BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239758092 PREDICTED: similar to HLA class II histocompatibility antigen, DRB1-7 beta chain [Homo sapiens] (253 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239758092 PREDICTED: similar to HLA class II histocompatibili... 522 e-148 gi|239740745 PREDICTED: similar to HLA class II histocompatibili... 466 e-132 gi|239740695 PREDICTED: similar to HLA class II histocompatibili... 466 e-132 gi|239748785 PREDICTED: similar to HLA class II histocompatibili... 441 e-124 gi|155030211 major histocompatibility complex, class II, DR beta... 431 e-121 gi|17986005 major histocompatibility complex, class II, DR beta ... 424 e-119 gi|239748820 PREDICTED: hypothetical protein XP_002346811 [Homo ... 423 e-119 gi|239740857 PREDICTED: similar to major histocompatibility comp... 420 e-118 gi|239740853 PREDICTED: similar to major histocompatibility comp... 418 e-117 gi|239740859 PREDICTED: similar to major histocompatibility comp... 412 e-115 gi|239740855 PREDICTED: similar to major histocompatibility comp... 411 e-115 gi|52630344 major histocompatibility complex, class II, DR beta ... 410 e-115 gi|18641375 major histocompatibility complex, class II, DR beta ... 409 e-114 gi|239740743 PREDICTED: similar to HLA class II histocompatibili... 400 e-112 gi|239740693 PREDICTED: similar to HLA class II histocompatibili... 400 e-112 gi|239758090 PREDICTED: major histocompatibility complex, class ... 347 7e-96 gi|239758095 PREDICTED: similar to major histocompatibility comp... 286 9e-78 gi|239740749 PREDICTED: similar to major histocompatibility comp... 286 9e-78 gi|239748788 PREDICTED: similar to major histocompatibility comp... 285 3e-77 gi|239740863 PREDICTED: similar to major histocompatibility comp... 284 6e-77 gi|239513955 PREDICTED: similar to major histocompatibility comp... 284 6e-77 gi|169168591 PREDICTED: similar to major histocompatibility comp... 281 5e-76 gi|150418002 major histocompatibility complex, class II, DQ beta... 277 7e-75 gi|239740920 PREDICTED: similar to major histocompatibility comp... 275 2e-74 gi|239740918 PREDICTED: similar to major histocompatibility comp... 275 2e-74 gi|24797076 major histocompatibility complex, class II, DP beta ... 275 3e-74 gi|169217452 PREDICTED: similar to HLA class II histocompatibili... 260 7e-70 gi|169168671 PREDICTED: similar to MHC class II antigen [Homo sa... 258 3e-69 gi|4504403 major histocompatibility complex, class II, DO beta p... 246 1e-65 gi|169168589 PREDICTED: similar to MHC class II antigen [Homo sa... 146 1e-35 >gi|239758092 PREDICTED: similar to HLA class II histocompatibility antigen, DRB1-7 beta chain [Homo sapiens] Length = 253 Score = 522 bits (1344), Expect = e-148 Identities = 253/253 (100%), Positives = 253/253 (100%) Query: 1 MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60 MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF Sbjct: 1 MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60 Query: 61 YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLLCLPDSFPLPCFLLVHPEVTVYPA 120 YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLLCLPDSFPLPCFLLVHPEVTVYPA Sbjct: 61 YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLLCLPDSFPLPCFLLVHPEVTVYPA 120 Query: 121 KTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETV 180 KTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETV Sbjct: 121 KTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETV 180 Query: 181 PRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQ 240 PRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQ Sbjct: 181 PRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQ 240 Query: 241 KGHSGLQPTGFLS 253 KGHSGLQPTGFLS Sbjct: 241 KGHSGLQPTGFLS 253 >gi|239740745 PREDICTED: similar to HLA class II histocompatibility antigen, DRB1-7 beta chain isoform 1 [Homo sapiens] Length = 266 Score = 466 bits (1199), Expect = e-132 Identities = 237/268 (88%), Positives = 241/268 (89%), Gaps = 17/268 (6%) Query: 1 MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60 MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF Sbjct: 1 MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60 Query: 61 YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------C-----LPDSFPL 105 YNQEEFVRFDSDVGEYRAVTELGRPVAE Q D+L C + +SF + Sbjct: 61 YNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQKDILEDRRGQVDTVCRHNYGVGESFTV 120 Query: 106 PCFLLVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ 165 VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ Sbjct: 121 Q--RRVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ 178 Query: 166 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLG 225 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLG Sbjct: 179 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLG 238 Query: 226 LLFLGAGLFIYFRNQKGHSGLQPTGFLS 253 LLFLGAGLFIYFRNQKGHSGLQPTGFLS Sbjct: 239 LLFLGAGLFIYFRNQKGHSGLQPTGFLS 266 >gi|239740695 PREDICTED: similar to HLA class II histocompatibility antigen, DRB1-7 beta chain isoform 1 [Homo sapiens] Length = 266 Score = 466 bits (1199), Expect = e-132 Identities = 237/268 (88%), Positives = 241/268 (89%), Gaps = 17/268 (6%) Query: 1 MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60 MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF Sbjct: 1 MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60 Query: 61 YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------C-----LPDSFPL 105 YNQEEFVRFDSDVGEYRAVTELGRPVAE Q D+L C + +SF + Sbjct: 61 YNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQKDILEDRRGQVDTVCRHNYGVGESFTV 120 Query: 106 PCFLLVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ 165 VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ Sbjct: 121 Q--RRVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ 178 Query: 166 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLG 225 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLG Sbjct: 179 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLG 238 Query: 226 LLFLGAGLFIYFRNQKGHSGLQPTGFLS 253 LLFLGAGLFIYFRNQKGHSGLQPTGFLS Sbjct: 239 LLFLGAGLFIYFRNQKGHSGLQPTGFLS 266 >gi|239748785 PREDICTED: similar to HLA class II histocompatibility antigen, DRB1-9 beta chain [Homo sapiens] Length = 266 Score = 441 bits (1133), Expect = e-124 Identities = 227/268 (84%), Positives = 234/268 (87%), Gaps = 17/268 (6%) Query: 1 MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60 MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFL Q K++CHFFNGTERV++L R Sbjct: 1 MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLKQDKFECHFFNGTERVRYLHRGI 60 Query: 61 YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------C-----LPDSFPL 105 YNQEE VRFDSDVGEYRAVTELGRPVAE Q D L C + +SF + Sbjct: 61 YNQEENVRFDSDVGEYRAVTELGRPVAESWNSQKDFLERRRAEVDTVCRHNYGVGESFTV 120 Query: 106 PCFLLVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ 165 VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ Sbjct: 121 Q--RRVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ 178 Query: 166 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLG 225 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLG Sbjct: 179 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLG 238 Query: 226 LLFLGAGLFIYFRNQKGHSGLQPTGFLS 253 LLFLGAGLFIYFRNQKGHSGLQPTGFLS Sbjct: 239 LLFLGAGLFIYFRNQKGHSGLQPTGFLS 266 >gi|155030211 major histocompatibility complex, class II, DR beta 1 precursor [Homo sapiens] Length = 266 Score = 431 bits (1108), Expect = e-121 Identities = 218/266 (81%), Positives = 231/266 (86%), Gaps = 13/266 (4%) Query: 1 MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60 MVCLKLPGGSCM ALTVTLMVLSSPLAL+GDT+PRFLWQ K +CHFFNGTERV+FL+R F Sbjct: 1 MVCLKLPGGSCMTALTVTLMVLSSPLALSGDTRPRFLWQPKRECHFFNGTERVRFLDRYF 60 Query: 61 YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------CLPDSFPLPCFLL 110 YNQEE VRFDSDVGE+RAVTELGRP AE Q D+L C + + F + Sbjct: 61 YNQEESVRFDSDVGEFRAVTELGRPDAEYWNSQKDILEQARAAVDTYCRHNYGVVESFTV 