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Search of human proteins with 24797076
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24797076 major histocompatibility complex, class II, DP beta
1 precursor [Homo sapiens]
(258 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24797076 major histocompatibility complex, class II, DP beta ... 525 e-149
gi|239758095 PREDICTED: similar to major histocompatibility comp... 342 2e-94
gi|239740749 PREDICTED: similar to major histocompatibility comp... 342 2e-94
gi|239748788 PREDICTED: similar to major histocompatibility comp... 339 1e-93
gi|239740863 PREDICTED: similar to major histocompatibility comp... 339 1e-93
gi|239513955 PREDICTED: similar to major histocompatibility comp... 339 1e-93
gi|169168591 PREDICTED: similar to major histocompatibility comp... 335 2e-92
gi|239740920 PREDICTED: similar to major histocompatibility comp... 329 2e-90
gi|239740918 PREDICTED: similar to major histocompatibility comp... 329 2e-90
gi|155030211 major histocompatibility complex, class II, DR beta... 328 2e-90
gi|150418002 major histocompatibility complex, class II, DQ beta... 327 6e-90
gi|239740745 PREDICTED: similar to HLA class II histocompatibili... 324 4e-89
gi|239740695 PREDICTED: similar to HLA class II histocompatibili... 324 4e-89
gi|239740853 PREDICTED: similar to major histocompatibility comp... 318 2e-87
gi|239748820 PREDICTED: hypothetical protein XP_002346811 [Homo ... 318 4e-87
gi|239740855 PREDICTED: similar to major histocompatibility comp... 316 1e-86
gi|17986005 major histocompatibility complex, class II, DR beta ... 315 2e-86
gi|239748785 PREDICTED: similar to HLA class II histocompatibili... 314 4e-86
gi|239740857 PREDICTED: similar to major histocompatibility comp... 313 9e-86
gi|18641375 major histocompatibility complex, class II, DR beta ... 313 9e-86
gi|239740743 PREDICTED: similar to HLA class II histocompatibili... 313 1e-85
gi|239740693 PREDICTED: similar to HLA class II histocompatibili... 313 1e-85
gi|52630344 major histocompatibility complex, class II, DR beta ... 308 3e-84
gi|239740859 PREDICTED: similar to major histocompatibility comp... 308 3e-84
gi|239758090 PREDICTED: major histocompatibility complex, class ... 300 1e-81
gi|239758092 PREDICTED: similar to HLA class II histocompatibili... 275 3e-74
gi|4504403 major histocompatibility complex, class II, DO beta p... 273 8e-74
gi|169217452 PREDICTED: similar to HLA class II histocompatibili... 259 2e-69
gi|169168671 PREDICTED: similar to MHC class II antigen [Homo sa... 177 1e-44
gi|169168589 PREDICTED: similar to MHC class II antigen [Homo sa... 118 6e-27
>gi|24797076 major histocompatibility complex, class II, DP beta 1
precursor [Homo sapiens]
Length = 258
Score = 525 bits (1353), Expect = e-149
Identities = 258/258 (100%), Positives = 258/258 (100%)
Query: 1 MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQRFLERYIYN 60
MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQRFLERYIYN
Sbjct: 1 MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQRFLERYIYN 60
Query: 61 REEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTLQR 120
REEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTLQR
Sbjct: 61 REEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTLQR 120
Query: 121 RVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNGDW 180
RVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNGDW
Sbjct: 121 RVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNGDW 180
Query: 181 TFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLIIC 240
TFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLIIC
Sbjct: 181 TFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLIIC 240
Query: 241 GVGIFMHRRSKKVQRGSA 258
GVGIFMHRRSKKVQRGSA
Sbjct: 241 GVGIFMHRRSKKVQRGSA 258
>gi|239758095 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 [Homo sapiens]
Length = 281
Score = 342 bits (877), Expect = 2e-94
Identities = 167/251 (66%), Positives = 197/251 (78%), Gaps = 2/251 (0%)
Query: 4 LQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQR--FLERYIYNR 61
L++ R +T +L +L T V +GR +PE++++Q + CY NGT+R + R IYNR
Sbjct: 7 LRIPGGLRAATVTLMLSMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNR 66
Query: 62 EEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTLQRR 121
EE RFDSDVGEFRAVT LG PAAEYWNSQKDILE KRA DR+CRHNY+L TLQRR
Sbjct: 67 EEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRR 126
Query: 122 VQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNGDWT 181
