Guide to the Human Genome
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Search of human proteins with 24430190

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24430190 keratin 15 [Homo sapiens]
         (456 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|24430190 keratin 15 [Homo sapiens]                                 893   0.0  
gi|131412225 keratin 13 isoform a [Homo sapiens]                      638   0.0  
gi|131412228 keratin 13 isoform b [Homo sapiens]                      634   0.0  
gi|15431310 keratin 14 [Homo sapiens]                                 559   e-159
gi|24430192 keratin 16 [Homo sapiens]                                 553   e-157
gi|4557701 keratin 17 [Homo sapiens]                                  516   e-146
gi|24234699 keratin 19 [Homo sapiens]                                 496   e-140
gi|195972866 keratin 10 [Homo sapiens]                                488   e-138
gi|4557699 keratin 12 [Homo sapiens]                                  473   e-133
gi|192807292 keratin 24 [Homo sapiens]                                439   e-123
gi|55956899 keratin 9 [Homo sapiens]                                  438   e-123
gi|114431246 keratin 25D [Homo sapiens]                               415   e-116
gi|153945736 keratin 27 [Homo sapiens]                                413   e-115
gi|31559829 keratin 25 [Homo sapiens]                                 401   e-112
gi|4504927 keratin 36 [Homo sapiens]                                  400   e-111
gi|94538345 keratin 35 [Homo sapiens]                                 384   e-107
gi|31559815 keratin 26 [Homo sapiens]                                 376   e-104
gi|116488398 keratin 32 [Homo sapiens]                                370   e-102
gi|27894337 keratin 20 [Homo sapiens]                                 367   e-101
gi|14917117 keratin 33A [Homo sapiens]                                360   1e-99
gi|14917115 keratin 31 [Homo sapiens]                                 360   1e-99
gi|10337581 type I hair keratin 3B [Homo sapiens]                     356   2e-98
gi|14917119 keratin 34 [Homo sapiens]                                 354   8e-98
gi|40354195 keratin 18 [Homo sapiens]                                 335   4e-92
gi|4557888 keratin 18 [Homo sapiens]                                  335   4e-92
gi|125490370 type I hair keratin KA36 [Homo sapiens]                  323   2e-88
gi|148277620 type I hair keratin KA35 [Homo sapiens]                  320   2e-87
gi|15431318 keratin 38 [Homo sapiens]                                 319   3e-87
gi|27894339 keratin 23 [Homo sapiens]                                 319   4e-87
gi|55770882 keratin 37 [Homo sapiens]                                 317   2e-86

>gi|24430190 keratin 15 [Homo sapiens]
          Length = 456

 Score =  893 bits (2308), Expect = 0.0
 Identities = 456/456 (100%), Positives = 456/456 (100%)

Query: 1   MTTTFLQTSSSTFGGGSTRGGSLLAGGGGFGGGSLSGGGGSRSISASSARFVSSGSGGGY 60
           MTTTFLQTSSSTFGGGSTRGGSLLAGGGGFGGGSLSGGGGSRSISASSARFVSSGSGGGY
Sbjct: 1   MTTTFLQTSSSTFGGGSTRGGSLLAGGGGFGGGSLSGGGGSRSISASSARFVSSGSGGGY 60

Query: 61  GGGMRVCGFGGGAGSVFGGGFGGGVGGGFGGGFGGGDGGLLSGNEKITMQNLNDRLASYL 120
           GGGMRVCGFGGGAGSVFGGGFGGGVGGGFGGGFGGGDGGLLSGNEKITMQNLNDRLASYL
Sbjct: 61  GGGMRVCGFGGGAGSVFGGGFGGGVGGGFGGGFGGGDGGLLSGNEKITMQNLNDRLASYL 120

Query: 121 DKVRALEEANADLEVKIHDWYQKQTPTSPECDYSQYFKTIEELRDKIMATTIDNSRVILE 180
           DKVRALEEANADLEVKIHDWYQKQTPTSPECDYSQYFKTIEELRDKIMATTIDNSRVILE
Sbjct: 121 DKVRALEEANADLEVKIHDWYQKQTPTSPECDYSQYFKTIEELRDKIMATTIDNSRVILE 180

Query: 181 IDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNEELAYL 240
           IDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNEELAYL
Sbjct: 181 IDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNEELAYL 240

Query: 241 KKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEKNRRDVEAWFFSK 300
           KKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEKNRRDVEAWFFSK
Sbjct: 241 KKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEKNRRDVEAWFFSK 300

Query: 301 TEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQSQLSMKAGLENSLAETECRYATQ 360
           TEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQSQLSMKAGLENSLAETECRYATQ
Sbjct: 301 TEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQSQLSMKAGLENSLAETECRYATQ 360

Query: 361 LQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMAGI 420
           LQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMAGI
Sbjct: 361 LQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMAGI 420

Query: 421 GIREASSGGGGSSSNFHINVEESVDGQVVSSHKREI 456
           GIREASSGGGGSSSNFHINVEESVDGQVVSSHKREI
Sbjct: 421 GIREASSGGGGSSSNFHINVEESVDGQVVSSHKREI 456


>gi|131412225 keratin 13 isoform a [Homo sapiens]
          Length = 458

 Score =  638 bits (1646), Expect = 0.0
 Identities = 333/440 (75%), Positives = 365/440 (82%), Gaps = 21/440 (4%)

Query: 27  GGGFGGGSLSGGGGSRSISASSARFVSSGSGGGYGGGMRVCGFGGGAGSVFGGGFGGGVG 86
           GGGFGGGS   GGG R +S  S RFVS GS GGYGGG+  CGFGGGAGS FGGG+GGG+G
Sbjct: 13  GGGFGGGSCQLGGG-RGVSTCSTRFVSGGSAGGYGGGVS-CGFGGGAGSGFGGGYGGGLG 70

Query: 87  GGFGGGFGGG---------------DGGLLSGNEKITMQNLNDRLASYLDKVRALEEANA 131
           GG+GGG GGG               DGGLL+GNEKITMQNLNDRLASYL+KVRALEEANA
Sbjct: 71  GGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANA 130

Query: 132 DLEVKIHDWYQKQTPTSPECDYSQYFKTIEELRDKIMATTIDNSRVILEIDNARLAADDF 191
           DLEVKI DW+ KQ+P SPE DYS Y+KTIEELRDKI+  TI+N+RVILEIDNARLAADDF
Sbjct: 131 DLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDF 190

Query: 192 RLKYENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNEELAYLKKNHEEEMKEF 251
           RLKYENELALRQ VEADINGLRRVLDELTL++TDLEMQIE LNEELAY+KKNHEEEMKEF
Sbjct: 191 RLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEF 250

Query: 252 SSQLAGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEKNRRDVEAWFFSKTEELNKEVASN 311
           S+Q+ GQVNVEMDA PG+DLTRVLAEMREQYEAMAE+NRRD E WF +K+ ELNKEV++N
Sbjct: 251 SNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTN 310

Query: 312 TEMIQTSKTEITDLRRTMQELEIELQSQLSMKAGLENSLAETECRYATQLQQIQGLIGGL 371
           T MIQTSKTEIT+LRRT+Q LEIELQSQLSMKAGLEN++AETECRYA QLQQIQGLI  +
Sbjct: 311 TAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSI 370

Query: 372 EAQLSELRCEMEAQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMAGIGIREASSGGGG 431
           EAQLSELR EME QNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKM G      SS G  
Sbjct: 371 EAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMIGF----PSSAGSV 426

Query: 432 SSSNFHINVEESVDGQVVSS 451
           S  +  +    S      S+
Sbjct: 427 SPRSTSVTTTSSASVTTTSN 446


>gi|131412228 keratin 13 isoform b [Homo sapiens]
          Length = 420

 Score =  634 bits (1634), Expect = 0.0
 Identities = 325/405 (80%), Positives = 354/405 (87%), Gaps = 17/405 (4%)

Query: 27  GGGFGGGSLSGGGGSRSISASSARFVSSGSGGGYGGGMRVCGFGGGAGSVFGGGFGGGVG 86
           GGGFGGGS   GGG R +S  S RFVS GS GGYGGG+  CGFGGGAGS FGGG+GGG+G
Sbjct: 13  GGGFGGGSCQLGGG-RGVSTCSTRFVSGGSAGGYGGGVS-CGFGGGAGSGFGGGYGGGLG 70

Query: 87  GGFGGGFGGG---------------DGGLLSGNEKITMQNLNDRLASYLDKVRALEEANA 131
           GG+GGG GGG               DGGLL+GNEKITMQNLNDRLASYL+KVRALEEANA
Sbjct: 71  GGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANA 130

Query: 132 DLEVKIHDWYQKQTPTSPECDYSQYFKTIEELRDKIMATTIDNSRVILEIDNARLAADDF 191
           DLEVKI DW+ KQ+P SPE DYS Y+KTIEELRDKI+  TI+N+RVILEIDNARLAADDF
Sbjct: 131 DLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDF 190

Query: 192 RLKYENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNEELAYLKKNHEEEMKEF 251
           RLKYENELALRQ VEADINGLRRVLDELTL++TDLEMQIE LNEELAY+KKNHEEEMKEF
Sbjct: 191 RLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEF 250

Query: 252 SSQLAGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEKNRRDVEAWFFSKTEELNKEVASN 311
           S+Q+ GQVNVEMDA PG+DLTRVLAEMREQYEAMAE+NRRD E WF +K+ ELNKEV++N
Sbjct: 251 SNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTN 310

Query: 312 TEMIQTSKTEITDLRRTMQELEIELQSQLSMKAGLENSLAETECRYATQLQQIQGLIGGL 371
           T MIQTSKTEIT+LRRT+Q LEIELQSQLSMKAGLEN++AETECRYA QLQQIQGLI  +
Sbjct: 311 TAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSI 370

Query: 372 EAQLSELRCEMEAQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAK 416
           EAQLSELR EME QNQEYKMLLDIKTRLEQEIATYRSLLEGQDAK
Sbjct: 371 EAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAK 415


>gi|15431310 keratin 14 [Homo sapiens]
          Length = 472

 Score =  559 bits (1441), Expect = e-159
 Identities = 302/473 (63%), Positives = 353/473 (74%), Gaps = 26/473 (5%)

Query: 1   MTTTFLQTSSST-----------FGGGSTRGGSLLAGGGGFGGGSLSGGGGSRSISASSA 49
           MTT   Q +SS+            GGGS+R  S+LAGG      +  GG     +S SS+
Sbjct: 1   MTTCSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGG-----LSVSSS 55

Query: 50  RFVSSGS---GGGYGGGMRVCG--FGGGAGSVFGGGFGGGVGGGFGGGFGGGDGGLLSGN 104
           RF S G+   GGGYGGG       FG G G  +GGG G G+GGGFGGGF GGDG LL G+
Sbjct: 56  RFSSGGAYGLGGGYGGGFSSSSSSFGSGFGGGYGGGLGAGLGGGFGGGFAGGDG-LLVGS 114

Query: 105 EKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPTSPECDYSQYFKTIEELR 164
           EK+TMQNLNDRLASYLDKVRALEEANADLEVKI DWYQ+Q P   + DYS YFKTIE+LR
Sbjct: 115 EKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIK-DYSPYFKTIEDLR 173

Query: 165 DKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTLART 224
           +KI+  T+DN+ V+L+IDNARLAADDFR KYE EL LR  VEADINGLRRVLDELTLAR 
Sbjct: 174 NKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARA 233

Query: 225 DLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMREQYEA 284
           DLEMQIE L EELAYLKKNHEEEM     Q+ G VNVEMDAAPGVDL+R+L EMR+QYE 
Sbjct: 234 DLEMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEK 293

Query: 285 MAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQSQLSMKA 344
           MAEKNR+D E WFF+KTEELN+EVA+N+E++Q+ K+EI++LRRTMQ LEIELQSQLSMKA
Sbjct: 294 MAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSMKA 353

Query: 345 GLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTRLEQEIA 404
            LENSL ET+ RY  QL QIQ +IG +E QL++LRCEME QNQEYK+LLD+KTRLEQEIA
Sbjct: 354 SLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIA 413

Query: 405 TYRSLLEGQDAKMAGIGIREASSGG---GGSSSNFHINVEESVDGQVVSSHKR 454
           TYR LLEG+DA ++       S        SS      V +  DG+VVS+H++
Sbjct: 414 TYRRLLEGEDAHLSSSQFSSGSQSSRDVTSSSRQIRTKVMDVHDGKVVSTHEQ 466


>gi|24430192 keratin 16 [Homo sapiens]
          Length = 473

 Score =  553 bits (1424), Expect = e-157
 Identities = 298/437 (68%), Positives = 344/437 (78%), Gaps = 27/437 (6%)

Query: 1   MTTTFLQTSSST-----------FGGGSTRGGSLLAGGGGFGGGSLSGGGGSRSISASSA 49
           MTT   Q +SS+            GGGS+R  S+LAGG      +  GG     +S SS 
Sbjct: 1   MTTCSRQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGG-----LSVSS- 54

Query: 50  RFVSSGS---GGGYGGGMRVC-----GFGGGAGSVFGGGFGGGVGGGFGGGFGGGDGGLL 101
           RF S G+   GGGYGGG         GFGGG G   G GFGGG+G GFGGGF GGDG LL
Sbjct: 55  RFSSGGACGLGGGYGGGFSSSSSFGSGFGGGYGGGLGAGFGGGLGAGFGGGFAGGDG-LL 113

Query: 102 SGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPTSPECDYSQYFKTIE 161
            G+EK+TMQNLNDRLASYLDKVRALEEANADLEVKI DWYQ+Q P+  + DYS YFKTIE
Sbjct: 114 VGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIK-DYSPYFKTIE 172

Query: 162 ELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTL 221
           +LR+KI+A TI+N++ IL+IDNARLAADDFR KYE+ELALRQ VEAD+NGLRRVLDELTL
Sbjct: 173 DLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDELTL 232

Query: 222 ARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMREQ 281
           ARTDLEMQIEGL EELAYL+KNHEEEM     Q  G VNVEMDAAPGVDL+R+L EMR+Q
Sbjct: 233 ARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQ 292

Query: 282 YEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQSQLS 341
           YE MAEKNRRD E WF SKTEELNKEVASN+E++Q+S++E+T+LRR +Q LEIELQSQLS
Sbjct: 293 YEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQSQLS 352

Query: 342 MKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTRLEQ 401
           MKA LENSL ET+ RY  QL QIQGLIG +E QL++LRCEME Q+QEY++LLD+KTRLEQ
Sbjct: 353 MKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLEQ 412

Query: 402 EIATYRSLLEGQDAKMA 418
           EIATYR LLEG+DA ++
Sbjct: 413 EIATYRRLLEGEDAHLS 429


>gi|4557701 keratin 17 [Homo sapiens]
          Length = 432

 Score =  516 bits (1330), Expect = e-146
 Identities = 282/459 (61%), Positives = 332/459 (72%), Gaps = 38/459 (8%)

Query: 1   MTTTFLQTSSSTFGGGSTRGGSLLAGGGGFGGGSLSGGGGSRSISASSARFVSSGSGGGY 60
           MTT+  Q +SS          S + G  G GGGS          S +S R       GG 
Sbjct: 1   MTTSIRQFTSS----------SSIKGSSGLGGGS----------SRTSCRL-----SGGL 35

Query: 61  GGGMRVCGFGGGAGSVFGGG-----FGGGVGGGFGGGFGGGDGGLLSGNEKITMQNLNDR 115
           G G    G  GG GS  GG      +  G GGG+G  FGG DG LL+G EK TMQNLNDR
Sbjct: 36  GAGSCRLGSAGGLGSTLGGSSYSSCYSFGSGGGYGSSFGGVDG-LLAGGEKATMQNLNDR 94

Query: 116 LASYLDKVRALEEANADLEVKIHDWYQKQTPTSPECDYSQYFKTIEELRDKIMATTIDNS 175
           LASYLDKVRALEEAN +LEVKI DWYQ+Q P  P  DYSQY++TIEEL++KI+  T+DN+
Sbjct: 95  LASYLDKVRALEEANTELEVKIRDWYQRQAP-GPARDYSQYYRTIEELQNKILTATVDNA 153

Query: 176 RVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNE 235
            ++L+IDNARLAADDFR K+E E ALR  VEADINGLRRVLDELTLAR DLEMQIE L E
Sbjct: 154 NILLQIDNARLAADDFRTKFETEQALRLSVEADINGLRRVLDELTLARADLEMQIENLKE 213

Query: 236 ELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEKNRRDVEA 295
           ELAYLKKNHEEEM     Q+ G++NVEMDAAPGVDL+R+L EMR+QYE MAEKNR+D E 
Sbjct: 214 ELAYLKKNHEEEMNALRGQVGGEINVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAED 273

Query: 296 WFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQSQLSMKAGLENSLAETEC 355
           WFFSKTEELN+EVA+N+E++Q+ K+EI++LRRTMQ LEIELQSQLSMKA LE +LAETE 
Sbjct: 274 WFFSKTEELNREVATNSELVQSGKSEISELRRTMQALEIELQSQLSMKASLEGNLAETEN 333

Query: 356 RYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTRLEQEIATYRSLLEGQDA 415
           RY  QL QIQGLIG +E QL++LRCEME QNQEYK+LLD+KTRLEQEIATYR LLEG+DA
Sbjct: 334 RYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDA 393

Query: 416 KMAGIGIREASSGGGGSSSNFHINVEESVDGQVVSSHKR 454
            +              ++      VEE  DG+V+SS ++
Sbjct: 394 HLTQYKKEPV------TTRQVRTIVEEVQDGKVISSREQ 426


>gi|24234699 keratin 19 [Homo sapiens]
          Length = 400

 Score =  496 bits (1276), Expect = e-140
 Identities = 262/415 (63%), Positives = 311/415 (74%), Gaps = 28/415 (6%)

Query: 1   MTTTFLQTSSSTFGGGSTRGGSLLAGGG-GFGGGSLSGGGGSRSISASSARFVSSGSGGG 59
           MT+   + SS+T   G   GGS+  G G  F   S+ GG G R +S SSARFVSS S G 
Sbjct: 1   MTSYSYRQSSATSSFGGLGGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGA 60

Query: 60  YGGGMRVCGFGGGAGSVFGGGFGGGVGGGFGGGFGGGDGGLLSGNEKITMQNLNDRLASY 119
           Y                         GGG+GG     D GLL+GNEK+TMQNLNDRLASY
Sbjct: 61  Y-------------------------GGGYGGVLTASD-GLLAGNEKLTMQNLNDRLASY 94

Query: 120 LDKVRALEEANADLEVKIHDWYQKQTPTSPECDYSQYFKTIEELRDKIMATTIDNSRVIL 179
           LDKVRALE AN +LEVKI DWYQKQ P  P  DYS Y+ TI++LRDKI+  TI+NSR++L
Sbjct: 95  LDKVRALEAANGELEVKIRDWYQKQGP-GPSRDYSHYYTTIQDLRDKILGATIENSRIVL 153

Query: 180 EIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNEELAY 239
           +IDNARLAADDFR K+E E ALR  VEADINGLRRVLDELTLARTDLEMQIEGL EELAY
Sbjct: 154 QIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAY 213

Query: 240 LKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEKNRRDVEAWFFS 299
           LKKNHEEE+     Q+ GQV+VE+D+APG DL ++L++MR QYE MAE+NR+D EAWF S
Sbjct: 214 LKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQNRKDAEAWFTS 273

