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Search of human proteins with 241982712
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|241982712 TBP-interacting protein isoform 1 [Homo sapiens]
(1236 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|241982712 TBP-interacting protein isoform 1 [Homo sapiens] 2400 0.0
gi|112420977 TBP-interacting protein isoform 2 [Homo sapiens] 2032 0.0
gi|21361794 TIP120 protein [Homo sapiens] 1545 0.0
gi|62460637 importin 4 [Homo sapiens] 72 3e-12
gi|4826730 FK506 binding protein 12-rapamycin associated protein... 50 1e-05
gi|54607053 GCN1 general control of amino-acid synthesis 1-like ... 42 0.004
gi|214010175 CLIP-associating protein 1 isoform 3 [Homo sapiens] 42 0.005
gi|214010173 CLIP-associating protein 1 isoform 2 [Homo sapiens] 42 0.005
gi|31563537 CLIP-associating protein 1 isoform 1 [Homo sapiens] 42 0.005
gi|57863301 CLIP-associating protein 2 [Homo sapiens] 40 0.011
gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding pro... 40 0.018
gi|32455246 beta isoform of regulatory subunit A, protein phosph... 39 0.040
gi|32455244 beta isoform of regulatory subunit A, protein phosph... 39 0.040
gi|21361399 alpha isoform of regulatory subunit A, protein phosp... 37 0.089
gi|150456415 HEAT repeat containing 5A [Homo sapiens] 37 0.089
gi|120431745 huntingtin-associated protein 1 isoform 4 [Homo sap... 37 0.12
gi|120431743 huntingtin-associated protein 1 isoform 3 [Homo sap... 37 0.12
gi|120431738 huntingtin-associated protein 1 isoform 2 [Homo sap... 37 0.12
gi|109134349 coatomer protein complex, subunit gamma 2 [Homo sap... 36 0.26
gi|23510381 transportin 1 isoform 2 [Homo sapiens] 35 0.34
gi|133925811 transportin 1 isoform 1 [Homo sapiens] 35 0.34
gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens] 35 0.34
gi|94421471 ring finger protein 17 [Homo sapiens] 35 0.34
gi|158631177 homeodomain leucine zipper protein [Homo sapiens] 35 0.34
gi|55956788 nucleolin [Homo sapiens] 35 0.44
gi|239749996 PREDICTED: similar to hCG1991922 [Homo sapiens] 35 0.44
gi|216548152 RNA pseudouridylate synthase domain containing 3 is... 35 0.44
gi|216548145 RNA pseudouridylate synthase domain containing 3 is... 35 0.44
gi|11559929 coatomer protein complex, subunit gamma 1 [Homo sapi... 35 0.44
gi|239751555 PREDICTED: functional smad suppressing element 18 [... 35 0.58
>gi|241982712 TBP-interacting protein isoform 1 [Homo sapiens]
Length = 1236
Score = 2400 bits (6220), Expect = 0.0
Identities = 1236/1236 (100%), Positives = 1236/1236 (100%)
Query: 1 MSTAAFHISSLLEKMTSSDKDFRFMATSDLMSELQKDSIQLDEDSERKVVKMLLRLLEDK 60
MSTAAFHISSLLEKMTSSDKDFRFMATSDLMSELQKDSIQLDEDSERKVVKMLLRLLEDK
Sbjct: 1 MSTAAFHISSLLEKMTSSDKDFRFMATSDLMSELQKDSIQLDEDSERKVVKMLLRLLEDK 60
Query: 61 NGEVQNLAVKCLGPLVVKVKEYQVETIVDTLCTNMRSDKEQLRDIAGIGLKTVLSELPPA 120
NGEVQNLAVKCLGPLVVKVKEYQVETIVDTLCTNMRSDKEQLRDIAGIGLKTVLSELPPA
Sbjct: 61 NGEVQNLAVKCLGPLVVKVKEYQVETIVDTLCTNMRSDKEQLRDIAGIGLKTVLSELPPA 120
Query: 121 ATGSGLATNVCRKITGQLTSAIAQQEDVAVQLEALDILSDMLSRLGVPLGAFHASLLHCL 180
ATGSGLATNVCRKITGQLTSAIAQQEDVAVQLEALDILSDMLSRLGVPLGAFHASLLHCL
Sbjct: 121 ATGSGLATNVCRKITGQLTSAIAQQEDVAVQLEALDILSDMLSRLGVPLGAFHASLLHCL 180
Query: 181 LPQLSSPRLAVRKRAVGALGHLAAACSTDLFVELADHLLDRLPGPRVPTSPTAIRTLIQC 240
LPQLSSPRLAVRKRAVGALGHLAAACSTDLFVELADHLLDRLPGPRVPTSPTAIRTLIQC
Sbjct: 181 LPQLSSPRLAVRKRAVGALGHLAAACSTDLFVELADHLLDRLPGPRVPTSPTAIRTLIQC 240
Query: 241 LGSVGRQAGHRLGAHLDRLVPLVEDFCNLDDDELRESCLQAFEAFLRKCPKEMGPHVPNV 300
LGSVGRQAGHRLGAHLDRLVPLVEDFCNLDDDELRESCLQAFEAFLRKCPKEMGPHVPNV
Sbjct: 241 LGSVGRQAGHRLGAHLDRLVPLVEDFCNLDDDELRESCLQAFEAFLRKCPKEMGPHVPNV 300
Query: 301 TSLCLQYIKHDPNYNYDSDEDEEQMETEDSEFSEQESEDEYSDDDDMSWKVRRAAAKCIA 360
TSLCLQYIKHDPNYNYDSDEDEEQMETEDSEFSEQESEDEYSDDDDMSWKVRRAAAKCIA
Sbjct: 301 TSLCLQYIKHDPNYNYDSDEDEEQMETEDSEFSEQESEDEYSDDDDMSWKVRRAAAKCIA 360
Query: 361 ALISSRPDLLPDFHCTLAPVLIRRFKEREENVKADVFTAYIVLLRQTQPPKGWLEAMEEP 420
ALISSRPDLLPDFHCTLAPVLIRRFKEREENVKADVFTAYIVLLRQTQPPKGWLEAMEEP
Sbjct: 361 ALISSRPDLLPDFHCTLAPVLIRRFKEREENVKADVFTAYIVLLRQTQPPKGWLEAMEEP 420
Query: 421 TQTGSNLHMLRGQVPLVVKALQRQLKDRSVRARQGCFSLLTELAGVLPGSLAEHMPVLVS 480
TQTGSNLHMLRGQVPLVVKALQRQLKDRSVRARQGCFSLLTELAGVLPGSLAEHMPVLVS
Sbjct: 421 TQTGSNLHMLRGQVPLVVKALQRQLKDRSVRARQGCFSLLTELAGVLPGSLAEHMPVLVS 480
Query: 481 GIIFSLADRSSSSTIRMDALAFLQGLLGTEPAEAFHPHLPILLPPVMACVADSFYKIAAE 540
GIIFSLADRSSSSTIRMDALAFLQGLLGTEPAEAFHPHLPILLPPVMACVADSFYKIAAE
Sbjct: 481 GIIFSLADRSSSSTIRMDALAFLQGLLGTEPAEAFHPHLPILLPPVMACVADSFYKIAAE 540
Query: 541 ALVVLQELVRALWPLHRPRMLDPEPYVGEMSAVTLARLRATDLDQEVKERAISCMGHLVG 600
ALVVLQELVRALWPLHRPRMLDPEPYVGEMSAVTLARLRATDLDQEVKERAISCMGHLVG
Sbjct: 541 ALVVLQELVRALWPLHRPRMLDPEPYVGEMSAVTLARLRATDLDQEVKERAISCMGHLVG 600
Query: 601 HLGDRLGDDLEPTLLLLLDRLRNEITRLPAIKALTLVAVSPLQLDLQPILAEALHILASF 660
HLGDRLGDDLEPTLLLLLDRLRNEITRLPAIKALTLVAVSPLQLDLQPILAEALHILASF
Sbjct: 601 HLGDRLGDDLEPTLLLLLDRLRNEITRLPAIKALTLVAVSPLQLDLQPILAEALHILASF 660
Query: 661 LRKNQRALRLATLAALDALAQSQGLSLPPSAVQAVLAELPALVNESDMHVAQLAVDFLAT 720
LRKNQRALRLATLAALDALAQSQGLSLPPSAVQAVLAELPALVNESDMHVAQLAVDFLAT
Sbjct: 661 LRKNQRALRLATLAALDALAQSQGLSLPPSAVQAVLAELPALVNESDMHVAQLAVDFLAT 720
Query: 721 VTQAQPASLVEVSGPVLSELLRLLRSPLLPAGVLAAAEGFLQALVGTRPPCVDYAKLISL 780
VTQAQPASLVEVSGPVLSELLRLLRSPLLPAGVLAAAEGFLQALVGTRPPCVDYAKLISL
Sbjct: 721 VTQAQPASLVEVSGPVLSELLRLLRSPLLPAGVLAAAEGFLQALVGTRPPCVDYAKLISL 780
Query: 781 LTAPVYEQAVDGGPGLHKQVFHSLARCVAALSAACPQEAASTASRLVCDARSPHSSTGVK 840
LTAPVYEQAVDGGPGLHKQVFHSLARCVAALSAACPQEAASTASRLVCDARSPHSSTGVK
Sbjct: 781 LTAPVYEQAVDGGPGLHKQVFHSLARCVAALSAACPQEAASTASRLVCDARSPHSSTGVK 840
Query: 841 VLAFLSLAEVGQVAGPGHQRELKAVLLEALGSPSEDVRAAASYALGRVGAGSLPDFLPFL 900
VLAFLSLAEVGQVAGPGHQRELKAVLLEALGSPSEDVRAAASYALGRVGAGSLPDFLPFL
Sbjct: 841 VLAFLSLAEVGQVAGPGHQRELKAVLLEALGSPSEDVRAAASYALGRVGAGSLPDFLPFL 900
Query: 901 LEQIEAEPRRQYLLLHSLREALGAAQPDSLKPYAEDIWALLFQRCEGAEEGTRGVVAECI 960
LEQIEAEPRRQYLLLHSLREALGAAQPDSLKPYAEDIWALLFQRCEGAEEGTRGVVAECI
Sbjct: 901 LEQIEAEPRRQYLLLHSLREALGAAQPDSLKPYAEDIWALLFQRCEGAEEGTRGVVAECI 960
