Guide to the Human Genome
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Search of human proteins with 239758092

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239758092 PREDICTED: similar to HLA class II
histocompatibility antigen, DRB1-7 beta chain [Homo sapiens]
         (253 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239758092 PREDICTED: similar to HLA class II histocompatibili...   522   e-148
gi|239740745 PREDICTED: similar to HLA class II histocompatibili...   466   e-132
gi|239740695 PREDICTED: similar to HLA class II histocompatibili...   466   e-132
gi|239748785 PREDICTED: similar to HLA class II histocompatibili...   441   e-124
gi|155030211 major histocompatibility complex, class II, DR beta...   431   e-121
gi|17986005 major histocompatibility complex, class II, DR beta ...   424   e-119
gi|239748820 PREDICTED: hypothetical protein XP_002346811 [Homo ...   423   e-119
gi|239740857 PREDICTED: similar to major histocompatibility comp...   420   e-118
gi|239740853 PREDICTED: similar to major histocompatibility comp...   418   e-117
gi|239740859 PREDICTED: similar to major histocompatibility comp...   412   e-115
gi|239740855 PREDICTED: similar to major histocompatibility comp...   411   e-115
gi|52630344 major histocompatibility complex, class II, DR beta ...   410   e-115
gi|18641375 major histocompatibility complex, class II, DR beta ...   409   e-114
gi|239740743 PREDICTED: similar to HLA class II histocompatibili...   400   e-112
gi|239740693 PREDICTED: similar to HLA class II histocompatibili...   400   e-112
gi|239758090 PREDICTED: major histocompatibility complex, class ...   347   7e-96
gi|239758095 PREDICTED: similar to major histocompatibility comp...   286   9e-78
gi|239740749 PREDICTED: similar to major histocompatibility comp...   286   9e-78
gi|239748788 PREDICTED: similar to major histocompatibility comp...   285   3e-77
gi|239740863 PREDICTED: similar to major histocompatibility comp...   284   6e-77
gi|239513955 PREDICTED: similar to major histocompatibility comp...   284   6e-77
gi|169168591 PREDICTED: similar to major histocompatibility comp...   281   5e-76
gi|150418002 major histocompatibility complex, class II, DQ beta...   277   7e-75
gi|239740920 PREDICTED: similar to major histocompatibility comp...   275   2e-74
gi|239740918 PREDICTED: similar to major histocompatibility comp...   275   2e-74
gi|24797076 major histocompatibility complex, class II, DP beta ...   275   3e-74
gi|169217452 PREDICTED: similar to HLA class II histocompatibili...   260   7e-70
gi|169168671 PREDICTED: similar to MHC class II antigen [Homo sa...   258   3e-69
gi|4504403 major histocompatibility complex, class II, DO beta p...   246   1e-65
gi|169168589 PREDICTED: similar to MHC class II antigen [Homo sa...   146   1e-35

>gi|239758092 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain [Homo sapiens]
          Length = 253

 Score =  522 bits (1344), Expect = e-148
 Identities = 253/253 (100%), Positives = 253/253 (100%)

Query: 1   MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60
           MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF
Sbjct: 1   MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60

Query: 61  YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLLCLPDSFPLPCFLLVHPEVTVYPA 120
           YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLLCLPDSFPLPCFLLVHPEVTVYPA
Sbjct: 61  YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLLCLPDSFPLPCFLLVHPEVTVYPA 120

Query: 121 KTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETV 180
           KTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETV
Sbjct: 121 KTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETV 180

Query: 181 PRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQ 240
           PRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQ
Sbjct: 181 PRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQ 240

Query: 241 KGHSGLQPTGFLS 253
           KGHSGLQPTGFLS
Sbjct: 241 KGHSGLQPTGFLS 253


>gi|239740745 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain isoform 1 [Homo sapiens]
          Length = 266

 Score =  466 bits (1199), Expect = e-132
 Identities = 237/268 (88%), Positives = 241/268 (89%), Gaps = 17/268 (6%)

Query: 1   MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60
           MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF
Sbjct: 1   MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60

Query: 61  YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------C-----LPDSFPL 105
           YNQEEFVRFDSDVGEYRAVTELGRPVAE    Q D+L          C     + +SF +
Sbjct: 61  YNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQKDILEDRRGQVDTVCRHNYGVGESFTV 120

Query: 106 PCFLLVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ 165
                VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ
Sbjct: 121 Q--RRVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ 178

Query: 166 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLG 225
           NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLG
Sbjct: 179 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLG 238

Query: 226 LLFLGAGLFIYFRNQKGHSGLQPTGFLS 253
           LLFLGAGLFIYFRNQKGHSGLQPTGFLS
Sbjct: 239 LLFLGAGLFIYFRNQKGHSGLQPTGFLS 266


>gi|239740695 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain isoform 1 [Homo sapiens]
          Length = 266

 Score =  466 bits (1199), Expect = e-132
 Identities = 237/268 (88%), Positives = 241/268 (89%), Gaps = 17/268 (6%)

Query: 1   MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60
           MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF
Sbjct: 1   MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60

