Search of human proteins with 24430192

Search of human proteins with 24430192

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24430192 keratin 16 [Homo sapiens]
         (473 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|24430192 keratin 16 [Homo sapiens]                                 919   0.0  
gi|15431310 keratin 14 [Homo sapiens]                                 768   0.0  
gi|4557701 keratin 17 [Homo sapiens]                                  580   e-165
gi|24430190 keratin 15 [Homo sapiens]                                 553   e-157
gi|131412225 keratin 13 isoform a [Homo sapiens]                      552   e-157
gi|131412228 keratin 13 isoform b [Homo sapiens]                      543   e-154
gi|195972866 keratin 10 [Homo sapiens]                                489   e-138
gi|24234699 keratin 19 [Homo sapiens]                                 486   e-137
gi|4557699 keratin 12 [Homo sapiens]                                  469   e-132
gi|192807292 keratin 24 [Homo sapiens]                                439   e-123
gi|55956899 keratin 9 [Homo sapiens]                                  432   e-121
gi|4504927 keratin 36 [Homo sapiens]                                  432   e-121
gi|153945736 keratin 27 [Homo sapiens]                                421   e-118
gi|31559829 keratin 25 [Homo sapiens]                                 409   e-114
gi|114431246 keratin 25D [Homo sapiens]                               408   e-114
gi|94538345 keratin 35 [Homo sapiens]                                 402   e-112
gi|31559815 keratin 26 [Homo sapiens]                                 386   e-107
gi|14917115 keratin 31 [Homo sapiens]                                 375   e-104
gi|14917117 keratin 33A [Homo sapiens]                                374   e-103
gi|10337581 type I hair keratin 3B [Homo sapiens]                     370   e-102
gi|27894337 keratin 20 [Homo sapiens]                                 367   e-101
gi|14917119 keratin 34 [Homo sapiens]                                 363   e-100
gi|116488398 keratin 32 [Homo sapiens]                                360   1e-99
gi|40354195 keratin 18 [Homo sapiens]                                 339   3e-93
gi|4557888 keratin 18 [Homo sapiens]                                  339   3e-93
gi|125490370 type I hair keratin KA36 [Homo sapiens]                  333   2e-91
gi|15431318 keratin 38 [Homo sapiens]                                 318   9e-87
gi|27894339 keratin 23 [Homo sapiens]                                 317   2e-86
gi|148277620 type I hair keratin KA35 [Homo sapiens]                  313   3e-85
gi|55770882 keratin 37 [Homo sapiens]                                 311   6e-85

>gi|24430192 keratin 16 [Homo sapiens]
          Length = 473

 Score =  919 bits (2374), Expect = 0.0
 Identities = 473/473 (100%), Positives = 473/473 (100%)

Query: 1   MTTCSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSGG 60
           MTTCSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSGG
Sbjct: 1   MTTCSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSGG 60

Query: 61  ACGLGGGYGGGFSSSSSFGSGFGGGYGGGLGAGFGGGLGAGFGGGFAGGDGLLVGSEKVT 120
           ACGLGGGYGGGFSSSSSFGSGFGGGYGGGLGAGFGGGLGAGFGGGFAGGDGLLVGSEKVT
Sbjct: 61  ACGLGGGYGGGFSSSSSFGSGFGGGYGGGLGAGFGGGLGAGFGGGFAGGDGLLVGSEKVT 120

Query: 121 MQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIKDYSPYFKTIEDLRNKIIA 180
           MQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIKDYSPYFKTIEDLRNKIIA
Sbjct: 121 MQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIKDYSPYFKTIEDLRNKIIA 180

Query: 181 ATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDELTLARTDLEMQ 240
           ATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDELTLARTDLEMQ
Sbjct: 181 ATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDELTLARTDLEMQ 240

Query: 241 IEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEKN 300
           IEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEKN
Sbjct: 241 IEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEKN 300

Query: 301 RRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQSQLSMKASLENS 360
           RRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQSQLSMKASLENS
Sbjct: 301 RRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQSQLSMKASLENS 360

Query: 361 LEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLEQEIATYRRL 420
           LEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLEQEIATYRRL
Sbjct: 361 LEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLEQEIATYRRL 420

Query: 421 LEGEDAHLSSQQASGQSYSSREVFTSSSSSSSRQTRPILKEQSSSSFSQGQSS 473
           LEGEDAHLSSQQASGQSYSSREVFTSSSSSSSRQTRPILKEQSSSSFSQGQSS
Sbjct: 421 LEGEDAHLSSQQASGQSYSSREVFTSSSSSSSRQTRPILKEQSSSSFSQGQSS 473


>gi|15431310 keratin 14 [Homo sapiens]
          Length = 472

 Score =  768 bits (1984), Expect = 0.0
 Identities = 400/458 (87%), Positives = 423/458 (92%), Gaps = 11/458 (2%)

Query: 1   MTTCSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSS-RFSSG 59
           MTTCSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSS RFSSG
Sbjct: 1   MTTCSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSSRFSSG 60

Query: 60  GACGLGGGYGGGFSSSSS-FGSGFGGGYGGGLGAGFGGGLGAGFGGGFAGGDGLLVGSEK 118
           GA GLGGGYGGGFSSSSS FGSGFGGGYGGGLGAG GGG    FGGGFAGGDGLLVGSEK
Sbjct: 61  GAYGLGGGYGGGFSSSSSSFGSGFGGGYGGGLGAGLGGG----FGGGFAGGDGLLVGSEK 116

Query: 119 VTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIKDYSPYFKTIEDLRNKI 178
           VTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRP+EIKDYSPYFKTIEDLRNKI
Sbjct: 117 VTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIKDYSPYFKTIEDLRNKI 176

Query: 179 IAATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDELTLARTDLE 238
           + AT++NA  +LQIDNARLAADDFRTKYE EL LR +VEAD+NGLRRVLDELTLAR DLE
Sbjct: 177 LTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARADLE 236

Query: 239 MQIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAE 298
           MQIE LKEELAYL+KNHEEEM ALRGQ GGDVNVEMDAAPGVDLSRILNEMRDQYE+MAE
Sbjct: 237 MQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMAE 296

Query: 299 KNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQSQLSMKASLE 358
           KNR+DAE WF +KTEELN+EVA+NSELVQS +SE++ELRR +Q LEIELQSQLSMKASLE
Sbjct: 297 KNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSMKASLE 356

Query: 359 NSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLEQEIATYR 418
           NSLEETKGRYCMQL+QIQ +IGSVEEQLAQLRCEMEQQ+QEY+ILLDVKTRLEQEIATYR
Sbjct: 357 NSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYR 416

Query: 419 RLLEGEDAHLSSQQASGQSYSSREVFTSSSSSSSRQTR 456
           RLLEGEDAHLSS Q S  S SSR+V     +SSSRQ R
Sbjct: 417 RLLEGEDAHLSSSQFSSGSQSSRDV-----TSSSRQIR 449


>gi|4557701 keratin 17 [Homo sapiens]
          Length = 432

 Score =  580 bits (1494), Expect = e-165
 Identities = 311/446 (69%), Positives = 350/446 (78%), Gaps = 37/446 (8%)

Query: 1   MTTCSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSGG 60
           MTT  RQFTSSSS+KGS G+GGG    S R+S  L  GSCR                 G 
Sbjct: 1   MTTSIRQFTSSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRL----------------GS 44

Query: 61  ACGLGGGYGGG-FSSSSSFGSGFGGGYGGGLGAGFGGGLGAGFGGGFAGGDGLLVGSEKV 119
           A GLG   GG  +SS  SFGSG                   G+G  F G DGLL G EK 
Sbjct: 45  AGGLGSTLGGSSYSSCYSFGSG------------------GGYGSSFGGVDGLLAGGEKA 86

Query: 120 TMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIKDYSPYFKTIEDLRNKII 179
           TMQNLNDRLASYLDKVRALEEAN +LEVKIRDWYQRQ P   +DYS Y++TIE+L+NKI+
Sbjct: 87  TMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQAPGPARDYSQYYRTIEELQNKIL 146

Query: 180 AATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDELTLARTDLEM 239
            AT++NA  +LQIDNARLAADDFRTK+E E ALR +VEAD+NGLRRVLDELTLAR DLEM
Sbjct: 147 TATVDNANILLQIDNARLAADDFRTKFETEQALRLSVEADINGLRRVLDELTLARADLEM 206

Query: 240 QIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK 299
           QIE LKEELAYL+KNHEEEM ALRGQ GG++NVEMDAAPGVDLSRILNEMRDQYE+MAEK
Sbjct: 207 QIENLKEELAYLKKNHEEEMNALRGQVGGEINVEMDAAPGVDLSRILNEMRDQYEKMAEK 266

Query: 300 NRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQSQLSMKASLEN 359
           NR+DAE WF SKTEELN+EVA+NSELVQS +SE++ELRR +Q LEIELQSQLSMKASLE 
Sbjct: 267 NRKDAEDWFFSKTEELNREVATNSELVQSGKSEISELRRTMQALEIELQSQLSMKASLEG 326

Query: 360 SLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLEQEIATYRR 419
           +L ET+ RYC+QLSQIQGLIGSVEEQLAQLRCEMEQQ+QEY+ILLDVKTRLEQEIATYRR
Sbjct: 327 NLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRR 386

Query: 420 LLEGEDAHLSSQQASGQSYSSREVFT 445
           LLEGEDAHL+  Q   +  ++R+V T
Sbjct: 387 LLEGEDAHLT--QYKKEPVTTRQVRT 410