120 Query: 111 ---VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 167 V P+VTVYP+KTQPLQHHNLLVCSVSGFYPGSIEVRWF NGQEEKAG+VSTGLIQNG Sbjct: 121 QRRVQPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFLNGQEEKAGMVSTGLIQNG 180 Query: 168 DWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLL 227 DWTFQTLVMLETVPRSGEVYTCQVEHPSV SPLTVEWRARSESAQSKMLSGVGGFVLGLL Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL 240 Query: 228 FLGAGLFIYFRNQKGHSGLQPTGFLS 253 FLGAGLFIYFRNQKGHSGLQPTGFLS Sbjct: 241 FLGAGLFIYFRNQKGHSGLQPTGFLS 266 >gi|17986005 major histocompatibility complex, class II, DR beta 3 precursor [Homo sapiens] Length = 266 Score = 424 bits (1089), Expect = e-119 Identities = 219/268 (81%), Positives = 231/268 (86%), Gaps = 17/268 (6%) Query: 1 MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60 MVCLKLPGGS +AALTVTLMVLSS LA AGDT+PRFL K +CHFFNGTERV++L+R F Sbjct: 1 MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELRKSECHFFNGTERVRYLDRYF 60 Query: 61 YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------C-----LPDSFPL 105 +NQEEF+RFDSDVGEYRAVTELGRPVAE Q DLL C + +SF + Sbjct: 61 HNQEEFLRFDSDVGEYRAVTELGRPVAESWNSQKDLLEQKRGRVDNYCRHNYGVGESFTV 120 Query: 106 PCFLLVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ 165 VHP+VTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ Sbjct: 121 Q--RRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ 178 Query: 166 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLG 225 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSV S LTVEWRARSESAQSKMLSGVGGFVLG Sbjct: 179 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSGVGGFVLG 238 Query: 226 LLFLGAGLFIYFRNQKGHSGLQPTGFLS 253 LLFLGAGLFIYFRNQKGHSGLQPTGFLS Sbjct: 239 LLFLGAGLFIYFRNQKGHSGLQPTGFLS 266 >gi|239748820 PREDICTED: hypothetical protein XP_002346811 [Homo sapiens] Length = 266 Score = 423 bits (1087), Expect = e-119 Identities = 217/268 (80%), Positives = 230/268 (85%), Gaps = 17/268 (6%) Query: 1 MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60 MVCL+LPGGSCMA LTVTLMVLSSPLALAGDT+PRFL + K++CHFFNGTERV+ LER F Sbjct: 1 MVCLRLPGGSCMAVLTVTLMVLSSPLALAGDTRPRFLEEVKFECHFFNGTERVRLLERYF 60 Query: 61 YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------C-----LPDSFPL 105 +NQEE VRFDSDVGE+RAVTELGRP AE Q DLL C + +SF + Sbjct: 61 HNQEENVRFDSDVGEFRAVTELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTV 120 Query: 106 PCFLLVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ 165 VHP+VTVYP+KTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEK GVVSTGLI Sbjct: 121 Q--RRVHPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIH 178 Query: 166 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLG 225 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSV SPLTVEWRARSESAQSKMLSGVGGFVLG Sbjct: 179 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLG 238 Query: 226 LLFLGAGLFIYFRNQKGHSGLQPTGFLS 253 LLFLGAGLFIYFRNQKGHSGLQP GFLS Sbjct: 239 LLFLGAGLFIYFRNQKGHSGLQPRGFLS 266 >gi|239740857 PREDICTED: similar to major histocompatibility complex, class II, DR beta 3 isoform 2 [Homo sapiens] Length = 266 Score = 420 bits (1080), Expect = e-118 Identities = 214/266 (80%), Positives = 227/266 (85%), Gaps = 13/266 (4%) Query: 1 MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60 MVCL+LPGGSCMA LTVTLMVLSSPLALAGDT+PRFL +CHFFNGTERV++L+R F Sbjct: 1 MVCLRLPGGSCMAVLTVTLMVLSSPLALAGDTRPRFLEYSTSECHFFNGTERVRYLDRYF 60 Query: 61 YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------CLPDSFPLPCFLL 110 +NQEE VRFDSDVGE+RAVTELGRP AE Q DLL C + + F + Sbjct: 61 HNQEENVRFDSDVGEFRAVTELGRPDAEYWNSQKDLLEQKRGRVDNYCRHNYGVVESFTV 120 Query: 111 ---VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 167 VHP+VTVYP+KTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEK GVVSTGLI NG Sbjct: 121 QRRVHPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHNG 180 Query: 168 DWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLL 227 DWTFQTLVMLETVPRSGEVYTCQVEHPSV