Query: 61  YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------C-----LPDSFPL 105
           YNQEEFVRFDSDVGEYRAVTELGRPVAE    Q D+L          C     + +SF +
Sbjct: 61  YNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQKDILEDRRGQVDTVCRHNYGVGESFTV 120

Query: 106 PCFLLVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ 165
                VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ
Sbjct: 121 Q--RRVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ 178

Query: 166 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLG 225
           NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLG
Sbjct: 179 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLG 238

Query: 226 LLFLGAGLFIYFRNQKGHSGLQPTGFLS 253
           LLFLGAGLFIYFRNQKGHSGLQPTGFLS
Sbjct: 239 LLFLGAGLFIYFRNQKGHSGLQPTGFLS 266


>gi|239748785 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-9 beta chain [Homo sapiens]
          Length = 266

 Score =  441 bits (1133), Expect = e-124
 Identities = 227/268 (84%), Positives = 234/268 (87%), Gaps = 17/268 (6%)

Query: 1   MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60
           MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFL Q K++CHFFNGTERV++L R  
Sbjct: 1   MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLKQDKFECHFFNGTERVRYLHRGI 60

Query: 61  YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------C-----LPDSFPL 105
           YNQEE VRFDSDVGEYRAVTELGRPVAE    Q D L          C     + +SF +
Sbjct: 61  YNQEENVRFDSDVGEYRAVTELGRPVAESWNSQKDFLERRRAEVDTVCRHNYGVGESFTV 120

Query: 106 PCFLLVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ 165
                VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ
Sbjct: 121 Q--RRVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ 178

Query: 166 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLG 225
           NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLG
Sbjct: 179 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLG 238

Query: 226 LLFLGAGLFIYFRNQKGHSGLQPTGFLS 253
           LLFLGAGLFIYFRNQKGHSGLQPTGFLS
Sbjct: 239 LLFLGAGLFIYFRNQKGHSGLQPTGFLS 266


>gi|155030211 major histocompatibility complex, class II, DR beta 1
           precursor [Homo sapiens]
          Length = 266

 Score =  431 bits (1108), Expect = e-121
 Identities = 218/266 (81%), Positives = 231/266 (86%), Gaps = 13/266 (4%)

Query: 1   MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60
           MVCLKLPGGSCM ALTVTLMVLSSPLAL+GDT+PRFLWQ K +CHFFNGTERV+FL+R F
Sbjct: 1   MVCLKLPGGSCMTALTVTLMVLSSPLALSGDTRPRFLWQPKRECHFFNGTERVRFLDRYF 60

Query: 61  YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------CLPDSFPLPCFLL 110
           YNQEE VRFDSDVGE+RAVTELGRP AE    Q D+L          C  +   +  F +
Sbjct: 61  YNQEESVRFDSDVGEFRAVTELGRPDAEYWNSQKDILEQARAAVDTYCRHNYGVVESFTV 120

Query: 111 ---VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 167
              V P+VTVYP+KTQPLQHHNLLVCSVSGFYPGSIEVRWF NGQEEKAG+VSTGLIQNG
Sbjct: 121 QRRVQPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFLNGQEEKAGMVSTGLIQNG 180

Query: 168 DWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLL 227
           DWTFQTLVMLETVPRSGEVYTCQVEHPSV SPLTVEWRARSESAQSKMLSGVGGFVLGLL
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL 240

Query: 228 FLGAGLFIYFRNQKGHSGLQPTGFLS 253
           FLGAGLFIYFRNQKGHSGLQPTGFLS
Sbjct: 241 FLGAGLFIYFRNQKGHSGLQPTGFLS 266


>gi|17986005 major histocompatibility complex, class II, DR beta 3
           precursor [Homo sapiens]
          Length = 266

 Score =  424 bits (1089), Expect = e-119
 Identities = 219/268 (81%), Positives = 231/268 (86%), Gaps = 17/268 (6%)

Query: 1   MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60
           MVCLKLPGGS +AALTVTLMVLSS LA AGDT+PRFL   K +CHFFNGTERV++L+R F
Sbjct: 1   MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYF 60

Query: 61  YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------C-----LPDSFPL 105
           +NQEEF+RFDSDVGEYRAVTELGRPVAE    Q DLL          C     + +SF +
Sbjct: 61  HNQEEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTV 120

Query: 106 PCFLLVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ 165
                VHP+VTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ
Sbjct: 121 Q--RRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ 178

Query: 166 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLG 225
           NGDWTFQTLVMLETVPRSGEVYTCQVEHPSV S LTVEWRARSESAQSKMLSGVGGFVLG
Sbjct: 179 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLG 238

Query: 226 LLFLGAGLFIYFRNQKGHSGLQPTGFLS 253
           LLFLGAGLFIYFRNQKGHSGLQPTGFLS
Sbjct: 239 LLFLGAGLFIYFRNQKGHSGLQPTGFLS 266


>gi|239748820 PREDICTED: hypothetical protein XP_002346811 [Homo
           sapiens]
          Length = 266

 Score =  423 bits (1087), Expect = e-119
 Identities = 217/268 (80%), Positives = 230/268 (85%), Gaps = 17/268 (6%)

