGGGGAGAGVASGPELLDTYVAYL-DGQAFGGSSTPGPPYPP---QLMTPS 1755
+ G A A +S P +VA L + G S GPP L+TPS
Sbjct: 827 IQPPGSPDPPPAPPAPAPASSAPG----HVAKLPQKEPVGCSKGGGPPREDVGAPLVTPS 882
Query: 1756 KL---RGRALGASGGLRPGPSGG-------LRDPVTPTSPTVSVTGAGTDGLLALRACSG 1805
L R R++GA GG P P+ G LR ++ + V +G + L+ACS
Sbjct: 883 LLQMVRLRSVGAPGGA-PTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSL 941
Query: 1806 PPTAGVA----GGPVAVEPEVPPVPLPTAS 1831
+ G++ GP EP P P TAS
Sbjct: 942 AASEGLSSAQPNGPPEAEPRPPQSPASTAS 971
Score = 72.8 bits (177), Expect = 3e-12
Identities = 170/712 (23%), Positives = 233/712 (32%), Gaps = 108/712 (15%)
Query: 1016 HHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGG 1075
H A P + S P PR + P S W S T + GS G
Sbjct: 383 HSASPASVRSLGRFSSVSSPQPR-SRHPSSSSDTWSHSQSSDTIVSD-----GSTLSSKG 436
Query: 1076 SSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEP---QKGGGLPP-APS 1131
S+G Q AS ++ P + G GR P T + + G L + S
Sbjct: 437 GSEG------QPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVS 490
Query: 1132 PTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGG 1191
P PPP + + +P + P + Q PPT TGG
Sbjct: 491 LRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQ----LPRPPT----TGGS 542
Query: 1192 GGGGSSPSPA-PAMSPVP---------PSPSPVPTPASPSGPATLDFTSQFGA------A 1235
G G++P P PA S VP P SP T + SG ++SQ G
Sbjct: 543 EGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSG-----YSSQSGTPTLPPKG 597
Query: 1236 LVGAARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGM--- 1292
L G G Q R T S A + + P P R I +
Sbjct: 598 LAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDR 657
Query: 1293 FSAEPYLRLESAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPASP 1352
F P+ ++ + S S+ + A + P + P++ P SP
Sbjct: 658 FVIPPHPKVPAPFSPPP-------SKPRSPNPAAPALAA---PAVVPGPVSTTDASPQSP 707
Query: 1353 LGLALAARERALKESSEGGGAPQPPPRPPSPRYEAPPPTPHHH----SPHAHH---EPVL 1405
L+ES PPP PP + PPPT +P A EP+
Sbjct: 708 PTPQTTLTP--LQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQ 765
Query: 1406 RLWGASPPDPARRELGYRAGLGSQEKSLPASPPAARRSLLHRLP-PTAPGVGPLLLQ--- 1461
PP PA E Q+ S+ PP P P P P L+
Sbjct: 766 DPNWPPPPPPAPEE---------QDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPA 816
Query: 1462 --------LGTEPP-APHPGVSKPWRSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPPS 1512
L +PP +P P + P AP P HV L +P + G GPP
Sbjct: 817 ASSSSATALQIQPPGSPDPPPAPP----APAPASSAPGHVAKLPQKEP-VGCSKGGGPPR 871
Query: 1513 EDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPP-- 1570
ED G P +P S+ G P L P AP + P+P P
Sbjct: 872 ED-VGAPLVTP--SLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSS 928
Query: 1571 -LEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPAVAA-------APPTLDSTAS 1622
L + + + G P+ P A P PP P + A+ L+ S
Sbjct: 929 GLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVS 988
Query: 1623 SLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPD-PPPGTDS 1673
T D + + + S + P +P AP P A +P PPP + S
Sbjct: 989 PETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPS 1040
Score = 66.6 bits (161), Expect = 2e-10
Identities = 162/702 (23%), Positives = 214/702 (30%), Gaps = 139/702 (19%)
Query: 831 QTISASESPGPGGLASLGKHRPKGFFATESSFDPHHRAQPSYERPSFL-------PPGPG 883
++ +AS S P G+ P G E+S R+ S PP P
Sbjct: 443 ESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPR 502
Query: 884 LMLRQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPVPSSSG 943
G A D P PP + + +P PPTT E + P P+ +
Sbjct: 503 RTHSLHQRGLAVPDGPLGLPPKPERKQQ------PQLPRPPTTGGSEGAGAAPCPPNPAN 556
Query: 944 RLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHH 1003
P +PG G P SP PS S S + LPP P
Sbjct: 557 SWVPG-----LSPG-GSRRPPRSPERTLSPS-------SGYSSQSGTPTLPPKGLAGPPA 603
Query: 1004 HHHHAPPPQPHHHHAHPPHPPEMETG-----GSPDDPPPRLALGPQP-SLRGWRGGGPSP 1057
A PP+P + + + S DP P GPQ + G R P P
Sbjct: 604 SPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIP-P 662
Query: 1058 TPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVE 1117
P P+P + + PAL + P S P + P T ++
Sbjct: 663 HPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASP----QSPPTPQTTLTPLQ 718
Query: 1118 GEPQKGGGLPPAPSPTSPASPQPPPA------VAAPSEKNSIPIPTIIIKAPSTSSSGRS 1171
P P PSP P PPP V APS + P P
Sbjct: 719 ESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPE 778
Query: 1172 SQGSSTEAEPPTQ--------PEPTGGGGGGGSSPSPAPAMS--------------PVPP 1209
Q S PP + PEP G G SPA + S P P
Sbjct: 779 EQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPA 838
Query: 1210 SPSPVPTPASPSGPATLDFTSQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDEDGGD 1269
P+P P ++P A L G + G RE D G
Sbjct: 839 PPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPRE-----------------DVG------ 875
Query: 1270 GGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGAGSRAYGGGGGSSAF 1329
P + S +RL S G+ G G A
Sbjct: 876 ---------APLVTP---------SLLQMVRLRSVGAPGGAPTPALGPSA---------- 907
Query: 1330 TSFLPPRPLVHPLTGKALD-PASPLGLALAARERALKESSEGGGAPQPPPRPPSPRYEAP 1388
P +PL L+G+A PA GL A R +A ++ G + P PP P
Sbjct: 908 ----PQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAE-PRP 962
Query: 1389 PPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAARRSLLHRL 1448
P +P + + +L P P + L + A RS+ +
Sbjct: 963 PQSPASTASFIFSKGSRKLQLERPVSP------------ETQADLQRNLVAELRSISEQR 1010
Query: 1449 PPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPL 1490
PP AP P P A P V P A+P P PL
Sbjct: 1011 PPQAPKKSP----KAPPPVARKPSVGVP-PPASPSYPRAEPL 1047
Score = 60.1 bits (144), Expect = 2e-08
Identities = 157/617 (25%), Positives = 214/617 (34%), Gaps = 141/617 (22%)
Query: 1510 PPSEDGPGVPPPSPRRSVPPSPT-SPRASEENG-----LPLLVLPPPAP---------SV 1554
PP + G G PS + S T S R+S + L L PPP P +
Sbjct: 453 PPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGL 512
Query: 1555 DVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHP--LPDTPAPATPLPPVPPPAVAA 1612
V DG LPP E + P P T G P P PA P P +
Sbjct: 513 AVPDGPL----GLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSR 568
Query: 1613 APP-TLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGT 1671
PP + + T S + Y S+ T P PP A PA+P P P
Sbjct: 569 RPPRSPERTLSPSSGYSSQSGT-------------PTLPPKGLAGPPASPGKAQPPKP-- 613
Query: 1672 DSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAY 1731
E V S S S +S+L+SL + A SGP++L
Sbjct: 614 ----ERVTSLRSPG-----ASVSSSLTSLCSSSSDPAPSD-------RSGPQILTPL--- 654
Query: 1732 LDGQAF---GGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGP-SGGLRDPVTPTSPTV 1787
G F P P PP S A+ + PGP S P +P +P
Sbjct: 655 --GDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQT 712
Query: 1788 SVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPP-------VPLPTASSLPRKLLPW 1840
++T +++ + S PP+ P + P PP V P+AS + P
Sbjct: 713 TLTPLQESPVIS-KDQSPPPSP-----PPSYHPPPPPTKKPEVVVEAPSASETAEE--PL 764
Query: 1841 EEGPGPPPPPLPGPLAQPQASALATVKASIISELSSKLQQFGGSSAAGGALPWARGGSGG 1900
++ PPPPP P P Q + A ++S P G SG
Sbjct: 765 QDPNWPPPPP-PAPEEQDLSMADFPPPEEAFFSVAS---------------PEPAGPSGS 808
Query: 1901 GGDSHHGGASYVPERTSSLQRQRLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGVSP 1960
PE SS S S ++L +P S PP PP P
Sbjct: 809 ------------PELVSS---PAASSSSATALQIQPPGSP----DPPPAPPAPA------ 843
Query: 1961 TAAAAPGATSPSASSSSTSTRHLQGVEFE-MRPPLLRRAPSPSLLPASEHKVSPAPRPSS 2019
A++APG + G E + PL+ +PSLL + AP +
Sbjct: 844 PASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLV----TPSLLQMVRLRSVGAPGGAP 899
Query: 2020 LPIL-PSGPLYPGLFDIRGSPTGGAGGSADPFAPVFVPPHPGISGGLGGALSGASRSLSP 2078
P L PS P P +R + +G A P P S GL A+ + SL+
Sbjct: 900 TPALGPSAPQKP----LRRALSGRAS------------PVPAPSSGLHAAVRLKACSLAA 943
Query: 2079 TR-LLSLPPDKPFGAKP 2094
+ L S P+ P A+P
Sbjct: 944 SEGLSSAQPNGPPEAEP 960
Score = 58.9 bits (141), Expect = 5e-08
Identities = 121/520 (23%), Positives = 167/520 (32%), Gaps = 79/520 (15%)
Query: 760 PDMDEAVHKKAPQQAKRLPPPTISLRSKSMTSELEEMEYEQQPAPVPSMEKKRTVYQMAL 819
P + ++ P+ +R P+ S+S T L PA + + +L
Sbjct: 560 PGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSL 619
Query: 820 NKLDEILAAAQQTISASESP-------GPGGLASLGKHR--------PKGFFATESSFDP 864
++++ ++ +S S GP L LG P F S
Sbjct: 620 RSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRS 679
Query: 865 HHRAQPSYERPSFLPPGPGLMLRQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPP 924
+ A P+ P+ +P GP + P ++ S +S S PPP
Sbjct: 680 PNPAAPALAAPAVVP-GP---VSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPP 735
Query: 925 TTSPPEPPYSTPPV----PSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRV 980
+ PP PP P V PS+S P P P P P S PP+
Sbjct: 736 SYHPPPPPTKKPEVVVEAPSAS-ETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPE--- 791
Query: 981 GSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLA 1040
E + P P P +P A PP GSPD PP A
Sbjct: 792 ---EAFFSVASPEPAGPSGSPELVS--SPAASSSSATALQIQPP-----GSPDPPPAPPA 841
Query: 1041 LGPQPSLRGW-------------RGGGPSPTP-GAP--SPS--------HHGSAGGGGGS 1076
P S G +GGGP GAP +PS G+ GG
Sbjct: 842 PAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTP 901
Query: 1077 SQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPA 1136
+ GP+ L + A VPA S +K + P P P
Sbjct: 902 ALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPR 961
Query: 1137 SPQPPPAVAA-----PSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGG 1191
PQ P + A+ S K + P + + S +E PP P+
Sbjct: 962 PPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPK----- 1016
Query: 1192 GGGGSSPSPAPAMSPVPPSPS-PVPTPASPSGPATLDFTS 1230
SP P PV PS VP PASPS P T+
Sbjct: 1017 ----KSPKAPP---PVARKPSVGVPPPASPSYPRAEPLTA 1049
Score = 58.2 bits (139), Expect = 9e-08
Identities = 135/593 (22%), Positives = 184/593 (31%), Gaps = 94/593 (15%)
Query: 1508 RGPPSEDGP-GVPPPSPRRSVPPSPTSPRASEENGLPLLVLPP-PAPSVDVEDGEFLFVE 1565
RG DGP G+PP R+ P P P G PP PA S
Sbjct: 510 RGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANS------------ 557
Query: 1566 PLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPV----PPPAVAAAPPTLDSTA 1621
P L S P SP P + + LPP PP + A P
Sbjct: 558 -WVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERV 616
Query: 1622 SSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSR 1681
+SL S + V++ ++ DP P P P + P P + S+
Sbjct: 617 TSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSK 676
Query: 1682 SSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGSS 1741
S +P +A + G A S P T +
Sbjct: 677 PRSPNPAAPALAAPAVVP---------GPVSTTDASPQSPPTPQTTLTPLQESPVISKDQ 727
Query: 1742 TPGPPYPPQLMTPSK--LRGRALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGL-- 1797
+P P PP P + + + L+DP P P +
Sbjct: 728 SPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADF 787
Query: 1798 ----LALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPG 1853
A + + P AG +G P V P ASS L + PG P PP
Sbjct: 788 PPPEEAFFSVASPEPAGPSGSPELVSS-------PAASSSSATALQIQP-PGSPDPPPAP 839
Query: 1854 PLAQPQASA----------------------LATVKASIISELSSKLQQFGGSSAAGGAL 1891
P P +SA V A +++ ++ + A GGA
Sbjct: 840 PAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAP 899
Query: 1892 PWARGGSGGGGDSHH---GGASYVPERTSSLQRQ-RLSDDSQSSLLSKPVSSLFQNW--- 1944
A G S G AS VP +S L RL S ++ S+ +SS N
Sbjct: 900 TPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAA--SEGLSSAQPNGPPE 957
Query: 1945 --PKPPLPPLPTGT-----GVSPTAAAAPGATSPSASSSSTSTRHLQGVEFEMRPPLLRR 1997
P+PP P T + G P + A L+ + E RPP +
Sbjct: 958 AEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSIS-EQRPP---Q 1013
Query: 1998 AP--SPSLLPASEHKVSPAPRPSSLPILPSGPLYPGLFDIRGSPTGGAGGSAD 2048
AP SP P K S P P+ P YP + PT G + D
Sbjct: 1014 APKKSPKAPPPVARKPSVGVPP------PASPSYPRAEPLTAPPTNGLPHTQD 1060
Score = 46.2 bits (108), Expect = 3e-04
Identities = 89/361 (24%), Positives = 122/361 (33%), Gaps = 88/361 (24%)
Query: 859 ESSFDPHHRAQPSYERPSFLPPGPGLMLRQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSE 918
ES ++ P PS+ PP P +P + A S + P +
Sbjct: 719 ESPVISKDQSPPPSPPPSYHPPPP------------PTKKPEVVVEAPSASETAEEPLQD 766
Query: 919 -DIPPPPTTSPPEPPYST----PPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGP 973
+ PPPP +P E S PP + +P P G SG P SSPA+
Sbjct: 767 PNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGP-----SGSPELVSSPAA---S 818
Query: 974 SPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPD 1033
S T + + P PPA H A PQ P E G+P
Sbjct: 819 SSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPL 878
Query: 1034 DPP-----------------PRLALGP---QPSLRGWRGGGPSPTPGAPSPSHHGS---- 1069
P P ALGP Q LR G SP P APS H +
Sbjct: 879 VTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVP-APSSGLHAAVRLK 937
Query: 1070 -----AGGGGGSSQ--GPALRYFQLPPRAASAAMYVPARSGRGRK--GPLVKQTKVEGE- 1119
A G S+Q GP + P AS A ++ ++ R + P+ +T+ + +
Sbjct: 938 ACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQR 997
Query: 1120 -----------------PQKGGGLPP---------APSPTSPASPQPPPAVAAPSEKNSI 1153
P+K PP P P SP+ P+ P A P+ N +
Sbjct: 998 NLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPT--NGL 1055
Query: 1154 P 1154
P
Sbjct: 1056 P 1056
Score = 42.0 bits (97), Expect = 0.007
Identities = 91/352 (25%), Positives = 128/352 (36%), Gaps = 71/352 (20%)
Query: 1770 PGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPT 1829
PG +GG P P SP +S++ T + PPT V + L +
Sbjct: 326 PGLTGGA-GPAEPLSPAMSISPQATYLSKLIPHAVLPPTVDVVALGRCSLRTLSRCSLHS 384
Query: 1830 ASSLPRKLLPWEEGPGPPPPPLPGPLAQPQASALATVKASIISELSSKLQQFGGS----- 1884
AS + L P P P + + + +I+S+ S L GGS
Sbjct: 385 ASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSD-GSTLSSKGGSEGQPE 443
Query: 1885 --SAAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQRQRLSDDSQSSL--LSKP---- 1936
+A+ +P +GGSG G S GG++ T S++ SL L +P
Sbjct: 444 SSTASNSVVPPPQGGSGRGSPS--GGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPP 501
Query: 1937 --VSSLFQNW-----------PKP-----PLPPLPTGTGVSPTAAAAPGATSPSAS---- 1974
SL Q PKP P P P TG S A AAP +P+ S
Sbjct: 502 RRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPG 561
Query: 1975 -SSSTSTRHLQGVEFEMRPP--LLRRAPSPSL-------LPASEHKVSPAPRPSSLPILP 2024
S S R + E + P ++ +P+L PAS K P P+P + L
Sbjct: 562 LSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQP-PKPERVTSLR 620
Query: 2025 SGPLYPGLFDIRGSPTGGAGGSADPFAP---------------VFVPPHPGI 2061
S PG + S T S+DP AP +PPHP +
Sbjct: 621 S----PGA-SVSSSLTSLCSSSSDP-APSDRSGPQILTPLGDRFVIPPHPKV 666
Score = 35.8 bits (81), Expect = 0.47
Identities = 36/129 (27%), Positives = 45/129 (34%), Gaps = 27/129 (20%)
Query: 420 RRGPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQSQPSAPTT 479
+R PP PP + +A+PD + G P Q P PTT
Sbjct: 495 KRPPP------PPRRTHSLHQRGLAVPDGPL---------GLPPKPERKQQPQLPRPPTT 539
Query: 480 KLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPR----------GRPSSSGTPREGPAG 529
S G + P A + P G P ++R PR G S SGTP P G
Sbjct: 540 GGSEGAGAAPCPPNPANSWVP--GLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKG 597
Query: 530 GTGGSGGPG 538
G PG
Sbjct: 598 LAGPPASPG 606
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 96.7 bits (239), Expect = 2e-19
Identities = 145/629 (23%), Positives = 208/629 (33%), Gaps = 138/629 (21%)
Query: 1271 GLGTGAAPGPRLRHSKSIDEGMFSAEP--YLRLESAGSGAGYGGYGAGSRAYGGGGG--- 1325
G + + P + HS D G+ +P ++R +S S + G++
Sbjct: 537 GSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKARME 596
Query: 1326 --SSAFTSFLPPRP----LVHPLTGKALDPASPLGLALAARERALKESSEGGGAPQPPPR 1379
+ +TS +PP +V P T P P P PPP
Sbjct: 597 SMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLP-------------------PPPPPPPP 637
Query: 1380 PPSPRYEAPPPTPHHHSPHA--------HHEPVLRLWGAS---------PPDPARRELGY 1422
PP P PPP P +P A + + RL AS P P +
Sbjct: 638 PPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSV 697
Query: 1423 RAGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAP 1482
+ + + PP PP P G + QL P AP S P SA P
Sbjct: 698 KPQILVPPNGVVPPPPP---------PPPPPTPGSAMAQLKPAPCAP----SLPQFSAPP 744