>gi|24430190 keratin 15 [Homo sapiens]
          Length = 456

 Score =  553 bits (1424), Expect = e-157
 Identities = 298/437 (68%), Positives = 344/437 (78%), Gaps = 27/437 (6%)

Query: 1   MTTCSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGG-----LSVSS- 54
           MTT   Q +SS+            GGGS+R  S+LAGG      +  GG     +S SS 
Sbjct: 1   MTTTFLQTSSST-----------FGGGSTRGGSLLAGGGGFGGGSLSGGGGSRSISASSA 49

Query: 55  RFSSGGACGLGGGYGGGFSSSSSFGSGFGGGYGGGLGAGFGGGLGAGFGGGFAGGDG-LL 113
           RF S G+   GGGYGGG         GFGGG G   G GFGGG+G GFGGGF GGDG LL
Sbjct: 50  RFVSSGS---GGGYGGGMRVC-----GFGGGAGSVFGGGFGGGVGGGFGGGFGGGDGGLL 101

Query: 114 VGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIK-DYSPYFKTIE 172
            G+EK+TMQNLNDRLASYLDKVRALEEANADLEVKI DWYQ+Q P+  + DYS YFKTIE
Sbjct: 102 SGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPTSPECDYSQYFKTIE 161

Query: 173 DLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDELTL 232
           +LR+KI+A TI+N++ IL+IDNARLAADDFR KYE+ELALRQ VEAD+NGLRRVLDELTL
Sbjct: 162 ELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTL 221

Query: 233 ARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQ 292
           ARTDLEMQIEGL EELAYL+KNHEEEM     Q  G VNVEMDAAPGVDL+R+L EMR+Q
Sbjct: 222 ARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMREQ 281

Query: 293 YEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQSQLS 352
           YE MAEKNRRD E WF SKTEELNKEVASN+E++Q+S++E+T+LRR +Q LEIELQSQLS
Sbjct: 282 YEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQSQLS 341

Query: 353 MKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLEQ 412
           MKA LENSL ET+ RY  QL QIQGLIG +E QL++LRCEME Q+QEY++LLD+KTRLEQ
Sbjct: 342 MKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTRLEQ 401

Query: 413 EIATYRRLLEGEDAHLS 429
           EIATYR LLEG+DA ++
Sbjct: 402 EIATYRSLLEGQDAKMA 418


>gi|131412225 keratin 13 isoform a [Homo sapiens]
          Length = 458

 Score =  552 bits (1423), Expect = e-157
 Identities = 293/453 (64%), Positives = 351/453 (77%), Gaps = 32/453 (7%)

Query: 17  SCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSS---RFSSGGACGLGGGYGGGFS 73
           S   GGG GGGS ++               GGG  VS+   RF SGG+ G   GYGGG S
Sbjct: 9   SASYGGGFGGGSCQL---------------GGGRGVSTCSTRFVSGGSAG---GYGGGVS 50

Query: 74  SS--SSFGSGFGGGYGGGLGAGFGGGLGAGFGGGFAGG--------DGLLVGSEKVTMQN 123
                  GSGFGGGYGGGLG G+GGGLG GFGGGFAGG         GLL G+EK+TMQN
Sbjct: 51  CGFGGGAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQN 110

Query: 124 LNDRLASYLDKVRALEEANADLEVKIRDWYQRQRP-SEIKDYSPYFKTIEDLRNKIIAAT 182
           LNDRLASYL+KVRALEEANADLEVKIRDW+ +Q P S  +DYSPY+KTIE+LR+KI+ AT
Sbjct: 111 LNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTAT 170

Query: 183 IENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDELTLARTDLEMQIE 242
           IEN + IL+IDNARLAADDFR KYE+ELALRQ+VEAD+NGLRRVLDELTL++TDLEMQIE
Sbjct: 171 IENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIE 230

Query: 243 GLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEKNRR 302
            L EELAY++KNHEEEM     Q  G VNVEMDA PG+DL+R+L EMR+QYE MAE+NRR
Sbjct: 231 SLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRR 290

Query: 303 DAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQSQLSMKASLENSLE 362
           DAE WF +K+ ELNKEV++N+ ++Q+S++E+TELRR LQGLEIELQSQLSMKA LEN++ 
Sbjct: 291 DAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVA 350

Query: 363 ETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLEQEIATYRRLLE 422
           ET+ RY +QL QIQGLI S+E QL++LR EME Q+QEY++LLD+KTRLEQEIATYR LLE
Sbjct: 351 ETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLE 410

Query: 423 GEDAHLSSQQASGQSYSSREVFTSSSSSSSRQT 455
           G+DA +    +S  S S R    +++SS+S  T
Sbjct: 411 GQDAKMIGFPSSAGSVSPRSTSVTTTSSASVTT 443


>gi|131412228 keratin 13 isoform b [Homo sapiens]
          Length = 420

 Score =  543 bits (1399), Expect = e-154
 Identities = 285/424 (67%), Positives = 337/424 (79%), Gaps = 32/424 (7%)

Query: 17  SCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSS---RFSSGGACGLGGGYGGGFS 73
           S   GGG GGGS ++               GGG  VS+   RF SGG+ G   GYGGG S
Sbjct: 9   SASYGGGFGGGSCQL---------------GGGRGVSTCSTRFVSGGSAG---GYGGGVS 50

Query: 74  SS--SSFGSGFGGGYGGGLGAGFGGGLGAGFGGGFAGG--------DGLLVGSEKVTMQN 123
                  GSGFGGGYGGGLG G+GGGLG GFGGGFAGG         GLL G+EK+TMQN
Sbjct: 51  CGFGGGAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQN 110

Query: 124 LNDRLASYLDKVRALEEANADLEVKIRDWYQRQRP-SEIKDYSPYFKTIEDLRNKIIAAT 182
           LNDRLASYL+KVRALEEANADLEVKIRDW+ +Q P S  +DYSPY+KTIE+LR+KI+ AT
Sbjct: 111 LNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTAT 170

Query: 183 IENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDELTLARTDLEMQIE 242
           IEN + IL+IDNARLAADDFR KYE+ELALRQ+VEAD+NGLRRVLDELTL++TDLEMQIE
Sbjct: 171 IENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIE 230

Query: 243 GLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEKNRR 302
            L EELAY++KNHEEEM     Q  G VNVEMDA PG+DL+R+L EMR+QYE MAE+NRR
Sbjct: 231 SLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRR 290

Query: 303 DAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQSQLSMKASLENSLE 362
           DAE WF +K+ ELNKEV++N+ ++Q+S++E+TELRR LQGLEIELQSQLSMKA LEN++ 
Sbjct: 291 DAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVA 350

Query: 363 ETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLEQEIATYRRLLE 422
           ET+ RY +QL QIQGLI S+E QL++LR EME Q+QEY++LLD+KTRLEQEIATYR LLE
Sbjct: 351 ETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLE 410

Query: 423 GEDA 426
           G+DA
Sbjct: 411 GQDA 414


>gi|195972866 keratin 10 [Homo sapiens]
          Length = 584

 Score =  489 bits (1259), Expect = e-138
 Identities = 268/424 (63%), Positives = 316/424 (74%), Gaps = 15/424 (3%)

Query: 12  SSMKGSCGIG---GGIGGGS-SRISSVLAGGSCRAPSTYG----GGLSVSSRFSSGGACG 63
           SS KGS G G   GG  GGS SR SS   GG C   S+ G    GG    S   S G+  
Sbjct: 37  SSSKGSLGGGFSSGGFSGGSFSRGSS---GGGCFGGSSGGYGGLGGFGGGSFRGSYGSSS 93

Query: 64  LGGGYGGGFSSSSSFGSGFGGGYGGGLGAGFGGGLGAGFGGGFAGGDGLLVGSEKVTMQN 123
            GG YGG F   S  G  FGGG  GG G G GGG G GFGGGF G  GLL G+EKVTMQN
Sbjct: 94  FGGSYGGSFGGGSFGGGSFGGGSFGGGGFG-GGGFGGGFGGGFGGDGGLLSGNEKVTMQN 152

Query: 124 LNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPS---EIKDYSPYFKTIEDLRNKIIA 180
           LNDRLASYLDKVRALEE+N +LE KI++WY++   S   E +DYS Y+KTI+DL+N+I+ 
Sbjct: 153 LNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSHQGEPRDYSKYYKTIDDLKNQILN 212

Query: 181 ATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDELTLARTDLEMQ 240
            T +NA  +LQIDNARLAADDFR KYE+E+ALRQ+VEAD+NGLRRVLDELTL + DLEMQ
Sbjct: 213 LTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEADINGLRRVLDELTLTKADLEMQ 272

Query: 241 IEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEKN 300
           IE L EELAYL+KNHEEEM  LR  + GDVNVEM+AAPGVDL+++LN MR QYEQ+AE+N
Sbjct: 273 IESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQN 332

Query: 301 RRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQSQLSMKASLENS 360
           R+DAE WF  K++EL  E+ +N E + S +SE+TELRR +Q LEIELQSQL++K SLE S
Sbjct: 333 RKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELRRNVQALEIELQSQLALKQSLEAS 392

Query: 361 LEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLEQEIATYRRL 420
           L ET+GRYC+QLSQIQ  I ++EEQL Q+R E E Q+ EYQ LLD+K RLE EI TYR L
Sbjct: 393 LAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNTEYQQLLDIKIRLENEIQTYRSL 452

Query: 421 LEGE 424
           LEGE
Sbjct: 453 LEGE 456



 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 44/101 (43%), Positives = 51/101 (50%), Gaps = 9/101 (8%)