V+P V +SPS+ L HHNLLVC VTDFYP I+VRWF NGQEETAGVVST LIRNGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNGQEETAGVVSTPLIRNGDWT 186
Query: 182 FQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLIICG 241
FQILVMLEMTPQ+GDVYTC VEH SL SP+TVEW+AQS+SA+SK L+G GGFVLGLI G
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246
Query: 242 VGIFMHRRSKK 252
+G+ +H RS+K
Sbjct: 247 LGLIIHHRSQK 257
>gi|239740749 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 [Homo sapiens]
Length = 281
Score = 342 bits (877), Expect = 2e-94
Identities = 167/251 (66%), Positives = 197/251 (78%), Gaps = 2/251 (0%)
Query: 4 LQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQR--FLERYIYNR 61
L++ R +T +L +L T V +GR +PE++++Q + CY NGT+R + R IYNR
Sbjct: 7 LRIPGGLRAATVTLMLSMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNR 66
Query: 62 EEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTLQRR 121
EE RFDSDVGEFRAVT LG PAAEYWNSQKDILE KRA DR+CRHNY+L TLQRR
Sbjct: 67 EEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRR 126
Query: 122 VQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNGDWT 181
V+P V +SPS+ L HHNLLVC VTDFYP I+VRWF NGQEETAGVVST LIRNGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNGQEETAGVVSTPLIRNGDWT 186
Query: 182 FQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLIICG 241
FQILVMLEMTPQ+GDVYTC VEH SL SP+TVEW+AQS+SA+SK L+G GGFVLGLI G
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246
Query: 242 VGIFMHRRSKK 252
+G+ +H RS+K
Sbjct: 247 LGLIIHHRSQK 257
>gi|239748788 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 isoform 2 [Homo sapiens]
Length = 281
Score = 339 bits (870), Expect = 1e-93
Identities = 166/251 (66%), Positives = 196/251 (78%), Gaps = 2/251 (0%)
Query: 4 LQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQR--FLERYIYNR 61
L++ R +T +L +L T V +GR +PE++++Q + CY NGT+R + R IYNR
Sbjct: 7 LRIPGGLRVATVTLMLAMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNR 66
Query: 62 EEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTLQRR 121
EE RFDSDVGEFRAVT LG PAAEYWNSQKDILE KRA DR+CRHNY+L TLQRR
Sbjct: 67 EEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRR 126
Query: 122 VQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNGDWT 181
V+P V +SPS+ L HHNLLVC VTDFYP I+VRWF N QEETAGVVST LIRNGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWT 186
Query: 182 FQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLIICG 241
FQILVMLEMTPQ+GDVYTC VEH SL SP+TVEW+AQS+SA+SK L+G GGFVLGLI G
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246
Query: 242 VGIFMHRRSKK 252
+G+ +H RS+K
Sbjct: 247 LGLIIHHRSQK 257
>gi|239740863 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 [Homo sapiens]
Length = 281
Score = 339 bits (870), Expect = 1e-93
Identities = 166/251 (66%), Positives = 196/251 (78%), Gaps = 2/251 (0%)
Query: 4 LQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQR--FLERYIYNR 61
L++ R +T +L +L T V +GR +PE++++Q + CY NGT+R + R IYNR
Sbjct: 7 LRIPGGLRAATVTLMLSMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNR 66
Query: 62 EEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTLQRR 121
EE RFDSDVGEFRAVT LG PAAEYWNSQKDILE KRA DR+CRHNY+L TLQRR
Sbjct: 67 EEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRR 126
Query: 122 VQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNGDWT 181
V+P V +SPS+ L HHNLLVC VTDFYP I+VRWF N QEETAGVVST LIRNGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWT 186
Query: 182 FQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLIICG 241
FQILVMLEMTPQ+GDVYTC VEH SL SP+TVEW+AQS+SA+SK L+G GGFVLGLI G
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246
Query: 242 VGIFMHRRSKK 252
+G+ +H RS+K
Sbjct: 247 LGLIIHHRSQK 257
>gi|239513955 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 [Homo sapiens]
Length = 281
Score = 339 bits (870), Expect = 1e-93
Identities = 166/251 (66%), Positives = 196/251 (78%), Gaps = 2/251 (0%)
Query: 4 LQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQR--FLERYIYNR 61
L++ R +T +L +L T V +GR +PE++++Q + CY NGT+R + R IYNR
Sbjct: 7 LRIPGGLRAATVTLMLSMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNR 66
Query: 62 EEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTLQRR 121
EE RFDSDVGEFRAVT LG PAAEYWNSQKDILE KRA DR+CRHNY+L TLQRR
Sbjct: 67 EEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRR 126
Query: 122 VQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNGDWT 181