Query: 1   MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60
           MVCL+LPGGSCMA LTVTLMVLSSPLALAGDT+PRFL + K++CHFFNGTERV+ LER F
Sbjct: 1   MVCLRLPGGSCMAVLTVTLMVLSSPLALAGDTRPRFLEEVKFECHFFNGTERVRLLERYF 60

Query: 61  YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------C-----LPDSFPL 105
           +NQEE VRFDSDVGE+RAVTELGRP AE    Q DLL          C     + +SF +
Sbjct: 61  HNQEENVRFDSDVGEFRAVTELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTV 120

Query: 106 PCFLLVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ 165
                VHP+VTVYP+KTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEK GVVSTGLI 
Sbjct: 121 Q--RRVHPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIH 178

Query: 166 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLG 225
           NGDWTFQTLVMLETVPRSGEVYTCQVEHPSV SPLTVEWRARSESAQSKMLSGVGGFVLG
Sbjct: 179 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLG 238

Query: 226 LLFLGAGLFIYFRNQKGHSGLQPTGFLS 253
           LLFLGAGLFIYFRNQKGHSGLQP GFLS
Sbjct: 239 LLFLGAGLFIYFRNQKGHSGLQPRGFLS 266


>gi|239740857 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 3 isoform 2 [Homo sapiens]
          Length = 266

 Score =  420 bits (1080), Expect = e-118
 Identities = 214/266 (80%), Positives = 227/266 (85%), Gaps = 13/266 (4%)

Query: 1   MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60
           MVCL+LPGGSCMA LTVTLMVLSSPLALAGDT+PRFL     +CHFFNGTERV++L+R F
Sbjct: 1   MVCLRLPGGSCMAVLTVTLMVLSSPLALAGDTRPRFLEYSTSECHFFNGTERVRYLDRYF 60

Query: 61  YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------CLPDSFPLPCFLL 110
           +NQEE VRFDSDVGE+RAVTELGRP AE    Q DLL          C  +   +  F +
Sbjct: 61  HNQEENVRFDSDVGEFRAVTELGRPDAEYWNSQKDLLEQKRGRVDNYCRHNYGVVESFTV 120

Query: 111 ---VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 167
              VHP+VTVYP+KTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEK GVVSTGLI NG
Sbjct: 121 QRRVHPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNG 180

Query: 168 DWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLL 227
           DWTFQTLVMLETVPRSGEVYTCQVEHPSV SPLTVEWRARSESAQSKMLSGVGGFVLGLL
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL 240

Query: 228 FLGAGLFIYFRNQKGHSGLQPTGFLS 253
           FLGAGLFIYFRNQKGHSGLQP GFLS
Sbjct: 241 FLGAGLFIYFRNQKGHSGLQPRGFLS 266


>gi|239740853 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 3 isoform 2 [Homo sapiens]
          Length = 266

 Score =  418 bits (1075), Expect = e-117
 Identities = 218/268 (81%), Positives = 228/268 (85%), Gaps = 17/268 (6%)

Query: 1   MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60
           MVCLKLPGGS +AALTVTLMVLSS LA AGDT+PRFL   K +CHFFNGTERV+FLER F
Sbjct: 1   MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELLKSECHFFNGTERVRFLERHF 60

Query: 61  YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------C-----LPDSFPL 105
           +NQEE+ RFDSDVGEYRAV ELGRP AE    Q DLL          C     + +SF +
Sbjct: 61  HNQEEYARFDSDVGEYRAVRELGRPDAEYWNSQKDLLEQKRGQVDNYCRHNYGVGESFTV 120

Query: 106 PCFLLVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ 165
                VHP+VTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ
Sbjct: 121 Q--RRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ 178

Query: 166 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLG 225
           NGDWTFQTLVMLETVPRSGEVYTCQVEHPSV SPLTVEW ARSESAQSKMLSGVGGFVLG
Sbjct: 179 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWSARSESAQSKMLSGVGGFVLG 238

Query: 226 LLFLGAGLFIYFRNQKGHSGLQPTGFLS 253
           LLFLGAGLFIYFRNQKGHSGLQPTGFLS
Sbjct: 239 LLFLGAGLFIYFRNQKGHSGLQPTGFLS 266


>gi|239740859 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 3 isoform 1 [Homo sapiens]
          Length = 267

 Score =  412 bits (1059), Expect = e-115
 Identities = 212/267 (79%), Positives = 226/267 (84%), Gaps = 14/267 (5%)

Query: 1   MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRF-LWQGKYKCHFFNGTERVQFLERL 59
           MVCL+LPGGSCMA LTVTLMVLSSPLALAGDT+ +  LW    +CHFFNGTERV++L+R 
Sbjct: 1   MVCLRLPGGSCMAVLTVTLMVLSSPLALAGDTRRKCTLWVPTSECHFFNGTERVRYLDRY 60

Query: 60  FYNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------CLPDSFPLPCFL 109
           F+NQEE VRFDSDVGE+RAVTELGRP AE    Q DLL          C  +   +  F 
Sbjct: 61  FHNQEENVRFDSDVGEFRAVTELGRPDAEYWNSQKDLLEQKRGRVDNYCRHNYGVVESFT 120

Query: 110 L---VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQN 166
           +   VHP+VTVYP+KTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEK GVVSTGLI N
Sbjct: 121 VQRRVHPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHN 180