Query: 9   TSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSGGACGLGGGY 68
           +S    +G    GGG GGGSS       GGS  +   +GGG   SS    GG    GG  
Sbjct: 458 SSGGGGRGGGSFGGGYGGGSS------GGGS--SGGGHGGGHGGSSGGGYGGGSSGGGSS 509

Query: 69  GGGFSSSSSFGSGFGGGYGGGLGAGFGGGLGAGFGGGFAGG 109
           GGG+   SS G G GG   GG G G  GG G G+GGG +GG
Sbjct: 510 GGGYGGGSSSG-GHGGSSSGGYGGGSSGGGGGGYGGGSSGG 549



 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 44/98 (44%), Positives = 49/98 (50%), Gaps = 15/98 (15%)

Query: 15  KGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSGGACGLGGGYGGGFSS 74
           +GS G GGG GGGS        GG       YGGG S       G   G GG  GGG+  
Sbjct: 456 EGSSG-GGGRGGGS------FGGG-------YGGGSSGGGSSGGGHGGGHGGSSGGGYGG 501

Query: 75  SSSFGSGFGGGYGGGLGA-GFGGGLGAGFGGGFAGGDG 111
            SS G   GGGYGGG  + G GG    G+GGG +GG G
Sbjct: 502 GSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGG 539



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 44/97 (45%), Positives = 49/97 (50%), Gaps = 14/97 (14%)

Query: 19  GIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSGGACGLGGGYGGGFSSSSSF 78
           G GGG  GG S       G    +   YGGG       SSGG    GGGYGGG SS    
Sbjct: 472 GYGGGSSGGGSSGGGHGGGHGGSSGGGYGGG-------SSGGGSS-GGGYGGGSSSGGHG 523

Query: 79  GS---GFGGGYGGGLGAGFGGGL---GAGFGGGFAGG 109
           GS   G+GGG  GG G G+GGG    G+  GGG+ GG
Sbjct: 524 GSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGG 560



 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 30/60 (50%), Positives = 34/60 (56%)

Query: 57  SSGGACGLGGGYGGGFSSSSSFGSGFGGGYGGGLGAGFGGGLGAGFGGGFAGGDGLLVGS 116
           SSGG    GG +GGG+   SS G   GGG+GGG G   GGG G G  GG + G G   GS
Sbjct: 458 SSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGS 517



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 41/91 (45%), Positives = 44/91 (48%), Gaps = 6/91 (6%)

Query: 16  GSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSGGACGLG-GGYGGGFSS 74
           G    GGG GGG    S    GG      + GGG    S  SSGG  G   GGYGGG  S
Sbjct: 479 GGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGS--SSGGHGGSSSGGYGGG--S 534

Query: 75  SSSFGSGFGGGYGGGLGAGFGGGLGAGFGGG 105
           S   G G+GGG  GG G+  GGG G G   G
Sbjct: 535 SGGGGGGYGGGSSGG-GSSSGGGYGGGSSSG 564



 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 37/84 (44%), Positives = 41/84 (48%), Gaps = 13/84 (15%)

Query: 10  SSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSGGACGLGGGYG 69
           SS    G    GGG  GG         GGS    S+ G G S S  +  G + G GGGYG
Sbjct: 494 SSGGGYGGGSSGGGSSGGG------YGGGS----SSGGHGGSSSGGYGGGSSGGGGGGYG 543

Query: 70  GGFSSSSSFGSGFGGGYGGGLGAG 93
           GG   SS  GS  GGGYGGG  +G
Sbjct: 544 GG---SSGGGSSSGGGYGGGSSSG 564



 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 38/88 (43%), Positives = 45/88 (51%), Gaps = 5/88 (5%)

Query: 21  GGGIGGGSSRISSVLAGGSCRAPSTYGG-GLSVSSRFSSGGACGLGGGYGGGFSSS-SSF 78
           GGG GGGSS   S  +GG     S+ GG G S S  +  G + G GGGYGGG S   SS 
Sbjct: 496 GGGYGGGSSGGGS--SGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSS 553

Query: 79  GSGFGG-GYGGGLGAGFGGGLGAGFGGG 105
           G G+GG    GG  +   G +G     G
Sbjct: 554 GGGYGGGSSSGGHKSSSSGSVGESSSKG 581



 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 35/76 (46%), Positives = 35/76 (46%), Gaps = 18/76 (23%)

Query: 16  GSCGIGGGIGGGSSR------ISSVLAGGSCRAPST-YGGGLSVSSRFSSGGACGLGGGY 68
           G    GGG GGGSS        S    GGS       YGGG       SSGG    GGGY
Sbjct: 505 GGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGG-------SSGGGSSSGGGY 557

Query: 69  GGGFSS----SSSFGS 80
           GGG SS    SSS GS
Sbjct: 558 GGGSSSGGHKSSSSGS 573


>gi|24234699 keratin 19 [Homo sapiens]
          Length = 400

 Score =  486 bits (1251), Expect = e-137
 Identities = 263/435 (60%), Positives = 322/435 (74%), Gaps = 39/435 (8%)

Query: 1   MTTCS-RQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSG 59
           MT+ S RQ +++SS        GG+GGGS R      G + RAPS +GG           
Sbjct: 1   MTSYSYRQSSATSSF-------GGLGGGSVRFGP---GVAFRAPSIHGGS---------- 40

Query: 60  GACGLGGGYGGGFSSSSSFGSGFGGGYGGGLGAGFGGGLGAGFGGGFAGGDGLLVGSEKV 119
                 GG G   SS+    S   G YGGG            +GG     DGLL G+EK+
Sbjct: 41  ------GGRGVSVSSARFVSSSSSGAYGGG------------YGGVLTASDGLLAGNEKL 82

Query: 120 TMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIKDYSPYFKTIEDLRNKII 179
           TMQNLNDRLASYLDKVRALE AN +LEVKIRDWYQ+Q P   +DYS Y+ TI+DLR+KI+
Sbjct: 83  TMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPGPSRDYSHYYTTIQDLRDKIL 142

Query: 180 AATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDELTLARTDLEM 239
            ATIEN++ +LQIDNARLAADDFRTK+E E ALR +VEAD+NGLRRVLDELTLARTDLEM
Sbjct: 143 GATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTLARTDLEM 202

Query: 240 QIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK 299
           QIEGLKEELAYL+KNHEEE+  LRGQ GG V+VE+D+APG DL++IL++MR QYE MAE+
Sbjct: 203 QIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQ 262

Query: 300 NRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQSQLSMKASLEN 359
           NR+DAE WF S+TEELN+EVA ++E +Q SRSEVT+LRR LQGLEIELQSQLSMKA+LE+
Sbjct: 263 NRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQSQLSMKAALED 322

Query: 360 SLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLEQEIATYRR 419
           +L ET+ R+  QL+ IQ LI  +E QL  +R + E+Q+QEYQ L+D+K+RLEQEIATYR 
Sbjct: 323 TLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSRLEQEIATYRS 382

Query: 420 LLEGEDAHLSSQQAS 434
           LLEG++ H ++  AS
Sbjct: 383 LLEGQEDHYNNLSAS 397


>gi|4557699 keratin 12 [Homo sapiens]
          Length = 494

 Score =  469 bits (1206), Expect = e-132
 Identities = 257/445 (57%), Positives = 317/445 (71%), Gaps = 15/445 (3%)

Query: 27  GSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSGGACGLGGGYGGGFSSSSSFGSGFGGGY 86
           G  R  S  + GS    S +G G S    FS+    G   G+GGG  S SS   G G GY
Sbjct: 28  GRPRGMSASSVGSGYGGSAFGFGASCGGGFSAASMFGSSSGFGGG--SGSSMAGGLGAGY 85

Query: 87  GGGLGAGFGGGLGAGFGGGFAGGD---------GLLVGSEKVTMQNLNDRLASYLDKVRA 137
           G  LG G  GGLG GFGG   GG          GLL GSEK TMQNLNDRLASYLDKVRA
Sbjct: 86  GRALGGGSFGGLGMGFGGSPGGGSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKVRA 145

Query: 138 LEEANADLEVKIRDWYQRQ----RPSEIKDYSPYFKTIEDLRNKIIAATIENAQPILQID 193
           LEEAN +LE KIR+WY+ +      +   DYS Y+  IEDLRNKII+A+I NAQ +LQID
Sbjct: 146 LEEANTELENKIREWYETRGTGTADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQID 205

Query: 194 NARLAADDFRTKYEHELALRQTVEADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLRK 253
           NARLAA+DFR KYE+ELALRQ VEAD+NGLRRVLDELTL RTDLEMQIE L EELAY++K
Sbjct: 206 NARLAAEDFRMKYENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKK 265

Query: 254 NHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEKNRRDAETWFLSKTE 313
           NHE+E+ + R    G+V+VEMDAAPGVDL+R+LN+MR QYE +AE+NR+DAE WF+ K+ 
Sbjct: 266 NHEDELQSFRVGGPGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSG 325

Query: 314 ELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQSQLSMKASLENSLEETKGRYCMQLS 373
           EL KE+++N+E +QSS+SEVT+LRR  Q LEIELQSQL+MK SLE+SL E +G YC QLS
Sbjct: 326 ELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLS 385

Query: 374 QIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLEQEIATYRRLLEGEDAHLSSQQA 433
           Q+Q LI ++E QL Q+R + E+Q+ ++Q LL+VK RLE EI TYRRLL+GE      +++
Sbjct: 386 QVQQLISNLEAQLLQVRADAERQNVDHQRLLNVKARLELEIETYRRLLDGEAQGDGLEES 445