V+P V +SPS+ L HHNLLVC VTDFYP I+VRWF N QEETAGVVST LIRNGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWT 186
Query: 182 FQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLIICG 241
FQILVMLEMTPQ+GDVYTC VEH SL SP+TVEW+AQS+SA+SK L+G GGFVLGLI G
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246
Query: 242 VGIFMHRRSKK 252
+G+ +H RS+K
Sbjct: 247 LGLIIHHRSQK 257
>gi|169168591 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 isoform 1 [Homo sapiens]
Length = 261
Score = 335 bits (860), Expect = 2e-92
Identities = 163/251 (64%), Positives = 196/251 (78%), Gaps = 2/251 (0%)
Query: 4 LQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQRF--LERYIYNR 61
L++ R +T +L +L T V +GR +PE+++FQ + CY NGT+R + RYIYNR
Sbjct: 7 LRIPGGLRVATVTLMLAMLSTPVAEGRDSPEDFVFQFKGMCYFTNGTERVRGVTRYIYNR 66
Query: 62 EEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTLQRR 121
EE+ARFDSDVG +RAVT LG PAAEYWNSQK++LE RA D +CRHNY+L TLQRR
Sbjct: 67 EEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRASVDTVCRHNYQLELRTTLQRR 126
Query: 122 VQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNGDWT 181
V+P V +SPS+ L HHNLLVC VTDFYP I+VRWF N QEETAGVVST LIRNGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWT 186
Query: 182 FQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLIICG 241
FQILVMLEMTPQ+GDVYTC VEH SL SP+TVEW+AQS+SA+SK L+G GGFVLGLI G
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246
Query: 242 VGIFMHRRSKK 252
+G+ +H RS+K
Sbjct: 247 LGLIIHHRSQK 257
>gi|239740920 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 2 [Homo sapiens]
Length = 261
Score = 329 bits (843), Expect = 2e-90
Identities = 159/251 (63%), Positives = 194/251 (77%), Gaps = 2/251 (0%)
Query: 4 LQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQRF--LERYIYNR 61
L++ R +T +L +L T V +GR +PE++++Q + CY NGT+R + RYIYNR
Sbjct: 7 LRIPGGLRVATVTLMLAMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRGVTRYIYNR 66
Query: 62 EEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTLQRR 121
EE+ARFDSDVG +RAVT LG PAAEYWNSQK++LE RA D +CRHNY+L TLQRR
Sbjct: 67 EEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCRHNYQLELRTTLQRR 126
Query: 122 VQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNGDWT 181
V+P V +SPS+ L HHNLLVC VTDFYP I+VRWF N QEET GVVST LIRNGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPLIRNGDWT 186
Query: 182 FQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLIICG 241
FQILVMLEMTPQ+GDVYTC VEH SL +P+ VEW+AQS+SA+SK L+G GGFVLGLI G
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246
Query: 242 VGIFMHRRSKK 252
+G+ +H RS+K
Sbjct: 247 LGLIIHHRSQK 257
>gi|239740918 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 1 [Homo sapiens]
Length = 281
Score = 329 bits (843), Expect = 2e-90
Identities = 159/251 (63%), Positives = 194/251 (77%), Gaps = 2/251 (0%)
Query: 4 LQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQRF--LERYIYNR 61
L++ R +T +L +L T V +GR +PE++++Q + CY NGT+R + RYIYNR
Sbjct: 7 LRIPGGLRVATVTLMLAMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRGVTRYIYNR 66
Query: 62 EEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTLQRR 121
EE+ARFDSDVG +RAVT LG PAAEYWNSQK++LE RA D +CRHNY+L TLQRR
Sbjct: 67 EEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCRHNYQLELRTTLQRR 126
Query: 122 VQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNGDWT 181
V+P V +SPS+ L HHNLLVC VTDFYP I+VRWF N QEET GVVST LIRNGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPLIRNGDWT 186
Query: 182 FQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLIICG 241
FQILVMLEMTPQ+GDVYTC VEH SL +P+ VEW+AQS+SA+SK L+G GGFVLGLI G
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246
Query: 242 VGIFMHRRSKK 252
+G+ +H RS+K
Sbjct: 247 LGLIIHHRSQK 257
>gi|155030211 major histocompatibility complex, class II, DR beta 1
precursor [Homo sapiens]
Length = 266
Score = 328 bits (842), Expect = 2e-90
Identities = 161/258 (62%), Positives = 197/258 (76%), Gaps = 2/258 (0%)
Query: 1 MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQR--FLERYI 58
M+ L++ ALT LMVL + + T +L+Q ++EC+ FNGT+R FL+RY
Sbjct: 1 MVCLKLPGGSCMTALTVTLMVLSSPLALSGDTRPRFLWQPKRECHFFNGTERVRFLDRYF 60
Query: 59 YNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTL 118
YN+EE RFDSDVGEFRAVTELGRP AEYWNSQKDILE+ RA D CRHNY + T+
Sbjct: 61 YNQEESVRFDSDVGEFRAVTELGRPDAEYWNSQKDILEQARAAVDTYCRHNYGVVESFTV 120
Query: 119 QRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNG 178
QRRVQP+V V PSK PLQHHNLLVC V+ FYPGSI+VRWFLNGQEE AG+VST LI+NG