Query: 167 GDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGL 226
           GDWTFQTLVMLETVPRSGEVYTCQVEHPSV SPLTVEWRARSESAQSKMLSGVGGFVLGL
Sbjct: 181 GDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGL 240

Query: 227 LFLGAGLFIYFRNQKGHSGLQPTGFLS 253
           LFLGAGLFIYFRNQKGHSGLQP GFLS
Sbjct: 241 LFLGAGLFIYFRNQKGHSGLQPRGFLS 267


>gi|239740855 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 3 isoform 1 [Homo sapiens]
          Length = 267

 Score =  411 bits (1057), Expect = e-115
 Identities = 216/269 (80%), Positives = 227/269 (84%), Gaps = 18/269 (6%)

Query: 1   MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRF-LWQGKYKCHFFNGTERVQFLERL 59
           MVCLKLPGGS +AALTVTLMVLSS LA AGDT+ +  LW  K +CHFFNGTERV+FLER 
Sbjct: 1   MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRRKSTLWLLKSECHFFNGTERVRFLERH 60

Query: 60  FYNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------C-----LPDSFP 104
           F+NQEE+ RFDSDVGEYRAV ELGRP AE    Q DLL          C     + +SF 
Sbjct: 61  FHNQEEYARFDSDVGEYRAVRELGRPDAEYWNSQKDLLEQKRGQVDNYCRHNYGVGESFT 120

Query: 105 LPCFLLVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLI 164
           +     VHP+VTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLI
Sbjct: 121 VQ--RRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLI 178

Query: 165 QNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVL 224
           QNGDWTFQTLVMLETVPRSGEVYTCQVEHPSV SPLTVEW ARSESAQSKMLSGVGGFVL
Sbjct: 179 QNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWSARSESAQSKMLSGVGGFVL 238

Query: 225 GLLFLGAGLFIYFRNQKGHSGLQPTGFLS 253
           GLLFLGAGLFIYFRNQKGHSGLQPTGFLS
Sbjct: 239 GLLFLGAGLFIYFRNQKGHSGLQPTGFLS 267


>gi|52630344 major histocompatibility complex, class II, DR beta 4
           precursor [Homo sapiens]
          Length = 266

 Score =  410 bits (1054), Expect = e-115
 Identities = 210/266 (78%), Positives = 224/266 (84%), Gaps = 13/266 (4%)

Query: 1   MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60
           MVCLKLPGGSCMAALTVTL VLSSPLALAGDTQPRFL Q K +CHF NGTERV  L R  
Sbjct: 1   MVCLKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYI 60

Query: 61  YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------CLPDSFPLPCFLL 110
           YNQEE+ R++SD+GEY+AVTELGRP AE    Q DLL          C  +   +  F +
Sbjct: 61  YNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTV 120

Query: 111 ---VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 167
              V P+VTVYP+KTQPLQHHNLLVCSV+GFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG
Sbjct: 121 QRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180

Query: 168 DWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLL 227
           DWTFQTLVMLETVPRSGEVYTCQVEHPS+MSPLTV+W ARSESAQSKMLSGVGGFVLGLL
Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLL 240

Query: 228 FLGAGLFIYFRNQKGHSGLQPTGFLS 253
           FLG GLFIYFRNQKGHSGLQPTG LS
Sbjct: 241 FLGTGLFIYFRNQKGHSGLQPTGLLS 266


>gi|18641375 major histocompatibility complex, class II, DR beta 5
           precursor [Homo sapiens]
          Length = 266

 Score =  409 bits (1051), Expect = e-114
 Identities = 212/268 (79%), Positives = 225/268 (83%), Gaps = 17/268 (6%)

Query: 1   MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60
           MVCLKLPGGS MA LTVTLMVLSSPLALAGDT+PRFL Q KY+CHFFNGTERV+FL R  
Sbjct: 1   MVCLKLPGGSYMAKLTVTLMVLSSPLALAGDTRPRFLQQDKYECHFFNGTERVRFLHRDI 60

Query: 61  YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------C-----LPDSFPL 105
           YNQEE +RFDSDVGEYRAVTELGRP AE    Q D L          C     + +SF +
Sbjct: 61  YNQEEDLRFDSDVGEYRAVTELGRPDAEYWNSQKDFLEDRRAAVDTYCRHNYGVGESFTV 120

Query: 106 PCFLLVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ 165
                V P+VTVYPA+TQ LQHHNLLVCSV+GFYPGSIEVRWFRN QEEKAGVVSTGLIQ
Sbjct: 121 Q--RRVEPKVTVYPARTQTLQHHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLIQ 178

Query: 166 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLG 225
           NGDWTFQTLVMLETVPRSGEVYTCQVEHPSV SPLTVEWRA+SESAQSKMLSGVGGFVLG
Sbjct: 179 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRAQSESAQSKMLSGVGGFVLG 238

Query: 226 LLFLGAGLFIYFRNQKGHSGLQPTGFLS 253
           LLFLGAGLFIYF+NQKGHSGL PTG +S
Sbjct: 239 LLFLGAGLFIYFKNQKGHSGLHPTGLVS 266


>gi|239740743 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain isoform 2 [Homo sapiens]
          Length = 264