Query: 434 SGQSYSSREVFTSSSSSSSRQTRPI 458
              + S  +  ++ SS    +TR I
Sbjct: 446 LFVTDSKSQAQSTDSSKDPTKTRKI 470


>gi|192807292 keratin 24 [Homo sapiens]
          Length = 525

 Score =  439 bits (1130), Expect = e-123
 Identities = 249/472 (52%), Positives = 322/472 (68%), Gaps = 40/472 (8%)

Query: 10  SSSSMKGSCGIGG----GIGGGSSRISSVLAGGSCRA-PSTYGGGLSVSSRFSSGGACGL 64
           SS S    CG+GG    G  GG+S  S  L+GGS  A   ++GGG          G+C +
Sbjct: 25  SSFSSGSRCGLGGSSAQGFRGGASSCS--LSGGSSGAFGGSFGGGF---------GSCSV 73

Query: 65  GGGYGGGFSSSSSFGSG--FGGGYGGGLGAGFGG------GLGAGF---GGGFAGG---D 110
           GGG+GG   S + FG G  FGG  G G G+GF G      G   GF   GGG  GG    
Sbjct: 74  GGGFGGASGSGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFYSYGGGMGGGVGDG 133

Query: 111 GLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEI-----KDYS 165
           GL  G EK TMQNLNDRLA+YLDKVRALEEAN DLE KI++WY +  P        +DYS
Sbjct: 134 GLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDGGSGRDYS 193

Query: 166 PYFKTIEDLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRR 225
            Y+  IEDLRN+IIAAT+ENA  IL IDNARLAADDFR KYE+EL LRQ+VEAD+NGLR+
Sbjct: 194 KYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEADINGLRK 253

Query: 226 VLDELTLARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRI 285
           VLD+LT+ R+DLEMQIE   EELAYLRKNHEEEM  ++G +GG+V VEM+AAPG DL+++
Sbjct: 254 VLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNAAPGTDLTKL 313

Query: 286 LNEMRDQYEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEI 345
           LN+MR QYE++AE+NRR+AE  F  ++  L  ++++++    S+++E+TEL+R LQ LEI
Sbjct: 314 LNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITELKRTLQALEI 373

Query: 346 ELQSQLSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLD 405
           ELQSQL+MK+SLE +L +T+  Y  QLS+IQ  I ++EE++ Q+  E + Q+ EY+ LLD
Sbjct: 374 ELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNAEYKQLLD 433

Query: 406 VKTRLEQEIATYRRLLEGED-----AHLSSQQASGQSYSSREVFTSSSSSSS 452
           +KTRLE EI TYRRLL+GE      A    + +   +  SR++ +  S S S
Sbjct: 434 IKTRLEVEIETYRRLLDGEGGGSSFAEFGGRNSGSVNMGSRDLVSGDSRSGS 485


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score =  432 bits (1112), Expect = e-121
 Identities = 238/442 (53%), Positives = 299/442 (67%), Gaps = 14/442 (3%)

Query: 6   RQFTSSSSMKGSCGIGG------GIGGGSSRISSVLAGGSCRAP--STYGGGLSVSSRFS 57
           R   S  S  G  G GG      G GGGSSR+     GGS         GGG S SS   
Sbjct: 29  RSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGGGFSASSLGG 88

Query: 58  S--GGACGLGGGYGGGFSSSSSFGSGFGGGYGGGLGAGFGGGLGA--GFGGGFAGGDG-L 112
              GG+ G GG  GGG+SSS  FG GFGGG GGG G G+G G G   GFGGG  GGDG +
Sbjct: 89  GFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGGI 148

Query: 113 LVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEI-KDYSPYFKTI 171
           L  +EK TMQ LN RLASYLDKV+ALEEAN DLE KI+DWY ++ P+ I K+YSPY+ TI
Sbjct: 149 LTANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQKNYSPYYNTI 208

Query: 172 EDLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDELT 231
           +DL+++I+  T+ N + +L IDN R+  DDFR K+E E  LRQ V+AD+NGLR+VLD LT
Sbjct: 209 DDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDNLT 268

Query: 232 LARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRD 291
           + ++DLEMQ E L+EEL  L+KNH+EEM  L GQ  GDVNVE++ APG DL++ LN+MR 
Sbjct: 269 MEKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDMRQ 328

Query: 292 QYEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQSQL 351
           +YEQ+  KNR+D E  + ++  ++  EV+S+ + VQSS  EVT+LR  +Q LEIELQSQL
Sbjct: 329 EYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQL 388

Query: 352 SMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLE 411
           S KA+LE SLE+TK RYC QL  IQ  I ++E Q+  +R E+E Q+QEY +LL +K RLE
Sbjct: 389 SKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMRLE 448

Query: 412 QEIATYRRLLEGEDAHLSSQQA 433
           +EI TY  LLEG      S  A
Sbjct: 449 KEIETYHNLLEGGQEDFESSGA 470



 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 49/110 (44%), Positives = 53/110 (48%), Gaps = 7/110 (6%)

Query: 8   FTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFS-SGGACGLGG 66
           F SS + K   G  GG GG   R S   +GGS      YGGG S       SG   G GG
Sbjct: 465 FESSGAGKIGLGGRGGSGGSYGRGSRGGSGGS------YGGGGSGGGYGGGSGSRGGSGG 518

Query: 67  GYGGGFSSSSSFGSGFGGGYGGGLGAGFGGGLGAGFGGGFAGGDGLLVGS 116
            YGGG  S    G G+GGG GGG   G GGG   G GG + GG G   GS
Sbjct: 519 SYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGS 568



 Score = 73.9 bits (180), Expect = 3e-13
 Identities = 49/108 (45%), Positives = 54/108 (50%), Gaps = 20/108 (18%)

Query: 11  SSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSGGACGLGGGYGG 70
           S    G  G GGG GGGS       +GGS      YGGG        SG   G GGGYGG
Sbjct: 493 SGGSYGGGGSGGGYGGGSGSRGG--SGGS------YGGG--------SGSGGGSGGGYGG 536

Query: 71  GFSSSSSFGSGFGGGYGGGLGAGFGGGLGA--GFGGGFAGGDGLLVGS 116
           G     S GS  GGG+ GG G  +GGG G+  G GGG+ GG G   GS
Sbjct: 537 GSGGGHSGGS--GGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGS 582



 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 48/110 (43%), Positives = 53/110 (48%), Gaps = 15/110 (13%)

Query: 10  SSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPS-TYGGGLSVSSRFSSGGACGLGGGY 68
           S  S  G  G GGG GGG         GGS    S   GGG S  S  + GG  G GGG 
Sbjct: 516 SGGSYGGGSGSGGGSGGG-------YGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGS 568

Query: 69  GGGFSSSSSFGSGFGGGYGGGLGAG------FGGGLGA-GFGGGFAGGDG 111
           GGG+   S    G GG +GGG G G      +GGG  A G GGG+ GG G
Sbjct: 569 GGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSG 618



 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 37/92 (40%), Positives = 46/92 (50%), Gaps = 13/92 (14%)

Query: 33  SVLAGGSCRAPSTYGGGLSVSSRFSSGGACGL-----------GGGYGGGFSSSSSFGSG 81
           ++L GG     S+  G + +  R  SGG+ G            GGG GGG+   S    G
Sbjct: 456 NLLEGGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGG 515

Query: 82  FGGGYGGGLGA--GFGGGLGAGFGGGFAGGDG 111
            GG YGGG G+  G GGG G G GGG +GG G
Sbjct: 516 SGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSG 547



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 29/61 (47%), Positives = 31/61 (50%), Gaps = 9/61 (14%)

Query: 19  GIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSGG---ACGLGGGYGGGFSSS 75
           G GGG GGGS       +GGS    S +GG     S  S GG   A G GGGYGGG   S
Sbjct: 567 GSGGGYGGGSGSRGG--SGGSHGGGSGFGG----ESGGSYGGGEEASGSGGGYGGGSGKS 620

Query: 76  S 76
           S
Sbjct: 621 S 621


>gi|4504927 keratin 36 [Homo sapiens]
          Length = 467

 Score =  432 bits (1112), Expect = e-121
 Identities = 239/429 (55%), Positives = 299/429 (69%), Gaps = 26/429 (6%)

Query: 3   TCSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSGGAC 62
           TC+  F S+ S+KG CG  GGI    SR+SS+ + GSCR PS  G    +SS  S  G  
Sbjct: 5   TCTPTF-STGSIKGLCGTAGGI----SRVSSIRSVGSCRVPSLAGAAGYISSARS--GLS 57

Query: 63  GLGGGYGGGFSSSSSFGSGFGGGYGGGLGAGFGGGLGAGFGGGFAGGDGLLVGSEKVTMQ 122
           GLG    G + SS    SGF                  G GG F   +G   GSEK TMQ
Sbjct: 58  GLGSCLPGSYLSSECHTSGF-----------------VGSGGWFC--EGSFNGSEKETMQ 98

Query: 123 NLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIKDYSPYFKTIEDLRNKIIAAT 182
            LNDRLA+YL+KVR LE  NA+LE +I++WY+ Q P    DY  YFKTIED + KI+   
Sbjct: 99  FLNDRLANYLEKVRQLERENAELESRIQEWYEFQIPYICPDYQSYFKTIEDFQQKILLTK 158

Query: 183 IENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDELTLARTDLEMQIE 242
            ENA+ +LQIDNA+LAADDFRTKYE EL+LRQ VEAD+NGLRR+LDELTL + DLE Q+E
Sbjct: 159 SENARLVLQIDNAKLAADDFRTKYETELSLRQLVEADINGLRRILDELTLCKADLEAQVE 218