Query: 1483 EEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGL 1542
PL + +++ AP P PPP P P+P P+A +
Sbjct: 745 P-----PLKIHQVQHITQVAP------------PTPPPPPPI----PAPLPPQAPPK--- 780
Query: 1543 PLLVLPPPAPSVDVEDGEFLFVEPLP----PPLEFSNSFEK---PESPLTPGPPHPLPDT 1595
PL+ +P P + V P P PP + +F P SP TP P P P
Sbjct: 781 PLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTL 840
Query: 1596 PAPATPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAA 1655
P + PP ++ P + AS + A +Q P + P PPA A
Sbjct: 841 PKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKA 900
Query: 1656 ----------------------------PAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHP 1687
P P +P P P PPP + S S
Sbjct: 901 KPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKT 960
Query: 1688 LETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGS----STP 1743
+T S + + S GA P +D+ V+ A GS + P
Sbjct: 961 SKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPS-VDSLVSKFTPPAESGSPSKETLP 1019
Query: 1744 GPPYPPQLMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRAC 1803
P PP+ P KL + G L+ G V+ +P +S G G D ++
Sbjct: 1020 PPAAPPK---PGKLNLSGVNLPGVLQQG-------CVSAKAPVLS--GRGKDSVVEFP-- 1065
Query: 1804 SGPPTAGVAGGPVAVEPEVPPVPLPTASS 1832
S P + P E +PP+ +P S
Sbjct: 1066 SPPSDSDFPPPPPETELPLPPIEIPAVFS 1094
Score = 75.9 bits (185), Expect = 4e-13
Identities = 105/415 (25%), Positives = 139/415 (33%), Gaps = 94/415 (22%)
Query: 883 GLMLRQKSIGAAED-DRPY--LAPP-------AMKFSRSLSVPGSEDIPPPPTTSPPEPP 932
G L + S E +RPY L PP ++ S P PPPP PP PP
Sbjct: 584 GTQLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPP 643
Query: 933 YSTPPVPSSSGRLTPSPRGGPFNPGSGGPL-------------PASSPASFDGPSPPDTR 979
PP+PS S PS GS P+ S A F P+PP +
Sbjct: 644 PPPPPLPSQSA---PSA-------GSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQ 693
Query: 980 VGSREKSLY--HSGPLPPAHHHPPHHHHHHA-------------------PPPQPHHHHA 1018
S + + +G +PP PP A PPP H
Sbjct: 694 SQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQ 753
Query: 1019 H--------PPHPPEMETGGSPDDPPPRLALGPQPSLRGW------RGGGPSPTPGAPSP 1064
H PP PP + P PP L P P+ + P+PTP P
Sbjct: 754 HITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPP- 812
Query: 1065 SHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGG 1124
+ + PA +PP + + VP + L KQ +P
Sbjct: 813 -----------AKKQPAFPASYIPPSPPTPPVPVPPPT-------LPKQQSFCAKPPPSP 854
Query: 1125 GLPPAPSPTSPASPQ--PPPAVAAPSEKNSIPIPTIII-KAPSTSSSGRSSQGSSTEAEP 1181
L P PS + Q PPP A + P+P + ++P + Q SS
Sbjct: 855 -LSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPS 913
Query: 1182 PTQPEPTGGGGGGGSSPSPAPAMSPVPPSP---SPVPTPASPSGPATLDFTSQFG 1233
P P P P P+P +P PP P SP P + G T +S G
Sbjct: 914 PDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGG 968
Score = 68.2 bits (165), Expect = 9e-11
Identities = 85/372 (22%), Positives = 122/372 (32%), Gaps = 72/372 (19%)
Query: 903 PPAMKFSR---SLSVPGSEDIPPPPTTSPPEPP------------------YSTPPVPSS 941
PP M+ + VP + +PPPP PP P +S PP P
Sbjct: 689 PPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLK 748
Query: 942 SGRLTPSPRGGPFNPGSGGPLPASSPASFDG------PSPPDTR----VGSREKSLYHSG 991
++ + P P P+PA P P+P T+ V ++ +
Sbjct: 749 IHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTP 808
Query: 992 PLPPAHHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWR 1051
P+PPA P + P P PP P+ ++ + P P L P PS+
Sbjct: 809 PVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSP---LSPVPSVVKQI 865
Query: 1052 GGGPSPTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLV 1111
P P P+ PA Q PP + + P+ P+
Sbjct: 866 ASQFPPPPTPPAMESQPL-------KPVPANVAPQSPPAVKAKPKWQPSSI------PVP 912
Query: 1112 KQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRS 1171
P+ PP P PA P PPP A+P+ S +P +S S
Sbjct: 913 SPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKS--------GSPGKKTSKTS 964
Query: 1172 SQGSSTEAEPPTQPEPTGG--GGGGGSSPSP------------APAMSPVPPSPSPVPTP 1217
S G +PP P+ G P P P PS +P P
Sbjct: 965 SPGGK---KPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPP 1021
Query: 1218 ASPSGPATLDFT 1229
A+P P L+ +
Sbjct: 1022 AAPPKPGKLNLS 1033
Score = 56.2 bits (134), Expect = 3e-07
Identities = 92/353 (26%), Positives = 118/353 (33%), Gaps = 76/353 (21%)
Query: 879 PPGPGLMLRQKSIGAAEDDRPYLAPPAMKFS-----RSLSVPGSEDIPPPPTTS---PPE 930
PP P M Q + P +PPA+K S+ VP + PPPP +S PP
Sbjct: 872 PPTPPAMESQPLKPVPANVAPQ-SPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPP 930
Query: 931 PPYSTPPVPSSSGRLTPSPRGGPFNPGSGGP-LPASSPASFDGPSPPDTRVGSREKSLYH 989
PP P P P P P SG P S +S G PP T R S+
Sbjct: 931 PPSPVPAPPP-----PPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPT--PQRNSSIKS 983
Query: 990 SGPLPPAHHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRG 1049
S H P +P P E+G + P A P+P
Sbjct: 984 SSGA------------EHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKP---- 1027
Query: 1050 WRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGP 1109
G G P G G S++ P L SGRG
Sbjct: 1028 ----GKLNLSGVNLP---GVLQQGCVSAKAPVL-------------------SGRG---- 1057
Query: 1110 LVKQTKVE-GEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSS 1168
K + VE P PP P T P PP + A N+ P ++ P
Sbjct: 1058 --KDSVVEFPSPPSDSDFPPPPPETE--LPLPPIEIPAVFSGNTSPKVAVVNPQPQ---- 1109
Query: 1169 GRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPSPVPTPASPS 1221
+ S+ S +A PPT+P+ + S P M+ V P VPT S
Sbjct: 1110 -QWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQ---VPTSPKSS 1158
Score = 47.4 bits (111), Expect = 2e-04
Identities = 72/276 (26%), Positives = 96/276 (34%), Gaps = 80/276 (28%)
Query: 1806 PPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLAQPQASALAT 1865
P TA P+ P PP P P P PPPPPLP A SA
Sbjct: 618 PYTASQPSPPLPPPPPPPPPPPPP--------------PPPPPPPLPSQSAPSAGSAAPM 663
Query: 1866 -VKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQRQRL 1924
VK S I+ L + S H GA + P +Q Q
Sbjct: 664 FVKYSTITRLQNA--------------------------SQHSGALFKPPTPPVMQSQ-- 695
Query: 1925 SDDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGV-----SPTAAAAPGATSPSASSSSTS 1979
S + P + + P PP PP P G+ + +P A + P ++P
Sbjct: 696 ---SVKPQILVPPNGVVPPPPPPPPPPTP-GSAMAQLKPAPCAPSLPQFSAPPPPLKIHQ 751
Query: 1980 TRHLQGVEFEMRP-------PLLRRAPSPSLL----PASEHKVSP-----APRPSSLPIL 2023
+H+ V P PL +AP L+ P S V+P AP + P+
Sbjct: 752 VQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVP 811
Query: 2024 PS--GPLYPGLFDIRGSPTGGAGGSADPFAPVFVPP 2057
P+ P +P + I SP P PV VPP
Sbjct: 812 PAKKQPAFPASY-IPPSP---------PTPPVPVPP 837
Score = 46.2 bits (108), Expect = 3e-04
Identities = 87/373 (23%), Positives = 119/373 (31%), Gaps = 95/373 (25%)
Query: 1743 PGPPYPPQLMTPSKLRGRALGASGGLRP---------------GPSGGLRDPVTPTSPTV 1787
P PP PP P L ++ ++G P SG L P PT P +
Sbjct: 635 PPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKP--PTPPVM 692
Query: 1788 SVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPG-- 1845
L+ P GV V P PP P PT S +L P P
Sbjct: 693 QSQSVKPQILV--------PPNGV------VPPPPPPPPPPTPGSAMAQLKPAPCAPSLP 738
Query: 1846 -------------------------PPPPPLPGPLAQPQA--SALATVKASIISELSSKL 1878
PPPPP+P PL PQA L T+ A ++ + +
Sbjct: 739 QFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPL-PPQAPPKPLVTIPAPTSTKTVAPV 797
Query: 1879 QQFGGSSAAGGALPWARGGSGGGGDSHHGGASYVPER--TSSLQRQRLSDDSQSSLLSKP 1936
+P A+ ASY+P T + + Q S +KP
Sbjct: 798 VTQAAPPTPTPPVPPAK-------KQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKP 850
Query: 1937 -----------VSSLFQNWPKPPLPPLPTGTGVSPTAAAAPGATSPSASSS---STSTRH 1982
V + +P PP PP + P A + P+ + S+
Sbjct: 851 PPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIP 910
Query: 1983 LQGVEFEMRPP---LLRRAPSPSLLPASEHKVSPAPRPSSLPILPSGPLYPGLFDIRGSP 2039
+ +F PP L+ P PS +PA P P P + P PG + S
Sbjct: 911 VPSPDFPPPPPESSLVFPPPPPSPVPA-----PPPPPPPTASPTPDKSGSPGK---KTSK 962
Query: 2040 TGGAGGSADPFAP 2052
T GG P P
Sbjct: 963 TSSPGGKKPPPTP 975
Score = 31.6 bits (70), Expect = 8.8
Identities = 37/146 (25%), Positives = 52/146 (35%), Gaps = 17/146 (11%)
Query: 1915 RTSSLQRQRLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGVSPTAAAAPGATSPSAS 1974
R S+ R S S K V+ + P PPLPP P P P PS S
Sbjct: 594 RMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQS 653
Query: 1975 SSSTSTRHLQGVEFEMRPPLLRRAPSPSLLPASEHKVSPAPRPSSLPILPSGPLYPGLFD 2034
+ S + P ++ + L AS+H +P + P++ S + P +
Sbjct: 654 APSAGS---------AAPMFVKYSTITRLQNASQHS-GALFKPPTPPVMQSQSVKPQIL- 702
Query: 2035 IRGSPTGGAGGSADPFAPVFVPPHPG 2060
P G P P PP PG
Sbjct: 703 ---VPPNGVVPPPPPPPP---PPTPG 722
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 95.9 bits (237), Expect = 4e-19
Identities = 89/329 (27%), Positives = 113/329 (34%), Gaps = 48/329 (14%)
Query: 905 AMKFSRSLSVPGSEDIPPPPTTSPPE--------PPYSTPPVPSSSGRLTPSPRGGPFNP 956
A+ ++SL+ S++ P + PE P TPP P P G P
Sbjct: 12 ALSSAQSLNEDVSQEESPSVISGKPEGRRPQGGNQPQRTPPPPGK-------PEGRPPQG 64
Query: 957 GSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHH 1016
G+ P P +GP P G + P P P + PPP+P
Sbjct: 65 GNQSQGPPPRPGKPEGPPPQ----GGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKP 120
Query: 1017 HAHPPHPPEMETGGSPDDPPPRLAL--GPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGG 1074
PP + G PPPR GP P G + GP P PG P G GG
Sbjct: 121 EGPPP-----QGGNQSQGPPPRPGKPEGPPPQ-GGNQSQGPPPRPGKPE----GPPPQGG 170
Query: 1075 GSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTS 1134
SQGP PP P + G +GP + K EG P +GG P P
Sbjct: 171 NQSQGP-------PPHPGKPEG-PPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPR- 221
Query: 1135 PASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGG 1194
P P+ PP+ + P P G Q + PP P G G
Sbjct: 222 PGKPEGPPSQGGNKPQGPPPHPG--------KPQGPPPQEGNKPQRPPPPGRPQGPPPPG 273
Query: 1195 GSSPSPAPAMSPVPPSPSPVPTPASPSGP 1223
G+ P P + P P P P P P
Sbjct: 274 GNPQQPLPPPAGKPQGPPPPPQGGRPHRP 302
Score = 72.0 bits (175), Expect = 6e-12
Identities = 84/318 (26%), Positives = 103/318 (32%), Gaps = 79/318 (24%)
Query: 864 PHHRAQPSYERPSFLPPGPGLMLRQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPP 923
P R +P PP PG + G + P PP PG + PPP
Sbjct: 36 PEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGP---PPR---------PGKPEGPPP 83
Query: 924 PTTS-----PPEP--PYSTPPVPSSSGRLTP----SPRGGPFNPGSGGPLPASSPASFDG 972
+ PP P P PP + + P P G P G+ P P +G
Sbjct: 84 QGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEG 143
Query: 973 PSP--------PDTRVGSREKSLYHSGPLPPAHHH----PPHHHHHHAPPPQPHHHHAHP 1020
P P P R G E GP P + PPH PPPQ + P
Sbjct: 144 PPPQGGNQSQGPPPRPGKPE------GPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGP 197
Query: 1021 PHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGP 1080
P P G P+ PPP+ G + GP P PG P G GG QGP
Sbjct: 198 PPRP-----GKPEGPPPQ---------GGNQSQGPPPRPGKPE----GPPSQGGNKPQGP 239
Query: 1081 ALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGG----LPPA------- 1129
PP P + ++ P + +G P GG LPP
Sbjct: 240 -------PPHPGKPQGPPPQEGNKPQRPP--PPGRPQGPPPPGGNPQQPLPPPAGKPQGP 290
Query: 1130 PSPTSPASPQPPPAVAAP 1147
P P P PP P
Sbjct: 291 PPPPQGGRPHRPPQGQPP 308
Score = 69.7 bits (169), Expect = 3e-11
Identities = 84/308 (27%), Positives = 98/308 (31%), Gaps = 83/308 (26%)
Query: 1369 EGGGAPQ-PPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLG 1427
+GG Q PPPRP P E PPP + S PP P + E G G
Sbjct: 63 QGGNQSQGPPPRPGKP--EGPPPQGGNQSQ------------GPPPRPGKPE-GQPPQGG 107
Query: 1428 SQEKSLPASP-----PAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAP 1482
+Q + P P P + + PP PG E P P G P
Sbjct: 108 NQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGK--------PEGPPPQGGNQSQGPPPRP 159
Query: 1483 EEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGL 1542
+PE P P P GPP + G P PR P P ++ G
Sbjct: 160 GKPEGPPPQGGNQSQGPPPHP-GKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQG- 217
Query: 1543 PLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHP-LPDTPAPATP 1601
PPP P +P PP + N KP+ P PPHP P P P
Sbjct: 218 -----PPPRPG-----------KPEGPPSQGGN---KPQGP----PPHPGKPQGPPPQEG 254
Query: 1602 LPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAP 1661
P PP PP G P P G P P PA
Sbjct: 255 NKPQRPP-----PP-----------------------GRPQGPPPPGGNPQQPLPPPAGK 286
Query: 1662 QPGPDPPP 1669
GP PPP
Sbjct: 287 PQGPPPPP 294
Score = 56.2 bits (134), Expect = 3e-07
Identities = 91/399 (22%), Positives = 110/399 (27%), Gaps = 125/399 (31%)
Query: 1465 EPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPPP--- 1521
E P+ G + R +P+R P E P+ S PP P PPP
Sbjct: 27 ESPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGG 86
Query: 1522 SPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPE 1581
+ + PP P P G PPP P +P PP + N + P
Sbjct: 87 NQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPG-----------KPEGPPPQGGNQSQGP- 134
Query: 1582 SPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAA 1641
P PG P P + PP P PP QG + +
Sbjct: 135 -PPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPP--------------------QGGNQS 173
Query: 1642 PGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLS 1701
G P PG P P GP P PG G
Sbjct: 174 QGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEG--------------------------P 207
Query: 1702 AEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRA 1761
GG+ G G GP + GG+ GPP P
Sbjct: 208 PPQGGNQSQGPPPRPGKPEGPP------------SQGGNKPQGPPPHP------------ 243
Query: 1762 LGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPE 1821
G G P + P P P GPP G
Sbjct: 244 -GKPQGPPPQEGNKPQRPPPPGRP------------------QGPPPPGGN--------- 275
Query: 1822 VPPVPLPTASSLPRKLLPWEEGPGPPPPPLPG-PLAQPQ 1859
P PLP + P+ GPPPPP G P PQ
Sbjct: 276 -PQQPLPPPAGKPQ---------GPPPPPQGGRPHRPPQ 304
Score = 46.6 bits (109), Expect = 3e-04
Identities = 54/178 (30%), Positives = 67/178 (37%), Gaps = 37/178 (20%)
Query: 1369 EGGGAPQ-PPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLG 1427
+GG Q PPPRP P E PPP + S PP P + E G G
Sbjct: 147 QGGNQSQGPPPRPGKP--EGPPPQGGNQSQ------------GPPPHPGKPEGPPPQG-G 191
Query: 1428 SQEKSLPASP-----PAARRSLLHRLPPTAPGV--GPLLLQLGTEP--PAPHPGVSKPWR 1478
+Q + P P P + + PP PG GP Q G +P P PHPG +
Sbjct: 192 NQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPS-QGGNKPQGPPPHPGKPQGPP 250
Query: 1479 SAAPEEPERLPLHVRFLENCQPRAPVTSGRGP-----PSEDGPGVPPPSPRRSVPPSP 1531
+P+R P R P+ P G P P P PPP P+ P P
Sbjct: 251 PQEGNKPQRPPPPGR------PQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRP 302
Score = 36.2 bits (82), Expect = 0.36
Identities = 23/94 (24%), Positives = 33/94 (35%), Gaps = 12/94 (12%)
Query: 454 PGAASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQP 513
P P P G+Q Q P P P G + ++ + P +P
Sbjct: 178 PHPGKPEGPPPQGGNQSQGPPPRP------------GKPEGPPPQGGNQSQGPPPRPGKP 225
Query: 514 RGRPSSSGTPREGPAGGTGGSGGPGGSLGSRGRR 547
G PS G +GP G GP G++ +R
Sbjct: 226 EGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQR 259
Score = 33.5 bits (75), Expect = 2.3
Identities = 23/100 (23%), Positives = 32/100 (32%), Gaps = 9/100 (9%)
Query: 454 PGAASSGAPGPTSGSQGQSQPSAPTT---------KLSSGTLRSASSPRGARARSPSRGR 504
P P P G+Q Q P P S G P G + ++ +
Sbjct: 136 PRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQ 195
Query: 505 HPEDAKRQPRGRPSSSGTPREGPAGGTGGSGGPGGSLGSR 544
P +P G P G +GP G GP G++
Sbjct: 196 GPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNK 235
Score = 32.7 bits (73), Expect = 4.0
Identities = 22/93 (23%), Positives = 33/93 (35%), Gaps = 13/93 (13%)
Query: 454 PGAASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQP 513
P G P P G+Q Q P P P G + ++ + P +P
Sbjct: 53 PPGKPEGRP-PQGGNQSQGPPPRP------------GKPEGPPPQGGNQSQGPPPRPGKP 99
Query: 514 RGRPSSSGTPREGPAGGTGGSGGPGGSLGSRGR 546
G+P G +GP G GP G++ +
Sbjct: 100 EGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQ 132
Score = 32.7 bits (73), Expect = 4.0
Identities = 21/93 (22%), Positives = 31/93 (33%), Gaps = 12/93 (12%)
Query: 454 PGAASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQP 513