Sbjct: 121 QRRVQPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFLNGQEEKAGMVSTGLIQNG 180
Query: 179 DWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLI 238
DWTFQ LVMLE P+ G+VYTCQVEH S+ SP+TVEW+A+S+SA+SK L+G GGFVLGL+
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL 240
Query: 239 ICGVGIFMHRRSKKVQRG 256
G G+F++ R++K G
Sbjct: 241 FLGAGLFIYFRNQKGHSG 258
>gi|150418002 major histocompatibility complex, class II, DQ beta 1
precursor [Homo sapiens]
Length = 261
Score = 327 bits (838), Expect = 6e-90
Identities = 159/251 (63%), Positives = 195/251 (77%), Gaps = 2/251 (0%)
Query: 4 LQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQR--FLERYIYNR 61
L++ R +T +L +L + + +GR +PE+++FQ + CY NGT+R + RYIYNR
Sbjct: 7 LRIPGDLRVATVTLMLAMLSSLLAEGRDSPEDFVFQFKGMCYFTNGTERVRLVTRYIYNR 66
Query: 62 EEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTLQRR 121
EE+ARFDSDVG +RAVT GRP AEYWNSQK++LE RA D +CRHNYE+ LQRR
Sbjct: 67 EEYARFDSDVGVYRAVTPQGRPDAEYWNSQKEVLEGTRAELDTVCRHNYEVAFRGILQRR 126
Query: 122 VQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNGDWT 181
V+P V +SPS+ L HHNLLVC VTDFYPG I+VRWF N QEETAGVVST LIRNGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPGQIKVRWFRNDQEETAGVVSTPLIRNGDWT 186
Query: 182 FQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLIICG 241
FQILVMLEMTPQ+GDVYTC VEH SL SP+TVEW+AQS+SA+SK L+G GGFVLGLI G
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGVGGFVLGLIFLG 246
Query: 242 VGIFMHRRSKK 252
+G+ + +RS+K
Sbjct: 247 LGLIIRQRSQK 257
>gi|239740745 PREDICTED: similar to HLA class II histocompatibility
antigen, DRB1-7 beta chain isoform 1 [Homo sapiens]
Length = 266
Score = 324 bits (831), Expect = 4e-89
Identities = 158/258 (61%), Positives = 195/258 (75%), Gaps = 2/258 (0%)
Query: 1 MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQR--FLERYI 58
M+ L++ ALT LMVL + + T +L+QG+ +C+ FNGT+R FLER
Sbjct: 1 MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60
Query: 59 YNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTL 118
YN+EEF RFDSDVGE+RAVTELGRP AE WNSQKDILE++R D +CRHNY +G T+
Sbjct: 61 YNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQKDILEDRRGQVDTVCRHNYGVGESFTV 120
Query: 119 QRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNG 178
QRRV P V V P+K PLQHHNLLVC V+ FYPGSI+VRWF NGQEE AGVVST LI+NG
Sbjct: 121 QRRVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180
Query: 179 DWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLI 238
DWTFQ LVMLE P+ G+VYTCQVEH S+ SP+TVEW+A+S+SA+SK L+G GGFVLGL+
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLL 240
Query: 239 ICGVGIFMHRRSKKVQRG 256
G G+F++ R++K G
Sbjct: 241 FLGAGLFIYFRNQKGHSG 258
>gi|239740695 PREDICTED: similar to HLA class II histocompatibility
antigen, DRB1-7 beta chain isoform 1 [Homo sapiens]
Length = 266
Score = 324 bits (831), Expect = 4e-89
Identities = 158/258 (61%), Positives = 195/258 (75%), Gaps = 2/258 (0%)
Query: 1 MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQR--FLERYI 58
M+ L++ ALT LMVL + + T +L+QG+ +C+ FNGT+R FLER
Sbjct: 1 MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60
Query: 59 YNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTL 118
YN+EEF RFDSDVGE+RAVTELGRP AE WNSQKDILE++R D +CRHNY +G T+
Sbjct: 61 YNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQKDILEDRRGQVDTVCRHNYGVGESFTV 120
Query: 119 QRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNG 178
QRRV P V V P+K PLQHHNLLVC V+ FYPGSI+VRWF NGQEE AGVVST LI+NG
Sbjct: 121 QRRVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180
Query: 179 DWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLI 238
DWTFQ LVMLE P+ G+VYTCQVEH S+ SP+TVEW+A+S+SA+SK L+G GGFVLGL+
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLL 240
Query: 239 ICGVGIFMHRRSKKVQRG 256
G G+F++ R++K G
Sbjct: 241 FLGAGLFIYFRNQKGHSG 258
>gi|239740853 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 3 isoform 2 [Homo sapiens]
Length = 266
Score = 318 bits (816), Expect = 2e-87
Identities = 156/258 (60%), Positives = 193/258 (74%), Gaps = 2/258 (0%)
Query: 1 MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQR--FLERYI 58
M+ L++ ALT LMVL + + T +L + EC+ FNGT+R FLER+
Sbjct: 1 MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELLKSECHFFNGTERVRFLERHF 60
Query: 59 YNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTL 118
+N+EE+ARFDSDVGE+RAV ELGRP AEYWNSQKD+LE+KR D CRHNY +G T+
Sbjct: 61 HNQEEYARFDSDVGEYRAVRELGRPDAEYWNSQKDLLEQKRGQVDNYCRHNYGVGESFTV 120
Query: 119 QRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNG 178