Query: 243 GLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEKNRR 302
            LKEEL  L+KNHEEE+  LR Q G  +NVE+DAAP VDL++IL +MR QYE + E NRR
Sbjct: 219 SLKEELMCLKKNHEEEVSVLRCQLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENNRR 278

Query: 303 DAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQSQLSMKASLENSLE 362
           D E WF ++TEELN++V S+SE +Q  ++E+ ELRR +  LEIELQ+Q SM+ SLE++L 
Sbjct: 279 DVEAWFNTQTEELNQQVVSSSEQLQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLA 338

Query: 363 ETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLEQEIATYRRLLE 422
           ET+ RY  QL+Q+Q LI +VE QL+++RC++E+Q+QEYQ+LLDVK RLE EIATYR LLE
Sbjct: 339 ETEARYSSQLAQMQCLISNVEAQLSEIRCDLERQNQEYQVLLDVKARLEGEIATYRHLLE 398

Query: 423 GEDAHLSSQ 431
           GED  L  Q
Sbjct: 399 GEDCKLPPQ 407


>gi|153945736 keratin 27 [Homo sapiens]
          Length = 459

 Score =  421 bits (1082), Expect = e-118
 Identities = 238/436 (54%), Positives = 298/436 (68%), Gaps = 36/436 (8%)

Query: 5   SRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSGGACGL 64
           S +F+S+S   GSCG     G GS R+SS  AG                  F +G  CG+
Sbjct: 2   SVRFSSTSRRLGSCG-----GTGSVRLSSGGAG------------------FGAGNTCGV 38

Query: 65  GGGYGGGFSSSSSFGSGFGGGYGGGLGAGFGGGLGAGFGGGFAGGD-GLLVGSEKVTMQN 123
            G  G GFS +   GS   GGYGGGLG G      +     F G + GLL G+EKVTMQN
Sbjct: 39  PG-IGSGFSCAFG-GSSSAGGYGGGLGGG------SASCAAFTGNEHGLLSGNEKVTMQN 90

Query: 124 LNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIK----DYSPYFKTIEDLRNKII 179
           LNDRLASYL+ VRALEEANADLE KI+ WY++  P   +    DYS YF  I++L+N+II
Sbjct: 91  LNDRLASYLENVRALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPIIDELKNQII 150

Query: 180 AATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDELTLARTDLEM 239
           +AT  NA  +LQ DNARL ADDFR K+E+ELAL Q+VEAD+NGLRRVLDELTL RTDLE+
Sbjct: 151 SATTSNAHVVLQNDNARLTADDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEI 210

Query: 240 QIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK 299
           Q+E L EELAYL+KNHEEEM AL+   GG+VNVEM+AAPGVDL+ +LN MR +YE +AE+
Sbjct: 211 QLETLSEELAYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQ 270

Query: 300 NRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQSQLSMKASLEN 359
           NRRDAE WF  K+  L ++++ ++    S+R+E+ E++R LQ LEIELQS L+ K SLE 
Sbjct: 271 NRRDAEAWFNEKSASLQQQISDDAGATTSARNELIEMKRTLQTLEIELQSLLATKHSLEC 330

Query: 360 SLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLEQEIATYRR 419
           SL ET+  YC QL+QIQ  IG++EEQL Q+R E E Q  EY+ LLD+K  LE+EI TY  
Sbjct: 331 SLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKVHLEKEIETYCL 390

Query: 420 LLEGEDAHLSSQQASG 435
           L++GED   S  +  G
Sbjct: 391 LIDGEDGSCSKSKGYG 406


>gi|31559829 keratin 25 [Homo sapiens]
          Length = 450

 Score =  409 bits (1052), Expect = e-114
 Identities = 230/425 (54%), Positives = 285/425 (67%), Gaps = 26/425 (6%)

Query: 28  SSRISSVLAGGSCRAPST-----YGGGLSVSSRFSSGGACGLGGGYGGGFSSSSSFGSGF 82
           S R+SS  +  SC  P+T     YGGG S    F +G +CG+ G            GSGF
Sbjct: 2   SLRLSSA-SRRSCPRPTTGSLRLYGGGTS----FGTGNSCGISG-----------IGSGF 45

Query: 83  GGGYGGGLGAGFGGGLGAGFGGGFAGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEAN 142
              +GG    G  GG G    G      GLL G+EKVTMQNLNDRLASYLD V ALEEAN
Sbjct: 46  SSAFGGSSSGGNTGG-GNPCAGFTVNERGLLSGNEKVTMQNLNDRLASYLDSVHALEEAN 104

Query: 143 ADLEVKIRDWYQRQRPSEIK----DYSPYFKTIEDLRNKIIAATIENAQPILQIDNARLA 198
           ADLE KI+ WY++  P   +    DYS YF  I+DL+N+IIA+T  NA  +LQIDNARL 
Sbjct: 105 ADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPIIDDLKNQIIASTTSNANAVLQIDNARLT 164

Query: 199 ADDFRTKYEHELALRQTVEADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLRKNHEEE 258
           ADDFR KYE+ELAL Q+VEADVNGLRRVLDE+TL RTDLE+Q E L EE+ YL+KNH+EE
Sbjct: 165 ADDFRLKYENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEEMTYLKKNHKEE 224

Query: 259 MLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEKNRRDAETWFLSKTEELNKE 318
           M  L+   GG+VNVEM+AAPGVDL+ +LN MR +YE +AE+NRRDAE WF  K+  L ++
Sbjct: 225 MQVLQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQ 284

Query: 319 VASNSELVQSSRSEVTELRRVLQGLEIELQSQLSMKASLENSLEETKGRYCMQLSQIQGL 378
           ++ +     S+R+E+TE++R LQ LEIELQS L+ K SLE SL ET+  YC QL+QIQ  
Sbjct: 285 ISEDVGATTSARNELTEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQ 344

Query: 379 IGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLEQEIATYRRLLEGEDAHLSSQQASGQSY 438
           IG++EEQL Q+R E E Q  EY+ LLD+K  LE+EI TY  L+ G+D    S     + Y
Sbjct: 345 IGALEEQLHQVRTETEGQKLEYEQLLDIKLHLEKEIETYCLLIGGDDGACKSGGYKSKDY 404

Query: 439 SSREV 443
            S  V
Sbjct: 405 GSGNV 409


>gi|114431246 keratin 25D [Homo sapiens]
          Length = 464

 Score =  408 bits (1049), Expect = e-114
 Identities = 224/389 (57%), Positives = 274/389 (70%), Gaps = 6/389 (1%)

Query: 53  SSRFSSGGACGLGGGYGGGFSSSSSFGSGFGGGYGGGLGAGFGGG-LGAGFGGGFAGGDG 111
           S R  +GGA   G    GG  + S F    GGG G   G    GG LG     GFAG +G
Sbjct: 20  SVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFAGSEG 79

Query: 112 -LLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIK----DYSP 166
            LL G+EKVTMQNLNDRLASYLD VRALEEANA+LE KI+ WY++  P   +    DYS 
Sbjct: 80  GLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDHDYSR 139

Query: 167 YFKTIEDLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRV 226
           Y  TIEDL+NKII++T  NA  ILQIDNARLAADDFR KYE+EL L Q VEAD+NGLRRV
Sbjct: 140 YHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGLRRV 199

Query: 227 LDELTLARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRIL 286
           LDELTL RTD E+Q E L EE+ YL+KNHEEEM AL+   GG+VNVEM+AAPGVDL+ +L
Sbjct: 200 LDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLAVLL 259

Query: 287 NEMRDQYEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIE 346
           N MR +YE +AE+NR+DAE WF  K+  L ++++ +S     +RS++TE+RR LQ LEI+
Sbjct: 260 NNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQ 319

Query: 347 LQSQLSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDV 406
           LQS ++ K SLE SL ET+  YC QL+QIQ  IG++EEQL Q+R E E Q  EY+ LLDV
Sbjct: 320 LQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDV 379

Query: 407 KTRLEQEIATYRRLLEGEDAHLSSQQASG 435
           K  LE+EI TY RL++G+    S  +  G
Sbjct: 380 KVHLEKEIETYCRLIDGDGNSCSKSKGFG 408


>gi|94538345 keratin 35 [Homo sapiens]
          Length = 455

 Score =  402 bits (1034), Expect = e-112
 Identities = 220/428 (51%), Positives = 298/428 (69%), Gaps = 27/428 (6%)

Query: 4   CSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSGGACG 63
           C +   SS S+K      GG  GGS+R+S++ +  SC+ PS     LS  +R  S  + G
Sbjct: 5   CLKAGFSSGSLKSP----GGASGGSTRVSAMYSSSSCKLPS-----LSPVARSFSACSVG 55

Query: 64  LGGGYGGGFSSSSSF---GSGFGGGYGGGLGAGFGGGLGAGFGGGFAGGDGLLVGSEKVT 120
           LG       S   +      GF   Y GG             GG F  G+G+L G+EK T
Sbjct: 56  LGRSSYRATSCLPALCLPAGGFATSYSGG-------------GGWF--GEGILTGNEKET 100

Query: 121 MQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIKDYSPYFKTIEDLRNKIIA 180
           MQ+LNDRLA YL+KVR LE+ NA LE +IR+W ++Q P    DY  YF+TIE+L+ K + 
Sbjct: 101 MQSLNDRLAGYLEKVRQLEQENASLESRIREWCEQQVPYMCPDYQSYFRTIEELQKKTLC 160