Query: 961 GKLVLVNPSFLLPRLRKQLAAGRPHTRSTVITAVKFLISDQPHPIDPLLKSFIGEFMESL 1020
GKLVLVNPSFLLPRLRKQLAAGRPHTRSTVITAVKFLISDQPHPIDPLLKSFIGEFMESL
Sbjct: 961 GKLVLVNPSFLLPRLRKQLAAGRPHTRSTVITAVKFLISDQPHPIDPLLKSFIGEFMESL 1020
Query: 1021 QDPDLNVRRATLAFFNSAVHNKPSLVRDLLDDILPLLYQETKIRRDLIREVEMGPFKHTV 1080
QDPDLNVRRATLAFFNSAVHNKPSLVRDLLDDILPLLYQETKIRRDLIREVEMGPFKHTV
Sbjct: 1021 QDPDLNVRRATLAFFNSAVHNKPSLVRDLLDDILPLLYQETKIRRDLIREVEMGPFKHTV 1080
Query: 1081 DDGLDVRKAAFECMYSLLESCLGQLDICEFLNHVEDGLKDHYDIRMLTFIMVARLATLCP 1140
DDGLDVRKAAFECMYSLLESCLGQLDICEFLNHVEDGLKDHYDIRMLTFIMVARLATLCP
Sbjct: 1081 DDGLDVRKAAFECMYSLLESCLGQLDICEFLNHVEDGLKDHYDIRMLTFIMVARLATLCP 1140
Query: 1141 APVLQRVDRLIEPLRATCTAKVKAGSVKQEFEKQDELKRSAMRAVAALLTIPEVGKSPIM 1200
APVLQRVDRLIEPLRATCTAKVKAGSVKQEFEKQDELKRSAMRAVAALLTIPEVGKSPIM
Sbjct: 1141 APVLQRVDRLIEPLRATCTAKVKAGSVKQEFEKQDELKRSAMRAVAALLTIPEVGKSPIM 1200
Query: 1201 ADFSSQIRSNPELAALFESIQKDSASAPSTDSMELS 1236
ADFSSQIRSNPELAALFESIQKDSASAPSTDSMELS
Sbjct: 1201 ADFSSQIRSNPELAALFESIQKDSASAPSTDSMELS 1236
>gi|112420977 TBP-interacting protein isoform 2 [Homo sapiens]
Length = 1119
Score = 2032 bits (5264), Expect = 0.0
Identities = 1048/1072 (97%), Positives = 1048/1072 (97%), Gaps = 24/1072 (2%)
Query: 165 LGVPLGAFHASLLHCLLPQLSSPRLAVRKRAVGALGHLAAACSTDLFVELADHLLDRLPG 224
LGVPLGAFHASLLHCLLPQLSSPRLAVRKRAVGALGHLAAACSTDLFVELADHLLDRLPG
Sbjct: 72 LGVPLGAFHASLLHCLLPQLSSPRLAVRKRAVGALGHLAAACSTDLFVELADHLLDRLPG 131
Query: 225 PRVPTSPTAIRTLIQCLGSVGRQAGHRLGAHLDRLVPLVEDFCNLDDDELRESCLQAFEA 284
PRVPTSPTAIRTLIQCLGSVGRQAGHRLGAHLDRLVPLVEDFCNLDDDELRESCLQAFEA
Sbjct: 132 PRVPTSPTAIRTLIQCLGSVGRQAGHRLGAHLDRLVPLVEDFCNLDDDELRESCLQAFEA 191
Query: 285 FLRKCPKEMGPHVPNVTSLCLQYIKHDPNYNYDSDEDEEQMETEDSEFSEQESEDEYSDD 344
FLRKCPKEMGPHVPNVTSLCLQYIKHDPNYNYDSDEDEEQMETEDSEFSEQESEDEYSDD
Sbjct: 192 FLRKCPKEMGPHVPNVTSLCLQYIKHDPNYNYDSDEDEEQMETEDSEFSEQESEDEYSDD 251
Query: 345 DDMSWKVRRAAAKCIAALISSRPDLLPDFHCTLAPVLIRRFKEREENVKADVFTAYIVLL 404
DDMSWKVRRAAAKCIAALISSRPDLLPDFHCTLAPVLIRRFKEREENVKADVFTAYIVLL
Sbjct: 252 DDMSWKVRRAAAKCIAALISSRPDLLPDFHCTLAPVLIRRFKEREENVKADVFTAYIVLL 311
Query: 405 RQTQPPKGWLEAMEEPTQTGSNLHMLRGQVPLVVKALQRQLKDRSVRARQGCFSLLTELA 464
RQTQPPKGWLEAMEEPTQTGSNLHMLRGQVPLVVKALQRQLKDRSVRARQGCFSLLTELA
Sbjct: 312 RQTQPPKGWLEAMEEPTQTGSNLHMLRGQVPLVVKALQRQLKDRSVRARQGCFSLLTELA 371
Query: 465 GVLPGSLAEHMPVLVSGIIFSLADRSSSSTIRMDALAFLQGLLGTEPAEAFHPHLPILLP 524
GVLPGSLAEHMPVLVSGIIFSLADRSSSSTIRMDALAFLQGLLGTEPAEAFHPHLPILLP
Sbjct: 372 GVLPGSLAEHMPVLVSGIIFSLADRSSSSTIRMDALAFLQGLLGTEPAEAFHPHLPILLP 431
Query: 525 PVMACVADSFYKIAAEALVVLQELVRALWPLHRPRMLDPEPYVGEMSAVTLARLRATDLD 584
PVMACVADSFYKIAAEALVVLQELVRALWPLHRPRMLDPEPYVGEMSAVTLARLRATDLD
Sbjct: 432 PVMACVADSFYKIAAEALVVLQELVRALWPLHRPRMLDPEPYVGEMSAVTLARLRATDLD 491
Query: 585 QEVKERAISCMGHLVGHLGDRLGDDLEPTLLLLLDRLRNEITRLPAIKALTLVAVSPLQL 644
QEVKERAISCMGHLVGHLGDRLGDDLEPTLLLLLDRLRNEITRLPAIKALTLVAVSPLQL
Sbjct: 492 QEVKERAISCMGHLVGHLGDRLGDDLEPTLLLLLDRLRNEITRLPAIKALTLVAVSPLQL 551
Query: 645 DLQPILAEALHILASFLRKNQRALRLATLAALDALAQSQGLSLPPSAVQAVLAELPALVN 704
DLQPILAEALHILASFLRKNQRALRLATLAALDALAQSQGLSLPPSAVQAVLAELPALVN
Sbjct: 552 DLQPILAEALHILASFLRKNQRALRLATLAALDALAQSQGLSLPPSAVQAVLAELPALVN 611
Query: 705 ESDMHVAQLAVDFLATVTQAQPASLVEVSGPVLSELLRLLRSPLLPAGVLAAAEGFLQAL 764
ESDMHVAQLAVDFLATVTQAQPASLVEVSGPVLSELLRLLRSPLLPAGVLAAAEGFLQAL
Sbjct: 612 ESDMHVAQLAVDFLATVTQAQPASLVEVSGPVLSELLRLLRSPLLPAGVLAAAEGFLQAL 671
Query: 765 VGTRPPCVDYAKLISLLTAPVYEQAVDGGPGLHKQVFHSLARCVAALSAACPQEAASTAS 824
VGTRPPCVDYAKLISLLTAPVYEQAVDGGPGLHKQVFHSLARCVAALSAACPQEAASTAS
Sbjct: 672 VGTRPPCVDYAKLISLLTAPVYEQAVDGGPGLHKQVFHSLARCVAALSAACPQEAASTAS 731
Query: 825 RLVCDARSPHSSTGVKVLAFLSLAEVGQVAGPGHQRELKAVLLEALGSPSEDVRAAASYA 884
RLVCDARSPHSSTGVKVLAFLSLAEVGQVAGPGHQRELKAVLLEALGSPSEDVRAAASYA
Sbjct: 732 RLVCDARSPHSSTGVKVLAFLSLAEVGQVAGPGHQRELKAVLLEALGSPSEDVRAAASYA 791
Query: 885 LGRVGAGSLPDFLPFLLEQIEAEPRRQYLLLHSLREALGAAQPDSLKPYAEDIWALLFQR 944
LGRVGAGSLPDFLPFLLEQIEAEPRRQYLLLHSLREALGAAQPDSLKPYAEDIWALLFQR
Sbjct: 792 LGRVGAGSLPDFLPFLLEQIEAEPRRQYLLLHSLREALGAAQPDSLKPYAEDIWALLFQR 851
Query: 945 CEGAEEGTRGVVAECIGKLVLVNPSFLLPRLRKQLAAGRPHTRSTVITAVKFLISDQPHP 1004
CEGAEEGTRGVVAECIGKLVLVNPSFLLPRLRKQLAAGRPHTRSTVITAVKFLISDQPHP
Sbjct: 852 CEGAEEGTRGVVAECIGKLVLVNPSFLLPRLRKQLAAGRPHTRSTVITAVKFLISDQPHP 911
Query: 1005 IDPLLKSFIGEFMESLQDPDLNVRRATLAFFNSAVHNKPSLVRDLLDDILPLLYQETKIR 1064
IDPLLKSFI AVHNKPSLVRDLLDDILPLLYQETKIR
Sbjct: 912 IDPLLKSFI------------------------AVHNKPSLVRDLLDDILPLLYQETKIR 947
Query: 1065 RDLIREVEMGPFKHTVDDGLDVRKAAFECMYSLLESCLGQLDICEFLNHVEDGLKDHYDI 1124
RDLIREVEMGPFKHTVDDGLDVRKAAFECMYSLLESCLGQLDICEFLNHVEDGLKDHYDI
Sbjct: 948 RDLIREVEMGPFKHTVDDGLDVRKAAFECMYSLLESCLGQLDICEFLNHVEDGLKDHYDI 1007
Query: 1125 RMLTFIMVARLATLCPAPVLQRVDRLIEPLRATCTAKVKAGSVKQEFEKQDELKRSAMRA 1184
RMLTFIMVARLATLCPAPVLQRVDRLIEPLRATCTAKVKAGSVKQEFEKQDELKRSAMRA
Sbjct: 1008 RMLTFIMVARLATLCPAPVLQRVDRLIEPLRATCTAKVKAGSVKQEFEKQDELKRSAMRA 1067
Query: 1185 VAALLTIPEVGKSPIMADFSSQIRSNPELAALFESIQKDSASAPSTDSMELS 1236
VAALLTIPEVGKSPIMADFSSQIRSNPELAALFESIQKDSASAPSTDSMELS
Sbjct: 1068 VAALLTIPEVGKSPIMADFSSQIRSNPELAALFESIQKDSASAPSTDSMELS 1119
Score = 137 bits (345), Expect = 6e-32
Identities = 72/73 (98%), Positives = 72/73 (98%)
Query: 1 MSTAAFHISSLLEKMTSSDKDFRFMATSDLMSELQKDSIQLDEDSERKVVKMLLRLLEDK 60
MSTAAFHISSLLEKMTSSDKDFRFMATSDLMSELQKDSIQLDEDSERKVVKMLLRLLEDK
Sbjct: 1 MSTAAFHISSLLEKMTSSDKDFRFMATSDLMSELQKDSIQLDEDSERKVVKMLLRLLEDK 60
Query: 61 NGEVQNLAVKCLG 73
NGEVQNLAVK LG
Sbjct: 61 NGEVQNLAVKWLG 73
>gi|21361794 TIP120 protein [Homo sapiens]
Length = 1230
Score = 1545 bits (4001), Expect = 0.0
Identities = 772/1237 (62%), Positives = 988/1237 (79%), Gaps = 8/1237 (0%)
Query: 1 MSTAAFHISSLLEKMTSSDKDFRFMATSDLMSELQKDSIQLDEDSERKVVKMLLRLLEDK 60
M++A++HIS+LLEKMTSSDKDFRFMAT+DLM+ELQKDSI+LD+DSERKVVKM+L+LLEDK
Sbjct: 1 MASASYHISNLLEKMTSSDKDFRFMATNDLMTELQKDSIKLDDDSERKVVKMILKLLEDK 60
Query: 61 NGEVQNLAVKCLGPLVVKVKEYQVETIVDTLCTNMRSDKEQLRDIAGIGLKTVLSELPPA 120
NGEVQNLAVKCLGPLV KVKEYQVETIVDTLCTNM SDKEQLRDI+ IGLKTV+ ELPPA
Sbjct: 61 NGEVQNLAVKCLGPLVSKVKEYQVETIVDTLCTNMLSDKEQLRDISSIGLKTVIGELPPA 120