Query: 300 KTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQSQLSMKAGLENSLAETECRYAT 359
           +TEELN+EVA +TE +Q S++E+TDLRRT+Q LEIELQSQLSMKA LE++LAETE R+  
Sbjct: 274 RTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQSQLSMKAALEDTLAETEARFGA 333

Query: 360 QLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTRLEQEIATYRSLLEGQD 414
           QL  IQ LI G+EAQL ++R + E QNQEY+ L+DIK+RLEQEIATYRSLLEGQ+
Sbjct: 334 QLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSRLEQEIATYRSLLEGQE 388


>gi|195972866 keratin 10 [Homo sapiens]
          Length = 584

 Score =  488 bits (1257), Expect = e-138
 Identities = 269/431 (62%), Positives = 315/431 (73%), Gaps = 14/431 (3%)

Query: 9   SSSTFGGGSTRGGSLLAGGGGFGGGSLSGGGGSRSISASSAR--FVSSGSGGGYGGGMRV 66
           SS  F GGS   GS    GGG  GGS  G GG       S R  + SS  GG YGG    
Sbjct: 48  SSGGFSGGSFSRGS---SGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGG 104

Query: 67  CGFGGGA---GSVFGGGFGGG-VGGGFGGGFGGGDGGLLSGNEKITMQNLNDRLASYLDK 122
             FGGG+   GS  GGGFGGG  GGGFGGGFGG DGGLLSGNEK+TMQNLNDRLASYLDK
Sbjct: 105 GSFGGGSFGGGSFGGGGFGGGGFGGGFGGGFGG-DGGLLSGNEKVTMQNLNDRLASYLDK 163

Query: 123 VRALEEANADLEVKIHDWYQKQ--TPTSPECDYSQYFKTIEELRDKIMATTIDNSRVILE 180
           VRALEE+N +LE KI +WY+K   +      DYS+Y+KTI++L+++I+  T DN+ ++L+
Sbjct: 164 VRALEESNYELEGKIKEWYEKHGNSHQGEPRDYSKYYKTIDDLKNQILNLTTDNANILLQ 223

Query: 181 IDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNEELAYL 240
           IDNARLAADDFRLKYENE+ALRQ VEADINGLRRVLDELTL + DLEMQIE L EELAYL
Sbjct: 224 IDNARLAADDFRLKYENEVALRQSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYL 283

Query: 241 KKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEKNRRDVEAWFFSK 300
           KKNHEEEMK+  +   G VNVEM+AAPGVDLT++L  MR QYE +AE+NR+D EAWF  K
Sbjct: 284 KKNHEEEMKDLRNVSTGDVNVEMNAAPGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEK 343

Query: 301 TEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQSQLSMKAGLENSLAETECRYATQ 360
           ++EL  E+ +N E I + K+EIT+LRR +Q LEIELQSQL++K  LE SLAETE RY  Q
Sbjct: 344 SKELTTEIDNNIEQISSYKSEITELRRNVQALEIELQSQLALKQSLEASLAETEGRYCVQ 403

Query: 361 LQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMAGI 420
           L QIQ  I  LE QL ++R E E QN EY+ LLDIK RLE EI TYRSLLEG+ +  +G 
Sbjct: 404 LSQIQAQISALEEQLQQIRAETECQNTEYQQLLDIKIRLENEIQTYRSLLEGEGS--SGG 461

Query: 421 GIREASSGGGG 431
           G R   S GGG
Sbjct: 462 GGRGGGSFGGG 472



 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 48/108 (44%), Positives = 51/108 (47%), Gaps = 15/108 (13%)

Query: 14  GGGSTRGGSLLAG-GGGFGGGSLSGGGGSRSISASSARFVSSG------SGGGYGGGMRV 66
           GGG   GGS   G GGG  GG  SGGG       SS      G      SGGGYGGG   
Sbjct: 460 GGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSS 519

Query: 67  CGFGGGAGSVFGGGFGGGVGGGFGGGFGGG--------DGGLLSGNEK 106
            G GG +   +GGG  GG GGG+GGG  GG         GG  SG  K
Sbjct: 520 GGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHK 567



 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 43/87 (49%), Positives = 48/87 (55%), Gaps = 11/87 (12%)

Query: 13  FGGGSTRGGSLLAGGGGFGGGSLSGGGGSRSISASSARFVSSGSGGGYGGGMRVCGFGGG 72
           +GGGS+ GGS   G GG  GGS  GG G  S    S       SGGGYGGG    G GG 
Sbjct: 473 YGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGS-------SGGGYGGGSSSGGHGGS 525

Query: 73  AGSVFGGGFGGGVGGGFGGGFGGGDGG 99
           +     GG+GGG  GG GGG+GGG  G
Sbjct: 526 SS----GGYGGGSSGGGGGGYGGGSSG 548



 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 28/50 (56%), Positives = 30/50 (60%), Gaps = 2/50 (4%)

Query: 54  SGSGGGYGGGMRVCGFGGGAGSVFGGGFGGGVGGGFGGGFGGGDGGLLSG 103
           S  GGG GGG    G+GGG+    GG  GGG GGG GG  GGG GG  SG
Sbjct: 458 SSGGGGRGGGSFGGGYGGGSSG--GGSSGGGHGGGHGGSSGGGYGGGSSG 505



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 27/52 (51%), Positives = 31/52 (59%), Gaps = 3/52 (5%)

Query: 46 ASSARFVSSGSGGGYGGGMRVCGFGGGAGSVFGGGFGGGVGGGFG-GGFGGG 96
          +SS  + SS SGGG GGG   CG GGG  S+      G +GGGF  GGF GG
Sbjct: 6  SSSKHYSSSRSGGGGGGGG--CGGGGGVSSLRISSSKGSLGGGFSSGGFSGG 55



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 25/51 (49%), Positives = 30/51 (58%)

Query: 8   TSSSTFGGGSTRGGSLLAGGGGFGGGSLSGGGGSRSISASSARFVSSGSGG 58
           +SS  +GGGS+ GG    GGG  GGGS SGGG     S+   +  SSGS G
Sbjct: 525 SSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVG 575



 Score = 35.8 bits (81), Expect = 0.083
 Identities = 23/47 (48%), Positives = 27/47 (57%), Gaps = 6/47 (12%)

Query: 10  SSTFGGGSTRGGSLLAG---GGGFGGGSLSGG---GGSRSISASSAR 50
           SS  GGG   GGS   G   GGG+GGGS SGG     S S+  SS++
Sbjct: 534 SSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSK 580


>gi|4557699 keratin 12 [Homo sapiens]
          Length = 494

 Score =  473 bits (1216), Expect = e-133
 Identities = 263/467 (56%), Positives = 331/467 (70%), Gaps = 30/467 (6%)

Query: 16  GSTRGGSLLAGGGGFGGGSL----SGGGGSRSISASSARFVSSGSGGGYGGGMRVCGFGG 71
           G  RG S  + G G+GG +     S GGG    SA+S    SSG GGG G  M   G G 
Sbjct: 28  GRPRGMSASSVGSGYGGSAFGFGASCGGG---FSAASMFGSSSGFGGGSGSSM-AGGLGA 83

Query: 72  GAGSVFGGGFGGGVGGGFGGGFGGG--------DGGLLSGNEKITMQNLNDRLASYLDKV 123
           G G   GGG  GG+G GFGG  GGG        DGGLLSG+EK TMQNLNDRLASYLDKV
Sbjct: 84  GYGRALGGGSFGGLGMGFGGSPGGGSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKV 143

Query: 124 RALEEANADLEVKIHDWYQKQ---TPTSPECDYSQYFKTIEELRDKIMATTIDNSRVILE 180
           RALEEAN +LE KI +WY+ +   T  + + DYS+Y+  IE+LR+KI++ +I N++++L+
Sbjct: 144 RALEEANTELENKIREWYETRGTGTADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQ 203

Query: 181 IDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNEELAYL 240
           IDNARLAA+DFR+KYENELALRQGVEADINGLRRVLDELTL RTDLEMQIE LNEELAY+
Sbjct: 204 IDNARLAAEDFRMKYENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYM 263

Query: 241 KKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEKNRRDVEAWFFSK 300
           KKNHE+E++ F     G+V+VEMDAAPGVDLTR+L +MR QYE +AE+NR+D EAWF  K
Sbjct: 264 KKNHEDELQSFRVGGPGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEK 323

Query: 301 TEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQSQLSMKAGLENSLAETECRYATQ 360
           + EL KE+++NTE +Q+SK+E+TDLRR  Q LEIELQSQL+MK  LE+SLAE E  Y  Q
Sbjct: 324 SGELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQ 383

Query: 361 LQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTRLEQEIATYRSLLEGQ---DAKM 417
           L Q+Q LI  LEAQL ++R + E QN +++ LL++K RLE EI TYR LL+G+   D   
Sbjct: 384 LSQVQQLISNLEAQLLQVRADAERQNVDHQRLLNVKARLELEIETYRRLLDGEAQGDGLE 443

Query: 418 AGIGIREASSGGGGSSSN--------FHINVEESVDGQVVSSHKREI 456
             + + ++ S    + S+            V+E V+G+VVSS  +EI
Sbjct: 444 ESLFVTDSKSQAQSTDSSKDPTKTRKIKTVVQEMVNGEVVSSQVQEI 490


>gi|192807292 keratin 24 [Homo sapiens]
          Length = 525

 Score =  439 bits (1128), Expect = e-123
 Identities = 257/497 (51%), Positives = 320/497 (64%), Gaps = 45/497 (9%)

Query: 3   TTFLQTSSSTFGGGST---RGG----SLLAGGGGFGGGSLSGGGGSRSISASSARFVSSG 55
           ++F   S    GG S    RGG    SL  G  G  GGS  GG GS S+        +SG
Sbjct: 25  SSFSSGSRCGLGGSSAQGFRGGASSCSLSGGSSGAFGGSFGGGFGSCSVGGGFGG--ASG 82