Query: 181 ATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDELTLARTDLEMQ 240
           +  ENA+ +++IDNA+LAADDFRTKYE E++LRQ VE+D+NGLRR+LD+LTL ++DLE Q
Sbjct: 161 SKAENARLVVEIDNAKLAADDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQ 220

Query: 241 IEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEKN 300
           +E LKEEL  L+KNHEEE+ +LR Q G  +NVE+DAAP VDL+R+L EMR QYE + E N
Sbjct: 221 VESLKEELLCLKKNHEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENN 280

Query: 301 RRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQSQLSMKASLENS 360
           RRDAE W  +++EELN++V S+SE +QS ++E+ ELRR +  LEIELQ+Q SM+ +LE++
Sbjct: 281 RRDAEDWLDTQSEELNQQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALEST 340

Query: 361 LEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLEQEIATYRRL 420
           L ET+ RY  QL+Q+Q +I +VE QLA++R ++E+Q+QEYQ+LLDV+ RLE EI TYR L
Sbjct: 341 LAETEARYSSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGL 400

Query: 421 LEGEDAHL 428
           LE ED+ L
Sbjct: 401 LESEDSKL 408


>gi|31559815 keratin 26 [Homo sapiens]
          Length = 468

 Score =  386 bits (992), Expect = e-107
 Identities = 220/409 (53%), Positives = 272/409 (66%), Gaps = 10/409 (2%)

Query: 35  LAGGSCRAPSTYGGGLSVSSRFSSGGACGLGGGYGGGFSSSSSFGSGFGGGYGGGLGAGF 94
           L+GGS R  S  G G     R S GG   + G    G  + SSF     G   GG     
Sbjct: 5   LSGGSRRICSRTGSG-----RLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNS 59

Query: 95  GGGLGAGFGGGFAGGD-GLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWY 153
           GGGLG+G   GF G +  LL G+EKVTMQNLNDRLASYLD V ALEEANADLE KI+  Y
Sbjct: 60  GGGLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRY 119

Query: 154 QRQRPSEIK----DYSPYFKTIEDLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHE 209
           ++  P   +    DYS YF  IEDL+ +I +ATI NA  +LQ DNARL ADDFR KYE+E
Sbjct: 120 EKCEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENE 179

Query: 210 LALRQTVEADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGD 269
           LAL  +VEAD +GLRRVLDELTL  TDLE+Q E L EEL YL+K+HEEEM  L+   GG+
Sbjct: 180 LALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGN 239

Query: 270 VNVEMDAAPGVDLSRILNEMRDQYEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSS 329
           VNVEM+A PGVDL+ +LN MR +YE +AE+NR+DAE WF  ++  L ++++ +     ++
Sbjct: 240 VNVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAA 299

Query: 330 RSEVTELRRVLQGLEIELQSQLSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQL 389
           R+E+TEL+R LQ LEIELQS +++K S E SL ET+G YC QL QIQ  IG +EEQL Q+
Sbjct: 300 RNELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQI 359

Query: 390 RCEMEQQSQEYQILLDVKTRLEQEIATYRRLLEGEDAHLSSQQASGQSY 438
           R E E Q  EY+ LLDVK  LE+EI  Y  LL+GE+    S     + Y
Sbjct: 360 RTETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERKSKSTCYKSKGY 408


>gi|14917115 keratin 31 [Homo sapiens]
          Length = 416

 Score =  375 bits (964), Expect = e-104
 Identities = 193/334 (57%), Positives = 253/334 (75%)

Query: 110 DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIKDYSPYFK 169
           +G   GSEK TMQ LNDRLASYL+KVR LE  NA+LE  IR+  Q+Q P     Y  YFK
Sbjct: 49  EGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFK 108

Query: 170 TIEDLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDE 229
           TIE+L+ KI+    ENA+ ++QIDNA+LAADDFRTKY+ EL+LRQ VE+D+NGLRR+LDE
Sbjct: 109 TIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDE 168

Query: 230 LTLARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEM 289
           LTL ++DLE Q+E LKEEL  L+ NHE+E+  LR Q G  +NVE+DAAP VDL+R+LNE 
Sbjct: 169 LTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNET 228

Query: 290 RDQYEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQS 349
           R QYE + E NRR+ E WF ++TEELNK+V S+SE +QS ++E+ ELRR +  LEIELQ+
Sbjct: 229 RSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQA 288

Query: 350 QLSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTR 409
           Q +++ SLEN+L E++ RY  QLSQ+Q LI +VE QLA++R ++E+Q+QEYQ+LLDV+ R
Sbjct: 289 QHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRAR 348

Query: 410 LEQEIATYRRLLEGEDAHLSSQQASGQSYSSREV 443
           LE EI TYR LLE ED +L S   +  +  S+ +
Sbjct: 349 LECEINTYRSLLESEDCNLPSNPCATTNACSKPI 382


>gi|14917117 keratin 33A [Homo sapiens]
          Length = 404

 Score =  374 bits (959), Expect = e-103
 Identities = 192/321 (59%), Positives = 249/321 (77%)

Query: 110 DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIKDYSPYFK 169
           +G   GSEK TMQ LNDRLASYL+KVR LE  NA+LE  IR+  Q+Q P     Y  YFK
Sbjct: 49  EGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFK 108

Query: 170 TIEDLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDE 229
           TIE+L+ KI+ +  ENA+ ++QIDNA+LA+DDFRTKYE EL+LRQ VE+D+NGLRR+LDE
Sbjct: 109 TIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDE 168

Query: 230 LTLARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEM 289
           LTL R+DLE Q+E LKEEL  L++NHE+E+  LR Q G  +NVE+DAAP VDL+++LNE 
Sbjct: 169 LTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNET 228

Query: 290 RDQYEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQS 349
           R QYE + E NRR+ E WF ++TEELNK+V S+SE +QS ++E+ ELRR +  LEIELQ+
Sbjct: 229 RSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQA 288

Query: 350 QLSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTR 409
           Q +++ SLEN+L E++ RY  QLSQ+Q LI +VE QLA++R ++E+Q+QEYQ+LLDV+ R
Sbjct: 289 QHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRAR 348

Query: 410 LEQEIATYRRLLEGEDAHLSS 430
           LE EI TYR LLE ED  L S
Sbjct: 349 LECEINTYRSLLESEDCKLPS 369


>gi|10337581 type I hair keratin 3B [Homo sapiens]
          Length = 404

 Score =  370 bits (949), Expect = e-102
 Identities = 190/321 (59%), Positives = 248/321 (77%)

Query: 110 DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIKDYSPYFK 169
           +G   GSEK TMQ LNDRLASYL+KVR LE  NA+LE  IR+  Q+Q P     Y  YFK
Sbjct: 49  EGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFK 108

Query: 170 TIEDLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDE 229
           TIE+L+ KI+ +  ENA+ ++QIDNA+LAADDFRTKY+ E +LRQ VE+D+N LRR+LDE
Sbjct: 109 TIEELQQKILCSKSENARLVVQIDNAKLAADDFRTKYQTEQSLRQLVESDINSLRRILDE 168

Query: 230 LTLARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEM 289
           LTL R+DLE Q+E LKEEL  L++NHE+E+  LR Q G  +NVE+DAAP VDL+++LNE 
Sbjct: 169 LTLCRSDLEAQMESLKEELLSLKQNHEQEVNTLRCQLGDRLNVEVDAAPAVDLNQVLNET 228

Query: 290 RDQYEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQS 349
           R+QYE + E NRR+ E WF ++TEELNK+V S+SE +QS ++E+ ELRR +  LEIELQ+
Sbjct: 229 RNQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQA 288

Query: 350 QLSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTR 409
           Q +++ SLEN+L E++ RY  QLSQ+Q LI +VE QLA++R ++E+Q+QEYQ+LLDV+ R
Sbjct: 289 QHNLRYSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRAR 348

Query: 410 LEQEIATYRRLLEGEDAHLSS 430
           LE EI TYR LLE ED  L S
Sbjct: 349 LECEINTYRSLLESEDCKLPS 369


>gi|27894337 keratin 20 [Homo sapiens]
          Length = 424

 Score =  367 bits (942), Expect = e-101
 Identities = 191/352 (54%), Positives = 253/352 (71%), Gaps = 3/352 (0%)

Query: 86  YGGGLGAGF---GGGLGAGFGGGFAGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEAN 142
           YGG  G G           +G    GG  L VG+EK+ MQNLNDRLASYL+KVR LE++N
Sbjct: 36  YGGAGGRGIRISNSRHTVNYGSDLTGGGDLFVGNEKMAMQNLNDRLASYLEKVRTLEQSN 95

Query: 143 ADLEVKIRDWYQRQRPSEIKDYSPYFKTIEDLRNKIIAATIENAQPILQIDNARLAADDF 202
           + LEV+I+ WY+   P   +DYS Y++ IE+LR++I  A ++NA+ +LQIDNA+LAA+DF
Sbjct: 96  SKLEVQIKQWYETNAPRAGRDYSAYYRQIEELRSQIKDAQLQNARCVLQIDNAKLAAEDF 155

Query: 203 RTKYEHELALRQTVEADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLRKNHEEEMLAL 262
           R KYE E  +R TVEAD+ GL +V D+LTL +TDLE+QIE L ++LA L+K H+EE+  L
Sbjct: 156 RLKYETERGIRLTVEADLQGLNKVFDDLTLHKTDLEIQIEELNKDLALLKKEHQEEVDGL 215