SPLTVEWRARSESAQSKMLSGVGGFVLGLL Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGLL 240 Query: 228 FLGAGLFIYFRNQKGHSGLQPTGFLS 253 FLGAGLFIYFRNQKGHSGLQP GFLS Sbjct: 241 FLGAGLFIYFRNQKGHSGLQPRGFLS 266 >gi|239740853 PREDICTED: similar to major histocompatibility complex, class II, DR beta 3 isoform 2 [Homo sapiens] Length = 266 Score = 418 bits (1075), Expect = e-117 Identities = 218/268 (81%), Positives = 228/268 (85%), Gaps = 17/268 (6%) Query: 1 MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60 MVCLKLPGGS +AALTVTLMVLSS LA AGDT+PRFL K +CHFFNGTERV+FLER F Sbjct: 1 MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRPRFLELLKSECHFFNGTERVRFLERHF 60 Query: 61 YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------C-----LPDSFPL 105 +NQEE+ RFDSDVGEYRAV ELGRP AE Q DLL C + +SF + Sbjct: 61 HNQEEYARFDSDVGEYRAVRELGRPDAEYWNSQKDLLEQKRGQVDNYCRHNYGVGESFTV 120 Query: 106 PCFLLVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ 165 VHP+VTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ Sbjct: 121 Q--RRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ 178 Query: 166 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLG 225 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSV SPLTVEW ARSESAQSKMLSGVGGFVLG Sbjct: 179 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWSARSESAQSKMLSGVGGFVLG 238 Query: 226 LLFLGAGLFIYFRNQKGHSGLQPTGFLS 253 LLFLGAGLFIYFRNQKGHSGLQPTGFLS Sbjct: 239 LLFLGAGLFIYFRNQKGHSGLQPTGFLS 266 >gi|239740859 PREDICTED: similar to major histocompatibility complex, class II, DR beta 3 isoform 1 [Homo sapiens] Length = 267 Score = 412 bits (1059), Expect = e-115 Identities = 212/267 (79%), Positives = 226/267 (84%), Gaps = 14/267 (5%) Query: 1 MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRF-LWQGKYKCHFFNGTERVQFLERL 59 MVCL+LPGGSCMA LTVTLMVLSSPLALAGDT+ + LW +CHFFNGTERV++L+R Sbjct: 1 MVCLRLPGGSCMAVLTVTLMVLSSPLALAGDTRRKCTLWVPTSECHFFNGTERVRYLDRY 60 Query: 60 FYNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------CLPDSFPLPCFL 109 F+NQEE VRFDSDVGE+RAVTELGRP AE Q DLL C + + F Sbjct: 61 FHNQEENVRFDSDVGEFRAVTELGRPDAEYWNSQKDLLEQKRGRVDNYCRHNYGVVESFT 120 Query: 110 L---VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQN 166 + VHP+VTVYP+KTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEK GVVSTGLI N Sbjct: 121 VQRRVHPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGLIHN 180 Query: 167 GDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGL 226 GDWTFQTLVMLETVPRSGEVYTCQVEHPSV SPLTVEWRARSESAQSKMLSGVGGFVLGL Sbjct: 181 GDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSGVGGFVLGL 240 Query: 227 LFLGAGLFIYFRNQKGHSGLQPTGFLS 253 LFLGAGLFIYFRNQKGHSGLQP GFLS Sbjct: 241 LFLGAGLFIYFRNQKGHSGLQPRGFLS 267 >gi|239740855 PREDICTED: similar to major histocompatibility complex, class II, DR beta 3 isoform 1 [Homo sapiens] Length = 267 Score = 411 bits (1057), Expect = e-115 Identities = 216/269 (80%), Positives = 227/269 (84%), Gaps = 18/269 (6%) Query: 1 MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRF-LWQGKYKCHFFNGTERVQFLERL 59 MVCLKLPGGS +AALTVTLMVLSS LA AGDT+ + LW K +CHFFNGTERV+FLER Sbjct: 1 MVCLKLPGGSSLAALTVTLMVLSSRLAFAGDTRRKSTLWLLKSECHFFNGTERVRFLERH 60 Query: 60 FYNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------C-----LPDSFP 104 F+NQEE+ RFDSDVGEYRAV ELGRP AE Q DLL C + +SF Sbjct: 61 FHNQEEYARFDSDVGEYRAVRELGRPDAEYWNSQKDLLEQKRGQVDNYCRHNYGVGESFT 120 Query: 105 LPCFLLVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLI 164 + VHP+VTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLI Sbjct: 121 VQ--RRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLI 178 Query: 165 QNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVL 224 QNGDWTFQTLVMLETVPRSGEVYTCQVEHPSV SPLTVEW ARSESAQSKMLSGVGGFVL Sbjct: 179 QNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWSARSESAQSKMLSGVGGFVL 238 Query: 225 GLLFLGAGLFIYFRNQKGHSGLQPTGFLS 253 GLLFLGAGLFIYFRNQKGHSGLQPTGFLS Sbjct: 239 GLLFLGAGLFIYFRNQKGHSGLQPTGFLS 267 >gi|52630344 major