Query: 56  SGGGYGGGMR---VCGFGGGAGSVFGGGFGGGVGGGF---GGGFGGG--DGGLLSGNEKI 107
           SG G+GGG     V GFG G+G      F  G  GGF   GGG GGG  DGGL SG EK 
Sbjct: 83  SGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGATGGFYSYGGGMGGGVGDGGLFSGGEKQ 142

Query: 108 TMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPTSPEC----DYSQYFKTIEEL 163
           TMQNLNDRLA+YLDKVRALEEAN DLE KI +WY K  P S +     DYS+Y+  IE+L
Sbjct: 143 TMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDGGSGRDYSKYYSIIEDL 202

Query: 164 RDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTLAR 223
           R++I+A T++N+ +IL IDNARLAADDFRLKYENEL LRQ VEADINGLR+VLD+LT+ R
Sbjct: 203 RNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEADINGLRKVLDDLTMTR 262

Query: 224 TDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMREQYE 283
           +DLEMQIE   EELAYL+KNHEEEMK       G+V VEM+AAPG DLT++L +MR QYE
Sbjct: 263 SDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNAAPGTDLTKLLNDMRAQYE 322

Query: 284 AMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQSQLSMK 343
            +AE+NRR+ E  F  ++  L  +++++     ++K EIT+L+RT+Q LEIELQSQL+MK
Sbjct: 323 ELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITELKRTLQALEIELQSQLAMK 382

Query: 344 AGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTRLEQEI 403
           + LE +LA+TE  Y  QL +IQ  I  LE ++ ++  E + QN EYK LLDIKTRLE EI
Sbjct: 383 SSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNAEYKQLLDIKTRLEVEI 442

Query: 404 ATYRSLLEGQ------------DAKMAGIGIRE---------ASSGGGGSSSNFHIN--- 439
            TYR LL+G+            ++    +G R+         + SG G  SS   +    
Sbjct: 443 ETYRRLLDGEGGGSSFAEFGGRNSGSVNMGSRDLVSGDSRSGSCSGQGRDSSKTRVTKTI 502

Query: 440 VEESVDGQVVSSHKREI 456
           VEE VDG+VVSS    I
Sbjct: 503 VEELVDGKVVSSQVSSI 519


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score =  438 bits (1127), Expect = e-123
 Identities = 236/441 (53%), Positives = 305/441 (69%), Gaps = 22/441 (4%)

Query: 8   TSSSTFGGGSTR------GGSLL-----AGGGGFGGGSLSGG--GGSRSISASSARFVSS 54
           +SSS +GGGS+R      GGS         GGGF   SL GG  GGSR    +S    SS
Sbjct: 48  SSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSS 107

Query: 55  GSGGGYGGGMRVCGFGGGAGSVFGGGFGGGVGG--GFGGGFGGGDGGLLSGNEKITMQNL 112
              GG+GGG     FGGG+G  FGGG+G G GG  GFGGG GGGDGG+L+ NEK TMQ L
Sbjct: 108 S--GGFGGG-----FGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGGILTANEKSTMQEL 160

Query: 113 NDRLASYLDKVRALEEANADLEVKIHDWYQKQTPTSPECDYSQYFKTIEELRDKIMATTI 172
           N RLASYLDKV+ALEEAN DLE KI DWY K+ P + + +YS Y+ TI++L+D+I+  T+
Sbjct: 161 NSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQKNYSPYYNTIDDLKDQIVDLTV 220

Query: 173 DNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTLARTDLEMQIEG 232
            N++ +L+IDN R+  DDFR+K+E E  LRQGV+ADINGLR+VLD LT+ ++DLEMQ E 
Sbjct: 221 GNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDNLTMEKSDLEMQYET 280

Query: 233 LNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEKNRRD 292
           L EEL  LKKNH+EEM + + Q +G VNVE++ APG DLT+ L +MR++YE +  KNR+D
Sbjct: 281 LQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDMRQEYEQLIAKNRKD 340

Query: 293 VEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQSQLSMKAGLENSLAE 352
           +E  + ++  ++  EV+S+ + +Q+S  E+T LR  +QELEIELQSQLS KA LE SL +
Sbjct: 341 IENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSKKAALEKSLED 400

Query: 353 TECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTRLEQEIATYRSLLEG 412
           T+ RY  QLQ IQ  I  LEAQ++++R E+E QNQEY +LL IK RLE+EI TY +LLEG
Sbjct: 401 TKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMRLEKEIETYHNLLEG 460

Query: 413 QDAKMAGIGIREASSGGGGSS 433
                   G  +   GG G S
Sbjct: 461 GQEDFESSGAGKIGLGGRGGS 481



 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 47/95 (49%), Positives = 52/95 (54%), Gaps = 15/95 (15%)

Query: 9   SSSTFGGGSTRGGSLLAGGGGFGGGSLSGGGGSRSISASSARFVSSGSGGGYGGGMRVCG 68
           S  ++G GS RGGS  + GGG  GG   GG GSR            GSGG YGGG    G
Sbjct: 481 SGGSYGRGS-RGGSGGSYGGGGSGGGYGGGSGSR-----------GGSGGSYGGG---SG 525

Query: 69  FGGGAGSVFGGGFGGGVGGGFGGGFGGGDGGLLSG 103
            GGG+G  +GGG GGG  GG GGG  GG GG   G
Sbjct: 526 SGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGG 560



 Score = 79.3 bits (194), Expect = 7e-15
 Identities = 51/108 (47%), Positives = 58/108 (53%), Gaps = 14/108 (12%)

Query: 9   SSSTFGGGS-TRGGSLLAGGGGFGGGSLSGGGGSRSISASSARFVSSGSGGGYGGGM--- 64
           S   +GGGS +RGGS    GG +GGGS SGGG        S    S GSGGG+ GG    
Sbjct: 502 SGGGYGGGSGSRGGS----GGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGN 557

Query: 65  --RVCGFGGGAGSVFGGGFG--GGVGGGFGG--GFGGGDGGLLSGNEK 106
                G GGG+G  +GGG G  GG GG  GG  GFGG  GG   G E+
Sbjct: 558 YGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEE 605



 Score = 75.5 bits (184), Expect = 9e-14
 Identities = 46/103 (44%), Positives = 51/103 (49%), Gaps = 13/103 (12%)

Query: 9   SSSTFGGGSTRGGSLLAGGGGFGGGSLSGGGGSRSISASSARF-----VSSGSGGGYGGG 63
           S  ++GGGS  GG    G GG  GG  SGG G      S   +        GSGGGYGGG
Sbjct: 516 SGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGG 575

Query: 64  MRVCGFGGGA---GSVFGGGFGGGVGG-----GFGGGFGGGDG 98
               G  GG+   GS FGG  GG  GG     G GGG+GGG G
Sbjct: 576 SGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSG 618



 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 46/90 (51%), Positives = 50/90 (55%), Gaps = 20/90 (22%)

Query: 19  RGGSLLAGGGGFGGGSLSGGGGSRSISASSARFVSSGSGGGYGGGMRVCG-----FGGGA 73
           RGGS    GG +G GS  G GGS         +   GSGGGYGGG    G     +GGG+
Sbjct: 478 RGGS----GGSYGRGSRGGSGGS---------YGGGGSGGGYGGGSGSRGGSGGSYGGGS 524

Query: 74  GSVFGGGFGGGVGGGFGGGFGGGDGGLLSG 103
           GS  GGG GGG GGG GGG  GG GG  SG
Sbjct: 525 GS--GGGSGGGYGGGSGGGHSGGSGGGHSG 552



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 41/87 (47%), Positives = 45/87 (51%), Gaps = 3/87 (3%)

Query: 14  GGGSTRGGSLLAGGGGFGGGSLSGGGGSRSISASSARFVSSGSGGGYGGGMRVCGFGGGA 73
           G G + GG    GG G G GS  G GGS    + S      G GGG GGG    G GGG 
Sbjct: 492 GSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGG-HSGGSGGGH 550

Query: 74  GSVFGGGFGG--GVGGGFGGGFGGGDG 98
               GG +GG  G GGG GGG+GGG G
Sbjct: 551 SGGSGGNYGGGSGSGGGSGGGYGGGSG 577



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 46/102 (45%), Positives = 53/102 (51%), Gaps = 12/102 (11%)

Query: 6   LQTSSSTFGGGSTRGGSLLAGGGGFGGGSLSGGGGSRSISASSARFVSSGSGGGYGGGMR 65
           ++T  +   GG     S  AG  G GG   SGG        S  R    GSGG YGGG  
Sbjct: 451 IETYHNLLEGGQEDFESSGAGKIGLGGRGGSGG--------SYGRGSRGGSGGSYGGGGS 502

Query: 66  VCGFGGGAGS--VFGGGFGG--GVGGGFGGGFGGGDGGLLSG 103
             G+GGG+GS    GG +GG  G GGG GGG+GGG GG  SG
Sbjct: 503 GGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSG 544



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 25/55 (45%), Positives = 30/55 (54%), Gaps = 8/55 (14%)

Query: 51  FVSSGSGG-GYGGGMRVCGFGGGAGSVFGGGFGGGVGGGFGGGFGGGDGGLLSGN 104
           F SSG+G  G GG        GG+G  +G G  GG GG +GGG  GG  G  SG+
Sbjct: 465 FESSGAGKIGLGGR-------GGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGS 512


>gi|114431246 keratin 25D [Homo sapiens]
          Length = 464

 Score =  415 bits (1067), Expect = e-116
 Identities = 226/406 (55%), Positives = 280/406 (68%), Gaps = 12/406 (2%)