Query: 263 RGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEKNRRDAETWFLSKTEELNKEVASN 322
               G  VNVE+DAAPG++L  I+NEMR +YE MA+KN ++A+  F  +T  L ++V  N
Sbjct: 216 HKHLGNTVNVEVDAAPGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTVN 275

Query: 323 SELVQSSRSEVTELRRVLQGLEIELQSQLSMKASLENSLEETKGRYCMQLSQIQGLIGSV 382
           +E ++ +  ++TELRR  Q LEIELQS LSMK SLE++LEETK RY  QL+ +Q L+ S+
Sbjct: 276 TEELKGTEVQLTELRRTSQSLEIELQSHLSMKESLEHTLEETKARYSSQLANLQSLLSSL 335

Query: 383 EEQLAQLRCEMEQQSQEYQILLDVKTRLEQEIATYRRLLEGEDAHLSSQQAS 434
           E QL Q+R  ME+Q+ EY ILLD+KTRLEQEIATYRRLLEGED   +  Q S
Sbjct: 336 EAQLMQIRSNMERQNNEYHILLDIKTRLEQEIATYRRLLEGEDVKTTEYQLS 387


>gi|14917119 keratin 34 [Homo sapiens]
          Length = 436

 Score =  363 bits (932), Expect = e-100
 Identities = 187/333 (56%), Positives = 249/333 (74%), Gaps = 5/333 (1%)

Query: 110 DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIKDYSPYFK 169
           +G   GSEK TMQ LNDRLASYL+KVR LE  NA+LE  I++  Q+Q P     Y  YFK
Sbjct: 91  EGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELEKLIQERSQQQEPLLCPSYQSYFK 150

Query: 170 TIEDLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDE 229
           TIE+L+ KI+ A  ENA+ ++ IDNA+LA+DDFR+KY+ E +LR  VE+D+N +RR+LDE
Sbjct: 151 TIEELQQKILCAKAENARLVVNIDNAKLASDDFRSKYQTEQSLRLLVESDINSIRRILDE 210

Query: 230 LTLARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEM 289
           LTL ++DLE Q+E L+EEL  L+KNHEEE+  LR Q G  +NVE+D AP VDL+++LNE 
Sbjct: 211 LTLCKSDLESQVESLREELICLKKNHEEEVNTLRSQLGDRLNVEVDTAPTVDLNQVLNET 270

Query: 290 RDQYEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQS 349
           R QYE + E NRR+ E WF ++TEELNK+V S+SE +QS ++E+ ELRR +  LEIELQ+
Sbjct: 271 RSQYEALVEINRREVEQWFATQTEELNKQVVSSSEQLQSCQAEIIELRRTVNALEIELQA 330

Query: 350 QLSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTR 409
           Q +++ SLEN+L E++  Y  QLSQ+Q LI +VE QLA++RC++E+Q+QEYQ+LLDV+ R
Sbjct: 331 QHNLRDSLENTLTESEAHYSSQLSQVQSLITNVESQLAEIRCDLERQNQEYQVLLDVRAR 390

Query: 410 LEQEIATYRRLLEGEDAHL-----SSQQASGQS 437
           LE EI TYR LLE ED  L     ++  ASG S
Sbjct: 391 LECEINTYRSLLESEDCKLPCNPCATTNASGNS 423


>gi|116488398 keratin 32 [Homo sapiens]
          Length = 448

 Score =  360 bits (925), Expect = 1e-99
 Identities = 187/341 (54%), Positives = 250/341 (73%)

Query: 97  GLGAGFGGGFAGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQ 156
           G+    G G    +G   G+EK TMQ LNDRLASYL +VR LE+ NA+LE +I++    Q
Sbjct: 76  GISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQENAELESRIQEASHSQ 135

Query: 157 RPSEIKDYSPYFKTIEDLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHELALRQTV 216
             +   DY  +F+TIE+L+ KI+    ENA+ ++ IDNA+LAADDFR KYE ELA+RQ V
Sbjct: 136 VLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDFRAKYEAELAMRQLV 195

Query: 217 EADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDA 276
           EAD+NGLRR+LD+LTL + DLE Q+E LKEEL  L+KNHEEE+ +LR Q G  +N+E+DA
Sbjct: 196 EADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQLGDRLNIEVDA 255

Query: 277 APGVDLSRILNEMRDQYEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTEL 336
           AP VDL+R+L EMR QYE M E NRRD E WF  + EELN++VA++SE +Q+ +S++ +L
Sbjct: 256 APPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQLQNYQSDIIDL 315

Query: 337 RRVLQGLEIELQSQLSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQ 396
           RR +  LEIELQ+Q S++ SLEN+L E++ RY  QL+Q+Q +I +VE QLA++R ++E+Q
Sbjct: 316 RRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEIRADLERQ 375

Query: 397 SQEYQILLDVKTRLEQEIATYRRLLEGEDAHLSSQQASGQS 437
           +QEYQ+LLDV+ RLE EI TYR LLE ED  L     S  S
Sbjct: 376 NQEYQVLLDVRARLEGEINTYRSLLENEDCKLPCNPCSTPS 416


>gi|40354195 keratin 18 [Homo sapiens]
          Length = 430

 Score =  339 bits (870), Expect = 3e-93
 Identities = 195/412 (47%), Positives = 273/412 (66%), Gaps = 21/412 (5%)

Query: 38  GSCRAPSTYGGGLSVSSRFSSGGACGLGGGYGGGFSSSSSFGSGFGGGYG-GGLGAGFGG 96
           GS +APS YG      +R  S  A    G  G G   S S  + F GG G GGL  G  G
Sbjct: 17  GSVQAPS-YG------ARPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGSGGLATGIAG 69

Query: 97  GLGAGFGGGFAGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQ 156
           GL AG GG         + +EK TMQ+LNDRLASYLD+VR+LE  N  LE KIR+  +++
Sbjct: 70  GL-AGMGG---------IQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKK 119

Query: 157 RPSEIKDYSPYFKTIEDLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHELALRQTV 216
            P +++D+S YFK IEDLR +I A T++NA+ +LQIDNARLAADDFR KYE ELA+RQ+V
Sbjct: 120 GP-QVRDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSV 178

Query: 217 EADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGD-VNVEMD 275
           E D++GLR+V+D+  + R  LE +IE LKEEL +++KNHEEE+  L+ Q     + VE+D
Sbjct: 179 ENDIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVD 238

Query: 276 AAPGVDLSRILNEMRDQYEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTE 335
           A    DL++I+ ++R QY+++A KNR + + ++  + EE    V + S  V ++ + +TE
Sbjct: 239 APKSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTE 298

Query: 336 LRRVLQGLEIELQSQLSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQ 395
           LRR +Q LEI+L S  ++KASLENSL E + RY +Q+ Q+ G++  +E +LAQ R E ++
Sbjct: 299 LRRTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQR 358

Query: 396 QSQEYQILLDVKTRLEQEIATYRRLLE-GEDAHLSSQQASGQSYSSREVFTS 446
           Q+QEY+ LL++K +LE EIATYRRLLE GED +L     S  S  + +  T+
Sbjct: 359 QAQEYEALLNIKVKLEAEIATYRRLLEDGEDFNLGDALDSSNSMQTIQKTTT 410


>gi|4557888 keratin 18 [Homo sapiens]
          Length = 430

 Score =  339 bits (870), Expect = 3e-93
 Identities = 195/412 (47%), Positives = 273/412 (66%), Gaps = 21/412 (5%)

Query: 38  GSCRAPSTYGGGLSVSSRFSSGGACGLGGGYGGGFSSSSSFGSGFGGGYG-GGLGAGFGG 96
           GS +APS YG      +R  S  A    G  G G   S S  + F GG G GGL  G  G
Sbjct: 17  GSVQAPS-YG------ARPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGSGGLATGIAG 69

Query: 97  GLGAGFGGGFAGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQ 156
           GL AG GG         + +EK TMQ+LNDRLASYLD+VR+LE  N  LE KIR+  +++
Sbjct: 70  GL-AGMGG---------IQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKK 119

Query: 157 RPSEIKDYSPYFKTIEDLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHELALRQTV 216
            P +++D+S YFK IEDLR +I A T++NA+ +LQIDNARLAADDFR KYE ELA+RQ+V
Sbjct: 120 GP-QVRDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSV 178

Query: 217 EADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGD-VNVEMD 275
           E D++GLR+V+D+  + R  LE +IE LKEEL +++KNHEEE+  L+ Q     + VE+D
Sbjct: 179 ENDIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVD 238

Query: 276 AAPGVDLSRILNEMRDQYEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTE 335
           A    DL++I+ ++R QY+++A KNR + + ++  + EE    V + S  V ++ + +TE
Sbjct: 239 APKSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTE 298

Query: 336 LRRVLQGLEIELQSQLSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQ 395
           LRR +Q LEI+L S  ++KASLENSL E + RY +Q+ Q+ G++  +E +LAQ R E ++
Sbjct: 299 LRRTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQR 358

Query: 396 QSQEYQILLDVKTRLEQEIATYRRLLE-GEDAHLSSQQASGQSYSSREVFTS 446
           Q+QEY+ LL++K +LE EIATYRRLLE GED +L     S  S  + +  T+
Sbjct: 359 QAQEYEALLNIKVKLEAEIATYRRLLEDGEDFNLGDALDSSNSMQTIQKTTT 410


>gi|125490370 type I hair keratin KA36 [Homo sapiens]
          Length = 431

 Score =  333 bits (854), Expect = 2e-91
 Identities = 171/331 (51%), Positives = 238/331 (71%)