QRRV P+V V P+K PLQHHNLLVC V+ FYPGSI+VRWF NGQEE AGVVST LI+NG
Sbjct: 121 QRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180
Query: 179 DWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLI 238
DWTFQ LVMLE P+ G+VYTCQVEH S+ SP+TVEW A+S+SA+SK L+G GGFVLGL+
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWSARSESAQSKMLSGVGGFVLGLL 240
Query: 239 ICGVGIFMHRRSKKVQRG 256
G G+F++ R++K G
Sbjct: 241 FLGAGLFIYFRNQKGHSG 258
>gi|239748820 PREDICTED: hypothetical protein XP_002346811 [Homo
sapiens]
Length = 266
Score = 318 bits (814), Expect = 4e-87
Identities = 156/258 (60%), Positives = 191/258 (74%), Gaps = 2/258 (0%)
Query: 1 MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQR--FLERYI 58
M+ L++ LT LMVL + + T +L + + EC+ FNGT+R LERY
Sbjct: 1 MVCLRLPGGSCMAVLTVTLMVLSSPLALAGDTRPRFLEEVKFECHFFNGTERVRLLERYF 60
Query: 59 YNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTL 118
+N+EE RFDSDVGEFRAVTELGRP AEYWNSQKD+LE++RA D CRHNY +G T+
Sbjct: 61 HNQEENVRFDSDVGEFRAVTELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTV 120
Query: 119 QRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNG 178
QRRV P+V V PSK PLQHHNLLVC V+ FYPGSI+VRWF NGQEE GVVST LI NG
Sbjct: 121 QRRVHPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNG 180
Query: 179 DWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLI 238
DWTFQ LVMLE P+ G+VYTCQVEH S+ SP+TVEW+A+S+SA+SK L+G GGFVLGL+
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL 240
Query: 239 ICGVGIFMHRRSKKVQRG 256
G G+F++ R++K G
Sbjct: 241 FLGAGLFIYFRNQKGHSG 258
>gi|239740855 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 3 isoform 1 [Homo sapiens]
Length = 267
Score = 316 bits (810), Expect = 1e-86
Identities = 156/259 (60%), Positives = 195/259 (75%), Gaps = 3/259 (1%)
Query: 1 MMVLQVSAAPRTVALTALLMVLLTSVV-QGRATPENYLFQGRQECYAFNGTQR--FLERY 57
M+ L++ ALT LMVL + + G ++ L+ + EC+ FNGT+R FLER+
Sbjct: 1 MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRRKSTLWLLKSECHFFNGTERVRFLERH 60
Query: 58 IYNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMT 117
+N+EE+ARFDSDVGE+RAV ELGRP AEYWNSQKD+LE+KR D CRHNY +G T
Sbjct: 61 FHNQEEYARFDSDVGEYRAVRELGRPDAEYWNSQKDLLEQKRGQVDNYCRHNYGVGESFT 120
Query: 118 LQRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRN 177
+QRRV P+V V P+K PLQHHNLLVC V+ FYPGSI+VRWF NGQEE AGVVST LI+N
Sbjct: 121 VQRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQN 180
Query: 178 GDWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGL 237
GDWTFQ LVMLE P+ G+VYTCQVEH S+ SP+TVEW A+S+SA+SK L+G GGFVLGL
Sbjct: 181 GDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWSARSESAQSKMLSGVGGFVLGL 240
Query: 238 IICGVGIFMHRRSKKVQRG 256
+ G G+F++ R++K G
Sbjct: 241 LFLGAGLFIYFRNQKGHSG 259
>gi|17986005 major histocompatibility complex, class II, DR beta 3
precursor [Homo sapiens]
Length = 266
Score = 315 bits (807), Expect = 2e-86
Identities = 154/258 (59%), Positives = 192/258 (74%), Gaps = 2/258 (0%)
Query: 1 MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQR--FLERYI 58
M+ L++ ALT LMVL + + T +L + EC+ FNGT+R +L+RY
Sbjct: 1 MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYF 60
Query: 59 YNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTL 118
+N+EEF RFDSDVGE+RAVTELGRP AE WNSQKD+LE+KR D CRHNY +G T+
Sbjct: 61 HNQEEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTV 120
Query: 119 QRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNG 178
QRRV P+V V P+K PLQHHNLLVC V+ FYPGSI+VRWF NGQEE AGVVST LI+NG
Sbjct: 121 QRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180
Query: 179 DWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLI 238
DWTFQ LVMLE P+ G+VYTCQVEH S+ S +TVEW+A+S+SA+SK L+G GGFVLGL+
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLGLL 240
Query: 239 ICGVGIFMHRRSKKVQRG 256
G G+F++ R++K G
Sbjct: 241 FLGAGLFIYFRNQKGHSG 258
>gi|239748785 PREDICTED: similar to HLA class II histocompatibility
antigen, DRB1-9 beta chain [Homo sapiens]
Length = 266
Score = 314 bits (805), Expect = 4e-86
Identities = 156/258 (60%), Positives = 191/258 (74%), Gaps = 2/258 (0%)
Query: 1 MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQR--FLERYI 58
M+ L++ ALT LMVL + + T +L Q + EC+ FNGT+R +L R I
Sbjct: 1 MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLKQDKFECHFFNGTERVRYLHRGI 60
Query: 59 YNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTL 118
YN+EE RFDSDVGE+RAVTELGRP AE WNSQKD LE +RA D +CRHNY +G T+
Sbjct: 61 YNQEENVRFDSDVGEYRAVTELGRPVAESWNSQKDFLERRRAEVDTVCRHNYGVGESFTV 120