Query: 36  SGGGGSRSISASSARFVSSGSGGGYGGGMRVCGFGGGAGSVFGGGFGGG-VGGGFGGGFG 94
           SG G  R ++  +    SS  GG   G    C  GGG GSV GG   GG +G     GF 
Sbjct: 16  SGAGSVRPLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGALGNAACIGFA 75

Query: 95  GGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPTSP---EC 151
           G +GGLLSGNEK+TMQNLNDRLASYLD VRALEEANA+LE KI  WY+K  P S    + 
Sbjct: 76  GSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDH 135

Query: 152 DYSQYFKTIEELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADING 211
           DYS+Y  TIE+L++KI+++T  N+ VIL+IDNARLAADDFRLKYENEL L Q VEADING
Sbjct: 136 DYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADING 195

Query: 212 LRRVLDELTLARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDL 271
           LRRVLDELTL RTD E+Q E L+EE+ YLKKNHEEEMK       G VNVEM+AAPGVDL
Sbjct: 196 LRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDL 255

Query: 272 TRVLAEMREQYEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQE 331
             +L  MR +YEA+AE+NR+D EAWF  K+  L ++++ ++     +++++T++RRT+Q 
Sbjct: 256 AVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQT 315

Query: 332 LEIELQSQLSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKM 391
           LEI+LQS ++ K  LE SL ETE  Y TQL QIQ  IG LE QL ++R E E Q  EY+ 
Sbjct: 316 LEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEH 375

Query: 392 LLDIKTRLEQEIATYRSLLEGQD---AKMAGIGIREASSGGGGSSS 434
           LLD+K  LE+EI TY  L++G     +K  G G     SG  G+SS
Sbjct: 376 LLDVKVHLEKEIETYCRLIDGDGNSCSKSKGFG-----SGSPGNSS 416


>gi|153945736 keratin 27 [Homo sapiens]
          Length = 459

 Score =  413 bits (1061), Expect = e-115
 Identities = 241/464 (51%), Positives = 296/464 (63%), Gaps = 40/464 (8%)

Query: 1   MTTTFLQTSSSTFGGGSTRGGSLLAGGGGFGGGSLSGGGGSRSISASSARFVSSGSGGGY 60
           M+  F  TS      G T    L +GG GFG G+  G  G  S    S  F  S S GGY
Sbjct: 1   MSVRFSSTSRRLGSCGGTGSVRLSSGGAGFGAGNTCGVPGIGS--GFSCAFGGSSSAGGY 58

Query: 61  GGGMRVCGFGGGAGSVFGGGFGGGVGGGFGGGFGGGDGGLLSGNEKITMQNLNDRLASYL 120
           GGG+     GGG+ S                 F G + GLLSGNEK+TMQNLNDRLASYL
Sbjct: 59  GGGL-----GGGSASC--------------AAFTGNEHGLLSGNEKVTMQNLNDRLASYL 99

Query: 121 DKVRALEEANADLEVKIHDWYQKQTPTS---PECDYSQYFKTIEELRDKIMATTIDNSRV 177
           + VRALEEANADLE KI  WY+K  P S    + DYS+YF  I+EL+++I++ T  N+ V
Sbjct: 100 ENVRALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHV 159

Query: 178 ILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNEEL 237
           +L+ DNARL ADDFRLK+ENELAL Q VEADINGLRRVLDELTL RTDLE+Q+E L+EEL
Sbjct: 160 VLQNDNARLTADDFRLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEEL 219

Query: 238 AYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEKNRRDVEAWF 297
           AYLKKNHEEEMK       G VNVEM+AAPGVDLT +L  MR +YEA+AE+NRRD EAWF
Sbjct: 220 AYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWF 279

Query: 298 FSKTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQSQLSMKAGLENSLAETECRY 357
             K+  L ++++ +     +++ E+ +++RT+Q LEIELQS L+ K  LE SL ETE  Y
Sbjct: 280 NEKSASLQQQISDDAGATTSARNELIEMKRTLQTLEIELQSLLATKHSLECSLTETESNY 339

Query: 358 ATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKM 417
             QL QIQ  IG LE QL ++R E E Q  EY+ LLDIK  LE+EI TY  L++G+D   
Sbjct: 340 CAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKVHLEKEIETYCLLIDGED--- 396

Query: 418 AGIGIREASSGGGG--------SSSNFHINVEESVD--GQVVSS 451
              G    S G GG        S +     V E +D  G+V+SS
Sbjct: 397 ---GSCSKSKGYGGPGNQTKDSSKTTIVKTVVEEIDPRGKVLSS 437


>gi|31559829 keratin 25 [Homo sapiens]
          Length = 450

 Score =  401 bits (1031), Expect = e-112
 Identities = 216/395 (54%), Positives = 268/395 (67%), Gaps = 7/395 (1%)

Query: 45  SASSARFVSSGSGGGYGGGMRVCGFGGGAGSVFGGGFGGGVGGGFG--GGFGGGDGGLLS 102
           +  S R    G+  G G    + G G G  S FGG   GG  GG     GF   + GLLS
Sbjct: 17  TTGSLRLYGGGTSFGTGNSCGISGIGSGFSSAFGGSSSGGNTGGGNPCAGFTVNERGLLS 76

Query: 103 GNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPTSP---ECDYSQYFKT 159
           GNEK+TMQNLNDRLASYLD V ALEEANADLE KI  WY+K  P S    + DYS+YF  
Sbjct: 77  GNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYFPI 136

Query: 160 IEELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDEL 219
           I++L+++I+A+T  N+  +L+IDNARL ADDFRLKYENELAL Q VEAD+NGLRRVLDE+
Sbjct: 137 IDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRRVLDEI 196

Query: 220 TLARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMR 279
           TL RTDLE+Q E L+EE+ YLKKNH+EEM+       G VNVEM+AAPGVDLT +L  MR
Sbjct: 197 TLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTVLLNNMR 256

Query: 280 EQYEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQSQ 339
            +YEA+AE+NRRD EAWF  K+  L ++++ +     +++ E+T+++RT+Q LEIELQS 
Sbjct: 257 AEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLEIELQSL 316

Query: 340 LSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTRL 399
           L+ K  LE SL ETE  Y  QL QIQ  IG LE QL ++R E E Q  EY+ LLDIK  L
Sbjct: 317 LATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKLHL 376

Query: 400 EQEIATYRSLLEGQD--AKMAGIGIREASSGGGGS 432
           E+EI TY  L+ G D   K  G   ++  SG  GS
Sbjct: 377 EKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGS 411


>gi|4504927 keratin 36 [Homo sapiens]
          Length = 467

 Score =  400 bits (1029), Expect = e-111
 Identities = 225/413 (54%), Positives = 285/413 (69%), Gaps = 14/413 (3%)

Query: 7   QTSSSTFGGGSTRGGSLLAGGGGFGGGSLSGGGGSRSISASSARFVSSGSGGGYGGGMRV 66
           QT + TF  GS +G    AGG       +S     RS+   S R  S     GY    R 
Sbjct: 4   QTCTPTFSTGSIKGLCGTAGG-------ISRVSSIRSVG--SCRVPSLAGAAGYISSAR- 53

Query: 67  CGFGGGAGSVFGGGFGGGV--GGGFGGGFGGGDGGLLSGNEKITMQNLNDRLASYLDKVR 124
            G  G  GS   G +        GF G  G    G  +G+EK TMQ LNDRLA+YL+KVR
Sbjct: 54  SGLSG-LGSCLPGSYLSSECHTSGFVGSGGWFCEGSFNGSEKETMQFLNDRLANYLEKVR 112

Query: 125 ALEEANADLEVKIHDWYQKQTPTSPECDYSQYFKTIEELRDKIMATTIDNSRVILEIDNA 184
            LE  NA+LE +I +WY+ Q P     DY  YFKTIE+ + KI+ T  +N+R++L+IDNA
Sbjct: 113 QLERENAELESRIQEWYEFQIPYICP-DYQSYFKTIEDFQQKILLTKSENARLVLQIDNA 171

Query: 185 RLAADDFRLKYENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNEELAYLKKNH 244
           +LAADDFR KYE EL+LRQ VEADINGLRR+LDELTL + DLE Q+E L EEL  LKKNH
Sbjct: 172 KLAADDFRTKYETELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNH 231

Query: 245 EEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEKNRRDVEAWFFSKTEEL 304
           EEE+     QL  ++NVE+DAAP VDL ++L +MR QYEA+ E NRRDVEAWF ++TEEL
Sbjct: 232 EEEVSVLRCQLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEEL 291

Query: 305 NKEVASNTEMIQTSKTEITDLRRTMQELEIELQSQLSMKAGLENSLAETECRYATQLQQI 364
           N++V S++E +Q  +TEI +LRRT+  LEIELQ+Q SM+  LE++LAETE RY++QL Q+
Sbjct: 292 NQQVVSSSEQLQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQM 351

Query: 365 QGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKM 417
           Q LI  +EAQLSE+RC++E QNQEY++LLD+K RLE EIATYR LLEG+D K+
Sbjct: 352 QCLISNVEAQLSEIRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGEDCKL 404


>gi|94538345 keratin 35 [Homo sapiens]
          Length = 455

 Score =  384 bits (987), Expect = e-107
 Identities = 212/405 (52%), Positives = 279/405 (68%), Gaps = 21/405 (5%)

Query: 29  GFGGGSL-SGGGGSRSISASSARFVSSG----SGGGYGGGMRVCGFGGGAGS-------- 75
           GF  GSL S GG S   +  SA + SS     S          C  G G  S        
Sbjct: 9   GFSSGSLKSPGGASGGSTRVSAMYSSSSCKLPSLSPVARSFSACSVGLGRSSYRATSCLP 68

Query: 76  ---VFGGGFGGGVGGGFGGGFGGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANAD 132
              +  GGF     GG GG FG G   +L+GNEK TMQ+LNDRLA YL+KVR LE+ NA 
Sbjct: 69  ALCLPAGGFATSYSGG-GGWFGEG---ILTGNEKETMQSLNDRLAGYLEKVRQLEQENAS 124