P P P G+Q Q P P P G + ++ + P +P
Sbjct: 73 PRPGKPEGPPPQGGNQSQGPPPRP------------GKPEGQPPQGGNQSQGPPPRPGKP 120
Query: 514 RGRPSSSGTPREGPAGGTGGSGGPGGSLGSRGR 546
G P G +GP G GP G++ +
Sbjct: 121 EGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQ 153
Score = 32.7 bits (73), Expect = 4.0
Identities = 21/93 (22%), Positives = 31/93 (33%), Gaps = 12/93 (12%)
Query: 454 PGAASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQP 513
P P P G+Q Q P P P G + ++ + P +P
Sbjct: 115 PRPGKPEGPPPQGGNQSQGPPPRP------------GKPEGPPPQGGNQSQGPPPRPGKP 162
Query: 514 RGRPSSSGTPREGPAGGTGGSGGPGGSLGSRGR 546
G P G +GP G GP G++ +
Sbjct: 163 EGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQ 195
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 95.5 bits (236), Expect = 5e-19
Identities = 117/434 (26%), Positives = 143/434 (32%), Gaps = 71/434 (16%)
Query: 826 LAAAQ---QTISASESPG-----PGGLASLGKHRPKGFFATESSFDPHHRAQPSYERPSF 877
L++AQ + +S ESP P G G ++P+G P +P
Sbjct: 13 LSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQG--PPSPPGKPQGPPPQGGNQPQG 70
Query: 878 LPPGPGLMLR------QKSIGAAEDDRPYLAPPAMKFSRS-LSVPGSEDIPPPPTTSPPE 930
PP PG K G +P PP SRS S PG PPP + P+
Sbjct: 71 PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQ 130
Query: 931 PPYSTPPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSLYHS 990
P P P P P+GG N G P P GP P G + S
Sbjct: 131 GPPPPPGKPQG-----PPPQGG--NKPQGPPPPGKP----QGPPPQ----GDNKSRSSRS 175
Query: 991 GPLPPAHHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETG----GSPDDPPPR-------- 1038
P P P + PPP P PP G G P PPP+
Sbjct: 176 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSA 235
Query: 1039 -----LALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAAS 1093
GP P G + GP P PG P G GG QGP PP
Sbjct: 236 RSPPGKPQGPPPQ-GGNQPQGPPPPPGKPQ----GPPPQGGNKPQGPP------PPGKPQ 284
Query: 1094 AAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSI 1153
P + G + K +G P +GG P P P P PQ PP +
Sbjct: 285 GP---PPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPP-PGKPQGPPPQGGNKPQGPP 340
Query: 1154 PIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPE------PTGGGGGGGSSPSPAPAMSPV 1207
P P S RS++ + + P Q E P GG P PA P
Sbjct: 341 PPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQ 400
Query: 1208 -PPSPSPVPTPASP 1220
PP P P+ P
Sbjct: 401 GPPRPPQGGRPSRP 414
Score = 87.8 bits (216), Expect = 1e-16
Identities = 97/357 (27%), Positives = 120/357 (33%), Gaps = 57/357 (15%)
Query: 909 SRSLSVPGSEDIPPP---PTTSPPEPPY---STPPVPSSSGRLTPSPRGGPFNP---GSG 959
S SL + PP PP PP PP + + P P G P P G
Sbjct: 28 SPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 87
Query: 960 GPLPASSPASFDGPSPP-DTRVGSREKSLYHSGPLPPAHHH----PPHHHHHHAPPPQPH 1014
P P GP P D R GP P + PP PPPQ
Sbjct: 88 KPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 147
Query: 1015 HHHAHPP-------HPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHH 1067
+ PP PP+ + PP GP P G + GP P PG P
Sbjct: 148 NKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQ-GGNQPQGPPPPPGKP----Q 202
Query: 1068 GSAGGGGGSSQGPAL--RYFQLPPRAASAAMYV----------PARSGRGRKGPLVKQTK 1115
G GG QGP + PP+ + + P + G +GP K
Sbjct: 203 GPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGK 262
Query: 1116 VEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGS 1175
+G P +GG P P P P PQ PP ++S ++P G QG
Sbjct: 263 PQGPPPQGGNKPQGPPP--PGKPQGPPPQGGSKSRSS--------RSPPGKPQGPPPQGG 312
Query: 1176 STEAEPPTQP-EPTGGGGGGGSSP-SPAPAMSPVPPSP-------SPVPTPASPSGP 1223
+ PP P +P G GG+ P P P P P P S P P GP
Sbjct: 313 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGP 369
Score = 87.8 bits (216), Expect = 1e-16
Identities = 92/344 (26%), Positives = 112/344 (32%), Gaps = 68/344 (19%)
Query: 915 PGSEDIPPPPTTSPPE--PPYSTPPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDG 972
PG PPP + P+ PP P P G + SPR P P P + P G
Sbjct: 75 PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP---QG 131
Query: 973 PSPPDTRVGSREKSLYHSGPLPPAHHHP---PHHHHHHAPPPQPHHHHAHPPHPPEMETG 1029
P PP + GP P + P P PPPQ + PP
Sbjct: 132 PPPPPGKP---------QGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPP----- 177
Query: 1030 GSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPAL--RYFQL 1087
G P PPP+ PQ GP P PG P G GG QGP +
Sbjct: 178 GKPQGPPPQGGNQPQ---------GPPPPPGKPQ----GPPPQGGNKPQGPPPPGKPQGP 224
Query: 1088 PPRAASAAMYV----------PARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPAS 1137
PP+ + + P + G +GP K +G P +GG P P P P
Sbjct: 225 PPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP--PGK 282
Query: 1138 PQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGG------ 1191
PQ PP ++S P P G QG P P P GG
Sbjct: 283 PQGPPPQGGSKSRSSRSPPGKPQGPPP--QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 340
Query: 1192 -----------GGGGSSPSPAPAMSPVPPSPSPVPTPASPSGPA 1224
GG S + +P P P P P PA
Sbjct: 341 PPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPA 384
Score = 82.8 bits (203), Expect = 3e-15
Identities = 112/417 (26%), Positives = 142/417 (34%), Gaps = 74/417 (17%)
Query: 1369 EGGGAPQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGS 1428
+GG PQ PP PP + + PPP ++P PP P + G G+
Sbjct: 42 QGGNKPQGPPSPPG-KPQGPPP-------QGGNQP------QGPPPPPGKPQGPPPQGGN 87
Query: 1429 QEKSLP------ASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHP----------- 1471
+ + P PP +S R PP P P Q G +P P P
Sbjct: 88 KPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPP--QGGNQPQGPPPPPGKPQGPPPQ 145
Query: 1472 GVSKPWRSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPPSEDG--PGVPPPSPRRSVPP 1529
G +KP P +P+ P ++ R+P +GPP + G P PPP P + P
Sbjct: 146 GGNKPQGPPPPGKPQGPPPQGDN-KSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 204
Query: 1530 SP---TSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTP 1586
P P+ G P PPP + +P PP + N P P
Sbjct: 205 PPQGGNKPQGPPPPGKPQG--PPPQGDNKSQSARSPPGKPQGPPPQGGNQ------PQGP 256
Query: 1587 GPPHPLPDTPAPA---TPLPPVPPPAVAAAPPTLDSTASSLTSYDSEV-ATLTQGASAAP 1642
PP P P P P P PP PP S + S S + QG +
Sbjct: 257 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQ 316
Query: 1643 GDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVD---SRSSSDHPLETISSASTLSS 1699
G P PPG P P GP PPPG G SRS+ P
Sbjct: 317 GPPPPPGKPQGPPPQGGNKPQGP-PPPGKPQGPPPQGGSKSRSARSPP------GKPQGP 369
Query: 1700 LSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSK 1756
EG G AG P+ QA GPP PPQ PS+
Sbjct: 370 PQQEGNNPQGPPPPAGGN----PQ---------QPQAPPAGQPQGPPRPPQGGRPSR 413
Score = 80.5 bits (197), Expect = 2e-14
Identities = 103/371 (27%), Positives = 121/371 (32%), Gaps = 37/371 (9%)
Query: 1500 PRAPVTSGRGPPSEDG--PGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVE 1557
P +P +GPP + G P PPP P + P P ++ G P PP P
Sbjct: 50 PPSPPGKPQGPPPQGGNQPQGPPPPPGK--PQGPPPQGGNKPQGPP----PPGKPQGPPP 103
Query: 1558 DGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPA---TPLPPVPPPAVAAAP 1614
G+ PP + P P PP P P P P P PP P
Sbjct: 104 QGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP 163
Query: 1615 PTLDSTASSLTSYDSEV-ATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDS 1673
P D+ + S S + QG + G P PPG P P GP PPPG
Sbjct: 164 PQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP-PPPGKPQ 222
Query: 1674 GIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLD 1733
G D+ ++ S GG+ G G GP
Sbjct: 223 G-----PPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG------- 270
Query: 1734 GQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAG 1793
G G PG P P SK R P P GG P P P G
Sbjct: 271 GNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGG-NQPQGPPPPPGKPQGPP 329
Query: 1794 TDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLL--PWEEGPGP--PPP 1849
G GPP G GP P +A S P K P +EG P PPP
Sbjct: 330 PQGG---NKPQGPPPPGKPQGP----PPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPP 382
Query: 1850 PLPGPLAQPQA 1860
P G QPQA
Sbjct: 383 PAGGNPQQPQA 393
Score = 62.8 bits (151), Expect = 4e-09
Identities = 96/374 (25%), Positives = 110/374 (29%), Gaps = 99/374 (26%)
Query: 1502 APVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEF 1561
AP G P GP PP P+ P P+ PPP P
Sbjct: 39 APPQGGNKP---QGPPSPPGKPQGPPPQGGNQPQG-----------PPPPPG-------- 76
Query: 1562 LFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTA 1621
+P PP + N KP+ P PG P P P P PP PP
Sbjct: 77 ---KPQGPPPQGGN---KPQGPPPPGKPQGPP--PQGDKSRSPRSPPGKPQGPPP----- 123
Query: 1622 SSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIE---EV 1678
QG + G P PPG P P GP PPPG G +
Sbjct: 124 --------------QGGNQPQGPPPPPGKPQGPPPQGGNKPQGP-PPPGKPQGPPPQGDN 168
Query: 1679 DSRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFG 1738
SRSS P + GG+ G G GP G
Sbjct: 169 KSRSSRSPPGKPQGPPPQ--------GGNQPQGPPPPPGKPQGP------------PPQG 208
Query: 1739 GSSTPGPPYPPQLMTPSKLRGRALGASGGLRPG-----PSGGLRDPVTPTSPTVSVTGAG 1793
G+ GPP P + P +G S PG P G P P P G
Sbjct: 209 GNKPQGPPPPGKPQGPPP-QGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 267
Query: 1794 TDGLLALRACSGPPTAGVAGGP----------VAVEPEVPPVPLPTASSLPRKLLPWEEG 1843
G GPP G GP P P P P + P +G
Sbjct: 268 PQG---GNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQP-------QG 317
Query: 1844 PGPPPPPLPGPLAQ 1857
P PPP GP Q
Sbjct: 318 PPPPPGKPQGPPPQ 331
Score = 60.1 bits (144), Expect = 2e-08
Identities = 80/320 (25%), Positives = 95/320 (29%), Gaps = 96/320 (30%)
Query: 1365 KESSEGGGAPQPPPRPPSPRYEAPPP---TPHHHSPHAHHEPVLRLWGASPPDPARRELG 1421
+ S G PQ PP + + PPP P P ++P PP P +
Sbjct: 171 RSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP------QGPPPPGK---- 220
Query: 1422 YRAGLGSQEKSLPASPP--AARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRS 1479
P PP +S R PP P P Q G +P P P KP
Sbjct: 221 ------------PQGPPPQGDNKSQSARSPPGKPQGPP--PQGGNQPQGPPPPPGKP--- 263
Query: 1480 AAPEEPERLPLHVRFLENCQPRAPVTSGRGPPSEDG---PGVPPPSPRRSVPPSPTSPRA 1536
+GPP + G G PPP + PP S
Sbjct: 264 ----------------------------QGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSR 295
Query: 1537 SEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTP 1596
S + PP P PPP + P P PP P P
Sbjct: 296 SSRS-------PPGKPQG-------------PPP-------QGGNQPQGPPPPPGKPQGP 328
Query: 1597 APA---TPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPP---GP 1650
P P P PP PP S + S S + Q P P PP P
Sbjct: 329 PPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNP 388
Query: 1651 PAPAAPAPAAPQPGPDPPPG 1670
P AP PQ P PP G
Sbjct: 389 QQPQAPPAGQPQGPPRPPQG 408
Score = 55.5 bits (132), Expect = 6e-07
Identities = 64/240 (26%), Positives = 78/240 (32%), Gaps = 27/240 (11%)
Query: 839 PGPGGLASLGKHRPKGFFATESSFDPHHRAQPSYERPSFLPPGPGLMLRQKSIGAAEDDR 898
P GG G P G P +P P P GP KS A
Sbjct: 184 PPQGGNQPQGPPPPPG---KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPG 240
Query: 899 PYLAPPAMKFSRSLSVP---GSEDIPPPPTTS------PPEPPYSTPPVPSSSGRLTPSP 949
PP ++ P G PPP + PP P PP S R + SP
Sbjct: 241 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSP 300
Query: 950 RGGPFNPG-SGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPP------H 1002
G P P GG P P P P + G++ + GP PP P
Sbjct: 301 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ-----GPPPPGKPQGPPPQGGSK 355
Query: 1003 HHHHHAPPPQPH---HHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTP 1059
+PP +P + P P GG+P P A PQ R +GG PS P
Sbjct: 356 SRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 415
Score = 33.5 bits (75), Expect = 2.3
Identities = 34/128 (26%), Positives = 42/128 (32%), Gaps = 18/128 (14%)
Query: 414 PKYAARRRGPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQSQ 473
P+ + +GPP G P N S P PG P P G+Q Q
Sbjct: 144 PQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSP-------PGKPQG--PPPQGGNQPQGP 194
Query: 474 PSAPTTKLS----SGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPREGPAG 529
P P G P G P +G + + R P G+P G P P G
Sbjct: 195 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQ--GPP---PQG 249
Query: 530 GTGGSGGP 537
G G P
Sbjct: 250 GNQPQGPP 257
Score = 33.5 bits (75), Expect = 2.3
Identities = 32/139 (23%), Positives = 45/139 (32%), Gaps = 17/139 (12%)
Query: 414 PKYAARRRGPPGTGLTVPPALLRANSDTSMALPDWMVFSAP--GAASSGAPGPTSGS--- 468
P+ + +GPP G P N S P P G P P G
Sbjct: 206 PQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 265
Query: 469 ---QGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPRE 525
QG ++P P P+G + S+ R +P+G P G +
Sbjct: 266 PPPQGGNKPQGPPPP---------GKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQ 316
Query: 526 GPAGGTGGSGGPGGSLGSR 544
GP G GP G++
Sbjct: 317 GPPPPPGKPQGPPPQGGNK 335
Score = 32.7 bits (73), Expect = 4.0
Identities = 27/100 (27%), Positives = 34/100 (34%), Gaps = 9/100 (9%)
Query: 452 SAPGAASSGAPGPTSGSQGQSQPSAPTTKLS----SGTLRSASSPRGARARSPSRG---R 504
S PG P P G+Q Q P P G P G P +G R
Sbjct: 52 SPPGKPQG--PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSR 109
Query: 505 HPEDAKRQPRGRPSSSGTPREGPAGGTGGSGGPGGSLGSR 544
P +P+G P G +GP G GP G++
Sbjct: 110 SPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 149
Score = 32.0 bits (71), Expect = 6.8
Identities = 29/129 (22%), Positives = 42/129 (32%), Gaps = 17/129 (13%)
Query: 414 PKYAARRRGPPGTGLTVPPALLRANSDTSMALPDWMVFSAP--GAASSGAPGPTSGS--- 468
P+ + +GPP G P + S P P G P P G
Sbjct: 268 PQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 327
Query: 469 ---QGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPRE 525
QG ++P P P+G + S+ R +P+G P G +
Sbjct: 328 PPPQGGNKPQGPPPP---------GKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQ 378
Query: 526 GPAGGTGGS 534
GP GG+
Sbjct: 379 GPPPPAGGN 387
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 95.1 bits (235), Expect = 6e-19
Identities = 113/408 (27%), Positives = 144/408 (35%), Gaps = 58/408 (14%)
Query: 1637 GASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPG----TDSGIEEVDSRSSSDHPLETIS 1692
G G P PAAPA AP P+PPP G + S PL
Sbjct: 59 GNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAG 118
Query: 1693 SASTLSSLSAEGGGSAGGGG--GAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQ 1750
A + L GSAG A A VA+GPE P P P +
Sbjct: 119 PAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPE-------------------PAPAGPAK 159
Query: 1751 LMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAG 1810
P+ L RA G G PGP G P P P + T G+ LL + P +
Sbjct: 160 PAGPAALAARA-GPGPGPGPGPGPG-PGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSL 217
Query: 1811 VAGGPVAVEP-----------EVPPV------PLPTASSLPRKLLPWEEGPG-PPPPPLP 1852
V GP A+ P + PP P P A S P P PPPPP P
Sbjct: 218 VNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAP 277
Query: 1853 GPLAQPQASALATVKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYV 1912
LA+P A+ + Q G + AA P A G +G G G A+
Sbjct: 278 ATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAA 337
Query: 1913 PE---RTSSLQR--QRLSDDSQSSLLSKPVSSLFQNWPKPPLP-PLPTGTGVSPTAAAAP 1966
P + S +R Q +Q+ S P S+ P + LP+ V P A P
Sbjct: 338 PAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTP 397
Query: 1967 ------GATSPSASSSSTSTRHLQGVEFEMRPPLLR-RAPSPSLLPAS 2007
A + + S S T T G+ + P +L R P P P +
Sbjct: 398 TGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTN 445
Score = 77.8 bits (190), Expect = 1e-13
Identities = 91/332 (27%), Positives = 110/332 (33%), Gaps = 56/332 (16%)
Query: 937 PVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPA 996
P + G P G PG GGP P PP R + L +GP PPA
Sbjct: 78 PAEGAPGAAPEPPPAGRARPGGGGP---------QRPGPPSPR-----RPLVPAGPAPPA 123
Query: 997 HHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQP-SLRGWRGGGP 1055
P PP A P + G P P GP + R G GP
Sbjct: 124 AKLRP-------PPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGP 176
Query: 1056 SPTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQ-- 1113
P PG P P AG G + + AA A V +G PL K
Sbjct: 177 GPGPG-PGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLV--NNGPAALLPLPKPAA 233