Query: 119 QRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNG 178
QRRV P V V P+K PLQHHNLLVC V+ FYPGSI+VRWF NGQEE AGVVST LI+NG
Sbjct: 121 QRRVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180
Query: 179 DWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLI 238
DWTFQ LVMLE P+ G+VYTCQVEH S+ SP+TVEW+A+S+SA+SK L+G GGFVLGL+
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLL 240
Query: 239 ICGVGIFMHRRSKKVQRG 256
G G+F++ R++K G
Sbjct: 241 FLGAGLFIYFRNQKGHSG 258
>gi|239740857 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 3 isoform 2 [Homo sapiens]
Length = 266
Score = 313 bits (802), Expect = 9e-86
Identities = 154/258 (59%), Positives = 188/258 (72%), Gaps = 2/258 (0%)
Query: 1 MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQR--FLERYI 58
M+ L++ LT LMVL + + T +L EC+ FNGT+R +L+RY
Sbjct: 1 MVCLRLPGGSCMAVLTVTLMVLSSPLALAGDTRPRFLEYSTSECHFFNGTERVRYLDRYF 60
Query: 59 YNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTL 118
+N+EE RFDSDVGEFRAVTELGRP AEYWNSQKD+LE+KR D CRHNY + T+
Sbjct: 61 HNQEENVRFDSDVGEFRAVTELGRPDAEYWNSQKDLLEQKRGRVDNYCRHNYGVVESFTV 120
Query: 119 QRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNG 178
QRRV P+V V PSK PLQHHNLLVC V+ FYPGSI+VRWF NGQEE GVVST LI NG
Sbjct: 121 QRRVHPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNG 180
Query: 179 DWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLI 238
DWTFQ LVMLE P+ G+VYTCQVEH S+ SP+TVEW+A+S+SA+SK L+G GGFVLGL+
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL 240
Query: 239 ICGVGIFMHRRSKKVQRG 256
G G+F++ R++K G
Sbjct: 241 FLGAGLFIYFRNQKGHSG 258
>gi|18641375 major histocompatibility complex, class II, DR beta 5
precursor [Homo sapiens]
Length = 266
Score = 313 bits (802), Expect = 9e-86
Identities = 154/258 (59%), Positives = 190/258 (73%), Gaps = 2/258 (0%)
Query: 1 MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQR--FLERYI 58
M+ L++ LT LMVL + + T +L Q + EC+ FNGT+R FL R I
Sbjct: 1 MVCLKLPGGSYMAKLTVTLMVLSSPLALAGDTRPRFLQQDKYECHFFNGTERVRFLHRDI 60
Query: 59 YNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTL 118
YN+EE RFDSDVGE+RAVTELGRP AEYWNSQKD LE++RA D CRHNY +G T+
Sbjct: 61 YNQEEDLRFDSDVGEYRAVTELGRPDAEYWNSQKDFLEDRRAAVDTYCRHNYGVGESFTV 120
Query: 119 QRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNG 178
QRRV+P+V V P++ LQHHNLLVC V FYPGSI+VRWF N QEE AGVVST LI+NG
Sbjct: 121 QRRVEPKVTVYPARTQTLQHHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLIQNG 180
Query: 179 DWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLI 238
DWTFQ LVMLE P+ G+VYTCQVEH S+ SP+TVEW+AQS+SA+SK L+G GGFVLGL+
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRAQSESAQSKMLSGVGGFVLGLL 240
Query: 239 ICGVGIFMHRRSKKVQRG 256
G G+F++ +++K G
Sbjct: 241 FLGAGLFIYFKNQKGHSG 258
>gi|239740743 PREDICTED: similar to HLA class II histocompatibility
antigen, DRB1-7 beta chain isoform 2 [Homo sapiens]
Length = 264
Score = 313 bits (801), Expect = 1e-85
Identities = 148/223 (66%), Positives = 180/223 (80%), Gaps = 2/223 (0%)
Query: 36 YLFQGRQECYAFNGTQR--FLERYIYNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKD 93
+L+QG+ +C+ FNGT+R FLER YN+EEF RFDSDVGE+RAVTELGRP AE WNSQKD
Sbjct: 34 FLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQKD 93
Query: 94 ILEEKRAVPDRMCRHNYELGGPMTLQRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGS 153
ILE++R D +CRHNY +G T+QRRV P V V P+K PLQHHNLLVC V+ FYPGS
Sbjct: 94 ILEDRRGQVDTVCRHNYGVGESFTVQRRVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGS 153
Query: 154 IQVRWFLNGQEETAGVVSTNLIRNGDWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTV 213
I+VRWF NGQEE AGVVST LI+NGDWTFQ LVMLE P+ G+VYTCQVEH S+ SP+TV
Sbjct: 154 IEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTV 213
Query: 214 EWKAQSDSARSKTLTGAGGFVLGLIICGVGIFMHRRSKKVQRG 256
EW+A+S+SA+SK L+G GGFVLGL+ G G+F++ R++K G
Sbjct: 214 EWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSG 256
>gi|239740693 PREDICTED: similar to HLA class II histocompatibility
antigen, DRB1-7 beta chain isoform 2 [Homo sapiens]
Length = 264
Score = 313 bits (801), Expect = 1e-85
Identities = 148/223 (66%), Positives = 180/223 (80%), Gaps = 2/223 (0%)
Query: 36 YLFQGRQECYAFNGTQR--FLERYIYNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKD 93
+L+QG+ +C+ FNGT+R FLER YN+EEF RFDSDVGE+RAVTELGRP AE WNSQKD
Sbjct: 34 FLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQKD 93
Query: 94 ILEEKRAVPDRMCRHNYELGGPMTLQRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGS 153