Query: 133 LEVKIHDWYQKQTPTSPECDYSQYFKTIEELRDKIMATTIDNSRVILEIDNARLAADDFR 192
           LE +I +W ++Q P     DY  YF+TIEEL+ K + +  +N+R+++EIDNA+LAADDFR
Sbjct: 125 LESRIREWCEQQVPYMCP-DYQSYFRTIEELQKKTLCSKAENARLVVEIDNAKLAADDFR 183

Query: 193 LKYENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNEELAYLKKNHEEEMKEFS 252
            KYE E++LRQ VE+DINGLRR+LD+LTL ++DLE Q+E L EEL  LKKNHEEE+    
Sbjct: 184 TKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNHEEEVNSLR 243

Query: 253 SQLAGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEKNRRDVEAWFFSKTEELNKEVASNT 312
            QL  ++NVE+DAAP VDL RVL EMR QYE + E NRRD E W  +++EELN++V S++
Sbjct: 244 CQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEELNQQVVSSS 303

Query: 313 EMIQTSKTEITDLRRTMQELEIELQSQLSMKAGLENSLAETECRYATQLQQIQGLIGGLE 372
           E +Q+ + EI +LRRT+  LEIELQ+Q SM+  LE++LAETE RY++QL Q+Q +I  +E
Sbjct: 304 EQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQMQCMITNVE 363

Query: 373 AQLSELRCEMEAQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKM 417
           AQL+E+R ++E QNQEY++LLD++ RLE EI TYR LLE +D+K+
Sbjct: 364 AQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESEDSKL 408


>gi|31559815 keratin 26 [Homo sapiens]
          Length = 468

 Score =  376 bits (966), Expect = e-104
 Identities = 218/427 (51%), Positives = 275/427 (64%), Gaps = 22/427 (5%)

Query: 39  GGSRSISASSARFVSSGSGGGYGGGMRVCGFGGGAGSVF---------GGGF---GGGVG 86
           GGSR I + +     SG G G+  G  VC  G GA S F         GG F   GGG+G
Sbjct: 7   GGSRRICSRTGSGRLSGGGTGFVAG-NVC-VGSGARSSFSCTLEGISSGGSFCNSGGGLG 64

Query: 87  GGFGGGFGGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTP 146
            G   GF G +  LLSGNEK+TMQNLNDRLASYLD V ALEEANADLE KI   Y+K  P
Sbjct: 65  SGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRYEKCEP 124

Query: 147 TSP---ECDYSQYFKTIEELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQ 203
            S    + DYS+YF  IE+L+ +I + TI N+ ++L+ DNARL ADDFRLKYENELAL  
Sbjct: 125 GSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENELALHH 184

Query: 204 GVEADINGLRRVLDELTLARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEM 263
            VEAD +GLRRVLDELTL  TDLE+Q E L+EEL YLKK+HEEEM+       G VNVEM
Sbjct: 185 SVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNVNVEM 244

Query: 264 DAAPGVDLTRVLAEMREQYEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEIT 323
           +A PGVDLT +L  MR +YE +AE+NR+D EAWF  ++  L ++++ +      ++ E+T
Sbjct: 245 NATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAARNELT 304

Query: 324 DLRRTMQELEIELQSQLSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEME 383
           +L+R +Q LEIELQS +++K   E SLAETE  Y  QLQQIQ  IG +E QL ++R E E
Sbjct: 305 ELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRTETE 364

Query: 384 AQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMAGI-----GIREASSGGGGSSSNFHI 438
            Q  EY+ LLD+K  LE+EI  Y +LL+G++ K         G R  +SG     S    
Sbjct: 365 GQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERKSKSTCYKSKGYRPVNSGNQAKDSTEET 424

Query: 439 NVEESVD 445
            V+  V+
Sbjct: 425 IVKTVVE 431


>gi|116488398 keratin 32 [Homo sapiens]
          Length = 448

 Score =  370 bits (949), Expect = e-102
 Identities = 192/334 (57%), Positives = 251/334 (75%), Gaps = 2/334 (0%)

Query: 84  GVGGGFGGGFGGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQK 143
           G+ G  G G    +G   +GNEK TMQ LNDRLASYL +VR LE+ NA+LE +I +    
Sbjct: 76  GISGSMGPGSWYSEGAF-NGNEKETMQFLNDRLASYLTRVRQLEQENAELESRIQEASHS 134

Query: 144 QTPTSPECDYSQYFKTIEELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQ 203
           Q  T    DY  +F+TIEEL+ KI+ T  +N+R+++ IDNA+LAADDFR KYE ELA+RQ
Sbjct: 135 QVLTMTP-DYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDFRAKYEAELAMRQ 193

Query: 204 GVEADINGLRRVLDELTLARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEM 263
            VEADINGLRR+LD+LTL + DLE Q+E L EEL  LKKNHEEE+     QL  ++N+E+
Sbjct: 194 LVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQLGDRLNIEV 253

Query: 264 DAAPGVDLTRVLAEMREQYEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEIT 323
           DAAP VDLTRVL EMR QYEAM E NRRDVE WF  + EELN++VA+++E +Q  +++I 
Sbjct: 254 DAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQLQNYQSDII 313

Query: 324 DLRRTMQELEIELQSQLSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEME 383
           DLRRT+  LEIELQ+Q S++  LEN+L E+E RY++QL Q+Q +I  +EAQL+E+R ++E
Sbjct: 314 DLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEIRADLE 373

Query: 384 AQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKM 417
            QNQEY++LLD++ RLE EI TYRSLLE +D K+
Sbjct: 374 RQNQEYQVLLDVRARLEGEINTYRSLLENEDCKL 407


>gi|27894337 keratin 20 [Homo sapiens]
          Length = 424

 Score =  367 bits (942), Expect = e-101
 Identities = 197/393 (50%), Positives = 265/393 (67%), Gaps = 9/393 (2%)

Query: 71  GGAGSVFGGGFGGGVG-------GGFGGGFGGGDGGLLSGNEKITMQNLNDRLASYLDKV 123
           G   SV+GG  G G+          +G    GG G L  GNEK+ MQNLNDRLASYL+KV
Sbjct: 30  GTTPSVYGGAGGRGIRISNSRHTVNYGSDLTGG-GDLFVGNEKMAMQNLNDRLASYLEKV 88

Query: 124 RALEEANADLEVKIHDWYQKQTPTSPECDYSQYFKTIEELRDKIMATTIDNSRVILEIDN 183
           R LE++N+ LEV+I  WY+   P +   DYS Y++ IEELR +I    + N+R +L+IDN
Sbjct: 89  RTLEQSNSKLEVQIKQWYETNAPRAGR-DYSAYYRQIEELRSQIKDAQLQNARCVLQIDN 147

Query: 184 ARLAADDFRLKYENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNEELAYLKKN 243
           A+LAA+DFRLKYE E  +R  VEAD+ GL +V D+LTL +TDLE+QIE LN++LA LKK 
Sbjct: 148 AKLAAEDFRLKYETERGIRLTVEADLQGLNKVFDDLTLHKTDLEIQIEELNKDLALLKKE 207

Query: 244 HEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEKNRRDVEAWFFSKTEE 303
           H+EE+      L   VNVE+DAAPG++L  ++ EMR++YE MA+KN ++ +  F  +T  
Sbjct: 208 HQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFERQTAV 267

Query: 304 LNKEVASNTEMIQTSKTEITDLRRTMQELEIELQSQLSMKAGLENSLAETECRYATQLQQ 363
           L ++V  NTE ++ ++ ++T+LRRT Q LEIELQS LSMK  LE++L ET+ RY++QL  
Sbjct: 268 LQQQVTVNTEELKGTEVQLTELRRTSQSLEIELQSHLSMKESLEHTLEETKARYSSQLAN 327

Query: 364 IQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMAGIGIR 423
           +Q L+  LEAQL ++R  ME QN EY +LLDIKTRLEQEIATYR LLEG+D K     + 
Sbjct: 328 LQSLLSSLEAQLMQIRSNMERQNNEYHILLDIKTRLEQEIATYRRLLEGEDVKTTEYQLS 387

Query: 424 EASSGGGGSSSNFHINVEESVDGQVVSSHKREI 456
                    +      V+E VDG+VVSS  +E+
Sbjct: 388 TLEERDIKKTRKIKTVVQEVVDGKVVSSEVKEV 420


>gi|14917117 keratin 33A [Homo sapiens]
          Length = 404

 Score =  360 bits (925), Expect = 1e-99
 Identities = 184/319 (57%), Positives = 246/319 (77%), Gaps = 1/319 (0%)

Query: 99  GLLSGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPTSPECDYSQYFK 158
           G  +G+EK TMQ LNDRLASYL+KVR LE  NA+LE  I +  Q+Q P      Y  YFK
Sbjct: 50  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVC-ASYQSYFK 108

Query: 159 TIEELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDE 218
           TIEEL+ KI+ +  +N+R++++IDNA+LA+DDFR KYE EL+LRQ VE+DINGLRR+LDE
Sbjct: 109 TIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDE 168

Query: 219 LTLARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEM 278
           LTL R+DLE Q+E L EEL  LK+NHE+E+     QL  ++NVE+DAAP VDL +VL E 
Sbjct: 169 LTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNET 228

Query: 279 REQYEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQS 338
           R QYEA+ E NRR+VE WF ++TEELNK+V S++E +Q+ + EI +LRRT+  LEIELQ+
Sbjct: 229 RSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQA 288

Query: 339 QLSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTR 398
           Q +++  LEN+L E+E RY++QL Q+Q LI  +E+QL+E+R ++E QNQEY++LLD++ R
Sbjct: 289 QHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRAR 348