Query: 1114 --TKVEGEPQKGGGLPPAPSPTSPAS-------------PQPPPAVAAPSEKNSIPIPTI 1158
T ++ P G PPAP+ SP + P P PA A + PT
Sbjct: 234 PGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPT- 292
Query: 1159 IIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVP----PSPSPV 1214
AP+ + G S A P P G G G A A +P P SP V
Sbjct: 293 --AAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRV 350
Query: 1215 PTPASP-------SGPATLDFTSQFGAALVGA 1239
A P SGPA+ + G + GA
Sbjct: 351 VQAAPPAAQTLAASGPASTAASMVIGPTMQGA 382
Score = 76.3 bits (186), Expect = 3e-13
Identities = 192/866 (22%), Positives = 266/866 (30%), Gaps = 197/866 (22%)
Query: 1116 VEGEPQKGGGL-PPAPSPTSP-ASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQ 1173
V G P G P AP+ +P A+P+PPPA A P S R
Sbjct: 63 VSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPG--------PPSPRRPL 114
Query: 1174 GSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPSPVPTPASPSGPATLDFTSQFG 1233
+ A P + P G G +P PA A P P+P PA P+GPA L
Sbjct: 115 VPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAG-PAKPAGPAAL------- 166
Query: 1234 AALVGAARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMF 1293
AAR G G G PGP
Sbjct: 167 -----AAR----------------------------AGPGPGPGPGP------------- 180
Query: 1294 SAEPYLRLESAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPASPL 1353
G G G G A G ++ S P V + PA+ L
Sbjct: 181 -----------GPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNN---GPAALL 226
Query: 1354 GLALAARERALKESSEGGGAPQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPP 1413
L A + ++ GA PP +P +PP P +P A P PP
Sbjct: 227 PLPKPAAPGTVIQTPPFVGAAAPP----APAAPSPPAAPAPAAPAAAPPP-------PPP 275
Query: 1414 DPAR--RELGYRAGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHP 1471
PA R G+ AG + ++P A P AP G G P P
Sbjct: 276 APATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQ--PGPGA 333
Query: 1472 GVSKPWRSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPPSED-----GP---------- 1516
+ P E P+R+ ++ P A + GP S GP
Sbjct: 334 AAAAPAPGVKAESPKRV------VQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPA 387
Query: 1517 GVPPPSP-----------------------------RRSVPPSPTSPRASEENGLPLLV- 1546
VPPP+P R ++ P+ +PR + P +
Sbjct: 388 AVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQ 447
Query: 1547 ---LPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLP 1603
LPP V E+G+ L + + + +P++ + P P P P + +
Sbjct: 448 NFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQ 507
Query: 1604 PVPPPAVA--AAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAP 1661
P +A P T+ S + ATL + P G A A A
Sbjct: 508 APGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQP--QLVLGGAAQTASLGTAT 565
Query: 1662 QPGPDPPPGTDSGIEEVDSRSSSDHPLETISSA----STLSSLSAEGGGSAGGGGGAGAG 1717
P T G + S++ +E + STL L++ G S
Sbjct: 566 AVQTGTPQRTVPGA--TTTSSAATETMENVKKCKNFLSTLIKLASSGKQSTETAANVKEL 623
Query: 1718 VAS---------------GPELLDTYVAYL----------------DGQAFGGSSTPGPP 1746
V + EL + YL D AF S PP
Sbjct: 624 VQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQQQPP 683
Query: 1747 YPPQLMTPSKLRGRALGAS-----GGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALR 1801
PP + L L +S G + L+ PV + V G G G
Sbjct: 684 -PPTSQATTALTAVVLSSSVQRTAGKTAATVTSALQPPVLSLTQPTQV-GVGKQGQPTPL 741
Query: 1802 ACSGPPTAGVAGGPVAVE-PEVPPVPLPTASSLPRKLLPWEEGPGP-PPPPLPGPLAQPQ 1859
PP G P V + P V L + P + P P P+ P P
Sbjct: 742 VIQQPPKPGALIRPPQVTLTQTPMVALRQPHNRIMLTTPQQIQLNPLQPVPVVKPAVLPG 801
Query: 1860 ASALATVKASIISELSSKLQQFGGSS 1885
AL+ V A + +KL++ GG S
Sbjct: 802 TKALSAVSAQAAAAQKNKLKEPGGGS 827
Score = 72.8 bits (177), Expect = 3e-12
Identities = 84/310 (27%), Positives = 105/310 (33%), Gaps = 66/310 (21%)
Query: 921 PPPPTTSPPEPPYSTPPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRV 980
P PP G PG GGP P PP R
Sbjct: 87 PEPPPA-------------------------GRARPGGGGP---------QRPGPPSPR- 111
Query: 981 GSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLA 1040
+ L +GP PPA P PP A P + G P P
Sbjct: 112 ----RPLVPAGPAPPAAKLRP-------PPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKP 160
Query: 1041 LGPQPSLRGWRGGGPSPTPG-APSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVP 1099
GP +L G GP P PG P P AG G + + AA A V
Sbjct: 161 AGP-AALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLV- 218
Query: 1100 ARSGRGRKGPLVKQ----TKVEGEPQKGGGLPPAP-SPTSPASPQPPPAVAAPSEKNSIP 1154
+G PL K T ++ P G PPAP +P+ PA+P P AAP P
Sbjct: 219 -NNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPP--P 275
Query: 1155 IPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAM---SPVPPSP 1211
P + + P + G T A P GG G++P+PAPA + V P
Sbjct: 276 APATLARPPGHPA------GPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQP 329
Query: 1212 SPVPTPASPS 1221
P A+P+
Sbjct: 330 GPGAAAAAPA 339
Score = 69.3 bits (168), Expect = 4e-11
Identities = 111/431 (25%), Positives = 152/431 (35%), Gaps = 61/431 (14%)
Query: 1004 HHHHAPPPQPH---------HHHAHPPHPPEMETGG--SPDDPPPRLALGPQPSLRGWRG 1052
HHHH P P +H P G +P + P A P P+ R G
Sbjct: 39 HHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPG 98
Query: 1053 GGPSPTPGAPSPSHHGSAGGGGGSS-------QGPALRYFQLPPRAASAAMYVPARSGRG 1105
GG PG PSP G + +G A +P AA AA PA +G
Sbjct: 99 GGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPA 158
Query: 1106 R-KGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAV------------AAPSEKNS 1152
+ GP + P G G P P P PA P + AAP+
Sbjct: 159 KPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLV 218
Query: 1153 IPIPTIIIKAPSTSSSGRSSQGSS--TEAEPPTQPEPTGGGGGGGSSPSP-APAMSPVPP 1209
P ++ P ++ G Q A PP P+ ++P+P APA +P PP
Sbjct: 219 NNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPS-----PPAAPAPAAPAAAPPPP 273
Query: 1210 SPSPVP---TPASPSGPATLDFTSQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDED 1266
P+P P P+GP T A AA + GG A + AG
Sbjct: 274 PPAPATLARPPGHPAGPPT-----AAPAVPPPAAAQNGGSAGAAPAPAPA-----AGGPA 323
Query: 1267 GGDGGLGTG---AAPGPRLRHSKSIDEGMFSAEPYLR-LESAGSGAGYGGYGAGSRAYGG 1322
G G G G AAP P ++ ++S + +A P + L ++G + G G
Sbjct: 324 GVSGQPGPGAAAAAPAPGVK-AESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGA 382
Query: 1323 GGGSSAFTSFLPPRPLVHP--LTGKALDPASPLGLALAARERA-LKESSEGGGAPQPPPR 1379
+A P P P G S A + RA L + PQPP
Sbjct: 383 LPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQN 442
Query: 1380 PPS-PRYEAPP 1389
P + ++ PP
Sbjct: 443 PTNIQNFQLPP 453
Score = 69.3 bits (168), Expect = 4e-11
Identities = 105/392 (26%), Positives = 141/392 (35%), Gaps = 51/392 (13%)
Query: 1700 LSAEGGGSAGGGGGAGAGVASG--PELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKL 1757
+S G+AG G A A A G PE A G GG PGPP P + + P+
Sbjct: 63 VSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGG---GGPQRPGPPSPRRPLVPA-- 117
Query: 1758 RGRALGASGGLRPGPSG--GLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAGVA--G 1813
G A A+ LRP P G G PV P + AG + P AG A
Sbjct: 118 -GPAPPAAK-LRPPPEGSAGSCAPV----PAAAAVAAGPE----------PAPAGPAKPA 161
Query: 1814 GPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLAQPQASALATVKASIISE 1873
GP A+ P P P GPGP P P PG A P A+ A++++
Sbjct: 162 GPAALAARAGPGPGP--------------GPGPGPGPGPGKPAGPGAAQTLNGSAALLNS 207
Query: 1874 LSSKLQQFGGSSAAGGAL-----PWARGGSGGGGDSHHGGASYVPERTSSLQRQRLSDDS 1928
+ + AL P A G A P S + +
Sbjct: 208 HHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPA 267
Query: 1929 QSSLLSKPVSSLFQNWPKPPLPPLPTGTGVSPTAAAAPGATSPSASSSSTSTRHLQGVEF 1988
+ P + P P P V P AAA G ++ +A + + + GV
Sbjct: 268 AAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSG 327
Query: 1989 EMRPPLLRRAPSPSLLPASEHKVSPAPRPSSLPILPSGPLYPGLFDIRGSPTGGAGGSAD 2048
+ P AP+P + S +V A P++ + SGP + G G A
Sbjct: 328 QPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQG----AL 383
Query: 2049 PFAPVFVPPHPGISGGL-GGALSGASRSLSPT 2079
P PP PG GL GA ++SLS T
Sbjct: 384 PSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRT 415
Score = 64.7 bits (156), Expect = 9e-10
Identities = 119/517 (23%), Positives = 169/517 (32%), Gaps = 110/517 (21%)
Query: 770 APQQAKRLPPPTISLRSKSMTSELEEMEYEQQPAPVPSMEKKRTVYQMALNKLDEILAAA 829
AP AK PPP S S + + +PAP + AA
Sbjct: 120 APPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGP-------------AAL 166
Query: 830 QQTISASESPGPGGLASLGKHRPKGFFATESS------FDPHHRAQPSYERPSFLPPGPG 883
PGPG G +P G A ++ + HH A P+ S + GP
Sbjct: 167 AARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAV---SLVNNGPA 223
Query: 884 LML---RQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPVPS 940
+L + + G P++ A P + P PP P P + PP P
Sbjct: 224 ALLPLPKPAAPGTVIQTPPFVGAAA---------PPAPAAPSPPAAPAPAAPAAAPPPPP 274
Query: 941 SSGRLTPSPRGGPFNP----------------GSGGPLPASSPASFDGPSPPDTRVGSRE 984
+ P G P P GS G PA +PA+ GP+ + G
Sbjct: 275 PAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAA-GGPAGVSGQPGPGA 333
Query: 985 KSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQ 1044
+ + P P P APP + P T S P P
Sbjct: 334 AA---AAPAPGVKAESPKRVVQAAPPAAQTLAASGP-----ASTAASMVIGPTMQGALPS 385
Query: 1045 PSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGS---------------------------- 1076
P+ P P PG P+ G+AG S
Sbjct: 386 PA------AVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQP 439
Query: 1077 SQGPA-LRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSP 1135
Q P ++ FQLPP + V + +G+ P +++ + AP P +P
Sbjct: 440 PQNPTNIQNFQLPP----GMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATP 495
Query: 1136 ASPQPPPAVAAPSEKNSIPI------PTIIIKAPSTSSSGRSSQGSST-EAEPPTQPEPT 1188
S PP + + PI PT IIK S + + Q S+T + P QP+
Sbjct: 496 TS--APPVQISTVQAPGTPIIARQVTPTTIIK--QVSQAQTTVQPSATLQRSPGVQPQLV 551
Query: 1189 GGGGGGGSSPSPAPAMSPVPPSPSPVPTPASPSGPAT 1225
GG +S A A+ P + VP + S AT
Sbjct: 552 LGGAAQTASLGTATAVQTGTPQRT-VPGATTTSSAAT 587
Score = 34.3 bits (77), Expect = 1.4
Identities = 36/141 (25%), Positives = 52/141 (36%), Gaps = 8/141 (5%)
Query: 1960 PTAAAAPGATSPSASSSSTSTRHLQGV-----EFEMRPPLLRRAPSPSLLPASEHKVSPA 2014
P A PG P + R L ++RPP A S + +PA+ V+
Sbjct: 91 PAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAA-AVAAG 149
Query: 2015 PRPSSLPILPSGPLYPGLFDIRGSPTGGAGGSADPFAPVFVPPHPGISGGLGGALSGASR 2074
P P+ P P+ P P R P G G P P PG + L G+ + +
Sbjct: 150 PEPA--PAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNS 207
Query: 2075 SLSPTRLLSLPPDKPFGAKPL 2095
+ +SL + P PL
Sbjct: 208 HHAAAPAVSLVNNGPAALLPL 228
Score = 32.3 bits (72), Expect = 5.2
Identities = 37/149 (24%), Positives = 52/149 (34%), Gaps = 18/149 (12%)
Query: 409 PFQESPKYAARRRGPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGS 468
P SP A P PPA ++A P + P A+ P P +
Sbjct: 252 PAAPSPPAAPAPAAPAAAPPPPPPA------PATLARPPGHP-AGPPTAAPAVPPPAAAQ 304
Query: 469 QGQSQPSAPTTKLSSGTLRSASSP--RGARARSPSRGRHPEDAKRQPRGRPSSSGTPREG 526
G S +AP ++G S GA A +P+ G E KR + P
Sbjct: 305 NGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAP--------- 355
Query: 527 PAGGTGGSGGPGGSLGSRGRRRKLYSAVP 555
PA T + GP + S + A+P
Sbjct: 356 PAAQTLAASGPASTAASMVIGPTMQGALP 384
Score = 32.0 bits (71), Expect = 6.8
Identities = 30/116 (25%), Positives = 41/116 (35%), Gaps = 17/116 (14%)
Query: 422 GPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQG----------- 470
GPP VPP N ++ A P + A SG PGP + +
Sbjct: 289 GPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPK 348
Query: 471 ---QSQPSAPTTKLSSGTLRSASS---PRGARARSPSRGRHPEDAKRQPRGRPSSS 520
Q+ P A T +SG +A+S + PS P A P G P +
Sbjct: 349 RVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGA 404
>gi|68131557 ankyrin repeat domain 28 [Homo sapiens]
Length = 1053
Score = 94.4 bits (233), Expect = 1e-18
Identities = 76/248 (30%), Positives = 114/248 (45%), Gaps = 17/248 (6%)
Query: 190 GTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMT 249
G SD +LL G D + D D G T L AA G++E + L GA + + + G +
Sbjct: 383 GFSDCCRKLLSSGFDIDTPD-DFGRTCLHAAA-AGGNLECLNLLLNTGADFNKKDKFGRS 440
Query: 250 ALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGI 309
LH AA + L AL+ G S N D RG TPL + A D +C E LL N A GI
Sbjct: 441 PLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGI 500
Query: 310 ADENGWQEIHQACQRGHSQHLE--------HLLFYGAEPGAQNASGNTA----LHICALY 357
D+ G+ +H + GH L+ +L + + S N A LH+ A +
Sbjct: 501 RDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYH 560
Query: 358 NKETCARILLYRGADKDVKNNNGQTPFQVAVIAGNFELGELIRNHREQDVVP---FQESP 414
+L+ D DV+N++G+TP +A G+ E +++ N +V + +P
Sbjct: 561 GHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTP 620
Query: 415 KYAARRRG 422
+AA G
Sbjct: 621 IHAAATNG 628
Score = 89.7 bits (221), Expect = 3e-17
Identities = 70/213 (32%), Positives = 99/213 (46%), Gaps = 4/213 (1%)
Query: 190 GTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMT 249
G V LLD G+D N ++ G TPL +A G V+ L GA ++ + G T
Sbjct: 217 GMISVVKYLLDLGVDMNEPNA-YGNTPLHVACYN-GQDVVVNELIDCGAIVNQKNEKGFT 274
Query: 250 ALHKAACARH-CLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLG 308
LH AA + H L L L+ G N K + G TPL TA+ G R + ++ + A +
Sbjct: 275 PLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRS-QTIIQSGAVID 333
Query: 309 IADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILLY 368
D+NG +H A + GH + L+ GA+ + G LH+ AL C R LL
Sbjct: 334 CEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLS 393
Query: 369 RGADKDVKNNNGQTPFQVAVIAGNFELGELIRN 401
G D D ++ G+T A GN E L+ N
Sbjct: 394 SGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLN 426
Score = 84.0 bits (206), Expect = 1e-15
Identities = 59/202 (29%), Positives = 92/202 (45%), Gaps = 3/202 (1%)
Query: 190 GTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMT 249
G D+V L+ K D N+ D++ TPL AA G E+I L L GA ++ + +T
Sbjct: 19 GDPDEVRALIFKKEDVNFQDNEK-RTPLHAAAYL-GDAEIIELLILSGARVNAKDSKWLT 76
Query: 250 ALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGI 309
LH+A + A+ LL N +D+ TPL H A +C E L+ + + +
Sbjct: 77 PLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPL-HIAAANKAVKCAEALVPLLSNVNV 135
Query: 310 ADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILLYR 369
+D G +H A GH + ++ LL GA A + A+H A ++L+
Sbjct: 136 SDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSH 195
Query: 370 GADKDVKNNNGQTPFQVAVIAG 391
GA+ K+ TP A +G
Sbjct: 196 GAEVTCKDKKSYTPLHAAASSG 217
Score = 82.4 bits (202), Expect = 4e-15
Identities = 58/203 (28%), Positives = 91/203 (44%), Gaps = 2/203 (0%)
Query: 189 LGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGM 248
+G + V L+ G + D S TPL AA + G + V++ L G ++ G
Sbjct: 183 MGHIEVVKLLVSHGAEVTCKDKKS-YTPLHAAASS-GMISVVKYLLDLGVDMNEPNAYGN 240
Query: 249 TALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLG 308
T LH A + + L+D G N K+ +G TPL A C ELL+ N A +
Sbjct: 241 TPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVN 300
Query: 309 IADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILLY 368
+ ++G +H G + ++ GA ++ +GNT LHI A Y E L+
Sbjct: 301 MKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLIT 360
Query: 369 RGADKDVKNNNGQTPFQVAVIAG 391
GAD + +G P +A ++G
Sbjct: 361 SGADTAKRGIHGMFPLHLAALSG 383
Score = 74.3 bits (181), Expect = 1e-12
Identities = 63/207 (30%), Positives = 91/207 (43%), Gaps = 7/207 (3%)
Query: 209 DSDSGET--PLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMTALHKAACARHCLALTAL 266
DSD+ T PL LAA G + + L +D R G T L AA H + L
Sbjct: 544 DSDNRATISPLHLAAY-HGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVL 602
Query: 267 LDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFN---RAQLGIADENGWQEIHQACQ 323
++ G S KD H A G C LL+ N + + I D NG + +
Sbjct: 603 INQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVL 662
Query: 324 RGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILLYRGADKDVKNNNGQTP 383
GH+ + LL GA A++ G TALH A+ E C LL GA ++++ G+TP
Sbjct: 663 NGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTP 722
Query: 384 FQVAVIAGNF-ELGELIRNHREQDVVP 409