ILE++R D +CRHNY +G T+QRRV P V V P+K PLQHHNLLVC V+ FYPGS
Sbjct: 94 ILEDRRGQVDTVCRHNYGVGESFTVQRRVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGS 153
Query: 154 IQVRWFLNGQEETAGVVSTNLIRNGDWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTV 213
I+VRWF NGQEE AGVVST LI+NGDWTFQ LVMLE P+ G+VYTCQVEH S+ SP+TV
Sbjct: 154 IEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTV 213
Query: 214 EWKAQSDSARSKTLTGAGGFVLGLIICGVGIFMHRRSKKVQRG 256
EW+A+S+SA+SK L+G GGFVLGL+ G G+F++ R++K G
Sbjct: 214 EWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSG 256
>gi|52630344 major histocompatibility complex, class II, DR beta 4
precursor [Homo sapiens]
Length = 266
Score = 308 bits (789), Expect = 3e-84
Identities = 152/258 (58%), Positives = 191/258 (74%), Gaps = 2/258 (0%)
Query: 1 MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQRF--LERYI 58
M+ L++ ALT L VL + + T +L Q + EC+ NGT+R L RYI
Sbjct: 1 MVCLKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYI 60
Query: 59 YNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTL 118
YN+EE+AR++SD+GE++AVTELGRP AEYWNSQKD+LE +RA D CR+NY + T+
Sbjct: 61 YNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTV 120
Query: 119 QRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNG 178
QRRVQP+V V PSK PLQHHNLLVC V FYPGSI+VRWF NGQEE AGVVST LI+NG
Sbjct: 121 QRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180
Query: 179 DWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLI 238
DWTFQ LVMLE P+ G+VYTCQVEH S+ SP+TV+W A+S+SA+SK L+G GGFVLGL+
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLL 240
Query: 239 ICGVGIFMHRRSKKVQRG 256
G G+F++ R++K G
Sbjct: 241 FLGTGLFIYFRNQKGHSG 258
>gi|239740859 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 3 isoform 1 [Homo sapiens]
Length = 267
Score = 308 bits (789), Expect = 3e-84
Identities = 154/259 (59%), Positives = 190/259 (73%), Gaps = 3/259 (1%)
Query: 1 MMVLQVSAAPRTVALTALLMVLLTSV-VQGRATPENYLFQGRQECYAFNGTQR--FLERY 57
M+ L++ LT LMVL + + + G + L+ EC+ FNGT+R +L+RY
Sbjct: 1 MVCLRLPGGSCMAVLTVTLMVLSSPLALAGDTRRKCTLWVPTSECHFFNGTERVRYLDRY 60
Query: 58 IYNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMT 117
+N+EE RFDSDVGEFRAVTELGRP AEYWNSQKD+LE+KR D CRHNY + T
Sbjct: 61 FHNQEENVRFDSDVGEFRAVTELGRPDAEYWNSQKDLLEQKRGRVDNYCRHNYGVVESFT 120
Query: 118 LQRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRN 177
+QRRV P+V V PSK PLQHHNLLVC V+ FYPGSI+VRWF NGQEE GVVST LI N
Sbjct: 121 VQRRVHPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHN 180
Query: 178 GDWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGL 237
GDWTFQ LVMLE P+ G+VYTCQVEH S+ SP+TVEW+A+S+SA+SK L+G GGFVLGL
Sbjct: 181 GDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGL 240
Query: 238 IICGVGIFMHRRSKKVQRG 256
+ G G+F++ R++K G
Sbjct: 241 LFLGAGLFIYFRNQKGHSG 259
>gi|239758090 PREDICTED: major histocompatibility complex, class II,
DR beta 4 [Homo sapiens]
Length = 278
Score = 300 bits (767), Expect = 1e-81
Identities = 144/229 (62%), Positives = 178/229 (77%), Gaps = 2/229 (0%)
Query: 30 RATPENYLFQGRQECYAFNGTQRF--LERYIYNREEFARFDSDVGEFRAVTELGRPAAEY 87
R +L Q + EC+ NGT+R L RYIYN+EE+AR++SD+GE++AVTELGRP AEY
Sbjct: 42 RVPTARFLEQAKCECHFLNGTERVWNLIRYIYNQEEYARYNSDLGEYQAVTELGRPDAEY 101
Query: 88 WNSQKDILEEKRAVPDRMCRHNYELGGPMTLQRRVQPRVNVSPSKKGPLQHHNLLVCHVT 147
WNSQKD+LE +RA D CR+NY + T+QRRVQP+V V PSK PLQHHNLLVC V
Sbjct: 102 WNSQKDLLERRRAEVDTYCRYNYGVVESFTVQRRVQPKVTVYPSKTQPLQHHNLLVCSVN 161
Query: 148 DFYPGSIQVRWFLNGQEETAGVVSTNLIRNGDWTFQILVMLEMTPQQGDVYTCQVEHTSL 207
FYPGSI+VRWF NGQEE AGVVST LI+NGDWTFQ LVMLE P+ G+VYTCQVEH S+
Sbjct: 162 GFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSM 221
Query: 208 DSPVTVEWKAQSDSARSKTLTGAGGFVLGLIICGVGIFMHRRSKKVQRG 256
SP+TV+W A+S+SA+SK L+G GGFVLGL+ G G+F++ R++K G
Sbjct: 222 MSPLTVQWSARSESAQSKMLSGVGGFVLGLLFLGTGLFIYFRNQKGHSG 270
>gi|239758092 PREDICTED: similar to HLA class II histocompatibility
antigen, DRB1-7 beta chain [Homo sapiens]
Length = 253
Score = 275 bits (703), Expect = 3e-74
Identities = 143/258 (55%), Positives = 178/258 (68%), Gaps = 15/258 (5%)
Query: 1 MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQR--FLERYI 58
M+ L++ ALT LMVL + + T +L+QG+ +C+ FNGT+R FLER
Sbjct: 1 MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60
Query: 59 YNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTL 118
YN+EEF RFDSDVGE+RAVTELGRP AE Q D+L +PD P+
Sbjct: 61 YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----CLPDSF---------PLPC 107
Query: 119 QRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNG 178
