BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|24234699 keratin 19 [Homo sapiens] (400 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|24234699 keratin 19 [Homo sapiens] 771 0.0 gi|24430190 keratin 15 [Homo sapiens] 496 e-140 gi|4557701 keratin 17 [Homo sapiens] 494 e-140 gi|24430192 keratin 16 [Homo sapiens] 486 e-137 gi|15431310 keratin 14 [Homo sapiens] 484 e-137 gi|131412228 keratin 13 isoform b [Homo sapiens] 472 e-133 gi|131412225 keratin 13 isoform a [Homo sapiens] 472 e-133 gi|195972866 keratin 10 [Homo sapiens] 434 e-122 gi|4557699 keratin 12 [Homo sapiens] 432 e-121 gi|192807292 keratin 24 [Homo sapiens] 401 e-112 gi|4504927 keratin 36 [Homo sapiens] 395 e-110 gi|153945736 keratin 27 [Homo sapiens] 387 e-107 gi|94538345 keratin 35 [Homo sapiens] 381 e-106 gi|27894337 keratin 20 [Homo sapiens] 379 e-105 gi|114431246 keratin 25D [Homo sapiens] 376 e-104 gi|55956899 keratin 9 [Homo sapiens] 369 e-102 gi|31559829 keratin 25 [Homo sapiens] 369 e-102 gi|116488398 keratin 32 [Homo sapiens] 363 e-100 gi|14917115 keratin 31 [Homo sapiens] 360 e-99 gi|14917117 keratin 33A [Homo sapiens] 360 1e-99 gi|10337581 type I hair keratin 3B [Homo sapiens] 359 2e-99 gi|14917119 keratin 34 [Homo sapiens] 355 4e-98 gi|31559815 keratin 26 [Homo sapiens] 348 4e-96 gi|40354195 keratin 18 [Homo sapiens] 334 7e-92 gi|4557888 keratin 18 [Homo sapiens] 334 7e-92 gi|125490370 type I hair keratin KA36 [Homo sapiens] 326 2e-89 gi|27894339 keratin 23 [Homo sapiens] 320 2e-87 gi|148277620 type I hair keratin KA35 [Homo sapiens] 317 2e-86 gi|15431318 keratin 38 [Homo sapiens] 311 5e-85 gi|55770882 keratin 37 [Homo sapiens] 305 6e-83 >gi|24234699 keratin 19 [Homo sapiens] Length = 400 Score = 771 bits (1992), Expect = 0.0 Identities = 400/400 (100%), Positives = 400/400 (100%) Query: 1 MTSYSYRQSSATSSFGGLGGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGA 60 MTSYSYRQSSATSSFGGLGGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGA Sbjct: 1 MTSYSYRQSSATSSFGGLGGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGA 60 Query: 61 YGGGYGGVLTASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQG 120 YGGGYGGVLTASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQG Sbjct: 61 YGGGYGGVLTASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQG 120 Query: 121 PGPSRDYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVE 180 PGPSRDYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVE Sbjct: 121 PGPSRDYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVE 180 Query: 181 ADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSA 240 ADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSA Sbjct: 181 ADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSA 240 Query: 241 PGTDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLR 300 PGTDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLR Sbjct: 241 PGTDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLR 300 Query: 301 RTLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQN 360 RTLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQN Sbjct: 301 RTLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQN 360 Query: 361 QEYQRLMDIKSRLEQEIATYRSLLEGQEDHYNNLSASKVL 400 QEYQRLMDIKSRLEQEIATYRSLLEGQEDHYNNLSASKVL Sbjct: 361 QEYQRLMDIKSRLEQEIATYRSLLEGQEDHYNNLSASKVL 400 >gi|24430190 keratin 15 [Homo sapiens] Length = 456 Score = 496 bits (1276), Expect = e-140 Identities = 262/415 (63%), Positives = 311/415 (74%), Gaps = 28/415 (6%) Query: 1 MTSYSYRQSSATSSFGGLGGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGA 60 MT+ + SS+T G GGS+ G G F S+ GG G R +S SSARFVSS S G Sbjct: 1 MTTTFLQTSSSTFGGGSTRGGSLLAGGG-GFGGGSLSGGGGSRSISASSARFVSSGSGGG 59 Query: 61 YGGG-------------------------YGGVLTASDG-LLAGNEKLTMQNLNDRLASY 94 YGGG +GG DG LL+GNEK+TMQNLNDRLASY Sbjct: 60 YGGGMRVCGFGGGAGSVFGGGFGGGVGGGFGGGFGGGDGGLLSGNEKITMQNLNDRLASY 119 Query: 95 LDKVRALEAANGELEVKIRDWYQKQGP-GPSRDYSHYYTTIQDLRDKILGATIENSRIVL 153 LDKVRALE AN +LEVKI DWYQKQ P P DYS Y+ TI++LRDKI+ TI+NSR++L Sbjct: 120 LDKVRALEEANADLEVKIHDWYQKQTPTSPECDYSQYFKTIEELRDKIMATTIDNSRVIL 179 Query: 154 QIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAY 213 +IDNARLAADDFR K+E E ALR VEADINGLRRVLDELTLARTDLEMQIEGL EELAY Sbjct: 180 EIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDELTLARTDLEMQIEGLNEELAY 239 Query: 214 LKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQNRKDAEAWFTS 273 LKKNHEEE+ Q+ GQV+VE+D+APG DL ++L++MR QYE MAE+NR+D EAWF S Sbjct: 240 LKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEMREQYEAMAEKNRRDVEAWFFS 299 Query: 274 RTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQSQLSMKAALEDTLAETEARFGA 333 +TEELN+EVA +TE +Q S++E+TDLRRT+Q LEIELQSQLSMKA LE++LAETE R+ Sbjct: 300 KTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQSQLSMKAGLENSLAETECRYAT 359 Query: 334 QLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSRLEQEIATYRSLLEGQE 388 QL IQ LI G+EAQL ++R + E QNQEY+ L+DIK+RLEQEIATYRSLLEGQ+ Sbjct: 360 QLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTRLEQEIATYRSLLEGQD 414 >gi|4557701 keratin 17 [Homo sapiens] Length = 432 Score = 494 bits (1272), Expect = e-140 Identities = 256/389 (65%), Positives = 312/389 (80%), Gaps = 6/389 (1%) Query: 6 YRQSSATSSFGGLGGGS----VRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAY 61 + SS+ GLGGGS R G+ + + G +GG G ++ + + S S G+ Sbjct: 8 FTSSSSIKGSSGLGGGSSRTSCRLSGGLGAGSCRL-GSAGGLGSTLGGSSYSSCYSFGS- 65 Query: 62 GGGYGGVLTASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGP 121 GGGYG DGLLAG EK TMQNLNDRLASYLDKVRALE AN ELEVKIRDWYQ+Q P Sbjct: 66 GGGYGSSFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQAP 125 Query: 122 GPSRDYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEA 181 GP+RDYS YY TI++L++KIL AT++N+ I+LQIDNARLAADDFRTKFETEQALR+SVEA Sbjct: 126 GPARDYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALRLSVEA 185 Query: 182 DINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAP 241 DINGLRRVLDELTLAR DLEMQIE LKEELAYLKKNHEEE++ LRGQVGG+++VE+D+AP Sbjct: 186 DINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVEMDAAP 245 Query: 242 GTDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRR 301 G DL++IL++MR QYE MAE+NRKDAE WF S+TEELNREVA ++E +Q +SE+++LRR Sbjct: 246 GVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEISELRR 305 Query: 302 TLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQ 361 T+Q LEIELQSQLSMKA+LE LAETE R+ QL+ IQ LI +E QL +R + E+QNQ Sbjct: 306 TMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQ 365 Query: 362 EYQRLMDIKSRLEQEIATYRSLLEGQEDH 390 EY+ L+D+K+RLEQEIATYR LLEG++ H Sbjct: 366 EYKILLDVKTRLEQEIATYRRLLEGEDAH 