 Score =  400 bits (1028), Expect = e-112
 Identities = 203/234 (86%), Positives = 207/234 (88%), Gaps = 17/234 (7%)

Query: 35  RFLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQG 94
           RFLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDSDVGEYRAVTELGRPVAE    Q 
Sbjct: 33  RFLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQK 92

Query: 95  DLL----------C-----LPDSFPLPCFLLVHPEVTVYPAKTQPLQHHNLLVCSVSGFY 139
           D+L          C     + +SF +     VHPEVTVYPAKTQPLQHHNLLVCSVSGFY
Sbjct: 93  DILEDRRGQVDTVCRHNYGVGESFTVQ--RRVHPEVTVYPAKTQPLQHHNLLVCSVSGFY 150

Query: 140 PGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSP 199
           PGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSP
Sbjct: 151 PGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSP 210

Query: 200 LTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS 253
           LTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS
Sbjct: 211 LTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS 264


>gi|239740693 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain isoform 2 [Homo sapiens]
          Length = 264

 Score =  400 bits (1028), Expect = e-112
 Identities = 203/234 (86%), Positives = 207/234 (88%), Gaps = 17/234 (7%)

Query: 35  RFLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQG 94
           RFLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDSDVGEYRAVTELGRPVAE    Q 
Sbjct: 33  RFLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQK 92

Query: 95  DLL----------C-----LPDSFPLPCFLLVHPEVTVYPAKTQPLQHHNLLVCSVSGFY 139
           D+L          C     + +SF +     VHPEVTVYPAKTQPLQHHNLLVCSVSGFY
Sbjct: 93  DILEDRRGQVDTVCRHNYGVGESFTVQ--RRVHPEVTVYPAKTQPLQHHNLLVCSVSGFY 150

Query: 140 PGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSP 199
           PGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSP
Sbjct: 151 PGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSP 210

Query: 200 LTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS 253
           LTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS
Sbjct: 211 LTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS 264


>gi|239758090 PREDICTED: major histocompatibility complex, class II,
           DR beta 4 [Homo sapiens]
          Length = 278

 Score =  347 bits (889), Expect = 7e-96
 Identities = 177/232 (76%), Positives = 191/232 (82%), Gaps = 13/232 (5%)

Query: 35  RFLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQG 94
           RFL Q K +CHF NGTERV  L R  YNQEE+ R++SD+GEY+AVTELGRP AE    Q 
Sbjct: 47  RFLEQAKCECHFLNGTERVWNLIRYIYNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQK 106

Query: 95  DLL----------CLPDSFPLPCFLL---VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPG 141
           DLL          C  +   +  F +   V P+VTVYP+KTQPLQHHNLLVCSV+GFYPG
Sbjct: 107 DLLERRRAEVDTYCRYNYGVVESFTVQRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPG 166

Query: 142 SIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLT 201
           SIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPS+MSPLT
Sbjct: 167 SIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLT 226

Query: 202 VEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS 253
           V+W ARSESAQSKMLSGVGGFVLGLLFLG GLFIYFRNQKGHSGLQPTG LS
Sbjct: 227 VQWSARSESAQSKMLSGVGGFVLGLLFLGTGLFIYFRNQKGHSGLQPTGLLS 278


>gi|239758095 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 [Homo sapiens]
          Length = 281

 Score =  286 bits (733), Expect = 9e-78
 Identities = 148/252 (58%), Positives = 181/252 (71%), Gaps = 13/252 (5%)

Query: 4   LKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLFYNQ 63
           L++PGG   A +T+ L +LS+P+A   D+   F++Q K  C+F NGTERV+ + R  YN+
Sbjct: 7   LRIPGGLRAATVTLMLSMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNR 66

Query: 64  EEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----CLPDSFPLPCFLL--------- 110
           EE VRFDSDVGE+RAVT LG P AE    Q D+L       D      + L         
Sbjct: 67  EEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRR 126

Query: 111 VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 170
           V P VT+ P++T+ L HHNLLVCSV+ FYP  I+VRWFRNGQEE AGVVST LI+NGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNGQEETAGVVSTPLIRNGDWT 186

Query: 171 FQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLG 230
           FQ LVMLE  P+ G+VYTC VEHPS+ SP+TVEWRA+SESAQSKMLSG+GGFVLGL+FLG
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246

Query: 231 AGLFIYFRNQKG 242
            GL I+ R+QKG
Sbjct: 247 LGLIIHHRSQKG 258


>gi|239740749 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 [Homo sapiens]
          Length = 281

 Score =  286 bits (733), Expect = 9e-78
 Identities = 148/252 (58%), Positives = 181/252 (71%), Gaps = 13/252 (5%)

Query: 4   LKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLFYNQ 63
           L++PGG   A +T+ L +LS+P+A   D+   F++Q K  C+F NGTERV+ + R  YN+
Sbjct: 7   LRIPGGLRAATVTLMLSMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNR 66

Query: 64  EEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----CLPDSFPLPCFLL--------- 110
           EE VRFDSDVGE+RAVT LG P AE    Q D+L       D      + L         
Sbjct: 67  EEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRR 126