++ G+ LG L+++ D P
Sbjct: 723 IHLSAACGHIGVLGALLQSAASMDANP 749
Score = 72.0 bits (175), Expect = 6e-12
Identities = 58/190 (30%), Positives = 83/190 (43%), Gaps = 3/190 (1%)
Query: 198 LLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMTALHKAACA 257
L+ G D N D G+TPL + A G +T+ GA ID ++G T LH AA
Sbjct: 292 LVGNGADVNMKSKD-GKTPLHMTA-LHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARY 349
Query: 258 RHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGIADENGWQE 317
H L + L+ G + G+ PL H A + G CC LL + + D+ G
Sbjct: 350 GHELLINTLITSGADTAKRGIHGMFPL-HLAALSGFSDCCRKLLSSGFDIDTPDDFGRTC 408
Query: 318 IHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILLYRGADKDVKN 377
+H A G+ + L LL GA+ ++ G + LH A C L+ GA + +
Sbjct: 409 LHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLD 468
Query: 378 NNGQTPFQVA 387
G TP A
Sbjct: 469 ERGCTPLHYA 478
Score = 71.6 bits (174), Expect = 8e-12
Identities = 59/200 (29%), Positives = 92/200 (46%), Gaps = 9/200 (4%)
Query: 191 TSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMTA 250
+ + V LL D N D + +TPL +AA + +V+ L ++++ R G TA
Sbjct: 86 SEEAVQVLLKHSADVNARDKN-WQTPLHIAAANK-AVKCAEALVPLLSNVNVSDRAGRTA 143
Query: 251 LHKAACARHCLALTALLDLGGSPNY---KDRRGLTPLFHTAMVGGDPRCCELLLFNRAQL 307
LH AA + H + LL G + N KDRR + H A G +LL+ + A++
Sbjct: 144 LHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAI----HWAAYMGHIEVVKLLVSHGAEV 199
Query: 308 GIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILL 367
D+ + +H A G +++LL G + NA GNT LH+ ++ L+
Sbjct: 200 TCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELI 259
Query: 368 YRGADKDVKNNNGQTPFQVA 387
GA + KN G TP A
Sbjct: 260 DCGAIVNQKNEKGFTPLHFA 279
Score = 68.9 bits (167), Expect = 5e-11
Identities = 60/226 (26%), Positives = 93/226 (41%), Gaps = 40/226 (17%)
Query: 212 SGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMTALHKAACARHCLALTALLDLGG 271
+G+TPL L+ G + + +L GA++D + + G TALH+ A H + ALL G
Sbjct: 652 NGQTPLMLSV-LNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGA 710
Query: 272 SPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQL----GIADENGWQEIHQACQRGHS 327
+D RG TP+ H + G LL + A + AD +G+ +H AC GH
Sbjct: 711 KCLLRDSRGRTPI-HLSAACGHIGVLGALLQSAASMDANPATADNHGYTALHWACYNGHE 769
Query: 328 QHLEHLL----FYGAEPGA------------------------------QNASGNTALHI 353
+E LL F E A ++ G T LH
Sbjct: 770 TCVELLLEQEVFQKTEGNAFSPLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHA 829
Query: 354 CALYNKETCARILLYRGADKDVKNNNGQTPFQVAVIAGNFELGELI 399
A + C ++LL A + ++ G+TP +A G E++
Sbjct: 830 AAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEML 875
Score = 62.0 bits (149), Expect = 6e-09
Identities = 52/211 (24%), Positives = 90/211 (42%), Gaps = 3/211 (1%)
Query: 214 ETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMTALHKAACARHCLALTALLDLGGSP 273
+ P + A G + +R L ++F+ + T LH AA + L+ G
Sbjct: 8 DQPSLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARV 67
Query: 274 NYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGIADENGWQEIHQACQRGHSQHLEHL 333
N KD + LTPL H A+ ++LL + A + D+N +H A + E L
Sbjct: 68 NAKDSKWLTPL-HRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEAL 126
Query: 334 LFYGAEPGAQNASGNTALHICALYNKETCARILLYRGADKDVKNNNGQTPFQVAVIAGNF 393
+ + + +G TALH A ++LL RGA+ + + + A G+
Sbjct: 127 VPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHI 186
Query: 394 ELGELIRNHREQDVVPFQES--PKYAARRRG 422
E+ +L+ +H + ++S P +AA G
Sbjct: 187 EVVKLLVSHGAEVTCKDKKSYTPLHAAASSG 217
Score = 54.7 bits (130), Expect = 1e-06
Identities = 49/164 (29%), Positives = 70/164 (42%), Gaps = 6/164 (3%)
Query: 224 EGSVEVIRTLCLGGAHIDFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTP 283
EG+ E++ LG + ++ G T LH AA H L LL N D G TP
Sbjct: 801 EGAAEMLIDT-LGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTP 859
Query: 284 LFHTAMVGGDPRCCELLLFNR-AQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEP-- 340
L A G E+L+ + A+L + D + +H AC +GH +L +
Sbjct: 860 LMMAAE-NGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHETSALLILEKITDRNL 918
Query: 341 -GAQNASGNTALHICALYNKETCARILLYRGADKDVKNNNGQTP 383
A NA+ T LH+ A + LL +GA + NG TP
Sbjct: 919 INATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTP 962
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 94.0 bits (232), Expect = 1e-18
Identities = 315/1347 (23%), Positives = 391/1347 (29%), Gaps = 271/1347 (20%)
Query: 832 TISASESPGPGGLASLGKHRPKGFFATESSFDPHHRAQPSYERPSFLPP--GPGLMLRQ- 888
T S S P G +G F E+ + Y P+ P GPG+ Q
Sbjct: 380 TADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDENYYDPYYDPTSSPSEIGPGMPANQD 439
Query: 889 ---KSIGAAEDDR-----PYLAPPAMKFSRSLSVPGSEDIPPPPTTSPP---------EP 931
+ IG ++ P + P M G +P PP T P
Sbjct: 440 TIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERG 499
Query: 932 PYSTPPVPSSSGRLTPSPRGG----PFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSL 987
P P +P + G P P G PF G GG + P S + +L
Sbjct: 500 PPGRPGLPGADG--LPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLAL 557
Query: 988 YH-SGPLP----PAHHHPPHHHHHHAPP----PQPHHHHAHPPHPPEME----------T 1028
+GP+ P PP P PQ PP P
Sbjct: 558 RGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGA 617
Query: 1029 GGSPDDPPPRL-----ALGPQPSLRGWRGG-GPSPTPGAPSPSHHGSAGGGGGSSQGPAL 1082
G P P+ L P +G RG GPS PG P G G G GP
Sbjct: 618 RGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDD--GERGDDG--EVGPR- 672
Query: 1083 RYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPP 1142
LP + P + G GP T ++G+P G + P P P P
Sbjct: 673 ---GLPGEPGPRGLLGP-KGPPGPPGP-PGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPG 727
Query: 1143 AVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAP 1202
A P + +I P K P G+ P + P G GG G
Sbjct: 728 AQGLPGPQGAIGPPGE--KGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGP------ 779
Query: 1203 AMSPVPPSPSPVPTPASPSGPATLDFTSQFGAALVGAARREGGWQNEARRRSTLFLSTDA 1262
P P P P P G G + + E G + + + D
Sbjct: 780 ---PGPQGPIGYPGPRGVKGAD--------GIRGLKGTKGEKGEDGFPGFKGDMGIKGDR 828
Query: 1263 GD--------EDGGDGGLGTGAA---PGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGYG 1311
G+ EDG +G G G PGP + G+ Y + G+
Sbjct: 829 GEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFP 888
Query: 1312 GYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKESSEGG 1371
G+ + GG G P +P G P P G E G
Sbjct: 889 GFPGANGEKGGRG--------TPGKPGPRGQRG----PTGPRG-----------ERGPRG 925
Query: 1372 GAPQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRE-----LGYRAGL 1426
+P P+ S + P P P+ P PP P ++ G R
Sbjct: 926 ITGKPGPKGNSGG-DGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGET 984
Query: 1427 GSQEKSLPASPPAARRSLLHRLPPTAPG--VGPLLLQLGTEPPAPHPGVSKPWRSAAPEE 1484
G Q K+ P PP + P P GP+ + PP P PG
Sbjct: 985 GFQGKTGPPGPPGV-------VGPQGPTGETGPMGERGHPGPPGP-PG------------ 1024
Query: 1485 PERLPLHVRFLENCQPRAPVTSG-RGPPSEDG-PGVPPPSPRRSVPPSPTSPRASEENGL 1542
E P G +G P G PG P R P P GL
Sbjct: 1025 -----------EQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGL 1073
Query: 1543 PLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPL 1602
PP P GE P + P P GPP P + AP
Sbjct: 1074 KGNEGPPGPPGPAGSPGE-------RGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKG 1126
Query: 1603 PP-------------VPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPG 1649
P +P PA PP D + G + GD G
Sbjct: 1127 PQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGE---------PGQKGSKGDKGEQG 1177
Query: 1650 PPAPAAPAPAAPQPGP---DPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGG 1706
PP P P QPGP D PG G + + + + P G
Sbjct: 1178 PPGPTGPQGPIGQPGPSGADGEPGP-RGQQGLFGQKGDEGPR-----------------G 1219
Query: 1707 SAGGGGGAGAGVASGP--ELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGR--AL 1762
G G G GP E +T G GPP PP PS G
Sbjct: 1220 FPGPPGPVGLQGLPGPPGEKGET----------GDVGQMGPPGPPGPRGPSGAPGADGPQ 1269
Query: 1763 GASGGL-RPGPSGGLRDPVTPTSPTVSVTGA--GTDGLLALRACSGPPTAGVAGGPVAVE 1819
G GG+ PG G +P P + G G G + SGP A GP
Sbjct: 1270 GPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPP 1329
Query: 1820 PEVPPVPLPTASSLPRKL-LPWEEGP----GPPPPP----------LPGPLAQPQASALA 1864
+ P P P P E GP GPP PGP +P S
Sbjct: 1330 GDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPP 1389
Query: 1865 TVKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQRQRL 1924
G G A P R G G G P +T + Q
Sbjct: 1390 -----------------GKRGPPGPAGPEGRQGEKGA--KGEAGLEGPPGKTGPIGPQGA 1430
Query: 1925 -SDDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGVSPTAAAAPGATSPSASSSSTSTRHL 1983
L P Q P P P P G P G + P L
Sbjct: 1431 PGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGL 1490
Query: 1984 QGVEFEMRPPLLRRAPSP--SLLPASEHKVSPAPRPSSLPILPSGPLYPGLFDIRGSPTG 2041
G E R P P S P E ++ PS PI P GP PGL P G
Sbjct: 1491 IGPPGEQGEKGDRGLPGPQGSSGPKGEQGITG---PSG-PIGPPGP--PGL----PGPPG 1540
Query: 2042 --GAGGSADPFAPVFVPPHPGISGGLG 2066
GA GS+ P P HPG G G
Sbjct: 1541 PKGAKGSSGPTGPKGEAGHPGPPGPPG 1567
Score = 94.0 bits (232), Expect = 1e-18
Identities = 262/1084 (24%), Positives = 329/1084 (30%), Gaps = 211/1084 (19%)
Query: 879 PPGPGLMLRQKSIGAAEDDRPYLAPPAMKFSRSLS----VPGSEDIPPPPTTSPPEPPYS 934
PPGP ++ ++ R K R +PG + P S P P
Sbjct: 599 PPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPG 658
Query: 935 TPPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLP 994
G + PRG P PG G L P GP P T + + + GP
Sbjct: 659 DDGERGDDGEV--GPRGLPGEPGPRGLLGPKGPPGPPGP-PGVTGMDGQPGPKGNVGP-- 713
Query: 995 PAHHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGG 1054
P P + G+ P P+ A+GP P +G G
Sbjct: 714 ----------------------QGEPGPPGQQGNPGAQGLPGPQGAIGP-PGEKGPLGKP 750
Query: 1055 PSP-TPGAPSPSHHGSAGG-----GGGSSQGPALRYFQLPPRAASAAMYVPARSG-RGRK 1107
P PGA P H G GG GP PR A + G +G K
Sbjct: 751 GLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEK 810
Query: 1108 G----PLVK-QTKVEGEPQKGGGLPPAP-------SPTSPASPQPPPA-VAAPSEKNSIP 1154
G P K ++G+ + G PP P P P P + P EK +
Sbjct: 811 GEDGFPGFKGDMGIKGDRGEIG--PPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLG 868
Query: 1155 IPTI-----------IIKAPSTSSSGRSSQGSSTEAEP-------PT------------- 1183
+P + I P + G T +P PT
Sbjct: 869 VPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITG 928
Query: 1184 QPEPTGGGGGGGSSPSPAPAMSPVPPSPSPVPTPASPSGPATLDFTSQFGAALVGAARRE 1243
+P P G GG G + P P P+ P P P GP D G R E
Sbjct: 929 KPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKD-----GLPGHPGQRGE 983
Query: 1244 GGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLES 1303
G+Q + + G G G +G PGP ++G+ P L +
Sbjct: 984 TGFQGKTGPPGPPGVVGPQGPT-GETGPMGERGHPGPP---GPPGEQGL----PGLAGKE 1035
Query: 1304 AGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALD----PASPLGLALAA 1359
G G G G F R L P+ L P P G A +
Sbjct: 1036 GTKG------DPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSP 1089
Query: 1360 RERALKESSEGGGAP-QPPPR-PPSPRYEAPPPTPHHHSPHAHHE----PVLRLWGASPP 1413
ER ++ G P +P P+ PP P E P A + PV A P
Sbjct: 1090 GERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPV 1149
Query: 1414 DPARR--------ELGYRAGLGSQEKSLPASPPAARRSLLHRLPPTAPGV-GP-----LL 1459
P E G + G + + P P + + P A G GP L
Sbjct: 1150 GPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLF 1209
Query: 1460 LQLGTEPPAPHPGVSKP-WRSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGPGV 1518
Q G E P PG P P P + GPP GP
Sbjct: 1210 GQKGDEGPRGFPGPPGPVGLQGLPGPPGE-----------KGETGDVGQMGPPGPPGPRG 1258
Query: 1519 PPPSPRRSVPPSPT----SPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFS 1574
P +P P P +P A E G P P P E G PP
Sbjct: 1259 PSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPG---EGG---------PPGPKG 1306
Query: 1575 NSFEKPESPLT-----PGPPHPLPDTPAPATP----LPPVPPPAVAAAPPTLDSTASSLT 1625
EK ES + PGP P D +P P P P P D
Sbjct: 1307 ERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKG 1366
Query: 1626 SYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSD 1685
G G P P G P P+ P PGP P G G + + +
Sbjct: 1367 D---------DGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQ-GEKGAKGEAGLE 1416
Query: 1686 HPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGP 1745
P G G G GA GP+ L + Q GS PGP
Sbjct: 1417 GP-----------------PGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGS--PGP 1457
Query: 1746 PYPPQLMTPSKLRGRALGASGGLRPGPSGGLRDP--VTPTSPTVSVTGAGTDGLLALRAC 1803
PP M P L G G SG P G P + P G GL +
Sbjct: 1458 DGPPGPMGPPGLPGLK-GDSG-----PKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGS 1511
Query: 1804 SGPP-TAGVAGGPVAVEPEVPP-VPLPTA------SSLPRKLLPWEEGPGPPPPP-LPGP 1854
SGP G+ G + P PP +P P SS P PGPP PP PG
Sbjct: 1512 SGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGE 1571
Query: 1855 LAQP 1858
+ QP
Sbjct: 1572 VIQP 1575
Score = 60.5 bits (145), Expect = 2e-08
Identities = 106/430 (24%), Positives = 136/430 (31%), Gaps = 88/430 (20%)
Query: 839 PGPGGL-ASLGKHRPKGFFATESSFDPHHRAQPSYERPSFLPPGPGLMLRQKSIGAAEDD 897
PGP G G +G F + P R P P L PG + G D
Sbjct: 1191 PGPSGADGEPGPRGQQGLFGQKGDEGP--RGFPGPPGPVGLQGLPGPPGEKGETG----D 1244
Query: 898 RPYLAPPAMKFSRSLS-VPGSEDIPPPP--------TTSPPEPPYSTPP-VPSSSGRLTP 947
+ PP R S PG++ PP EP + P +P G P
Sbjct: 1245 VGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGG--PP 1302
Query: 948 SPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHH 1007
P+G G GP A+ P GP D GS + P PP P
Sbjct: 1303 GPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGP------- 1355
Query: 1008 APPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHH 1067
A P P + + G +P P GP P RG P P P
Sbjct: 1356 AGQDGPPGDKGDDGEPGQTGSPGPTGEPGPS---GP-PGKRG------PPGPAGPEGRQG 1405
Query: 1068 GSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSG-RGRKGPLVKQTKVEGEPQKGGGL 1126
G +GP + + P+ A P G RG GP+ +Q GL
Sbjct: 1406 EKGAKGEAGLEGPPGKTGPIGPQGAPGK---PGPDGLRGIPGPVGEQ-----------GL 1451
Query: 1127 PPAPSPTSPASPQPPPAVAA-------PSEKNSIPIPTII-------------IKAPSTS 1166
P +P P P P PP + EK + +I + P S
Sbjct: 1452 PGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGS 1511
Query: 1167 SSGRSSQGSSTEAEPPTQPEPTG-------GGGGGGSSPS--------PAPAMSPVPPSP 1211
S + QG + + P P P G G G S P+ P P P PP
Sbjct: 1512 SGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGE 1571
Query: 1212 --SPVPTPAS 1219
P+P AS
Sbjct: 1572 VIQPLPIQAS 1581
Score = 53.5 bits (127), Expect = 2e-06
Identities = 92/400 (23%), Positives = 125/400 (31%), Gaps = 85/400 (21%)
Query: 1521 PSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKP 1580
P+P + P TS A +E + + D E + L + E P
Sbjct: 312 PTPTEAAPMPETSEGAGKEEDVGI-------GDYDYVPSEDYYTPSPYDDLTYGEGEENP 364
Query: 1581 ESPLTPGPPHPLPDTPA-PATPLPPVPPPAVAAAPPTLDSTASSL--------------T 1625
+ P PG +P + A + P PPP A + T ++ T
Sbjct: 365 DQPTDPGAGAEIPTSTADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDENYYDPYYDPT 424
Query: 1626 SYDSEVA--------TLTQGASAAPGDPHPPGPPA----------PAAPAPAAPQPGPDP 1667
S SE+ T+ +G G+ G PA P P A PGP
Sbjct: 425 SSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPG 484
Query: 1668 PPGTDSGIEEVDSRSSSDHP-------LETISSASTLSSLSAEGGGSAGGGGG-AGAGVA 1719
G + + R P L + GGG AG G A +
Sbjct: 485 TMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQES 544
Query: 1720 SGPELLDTYVAYLDGQA--FGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGPSGGLR 1777
+L L G A G + PGP PP G G G + P G++
Sbjct: 545 QAQAILQQARLALRGPAGPMGLTGRPGPVGPPG-------SGGLKGEPGDVGPQGPRGVQ 597
Query: 1778 DPVTPTSPTVSVTGAGTDGLLALRACSGPP-------TAGVAG----------------- 1813
P P AG+DG + +GP AG+ G
Sbjct: 598 GPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPP 657
Query: 1814 ---GPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPP 1850
G + EV P LP PR LL + PGPP PP
Sbjct: 658 GDDGERGDDGEVGPRGLPGEPG-PRGLLGPKGPPGPPGPP 696
Score = 39.7 bits (91), Expect = 0.032
Identities = 39/148 (26%), Positives = 49/148 (33%), Gaps = 9/148 (6%)
Query: 409 PFQESPKYAARRRGPPG-TGLTVP---PALLRANSDTSMALPDWMVFSAPGAASSGAPGP 464