394 >gi|24430192 keratin 16 [Homo sapiens] Length = 473 Score = 486 bits (1251), Expect = e-137 Identities = 263/435 (60%), Positives = 322/435 (74%), Gaps = 39/435 (8%) Query: 1 MTSYSYRQSSATSSF-------GGLGGGSVRFGP---GVAFRAPSIHGGS---------- 40 MT+ S RQ +++SS GG+GGGS R G + RAPS +GG Sbjct: 1 MTTCS-RQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGGGLSVSSRFSSG 59 Query: 41 ------GGRGVSVSSARFVSSSSSGAYGGG------------YGGVLTASDGLLAGNEKL 82 GG G SS+ S G YGGG +GG DGLL G+EK+ Sbjct: 60 GACGLGGGYGGGFSSSSSFGSGFGGGYGGGLGAGFGGGLGAGFGGGFAGGDGLLVGSEKV 119 Query: 83 TMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPGPSRDYSHYYTTIQDLRDKIL 142 TMQNLNDRLASYLDKVRALE AN +LEVKIRDWYQ+Q P +DYS Y+ TI+DLR+KI+ Sbjct: 120 TMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIKDYSPYFKTIEDLRNKII 179 Query: 143 GATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTLARTDLEM 202 ATIEN++ +LQIDNARLAADDFRTK+E E ALR +VEAD+NGLRRVLDELTLARTDLEM Sbjct: 180 AATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDELTLARTDLEM 239 Query: 203 QIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQ 262 QIEGLKEELAYL+KNHEEE+ LRGQ GG V+VE+D+APG DL++IL++MR QYE MAE+ Sbjct: 240 QIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEMRDQYEQMAEK 299 Query: 263 NRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQSQLSMKAALED 322 NR+DAE WF S+TEELN+EVA ++E +Q SRSEVT+LRR LQGLEIELQSQLSMKA+LE+ Sbjct: 300 NRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQSQLSMKASLEN 359 Query: 323 TLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSRLEQEIATYRS 382 +L ET+ R+ QL+ IQ LI +E QL +R + E+Q+QEYQ L+D+K+RLEQEIATYR Sbjct: 360 SLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTRLEQEIATYRR 419 Query: 383 LLEGQEDHYNNLSAS 397 LLEG++ H ++ AS Sbjct: 420 LLEGEDAHLSSQQAS 434 >gi|15431310 keratin 14 [Homo sapiens] Length = 472 Score = 484 bits (1246), Expect = e-137 Identities = 263/433 (60%), Positives = 327/433 (75%), Gaps = 45/433 (10%) Query: 1 MTSYSYRQSSATSSF-------GGLGGGSVRFGP---GVAFRAPSIHGGSGGRGVSVSSA 50 MT+ S RQ +++SS GG+GGGS R G + RAPS +GG G+SVSS+ Sbjct: 1 MTTCS-RQFTSSSSMKGSCGIGGGIGGGSSRISSVLAGGSCRAPSTYGG----GLSVSSS 55 Query: 51 RFVS--------------SSSSGAYG----------------GGYGGVLTASDGLLAGNE 80 RF S SSSS ++G GG+GG DGLL G+E Sbjct: 56 RFSSGGAYGLGGGYGGGFSSSSSSFGSGFGGGYGGGLGAGLGGGFGGGFAGGDGLLVGSE 115 Query: 81 KLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPGPSRDYSHYYTTIQDLRDK 140 K+TMQNLNDRLASYLDKVRALE AN +LEVKIRDWYQ+Q P +DYS Y+ TI+DLR+K Sbjct: 116 KVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIKDYSPYFKTIEDLRNK 175 Query: 141 ILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTLARTDL 200 IL AT++N+ ++LQIDNARLAADDFRTK+ETE LRMSVEADINGLRRVLDELTLAR DL Sbjct: 176 ILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDELTLARADL 235 Query: 201 EMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKILSDMRSQYEVMA 260 EMQIE LKEELAYLKKNHEEE++ LRGQVGG V+VE+D+APG DL++IL++MR QYE MA Sbjct: 236 EMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMA 295 Query: 261 EQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQSQLSMKAAL 320 E+NRKDAE WF ++TEELNREVA ++E +Q +SE+++LRRT+Q LEIELQSQLSMKA+L Sbjct: 296 EKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQSQLSMKASL 355 Query: 321 EDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSRLEQEIATY 380 E++L ET+ R+ QLA IQ +I +E QL +R + E+QNQEY+ L+D+K+RLEQEIATY Sbjct: 356 ENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATY 415 Query: 381 RSLLEGQEDHYNN 393 R LLEG++ H ++ Sbjct: 416 RRLLEGEDAHLSS 428 >gi|131412228 keratin 13 isoform b [Homo sapiens] Length = 420 Score = 472 bits (1215), Expect = e-133 Identities = 255/422 (60%), Positives = 304/422 (72%), Gaps = 55/422 (13%) Query: 8 QSSATSSFGGLGGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAYGGG--- 64 QSS+ S GG GGGS + G GGRGVS S RFVS S+G YGGG Sbjct: 6 QSSSASYGGGFGGGSCQLG--------------GGRGVSTCSTRFVSGGSAGGYGGGVSC 51 Query: 65 ---------------------YGGVL----------------TASDGLLAGNEKLTMQNL 87 YGG L GLL GNEK+TMQNL Sbjct: 52 GFGGGAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNL 111 Query: 88 NDRLASYLDKVRALEAANGELEVKIRDWYQKQGPG-PSRDYSHYYTTIQDLRDKILGATI 146 NDRLASYL+KVRALE AN +LEVKIRDW+ KQ P P RDYS YY TI++LRDKIL ATI Sbjct: 112 NDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATI 171 Query: 147 ENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEG 206 EN+R++L+IDNARLAADDFR K+E E ALR SVEADINGLRRVLDELTL++TDLEMQIE Sbjct: 172 ENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIES 231 Query: 207 LKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQNRKD 266 L EELAY+KKNHEEE+ QV GQV+VE+D+ PG DL ++L++MR QYE MAE+NR+D Sbjct: 232 LNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRD 291 Query: 267 AEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQSQLSMKAALEDTLAE 326 AE WF +++ ELN+EV+ +T +Q S++E+T+LRRTLQGLEIELQSQLSMKA LE+T+AE Sbjct: 292 AEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAE 351 Query: 327 TEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSRLEQEIATYRSLLEG 386 TE R+ QL IQ LIS IEAQL ++R++ E QNQEY+ L+DIK+RLEQEIATYRSLLEG Sbjct: 352 TECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEG 411 Query: 387 QE 388 Q+ Sbjct: 412 QD 413 >gi|131412225 keratin 13 isoform a [Homo sapiens] Length = 458 Score = 472 bits (1215), Expect = e-133 Identities = 255/422 (60%), Positives = 304/422 (72%), Gaps = 55/422 (13%) Query: 8 QSSATSSFGGLGGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAYGGG--- 64 QSS+ S GG GGGS + G GGRGVS S RFVS S+G YGGG Sbjct: 6 QSSSASYGGGFGGGSCQLG--------------GGRGVSTCSTRFVSGGSAGGYGGGVSC 51 Query: 65 ---------------------YGGVL----------------TASDGLLAGNEKLTMQNL 87 YGG L GLL GNEK+TMQNL Sbjct: 52 GFGGGAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNL 111 Query: 88 NDRLASYLDKVRALEAANGELEVKIRDWYQKQGPG-PSRDYSHYYTTIQDLRDKILGATI 146 NDRLASYL+KVRALE AN +LEVKIRDW+ KQ P P RDYS YY TI++LRDKIL ATI Sbjct: 112 NDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATI 171 Query: 147 ENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEG 206 EN+R++L+IDNARLAADDFR K+E E ALR SVEADINGLRRVLDELTL++TDLEMQIE Sbjct: 172 ENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIES 231 Query: 207 LKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQNRKD 266 L EELAY+KKNHEEE+ QV GQV+VE+D+ PG DL ++L++MR QYE MAE+NR+D Sbjct: 232 LNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRD 291 Query: 267 AEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQSQLSMKAALEDTLAE 326 AE WF +++ ELN+EV+ +T +Q S++E+T+LRRTLQGLEIELQSQLSMKA LE+T+AE Sbjct: 292 AEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAE 351 Query: 327 TEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSRLEQEIATYRSLLEG 386 TE R+ QL IQ LIS IEAQL ++R++ E QNQEY+ L+DIK+RLEQEIATYRSLLEG Sbjct: 352 TECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEG 411 Query: 387 QE 388 Q+ Sbjct: 412 QD 413 >gi|195972866 keratin 10 [Homo sapiens] Length = 584 Score = 434 bits (1117), Expect = e-122 Identities = 234/386 (60%), Positives = 286/386 (74%), Gaps = 16/386 (4%) Query: 5 SYRQSSATSSFGGLGGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAYGGG 64 S+R S +SSFGG GGS FG G +F S GGS G G G +GGG Sbjct: 84 SFRGSYGSSSFGGSYGGS--FGGG-SFGGGSFGGGSFGGG----------GFGGGGFGGG 130 Query: 65 YGGVLTASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQG---P 121 +GG GLL+GNEK+TMQNLNDRLASYLDKVRALE +N ELE KI++WY+K G Sbjct: 131 FGGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSHQ 190 Query: 122 GPSRDYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEA 181 G RDYS YY TI DL+++IL T +N+ I+LQIDNARLAADDFR K+E E ALR SVEA Sbjct: 191 GEPRDYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEA 250 Query: 182 DINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAP 241 DINGLRRVLDELTL + DLEMQIE L EELAYLKKNHEEE+ LR G V+VE+++AP Sbjct: 251 DINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMNAAP 310 Query: 242 GTDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRR 301 G DL ++L++MRSQYE +AEQNRKDAEAWF +++EL E+ + EQ+ +SE+T+LRR Sbjct: 311 GVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELRR 370 Query: 302 TLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQ 361 +Q LEIELQSQL++K +LE +LAETE R+ QL+ IQA IS +E QL +RA++E QN Sbjct: 371 NVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNT 430 Query: 362 EYQRLMDIKSRLEQEIATYRSLLEGQ 387 EYQ+L+DIK RLE EI TYRSLLEG+ Sbjct: 431 EYQQLLDIKIRLENEIQTYRSLLEGE 456 Score = 38.9 bits (89), Expect = 0.008 Identities = 26/68 (38%), Positives = 31/68 (45%), Gaps = 2/68 (2%) Query: 2 TSYSYRQSSATSSFGGLGGGSVR--FGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSG 59 T S + +S GG GGGS +G G + S G GG G S SS G Sbjct: 448 TYRSLLEGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGG 507 Query: 60 AYGGGYGG 67 + GGGYGG Sbjct: 508 SSGGGYGG 515 Score = 38.5 bits (88), Expect = 0.011 Identities = 31/77 (40%), Positives = 35/77 (45%), Gaps = 9/77 (11%) Query: 4 YSYRQSSATSSFGGLGGGSVRFGPGVA----FRAPSIHGGSGGRGVSVSSARFVSSSSSG 59 Y S SS GG GGGS G G + + S GG GG G S SSS G Sbjct: 499 YGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGG---GSSSGG 555 Query: 60 AYGGG--YGGVLTASDG 74 YGGG GG ++S G Sbjct: 556 GYGGGSSSGGHKSSSSG 572 Score = 34.3 bits (77), Expect = 0.20 Identities = 25/60 (41%), Positives = 27/60 (45%), Gaps = 1/60 (1%) Query: 9 SSATSSFGGLGGGSVRFGPGVAFRAPSIHGGSGGRGV-SVSSARFVSSSSSGAYGGGYGG 67 SS S GG GG G + S GGS G G SS+ SSSG YGGG G Sbjct: 477 SSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSG 536 Score = 32.0 bits (71), Expect = 1.0 Identities = 28/72 (38%), Positives = 29/72 (40%), Gaps = 8/72 (11%) Query: 4 YSYRQSSATSSFGGLGGG---SVRFGPGVAFRAPSIHGGSGGRGVSV-----SSARFVSS 55 Y S SS GG GGG S G G GG G G S SS+ Sbjct: 473 YGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGG 532 Query: 56 SSSGAYGGGYGG 67 SSG GGGYGG Sbjct: 533 GSSGGGGGGYGG 544 >gi|4557699 keratin 12 [Homo sapiens] Length = 494 Score = 432 bits (1110), Expect = e-121 Identities = 238/406 (58%), Positives = 299/406 (73%), Gaps = 25/406 (6%) Query: 7 RQSSATSSFGGLGGGSVRFGP--GVAFRAPSIHGGS----GGRGVSVSSA------RFVS 54 R SA+S G GG + FG G F A S+ G S GG G S++ R + Sbjct: 31 RGMSASSVGSGYGGSAFGFGASCGGGFSAASMFGSSSGFGGGSGSSMAGGLGAGYGRALG 90 Query: 55 SSSSGAYGGGYGG--------VLTASDG-LLAGNEKLTMQNLNDRLASYLDKVRALEAAN 105 S G G G+GG +L+ +DG LL+G+EK TMQNLNDRLASYLDKVRALE AN Sbjct: 91 GGSFGGLGMGFGGSPGGGSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEAN 150 Query: 106 GELEVKIRDWYQKQGPGPS----RDYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLA 161 ELE KIR+WY+ +G G + DYS YY I+DLR+KI+ A+I N++++LQIDNARLA Sbjct: 151 TELENKIREWYETRGTGTADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDNARLA 210 Query: 162 ADDFRTKFETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEE 221 A+DFR K+E E ALR VEADINGLRRVLDELTL RTDLEMQIE L EELAY+KKNHE+E Sbjct: 211 AEDFRMKYENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEDE 270 Query: 222 ISTLRGQVGGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNRE 281 + + R G+VSVE+D+APG DL ++L+DMR+QYE +AEQNRKDAEAWF ++ EL +E Sbjct: 271 LQSFRVGGPGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKE 330 Query: 282 VAGHTEQLQMSRSEVTDLRRTLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQAL 341 ++ +TEQLQ S+SEVTDLRR Q LEIELQSQL+MK +LED+LAE E + AQL+ +Q L Sbjct: 331 ISTNTEQLQSSKSEVTDLRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQL 390 Query: 342 ISGIEAQLGDVRADSERQNQEYQRLMDIKSRLEQEIATYRSLLEGQ 387 IS +EAQL VRAD+ERQN ++QRL+++K+RLE EI TYR LL+G+ Sbjct: 391 ISNLEAQLLQVRADAERQNVDHQRLLNVKARLELEIETYRRLLDGE 436 >gi|192807292 keratin 24 [Homo sapiens] Length = 525 Score = 401 bits (1030), Expect = e-112 Identities = 213/386 (55%), Positives = 282/386 (73%), Gaps = 13/386 (3%) Query: 10 SATSSFGGLGGGSVRFGPGVAFRAPSIHG-GSGGRGVSVSSARFVSSSSSG--AYGGGYG 66 S FGG G FG G +F S G GSG G S+RF S ++ G +YGGG G Sbjct: 72 SVGGGFGGASGSGTGFGGGSSFGGVSGFGRGSGFCG----SSRFSSGATGGFYSYGGGMG 127 Query: 67 GVLTASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPGPS-- 124 G + GL +G EK TMQNLNDRLA+YLDKVRALE AN +LE KI++WY K GPG Sbjct: 128 GGV-GDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDG 186 Query: 125 ---RDYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEA 181 RDYS YY+ I+DLR++I+ AT+EN+ I+L IDNARLAADDFR K+E E LR SVEA Sbjct: 187 GSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEA 246 Query: 182 DINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAP 241 DINGLR+VLD+LT+ R+DLEMQIE EELAYL+KNHEEE+ ++G GG+V+VE+++AP Sbjct: 247 DINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNAAP 306 Query: 242 GTDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRR 301 GTDL K+L+DMR+QYE +AEQNR++AE F ++ L +++ +++E+T+L+R Sbjct: 307 GTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITELKR 366 Query: 302 TLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQ 361 TLQ LEIELQSQL+MK++LE TLA+TEA + AQL+ IQ IS +E ++ + +++ QN Sbjct: 367 TLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNA 426 Query: 362 EYQRLMDIKSRLEQEIATYRSLLEGQ 387 EY++L+DIK+RLE EI TYR LL+G+ Sbjct: 427 EYKQLLDIKTRLEVEIETYRRLLDGE 452 Score = 32.3 bits (72), Expect = 0.78 Identities = 21/63 (33%), Positives = 29/63 (46%), Gaps = 5/63 (7%) Query: 5 SYRQSSATSSFGGLGGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAYGGG 64 S R ++S+ GG S G S G GG +S+ +S SSGA+GG Sbjct: 9 SSRAGGSSSARVSAGGSSFSSGSRCGLGGSSAQGFRGG-----ASSCSLSGGSSGAFGGS 63 Query: 65 YGG 67 +GG Sbjct: 64 FGG 66 >gi|4504927 keratin 36 [Homo sapiens] Length = 467 Score = 395 bits (1015), Expect = e-110 Identities = 211/379 (55%), Positives = 267/379 (70%), Gaps = 3/379 (0%) Query: 10 SATSSFGGLGGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAYGGGYGGVL 69 S SS +G V G A S G G G + + S + + G G Sbjct: 26 SRVSSIRSVGSCRVPSLAGAAGYISSARSGLSGLGSCLPGSYLSSECHTSGFVGSGGWFC 85 Query: 70 TASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPGPSRDYSH 129 +G G+EK TMQ LNDRLA+YL+KVR LE N ELE +I++WY+ Q P DY Sbjct: 86 ---EGSFNGSEKETMQFLNDRLANYLEKVRQLERENAELESRIQEWYEFQIPYICPDYQS 142 Query: 130 YYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRV 189 Y+ TI+D + KIL EN+R+VLQIDNA+LAADDFRTK+ETE +LR VEADINGLRR+ Sbjct: 143 YFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTKYETELSLRQLVEADINGLRRI 202 Query: 190 LDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKIL 249 LDELTL + DLE Q+E LKEEL LKKNHEEE+S LR Q+G +++VEVD+AP DL KIL Sbjct: 203 LDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQLGDRLNVEVDAAPPVDLNKIL 262 Query: 250 SDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIE 309 DMR QYE + E NR+D EAWF ++TEELN++V +EQLQ ++E+ +LRRT+ LEIE Sbjct: 263 EDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQLQCCQTEIIELRRTVNALEIE 322 Query: 310 LQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDI 369 LQ+Q SM+ +LE TLAETEAR+ +QLA +Q LIS +EAQL ++R D ERQNQEYQ L+D+ Sbjct: 323 LQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSEIRCDLERQNQEYQVLLDV 382 Query: 370 KSRLEQEIATYRSLLEGQE 388 K+RLE EIATYR LLEG++ Sbjct: 383 KARLEGEIATYRHLLEGED 401 >gi|153945736 keratin 27 [Homo sapiens] Length = 459 Score = 387 bits (993), Expect = e-107 Identities = 214/396 (54%), Positives = 275/396 (69%), Gaps = 13/396 (3%) Query: 5 SYRQSSATSSFGGLGG-GSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAYGG 63 S R SS + G GG GSVR G A G G G S A F SSS+G YGG Sbjct: 2 SVRFSSTSRRLGSCGGTGSVRLSSGGAGFGAGNTCGVPGIGSGFSCA-FGGSSSAGGYGG 60 Query: 64 GYGG------VLTASD-GLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWY 116 G GG T ++ GLL+GNEK+TMQNLNDRLASYL+ VRALE AN +LE KI+ WY Sbjct: 61 GLGGGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWY 120 Query: 117 QKQGPGPSR----DYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETE 172 +K GPG R DYS Y+ I +L+++I+ AT N+ +VLQ DNARL ADDFR KFE E Sbjct: 121 EKFGPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENE 180 Query: 173 QALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQ 232 AL SVEADINGLRRVLDELTL RTDLE+Q+E L EELAYLKKNHEEE+ L+ GG Sbjct: 181 LALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAGGN 240 Query: 233 VSVEVDSAPGTDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMS 292 V+VE+++APG DL +L++MR++YE +AEQNR+DAEAWF ++ L ++++ + Sbjct: 241 VNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSA 300 Query: 293 RSEVTDLRRTLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDV 352 R+E+ +++RTLQ LEIELQS L+ K +LE +L ETE+ + AQLA IQA I +E QL V Sbjct: 301 RNELIEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQV 360 Query: 353 RADSERQNQEYQRLMDIKSRLEQEIATYRSLLEGQE 388 R ++E Q EY++L+DIK LE+EI TY L++G++ Sbjct: 361 RTETEGQKLEYEQLLDIKVHLEKEIETYCLLIDGED 396 >gi|94538345 keratin 35 [Homo sapiens] Length = 455 Score = 381 bits (978), Expect = e-106 Identities = 206/402 (51%), Positives = 279/402 (69%), Gaps = 30/402 (7%) Query: 9 SSATSSFGGLGGGSVRFG----------PGVAFRAPSIHGGSGGRGVS------------ 46 S + S GG GGS R P ++ A S S G G S Sbjct: 12 SGSLKSPGGASGGSTRVSAMYSSSSCKLPSLSPVARSFSACSVGLGRSSYRATSCLPALC 71 Query: 47 VSSARFVSSSSSGAYGGGYGGVLTASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANG 106 + + F +S S G GG +G +G+L GNEK TMQ+LNDRLA YL+KVR LE N Sbjct: 72 LPAGGFATSYSGG--GGWFG------EGILTGNEKETMQSLNDRLAGYLEKVRQLEQENA 123 Query: 107 ELEVKIRDWYQKQGPGPSRDYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFR 166 LE +IR+W ++Q P DY Y+ TI++L+ K L + EN+R+V++IDNA+LAADDFR Sbjct: 124 SLESRIREWCEQQVPYMCPDYQSYFRTIEELQKKTLCSKAENARLVVEIDNAKLAADDFR 183 Query: 167 TKFETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLR 226 TK+ETE +LR VE+DINGLRR+LD+LTL ++DLE Q+E LKEEL LKKNHEEE+++LR Sbjct: 184 TKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKNHEEEVNSLR 243 Query: 227 GQVGGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHT 286 Q+G +++VEVD+AP DL ++L +MR QYE + E NR+DAE W +++EELN++V + Sbjct: 244 CQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEELNQQVVSSS 303 Query: 287 EQLQMSRSEVTDLRRTLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIE 346 EQLQ ++E+ +LRRT+ LEIELQ+Q SM+ ALE TLAETEAR+ +QLA +Q +I+ +E Sbjct: 304 EQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQMQCMITNVE 363 Query: 347 AQLGDVRADSERQNQEYQRLMDIKSRLEQEIATYRSLLEGQE 388 AQL ++RAD ERQNQEYQ L+D+++RLE EI TYR LLE ++ Sbjct: 364 AQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESED 405 >gi|27894337 keratin 20 [Homo sapiens] Length = 424 Score = 379 bits (974), Expect = e-105 Identities = 190/355 (53%), Positives = 266/355 (74%), Gaps = 9/355 (2%) Query: 34 PSIHGGSGGRGVSVSSARFVSSSSSGAYGGGYGGVLTASDGLLAGNEKLTMQNLNDRLAS 93 PS++GG+GGRG+ +S++R + YG LT L GNEK+ MQNLNDRLAS Sbjct: 33 PSVYGGAGGRGIRISNSRHTVN---------YGSDLTGGGDLFVGNEKMAMQNLNDRLAS 83 Query: 94 YLDKVRALEAANGELEVKIRDWYQKQGPGPSRDYSHYYTTIQDLRDKILGATIENSRIVL 153 YL+KVR LE +N +LEV+I+ WY+ P RDYS YY I++LR +I A ++N+R VL Sbjct: 84 YLEKVRTLEQSNSKLEVQIKQWYETNAPRAGRDYSAYYRQIEELRSQIKDAQLQNARCVL 143 Query: 154 QIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAY 213 QIDNA+LAA+DFR K+ETE+ +R++VEAD+ GL +V D+LTL +TDLE+QIE L ++LA Sbjct: 144 QIDNAKLAAEDFRLKYETERGIRLTVEADLQGLNKVFDDLTLHKTDLEIQIEELNKDLAL 203 Query: 214 LKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQNRKDAEAWFTS 273 LKK H+EE+ L +G V+VEVD+APG +L I+++MR +YEVMA++N ++A+ F Sbjct: 204 LKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMNEMRQKYEVMAQKNLQEAKEQFER 263 Query: 274 RTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQSQLSMKAALEDTLAETEARFGA 333 +T L ++V +TE+L+ + ++T+LRRT Q LEIELQS LSMK +LE TL ET+AR+ + Sbjct: 264 QTAVLQQQVTVNTEELKGTEVQLTELRRTSQSLEIELQSHLSMKESLEHTLEETKARYSS 323 Query: 334 QLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSRLEQEIATYRSLLEGQE 388 QLA++Q+L+S +EAQL +R++ ERQN EY L+DIK+RLEQEIATYR LLEG++ Sbjct: 324 QLANLQSLLSSLEAQLMQIRSNMERQNNEYHILLDIKTRLEQEIATYRRLLEGED 378 >gi|114431246 keratin 25D [Homo sapiens] Length = 464 Score = 376 bits (966), Expect = e-104 Identities = 206/402 (51%), Positives = 267/402 (66%), Gaps = 35/402 (8%) Query: 19 GGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAYGGGYGGVLTASD----- 73 G GSVR ++GG+G G S S S A GGG G V S Sbjct: 17 GAGSVR----------PLNGGAGFAGSSACGGSVAGSEFSCALGGGLGSVPGGSHAGGAL 66 Query: 74 -------------GLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQG 120 GLL+GNEK+TMQNLNDRLASYLD VRALE AN ELE KI+ WY+K G Sbjct: 67 GNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYG 126 Query: 121 PGPSR----DYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALR 176 PG R DYS Y+ TI+DL++KI+ +T N+ ++LQIDNARLAADDFR K+E E L Sbjct: 127 PGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLH 186 Query: 177 MSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVE 236 +VEADINGLRRVLDELTL RTD E+Q E L EE+ YLKKNHEEE+ L+ GG V+VE Sbjct: 187 QNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVE 246 Query: 237 VDSAPGTDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEV 296 +++APG DLA +L++MR++YE +AEQNRKDAEAWF ++ L ++++ + +RS++ Sbjct: 247 MNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQL 306 Query: 297 TDLRRTLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADS 356 T++RRTLQ LEI+LQS ++ K +LE +L ETE+ + QLA IQA I +E QL VR ++ Sbjct: 307 TEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTET 366 Query: 357 ERQNQEYQRLMDIKSRLEQEIATYRSLLEGQEDHYNNLSASK 398 E Q EY+ L+D+K LE+EI TY L++G N+ S SK Sbjct: 367 EGQKLEYEHLLDVKVHLEKEIETYCRLIDGDG---NSCSKSK 405 >gi|55956899 keratin 9 [Homo sapiens] Length = 623 Score = 369 bits (947), Expect = e-102 Identities = 206/393 (52%), Positives = 264/393 (67%), Gaps = 4/393 (1%) Query: 10 SATSSFGGLGGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAYG-GGYGGV 68 SA+S GG GGGS FG G + S GG GG S F SG G GG+GG Sbjct: 82 SASSLGGGFGGGSRGFG-GASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGGFGGG 140 Query: 69 LTASDG-LLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPGP-SRD 126 DG +L NEK TMQ LN RLASYLDKV+ALE AN +LE KI+DWY K+GP ++ Sbjct: 141 AGGGDGGILTANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQKN 200 Query: 127 YSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADINGL 186 YS YY TI DL+D+I+ T+ N++ +L IDN R+ DDFR KFE EQ LR V+ADINGL Sbjct: 201 YSPYYNTIDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGL 260 Query: 187 RRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLA 246 R+VLD LT+ ++DLEMQ E L+EEL LKKNH+EE+S L GQ G V+VE++ APG DL Sbjct: 261 RQVLDNLTMEKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGKDLT 320 Query: 247 KILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGL 306 K L+DMR +YE + +NRKD E + ++ ++ EV+ +++Q S EVT LR +Q L Sbjct: 321 KTLNDMRQEYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQEL 380 Query: 307 EIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQRL 366 EIELQSQLS KAALE +L +T+ R+ QL IQ IS +EAQ+ DVR + E QNQEY L Sbjct: 381 EIELQSQLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLL 440 Query: 367 MDIKSRLEQEIATYRSLLEGQEDHYNNLSASKV 399 + IK RLE+EI TY +LLEG ++ + + A K+ Sbjct: 441 LSIKMRLEKEIETYHNLLEGGQEDFESSGAGKI 473 Score = 36.2 bits (82), Expect = 0.054 Identities = 25/67 (37%), Positives = 29/67 (43%), Gaps = 1/67 (1%) Query: 14 SFGGLGGGS-VRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAYGGGYGGVLTAS 72 S GG GGGS R G G ++ S GG G G S S S G + GG GG Sbjct: 502 SGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGG 561 Query: 73 DGLLAGN 79 G G+ Sbjct: 562 SGSGGGS 568 Score = 34.7 bits (78), Expect = 0.16 Identities = 24/64 (37%), Positives = 25/64 (39%), Gaps = 5/64 (7%) Query: 3 SYSYRQSSATSSFGGLGGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAYG 62 SY S S GG GGGS G S G SGG G + S G YG Sbjct: 519 SYGGGSGSGGGSGGGYGGGS-----GGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYG 573 Query: 63 GGYG 66 GG G Sbjct: 574 GGSG 577 Score = 33.9 bits (76), Expect = 0.27 Identities = 30/80 (37%), Positives = 36/80 (45%), Gaps = 12/80 (15%) Query: 3 SYSYRQSSATSSFGGLG-GGSVRFGPGVAFRAPSIHGGSGGR-----GVSVSSARFVSSS 56 S SY S GGLG GGS+R + + S GG GGR G S+R Sbjct: 7 SSSYLSRSGGGGGGGLGSGGSIR--SSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRG 64 Query: 57 SSG----AYGGGYGGVLTAS 72 G +YGGG GG +AS Sbjct: 65 GGGSFGYSYGGGSGGGFSAS 84 Score = 32.3 bits (72), Expect = 0.78 Identities = 24/72 (33%), Positives = 28/72 (38%), Gaps = 2/72 (2%) Query: 5 SYRQSSATSSFGGLGGGSVRFGPGVAFRAPSIHGGS--GGRGVSVSSARFVSSSSSGAYG 62 SY + S S G GGG G G + GGS GG G S S G + Sbjct: 484 SYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHS 543 Query: 63 GGYGGVLTASDG 74 GG GG + G Sbjct: 544 GGSGGGHSGGSG 555 Score = 32.0 bits (71), Expect = 1.0 Identities = 24/65 (36%), Positives = 27/65 (41%), Gaps = 4/65 (6%) Query: 3 SYSYRQSSATSSFGGLGGGS-VRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAY 61 +Y S S GG GGGS R G G + S GG G +S S G Y Sbjct: 557 NYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEE---ASGSGGGY 613 Query: 62 GGGYG 66 GGG G Sbjct: 614 GGGSG 618 Score = 30.8 bits (68), Expect = 2.3 Identities = 18/51 (35%), Positives = 22/51 (43%), Gaps = 1/51 (1%) Query: 16 GGLGGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAYGGGYG 66 GG GG +G G + +GG GG G S G+YGGG G Sbjct: 476 GGRGGSGGSYGRGSRGGSGGSYGG-GGSGGGYGGGSGSRGGSGGSYGGGSG 525 Score = 29.6 bits (65), Expect = 5.0 Identities = 25/76 (32%), Positives = 28/76 (36%), Gaps = 4/76 (5%) Query: 6 YRQSSATSSFGGLGGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAYGGGY 65 Y S GG GGG G G + S GG G G S S S G G+ Sbjct: 534 YGGGSGGGHSGGSGGGHSG-GSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGF 592 Query: 66 GGVLTASDGLLAGNEK 81 GG S G G E+ Sbjct: 593 GG---ESGGSYGGGEE 605 Score = 29.3 bits (64), Expect = 6.6 Identities = 18/46 (39%), Positives = 25/46 (54%), Gaps = 1/46 (2%) Query: 38 GGSGGRGV-SVSSARFVSSSSSGAYGGGYGGVLTASDGLLAGNEKL 82 GG GG G+ S S R S S + GGG GG ++S G G+ ++ Sbjct: 15 GGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRV 60 >gi|31559829 keratin 25 [Homo sapiens] Length = 450 Score = 369 bits (946), Expect = e-102 Identities = 201/377 (53%), Positives = 259/377 (68%), Gaps = 14/377 (3%) Query: 18 LGGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAYGGGY--GGVLTASDGL 75 L GG FG G + G G G SSA F SSS G GGG G GL Sbjct: 23 LYGGGTSFGTGNSC-------GISGIGSGFSSA-FGGSSSGGNTGGGNPCAGFTVNERGL 74 Query: 76 LAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPGPSR----DYSHYY 131 L+GNEK+TMQNLNDRLASYLD V ALE AN +LE KI+ WY+K GPG R DYS Y+ Sbjct: 75 LSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSRYF 134 Query: 132 TTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLD 191 I DL+++I+ +T N+ VLQIDNARL ADDFR K+E E AL SVEAD+NGLRRVLD Sbjct: 135 PIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRRVLD 194 Query: 192 ELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKILSD 251 E+TL RTDLE+Q E L EE+ YLKKNH+EE+ L+ GG V+VE+++APG DL +L++ Sbjct: 195 EITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTVLLNN 254 Query: 252 MRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQ 311 MR++YE +AEQNR+DAEAWF ++ L ++++ +R+E+T+++RTLQ LEIELQ Sbjct: 255 MRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLEIELQ 314 Query: 312 SQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKS 371 S L+ K +LE +L ETE+ + AQLA IQA I +E QL VR ++E Q EY++L+DIK Sbjct: 315 SLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDIKL 374 Query: 372 RLEQEIATYRSLLEGQE 388 LE+EI TY L+ G + Sbjct: 375 HLEKEIETYCLLIGGDD 391 >gi|116488398 keratin 32 [Homo sapiens] Length = 448 Score = 363 bits (933), Expect = e-100 Identities = 192/357 (53%), Positives = 257/357 (71%), Gaps = 2/357 (0%) Query: 34 PSIHGGSGGRGVSVSSARFVSSSSSGAYG--GGYGGVLTASDGLLAGNEKLTMQNLNDRL 91 PS+ + R S S ++SSS A G G G S+G GNEK TMQ LNDRL Sbjct: 48 PSVCLPTTFRPASCLSKTYLSSSCQAASGISGSMGPGSWYSEGAFNGNEKETMQFLNDRL 107 Query: 92 ASYLDKVRALEAANGELEVKIRDWYQKQGPGPSRDYSHYYTTIQDLRDKILGATIENSRI 151 ASYL +VR LE N ELE +I++ Q + DY ++ TI++L+ KIL EN+R+ Sbjct: 108 ASYLTRVRQLEQENAELESRIQEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARM 167 Query: 152 VLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEEL 211 V+ IDNA+LAADDFR K+E E A+R VEADINGLRR+LD+LTL + DLE Q+E LKEEL Sbjct: 168 VVNIDNAKLAADDFRAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEEL 227 Query: 212 AYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQNRKDAEAWF 271 LKKNHEEE+ +LR Q+G ++++EVD+AP DL ++L +MR QYE M E NR+D E WF Sbjct: 228 MCLKKNHEEEVGSLRCQLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWF 287 Query: 272 TSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQSQLSMKAALEDTLAETEARF 331 + EELN++VA +EQLQ +S++ DLRRT+ LEIELQ+Q S++ +LE+TL E+EAR+ Sbjct: 288 NMQMEELNQQVATSSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARY 347 Query: 332 GAQLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSRLEQEIATYRSLLEGQE 388 +QLA +Q +I+ +EAQL ++RAD ERQNQEYQ L+D+++RLE EI TYRSLLE ++ Sbjct: 348 SSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENED 404 >gi|14917115 keratin 31 [Homo sapiens] Length = 416 Score = 360 bits (925), Expect = e-99 Identities = 179/316 (56%), Positives = 249/316 (78%) Query: 73 DGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPGPSRDYSHYYT 132 +G G+EK TMQ LNDRLASYL+KVR LE N ELE IR+ Q+Q P Y Y+ Sbjct: 49 EGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFK 108 Query: 133 TIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDE 192 TI++L+ KIL EN+R+V+QIDNA+LAADDFRTK++TE +LR VE+DINGLRR+LDE Sbjct: 109 TIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDE 168 Query: 193 LTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKILSDM 252 LTL ++DLE Q+E LKEEL LK NHE+E++TLR Q+G +++VEVD+AP DL ++L++ Sbjct: 169 LTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNET 228 Query: 253 RSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQS 312 RSQYE + E NR++ E WFT++TEELN++V +EQLQ ++E+ +LRRT+ LEIELQ+ Sbjct: 229 RSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQA 288 Query: 313 QLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSR 372 Q +++ +LE+TL E+EAR+ +QL+ +Q+LI+ +E+QL ++R+D ERQNQEYQ L+D+++R Sbjct: 289 QHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRAR 348 Query: 373 LEQEIATYRSLLEGQE 388 LE EI TYRSLLE ++ Sbjct: 349 LECEINTYRSLLESED 364 >gi|14917117 keratin 33A [Homo sapiens] Length = 404 Score = 360 bits (924), Expect = 1e-99 Identities = 179/316 (56%), Positives = 249/316 (78%) Query: 73 DGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPGPSRDYSHYYT 132 +G G+EK TMQ LNDRLASYL+KVR LE N ELE IR+ Q+Q P Y Y+ Sbjct: 49 EGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFK 108 Query: 133 TIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDE 192 TI++L+ KIL + EN+R+V+QIDNA+LA+DDFRTK+ETE +LR VE+DINGLRR+LDE Sbjct: 109 TIEELQQKILCSKSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDE 168 Query: 193 LTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKILSDM 252 LTL R+DLE Q+E LKEEL LK+NHE+E++TLR Q+G +++VEVD+AP DL ++L++ Sbjct: 169 LTLCRSDLEAQVESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNET 228 Query: 253 RSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQS 312 RSQYE + E NR++ E WF ++TEELN++V +EQLQ ++E+ +LRRT+ LEIELQ+ Sbjct: 229 RSQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQA 288 Query: 313 QLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSR 372 Q +++ +LE+TL E+EAR+ +QL+ +Q LI+ +E+QL ++R+D ERQNQEYQ L+D+++R Sbjct: 289 QHNLRDSLENTLTESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRAR 348 Query: 373 LEQEIATYRSLLEGQE 388 LE EI TYRSLLE ++ Sbjct: 349 LECEINTYRSLLESED 364 >gi|10337581 type I hair keratin 3B [Homo sapiens] Length = 404 Score = 359 bits (922), Expect = 2e-99 Identities = 178/316 (56%), Positives = 250/316 (79%) Query: 73 DGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPGPSRDYSHYYT 132 +G G+EK TMQ LNDRLASYL+KVR LE N ELE IR+ Q+Q P Y Y+ Sbjct: 49 EGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFK 108 Query: 133 TIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDE 192 TI++L+ KIL + EN+R+V+QIDNA+LAADDFRTK++TEQ+LR VE+DIN LRR+LDE Sbjct: 109 TIEELQQKILCSKSENARLVVQIDNAKLAADDFRTKYQTEQSLRQLVESDINSLRRILDE 168 Query: 193 LTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKILSDM 252 LTL R+DLE Q+E LKEEL LK+NHE+E++TLR Q+G +++VEVD+AP DL ++L++ Sbjct: 169 LTLCRSDLEAQMESLKEELLSLKQNHEQEVNTLRCQLGDRLNVEVDAAPAVDLNQVLNET 228 Query: 253 RSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQS 312 R+QYE + E NR++ E WF ++TEELN++V +EQLQ ++E+ +LRRT+ LEIELQ+ Sbjct: 229 RNQYEALVETNRREVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQA 288 Query: 313 QLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSR 372 Q +++ +LE+TL E+EAR+ +QL+ +Q+LI+ +E+QL ++R+D ERQNQEYQ L+D+++R Sbjct: 289 QHNLRYSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRAR 348 Query: 373 LEQEIATYRSLLEGQE 388 LE EI TYRSLLE ++ Sbjct: 349 LECEINTYRSLLESED 364 >gi|14917119 keratin 34 [Homo sapiens] Length = 436 Score = 355 bits (911), Expect = 4e-98 Identities = 174/316 (55%), Positives = 248/316 (78%) Query: 73 DGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPGPSRDYSHYYT 132 +G G+EK TMQ LNDRLASYL+KVR LE N ELE I++ Q+Q P Y Y+ Sbjct: 91 EGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELEKLIQERSQQQEPLLCPSYQSYFK 150 Query: 133 TIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDE 192 TI++L+ KIL A EN+R+V+ IDNA+LA+DDFR+K++TEQ+LR+ VE+DIN +RR+LDE Sbjct: 151 TIEELQQKILCAKAENARLVVNIDNAKLASDDFRSKYQTEQSLRLLVESDINSIRRILDE 210 Query: 193 LTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKILSDM 252 LTL ++DLE Q+E L+EEL LKKNHEEE++TLR Q+G +++VEVD+AP DL ++L++ Sbjct: 211 LTLCKSDLESQVESLREELICLKKNHEEEVNTLRSQLGDRLNVEVDTAPTVDLNQVLNET 270 Query: 253 RSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQS 312 RSQYE + E NR++ E WF ++TEELN++V +EQLQ ++E+ +LRRT+ LEIELQ+ Sbjct: 271 RSQYEALVEINRREVEQWFATQTEELNKQVVSSSEQLQSCQAEIIELRRTVNALEIELQA 330 Query: 313 QLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSR 372 Q +++ +LE+TL E+EA + +QL+ +Q+LI+ +E+QL ++R D ERQNQEYQ L+D+++R Sbjct: 331 QHNLRDSLENTLTESEAHYSSQLSQVQSLITNVESQLAEIRCDLERQNQEYQVLLDVRAR 390 Query: 373 LEQEIATYRSLLEGQE 388 LE EI TYRSLLE ++ Sbjct: 391 LECEINTYRSLLESED 406 >gi|31559815 keratin 26 [Homo sapiens] Length = 468 Score = 348 bits (894), Expect = 4e-96 Identities = 196/394 (49%), Positives = 257/394 (65%), Gaps = 10/394 (2%) Query: 5 SYRQSSATSSFGGLGGGSVRFGPGVAFRAPSIHGGSGGRGV------SVSSARFVSSSSS 58 S+R S + G G G F A ++ GSG R +SS +S Sbjct: 2 SFRLSGGSRRICSRTGSGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNSGG 61 Query: 59 GAYGGGYGGVLTASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQK 118 G G G L LL+GNEK+TMQNLNDRLASYLD V ALE AN +LE KI+ Y+K Sbjct: 62 GLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRYEK 121 Query: 119 QGPGPSR----DYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQA 174 PG SR DYS Y++ I+DL+ +I ATI N+ IVLQ DNARL ADDFR K+E E A Sbjct: 122 CEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENELA 181 Query: 175 LRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVS 234 L SVEAD +GLRRVLDELTL TDLE+Q E L EEL YLKK+HEEE+ L+ GG V+ Sbjct: 182 LHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNVN 241 Query: 235 VEVDSAPGTDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRS 294 VE+++ PG DL +L++MR++YE +AEQNRKDAEAWF R+ L ++++ H +R+ Sbjct: 242 VEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAARN 301 Query: 295 EVTDLRRTLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRA 354 E+T+L+R LQ LEIELQS +++K + E +LAETE + QL IQ I +E QL +R Sbjct: 302 ELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRT 361 Query: 355 DSERQNQEYQRLMDIKSRLEQEIATYRSLLEGQE 388 ++E Q EY++L+D+K LE+EI Y +LL+G+E Sbjct: 362 ETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEE 395 >gi|40354195 keratin 18 [Homo sapiens] Length = 430 Score = 334 bits (857), Expect = 7e-92 Identities = 182/389 (46%), Positives = 266/389 (68%), Gaps = 12/389 (3%) Query: 8 QSSATSSFGGLGGGSV-RFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAYGGGYG 66 +S+ ++++ LG +G A S++ G+GG G +S VS S+S G G G Sbjct: 6 RSTFSTNYRSLGSVQAPSYGARPVSSAASVYAGAGGSGSRIS----VSRSTSFRGGMGSG 61 Query: 67 GVLTASDGLLAG-----NEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGP 121 G+ T G LAG NEK TMQ+LNDRLASYLD+VR+LE N LE KIR+ +K+GP Sbjct: 62 GLATGIAGGLAGMGGIQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGP 121 Query: 122 GPSRDYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEA 181 RD+SHY+ I+DLR +I T++N+RIVLQIDNARLAADDFR K+ETE A+R SVE Sbjct: 122 -QVRDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVEN 180 Query: 182 DINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQ-VSVEVDSA 240 DI+GLR+V+D+ + R LE +IE LKEEL ++KKNHEEE+ L+ Q+ ++VEVD+ Sbjct: 181 DIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAP 240 Query: 241 PGTDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLR 300 DLAKI++D+R+QY+ +A +NR++ + +++ + EE V + ++ + + +T+LR Sbjct: 241 KSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELR 300 Query: 301 RTLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQN 360 RT+Q LEI+L S ++KA+LE++L E EAR+ Q+ + ++ +E++L RA+ +RQ Sbjct: 301 RTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQA 360 Query: 361 QEYQRLMDIKSRLEQEIATYRSLLEGQED 389 QEY+ L++IK +LE EIATYR LLE ED Sbjct: 361 QEYEALLNIKVKLEAEIATYRRLLEDGED 389 >gi|4557888 keratin 18 [Homo sapiens] Length = 430 Score = 334 bits (857), Expect = 7e-92 Identities = 182/389 (46%), Positives = 266/389 (68%), Gaps = 12/389 (3%) Query: 8 QSSATSSFGGLGGGSV-RFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAYGGGYG 66 +S+ ++++ LG +G A S++ G+GG G +S VS S+S G G G Sbjct: 6 RSTFSTNYRSLGSVQAPSYGARPVSSAASVYAGAGGSGSRIS----VSRSTSFRGGMGSG 61 Query: 67 GVLTASDGLLAG-----NEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGP 121 G+ T G LAG NEK TMQ+LNDRLASYLD+VR+LE N LE KIR+ +K+GP Sbjct: 62 GLATGIAGGLAGMGGIQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGP 121 Query: 122 GPSRDYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEA 181 RD+SHY+ I+DLR +I T++N+RIVLQIDNARLAADDFR K+ETE A+R SVE Sbjct: 122 -QVRDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVEN 180 Query: 182 DINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQ-VSVEVDSA 240 DI+GLR+V+D+ + R LE +IE LKEEL ++KKNHEEE+ L+ Q+ ++VEVD+ Sbjct: 181 DIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAP 240 Query: 241 PGTDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLR 300 DLAKI++D+R+QY+ +A +NR++ + +++ + EE V + ++ + + +T+LR Sbjct: 241 KSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELR 300 Query: 301 RTLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQN 360 RT+Q LEI+L S ++KA+LE++L E EAR+ Q+ + ++ +E++L RA+ +RQ Sbjct: 301 RTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQA 360 Query: 361 QEYQRLMDIKSRLEQEIATYRSLLEGQED 389 QEY+ L++IK +LE EIATYR LLE ED Sbjct: 361 QEYEALLNIKVKLEAEIATYRRLLEDGED 389 >gi|125490370 type I hair keratin KA36 [Homo sapiens] Length = 431 Score = 326 bits (836), Expect = 2e-89 Identities = 165/323 (51%), Positives = 229/323 (70%) Query: 66 GGVLTASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPGPSR 125 G DG+ NEK TMQ LNDRLASYL+KVR+LE N ELE +I++ ++ P Sbjct: 75 GNCAWCEDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPMVCP 134 Query: 126 DYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADING 185 DY Y+ TI+DL+ KIL ENSR+ +Q+DN +LA DDF++K+E+E +LR +EADI+ Sbjct: 135 DYQRYFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISS 194 Query: 186 LRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDL 245 L +L+ELTL ++DLE +E LKE+L LKKNHEEE++ LR Q+G ++SVE+D+AP DL Sbjct: 195 LHGILEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDL 254 Query: 246 AKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQG 305 ++L +MR Q E + NR++AE W +TEELN++ EQLQ + E+ +L+RT Sbjct: 255 NRVLDEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASA 314 Query: 306 LEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQR 365 LEIELQ+Q S+ +LE T+AETEA++ +QLA IQ LI +E QL ++R D ERQNQEYQ Sbjct: 315 LEIELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQV 374 Query: 366 LMDIKSRLEQEIATYRSLLEGQE 388 L+D+K+RLE EI TY LL+ ++ Sbjct: 375 LLDVKARLEGEINTYWGLLDSED 397 >gi|27894339 keratin 23 [Homo sapiens] Length = 422 Score = 320 bits (819), Expect = 2e-87 Identities = 169/398 (42%), Positives = 257/398 (64%), Gaps = 10/398 (2%) Query: 2 TSYSYRQSSATSSFGGLGGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSSGAY 61 + +S+ Q+ + +SF G GGG R P RAP++HGG+GG +S+S G++ Sbjct: 3 SGHSFSQTPS-ASFHGAGGGWGR--PRSFPRAPTVHGGAGGARISLSFTTRSCPPPGGSW 59 Query: 62 GGGYGGVLTASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGP 121 G G S LL GN K TMQNLNDRLASYL+KVRALE AN +LE +I W+Q++ P Sbjct: 60 GSG------RSSPLLGGNGKATMQNLNDRLASYLEKVRALEEANMKLESRILKWHQQRDP 113 Query: 122 GPSRDYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEA 181 G +DYS Y I L+++I+ + N++I+L IDNAR+A DDF K+E E + + +E Sbjct: 114 GSKKDYSQYEENITHLQEQIVDGKMTNAQIILLIDNARMAVDDFNLKYENEHSFKKDLEI 173 Query: 182 DINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAP 241 ++ GLRR LD LT+ TDLE ++EG+++EL +KK+HE+E+ V+V+VD+ P Sbjct: 174 EVEGLRRTLDNLTIVTTDLEQEVEGMRKELILMKKHHEQEMEKHHVPSDFNVNVKVDTGP 233 Query: 242 GTDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRR 301 DL K+L DMR +YE++ ++ +D + W+ ++ +++E A +Q + ++ +L+R Sbjct: 234 REDLIKVLEDMRQEYELIIKKKHRDLDTWYKEQSAAMSQEAAS-PATVQSRQGDIHELKR 292 Query: 302 TLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQ 361 T Q LEI+LQ+Q S K+ALE+ L+ET++R+ +L +Q +IS E +L +R + ERQN Sbjct: 293 TFQALEIDLQTQYSTKSALENMLSETQSRYSCKLQDMQEIISHYEEELTQLRHELERQNN 352 Query: 362 EYQRLMDIKSRLEQEIATYRSLLEGQEDHYNNLSASKV 399 EYQ L+ IK+ LE+EI TYR LLEG+ + S S + Sbjct: 353 EYQVLLGIKTHLEKEITTYRRLLEGESEGTREESKSSM 390 >gi|148277620 type I hair keratin KA35 [Homo sapiens] Length = 491 Score = 317 bits (811), Expect = 2e-86 Identities = 164/310 (52%), Positives = 221/310 (71%) Query: 79 NEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPGPSRDYSHYYTTIQDLR 138 NEK TMQ LN+RLA+YL KVR LE N ELE KI++ K+ P DY YYTTI++L+ Sbjct: 95 NEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCPDYLSYYTTIEELQ 154 Query: 139 DKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTLART 198 KIL ENSR+V QIDN +L ADD R K+E E +LR VE+D NGL+++L+ LTL + Sbjct: 155 QKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLKQILNVLTLGKA 214 Query: 199 DLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKILSDMRSQYEV 258 DLE Q++ LKEEL LK NH+EEI++L+ Q+G ++ +EV +AP DL ++L +MR QYE Sbjct: 215 DLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQVLQEMRCQYEP 274 Query: 259 MAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQSQLSMKA 318 + E NRKD E WF ++ EELN++V ++Q Q + E+ +LRR++ LE+ELQ+Q M+ Sbjct: 275 IMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLEVELQAQHRMRD 334 Query: 319 ALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSRLEQEIA 378 + E L ETEAR+ A L IQ+LI +EAQL ++R ERQNQEY+ L+D+KSRLE EI Sbjct: 335 SQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILLDVKSRLECEIT 394 Query: 379 TYRSLLEGQE 388 TYRSLLE + Sbjct: 395 TYRSLLESSD 404 >gi|15431318 keratin 38 [Homo sapiens] Length = 456 Score = 311 bits (798), Expect = 5e-85 Identities = 161/326 (49%), Positives = 229/326 (70%), Gaps = 6/326 (1%) Query: 63 GGYGGVLTASDGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPG 122 G YG + L G+EK TMQ LNDRLA+YL+KVR LE N ELE + + + Sbjct: 93 GAYG------ENTLNGHEKETMQFLNDRLANYLEKVRQLEQENAELEATLLERSKCHEST 146 Query: 123 PSRDYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEAD 182 DY Y+ TI++L+ KIL + EN+R+++QIDNA+LAADDFR K E+E++LR VEAD Sbjct: 147 VCPDYQSYFHTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLRQLVEAD 206 Query: 183 INGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPG 242 G +++LD+ TLA+ DLE Q E LKEE LK NHE+E+ LR Q+G ++ +E+D P Sbjct: 207 KCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKLRIELDIEPT 266 Query: 243 TDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRT 302 DL ++L +MR+QYE M E NR+D E WF +++E ++ + +E+LQ +SE+ +LR T Sbjct: 267 IDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDMSCSEELQCCQSEILELRCT 326 Query: 303 LQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQE 362 + LE+E Q+Q ++K L+++L E E RFG +LA +Q+LIS +E QL ++RAD ERQNQE Sbjct: 327 VNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLISNVEEQLSEIRADLERQNQE 386 Query: 363 YQRLMDIKSRLEQEIATYRSLLEGQE 388 YQ L+D+K+RLE EIATYR+LLE ++ Sbjct: 387 YQVLLDVKTRLENEIATYRNLLESED 412 >gi|55770882 keratin 37 [Homo sapiens] Length = 449 Score = 305 bits (780), Expect = 6e-83 Identities = 154/313 (49%), Positives = 222/313 (70%) Query: 76 LAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPGPSRDYSHYYTTIQ 135 L G+EK TM+ LNDRLA+YL+KVR LE N ELE + + + DY Y+ TI+ Sbjct: 100 LNGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLERSKCHESTVCPDYQSYFRTIE 159 Query: 136 DLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTL 195 +L+ KIL + EN+R+++QIDNA+LAADDFR K E+E++L VEAD G +++LD+ TL Sbjct: 160 ELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLVEADKCGTQKLLDDATL 219 Query: 196 ARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKILSDMRSQ 255 A+ DLE Q E LKEE LK NHE+E+ LR Q+G + +E+D P DL ++L +MR+Q Sbjct: 220 AKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRIELDIEPTIDLNRVLGEMRAQ 279 Query: 256 YEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQSQLS 315 YE M E N +D E WF +++E ++ + +E+LQ +SE+ +LR T+ LE+E Q+Q + Sbjct: 280 YEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILELRCTVNALEVERQAQHT 339 Query: 316 MKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSRLEQ 375 +K L+++L E E R+G +LA +Q+LIS +E QL ++RAD ERQNQEYQ L+D+K+RLE Sbjct: 340 LKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQNQEYQVLLDVKARLEN 399 Query: 376 EIATYRSLLEGQE 388 EIATYR+LLE ++ Sbjct: 400 EIATYRNLLESED 412 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.129 0.347 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,910,337 Number of Sequences: 37866 Number of extensions: 550097 Number of successful extensions: 4618 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 204 Number of HSP's successfully gapped in prelim test: 439 Number of HSP's that attempted gapping in prelim test: 2792 Number of HSP's gapped (non-prelim): 1566 length of query: 400 length of database: 18,247,518 effective HSP length: 104 effective length of query: 296 effective length of database: 14,309,454 effective search space: 4235598384 effective search space used: 4235598384 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.