Query: 121 ATGSGLATNVCRKITGQLTSAIAQQEDVAVQLEALDILSDMLSRLGVPLGAFHASLLHCL 180
++GS LA NVC+KITG+LTSAIA+QEDV+VQLEALDI++DMLSR G L FH S+L CL
Sbjct: 121 SSGSALAANVCKKITGRLTSAIAKQEDVSVQLEALDIMADMLSRQGGLLVNFHPSILTCL 180
Query: 181 LPQLSSPRLAVRKRAVGALGHLAAACSTDLFVELADHLLDRLPGPRVPTSPTAIRTLIQC 240
LPQL+SPRLAVRKR + ALGHL +C +FV+L +HLL L S + RT IQC
Sbjct: 181 LPQLTSPRLAVRKRTIIALGHLVMSCGNIVFVDLIEHLLSELSKN---DSMSTTRTYIQC 237
Query: 241 LGSVGRQAGHRLGAHLDRLVPLVEDFCNLDDDELRESCLQAFEAFLRKCPKEMGPHVPNV 300
+ ++ RQAGHR+G +L++++PLV FCN+DDDELRE C+QAFE+F+R+CPKE+ PHV +
Sbjct: 238 IAAISRQAGHRIGEYLEKIIPLVVKFCNVDDDELREYCIQAFESFVRRCPKEVYPHVSTI 297
Query: 301 TSLCLQYIKHDPNYNYDS-DEDEEQMETEDSEFSEQESEDEYSDDDDMSWKVRRAAAKCI 359
++CL+Y+ +DPNYNYD DEDE M+ + + +Q S+DEYSDDDDMSWKVRRAAAKC+
Sbjct: 298 INICLKYLTYDPNYNYDDEDEDENAMDADGGDDDDQGSDDEYSDDDDMSWKVRRAAAKCL 357
Query: 360 AALISSRPDLLPDFHCTLAPVLIRRFKEREENVKADVFTAYIVLLRQTQPPKGWLEAMEE 419
A++S+R ++LP+F+ T++P LI RFKEREENVKADVF AY+ LL+QT+P + WL +
Sbjct: 358 DAVVSTRHEMLPEFYKTVSPALISRFKEREENVKADVFHAYLSLLKQTRPVQSWLCDPDA 417
Query: 420 PTQTGSNLHMLRGQVPLVVKALQRQLKDRSVRARQGCFSLLTELAGVLPGSLAEHMPVLV 479
Q + L ML+ QVP +VKAL +Q+K++SV+ RQ CF++LTEL VLPG+L +H+PVLV
Sbjct: 418 MEQGETPLTMLQSQVPNIVKALHKQMKEKSVKTRQCCFNMLTELVNVLPGALTQHIPVLV 477
Query: 480 SGIIFSLADRSSSSTIRMDALAFLQGLLGTEPAEAFHPHLPILLPPVMACVADSFYKIAA 539
GIIFSL D+SSSS +++DAL+ L +L + FHPH+ L+PPV+ACV D FYKI +
Sbjct: 478 PGIIFSLNDKSSSSNLKIDALSCLYVILCNHSPQVFHPHVQALVPPVVACVGDPFYKITS 537
Query: 540 EALVVLQELVRALWPLHRPRMLDPEPYVGEMSAVTLARLRATDLDQEVKERAISCMGHLV 599
EAL+V Q+LV+ + PL +P D PY+ ++ T+ RL+A D+DQEVKERAISCMG ++
Sbjct: 538 EALLVTQQLVKVIRPLDQPSSFDATPYIKDLFTCTIKRLKAADIDQEVKERAISCMGQII 597
Query: 600 GHLGDRLGDDLEPTLLLLLDRLRNEITRLPAIKALTLVAVSPLQLDLQPILAEALHILAS 659
+LGD LG DL TL + L+RL+NEITRL +KALTL+A SPL++DL+P+L E + ILAS
Sbjct: 598 CNLGDNLGSDLPNTLQIFLERLKNEITRLTTVKALTLIAGSPLKIDLRPVLGEGVPILAS 657
Query: 660 FLRKNQRALRLATLAALDALAQSQGLSLPPSAVQAVLAELPALVNESDMHVAQLAVDFLA 719
FLRKNQRAL+L TL+ALD L ++ SL + + AVL ELP L++ESDMHV+Q+A+ FL
Sbjct: 658 FLRKNQRALKLGTLSALDILIKNYSDSLTAAMIDAVLDELPPLISESDMHVSQMAISFLT 717
Query: 720 TVTQAQPASLVEVSGPVLSELLRLLRSPLLPAGVLAAAEGFLQALVGTRPPCVDYAKLIS 779
T+ + P+SL ++SG +L+EL+ L+RSPLL G L+A F QALV T + Y L+
Sbjct: 718 TLAKVYPSSLSKISGSILNELIGLVRSPLLQGGALSAMLDFFQALVVTGTNNLGYMDLLR 777
Query: 780 LLTAPVYEQAVDGGPGLHKQVFHSLARCVAALSAACPQEAASTASRLVCDARSPHSSTGV 839
+LT PVY Q+ HKQ ++S+A+CVAAL+ ACP+E + + + D ++ S+ +
Sbjct: 778 MLTGPVYSQST---ALTHKQSYYSIAKCVAALTRACPKEGPAVVGQFIQDVKNSRSTDSI 834
Query: 840 KVLAFLSLAEVGQVAGPGHQRELKAVLLEALGSPSEDVRAAASYALGRVGAGSLPDFLPF 899
++LA LSL EVG Q ELK+V+LEA SPSE+V++AASYALG + G+LP++LPF
Sbjct: 835 RLLALLSLGEVGHHIDLSGQLELKSVILEAFSSPSEEVKSAASYALGSISVGNLPEYLPF 894
Query: 900 LLEQIEAEPRRQYLLLHSLREALGAAQPDSLKPYAEDIWALLFQRCEGAEEGTRGVVAEC 959
+L++I ++P+RQYLLLHSL+E + +A LKPY E+IWALL + CE AEEGTR VVAEC
Sbjct: 895 VLQEITSQPKRQYLLLHSLKEIISSASVVGLKPYVENIWALLLKHCECAEEGTRNVVAEC 954
Query: 960 IGKLVLVNPSFLLPRLRKQLAAGRPHTRSTVITAVKFLISDQPHPIDPLLKSFIGEFMES 1019
+GKL L++P LLPRL+ L +G + RS+V+TAVKF ISD P PIDPLLK+ IG+F+++
Sbjct: 955 LGKLTLIDPETLLPRLKGYLISGSSYARSSVVTAVKFTISDHPQPIDPLLKNCIGDFLKT 1014
Query: 1020 LQDPDLNVRRATLAFFNSAVHNKPSLVRDLLDDILPLLYQETKIRRDLIREVEMGPFKHT 1079
L+DPDLNVRR L FNSA HNKPSL+RDLLD +LP LY ETK+R++LIREVEMGPFKHT
Sbjct: 1015 LEDPDLNVRRVALVTFNSAAHNKPSLIRDLLDTVLPHLYNETKVRKELIREVEMGPFKHT 1074
Query: 1080 VDDGLDVRKAAFECMYSLLESCLGQLDICEFLNHVEDGLKDHYDIRMLTFIMVARLATLC 1139
VDDGLD+RKAAFECMY+LL+SCL +LDI EFLNHVEDGLKDHYDI+MLTF+M+ RL+TLC
Sbjct: 1075 VDDGLDIRKAAFECMYTLLDSCLDRLDIFEFLNHVEDGLKDHYDIKMLTFLMLVRLSTLC 1134
Query: 1140 PAPVLQRVDRLIEPLRATCTAKVKAGSVKQEFEKQDELKRSAMRAVAALLTIPEVGKSPI 1199
P+ VLQR+DRL+EPLRATCT KVKA SVKQEFEKQDELKRSAMRAVAALLTIPE KSP+
Sbjct: 1135 PSAVLQRLDRLVEPLRATCTTKVKANSVKQEFEKQDELKRSAMRAVAALLTIPEAEKSPL 1194
Query: 1200 MADFSSQIRSNPELAALFESIQKDSASAPSTDSMELS 1236
M++F SQI SNPELAA+FESIQKDS+S + +SM+ S
Sbjct: 1195 MSEFQSQISSNPELAAIFESIQKDSSST-NLESMDTS 1230
>gi|62460637 importin 4 [Homo sapiens]
Length = 1081
Score = 72.0 bits (175), Expect = 3e-12
Identities = 157/689 (22%), Positives = 257/689 (37%), Gaps = 124/689 (17%)
Query: 36 KDSIQLDEDSERKVVKMLLRLLEDKNGEVQNLAVKCLGPLVVKVKEYQVETIVDTLCTNM 95
+++++ + +RK ++L +L D G+ +++ + ++ +C +
Sbjct: 358 EEALRSESPYQRKAGLLVLAVLSDGAGD--------------HIRQRLLPPLLQIVCKGL 403
Query: 96 RSDKEQLRDIAGIGLKTVLSELPPAATGSGLATNVCRKITGQLTSA-IAQQEDVAVQLEA 154
+ +R+ A L L P S + V + L S + +A A
Sbjct: 404 EDPSQVVRNAALFALGQFSENLQPHI--SSYSREVMPLLLAYLKSVPLGHTHHLAKACYA 461
Query: 155 LDILSDMLSRLGVPLGAFHASLLHCLLPQL---SSPRLAVRKRAVGALGHLAAACSTDL- 210
L+ + + LG + + L+ C+L L SSPR ++ AV ALG +A A L
Sbjct: 462 LE---NFVENLGPKVQPYLPELMECMLQLLRNPSSPR--AKELAVSALGAIATAAQASLL 516
Query: 211 --FVELADHLLDRLPGPRVPTSPTAIRTLIQCLGSVGRQAGHRLGAHLDRLVPLVEDFCN 268
F + +HL + L R P I++L + LG + R G + + PL E+ C
Sbjct: 517 PYFPAIMEHLREFLLTGREDLQPVQIQSL-ETLGVLARAVG-------EPMRPLAEECCQ 568
Query: 269 L--------DDDELRESCLQAFEAFLRKCPKEMGPHVPNVTSLCLQYIKHD----PNYN- 315
L DD +LR F A + + PH+ +T+L L ++ P Y+
Sbjct: 569 LGLGLCDQVDDPDLRRCTYSLFAALSGLMGEGLAPHLEQITTLMLLSLRSTEGIVPQYDG 628
Query: 316 ----------YDSDEDEEQM-----ETEDSEFSEQESEDEYSDD-DDMSWKVRRAAAKCI 359
D +E+EE M E +DSE S E+ + D+ +D V +
Sbjct: 629 SSSFLLFDDESDGEEEEELMDEDVEEEDDSEISGYSVENAFFDEKEDTCAAVGEISVNTS 688
Query: 360 AALISSRPDLLPD-FHCTLAPVLIRRFKEREENVKADVFTAYIVLLRQTQPPKGWLEAME 418
A + + + F P L R E F + Q+ P
Sbjct: 689 VAFLPYMESVFEEVFKLLECPHLNVRKAAHE---ALGQFCCALHKACQSCP--------S 737
Query: 419 EPTQTGSNLHMLRGQVPLVVKALQRQLKDRSVRARQGCFSLLTELAGVL----------P 468
EP + R VP ++A+ R+ R RQ ++L L GVL P
Sbjct: 738 EPNTAALQAALAR-VVPSYMQAVNRE------RERQVVMAVLEALTGVLRSCGTLTLKPP 790
Query: 469 GSLAEHMPVLVSGIIFSLA--------DRSSSSTIRMDALAF------LQGLLGTEPAEA 514
G LAE VL + + A + DA+ + L ++
Sbjct: 791 GRLAELCGVLKAVLQRKTACQDTDEEEEEEDDDQAEYDAMLLEHAGEAIPALAAAAGGDS 850
Query: 515 FHPHLPILLPPVMACVADSFYKIAAEALVV--LQELVRALWPLHRPRMLDPEPYVGEMSA 572
F P L P++ C +A ++ V L E ++ L +V +
Sbjct: 851 FAPFFAGFL-PLLVCKTKQGCTVAEKSFAVGTLAETIQGLGAA-------SAQFVSRLLP 902