Query: 111 VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 170
           V P VT+ P++T+ L HHNLLVCSV+ FYP  I+VRWFRNGQEE AGVVST LI+NGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNGQEETAGVVSTPLIRNGDWT 186

Query: 171 FQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLG 230
           FQ LVMLE  P+ G+VYTC VEHPS+ SP+TVEWRA+SESAQSKMLSG+GGFVLGL+FLG
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246

Query: 231 AGLFIYFRNQKG 242
            GL I+ R+QKG
Sbjct: 247 LGLIIHHRSQKG 258


>gi|239748788 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 isoform 2 [Homo sapiens]
          Length = 281

 Score =  285 bits (728), Expect = 3e-77
 Identities = 147/252 (58%), Positives = 181/252 (71%), Gaps = 13/252 (5%)

Query: 4   LKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLFYNQ 63
           L++PGG  +A +T+ L +LS+P+A   D+   F++Q K  C+F NGTERV+ + R  YN+
Sbjct: 7   LRIPGGLRVATVTLMLAMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNR 66

Query: 64  EEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----CLPDSFPLPCFLL--------- 110
           EE VRFDSDVGE+RAVT LG P AE    Q D+L       D      + L         
Sbjct: 67  EEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRR 126

Query: 111 VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 170
           V P VT+ P++T+ L HHNLLVCSV+ FYP  I+VRWFRN QEE AGVVST LI+NGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWT 186

Query: 171 FQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLG 230
           FQ LVMLE  P+ G+VYTC VEHPS+ SP+TVEWRA+SESAQSKMLSG+GGFVLGL+FLG
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246

Query: 231 AGLFIYFRNQKG 242
            GL I+ R+QKG
Sbjct: 247 LGLIIHHRSQKG 258


>gi|239740863 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 [Homo sapiens]
          Length = 281

 Score =  284 bits (726), Expect = 6e-77
 Identities = 147/252 (58%), Positives = 180/252 (71%), Gaps = 13/252 (5%)

Query: 4   LKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLFYNQ 63
           L++PGG   A +T+ L +LS+P+A   D+   F++Q K  C+F NGTERV+ + R  YN+
Sbjct: 7   LRIPGGLRAATVTLMLSMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNR 66

Query: 64  EEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----CLPDSFPLPCFLL--------- 110
           EE VRFDSDVGE+RAVT LG P AE    Q D+L       D      + L         
Sbjct: 67  EEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRR 126

Query: 111 VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 170
           V P VT+ P++T+ L HHNLLVCSV+ FYP  I+VRWFRN QEE AGVVST LI+NGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWT 186

Query: 171 FQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLG 230
           FQ LVMLE  P+ G+VYTC VEHPS+ SP+TVEWRA+SESAQSKMLSG+GGFVLGL+FLG
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246

Query: 231 AGLFIYFRNQKG 242
            GL I+ R+QKG
Sbjct: 247 LGLIIHHRSQKG 258


>gi|239513955 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 [Homo sapiens]
          Length = 281

 Score =  284 bits (726), Expect = 6e-77
 Identities = 147/252 (58%), Positives = 180/252 (71%), Gaps = 13/252 (5%)

Query: 4   LKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLFYNQ 63
           L++PGG   A +T+ L +LS+P+A   D+   F++Q K  C+F NGTERV+ + R  YN+
Sbjct: 7   LRIPGGLRAATVTLMLSMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNR 66

Query: 64  EEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----CLPDSFPLPCFLL--------- 110
           EE VRFDSDVGE+RAVT LG P AE    Q D+L       D      + L         
Sbjct: 67  EEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRR 126

Query: 111 VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 170
           V P VT+ P++T+ L HHNLLVCSV+ FYP  I+VRWFRN QEE AGVVST LI+NGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWT 186

Query: 171 FQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLG 230
           FQ LVMLE  P+ G+VYTC VEHPS+ SP+TVEWRA+SESAQSKMLSG+GGFVLGL+FLG
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246

Query: 231 AGLFIYFRNQKG 242
            GL I+ R+QKG
Sbjct: 247 LGLIIHHRSQKG 258


>gi|169168591 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 isoform 1 [Homo sapiens]
          Length = 261

 Score =  281 bits (718), Expect = 5e-76
 Identities = 145/252 (57%), Positives = 181/252 (71%), Gaps = 13/252 (5%)

Query: 4   LKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLFYNQ 63
           L++PGG  +A +T+ L +LS+P+A   D+   F++Q K  C+F NGTERV+ + R  YN+
Sbjct: 7   LRIPGGLRVATVTLMLAMLSTPVAEGRDSPEDFVFQFKGMCYFTNGTERVRGVTRYIYNR 66

Query: 64  EEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----CLPDSFPLPCFLL--------- 110
           EE+ RFDSDVG YRAVT LG P AE    Q ++L       D+     + L         
Sbjct: 67  EEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRASVDTVCRHNYQLELRTTLQRR 126

Query: 111 VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 170
           V P VT+ P++T+ L HHNLLVCSV+ FYP  I+VRWFRN QEE AGVVST LI+NGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWT 186

Query: 171 FQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLG 230
           FQ LVMLE  P+ G+VYTC VEHPS+ SP+TVEWRA+SESAQSKMLSG+GGFVLGL+FLG
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246