P Q+ K +GPPG TG P P A+ + + G PGP
Sbjct: 1164 PGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGP 1223
Query: 465 TSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRG-----RPSS 519
Q P P K +G + P R PS + + P G
Sbjct: 1224 PGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGE 1283
Query: 520 SGTPREGPAGGTGGSGGPGGSLGSRGRR 547
G P E G G GGP G G RG +
Sbjct: 1284 KGEPGEAGEPGLPGEGGPPGPKGERGEK 1311
Score = 38.9 bits (89), Expect = 0.055
Identities = 40/153 (26%), Positives = 53/153 (34%), Gaps = 47/153 (30%)
Query: 408 VPFQESPKYAARRRGPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAAS-SGAPGPTS 466
+P + P+ +GPPG PP PG G PGP
Sbjct: 674 LPGEPGPRGLLGPKGPPG-----PPG-------------------PPGVTGMDGQPGPKG 709
Query: 467 GSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTP--- 523
Q +P P + + G + P+GA +G P G+P G P
Sbjct: 710 NVGPQGEPGPPGQQGNPGA-QGLPGPQGAIGPPGEKG---------PLGKPGLPGMPGAD 759
Query: 524 -------REGPAGGTGGSG--GPGGSLGSRGRR 547
+EGP G GG G GP G +G G R
Sbjct: 760 GPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPR 792
Score = 35.8 bits (81), Expect = 0.47
Identities = 42/148 (28%), Positives = 47/148 (31%), Gaps = 24/148 (16%)
Query: 422 GPPGT----GLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQSQPSAP 477
GPPG GL PP D P + + GA GP G P A
Sbjct: 1222 GPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAV 1281
Query: 478 TTKLSSGTLRSASSP-----------RGARARS-PSRGRHPEDAKRQP-----RGRPSSS 520
K G P RG + S PS P K P +G P
Sbjct: 1282 GEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPV 1341
Query: 521 GTPRE-GPAG--GTGGSGGPGGSLGSRG 545
G P + GP G G G GP G G G
Sbjct: 1342 GFPGDPGPPGEPGPAGQDGPPGDKGDDG 1369
Score = 35.0 bits (79), Expect = 0.80
Identities = 31/113 (27%), Positives = 38/113 (33%), Gaps = 11/113 (9%)
Query: 454 PGAASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQP 513
PG P +G G+ P L + G + G +D
Sbjct: 996 PGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGL 1055
Query: 514 RGRPSSSGTPREGPAGGTG-----GSGGPGGSLGSRGRRRKLYSA----VPGR 557
RG P G P GP G G G GP G GS G R +A +PGR
Sbjct: 1056 RGFPGDRGLP--GPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGR 1106
Score = 34.3 bits (77), Expect = 1.4
Identities = 36/150 (24%), Positives = 47/150 (31%), Gaps = 24/150 (16%)
Query: 422 GPPGTGLTVP------------PALLRANSDTSMALPDWMVFSAPGAAS----SGAPGPT 465
GPPGT L +P ++ A + A+ + G A +G PGP
Sbjct: 514 GPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPV 573
Query: 466 S--------GSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRP 517
G G P P RG +RG + + RG
Sbjct: 574 GPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFD 633
Query: 518 SSSGTPREGPAGGTGGSGGPGGSLGSRGRR 547
+G P E G G GP G G G R
Sbjct: 634 GLAGLPGEKGHRGDPGPSGPPGPPGDDGER 663
Score = 34.3 bits (77), Expect = 1.4
Identities = 28/86 (32%), Positives = 33/86 (38%), Gaps = 25/86 (29%)
Query: 460 GAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSS 519
G PG G+ P P PRG R + RG +R PRG
Sbjct: 889 GFPGANGEKGGRGTPGKP-------------GPRGQRGPTGPRG------ERGPRGI--- 926
Query: 520 SGTPREGPAGGTGGSGGPGGSLGSRG 545
T + GP G +GG G P G G RG
Sbjct: 927 --TGKPGPKGNSGGDG-PAGPPGERG 949
Score = 34.3 bits (77), Expect = 1.4
Identities = 28/93 (30%), Positives = 35/93 (37%), Gaps = 17/93 (18%)
Query: 455 GAASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPR 514
G + G PGP +GQ P+ P R PRG + +G D P
Sbjct: 899 GRGTPGKPGP----RGQRGPTGP---------RGERGPRGITGKPGPKGNSGGDGPAGPP 945
Query: 515 GRPSSSGTPREGPAGGTGGSG--GPGGSLGSRG 545
G +G +GP G G G GP G G G
Sbjct: 946 GERGPNGP--QGPTGFPGPKGPPGPPGKDGLPG 976
Score = 33.9 bits (76), Expect = 1.8
Identities = 28/95 (29%), Positives = 35/95 (36%), Gaps = 26/95 (27%)
Query: 459 SGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPS 518
+G+PGPT G+ PS P K R P G R +G E P G+
Sbjct: 1374 TGSPGPT----GEPGPSGPPGK------RGPPGPAGPEGRQGEKGAKGEAGLEGPPGKT- 1422
Query: 519 SSGTPREGPAGGTGGSGGPG--------GSLGSRG 545
GP G G G PG G +G +G
Sbjct: 1423 -------GPIGPQGAPGKPGPDGLRGIPGPVGEQG 1450
Score = 33.5 bits (75), Expect = 2.3
Identities = 29/100 (29%), Positives = 40/100 (40%), Gaps = 14/100 (14%)
Query: 460 GAPGPT--SGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDA------KR 511
G PG +G QG++ P P + + P G R G E K
Sbjct: 976 GHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKE 1035
Query: 512 QPRGRPSSSGTP-REGPAG-----GTGGSGGPGGSLGSRG 545
+G P +G P ++GP G G G GP G+LG +G
Sbjct: 1036 GTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKG 1075
Score = 33.1 bits (74), Expect = 3.0
Identities = 28/99 (28%), Positives = 35/99 (35%), Gaps = 9/99 (9%)
Query: 459 SGAPGPTS--GSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGR 516
SG PGP G +G P R P+G G D + P+G
Sbjct: 651 SGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGN 710
Query: 517 PSSSGTPREGPAGGTGGSG-----GPGGSLGSRGRRRKL 550
G P GP G G G GP G++G G + L
Sbjct: 711 VGPQGEP--GPPGQQGNPGAQGLPGPQGAIGPPGEKGPL 747
Score = 32.7 bits (73), Expect = 4.0
Identities = 25/89 (28%), Positives = 28/89 (31%), Gaps = 2/89 (2%)
Query: 460 GAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSR--GRHPEDAKRQPRGRP 517
G PGP Q P K G SP PS G+ P GR
Sbjct: 1345 GDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQ 1404
Query: 518 SSSGTPREGPAGGTGGSGGPGGSLGSRGR 546
G E G G GP G G+ G+
Sbjct: 1405 GEKGAKGEAGLEGPPGKTGPIGPQGAPGK 1433
Score = 32.7 bits (73), Expect = 4.0
Identities = 37/128 (28%), Positives = 43/128 (33%), Gaps = 25/128 (19%)
Query: 421 RGPPGT-GLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQSQPSAPTT 479
+G PG GL PP D + PG S P G QG + PS P
Sbjct: 1482 KGHPGLIGLIGPPGEQGEKGDRGL----------PGPQGSSGP---KGEQGITGPSGPIG 1528
Query: 480 KLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPREGPAGGTGGSGGPGG 539
L P+GA+ S G P+G G P GP G G P
Sbjct: 1529 PPGPPGLPGPPGPKGAKGSSGPTG---------PKGEAGHPGPP--GPPGPPGEVIQPLP 1577
Query: 540 SLGSRGRR 547
SR RR
Sbjct: 1578 IQASRTRR 1585
Score = 32.3 bits (72), Expect = 5.2
Identities = 34/115 (29%), Positives = 41/115 (35%), Gaps = 17/115 (14%)
Query: 454 PGAASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQP 513
PG P G QG P P ++ A RG + ++G ED
Sbjct: 762 PGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKG---TKGEKGEDGFPGF 818
Query: 514 RGRPSSSGTPRE----GPAGGTG-----GSGGPGGS---LGSRGRRRKLYSAVPG 556
+G G E GP G G G GGP G LG G + KL VPG
Sbjct: 819 KGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKL--GVPG 871
Score = 32.3 bits (72), Expect = 5.2
Identities = 39/154 (25%), Positives = 48/154 (31%), Gaps = 29/154 (18%)
Query: 422 GPPGT-------GLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQSQP 474
GPPG GL P L + P S +GA GP G G+ P
Sbjct: 1051 GPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPI-GIPGRPGP 1109
Query: 475 SAPTTKLSSGTLRSASSPRGARARSPSR------------GRHPEDAKRQPRGRPSSSGT 522
P P+G R + G ED + G P G+
Sbjct: 1110 QGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGS 1169
Query: 523 P----REGPAGGTG-----GSGGPGGSLGSRGRR 547
+GP G TG G GP G+ G G R
Sbjct: 1170 KGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPR 1203
Score = 32.3 bits (72), Expect = 5.2
Identities = 27/96 (28%), Positives = 33/96 (34%), Gaps = 12/96 (12%)
Query: 460 GAPGPTSGSQGQSQPSAPTTKLSSGT--------LRSASSPRGARARSPSRGRHPEDAKR 511
G+PGP P P K SG L P G + RG
Sbjct: 1453 GSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSS 1512
Query: 512 QPRGRPSSSGTPREGPAGGTGGSG--GPGGSLGSRG 545
P+G +G GP G G G GP G G++G
Sbjct: 1513 GPKGEQGITGP--SGPIGPPGPPGLPGPPGPKGAKG 1546
Score = 32.0 bits (71), Expect = 6.8
Identities = 41/149 (27%), Positives = 53/149 (35%), Gaps = 32/149 (21%)
Query: 421 RGPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTS--GSQGQSQPSA-- 476
+GPPG G+ P A+ P PG G PGP G +G+S PS
Sbjct: 1269 QGPPG-GIGNPGAVGEKGEPGEAGEP-----GLPG--EGGPPGPKGERGEKGESGPSGAA 1320
Query: 477 --PTTKLSSGTLRSASSPR--------------GARARSPSRGRHPEDAKRQPRGRPSSS 520
P K G SP G + G +D + G P +
Sbjct: 1321 GPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPT 1380
Query: 521 GTPREGPAGGTGGSG--GPGGSLGSRGRR 547
G P GP+G G G GP G G +G +
Sbjct: 1381 GEP--GPSGPPGKRGPPGPAGPEGRQGEK 1407
Score = 31.6 bits (70), Expect = 8.8
Identities = 26/94 (27%), Positives = 30/94 (31%), Gaps = 4/94 (4%)
Query: 454 PGAASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQP 513
PG P G G P + R P+G+ +G P
Sbjct: 1470 PGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGP 1529
Query: 514 RGRPSSSGTPREGPAGGTGGSG--GPGGSLGSRG 545
G P G P GP G G SG GP G G G
Sbjct: 1530 PGPPGLPGPP--GPKGAKGSSGPTGPKGEAGHPG 1561
>gi|188595682 ankyrin 2 isoform 3 [Homo sapiens]
Length = 1863
Score = 93.6 bits (231), Expect = 2e-18
Identities = 95/364 (26%), Positives = 150/364 (41%), Gaps = 53/364 (14%)
Query: 165 NLDEKQLAKLHTKTGLKKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTE 224
++ K + T++G G + LL++G ++ + +G TPL +A++
Sbjct: 198 DVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDF-TARNGITPLHVASK-R 255
Query: 225 GSVEVIRTLCLGGAHIDFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPL 284
G+ +++ L G ID + RDG+T LH AA + H + LL+ G + + GL+PL
Sbjct: 256 GNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPL 315
Query: 285 --------------------------------FHTAMVGGDPRCCELLLFNRAQLGIADE 312
H A G R +LLL RA
Sbjct: 316 HMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARAL 375
Query: 313 NGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILLYRGAD 372
NG+ +H AC++ + +E L+ YGA A SG T +H+ A +LL GA
Sbjct: 376 NGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGAS 435
Query: 373 KDVKNNNGQTPFQVAVIAGNFELGE-LIRNHREQDVVPFQE-SPKYAARRRGPPGTGLTV 430
DV N G+T +A AG E+ L+RN D +E +P + A R G +
Sbjct: 436 PDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGK----TEI 491
Query: 431 PPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSAS 490
LL+ MA PD AA++ P S + Q + L +G S +
Sbjct: 492 VQLLLQ-----HMAHPD--------AATTNGYTPLHISAREGQVDVASVLLEAGAAHSLA 538
Query: 491 SPRG 494
+ +G
Sbjct: 539 TKKG 542
Score = 87.4 bits (215), Expect = 1e-16
Identities = 74/249 (29%), Positives = 113/249 (45%), Gaps = 5/249 (2%)
Query: 176 TKTGLKKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCL 235
T++GL +G + V LL G P+ + GET L +AA+ G VEV+R L
Sbjct: 407 TESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNI-RGETALHMAARA-GQVEVVRCLLR 464
Query: 236 GGAHIDFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPR 295
GA +D RAR+ T LH A+ + LL P+ G TPL H + G
Sbjct: 465 NGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPL-HISAREGQVD 523
Query: 296 CCELLLFNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICA 355
+LL A +A + G+ +H A + G + LL A + +G T LH+ A
Sbjct: 524 VASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAA 583
Query: 356 LYNKETCARILLYRGADKDVKNNNGQTPFQVAVIAGNFELGELIRNH-REQDVVPFQ-ES 413
Y+ + A +LL +GA NG TP +A ++ + N+ E ++V Q +
Sbjct: 584 HYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVT 643
Query: 414 PKYAARRRG 422
P + A + G
Sbjct: 644 PLHLASQEG 652
Score = 87.4 bits (215), Expect = 1e-16
Identities = 69/206 (33%), Positives = 97/206 (47%), Gaps = 3/206 (1%)
Query: 190 GTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMT 249
G D + LL+ G + + G TPL +AA+ GS++V + L A D ++G+T
Sbjct: 520 GQVDVASVLLEAGAAHSLA-TKKGFTPLHVAAKY-GSLDVAKLLLQRRAAADSAGKNGLT 577
Query: 250 ALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGI 309
LH AA + LL+ G SP+ + G TPL H A + LL A+ I
Sbjct: 578 PLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPL-HIAAKKNQMQIASTLLNYGAETNI 636
Query: 310 ADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILLYR 369
+ G +H A Q GH+ + LL GA SG T+LH+ A +K A IL
Sbjct: 637 VTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKH 696
Query: 370 GADKDVKNNNGQTPFQVAVIAGNFEL 395
GAD+D G TP VA GN ++
Sbjct: 697 GADQDAHTKLGYTPLIVACHYGNVKM 722
Score = 83.6 bits (205), Expect = 2e-15
Identities = 65/206 (31%), Positives = 96/206 (46%), Gaps = 3/206 (1%)
Query: 198 LLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMTALHKAACA 257
LLDK +PN + +G TPL +A + + ++V+ L GA I G+T +H AA
Sbjct: 363 LLDKRANPNAR-ALNGFTPLHIACK-KNRIKVMELLVKYGASIQAITESGLTPIHVAAFM 420
Query: 258 RHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGIADENGWQE 317
H + LL G SP+ + RG T L H A G LL N A +
Sbjct: 421 GHLNIVLLLLQNGASPDVTNIRGETAL-HMAARAGQVEVVRCLLRNGALVDARAREEQTP 479
Query: 318 IHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILLYRGADKDVKN 377
+H A + G ++ ++ LL + A P A +G T LHI A + A +LL GA +
Sbjct: 480 LHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLAT 539
Query: 378 NNGQTPFQVAVIAGNFELGELIRNHR 403
G TP VA G+ ++ +L+ R
Sbjct: 540 KKGFTPLHVAAKYGSLDVAKLLLQRR 565
Score = 79.7 bits (195), Expect = 3e-14
Identities = 79/279 (28%), Positives = 115/279 (41%), Gaps = 42/279 (15%)
Query: 183 FLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDF 242
FL + G DKV L G+D N + + G L LAA+ EG V +++ L G+ +D
Sbjct: 14 FLRAARAGNLDKVVEYLKGGIDINTCNQN-GLNALHLAAK-EGHVGLVQELLGRGSSVDS 71
Query: 243 RARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLF 302
+ G TALH A+ A + L+ G + N + + G TPL+ A + LL
Sbjct: 72 ATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQ-ENHIDVVKYLLE 130
Query: 303 NRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQ------------------- 343
N A A E+G+ + A Q+GH+Q + LL + +
Sbjct: 131 NGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALL 190
Query: 344 ------------------NASGNTALHICALYNKETCARILLYRGADKDVKNNNGQTPFQ 385
SG T LHI A Y A +LL RGA D NG TP
Sbjct: 191 LQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLH 250
Query: 386 VAVIAGNFELGELIRNHREQDVVPFQE--SPKYAARRRG 422
VA GN + +L+ + Q ++ +P + A R G
Sbjct: 251 VASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSG 289
Score = 79.0 bits (193), Expect = 5e-14
Identities = 55/156 (35%), Positives = 80/156 (51%), Gaps = 3/156 (1%)
Query: 198 LLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMTALHKAACA 257
LL+ G + N + G TPL LA+Q EG +++ L GA+I + G+T+LH AA
Sbjct: 627 LLNYGAETNIV-TKQGVTPLHLASQ-EGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQE 684
Query: 258 RHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGIADENGWQE 317
L G + + G TPL A G+ + LL A + +NG+
Sbjct: 685 DKVNVADILTKHGADQDAHTKLGYTPLI-VACHYGNVKMVNFLLKQGANVNAKTKNGYTP 743
Query: 318 IHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHI 353
+HQA Q+GH+ + LL +GA+P A A+GNTAL I
Sbjct: 744 LHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAI 779
Score = 76.3 bits (186), Expect = 3e-13
Identities = 66/229 (28%), Positives = 98/229 (42%), Gaps = 3/229 (1%)
Query: 174 LHTKTGLKKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTL 233
L TK G + G+ D VA+LL + +G TPL +AA + +V L
Sbjct: 537 LATKKGFTPLHVAAKYGSLD-VAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQ-KVALLL 594
Query: 234 CLGGAHIDFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGD 293
GA A++G T LH AA + LL+ G N ++G+TPL H A G
Sbjct: 595 LEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPL-HLASQEGH 653
Query: 294 PRCCELLLFNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHI 353
LLL A + ++ ++G +H A Q + L +GA+ A G T L +
Sbjct: 654 TDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIV 713
Query: 354 CALYNKETCARILLYRGADKDVKNNNGQTPFQVAVIAGNFELGELIRNH 402
Y LL +GA+ + K NG TP A G+ + ++ H
Sbjct: 714 ACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQH 762
Score = 74.7 bits (182), Expect = 9e-13
Identities = 57/203 (28%), Positives = 93/203 (45%), Gaps = 3/203 (1%)
Query: 198 LLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMTALHKAACA 257
LL+KG P + + +G TPL +AA+ + +++ TL GA + + G+T LH A+
Sbjct: 594 LLEKGASP-HATAKNGYTPLHIAAK-KNQMQIASTLLNYGAETNIVTKQGVTPLHLASQE 651
Query: 258 RHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGIADENGWQE 317
H +T LLD G + + + GLT L H A ++L + A + G+