Query: 573 VTLARLRATDLDQEVKERAISCMGHLVGHLGDRLGDDLEPTLLL---LLDRLRNEITRLP 629
V L+ A + D EV+ AI MG L H G + L L LL R R++ R
Sbjct: 903 VLLS--TAQEADPEVRSNAIFGMGVLAEHGGHPAQEHFPKLLGLLFPLLARERHDRVRDN 960
Query: 630 AIKALT-LVAVSPLQLDLQPILAEALHIL 657
AL L+ SP + +LA LH L
Sbjct: 961 ICGALARLLMASPTRKPEPQVLAALLHAL 989
Score = 34.3 bits (77), Expect = 0.76
Identities = 58/253 (22%), Positives = 99/253 (39%), Gaps = 28/253 (11%)
Query: 603 GDRLGDDLEPTLLLLLDRLRNEITRLPAIKALTLVAVSPLQLDLQPILA----EALHILA 658
GD + L P LL ++ + + +++ ++ L A+ +LQP ++ E + +L
Sbjct: 384 GDHIRQRLLPPLLQIVCKGLEDPSQV--VRNAALFALGQFSENLQPHISSYSREVMPLLL 441
Query: 659 SFLRKNQ--RALRLATLA-ALDALAQSQGLSLPPSAVQAVLAELPALVNESDMHVAQLAV 715
++L+ LA AL+ ++ G + P + + L L N S +LAV
Sbjct: 442 AYLKSVPLGHTHHLAKACYALENFVENLGPKVQPYLPELMECMLQLLRNPSSPRAKELAV 501
Query: 716 DFLATVTQAQPASLVEVSGPVLSELLRLLRSPLLPAGVLAAAEGFLQALVGTRPPCVDYA 775
L + A ASL+ ++ L L L E + + A
Sbjct: 502 SALGAIATAAQASLLPYFPAIMEHLREFL---------LTGREDLQPVQIQSLETLGVLA 552
Query: 776 KLISLLTAPVYEQAVDGGPGLHKQVFH-SLARCVAALSAACPQEAASTASRLVCDARSPH 834
+ + P+ E+ G GL QV L RC +L AA S L+ + +PH
Sbjct: 553 RAVGEPMRPLAEECCQLGLGLCDQVDDPDLRRCTYSLFAA--------LSGLMGEGLAPH 604
Query: 835 SSTGVKVLAFLSL 847
+ L LSL
Sbjct: 605 LEQ-ITTLMLLSL 616
Score = 33.5 bits (75), Expect = 1.3
Identities = 61/253 (24%), Positives = 98/253 (38%), Gaps = 44/253 (17%)
Query: 815 CPQEAASTASRLVCDARSPHS-STGVKVLAFLSLAEVGQVAGPGHQRELKAVLLE----A 869
CPQ L + SP+ G+ VLA LS AG ++ L LL+
Sbjct: 350 CPQLMPMLEEAL--RSESPYQRKAGLLVLAVLS-----DGAGDHIRQRLLPPLLQIVCKG 402
Query: 870 LGSPSEDVRAAASYALGRVGAGSLP-------DFLPFLLEQIEAEPRRQYLLLHSLREAL 922
L PS+ VR AA +ALG+ P + +P LL +++ P H L +A
Sbjct: 403 LEDPSQVVRNAALFALGQFSENLQPHISSYSREVMPLLLAYLKSVPLGH---THHLAKAC 459
Query: 923 GAAQ------PDSLKPYAEDIWALLFQRCEG-AEEGTRGVVAECIGKLVLVNPSFLLP-- 973
A + ++PY ++ + Q + + + +G + + LLP
Sbjct: 460 YALENFVENLGPKVQPYLPELMECMLQLLRNPSSPRAKELAVSALGAIATAAQASLLPYF 519
Query: 974 -----RLRKQLAAGRPHTRSTVITAVK---FLISDQPHPIDPLLKSFIG---EFMESLQD 1022
LR+ L GR + I +++ L P+ PL + + + D
Sbjct: 520 PAIMEHLREFLLTGREDLQPVQIQSLETLGVLARAVGEPMRPLAEECCQLGLGLCDQVDD 579
Query: 1023 PDLNVRRATLAFF 1035
PDL RR T + F
Sbjct: 580 PDL--RRCTYSLF 590
>gi|4826730 FK506 binding protein 12-rapamycin associated protein 1
[Homo sapiens]
Length = 2549
Score = 50.1 bits (118), Expect = 1e-05
Identities = 86/388 (22%), Positives = 152/388 (39%), Gaps = 37/388 (9%)
Query: 655 HILASFLRKNQRALRLATLAALDALAQSQGLSLPPSAVQAVLAELPALVNESDMHVAQLA 714
H+L+ ++ +R L L +S+ P + + A LP + H Q A
Sbjct: 419 HVLSCVKKEKERTAAFQALGLLSVAVRSEFKVYLPRVLDIIRAALPP---KDFAHKRQKA 475
Query: 715 VDFLATVTQAQPASLVEVSGPVLSELLRLLRSPLLPAGVLAAAEGFLQALVGTRPPCVDY 774
+ ATV + L GP + + ++ L P+L G+ A L L P
Sbjct: 476 MQVDATVFTCI-SMLARAMGPGIQQDIKELLEPMLAVGLSPALTAVLYDLSRQIPQLKKD 534
Query: 775 AK--LISLLTAPVYEQAVDGGPGLHKQVFHSLARCVAALSAACPQEAASTASRLVCDARS 832
+ L+ +L+ + + + PG+ K + H LA + P+ + + L
Sbjct: 535 IQDGLLKMLSLVLMHKPLRH-PGMPKGLAHQLA---SPGLTTLPEASDVGSITLALRTLG 590
Query: 833 PHSSTGVKVLAFLSLAEVGQVAGPGHQRELKAVLLEA------LGSPSEDVRAAASYALG 886
G + F V A E K + +EA L +PS + + ++ +
Sbjct: 591 SFEFEGHSLTQF-----VRHCADHFLNSEHKEIRMEAARTCSRLLTPSIHLISGHAHVVS 645
Query: 887 RVGAGSLPDFLPFLLEQ--IEAEPRRQYLLLHSLREALGAAQPDSLKPYAEDIWALLFQR 944
+ + D L LL + +P +Y +L SL E D+ AE++ AL
Sbjct: 646 QTAVQVVADVLSKLLVVGITDPDPDIRYCVLASLDERF-----DAHLAQAENLQALFVAL 700
Query: 945 CEGAEEGTRGVVAECIGKLVLVNPSFLLPRLRKQLAAGRPHTRSTVITAVK--------F 996
+ E R + +G+L +NP+F++P LRK L + I +K
Sbjct: 701 NDQVFE-IRELAICTVGRLSSMNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSARMLGH 759
Query: 997 LISDQPHPIDPLLKSFIGEFMESLQDPD 1024
L+S+ P I P ++ + + L+DPD
Sbjct: 760 LVSNAPRLIRPYMEPILKALILKLKDPD 787
>gi|54607053 GCN1 general control of amino-acid synthesis 1-like 1
[Homo sapiens]
Length = 2671
Score = 42.0 bits (97), Expect = 0.004
Identities = 133/618 (21%), Positives = 225/618 (36%), Gaps = 76/618 (12%)
Query: 437 VVKALQRQLKDRSVRARQGCFSLLTELAGVLPGSLAEHMPVLVSGIIFSLADRSSSS-TI 495
V+ L D + RQ + + P +L E +P L ++ LA + TI
Sbjct: 1885 VLAGLYMGRSDTQLVVRQASLHVWKIVVSNTPRTLREILPTLFGLLLGFLASTCADKRTI 1944
Query: 496 RMDALAFLQGLLGTEPAEAFHPHLPILLPPVMACVADSFYKIAAEALVVLQELVRALWPL 555
L L LG + +LP ++ + + ++ Q + L +
Sbjct: 1945 AARTLGDLVRKLGEK-----------ILPEIIPILEEGLRSQKSDER---QGVCIGLSEI 1990
Query: 556 HRPRMLDPEPYVGEMSAVTLARLRATDLDQEVKERAISCMGHLVGHLGDRLGDDLEPTLL 615
+ D Y E S V AR D +EV+E A L +G + +D+ P LL
Sbjct: 1991 MKSTSRDAVLYFSE-SLVPTARKALCDPLEEVREAAAKTFEQLHSTIGHQALEDILPFLL 2049
Query: 616 LLLDRLR------NEITRLPAIKALTLVAVSPLQLDLQPILAEALHILASFLRKNQRALR 669
LD + + ++ AIK+ ++ +L P+ N R L
Sbjct: 2050 KQLDDEEVSEFALDGLKQVMAIKSRVVLPYLVPKLTTPPV--------------NTRVLA 2095
Query: 670 LATLAALDALAQSQGLSLPPSAVQAVLAELPALVNESDMHVAQLAVDFLATVTQAQPASL 729
+ A DAL + G+ LP AV L E +E + +A L+ +
Sbjct: 2096 FLSSVAGDALTRHLGVILP--AVMLALKEKLGTPDEQ-LEMANCQAVILSVEDDTGHRII 2152
Query: 730 VEVSGPVLSELLRLLRSPLLPAGVLAAAEGFLQALVGTRPPCVDYAKLISLLTAPVYEQA 789
+E +LL RSP G+ AA L DY + L + +
Sbjct: 2153 IE-------DLLEATRSP--EVGMRQAAAIILNIYCSRSK--ADYTSHLRSLVSGLIRLF 2201
Query: 790 VDGGPGLHKQVFHSLARCVAALSAACPQ---EAASTASRLVCDARSPHSSTGV-----KV 841
D P + ++ + +L L A E RL+ + G V
Sbjct: 2202 NDSSPVVLEESWDALNAITKKLDAGNQLALIEELHKEIRLIGNESKGEHVPGFCLPKKGV 2261
Query: 842 LAFLSLAEVGQVAGPGHQRELKAVLLEALGSPSEDVRAAASYALGRVGAGSLPDFLPFLL 901
+ L + G + G Q+E A +ALG +R ++ AL + L
Sbjct: 2262 TSILPVLREGVLTGSPEQKEEAA---KALGLV---IRLTSADALRPSVVSITGPLIRILG 2315
Query: 902 EQIEAEPRRQYLLLHSLREALGAAQPDSLKPYAEDIWALLFQRCEGAEEGTRGVVAECIG 961
++ + L SL L A +LKP+ + + + + G R A+ +G
Sbjct: 2316 DRFSWNVKAALLETLSL---LLAKVGIALKPFLPQLQTTFTKALQDSNRGVRLKAADALG 2372
Query: 962 KL----VLVNPSF--LLPRLRKQLAAGRPHTRSTVITAVKFLISDQPHPIDPLLKSFIGE 1015
KL + V+P F LL +R A P R T++ A++F+I +D +++ I
Sbjct: 2373 KLISIHIKVDPLFTELLNGIR---AMEDPGVRDTMLQALRFVIQGAGAKVDAVIRKNIVS 2429
Query: 1016 FMESLQDPDLNVRRATLA 1033
+ S+ D + R + A
Sbjct: 2430 LLLSMLGHDEDNTRISSA 2447
Score = 35.8 bits (81), Expect = 0.26