Query: 231 AGLFIYFRNQKG 242
            GL I+ R+QKG
Sbjct: 247 LGLIIHHRSQKG 258


>gi|150418002 major histocompatibility complex, class II, DQ beta 1
           precursor [Homo sapiens]
          Length = 261

 Score =  277 bits (708), Expect = 7e-75
 Identities = 147/252 (58%), Positives = 179/252 (71%), Gaps = 13/252 (5%)

Query: 4   LKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLFYNQ 63
           L++PG   +A +T+ L +LSS LA   D+   F++Q K  C+F NGTERV+ + R  YN+
Sbjct: 7   LRIPGDLRVATVTLMLAMLSSLLAEGRDSPEDFVFQFKGMCYFTNGTERVRLVTRYIYNR 66

Query: 64  EEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------CLPD---SFPLPCFLL 110
           EE+ RFDSDVG YRAVT  GRP AE    Q ++L          C  +   +F       
Sbjct: 67  EEYARFDSDVGVYRAVTPQGRPDAEYWNSQKEVLEGTRAELDTVCRHNYEVAFRGILQRR 126

Query: 111 VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 170
           V P VT+ P++T+ L HHNLLVCSV+ FYPG I+VRWFRN QEE AGVVST LI+NGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPGQIKVRWFRNDQEETAGVVSTPLIRNGDWT 186

Query: 171 FQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLG 230
           FQ LVMLE  P+ G+VYTC VEHPS+ SP+TVEWRA+SESAQSKMLSGVGGFVLGL+FLG
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGVGGFVLGLIFLG 246

Query: 231 AGLFIYFRNQKG 242
            GL I  R+QKG
Sbjct: 247 LGLIIRQRSQKG 258


>gi|239740920 PREDICTED: similar to major histocompatibility
           complex, class II, DQ beta 1 isoform 2 [Homo sapiens]
          Length = 261

 Score =  275 bits (704), Expect = 2e-74
 Identities = 143/252 (56%), Positives = 179/252 (71%), Gaps = 13/252 (5%)

Query: 4   LKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLFYNQ 63
           L++PGG  +A +T+ L +LS+P+A   D+   F++Q K  C+F NGTERV+ + R  YN+
Sbjct: 7   LRIPGGLRVATVTLMLAMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRGVTRYIYNR 66

Query: 64  EEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------CLPD-SFPLPCFLL-- 110
           EE+ RFDSDVG YRAVT LG P AE    Q ++L          C  +    L   L   
Sbjct: 67  EEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCRHNYQLELRTTLQRR 126

Query: 111 VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 170
           V P VT+ P++T+ L HHNLLVCSV+ FYP  I+VRWFRN QEE  GVVST LI+NGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPLIRNGDWT 186

Query: 171 FQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLG 230
           FQ LVMLE  P+ G+VYTC VEHPS+ +P+ VEWRA+SESAQSKMLSG+GGFVLGL+FLG
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246

Query: 231 AGLFIYFRNQKG 242
            GL I+ R+QKG
Sbjct: 247 LGLIIHHRSQKG 258


>gi|239740918 PREDICTED: similar to major histocompatibility
           complex, class II, DQ beta 1 isoform 1 [Homo sapiens]
          Length = 281

 Score =  275 bits (704), Expect = 2e-74
 Identities = 143/252 (56%), Positives = 179/252 (71%), Gaps = 13/252 (5%)

Query: 4   LKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLFYNQ 63
           L++PGG  +A +T+ L +LS+P+A   D+   F++Q K  C+F NGTERV+ + R  YN+
Sbjct: 7   LRIPGGLRVATVTLMLAMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRGVTRYIYNR 66

Query: 64  EEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------CLPD-SFPLPCFLL-- 110
           EE+ RFDSDVG YRAVT LG P AE    Q ++L          C  +    L   L   
Sbjct: 67  EEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCRHNYQLELRTTLQRR 126

Query: 111 VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 170
           V P VT+ P++T+ L HHNLLVCSV+ FYP  I+VRWFRN QEE  GVVST LI+NGDWT
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPLIRNGDWT 186

Query: 171 FQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLG 230
           FQ LVMLE  P+ G+VYTC VEHPS+ +P+ VEWRA+SESAQSKMLSG+GGFVLGL+FLG
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246

Query: 231 AGLFIYFRNQKG 242
            GL I+ R+QKG
Sbjct: 247 LGLIIHHRSQKG 258


>gi|24797076 major histocompatibility complex, class II, DP beta 1
           precursor [Homo sapiens]
          Length = 258

 Score =  275 bits (703), Expect = 3e-74
 Identities = 143/258 (55%), Positives = 178/258 (68%), Gaps = 15/258 (5%)

Query: 1   MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60
           M+ L++       ALT  LMVL + +     T   +L+QG+ +C+ FNGT+R  FLER  
Sbjct: 1   MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQR--FLERYI 58

Query: 61  YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----CLPDSF---------PLPC 107
           YN+EEF RFDSDVGE+RAVTELGRP AE    Q D+L     +PD           P+  
Sbjct: 59  YNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTL 118