Sbjct: 652 GHTDMVTLLLDKGANIHMSTKSGLTSL-HLAAQEDKVNVADILTKHGADQDAHTKLGYTP 710
Query: 318 IHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILLYRGADKDVKN 377
+ AC G+ + + LL GA A+ +G T LH A +LL GA +
Sbjct: 711 LIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATT 770
Query: 378 NNGQTPFQVAVIAGNFELGELIR 400
NG T +A G + + ++
Sbjct: 771 ANGNTALAIAKRLGYISVVDTLK 793
Score = 65.1 bits (157), Expect = 7e-10
Identities = 67/251 (26%), Positives = 99/251 (39%), Gaps = 40/251 (15%)
Query: 190 GTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMT 249
G ++ V L+ +G + N S +G TPL +AAQ E ++V++ L GA+ DG T
Sbjct: 87 GQAEVVKVLVKEGANINAQ-SQNGFTPLYMAAQ-ENHIDVVKYLLENGANQSTATEDGFT 144
Query: 250 ALHKAACARHCLALTALL--DLGGSP---------------------------------- 273
L A H A+ LL D G
Sbjct: 145 PLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMM 204
Query: 274 -NYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGIADENGWQEIHQACQRGHSQHLEH 332
N G TPL H A G+ LLL A + NG +H A +RG++ ++
Sbjct: 205 VNRTTESGFTPL-HIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKL 263
Query: 333 LLFYGAEPGAQNASGNTALHICALYNKETCARILLYRGADKDVKNNNGQTPFQVAVIAGN 392
LL G + A+ G T LH A + +LL RGA + NG +P +A +
Sbjct: 264 LLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDH 323
Query: 393 FELGELIRNHR 403
E + + H+
Sbjct: 324 VECVKHLLQHK 334
>gi|52426737 ankyrin 2 isoform 2 [Homo sapiens]
Length = 1872
Score = 93.6 bits (231), Expect = 2e-18
Identities = 95/364 (26%), Positives = 150/364 (41%), Gaps = 53/364 (14%)
Query: 165 NLDEKQLAKLHTKTGLKKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTE 224
++ K + T++G G + LL++G ++ + +G TPL +A++
Sbjct: 219 DVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDF-TARNGITPLHVASK-R 276
Query: 225 GSVEVIRTLCLGGAHIDFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPL 284
G+ +++ L G ID + RDG+T LH AA + H + LL+ G + + GL+PL
Sbjct: 277 GNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPL 336
Query: 285 --------------------------------FHTAMVGGDPRCCELLLFNRAQLGIADE 312
H A G R +LLL RA
Sbjct: 337 HMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARAL 396
Query: 313 NGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILLYRGAD 372
NG+ +H AC++ + +E L+ YGA A SG T +H+ A +LL GA
Sbjct: 397 NGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGAS 456
Query: 373 KDVKNNNGQTPFQVAVIAGNFELGE-LIRNHREQDVVPFQE-SPKYAARRRGPPGTGLTV 430
DV N G+T +A AG E+ L+RN D +E +P + A R G +
Sbjct: 457 PDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGK----TEI 512
Query: 431 PPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSAS 490
LL+ MA PD AA++ P S + Q + L +G S +
Sbjct: 513 VQLLLQ-----HMAHPD--------AATTNGYTPLHISAREGQVDVASVLLEAGAAHSLA 559
Query: 491 SPRG 494
+ +G
Sbjct: 560 TKKG 563
Score = 87.4 bits (215), Expect = 1e-16
Identities = 74/249 (29%), Positives = 113/249 (45%), Gaps = 5/249 (2%)
Query: 176 TKTGLKKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCL 235
T++GL +G + V LL G P+ + GET L +AA+ G VEV+R L
Sbjct: 428 TESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNI-RGETALHMAARA-GQVEVVRCLLR 485
Query: 236 GGAHIDFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPR 295
GA +D RAR+ T LH A+ + LL P+ G TPL H + G
Sbjct: 486 NGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPL-HISAREGQVD 544
Query: 296 CCELLLFNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICA 355
+LL A +A + G+ +H A + G + LL A + +G T LH+ A
Sbjct: 545 VASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAA 604
Query: 356 LYNKETCARILLYRGADKDVKNNNGQTPFQVAVIAGNFELGELIRNH-REQDVVPFQ-ES 413
Y+ + A +LL +GA NG TP +A ++ + N+ E ++V Q +
Sbjct: 605 HYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVT 664
Query: 414 PKYAARRRG 422
P + A + G
Sbjct: 665 PLHLASQEG 673
Score = 87.4 bits (215), Expect = 1e-16
Identities = 69/206 (33%), Positives = 97/206 (47%), Gaps = 3/206 (1%)
Query: 190 GTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMT 249
G D + LL+ G + + G TPL +AA+ GS++V + L A D ++G+T
Sbjct: 541 GQVDVASVLLEAGAAHSLA-TKKGFTPLHVAAKY-GSLDVAKLLLQRRAAADSAGKNGLT 598
Query: 250 ALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGI 309
LH AA + LL+ G SP+ + G TPL H A + LL A+ I
Sbjct: 599 PLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPL-HIAAKKNQMQIASTLLNYGAETNI 657
Query: 310 ADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILLYR 369
+ G +H A Q GH+ + LL GA SG T+LH+ A +K A IL
Sbjct: 658 VTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKH 717
Query: 370 GADKDVKNNNGQTPFQVAVIAGNFEL 395
GAD+D G TP VA GN ++
Sbjct: 718 GADQDAHTKLGYTPLIVACHYGNVKM 743
Score = 83.6 bits (205), Expect = 2e-15
Identities = 65/206 (31%), Positives = 96/206 (46%), Gaps = 3/206 (1%)
Query: 198 LLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMTALHKAACA 257
LLDK +PN + +G TPL +A + + ++V+ L GA I G+T +H AA
Sbjct: 384 LLDKRANPNAR-ALNGFTPLHIACK-KNRIKVMELLVKYGASIQAITESGLTPIHVAAFM 441
Query: 258 RHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGIADENGWQE 317
H + LL G SP+ + RG T L H A G LL N A +
Sbjct: 442 GHLNIVLLLLQNGASPDVTNIRGETAL-HMAARAGQVEVVRCLLRNGALVDARAREEQTP 500
Query: 318 IHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILLYRGADKDVKN 377
+H A + G ++ ++ LL + A P A +G T LHI A + A +LL GA +
Sbjct: 501 LHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLAT 560
Query: 378 NNGQTPFQVAVIAGNFELGELIRNHR 403
G TP VA G+ ++ +L+ R
Sbjct: 561 KKGFTPLHVAAKYGSLDVAKLLLQRR 586
Score = 79.7 bits (195), Expect = 3e-14
Identities = 79/279 (28%), Positives = 115/279 (41%), Gaps = 42/279 (15%)
Query: 183 FLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDF 242
FL + G DKV L G+D N + + G L LAA+ EG V +++ L G+ +D
Sbjct: 35 FLRAARAGNLDKVVEYLKGGIDINTCNQN-GLNALHLAAK-EGHVGLVQELLGRGSSVDS 92
Query: 243 RARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLF 302
+ G TALH A+ A + L+ G + N + + G TPL+ A + LL
Sbjct: 93 ATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQ-ENHIDVVKYLLE 151
Query: 303 NRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQ------------------- 343
N A A E+G+ + A Q+GH+Q + LL + +
Sbjct: 152 NGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALL 211
Query: 344 ------------------NASGNTALHICALYNKETCARILLYRGADKDVKNNNGQTPFQ 385
SG T LHI A Y A +LL RGA D NG TP
Sbjct: 212 LQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLH 271
Query: 386 VAVIAGNFELGELIRNHREQDVVPFQE--SPKYAARRRG 422
VA GN + +L+ + Q ++ +P + A R G
Sbjct: 272 VASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSG 310
Score = 79.0 bits (193), Expect = 5e-14
Identities = 55/156 (35%), Positives = 80/156 (51%), Gaps = 3/156 (1%)
Query: 198 LLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMTALHKAACA 257
LL+ G + N + G TPL LA+Q EG +++ L GA+I + G+T+LH AA
Sbjct: 648 LLNYGAETNIV-TKQGVTPLHLASQ-EGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQE 705
Query: 258 RHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGIADENGWQE 317
L G + + G TPL A G+ + LL A + +NG+
Sbjct: 706 DKVNVADILTKHGADQDAHTKLGYTPLI-VACHYGNVKMVNFLLKQGANVNAKTKNGYTP 764
Query: 318 IHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHI 353
+HQA Q+GH+ + LL +GA+P A A+GNTAL I
Sbjct: 765 LHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAI 800
Score = 76.3 bits (186), Expect = 3e-13
Identities = 66/229 (28%), Positives = 98/229 (42%), Gaps = 3/229 (1%)
Query: 174 LHTKTGLKKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTL 233
L TK G + G+ D VA+LL + +G TPL +AA + +V L
Sbjct: 558 LATKKGFTPLHVAAKYGSLD-VAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQ-KVALLL 615
Query: 234 CLGGAHIDFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGD 293
GA A++G T LH AA + LL+ G N ++G+TPL H A G
Sbjct: 616 LEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPL-HLASQEGH 674
Query: 294 PRCCELLLFNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHI 353
LLL A + ++ ++G +H A Q + L +GA+ A G T L +
Sbjct: 675 TDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIV 734
Query: 354 CALYNKETCARILLYRGADKDVKNNNGQTPFQVAVIAGNFELGELIRNH 402
Y LL +GA+ + K NG TP A G+ + ++ H
Sbjct: 735 ACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQH 783
Score = 74.7 bits (182), Expect = 9e-13
Identities = 57/203 (28%), Positives = 93/203 (45%), Gaps = 3/203 (1%)
Query: 198 LLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMTALHKAACA 257
LL+KG P + + +G TPL +AA+ + +++ TL GA + + G+T LH A+
Sbjct: 615 LLEKGASP-HATAKNGYTPLHIAAK-KNQMQIASTLLNYGAETNIVTKQGVTPLHLASQE 672
Query: 258 RHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGIADENGWQE 317
H +T LLD G + + + GLT L H A ++L + A + G+
Sbjct: 673 GHTDMVTLLLDKGANIHMSTKSGLTSL-HLAAQEDKVNVADILTKHGADQDAHTKLGYTP 731
Query: 318 IHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILLYRGADKDVKN 377
+ AC G+ + + LL GA A+ +G T LH A +LL GA +
Sbjct: 732 LIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATT 791
Query: 378 NNGQTPFQVAVIAGNFELGELIR 400
NG T +A G + + ++
Sbjct: 792 ANGNTALAIAKRLGYISVVDTLK 814
Score = 65.1 bits (157), Expect = 7e-10
Identities = 67/251 (26%), Positives = 99/251 (39%), Gaps = 40/251 (15%)
Query: 190 GTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMT 249
G ++ V L+ +G + N S +G TPL +AAQ E ++V++ L GA+ DG T
Sbjct: 108 GQAEVVKVLVKEGANINAQ-SQNGFTPLYMAAQ-ENHIDVVKYLLENGANQSTATEDGFT 165
Query: 250 ALHKAACARHCLALTALL--DLGGSP---------------------------------- 273
L A H A+ LL D G
Sbjct: 166 PLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMM 225
Query: 274 -NYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGIADENGWQEIHQACQRGHSQHLEH 332
N G TPL H A G+ LLL A + NG +H A +RG++ ++
Sbjct: 226 VNRTTESGFTPL-HIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKL 284
Query: 333 LLFYGAEPGAQNASGNTALHICALYNKETCARILLYRGADKDVKNNNGQTPFQVAVIAGN 392
LL G + A+ G T LH A + +LL RGA + NG +P +A +
Sbjct: 285 LLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDH 344
Query: 393 FELGELIRNHR 403
E + + H+
Sbjct: 345 VECVKHLLQHK 355
>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
Length = 3957
Score = 93.6 bits (231), Expect = 2e-18
Identities = 95/364 (26%), Positives = 150/364 (41%), Gaps = 53/364 (14%)
Query: 165 NLDEKQLAKLHTKTGLKKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTE 224
++ K + T++G G + LL++G ++ + +G TPL +A++
Sbjct: 219 DVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDF-TARNGITPLHVASK-R 276
Query: 225 GSVEVIRTLCLGGAHIDFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPL 284
G+ +++ L G ID + RDG+T LH AA + H + LL+ G + + GL+PL
Sbjct: 277 GNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPL 336
Query: 285 --------------------------------FHTAMVGGDPRCCELLLFNRAQLGIADE 312
H A G R +LLL RA
Sbjct: 337 HMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARAL 396
Query: 313 NGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILLYRGAD 372
NG+ +H AC++ + +E L+ YGA A SG T +H+ A +LL GA
Sbjct: 397 NGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGAS 456
Query: 373 KDVKNNNGQTPFQVAVIAGNFELGE-LIRNHREQDVVPFQE-SPKYAARRRGPPGTGLTV 430
DV N G+T +A AG E+ L+RN D +E +P + A R G +
Sbjct: 457 PDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGK----TEI 512
Query: 431 PPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSAS 490
LL+ MA PD AA++ P S + Q + L +G S +
Sbjct: 513 VQLLLQ-----HMAHPD--------AATTNGYTPLHISAREGQVDVASVLLEAGAAHSLA 559
Query: 491 SPRG 494
+ +G
Sbjct: 560 TKKG 563
Score = 87.4 bits (215), Expect = 1e-16
Identities = 74/249 (29%), Positives = 113/249 (45%), Gaps = 5/249 (2%)
Query: 176 TKTGLKKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCL 235
T++GL +G + V LL G P+ + GET L +AA+ G VEV+R L
Sbjct: 428 TESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNI-RGETALHMAARA-GQVEVVRCLLR 485
Query: 236 GGAHIDFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPR 295
GA +D RAR+ T LH A+ + LL P+ G TPL H + G
Sbjct: 486 NGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPL-HISAREGQVD 544
Query: 296 CCELLLFNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICA 355
+LL A +A + G+ +H A + G + LL A + +G T LH+ A
Sbjct: 545 VASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAA 604
Query: 356 LYNKETCARILLYRGADKDVKNNNGQTPFQVAVIAGNFELGELIRNH-REQDVVPFQ-ES 413
Y+ + A +LL +GA NG TP +A ++ + N+ E ++V Q +
Sbjct: 605 HYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVT 664
Query: 414 PKYAARRRG 422
P + A + G
Sbjct: 665 PLHLASQEG 673
Score = 87.4 bits (215), Expect = 1e-16
Identities = 69/206 (33%), Positives = 97/206 (47%), Gaps = 3/206 (1%)
Query: 190 GTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMT 249
G D + LL+ G + + G TPL +AA+ GS++V + L A D ++G+T
Sbjct: 541 GQVDVASVLLEAGAAHSLA-TKKGFTPLHVAAKY-GSLDVAKLLLQRRAAADSAGKNGLT 598
Query: 250 ALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGI 309
LH AA + LL+ G SP+ + G TPL H A + LL A+ I
Sbjct: 599 PLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPL-HIAAKKNQMQIASTLLNYGAETNI 657
Query: 310 ADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILLYR 369
+ G +H A Q GH+ + LL GA SG T+LH+ A +K A IL
Sbjct: 658 VTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKH 717
Query: 370 GADKDVKNNNGQTPFQVAVIAGNFEL 395
GAD+D G TP VA GN ++
Sbjct: 718 GADQDAHTKLGYTPLIVACHYGNVKM 743
Score = 83.6 bits (205), Expect = 2e-15
Identities = 65/206 (31%), Positives = 96/206 (46%), Gaps = 3/206 (1%)
Query: 198 LLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMTALHKAACA 257
LLDK +PN + +G TPL +A + + ++V+ L GA I G+T +H AA
Sbjct: 384 LLDKRANPNAR-ALNGFTPLHIACK-KNRIKVMELLVKYGASIQAITESGLTPIHVAAFM 441
Query: 258 RHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGIADENGWQE 317
H + LL G SP+ + RG T L H A G LL N A +
Sbjct: 442 GHLNIVLLLLQNGASPDVTNIRGETAL-HMAARAGQVEVVRCLLRNGALVDARAREEQTP 500
Query: 318 IHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILLYRGADKDVKN 377
+H A + G ++ ++ LL + A P A +G T LHI A + A +LL GA +
Sbjct: 501 LHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLAT 560
Query: 378 NNGQTPFQVAVIAGNFELGELIRNHR 403
G TP VA G+ ++ +L+ R
Sbjct: 561 KKGFTPLHVAAKYGSLDVAKLLLQRR 586
Score = 79.7 bits (195), Expect = 3e-14
Identities = 79/279 (28%), Positives = 115/279 (41%), Gaps = 42/279 (15%)
Query: 183 FLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDF 242
FL + G DKV L G+D N + + G L LAA+ EG V +++ L G+ +D
Sbjct: 35 FLRAARAGNLDKVVEYLKGGIDINTCNQN-GLNALHLAAK-EGHVGLVQELLGRGSSVDS 92
Query: 243 RARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLF 302
+ G TALH A+ A + L+ G + N + + G TPL+ A + LL
Sbjct: 93 ATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQ-ENHIDVVKYLLE 151
Query: 303 NRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQ------------------- 343
N A A E+G+ + A Q+GH+Q + LL + +
Sbjct: 152 NGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALL 211
Query: 344 ------------------NASGNTALHICALYNKETCARILLYRGADKDVKNNNGQTPFQ 385
SG T LHI A Y A +LL RGA D NG TP
Sbjct: 212 LQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLH 271
Query: 386 VAVIAGNFELGELIRNHREQDVVPFQE--SPKYAARRRG 422
VA GN + +L+ + Q ++ +P + A R G
Sbjct: 272 VASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSG 310
Score = 79.0 bits (193), Expect = 5e-14
Identities = 55/156 (35%), Positives = 80/156 (51%), Gaps = 3/156 (1%)
Query: 198 LLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMTALHKAACA 257
LL+ G + N + G TPL LA+Q EG +++ L GA+I + G+T+LH AA
Sbjct: 648 LLNYGAETNIV-TKQGVTPLHLASQ-EGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQE 705
Query: 258 RHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGIADENGWQE 317
L G + + G TPL A G+ + LL A + +NG+
Sbjct: 706 DKVNVADILTKHGADQDAHTKLGYTPLI-VACHYGNVKMVNFLLKQGANVNAKTKNGYTP 764
Query: 318 IHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHI 353
+HQA Q+GH+ + LL +GA+P A A+GNTAL I