Identities = 37/142 (26%), Positives = 61/142 (42%), Gaps = 11/142 (7%)
Query: 30 LMSELQKDSIQLDEDSERKVVKMLLRLLEDKNGEVQNLAVKCLGPLVVKVKEYQVETIVD 89
LM L K + + + +V L+ L + +VQ CL PLV +KE I
Sbjct: 1322 LMGSLAKH-LDKSDPKVKPIVAKLIAALSTPSQQVQESVASCLPPLVPAIKEDAGGMIQR 1380
Query: 90 TLCTNMRSDKEQLRDIAGIGLKTVLSELPPAATGSGLATNVCRKITGQLTSAIAQQEDVA 149
+ + SDK R A GL ++ G G+ + +++ LT AI +++
Sbjct: 1381 LMQQLLESDKYAERKGAAYGLAGLVK-------GLGILSLKQQEMMAALTDAIQDKKNFR 1433
Query: 150 VQ---LEALDILSDMLSRLGVP 168
+ L A ++L ML +L P
Sbjct: 1434 RREGALFAFEMLCTMLGKLFEP 1455
Score = 34.3 bits (77), Expect = 0.76
Identities = 54/233 (23%), Positives = 93/233 (39%), Gaps = 33/233 (14%)
Query: 434 VPLVVKALQRQLKDRSVRARQGCFSLLTELAGVLPGSLAEHMPVLVSGIIFSLAD----- 488
V LV+ +L L++ S R + G LL +A P L+ +P +V + L D
Sbjct: 1495 VKLVLPSLLAALEEESWRTKAGSVELLGAMAYCAPKQLSSCLPNIVPKLTEVLTDSHVKV 1554
Query: 489 --------RSSSSTIRM-DALAFLQGLLG--TEPAEAFHPHLPILLPP------------ 525
R S IR + LA LL T+P+ L LL
Sbjct: 1555 QKAGQQALRQIGSVIRNPEILAIAPVLLDALTDPSRKTQKCLQTLLDTKFVHFIDAPSLA 1614
Query: 526 -VMACVADSFYKIAAEALVVLQELVRALWPLHRPRMLDPEPYVGEMSAVTLARLRATDLD 584
+M V +F + + + +++ ++ L + D PY+ ++ A L D
Sbjct: 1615 LIMPIVQRAFQDRSTDTRKMAAQIIGNMYSLTDQK--DLAPYLPSVTPGLKASL--LDPV 1670
Query: 585 QEVKERAISCMGHLVGHLGDRLGDDLEPTLLLLLDRLRNEITRLPAIKALTLV 637
EV+ + +G +V +G+ +DL P L+ L ++ + R A + L V
Sbjct: 1671 PEVRTVSAKALGAMVKGMGESCFEDLLPWLMETLTYEQSSVDRSGAAQGLAEV 1723
>gi|214010175 CLIP-associating protein 1 isoform 3 [Homo sapiens]
Length = 1471
Score = 41.6 bits (96), Expect = 0.005
Identities = 48/215 (22%), Positives = 98/215 (45%), Gaps = 21/215 (9%)
Query: 8 ISSLLEKMTSSDK--DFRFMATSDLMSELQKDSIQLDEDSERKVVKMLLRLLEDKNGEVQ 65
++ LL+++++ ++ + R A +L+ ++DS+ + E+ + ++ +LL L DK+ ++
Sbjct: 1237 VADLLKELSNHNERVEERKGALLELLKITREDSLGVWEEHFKTILLLLLETLGDKDHSIR 1296
Query: 66 NLAVKCLGPLV----VKVKEYQVETIVDTLCTNMRSDKEQLRDIAGIGLKTVLSELPPAA 121
LA++ L ++ + K Y TI+ TL + S KE +R +E +
Sbjct: 1297 ALALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVVR----------AAEEAAST 1346
Query: 122 TGSGLATNVCRKITGQLTSAIAQQEDVAVQLEALDILSDMLSRLG-VPLGAFHASLLHCL 180
S + C K+ I Q D + L A+ + + ++ R+ L ++ L
Sbjct: 1347 LASSIHPEQCIKV----LCPIIQTADYPINLAAIKMQTKVVERIAKESLLQLLVDIIPGL 1402
Query: 181 LPQLSSPRLAVRKRAVGALGHLAAACSTDLFVELA 215
L + +VRK +V L + + DL LA
Sbjct: 1403 LQGYDNTESSVRKASVFCLVAIYSVIGEDLKPHLA 1437
>gi|214010173 CLIP-associating protein 1 isoform 2 [Homo sapiens]
Length = 1479
Score = 41.6 bits (96), Expect = 0.005
Identities = 48/215 (22%), Positives = 98/215 (45%), Gaps = 21/215 (9%)
Query: 8 ISSLLEKMTSSDK--DFRFMATSDLMSELQKDSIQLDEDSERKVVKMLLRLLEDKNGEVQ 65
++ LL+++++ ++ + R A +L+ ++DS+ + E+ + ++ +LL L DK+ ++
Sbjct: 1245 VADLLKELSNHNERVEERKGALLELLKITREDSLGVWEEHFKTILLLLLETLGDKDHSIR 1304
Query: 66 NLAVKCLGPLV----VKVKEYQVETIVDTLCTNMRSDKEQLRDIAGIGLKTVLSELPPAA 121
LA++ L ++ + K Y TI+ TL + S KE +R +E +
Sbjct: 1305 ALALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVVR----------AAEEAAST 1354
Query: 122 TGSGLATNVCRKITGQLTSAIAQQEDVAVQLEALDILSDMLSRLG-VPLGAFHASLLHCL 180
S + C K+ I Q D + L A+ + + ++ R+ L ++ L
Sbjct: 1355 LASSIHPEQCIKV----LCPIIQTADYPINLAAIKMQTKVVERIAKESLLQLLVDIIPGL 1410
Query: 181 LPQLSSPRLAVRKRAVGALGHLAAACSTDLFVELA 215
L + +VRK +V L + + DL LA
Sbjct: 1411 LQGYDNTESSVRKASVFCLVAIYSVIGEDLKPHLA 1445
>gi|31563537 CLIP-associating protein 1 isoform 1 [Homo sapiens]
Length = 1538
Score = 41.6 bits (96), Expect = 0.005
Identities = 48/215 (22%), Positives = 98/215 (45%), Gaps = 21/215 (9%)
Query: 8 ISSLLEKMTSSDK--DFRFMATSDLMSELQKDSIQLDEDSERKVVKMLLRLLEDKNGEVQ 65
++ LL+++++ ++ + R A +L+ ++DS+ + E+ + ++ +LL L DK+ ++
Sbjct: 1304 VADLLKELSNHNERVEERKGALLELLKITREDSLGVWEEHFKTILLLLLETLGDKDHSIR 1363
Query: 66 NLAVKCLGPLV----VKVKEYQVETIVDTLCTNMRSDKEQLRDIAGIGLKTVLSELPPAA 121
LA++ L ++ + K Y TI+ TL + S KE +R +E +
Sbjct: 1364 ALALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVVR----------AAEEAAST 1413
Query: 122 TGSGLATNVCRKITGQLTSAIAQQEDVAVQLEALDILSDMLSRLG-VPLGAFHASLLHCL 180
S + C K+ I Q D + L A+ + + ++ R+ L ++ L
Sbjct: 1414 LASSIHPEQCIKV----LCPIIQTADYPINLAAIKMQTKVVERIAKESLLQLLVDIIPGL 1469
Query: 181 LPQLSSPRLAVRKRAVGALGHLAAACSTDLFVELA 215
L + +VRK +V L + + DL LA
Sbjct: 1470 LQGYDNTESSVRKASVFCLVAIYSVIGEDLKPHLA 1504
>gi|57863301 CLIP-associating protein 2 [Homo sapiens]
Length = 1506
Score = 40.4 bits (93), Expect = 0.011
Identities = 44/210 (20%), Positives = 94/210 (44%), Gaps = 21/210 (10%)
Query: 8 ISSLLEKMTSSDK--DFRFMATSDLMSELQKDSIQLDEDSERKVVKMLLRLLEDKNGEVQ 65
++ LL+++++ ++ + R +A +LM Q++S + ++ + ++ +LL L DK ++
Sbjct: 1272 VAELLKELSNHNERVEERKIALYELMKLTQEESFSVWDEHFKTILLLLLETLGDKEPTIR 1331
Query: 66 NLAVKCLGPLV----VKVKEYQVETIVDTLCTNMRSDKEQLRDIAGIGLKTVLSELPPAA 121
LA+K L ++ + K Y T++ TL + KE +R
Sbjct: 1332 ALALKVLREILRHQPARFKNYAELTVMKTLEAHKDPHKEVVRS--------------AEE 1377
Query: 122 TGSGLATNVCRKITGQLTSAIAQQEDVAVQLEALDILSDMLSRLG-VPLGAFHASLLHCL 180
S LAT++ + ++ I Q D + L A+ + + ++ R+ L ++ L
Sbjct: 1378 AASVLATSISPEQCIKVLCPIIQTADYPINLAAIKMQTKVIERVSKETLNLLLPEIMPGL 1437
Query: 181 LPQLSSPRLAVRKRAVGALGHLAAACSTDL 210
+ + +VRK V L + A +L
Sbjct: 1438 IQGYDNSESSVRKACVFCLVAVHAVIGDEL 1467
>gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding
protein homolog 1 [Homo sapiens]
Length = 557
Score = 39.7 bits (91), Expect = 0.018
Identities = 20/36 (55%), Positives = 23/36 (63%), Gaps = 1/36 (2%)
Query: 311 DPNYNYDSDEDEEQMETEDSEFSEQESEDEYSDDDD 346
D YNY+ DEDEE E EDS E+E ED+ DDD
Sbjct: 4 DEGYNYEFDEDEECSE-EDSGAEEEEDEDDDEPDDD 38
>gi|32455246 beta isoform of regulatory subunit A, protein phosphatase
2 isoform a [Homo sapiens]
Length = 601
Score = 38.5 bits (88), Expect = 0.040
Identities = 100/458 (21%), Positives = 172/458 (37%), Gaps = 67/458 (14%)
Query: 607 GDDLEPTLLLLLDRLRNEIT--RLPAIKALTLVAVSPLQLDLQPILAEALHILASFLRKN 664
GDD + +L+D LRNE RL +IK L+ +A L L ++ +E L L +
Sbjct: 18 GDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIA---LALGVERTRSELLPFLTDTIYDE 74
Query: 665 QRALRLATLAALDALAQSQGLSLPPSAVQAVLAELPALVNESDMHVAQLAVDFLATVTQA 724
L LA + L GL P +L L L + V AV+ L ++Q