V P V V P+K PLQHHNLLVC V+ FYPGSI+VRWF NGQEE AGVVST LI+NG
Sbjct: 108 FLLVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 167
Query: 179 DWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLI 238
DWTFQ LVMLE P+ G+VYTCQVEH S+ SP+TVEW+A+S+SA+SK L+G GGFVLGL+
Sbjct: 168 DWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLL 227
Query: 239 ICGVGIFMHRRSKKVQRG 256
G G+F++ R++K G
Sbjct: 228 FLGAGLFIYFRNQKGHSG 245
>gi|4504403 major histocompatibility complex, class II, DO beta
precursor [Homo sapiens]
Length = 273
Score = 273 bits (699), Expect = 8e-74
Identities = 135/245 (55%), Positives = 175/245 (71%), Gaps = 2/245 (0%)
Query: 10 PRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQR--FLERYIYNREEFARF 67
P VAL L L +S+ QG +PE+++ Q + +CY NGT++ F+ R+I+N EE+ RF
Sbjct: 7 PWVVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRF 66
Query: 68 DSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTLQRRVQPRVN 127
DSDVG F A+T+LG+P AE WNS+ D+LE R D +CRHNY LG P T+ R+VQP V
Sbjct: 67 DSDVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVT 126
Query: 128 VSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNGDWTFQILVM 187
V P + L HNLL C VT FYPG I+++WFLNGQEE AGV+ST IRNGDWTFQ +VM
Sbjct: 127 VYPERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVM 186
Query: 188 LEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLIICGVGIFMH 247
LEMTP+ G VYTC V+H+SL SPV+VEW+AQS+ + K L+G F+LGLI VGI +
Sbjct: 187 LEMTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQ 246
Query: 248 RRSKK 252
R++K
Sbjct: 247 LRAQK 251
>gi|169217452 PREDICTED: similar to HLA class II histocompatibility
antigen, DRB1-4 beta chain, partial [Homo sapiens]
Length = 223
Score = 259 bits (662), Expect = 2e-69
Identities = 123/179 (68%), Positives = 141/179 (78%), Gaps = 2/179 (1%)
Query: 33 PENYLFQGRQECYAFNGTQR--FLERYIYNREEFARFDSDVGEFRAVTELGRPAAEYWNS 90
P +L Q + EC+ FNGT+R FL+RY Y++EE+ RFDSDVGE+RAVTELGRP AEYWNS
Sbjct: 45 PARFLEQVKHECHFFNGTERVRFLDRYFYHQEEYVRFDSDVGEYRAVTELGRPDAEYWNS 104
Query: 91 QKDILEEKRAVPDRMCRHNYELGGPMTLQRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFY 150
QKD+LE+KRA D CRHNY +G T+QRRV P V V P+K PLQHHNLLVC V FY
Sbjct: 105 QKDLLEQKRAAVDTYCRHNYGVGESFTVQRRVYPEVTVYPAKTQPLQHHNLLVCSVNGFY 164
Query: 151 PGSIQVRWFLNGQEETAGVVSTNLIRNGDWTFQILVMLEMTPQQGDVYTCQVEHTSLDS 209
PGSI+VRWF NGQEE GVVST LI+NGDWTFQ LVMLE P+ G+VYTCQVEH SL S
Sbjct: 165 PGSIEVRWFRNGQEEKTGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSLTS 223
>gi|169168671 PREDICTED: similar to MHC class II antigen [Homo
sapiens]
Length = 241
Score = 177 bits (448), Expect = 1e-44
Identities = 82/135 (60%), Positives = 104/135 (77%)
Query: 122 VQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNGDWT 181
+QP+ + P+K PL H N LVC V+ FYPGSI+VRWF NGQEE A VVS LI+NGDWT
Sbjct: 99 LQPKGTMYPAKTEPLHHRNPLVCSVSGFYPGSIEVRWFQNGQEEKAAVVSIGLIQNGDWT 158
Query: 182 FQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLIICG 241
FQ LVMLE P+ G+VYTCQVEH S+ SP+TVEW A+++SA+SK L+G GGFVLGL+ G
Sbjct: 159 FQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWSARTESAQSKMLSGVGGFVLGLLFLG 218
Query: 242 VGIFMHRRSKKVQRG 256
G+F++ R++K G
Sbjct: 219 TGLFIYFRNQKGHSG 233
>gi|169168589 PREDICTED: similar to MHC class II antigen [Homo
sapiens]
Length = 140
Score = 118 bits (295), Expect = 6e-27
Identities = 61/123 (49%), Positives = 82/123 (66%), Gaps = 2/123 (1%)
Query: 1 MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQRF--LERYI 58
M+ L++ ALT L VL + + T +L Q + EC+ NGT+R L RYI
Sbjct: 1 MVCLKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYI 60
Query: 59 YNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTL 118
YN+EE+AR++SD+GE++AVTELGRP AEYWNSQKD+LE +RA D CR+NY + T+
Sbjct: 61 YNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTV 120
Query: 119 QRR 121
QRR
Sbjct: 121 QRR 123
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.135 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,882,455
Number of Sequences: 37866
Number of extensions: 442788
Number of successful extensions: 1024
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 87
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 844
Number of HSP's gapped (non-prelim): 139
length of query: 258
length of database: 18,247,518
effective HSP length: 100
effective length of query: 158
effective length of database: 14,460,918
effective search space: 2284825044
effective search space used: 2284825044
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.