Guide to the Human Genome
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Name: SHANK2 Sequence: fasta or formatted (1849aa) NCBI GI: 226817313
Description:

SH3 and multiple ankyrin repeat domains 2 isoform 1

Referenced in:

Actin and Related Proteins
Ankyrin Family
Synapses
Non-Receptor Tyrosine Kinase Pathways

Other entries for this name:
alt prot [281aa] SH3 and multiple ankyrin repeat domains 2 isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.2        151           3
 C cysteine            1.0         19           2
 D aspartate           5.9        109           2
 E glutamate           6.8        125           3
 F phenylalanine       2.8         52           1
 G glycine             6.2        115           2
 H histidine           1.8         34           2
 I isoleucine          3.7         68           2
 K lysine              5.9        110           3
 L leucine             8.0        148           3
 M methionine          2.1         39           2
 N asparagine          3.6         67           2
 P proline            10.1        187           5
 Q glutamine           3.8         70           2
 R arginine            5.9        110           4
 S serine              9.8        182           3
 T threonine           5.9        109           2
 V valine              5.8        107           2
 W tryptophan          0.5         10           1
 Y tyrosine            2.0         37           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   SH3 and multiple ankyrin repeat domains 2 isoform 1... 
SHANK3                0.357   SH3 and multiple ankyrin repeat domains 3 
SHANK1                0.335   SH3 and multiple ankyrin repeat domains 1 
LOC100133890          0.199   PREDICTED: similar to Shank2E 
SHANK2                0.119   SH3 and multiple ankyrin repeat domains 2 isoform 2 ...
ANK1                  0.020   ankyrin 1 isoform 9 
ANK1                  0.020   ankyrin 1 isoform 1 
ANK1                  0.020   ankyrin 1 isoform 3 
ANK1                  0.020   ankyrin 1 isoform 2 
ANK1                  0.020   ankyrin 1 isoform 4 
ANKK1                 0.019   ankyrin repeat and kinase domain containing 1 
ANK2                  0.019   ankyrin 2 isoform 3 
ANK2                  0.019   ankyrin 2 isoform 2 
ANK2                  0.019   ankyrin 2 isoform 1 
ANK3                  0.019   ankyrin 3 isoform 1 
EHMT1                 0.017   euchromatic histone-lysine N-methyltransferase 1 is...
ANKRD28               0.017   ankyrin repeat domain 28 
ANKRD1                0.016   cardiac ankyrin repeat protein 
HACE1                 0.016   HECT domain and ankyrin repeat containing, E3 ubiqu...
ANKRD52               0.016   ankyrin repeat domain 52 
NOTCH1                0.016   notch1 preproprotein 
ANKRD6                0.016   ankyrin repeat domain 6 
NOTCH3                0.016   Notch homolog 3 
NOTCH4                0.015   notch4 preproprotein 
EHMT2                 0.015   euchromatic histone-lysine N-methyltransferase 2 is...
EHMT2                 0.015   euchromatic histone-lysine N-methyltransferase 2 is...
ANKRD50               0.015   ankyrin repeat domain 50 
ANKRD44               0.015   ankyrin repeat domain 44 
ANKRD27               0.015   ankyrin repeat domain 27 (VPS9 domain) 
ASB2                  0.014   ankyrin repeat and SOCS box-containing protein 2 [Ho...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
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