Sbjct: 75 DEVL----LALAEQLGNFTGLVGGPDFAHCLLPPLENLATVEETVVRDKAVESLRQISQE 130
Query: 725 Q-PASLVEVSGPVLSELLRLLRSPLLPAGVLAAAEGFLQALVGTRPPCVDYAKLISLLTA 783
P +L P++ LA+ + F V Y + + + A
Sbjct: 131 HTPVALEAYFVPLVKR--------------LASGDWFTSRTSACGLFSVCYPRASNAVKA 176
Query: 784 PVYEQ----AVDGGPGLHKQVFHSLARCVAALSAACPQEAASTASRLV--CDARSPHSST 837
+ +Q D P + + L L E S S +V + +
Sbjct: 177 EIRQQFRSLCSDDTPMVRRAAASKLGEFAKVL------ELDSVKSEIVPLFTSLASDEQD 230
Query: 838 GVKVLAFLSLAEVGQVAGPGHQRELKAVLLEALGSPSEDVRAAASYALG------RVGAG 891
V++LA + + Q+ Q +L+ +++ L +ED Y + + G
Sbjct: 231 SVRLLAVEACVSIAQLLS---QDDLETLVMPTLRQAAEDKSWRVRYMVADRFSELQKAMG 287
Query: 892 ---SLPDFLPF---LLEQIEAEPRRQYLLLHSLREALGAAQP---------DSLKPYAED 936
+L D +P LL+ EAE R H ++E LG P + + PY ++
Sbjct: 288 PKITLNDLIPAFQNLLKDCEAEVRA--AAAHKVKE-LGENLPIEDRETIIMNQILPYIKE 344
Query: 937 IWALLFQRCEGAEEGTRGVVAECIGKLVLVNPSFLLPRLRKQLAAGRPHTRSTVITAVKF 996
+ + Q + A ++ +GK + LLP QL P R +I+ +
Sbjct: 345 LVSDTNQHVKSALASVIMGLSTILGKENTI--EHLLPLFLAQLKDECPDVRLNIISNLDC 402
Query: 997 LISDQPHPIDPLLKSFIGEFMESLQDPDLNVRRATLAF 1034
+ ++ I L +S + +E +D VR A + +
Sbjct: 403 V--NEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEY 438
>gi|32455244 beta isoform of regulatory subunit A, protein phosphatase
2 isoform b [Homo sapiens]
Length = 667
Score = 38.5 bits (88), Expect = 0.040
Identities = 100/458 (21%), Positives = 172/458 (37%), Gaps = 67/458 (14%)
Query: 607 GDDLEPTLLLLLDRLRNEIT--RLPAIKALTLVAVSPLQLDLQPILAEALHILASFLRKN 664
GDD + +L+D LRNE RL +IK L+ +A L L ++ +E L L +
Sbjct: 18 GDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIA---LALGVERTRSELLPFLTDTIYDE 74
Query: 665 QRALRLATLAALDALAQSQGLSLPPSAVQAVLAELPALVNESDMHVAQLAVDFLATVTQA 724
L LA + L GL P +L L L + V AV+ L ++Q
Sbjct: 75 DEVL----LALAEQLGNFTGLVGGPDFAHCLLPPLENLATVEETVVRDKAVESLRQISQE 130
Query: 725 Q-PASLVEVSGPVLSELLRLLRSPLLPAGVLAAAEGFLQALVGTRPPCVDYAKLISLLTA 783
P +L P++ LA+ + F V Y + + + A
Sbjct: 131 HTPVALEAYFVPLVKR--------------LASGDWFTSRTSACGLFSVCYPRASNAVKA 176
Query: 784 PVYEQ----AVDGGPGLHKQVFHSLARCVAALSAACPQEAASTASRLV--CDARSPHSST 837
+ +Q D P + + L L E S S +V + +
Sbjct: 177 EIRQQFRSLCSDDTPMVRRAAASKLGEFAKVL------ELDSVKSEIVPLFTSLASDEQD 230
Query: 838 GVKVLAFLSLAEVGQVAGPGHQRELKAVLLEALGSPSEDVRAAASYALG------RVGAG 891
V++LA + + Q+ Q +L+ +++ L +ED Y + + G
Sbjct: 231 SVRLLAVEACVSIAQLLS---QDDLETLVMPTLRQAAEDKSWRVRYMVADRFSELQKAMG 287
Query: 892 ---SLPDFLPF---LLEQIEAEPRRQYLLLHSLREALGAAQP---------DSLKPYAED 936
+L D +P LL+ EAE R H ++E LG P + + PY ++
Sbjct: 288 PKITLNDLIPAFQNLLKDCEAEVRA--AAAHKVKE-LGENLPIEDRETIIMNQILPYIKE 344
Query: 937 IWALLFQRCEGAEEGTRGVVAECIGKLVLVNPSFLLPRLRKQLAAGRPHTRSTVITAVKF 996
+ + Q + A ++ +GK + LLP QL P R +I+ +
Sbjct: 345 LVSDTNQHVKSALASVIMGLSTILGKENTI--EHLLPLFLAQLKDECPDVRLNIISNLDC 402
Query: 997 LISDQPHPIDPLLKSFIGEFMESLQDPDLNVRRATLAF 1034
+ ++ I L +S + +E +D VR A + +
Sbjct: 403 V--NEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEY 438
>gi|21361399 alpha isoform of regulatory subunit A, protein
phosphatase 2 [Homo sapiens]
Length = 589
Score = 37.4 bits (85), Expect = 0.089
Identities = 93/471 (19%), Positives = 170/471 (36%), Gaps = 84/471 (17%)
Query: 607 GDDLEPTLLLLLDRLRNEIT--RLPAIKALTLVAVSPLQLDLQPILAEALHILASFLRKN 664
GDD + +L+D LRNE RL +IK L+ +A L L ++ +E L L +
Sbjct: 6 GDDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIA---LALGVERTRSELLPFLTDTIYDE 62
Query: 665 QRALRLATLAALDALAQSQGLSLPPSAVQAVLAELPALVNESDMHVAQLAVDFLATVTQA 724
L LA + L L P V +L L +L + V AV+ L ++
Sbjct: 63 DEVL----LALAEQLGTFTTLVGGPEYVHCLLPPLESLATVEETVVRDKAVESLRAISHE 118
Query: 725 QPASLVEVSGPVLSELLRLLRSPLLPAGVLAAAEGFLQALVGTRPPCVDYAKLISLLTAP 784
S +E + + L++ LA + F V Y ++ S + A
Sbjct: 119 HSPSDLE------AHFVPLVKR-------LAGGDWFTSRTSACGLFSVCYPRVSSAVKAE 165
Query: 785 VYEQ----AVDGGPGLHKQVFHSLARCVAALSA-ACPQEAASTASRLVCDARSPHSSTGV 839
+ + D P + + L L E S L D + V
Sbjct: 166 LRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQD-----SV 220
Query: 840 KVLAFLSLAEVGQVAGPGHQRELKAVLLEALGSPSEDVRAAASYALGRVGAGSLPDFLPF 899
++LA + + Q+ Q +L+A+++ L +ED
Sbjct: 221 RLLAVEACVNIAQLL---PQEDLEALVMPTLRQAAED----------------------- 254
Query: 900 LLEQIEAEPRRQYLLLHSLREALGAAQPDSLKPYAEDIWALLFQRCEG---------AEE 950
R +Y++ E A P+ K + L + CE +E
Sbjct: 255 ------KSWRVRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKE 308
Query: 951 GTRGVVAECIGKLVLVNPSFLLPRLRKQLAAGRPHTRSTVITAVKFL--ISDQPHPIDPL 1008
+ A+C +++ S +LP +++ ++ H +S + + + L I + + I+ L
Sbjct: 309 FCENLSADCRENVIM---SQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHL 365
Query: 1009 LKSFIGEFMESLQDPDLNVRRATLAFFNSAVHNKPSLVRDLLDDILPLLYQ 1059
L F+ + + + LN+ N N+ +R L +LP + +
Sbjct: 366 LPLFLAQLKDECPEVRLNI------ISNLDCVNEVIGIRQLSQSLLPAIVE 410
>gi|150456415 HEAT repeat containing 5A [Homo sapiens]
Length = 1753
Score = 37.4 bits (85), Expect = 0.089
Identities = 54/299 (18%), Positives = 109/299 (36%), Gaps = 24/299 (8%)
Query: 66 NLAVKCLGPLVVKVKEYQVETIVDTLCTNMRSDKEQLRDIAGIGLKTVLSELPPAATGSG 125
+L + GPL E + I+ L N+ ++ G L +++ L P G+
Sbjct: 671 SLIIDSAGPLYYVHVEPTLSLII-MLLLNVPPTHAEVHQSLGRCLNALITTLGPELQGNS 729
Query: 126 LATNVCRKITGQLTSAIAQQEDVAVQLEALDILSDMLSRLGVPLGAFHASLLHCLLPQLS 185
+ + R + + D VQ +A+ L + + P +SL+ CL L
Sbjct: 730 TSISTLRTSCLLGCAVMQDNPDCLVQAQAISCLQQL--HMFAPRHVNLSSLVSCLCVNLC 787
Query: 186 SPRLAVRKRAVGALGHLAAACSTDLFVELADHLLDRLPGPRVPTSPTAIRTLIQCLGSVG 245
SP L +R+ + L L + E+++H + R +P A + VG
Sbjct: 788 SPYLLLRRAVLACLRQLVQREAA----EVSEHAVMLAKDSREELTPDAN------IREVG 837
Query: 246 RQAGHRLGAHLDRLVPLVEDFCNLDDDELRESCLQAFEAFLRKCPKEMGPHVPNVTSLCL 305
+ + + L D + L ++ +L+ C + C+
Sbjct: 838 LEGALLILLDKETDERLCHDIKETLNYMLTSMAVEKLSLWLKLCKDVLAASADFTAVTCV 897
Query: 306 QYIKHDPNYNYDSDEDEEQMETEDSEFSEQESEDEYSDDDDMSWKVRRAAAKCIAALIS 364
D+ ++EE + +D+ +++ + W R AA+C+ +I+
Sbjct: 898 -----------DTMQEEEGDKGDDASVLTTRRDEKSHPFTNPRWATRVFAAECVCRIIN 945
>gi|120431745 huntingtin-associated protein 1 isoform 4 [Homo
sapiens]
Length = 594
Score = 37.0 bits (84), Expect = 0.12
Identities = 26/89 (29%), Positives = 40/89 (44%), Gaps = 8/89 (8%)