Query: 110 DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIKDYSPYFK 169
           DG+   +EK TMQ LNDRLASYL+KVR+LEE NA+LE +I++  ++  P    DY  YF 
Sbjct: 82  DGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPMVCPDYQRYFN 141

Query: 170 TIEDLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDE 229
           TIEDL+ KI+    EN++  +Q+DN +LA DDF++KYE EL+LRQ +EAD++ L  +L+E
Sbjct: 142 TIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLHGILEE 201

Query: 230 LTLARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEM 289
           LTL ++DLE  +E LKE+L  L+KNHEEE+  LR Q G  ++VE+D AP +DL+R+L+EM
Sbjct: 202 LTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDLNRVLDEM 261

Query: 290 RDQYEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQS 349
           R Q E +   NRR+AE W   +TEELN++  S++E +Q  + E+ EL+R    LEIELQ+
Sbjct: 262 RCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASALEIELQA 321

Query: 350 QLSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTR 409
           Q S+  SLE ++ ET+ +Y  QL+QIQ LI ++E QLA++RC++E+Q+QEYQ+LLDVK R
Sbjct: 322 QQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVLLDVKAR 381

Query: 410 LEQEIATYRRLLEGEDAHLSSQQASGQSYSS 440
           LE EI TY  LL+ ED+ LS    S    SS
Sbjct: 382 LEGEINTYWGLLDSEDSRLSCSPCSTTCTSS 412


>gi|15431318 keratin 38 [Homo sapiens]
          Length = 456

 Score =  318 bits (814), Expect = 9e-87
 Identities = 168/328 (51%), Positives = 229/328 (69%)

Query: 107 AGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIKDYSP 166
           A G+  L G EK TMQ LNDRLA+YL+KVR LE+ NA+LE  + +  +    +   DY  
Sbjct: 94  AYGENTLNGHEKETMQFLNDRLANYLEKVRQLEQENAELEATLLERSKCHESTVCPDYQS 153

Query: 167 YFKTIEDLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRV 226
           YF TIE+L+ KI+ +  ENA+ I+QIDNA+LAADDFR K E E +LRQ VEAD  G +++
Sbjct: 154 YFHTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLRQLVEADKCGTQKL 213

Query: 227 LDELTLARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRIL 286
           LD+ TLA+ DLE Q E LKEE   L+ NHE+E+  LR Q G  + +E+D  P +DL+R+L
Sbjct: 214 LDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKLRIELDIEPTIDLNRVL 273

Query: 287 NEMRDQYEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIE 346
            EMR QYE M E NR+D E WF +++E ++ +  S SE +Q  +SE+ ELR  +  LE+E
Sbjct: 274 GEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSEILELRCTVNALEVE 333

Query: 347 LQSQLSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDV 406
            Q+Q ++K  L+NSL E + R+  +L+Q+Q LI +VEEQL+++R ++E+Q+QEYQ+LLDV
Sbjct: 334 RQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLERQNQEYQVLLDV 393

Query: 407 KTRLEQEIATYRRLLEGEDAHLSSQQAS 434
           KTRLE EIATYR LLE ED  L     S
Sbjct: 394 KTRLENEIATYRNLLESEDCKLPCNPCS 421


>gi|27894339 keratin 23 [Homo sapiens]
          Length = 422

 Score =  317 bits (811), Expect = 2e-86
 Identities = 172/385 (44%), Positives = 242/385 (62%), Gaps = 18/385 (4%)

Query: 67  GYGGGFSSSSSFGSG---FGGGYGGGLGAGF--------GGGLGAGFGGGFAGGDGLLVG 115
           G GGG+    SF       GG  G  +   F        GG  G+G      GG+G    
Sbjct: 17  GAGGGWGRPRSFPRAPTVHGGAGGARISLSFTTRSCPPPGGSWGSGRSSPLLGGNG---- 72

Query: 116 SEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIKDYSPYFKTIEDLR 175
             K TMQNLNDRLASYL+KVRALEEAN  LE +I  W+Q++ P   KDYS Y + I  L+
Sbjct: 73  --KATMQNLNDRLASYLEKVRALEEANMKLESRILKWHQQRDPGSKKDYSQYEENITHLQ 130

Query: 176 NKIIAATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDELTLART 235
            +I+   + NAQ IL IDNAR+A DDF  KYE+E + ++ +E +V GLRR LD LT+  T
Sbjct: 131 EQIVDGKMTNAQIILLIDNARMAVDDFNLKYENEHSFKKDLEIEVEGLRRTLDNLTIVTT 190

Query: 236 DLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQ 295
           DLE ++EG+++EL  ++K+HE+EM      +  +VNV++D  P  DL ++L +MR +YE 
Sbjct: 191 DLEQEVEGMRKELILMKKHHEQEMEKHHVPSDFNVNVKVDTGPREDLIKVLEDMRQEYEL 250

Query: 296 MAEKNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQSQLSMKA 355
           + +K  RD +TW+  ++  +++E AS +  VQS + ++ EL+R  Q LEI+LQ+Q S K+
Sbjct: 251 IIKKKHRDLDTWYKEQSAAMSQEAASPA-TVQSRQGDIHELKRTFQALEIDLQTQYSTKS 309

Query: 356 SLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLEQEIA 415
           +LEN L ET+ RY  +L  +Q +I   EE+L QLR E+E+Q+ EYQ+LL +KT LE+EI 
Sbjct: 310 ALENMLSETQSRYSCKLQDMQEIISHYEEELTQLRHELERQNNEYQVLLGIKTHLEKEIT 369

Query: 416 TYRRLLEGEDAHLSSQQASGQSYSS 440
           TYRRLLEGE      +  S    S+
Sbjct: 370 TYRRLLEGESEGTREESKSSMKVSA 394


>gi|148277620 type I hair keratin KA35 [Homo sapiens]
          Length = 491

 Score =  313 bits (801), Expect = 3e-85
 Identities = 169/361 (46%), Positives = 240/361 (66%), Gaps = 3/361 (0%)

Query: 109 GDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIKDYSPYF 168
           G+G+   +EK TMQ LN+RLA+YL KVR LE  NA+LE KI++   ++ P    DY  Y+
Sbjct: 89  GEGIN-SNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCPDYLSYY 147

Query: 169 KTIEDLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLD 228
            TIE+L+ KI+    EN++ + QIDN +L ADD R KYE E++LRQ VE+D NGL+++L+
Sbjct: 148 TTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQILN 207

Query: 229 ELTLARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNE 288
            LTL + DLE Q++ LKEEL  L+ NH+EE+ +L+ Q G  +++E+ AAP  DL+++L E
Sbjct: 208 VLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVLQE 267

Query: 289 MRDQYEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQ 348
           MR QYE + E NR+D E WF ++ EELN++V ++S+  Q  + E+ ELRR +  LE+ELQ
Sbjct: 268 MRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVELQ 327

Query: 349 SQLSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKT 408
           +Q  M+ S E  L ET+ RY   L+QIQ LI ++E QLA++RC +E+Q+QEY+ILLDVK+
Sbjct: 328 AQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDVKS 387

Query: 409 RLEQEIATYRRLLEGEDAHLSSQQASGQSYSSREVFTSSSSSSSRQTRPILKEQSSSSFS 468
           RLE EI TYR LLE  D        + +   S   +TS  S +   T P     S  S  
Sbjct: 388 RLECEITTYRSLLESSDGKRPCYPRATKCEPS--PWTSCKSGAIESTAPACTSSSPCSLK 445

Query: 469 Q 469
           +
Sbjct: 446 E 446


>gi|55770882 keratin 37 [Homo sapiens]
          Length = 449

 Score =  311 bits (798), Expect = 6e-85
 Identities = 164/328 (50%), Positives = 225/328 (68%)

Query: 107 AGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIKDYSP 166
           A G   L G EK TM+ LNDRLA+YL+KVR LE+ NA+LE  + +  +    +   DY  
Sbjct: 94  AYGKNTLNGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLERSKCHESTVCPDYQS 153

Query: 167 YFKTIEDLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRV 226
           YF+TIE+L+ KI+ +  ENA+ I+QIDNA+LAADDFR K E E +L Q VEAD  G +++
Sbjct: 154 YFRTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLVEADKCGTQKL 213

Query: 227 LDELTLARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRIL 286
           LD+ TLA+ DLE Q E LKEE   L+ NHE+E+  LR Q G    +E+D  P +DL+R+L
Sbjct: 214 LDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRIELDIEPTIDLNRVL 273

Query: 287 NEMRDQYEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIE 346
            EMR QYE M E N +D E WF +++E ++ +  S SE +Q  +SE+ ELR  +  LE+E
Sbjct: 274 GEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILELRCTVNALEVE 333

Query: 347 LQSQLSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDV 406
            Q+Q ++K  L+NSL E + RY  +L+Q+Q LI ++EEQL+++R ++E+Q+QEYQ+LLDV
Sbjct: 334 RQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQNQEYQVLLDV 393

Query: 407 KTRLEQEIATYRRLLEGEDAHLSSQQAS 434
           K RLE EIATYR LLE ED  L     S
Sbjct: 394 KARLENEIATYRNLLESEDCKLPCNPCS 421


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.129    0.353 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,097,630
Number of Sequences: 37866
Number of extensions: 808973
Number of successful extensions: 21369
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 475
Number of HSP's successfully gapped in prelim test: 581
Number of HSP's that attempted gapping in prelim test: 6885
Number of HSP's gapped (non-prelim): 6008
length of query: 473
length of database: 18,247,518
effective HSP length: 106
effective length of query: 367
effective length of database: 14,233,722
effective search space: 5223775974
effective search space used: 5223775974
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.