Sbjct: 765 LHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAI 800
Score = 76.3 bits (186), Expect = 3e-13
Identities = 66/229 (28%), Positives = 98/229 (42%), Gaps = 3/229 (1%)
Query: 174 LHTKTGLKKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTL 233
L TK G + G+ D VA+LL + +G TPL +AA + +V L
Sbjct: 558 LATKKGFTPLHVAAKYGSLD-VAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQ-KVALLL 615
Query: 234 CLGGAHIDFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGD 293
GA A++G T LH AA + LL+ G N ++G+TPL H A G
Sbjct: 616 LEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPL-HLASQEGH 674
Query: 294 PRCCELLLFNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHI 353
LLL A + ++ ++G +H A Q + L +GA+ A G T L +
Sbjct: 675 TDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIV 734
Query: 354 CALYNKETCARILLYRGADKDVKNNNGQTPFQVAVIAGNFELGELIRNH 402
Y LL +GA+ + K NG TP A G+ + ++ H
Sbjct: 735 ACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQH 783
Score = 74.7 bits (182), Expect = 9e-13
Identities = 57/203 (28%), Positives = 93/203 (45%), Gaps = 3/203 (1%)
Query: 198 LLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMTALHKAACA 257
LL+KG P + + +G TPL +AA+ + +++ TL GA + + G+T LH A+
Sbjct: 615 LLEKGASP-HATAKNGYTPLHIAAK-KNQMQIASTLLNYGAETNIVTKQGVTPLHLASQE 672
Query: 258 RHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGIADENGWQE 317
H +T LLD G + + + GLT L H A ++L + A + G+
Sbjct: 673 GHTDMVTLLLDKGANIHMSTKSGLTSL-HLAAQEDKVNVADILTKHGADQDAHTKLGYTP 731
Query: 318 IHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILLYRGADKDVKN 377
+ AC G+ + + LL GA A+ +G T LH A +LL GA +
Sbjct: 732 LIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATT 791
Query: 378 NNGQTPFQVAVIAGNFELGELIR 400
NG T +A G + + ++
Sbjct: 792 ANGNTALAIAKRLGYISVVDTLK 814
Score = 65.1 bits (157), Expect = 7e-10
Identities = 67/251 (26%), Positives = 99/251 (39%), Gaps = 40/251 (15%)
Query: 190 GTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMT 249
G ++ V L+ +G + N S +G TPL +AAQ E ++V++ L GA+ DG T
Sbjct: 108 GQAEVVKVLVKEGANINAQ-SQNGFTPLYMAAQ-ENHIDVVKYLLENGANQSTATEDGFT 165
Query: 250 ALHKAACARHCLALTALL--DLGGSP---------------------------------- 273
L A H A+ LL D G
Sbjct: 166 PLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMM 225
Query: 274 -NYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGIADENGWQEIHQACQRGHSQHLEH 332
N G TPL H A G+ LLL A + NG +H A +RG++ ++
Sbjct: 226 VNRTTESGFTPL-HIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKL 284
Query: 333 LLFYGAEPGAQNASGNTALHICALYNKETCARILLYRGADKDVKNNNGQTPFQVAVIAGN 392
LL G + A+ G T LH A + +LL RGA + NG +P +A +
Sbjct: 285 LLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDH 344
Query: 393 FELGELIRNHR 403
E + + H+
Sbjct: 345 VECVKHLLQHK 355
Score = 32.3 bits (72), Expect = 5.2
Identities = 36/137 (26%), Positives = 53/137 (38%), Gaps = 23/137 (16%)
Query: 1913 PERTSSLQRQRLSDDSQSSLLSK--PVSSLFQNWPKPPLPPLPTGTGVSPTAAAAPGATS 1970
P + SL+ +R + S S + +SS + PP+ P SP + +A
Sbjct: 1807 PAASPSLKSERHAPGSPSPKTERHSTLSSSAKTERHPPVSPSSKTEKHSPVSPSAKTERH 1866
Query: 1971 PSASSSSTSTRH--------------LQGVEFEMRPPLL------RRAP-SPSLLPASEH 2009
ASSSS + +H + + E PP+ +R P SPS
Sbjct: 1867 SPASSSSKTEKHSPVSPSTKTERHSPVSSTKTERHPPVSPSGKTDKRPPVSPSGRTEKHP 1926
Query: 2010 KVSPAPRPSSLPILPSG 2026
VSP LP+ PSG
Sbjct: 1927 PVSPGRTEKRLPVSPSG 1943
>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
Length = 4377
Score = 93.6 bits (231), Expect = 2e-18
Identities = 71/226 (31%), Positives = 101/226 (44%), Gaps = 5/226 (2%)
Query: 172 AKLHTKT--GLKKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEV 229
AK+ KT GL + G V LLD+ P + +G +PL +A Q + +
Sbjct: 292 AKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAA-PILSKTKNGLSPLHMATQGD-HLNC 349
Query: 230 IRTLCLGGAHIDFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAM 289
++ L +D D +TALH AA H LLD +PN K G TPL H A
Sbjct: 350 VQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPL-HIAC 408
Query: 290 VGGDPRCCELLLFNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNT 349
+ ELLL + A + E+G IH A GH + L+ +GA P N G T
Sbjct: 409 KKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGET 468
Query: 350 ALHICALYNKETCARILLYRGADKDVKNNNGQTPFQVAVIAGNFEL 395
ALH+ A + R L+ GA + K + QTP ++ G ++
Sbjct: 469 ALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADI 514
Score = 91.3 bits (225), Expect = 9e-18
Identities = 90/303 (29%), Positives = 136/303 (44%), Gaps = 21/303 (6%)
Query: 194 KVAR-LLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMTALH 252
KVA+ LLDK +PN + +G TPL +A + + ++V+ L GA I G+T +H
Sbjct: 381 KVAKVLLDKKANPNAK-ALNGFTPLHIACK-KNRIKVMELLLKHGASIQAVTESGLTPIH 438
Query: 253 KAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGIADE 312
AA H ++ L+ G SPN + RG T L H A G L+ + AQ+ +
Sbjct: 439 VAAFMGHVNIVSQLMHHGASPNTTNVRGETAL-HMAARSGQAEVVRYLVQDGAQVEAKAK 497
Query: 313 NGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILLYRGAD 372
+ +H + + G + ++ LL GA P A SG T LH+ A E A LL GA
Sbjct: 498 DDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGAS 557
Query: 373 KDVKNNNGQTPFQVAVIAGNFELGELIRNHREQDVVPFQESPKYAARRRGPPGTGLTVPP 432
+ G TP VA G E+ L+ + SP A + +GLT P
Sbjct: 558 LSITTKKGFTPLHVAAKYGKLEVANLL--------LQKSASPDAAGK------SGLT--P 601
Query: 433 ALLRANSDT-SMALPDWMVFSAPGAASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASS 491
+ A+ D +AL ++P AA+ P + ++Q TT L G +A +
Sbjct: 602 LHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVT 661
Query: 492 PRG 494
+G
Sbjct: 662 RQG 664
Score = 90.1 bits (222), Expect = 2e-17
Identities = 68/214 (31%), Positives = 100/214 (46%), Gaps = 3/214 (1%)
Query: 188 QLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDG 247
+LG +D V +LL +G PN + SG TPL L+A+ EG +V L GA + + G
Sbjct: 508 RLGKADIVQQLLQQGASPN-AATTSGYTPLHLSAR-EGHEDVAAFLLDHGASLSITTKKG 565
Query: 248 MTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQL 307
T LH AA LL SP+ + GLTPL H A + + LLL A
Sbjct: 566 FTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPL-HVAAHYDNQKVALLLLDQGASP 624
Query: 308 GIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILL 367
A +NG+ +H A ++ LL YGA+ A G ++H+ A +LL
Sbjct: 625 HAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLL 684
Query: 368 YRGADKDVKNNNGQTPFQVAVIAGNFELGELIRN 401
R A+ ++ N +G TP +A + E++ N
Sbjct: 685 GRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVN 718
Score = 87.4 bits (215), Expect = 1e-16
Identities = 68/213 (31%), Positives = 90/213 (42%), Gaps = 3/213 (1%)
Query: 190 GTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMT 249
G D A LLD G + + G TPL +AA+ G +EV L A D + G+T
Sbjct: 543 GHEDVAAFLLDHGASLSI-TTKKGFTPLHVAAKY-GKLEVANLLLQKSASPDAAGKSGLT 600
Query: 250 ALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGI 309
LH AA + LLD G SP+ + G TPL H A LL A
Sbjct: 601 PLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPL-HIAAKKNQMDIATTLLEYGADANA 659
Query: 310 ADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILLYR 369
G +H A Q GH + LL A N SG T LH+ A ++ A +L+ +
Sbjct: 660 VTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQ 719
Query: 370 GADKDVKNNNGQTPFQVAVIAGNFELGELIRNH 402
GA D + G TP V GN ++ + H
Sbjct: 720 GAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQH 752
Score = 86.3 bits (212), Expect = 3e-16
Identities = 76/270 (28%), Positives = 123/270 (45%), Gaps = 18/270 (6%)
Query: 157 KTRVYKQTNLDEKQLAKLHTKTGLKKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETP 216
K R +++ + D K+ + + +L + G +K + G+D N + + G
Sbjct: 24 KKRKHRKRSRDRKKKSDANAS-----YLRAARAGHLEKALDYIKNGVDINICNQN-GLNA 77
Query: 217 LTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMTALHKAACARHCLALTALLDLGGSPNYK 276
L LA++ EG VEV+ L A++D + G TALH A+ A + L+ G + N +
Sbjct: 78 LHLASK-EGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQ 136
Query: 277 DRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFY 336
+ G TPL+ A + LL N A +A E+G+ + A Q+GH Q + LL
Sbjct: 137 SQNGFTPLYMAAQ-ENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLL-- 193
Query: 337 GAEPGAQNASGNTALHICALYNKETCARILLYRGADKDVKNNNGQTPFQVAVIAGNFELG 396
E + ALHI A + A +LL + DV++ +G TP +A GN +
Sbjct: 194 --ENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVA 251
Query: 397 ELIRNHREQDVVPFQE----SPKYAARRRG 422
L+ N V F +P + A +RG
Sbjct: 252 TLLLNRAA--AVDFTARNDITPLHVASKRG 279
Score = 85.1 bits (209), Expect = 7e-16
Identities = 59/188 (31%), Positives = 88/188 (46%), Gaps = 2/188 (1%)
Query: 215 TPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMTALHKAACARHCLALTALLDLGGSPN 274
TPL +A++ G+ +++ L GA ID + RDG+T LH A + H + LLD
Sbjct: 270 TPLHVASK-RGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPIL 328
Query: 275 YKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGIADENGWQEIHQACQRGHSQHLEHLL 334
K + GL+PL H A G C +LLL + + + +H A GH + + LL
Sbjct: 329 SKTKNGLSPL-HMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLL 387
Query: 335 FYGAEPGAQNASGNTALHICALYNKETCARILLYRGADKDVKNNNGQTPFQVAVIAGNFE 394
A P A+ +G T LHI N+ +LL GA +G TP VA G+
Sbjct: 388 DKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVN 447
Query: 395 LGELIRNH 402
+ + +H
Sbjct: 448 IVSQLMHH 455
Score = 77.4 bits (189), Expect = 1e-13
Identities = 67/227 (29%), Positives = 91/227 (40%), Gaps = 3/227 (1%)
Query: 166 LDEKQLAKLHTKTGLKKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEG 225
LD + TK G + G + LL K P+ SG TPL +AA +
Sbjct: 552 LDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGK-SGLTPLHVAAHYDN 610
Query: 226 SVEVIRTLCLGGAHIDFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLF 285
+V L GA A++G T LH AA T LL+ G N R+G+ +
Sbjct: 611 Q-KVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASV- 668
Query: 286 HTAMVGGDPRCCELLLFNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNA 345
H A G LLL A + +++++G +H A Q E L+ GA AQ
Sbjct: 669 HLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTK 728
Query: 346 SGNTALHICALYNKETCARILLYRGADKDVKNNNGQTPFQVAVIAGN 392
G T LH+ Y LL A + K NG TP A G+
Sbjct: 729 MGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGH 775
Score = 73.2 bits (178), Expect = 3e-12
Identities = 57/219 (26%), Positives = 100/219 (45%), Gaps = 3/219 (1%)
Query: 198 LLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMTALHKAACA 257
LLD+G P + + +G TPL +AA+ + +++ TL GA + R G+ ++H AA
Sbjct: 617 LLDQGASP-HAAAKNGYTPLHIAAK-KNQMDIATTLLEYGADANAVTRQGIASVHLAAQE 674
Query: 258 RHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGIADENGWQE 317
H ++ LL + N ++ GLTPL H A E+L+ A + + G+
Sbjct: 675 GHVDMVSLLLGRNANVNLSNKSGLTPL-HLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTP 733
Query: 318 IHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILLYRGADKDVKN 377
+H C G+ + + LL + A+ A+ +G T LH A +LL A +
Sbjct: 734 LHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELT 793
Query: 378 NNGQTPFQVAVIAGNFELGELIRNHREQDVVPFQESPKY 416
NG T +A G + + ++ E+ + + K+
Sbjct: 794 VNGNTALGIARRLGYISVVDTLKIVTEETMTTTTVTEKH 832
Score = 71.2 bits (173), Expect = 1e-11
Identities = 57/187 (30%), Positives = 86/187 (45%), Gaps = 6/187 (3%)
Query: 213 GETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMTALHKAACARHCLALTALLDLGGS 272
G T L +A+ G EV++ L GA+++ ++++G T L+ AA H + LLD G S
Sbjct: 107 GNTALHIASLA-GQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGAS 165
Query: 273 PNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGIADENGWQEIHQACQRGHSQHLEH 332
+ G TPL A+ G + LLL N + + +H A ++ ++
Sbjct: 166 QSLATEDGFTPL-AVALQQGHDQVVSLLLENDTKGKVR----LPALHIAARKDDTKAAAL 220
Query: 333 LLFYGAEPGAQNASGNTALHICALYNKETCARILLYRGADKDVKNNNGQTPFQVAVIAGN 392
LL ++ SG T LHI A Y A +LL R A D N TP VA GN
Sbjct: 221 LLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGN 280
Query: 393 FELGELI 399
+ +L+
Sbjct: 281 ANMVKLL 287
Score = 70.9 bits (172), Expect = 1e-11
Identities = 51/161 (31%), Positives = 79/161 (49%), Gaps = 3/161 (1%)
Query: 193 DKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMTALH 252
D LL+ G D N + G + LAAQ EG V+++ L A+++ + G+T LH
Sbjct: 645 DIATTLLEYGADANAV-TRQGIASVHLAAQ-EGHVDMVSLLLGRNANVNLSNKSGLTPLH 702
Query: 253 KAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGIADE 312
AA L++ G + + + G TPL H G+ + LL + A++ +
Sbjct: 703 LAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPL-HVGCHYGNIKIVNFLLQHSAKVNAKTK 761
Query: 313 NGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHI 353
NG+ +HQA Q+GH+ + LL A P +GNTAL I
Sbjct: 762 NGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGI 802
Score = 68.6 bits (166), Expect = 7e-11
Identities = 68/242 (28%), Positives = 97/242 (40%), Gaps = 32/242 (13%)
Query: 190 GTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMT 249
G ++ V L+ G + N S +G TPL +AAQ E +EV++ L GA DG T
Sbjct: 118 GQAEVVKVLVTNGANVNAQ-SQNGFTPLYMAAQ-ENHLEVVKFLLDNGASQSLATEDGFT 175
Query: 250 -----------------------------ALHKAACARHCLALTALLDLGGSPNYKDRRG 280
ALH AA A LL + + + + G
Sbjct: 176 PLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSG 235
Query: 281 LTPLFHTAMVGGDPRCCELLLFNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEP 340
TPL H A G+ LLL A + N +H A +RG++ ++ LL GA+
Sbjct: 236 FTPL-HIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKI 294
Query: 341 GAQNASGNTALHICALYNKETCARILLYRGADKDVKNNNGQTPFQVAVIAGNFELGELIR 400
A+ G T LH A E +LL R A K NG +P +A + +L+
Sbjct: 295 DAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLL 354
Query: 401 NH 402
H
Sbjct: 355 QH 356
Score = 33.1 bits (74), Expect = 3.0
Identities = 74/325 (22%), Positives = 127/325 (39%), Gaps = 35/325 (10%)
Query: 1660 APQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVA 1719
AP P P + + S + S PL++I S ST S + + G S + + VA
Sbjct: 1509 APITVPGPAKSGFTSLSSSSSNTPSASPLKSIWSVSTPSPIKSTLGASTTSSVKSISDVA 1568
Query: 1720 SGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGPSGGLRDP 1779
S T + + + PY Q+ + + R A+ + L+ GL
Sbjct: 1569 SPIRSFRTMSSPIK------TVVSQSPYNIQVSSGTLARAPAVTEATPLK-----GLASN 1617
Query: 1780 VTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLP 1839
T +S T VT AG+ LL + + P P + + + +SSLP K +
Sbjct: 1618 STFSSRTSPVTTAGS--LLERSSITMTP-------PASPKSNINMY----SSSLPFKSII 1664
Query: 1840 WEEGP--GPPPPPLPGPLAQPQASALATVKASIISELSSKLQQFGGS---SAAGGALPWA 1894
P P + P+ + +++ K ++ S LSS ++Q G + G++
Sbjct: 1665 TSAAPLISSPLKSVVSPV-KSAVDVISSAKITMASSLSSPVKQMPGHAEVALVNGSISPL 1723
Query: 1895 RGGSGGGGDSHHGGASYVPERTSSLQRQRLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPT 1954
+ S + + + E+ SS S S S + V +F P PL +
Sbjct: 1724 KYPSSSTLINGCKATATLQEKISSATN---SVSSVVSAATDTVEKVFSTTTAMPFSPLRS 1780
Query: 1955 GTGVSPTAAAAPGATSPSASSSSTS 1979
+P+A + +PSAS+ TS
Sbjct: 1781 YVSAAPSAFQS--LRTPSASALYTS 1803
Score = 32.0 bits (71), Expect = 6.8
Identities = 21/82 (25%), Positives = 33/82 (40%), Gaps = 7/82 (8%)
Query: 1131 SPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGG 1190
S +P++PQ + + +PIP +I + + S S P TQPE
Sbjct: 2134 SEKTPSAPQSAESTGPKPLFHEVPIPPVITETRTEVVHVIRSYDPSAGDVPQTQPEEP-- 2191
Query: 1191 GGGGGSSPSPAPAMSPVPPSPS 1212
SP P+P + P P+
Sbjct: 2192 -----VSPKPSPTFMELEPKPT 2208
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.133 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 125,826,285
Number of Sequences: 37866
Number of extensions: 9650799
Number of successful extensions: 201438
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1556
Number of HSP's successfully gapped in prelim test: 3042
Number of HSP's that attempted gapping in prelim test: 49807
Number of HSP's gapped (non-prelim): 82420
length of query: 2161
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2043
effective length of database: 13,779,330
effective search space: 28151171190
effective search space used: 28151171190
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.