Query: 307 YIKHDPNYNYD-----SDEDEEQMETEDSEFSEQESEDEYSDDDDMSWKVRRAAAKCIAA 361
Y++H N + SD DEE ED E E+E E E +++ + + + A C A
Sbjct: 241 YLRHQVNLRDELLQLYSDSDEED---EDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAP 297
Query: 362 LISSRPDLLPDFHCTLAPVLIRRFKEREE 390
+ S+ LL HC L + + EE
Sbjct: 298 KLISQEALLHQHHCPQLEALQEKLRLLEE 326
>gi|120431743 huntingtin-associated protein 1 isoform 3 [Homo
sapiens]
Length = 602
Score = 37.0 bits (84), Expect = 0.12
Identities = 26/89 (29%), Positives = 40/89 (44%), Gaps = 8/89 (8%)
Query: 307 YIKHDPNYNYD-----SDEDEEQMETEDSEFSEQESEDEYSDDDDMSWKVRRAAAKCIAA 361
Y++H N + SD DEE ED E E+E E E +++ + + + A C A
Sbjct: 249 YLRHQVNLRDELLQLYSDSDEED---EDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAP 305
Query: 362 LISSRPDLLPDFHCTLAPVLIRRFKEREE 390
+ S+ LL HC L + + EE
Sbjct: 306 KLISQEALLHQHHCPQLEALQEKLRLLEE 334
>gi|120431738 huntingtin-associated protein 1 isoform 2 [Homo
sapiens]
Length = 619
Score = 37.0 bits (84), Expect = 0.12
Identities = 26/89 (29%), Positives = 40/89 (44%), Gaps = 8/89 (8%)
Query: 307 YIKHDPNYNYD-----SDEDEEQMETEDSEFSEQESEDEYSDDDDMSWKVRRAAAKCIAA 361
Y++H N + SD DEE ED E E+E E E +++ + + + A C A
Sbjct: 241 YLRHQVNLRDELLQLYSDSDEED---EDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAP 297
Query: 362 LISSRPDLLPDFHCTLAPVLIRRFKEREE 390
+ S+ LL HC L + + EE
Sbjct: 298 KLISQEALLHQHHCPQLEALQEKLRLLEE 326
>gi|109134349 coatomer protein complex, subunit gamma 2 [Homo
sapiens]
Length = 871
Score = 35.8 bits (81), Expect = 0.26
Identities = 61/259 (23%), Positives = 107/259 (41%), Gaps = 38/259 (14%)
Query: 650 LAEALHILASFLRKNQRALRLATLAALDALAQSQGLSLPPSAVQAVLAELPALVNESDMH 709
LA A+ +L F + ALR A + L+ +A PSAV A +L L+ +S+
Sbjct: 285 LAPAVSVLQLFCSSPKPALRYAAVRTLNKVAMKH-----PSAVTACNLDLENLITDSNRS 339
Query: 710 VAQLAV-DFLATVTQAQPASLVEVSGPVLSELLRLLRSPLLPAGVLAAAEGFLQALVGTR 768
+A LA+ L T +++ L++ +SE+ + ++ A + AL
Sbjct: 340 IATLAITTLLKTGSESSVDRLMKQISSFVSEISDEFKVVVVQA---------ISAL---- 386
Query: 769 PPCVDYAKLISLLTAPVYEQAVDGGPGLHKQVFHSLARCVAALSAACPQEAASTASRLVC 828
C Y + S++ + D G +K+ ++ C+ ++ P+ + + L C
Sbjct: 387 --CQKYPRKHSVMMTFLSNMLRDDGGFEYKR---AIVDCIISIVEENPESKEAGLAHL-C 440
Query: 829 D--ARSPHSSTGVKVLAFLSLAEVGQVAGPGHQRELKAV--LLEALGSPSEDVRAAASYA 884
+ H+ K+L L GP K + + + +E VRAAA A
Sbjct: 441 EFIEDCEHTVLATKILHLLG------KEGPRTPVPSKYIRFIFNRVVLENEAVRAAAVSA 494
Query: 885 LGRVGAGS---LPDFLPFL 900
L + GA + LP L L
Sbjct: 495 LAKFGAQNESLLPSILVLL 513
>gi|23510381 transportin 1 isoform 2 [Homo sapiens]
Length = 890
Score = 35.4 bits (80), Expect = 0.34
Identities = 66/278 (23%), Positives = 105/278 (37%), Gaps = 59/278 (21%)
Query: 129 NVCRKITGQLTSAIAQQEDVAVQLEALDILSDMLSR-LGVPLGAFHASLLHCLLPQLSSP 187
N C G L ED A E LD SD+L R L + + F H SSP
Sbjct: 143 NTCEGAFGALQKIC---EDSA---EILD--SDVLDRPLNIMIPKFLQFFKH------SSP 188
Query: 188 RLAVRKRAVGALGHLAAACSTDLFVELADHLLDRLPGPRVPTSPTAIRTLIQCLGSVGRQ 247
+ +R AV + + + L + + D ++ L P + + + L +
Sbjct: 189 K--IRSHAVACVNQFIISRTQALMLHI-DSFIENLFALAGDEEPEVRKNVCRALVML--- 242
Query: 248 AGHRLGAHLDRLVP----LVEDFCNLDDDELRESCLQAFEAFLRK-----CPKEMGPHVP 298
L +DRL+P +VE D+ L+A E +L C + H+P
Sbjct: 243 ----LEVRMDRLLPHMHNIVEYMLQRTQDQDENVALEACEFWLTLAEQPICKDVLVRHLP 298
Query: 299 NVTSLCLQYIKHDPN----YNYDSDEDEE-------------------QMETEDSEFSEQ 335
+ + + +K+ D +EDE Q ED E
Sbjct: 299 KLIPVLVNGMKYSDIDIILLKGDVEEDETIPDSEQDIRPRFHRSRTVAQQHDEDGIEEED 358
Query: 336 ESEDEYSDDDDMS-WKVRRAAAKCIAALIS-SRPDLLP 371
+ +DE DDD +S W +R+ +A + L + R +LLP
Sbjct: 359 DDDDEIDDDDTISDWNLRKCSAAALDVLANVYRDELLP 396
Score = 32.0 bits (71), Expect = 3.7
Identities = 42/166 (25%), Positives = 70/166 (42%), Gaps = 26/166 (15%)
Query: 460 LTELAGVLPGSLAEHMPVLVSGIIFS---LADRSSSSTIRMDALAFLQGLLGTEPAEAFH 516
L LA V L H+ L+ ++F + S + A +QG++
Sbjct: 383 LDVLANVYRDELLPHILPLLKELLFHHEWVVKESGILVLGAIAEGCMQGMI--------- 433
Query: 517 PHLPILLPPVMACVADSFYKIAAEALVVLQELVR-ALWPLHRPRMLDPEPYVGEMSAVTL 575
P+LP L+P ++ C++D K A + L R A W + +P P+ Y+ + L
Sbjct: 434 PYLPELIPHLIQCLSD---KKALVRSITCWTLSRYAHWVVSQP----PDTYLKPLMTELL 486
Query: 576 ARLRATDLDQEVKERAISCMGHLVGHLGDRLGDDLEPTLLLLLDRL 621
R+ D ++ V+E A S L + +L P L +LD L
Sbjct: 487 KRI--LDSNKRVQEAACSAF----ATLEEEACTELVPYLAYILDTL 526
>gi|133925811 transportin 1 isoform 1 [Homo sapiens]
Length = 898
Score = 35.4 bits (80), Expect = 0.34
Identities = 66/278 (23%), Positives = 105/278 (37%), Gaps = 59/278 (21%)
Query: 129 NVCRKITGQLTSAIAQQEDVAVQLEALDILSDMLSR-LGVPLGAFHASLLHCLLPQLSSP 187
N C G L ED A E LD SD+L R L + + F H SSP
Sbjct: 151 NTCEGAFGALQKIC---EDSA---EILD--SDVLDRPLNIMIPKFLQFFKH------SSP 196
Query: 188 RLAVRKRAVGALGHLAAACSTDLFVELADHLLDRLPGPRVPTSPTAIRTLIQCLGSVGRQ 247
+ +R AV + + + L + + D ++ L P + + + L +
Sbjct: 197 K--IRSHAVACVNQFIISRTQALMLHI-DSFIENLFALAGDEEPEVRKNVCRALVML--- 250
Query: 248 AGHRLGAHLDRLVP----LVEDFCNLDDDELRESCLQAFEAFLRK-----CPKEMGPHVP 298
L +DRL+P +VE D+ L+A E +L C + H+P
Sbjct: 251 ----LEVRMDRLLPHMHNIVEYMLQRTQDQDENVALEACEFWLTLAEQPICKDVLVRHLP 306
Query: 299 NVTSLCLQYIKHDPN----YNYDSDEDEE-------------------QMETEDSEFSEQ 335
+ + + +K+ D +EDE Q ED E
Sbjct: 307 KLIPVLVNGMKYSDIDIILLKGDVEEDETIPDSEQDIRPRFHRSRTVAQQHDEDGIEEED 366
Query: 336 ESEDEYSDDDDMS-WKVRRAAAKCIAALIS-SRPDLLP 371
+ +DE DDD +S W +R+ +A + L + R +LLP
Sbjct: 367 DDDDEIDDDDTISDWNLRKCSAAALDVLANVYRDELLP 404
Score = 32.0 bits (71), Expect = 3.7
Identities = 42/166 (25%), Positives = 70/166 (42%), Gaps = 26/166 (15%)
Query: 460 LTELAGVLPGSLAEHMPVLVSGIIFS---LADRSSSSTIRMDALAFLQGLLGTEPAEAFH 516
L LA V L H+ L+ ++F + S + A +QG++
Sbjct: 391 LDVLANVYRDELLPHILPLLKELLFHHEWVVKESGILVLGAIAEGCMQGMI--------- 441
Query: 517 PHLPILLPPVMACVADSFYKIAAEALVVLQELVR-ALWPLHRPRMLDPEPYVGEMSAVTL 575
P+LP L+P ++ C++D K A + L R A W + +P P+ Y+ + L
Sbjct: 442 PYLPELIPHLIQCLSD---KKALVRSITCWTLSRYAHWVVSQP----PDTYLKPLMTELL 494
Query: 576 ARLRATDLDQEVKERAISCMGHLVGHLGDRLGDDLEPTLLLLLDRL 621
R+ D ++ V+E A S L + +L P L +LD L
Sbjct: 495 KRI--LDSNKRVQEAACSAF----ATLEEEACTELVPYLAYILDTL 534
>gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens]
Length = 619
Score = 35.4 bits (80), Expect = 0.34