Query: 399 LEQEIATYRSLLEGQDAKM 417
           LE EI TYRSLLE +D K+
Sbjct: 349 LECEINTYRSLLESEDCKL 367


>gi|14917115 keratin 31 [Homo sapiens]
          Length = 416

 Score =  360 bits (925), Expect = 1e-99
 Identities = 184/319 (57%), Positives = 244/319 (76%), Gaps = 1/319 (0%)

Query: 99  GLLSGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPTSPECDYSQYFK 158
           G  +G+EK TMQ LNDRLASYL+KVR LE  NA+LE  I +  Q+Q P      Y  YFK
Sbjct: 50  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCP-SYQSYFK 108

Query: 159 TIEELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDE 218
           TIEEL+ KI+ T  +N+R++++IDNA+LAADDFR KY+ EL+LRQ VE+DINGLRR+LDE
Sbjct: 109 TIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDE 168

Query: 219 LTLARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEM 278
           LTL ++DLE Q+E L EEL  LK NHE+E+     QL  ++NVE+DAAP VDL RVL E 
Sbjct: 169 LTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNET 228

Query: 279 REQYEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQS 338
           R QYEA+ E NRR+VE WF ++TEELNK+V S++E +Q+ + EI +LRRT+  LEIELQ+
Sbjct: 229 RSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQA 288

Query: 339 QLSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTR 398
           Q +++  LEN+L E+E RY++QL Q+Q LI  +E+QL+E+R ++E QNQEY++LLD++ R
Sbjct: 289 QHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRAR 348

Query: 399 LEQEIATYRSLLEGQDAKM 417
           LE EI TYRSLLE +D  +
Sbjct: 349 LECEINTYRSLLESEDCNL 367


>gi|10337581 type I hair keratin 3B [Homo sapiens]
          Length = 404

 Score =  356 bits (914), Expect = 2e-98
 Identities = 182/319 (57%), Positives = 244/319 (76%), Gaps = 1/319 (0%)

Query: 99  GLLSGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPTSPECDYSQYFK 158
           G  +G+EK TMQ LNDRLASYL+KVR LE  NA+LE  I +  Q+Q P      Y  YFK
Sbjct: 50  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCP-SYQSYFK 108

Query: 159 TIEELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDE 218
           TIEEL+ KI+ +  +N+R++++IDNA+LAADDFR KY+ E +LRQ VE+DIN LRR+LDE
Sbjct: 109 TIEELQQKILCSKSENARLVVQIDNAKLAADDFRTKYQTEQSLRQLVESDINSLRRILDE 168

Query: 219 LTLARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEM 278
           LTL R+DLE Q+E L EEL  LK+NHE+E+     QL  ++NVE+DAAP VDL +VL E 
Sbjct: 169 LTLCRSDLEAQMESLKEELLSLKQNHEQEVNTLRCQLGDRLNVEVDAAPAVDLNQVLNET 228

Query: 279 REQYEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQS 338
           R QYEA+ E NRR+VE WF ++TEELNK+V S++E +Q+ + EI +LRRT+  LEIELQ+
Sbjct: 229 RNQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQA 288

Query: 339 QLSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTR 398
           Q +++  LEN+L E+E RY++QL Q+Q LI  +E+QL+E+R ++E QNQEY++LLD++ R
Sbjct: 289 QHNLRYSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRAR 348

Query: 399 LEQEIATYRSLLEGQDAKM 417
           LE EI TYRSLLE +D K+
Sbjct: 349 LECEINTYRSLLESEDCKL 367


>gi|14917119 keratin 34 [Homo sapiens]
          Length = 436

 Score =  354 bits (909), Expect = 8e-98
 Identities = 180/319 (56%), Positives = 241/319 (75%), Gaps = 1/319 (0%)

Query: 99  GLLSGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPTSPECDYSQYFK 158
           G  +G+EK TMQ LNDRLASYL+KVR LE  NA+LE  I +  Q+Q P      Y  YFK
Sbjct: 92  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELEKLIQERSQQQEPLLCP-SYQSYFK 150

Query: 159 TIEELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDE 218
           TIEEL+ KI+    +N+R+++ IDNA+LA+DDFR KY+ E +LR  VE+DIN +RR+LDE
Sbjct: 151 TIEELQQKILCAKAENARLVVNIDNAKLASDDFRSKYQTEQSLRLLVESDINSIRRILDE 210

Query: 219 LTLARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEM 278
           LTL ++DLE Q+E L EEL  LKKNHEEE+    SQL  ++NVE+D AP VDL +VL E 
Sbjct: 211 LTLCKSDLESQVESLREELICLKKNHEEEVNTLRSQLGDRLNVEVDTAPTVDLNQVLNET 270

Query: 279 REQYEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQS 338
           R QYEA+ E NRR+VE WF ++TEELNK+V S++E +Q+ + EI +LRRT+  LEIELQ+
Sbjct: 271 RSQYEALVEINRREVEQWFATQTEELNKQVVSSSEQLQSCQAEIIELRRTVNALEIELQA 330

Query: 339 QLSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTR 398
           Q +++  LEN+L E+E  Y++QL Q+Q LI  +E+QL+E+RC++E QNQEY++LLD++ R
Sbjct: 331 QHNLRDSLENTLTESEAHYSSQLSQVQSLITNVESQLAEIRCDLERQNQEYQVLLDVRAR 390

Query: 399 LEQEIATYRSLLEGQDAKM 417
           LE EI TYRSLLE +D K+
Sbjct: 391 LECEINTYRSLLESEDCKL 409


>gi|40354195 keratin 18 [Homo sapiens]
          Length = 430

 Score =  335 bits (860), Expect = 4e-92
 Identities = 187/413 (45%), Positives = 268/413 (64%), Gaps = 19/413 (4%)

Query: 40  GSRSISASSARFVSSGSGGGYGGGMRVCGFGGGAGSVFGGGFGGGVGGGFGGGFGGGDGG 99
           G+R +S++++ +  +G  G      R   F GG GS   GG   G+ GG  G      GG
Sbjct: 25  GARPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGS---GGLATGIAGGLAGM-----GG 76

Query: 100 LLSGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPTSPECDYSQYFKT 159
           +   NEK TMQ+LNDRLASYLD+VR+LE  N  LE KI +  +K+ P     D+S YFK 
Sbjct: 77  IQ--NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQVR--DWSHYFKI 132

Query: 160 IEELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDEL 219
           IE+LR +I A T+DN+R++L+IDNARLAADDFR+KYE ELA+RQ VE DI+GLR+V+D+ 
Sbjct: 133 IEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDT 192

Query: 220 TLARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQ-VNVEMDAAPGVDLTRVLAEM 278
            + R  LE +IE L EEL ++KKNHEEE+K   +Q+A   + VE+DA    DL +++A++
Sbjct: 193 NITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADI 252

Query: 279 REQYEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQS 338
           R QY+ +A KNR +++ ++  + EE    V + +  +  ++T +T+LRRT+Q LEI+L S
Sbjct: 253 RAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDS 312

Query: 339 QLSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTR 398
             ++KA LENSL E E RYA Q++Q+ G++  LE++L++ R E + Q QEY+ LL+IK +
Sbjct: 313 MRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVK 372

Query: 399 LEQEIATYRSLLE-GQDAKMAGIGIREASSGGGGSSSNFHINVEESVDGQVVS 450
           LE EIATYR LLE G+D       + +A        +         VDG+VVS
Sbjct: 373 LEAEIATYRRLLEDGED-----FNLGDALDSSNSMQTIQKTTTRRIVDGKVVS 420


>gi|4557888 keratin 18 [Homo sapiens]
          Length = 430

 Score =  335 bits (860), Expect = 4e-92
 Identities = 187/413 (45%), Positives = 268/413 (64%), Gaps = 19/413 (4%)

Query: 40  GSRSISASSARFVSSGSGGGYGGGMRVCGFGGGAGSVFGGGFGGGVGGGFGGGFGGGDGG 99
           G+R +S++++ +  +G  G      R   F GG GS   GG   G+ GG  G      GG
Sbjct: 25  GARPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGS---GGLATGIAGGLAGM-----GG 76

Query: 100 LLSGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPTSPECDYSQYFKT 159
           +   NEK TMQ+LNDRLASYLD+VR+LE  N  LE KI +  +K+ P     D+S YFK 
Sbjct: 77  IQ--NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQVR--DWSHYFKI 132

Query: 160 IEELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDEL 219
           IE+LR +I A T+DN+R++L+IDNARLAADDFR+KYE ELA+RQ VE DI+GLR+V+D+ 
Sbjct: 133 IEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDT 192

Query: 220 TLARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQ-VNVEMDAAPGVDLTRVLAEM 278
            + R  LE +IE L EEL ++KKNHEEE+K   +Q+A   + VE+DA    DL +++A++
Sbjct: 193 NITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADI 252

Query: 279 REQYEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQS 338
           R QY+ +A KNR +++ ++  + EE    V + +  +  ++T +T+LRRT+Q LEI+L S
Sbjct: 253 RAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDS 312

Query: 339 QLSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTR 398
             ++KA LENSL E E RYA Q++Q+ G++  LE++L++ R E + Q QEY+ LL+IK +
Sbjct: 313 MRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVK 372

Query: 399 LEQEIATYRSLLE-GQDAKMAGIGIREASSGGGGSSSNFHINVEESVDGQVVS 450
           LE EIATYR LLE G+D       + +A        +         VDG+VVS
Sbjct: 373 LEAEIATYRRLLEDGED-----FNLGDALDSSNSMQTIQKTTTRRIVDGKVVS 420


>gi|125490370 type I hair keratin KA36 [Homo sapiens]
          Length = 431

 Score =  323 bits (829), Expect = 2e-88
 Identities = 166/322 (51%), Positives = 233/322 (72%), Gaps = 1/322 (0%)