Query: 108 FLLVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 167
              V P V V P+K  PLQHHNLLVC V+ FYPGSI+VRWF NGQEE AGVVST LI+NG
Sbjct: 119 QRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNG 178

Query: 168 DWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLL 227
           DWTFQ LVMLE  P+ G+VYTCQVEH S+ SP+TVEW+A+S+SA+SK L+G GGFVLGL+
Sbjct: 179 DWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLI 238

Query: 228 FLGAGLFIYFRNQKGHSG 245
             G G+F++ R++K   G
Sbjct: 239 ICGVGIFMHRRSKKVQRG 256


>gi|169217452 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-4 beta chain, partial [Homo sapiens]
          Length = 223

 Score =  260 bits (665), Expect = 7e-70
 Identities = 134/179 (74%), Positives = 146/179 (81%), Gaps = 17/179 (9%)

Query: 35  RFLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQG 94
           RFL Q K++CHFFNGTERV+FL+R FY+QEE+VRFDSDVGEYRAVTELGRP AE    Q 
Sbjct: 47  RFLEQVKHECHFFNGTERVRFLDRYFYHQEEYVRFDSDVGEYRAVTELGRPDAEYWNSQK 106

Query: 95  DLL----------C-----LPDSFPLPCFLLVHPEVTVYPAKTQPLQHHNLLVCSVSGFY 139
           DLL          C     + +SF +     V+PEVTVYPAKTQPLQHHNLLVCSV+GFY
Sbjct: 107 DLLEQKRAAVDTYCRHNYGVGESFTVQ--RRVYPEVTVYPAKTQPLQHHNLLVCSVNGFY 164

Query: 140 PGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMS 198
           PGSIEVRWFRNGQEEK GVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPS+ S
Sbjct: 165 PGSIEVRWFRNGQEEKTGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSLTS 223


>gi|169168671 PREDICTED: similar to MHC class II antigen [Homo
           sapiens]
          Length = 241

 Score =  258 bits (660), Expect = 3e-69
 Identities = 124/140 (88%), Positives = 130/140 (92%)

Query: 111 VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 170
           + P+ T+YPAKT+PL H N LVCSVSGFYPGSIEVRWF+NGQEEKA VVS GLIQNGDWT
Sbjct: 99  LQPKGTMYPAKTEPLHHRNPLVCSVSGFYPGSIEVRWFQNGQEEKAAVVSIGLIQNGDWT 158

Query: 171 FQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLG 230
           FQTLVMLETVPRSGEVYTCQVEHPSV SPLTVEW AR+ESAQSKMLSGVGGFVLGLLFLG
Sbjct: 159 FQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWSARTESAQSKMLSGVGGFVLGLLFLG 218

Query: 231 AGLFIYFRNQKGHSGLQPTG 250
            GLFIYFRNQKGHSGLQPTG
Sbjct: 219 TGLFIYFRNQKGHSGLQPTG 238


>gi|4504403 major histocompatibility complex, class II, DO beta
           precursor [Homo sapiens]
          Length = 273

 Score =  246 bits (629), Expect = 1e-65
 Identities = 130/252 (51%), Positives = 167/252 (66%), Gaps = 13/252 (5%)

Query: 12  MAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDS 71
           + AL V L  L S +    D+   F+ Q K  C+F NGTE+VQF+ R  +N EE+VRFDS
Sbjct: 9   VVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDS 68

Query: 72  DVGEYRAVTELGRPVAEQKTKQGDLL----------CLPD---SFPLPCFLLVHPEVTVY 118
           DVG + A+T+LG+P AEQ   + DLL          C  +     P      V PEVTVY
Sbjct: 69  DVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTVY 128

Query: 119 PAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLE 178
           P +T  L  HNLL CSV+GFYPG I+++WF NGQEE+AGV+STG I+NGDWTFQT+VMLE
Sbjct: 129 PERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVMLE 188

Query: 179 TVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFR 238
             P  G VYTC V+H S++SP++VEWRA+SE +  KMLSG+  F+LGL+FL  G+ I  R
Sbjct: 189 MTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQLR 248

Query: 239 NQKGHSGLQPTG 250
            QKG+   Q +G
Sbjct: 249 AQKGYVRTQMSG 260


>gi|169168589 PREDICTED: similar to MHC class II antigen [Homo
          sapiens]
          Length = 140

 Score =  146 bits (369), Expect = 1e-35
 Identities = 74/97 (76%), Positives = 80/97 (82%)

Query: 1  MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60
          MVCLKLPGGSCMAALTVTL VLSSPLALAGDTQPRFL Q K +CHF NGTERV  L R  
Sbjct: 1  MVCLKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYI 60

Query: 61 YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL 97
          YNQEE+ R++SD+GEY+AVTELGRP AE    Q DLL
Sbjct: 61 YNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLL 97


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.139    0.435 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,349,306
Number of Sequences: 37866
Number of extensions: 458721
Number of successful extensions: 1079
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 87
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 898
Number of HSP's gapped (non-prelim): 166
length of query: 253
length of database: 18,247,518
effective HSP length: 100
effective length of query: 153
effective length of database: 14,460,918
effective search space: 2212520454
effective search space used: 2212520454
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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