Identities = 15/49 (30%), Positives = 29/49 (59%), Gaps = 2/49 (4%)
Query: 300 VTSLCLQYIKH--DPNYNYDSDEDEEQMETEDSEFSEQESEDEYSDDDD 346
+ ++CL+ ++ D D ++D++ + +D E E+E E+E DDDD
Sbjct: 119 IVNVCLEIMEPGGDGGEEDDKEDDDDDEDDDDEEDEEEEEEEEEDDDDD 167
Score = 33.1 bits (74), Expect = 1.7
Identities = 13/32 (40%), Positives = 20/32 (62%)
Query: 317 DSDEDEEQMETEDSEFSEQESEDEYSDDDDMS 348
D D+DE+ + ED E E+E ED+ D +D +
Sbjct: 141 DDDDDEDDDDEEDEEEEEEEEEDDDDDTEDFA 172
>gi|94421471 ring finger protein 17 [Homo sapiens]
Length = 1623
Score = 35.4 bits (80), Expect = 0.34
Identities = 30/128 (23%), Positives = 63/128 (49%), Gaps = 9/128 (7%)
Query: 23 RFMATSDLMSELQKDSIQLDEDSERKVVKMLLRL-----LEDKNGEVQNLAVKCLGPLVV 77
+++ T +L++ L++ I E+S+ + VK + ++DKN + ++ + +V
Sbjct: 934 QWLLTENLLNSLEEKMIAAYENSKWEPVKWENDMHCAVKIQDKNQWRRGQIIRMVTDTLV 993
Query: 78 KVKEYQV--ETIVDTLCTNMRSDKEQLRDIAGIGLKTVLSELPPAATGSGLATNVCRKIT 135
+V Y V E +V+ C +R +E L+ + + L+ L ++ PA C ++
Sbjct: 994 EVLLYDVGVELVVNVDC--LRKLEENLKTMGRLSLECSLVDIRPAGGSDKWTATACDCLS 1051
Query: 136 GQLTSAIA 143
LT A+A
Sbjct: 1052 LYLTGAVA 1059
>gi|158631177 homeodomain leucine zipper protein [Homo sapiens]
Length = 550
Score = 35.4 bits (80), Expect = 0.34
Identities = 13/31 (41%), Positives = 22/31 (70%)
Query: 317 DSDEDEEQMETEDSEFSEQESEDEYSDDDDM 347
+ +E+EE++ +D E E+E ED+ DDDD+
Sbjct: 516 EEEEEEEELPEDDEEEEEEEEEDDDDDDDDV 546
Score = 33.5 bits (75), Expect = 1.3
Identities = 15/28 (53%), Positives = 19/28 (67%)
Query: 319 DEDEEQMETEDSEFSEQESEDEYSDDDD 346
DE+EE+ E E E E+E E+E DDDD
Sbjct: 514 DEEEEEEEEELPEDDEEEEEEEEEDDDD 541
Score = 33.1 bits (74), Expect = 1.7
Identities = 13/30 (43%), Positives = 20/30 (66%)
Query: 317 DSDEDEEQMETEDSEFSEQESEDEYSDDDD 346
D +E+EE+ E + + E+E E+E DDDD
Sbjct: 514 DEEEEEEEEELPEDDEEEEEEEEEDDDDDD 543
Score = 32.3 bits (72), Expect = 2.9
Identities = 13/30 (43%), Positives = 20/30 (66%)
Query: 317 DSDEDEEQMETEDSEFSEQESEDEYSDDDD 346
+ +E+EE+ ED E E+E E++ DDDD
Sbjct: 515 EEEEEEEEELPEDDEEEEEEEEEDDDDDDD 544
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 35.0 bits (79), Expect = 0.44
Identities = 16/42 (38%), Positives = 26/42 (61%)
Query: 320 EDEEQMETEDSEFSEQESEDEYSDDDDMSWKVRRAAAKCIAA 361
ED ++ E +DSE E++ EDE D+D++ +AAA A+
Sbjct: 143 EDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPAS 184
Score = 32.7 bits (73), Expect = 2.2
Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 1/77 (1%)
Query: 264 EDFCNLDDDELRESCLQAFEAFLRKCPKEMGPHVPNVTSLCLQYIKHDPNYNYDSDEDEE 323
ED + ++D+ E ++ A +K K + NV + D + + D DED+E
Sbjct: 196 EDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAE-DEDEEEDDEDEDDDDDEDDE 254
Query: 324 QMETEDSEFSEQESEDE 340
+ ED E E+E E+E
Sbjct: 255 DDDDEDDEEEEEEEEEE 271
>gi|239749996 PREDICTED: similar to hCG1991922 [Homo sapiens]
Length = 487
Score = 35.0 bits (79), Expect = 0.44
Identities = 13/43 (30%), Positives = 25/43 (58%)
Query: 309 KHDPNYNYDSDEDEEQMETEDSEFSEQESEDEYSDDDDMSWKV 351
K + N + +EDEE+ + E+ E E + ++E DD+ W++
Sbjct: 320 KKEEEENEEDEEDEEEEKDEEDEDEEDDEDEEDGDDEQSHWQL 362
>gi|216548152 RNA pseudouridylate synthase domain containing 3
isoform 2 [Homo sapiens]
Length = 336
Score = 35.0 bits (79), Expect = 0.44
Identities = 45/146 (30%), Positives = 62/146 (42%), Gaps = 25/146 (17%)
Query: 109 GLKTVLSELPPAATGSGLATNVCRKITGQLTSAIAQQEDVAVQLEALDILSDML--SRLG 166
G+K LS ATGSG C + Q + + Q V + L+ +L D + +R+G
Sbjct: 200 GVKKTLSHFRVVATGSG-----CALVQLQPLTVFSSQLQVHMVLQLCPVLGDHMYSARVG 254
Query: 167 VPLGAFHASLLHCLLP-QLSSPRLAVRKRAVGALGHLAAACSTDLFVELADHLLDRLPGP 225
LG LLP + + P+ V A+ HL + + L + L H L LPG
Sbjct: 255 TVLGQ------RFLLPAENNKPQRQVLDEALLRRLHLTPSQAAQLPLHLHLHRL-LLPGT 307
Query: 226 R---------VPTSPTAIRTLIQCLG 242
R P P RTL QCLG
Sbjct: 308 RARDTPVELLAPLPPYFSRTL-QCLG 332
>gi|216548145 RNA pseudouridylate synthase domain containing 3
isoform 1 [Homo sapiens]
Length = 351
Score = 35.0 bits (79), Expect = 0.44
Identities = 45/146 (30%), Positives = 62/146 (42%), Gaps = 25/146 (17%)
Query: 109 GLKTVLSELPPAATGSGLATNVCRKITGQLTSAIAQQEDVAVQLEALDILSDML--SRLG 166
G+K LS ATGSG C + Q + + Q V + L+ +L D + +R+G
Sbjct: 215 GVKKTLSHFRVVATGSG-----CALVQLQPLTVFSSQLQVHMVLQLCPVLGDHMYSARVG 269
Query: 167 VPLGAFHASLLHCLLP-QLSSPRLAVRKRAVGALGHLAAACSTDLFVELADHLLDRLPGP 225
LG LLP + + P+ V A+ HL + + L + L H L LPG
Sbjct: 270 TVLGQ------RFLLPAENNKPQRQVLDEALLRRLHLTPSQAAQLPLHLHLHRL-LLPGT 322
Query: 226 R---------VPTSPTAIRTLIQCLG 242
R P P RTL QCLG
Sbjct: 323 RARDTPVELLAPLPPYFSRTL-QCLG 347
>gi|11559929 coatomer protein complex, subunit gamma 1 [Homo
sapiens]
Length = 874
Score = 35.0 bits (79), Expect = 0.44
Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 6/92 (6%)
Query: 650 LAEALHILASFLRKNQRALRLATLAALDALAQSQGLSLPPSAVQAVLAELPALVNESDMH 709
LA A+ +L F + ALR A + L+ +A PSAV A +L LV +S+
Sbjct: 285 LAPAVSVLQLFCSSPKAALRYAAVRTLNKVAMKH-----PSAVTACNLDLENLVTDSNRS 339
Query: 710 VAQLAV-DFLATVTQAQPASLVEVSGPVLSEL 740
+A LA+ L T +++ L++ +SE+
Sbjct: 340 IATLAITTLLKTGSESSIDRLMKQISSFMSEI 371
>gi|239751555 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 34.7 bits (78), Expect = 0.58
Identities = 20/61 (32%), Positives = 31/61 (50%), Gaps = 2/61 (3%)
Query: 286 LRKCPKEMGPHVPNVTSLCLQYIKHDPNYNYDSDEDEEQMETEDSEFSEQESEDEYSDDD 345
L + P G P TS C Y D + + D +E+E++++ E + E E E+E D D
Sbjct: 707 LAQHPHHRGLLSPGGTSCC--YPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPD 764
Query: 346 D 346
D
Sbjct: 765 D 765
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,400,202
Number of Sequences: 37866
Number of extensions: 2036552
Number of successful extensions: 11180
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 55
Number of HSP's successfully gapped in prelim test: 50
Number of HSP's that attempted gapping in prelim test: 9894
Number of HSP's gapped (non-prelim): 945
length of query: 1236
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1122
effective length of database: 13,930,794
effective search space: 15630350868
effective search space used: 15630350868
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.