Query: 97  DGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPTSPECDYSQY 156
           + G+ + NEK TMQ LNDRLASYL+KVR+LEE NA+LE +I +  ++  P     DY +Y
Sbjct: 81  EDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPMVCP-DYQRY 139

Query: 157 FKTIEELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVL 216
           F TIE+L+ KI+ T  +NSR+ +++DN +LA DDF+ KYE+EL+LRQ +EADI+ L  +L
Sbjct: 140 FNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLHGIL 199

Query: 217 DELTLARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLA 276
           +ELTL ++DLE  +E L E+L  LKKNHEEE+     QL  +++VE+D AP +DL RVL 
Sbjct: 200 EELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDLNRVLD 259

Query: 277 EMREQYEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIEL 336
           EMR Q E +   NRR+ E W   +TEELN++  S+ E +Q  + EI +L+RT   LEIEL
Sbjct: 260 EMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASALEIEL 319

Query: 337 QSQLSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIK 396
           Q+Q S+   LE ++AETE +Y++QL QIQ LI  LE QL+E+RC++E QNQEY++LLD+K
Sbjct: 320 QAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVLLDVK 379

Query: 397 TRLEQEIATYRSLLEGQDAKMA 418
            RLE EI TY  LL+ +D++++
Sbjct: 380 ARLEGEINTYWGLLDSEDSRLS 401


>gi|148277620 type I hair keratin KA35 [Homo sapiens]
          Length = 491

 Score =  320 bits (820), Expect = 2e-87
 Identities = 168/321 (52%), Positives = 226/321 (70%), Gaps = 3/321 (0%)

Query: 96  GDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPTSPECDYSQ 155
           G+G  ++ NEK TMQ LN+RLA+YL KVR LE  NA+LE KI +   K+ P     DY  
Sbjct: 89  GEG--INSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCP-DYLS 145

Query: 156 YFKTIEELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRV 215
           Y+ TIEEL+ KI+ T  +NSR++ +IDN +L ADD R KYE E++LRQ VE+D NGL+++
Sbjct: 146 YYTTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQI 205

Query: 216 LDELTLARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVL 275
           L+ LTL + DLE Q++ L EEL  LK NH+EE+     QL  ++++E+ AAP  DL +VL
Sbjct: 206 LNVLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVL 265

Query: 276 AEMREQYEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIE 335
            EMR QYE + E NR+DVE WF ++ EELN++V ++++  Q  + EI +LRR++  LE+E
Sbjct: 266 QEMRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVE 325

Query: 336 LQSQLSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDI 395
           LQ+Q  M+   E  L ETE RY   L QIQ LI  LEAQL+E+RC +E QNQEY++LLD+
Sbjct: 326 LQAQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDV 385

Query: 396 KTRLEQEIATYRSLLEGQDAK 416
           K+RLE EI TYRSLLE  D K
Sbjct: 386 KSRLECEITTYRSLLESSDGK 406


>gi|15431318 keratin 38 [Homo sapiens]
          Length = 456

 Score =  319 bits (818), Expect = 3e-87
 Identities = 171/331 (51%), Positives = 237/331 (71%), Gaps = 6/331 (1%)

Query: 88  GFGGGFGGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPT 147
           G  G +G      L+G+EK TMQ LNDRLA+YL+KVR LE+ NA+LE  + +  + +   
Sbjct: 90  GICGAYGENT---LNGHEKETMQFLNDRLANYLEKVRQLEQENAELEATLLE--RSKCHE 144

Query: 148 SPEC-DYSQYFKTIEELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVE 206
           S  C DY  YF TIEEL+ KI+ +  +N+R+I++IDNA+LAADDFR+K E+E +LRQ VE
Sbjct: 145 STVCPDYQSYFHTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLRQLVE 204

Query: 207 ADINGLRRVLDELTLARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAA 266
           AD  G +++LD+ TLA+ DLE Q E L EE   LK NHE+E+K   SQL  ++ +E+D  
Sbjct: 205 ADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKLRIELDIE 264

Query: 267 PGVDLTRVLAEMREQYEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLR 326
           P +DL RVL EMR QYEAM E NR+DVE WF +++E ++ +  S +E +Q  ++EI +LR
Sbjct: 265 PTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSEILELR 324

Query: 327 RTMQELEIELQSQLSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQN 386
            T+  LE+E Q+Q ++K  L+NSL E E R+ T+L Q+Q LI  +E QLSE+R ++E QN
Sbjct: 325 CTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLERQN 384

Query: 387 QEYKMLLDIKTRLEQEIATYRSLLEGQDAKM 417
           QEY++LLD+KTRLE EIATYR+LLE +D K+
Sbjct: 385 QEYQVLLDVKTRLENEIATYRNLLESEDCKL 415


>gi|27894339 keratin 23 [Homo sapiens]
          Length = 422

 Score =  319 bits (817), Expect = 4e-87
 Identities = 189/432 (43%), Positives = 274/432 (63%), Gaps = 27/432 (6%)

Query: 36  SGGGGSRSISASSARFVSSGSGGGYGGGMRVCGFGGGAGSVFGGGFGGGVGGGF------ 89
           SG   S++ SAS       G+GGG+G   R   F   A +V GG  G  +   F      
Sbjct: 3   SGHSFSQTPSASF-----HGAGGGWG---RPRSFPR-APTVHGGAGGARISLSFTTRSCP 53

Query: 90  --GGGFGGGDGG-LLSGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTP 146
             GG +G G    LL GN K TMQNLNDRLASYL+KVRALEEAN  LE +I  W+Q++ P
Sbjct: 54  PPGGSWGSGRSSPLLGGNGKATMQNLNDRLASYLEKVRALEEANMKLESRILKWHQQRDP 113

Query: 147 TSPECDYSQYFKTIEELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVE 206
            S + DYSQY + I  L+++I+   + N+++IL IDNAR+A DDF LKYENE + ++ +E
Sbjct: 114 GSKK-DYSQYEENITHLQEQIVDGKMTNAQIILLIDNARMAVDDFNLKYENEHSFKKDLE 172

Query: 207 ADINGLRRVLDELTLARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAA 266
            ++ GLRR LD LT+  TDLE ++EG+ +EL  +KK+HE+EM++        VNV++D  
Sbjct: 173 IEVEGLRRTLDNLTIVTTDLEQEVEGMRKELILMKKHHEQEMEKHHVPSDFNVNVKVDTG 232

Query: 267 PGVDLTRVLAEMREQYEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLR 326
           P  DL +VL +MR++YE + +K  RD++ W+  ++  +++E AS    +Q+ + +I +L+
Sbjct: 233 PREDLIKVLEDMRQEYELIIKKKHRDLDTWYKEQSAAMSQEAAS-PATVQSRQGDIHELK 291

Query: 327 RTMQELEIELQSQLSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQN 386
           RT Q LEI+LQ+Q S K+ LEN L+ET+ RY+ +LQ +Q +I   E +L++LR E+E QN
Sbjct: 292 RTFQALEIDLQTQYSTKSALENMLSETQSRYSCKLQDMQEIISHYEEELTQLRHELERQN 351

Query: 387 QEYKMLLDIKTRLEQEIATYRSLLEGQDAKMAGIGIREASSGGGGSSSNFHIN--VEESV 444
            EY++LL IKT LE+EI TYR LLEG+       G RE S      S+   I    +E++
Sbjct: 352 NEYQVLLGIKTHLEKEITTYRRLLEGESE-----GTREESKSSMKVSATPKIKAITQETI 406

Query: 445 DGQVVSSHKREI 456
           +G++V     EI
Sbjct: 407 NGRLVLCQVNEI 418


>gi|55770882 keratin 37 [Homo sapiens]
          Length = 449

 Score =  317 bits (811), Expect = 2e-86
 Identities = 169/331 (51%), Positives = 234/331 (70%), Gaps = 6/331 (1%)

Query: 88  GFGGGFGGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPT 147
           G  G +G      L+G+EK TM+ LNDRLA+YL+KVR LE+ NA+LE  + +  + +   
Sbjct: 90  GICGAYGKNT---LNGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLE--RSKCHE 144

Query: 148 SPEC-DYSQYFKTIEELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVE 206
           S  C DY  YF+TIEEL+ KI+ +  +N+R+I++IDNA+LAADDFR+K E+E +L Q VE
Sbjct: 145 STVCPDYQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLVE 204

Query: 207 ADINGLRRVLDELTLARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAA 266
           AD  G +++LD+ TLA+ DLE Q E L EE   LK NHE+E+K   SQL  +  +E+D  
Sbjct: 205 ADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRIELDIE 264

Query: 267 PGVDLTRVLAEMREQYEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLR 326
           P +DL RVL EMR QYEAM E N +DVE WF +++E ++ +  S +E +Q  ++EI +LR
Sbjct: 265 PTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILELR 324

Query: 327 RTMQELEIELQSQLSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQN 386
            T+  LE+E Q+Q ++K  L+NSL E E RY T+L Q+Q LI  LE QLSE+R ++E QN
Sbjct: 325 CTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQN 384

Query: 387 QEYKMLLDIKTRLEQEIATYRSLLEGQDAKM 417
           QEY++LLD+K RLE EIATYR+LLE +D K+
Sbjct: 385 QEYQVLLDVKARLENEIATYRNLLESEDCKL 415


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.132    0.363 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,669,990
Number of Sequences: 37866
Number of extensions: 806085
Number of successful extensions: 24292
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 470
Number of HSP's successfully gapped in prelim test: 555
Number of HSP's that attempted gapping in prelim test: 6550
Number of HSP's gapped (non-prelim): 7149
length of query: 456
length of database: 18,247,518
effective HSP length: 106
effective length of query: 350
effective length of database: 14,233,722
effective search space: 4981802700
effective search space used: 4981802700
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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