histocompatibility complex, class II, DR beta 4 precursor [Homo sapiens] Length = 266 Score = 410 bits (1054), Expect = e-115 Identities = 210/266 (78%), Positives = 224/266 (84%), Gaps = 13/266 (4%) Query: 1 MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60 MVCLKLPGGSCMAALTVTL VLSSPLALAGDTQPRFL Q K +CHF NGTERV L R Sbjct: 1 MVCLKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYI 60 Query: 61 YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------CLPDSFPLPCFLL 110 YNQEE+ R++SD+GEY+AVTELGRP AE Q DLL C + + F + Sbjct: 61 YNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLLERRRAEVDTYCRYNYGVVESFTV 120 Query: 111 ---VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 167 V P+VTVYP+KTQPLQHHNLLVCSV+GFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG Sbjct: 121 QRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 180 Query: 168 DWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLL 227 DWTFQTLVMLETVPRSGEVYTCQVEHPS+MSPLTV+W ARSESAQSKMLSGVGGFVLGLL Sbjct: 181 DWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKMLSGVGGFVLGLL 240 Query: 228 FLGAGLFIYFRNQKGHSGLQPTGFLS 253 FLG GLFIYFRNQKGHSGLQPTG LS Sbjct: 241 FLGTGLFIYFRNQKGHSGLQPTGLLS 266 >gi|18641375 major histocompatibility complex, class II, DR beta 5 precursor [Homo sapiens] Length = 266 Score = 409 bits (1051), Expect = e-114 Identities = 212/268 (79%), Positives = 225/268 (83%), Gaps = 17/268 (6%) Query: 1 MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60 MVCLKLPGGS MA LTVTLMVLSSPLALAGDT+PRFL Q KY+CHFFNGTERV+FL R Sbjct: 1 MVCLKLPGGSYMAKLTVTLMVLSSPLALAGDTRPRFLQQDKYECHFFNGTERVRFLHRDI 60 Query: 61 YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------C-----LPDSFPL 105 YNQEE +RFDSDVGEYRAVTELGRP AE Q D L C + +SF + Sbjct: 61 YNQEEDLRFDSDVGEYRAVTELGRPDAEYWNSQKDFLEDRRAAVDTYCRHNYGVGESFTV 120 Query: 106 PCFLLVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQ 165 V P+VTVYPA+TQ LQHHNLLVCSV+GFYPGSIEVRWFRN QEEKAGVVSTGLIQ Sbjct: 121 Q--RRVEPKVTVYPARTQTLQHHNLLVCSVNGFYPGSIEVRWFRNSQEEKAGVVSTGLIQ 178 Query: 166 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLG 225 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSV SPLTVEWRA+SESAQSKMLSGVGGFVLG Sbjct: 179 NGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRAQSESAQSKMLSGVGGFVLG 238 Query: 226 LLFLGAGLFIYFRNQKGHSGLQPTGFLS 253 LLFLGAGLFIYF+NQKGHSGL PTG +S Sbjct: 239 LLFLGAGLFIYFKNQKGHSGLHPTGLVS 266 >gi|239740743 PREDICTED: similar to HLA class II histocompatibility antigen, DRB1-7 beta chain isoform 2 [Homo sapiens] Length = 264 Score = 400 bits (1028), Expect = e-112 Identities = 203/234 (86%), Positives = 207/234 (88%), Gaps = 17/234 (7%) Query: 35 RFLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQG 94 RFLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDSDVGEYRAVTELGRPVAE Q Sbjct: 33 RFLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQK 92 Query: 95 DLL----------C-----LPDSFPLPCFLLVHPEVTVYPAKTQPLQHHNLLVCSVSGFY 139 D+L C + +SF + VHPEVTVYPAKTQPLQHHNLLVCSVSGFY Sbjct: 93 DILEDRRGQVDTVCRHNYGVGESFTVQ--RRVHPEVTVYPAKTQPLQHHNLLVCSVSGFY 150 Query: 140 PGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSP 199 PGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSP Sbjct: 151 PGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSP 210 Query: 200 LTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS 253 LTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS Sbjct: 211 LTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS 264 >gi|239740693 PREDICTED: similar to HLA class II histocompatibility antigen, DRB1-7 beta chain isoform 2 [Homo sapiens] Length = 264 Score = 400 bits (1028), Expect = e-112 Identities = 203/234 (86%), Positives = 207/234 (88%), Gaps = 17/234 (7%) Query: 35 RFLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQG 94 RFLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDSDVGEYRAVTELGRPVAE Q Sbjct: 33 RFLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDSDVGEYRAVTELGRPVAESWNSQK 92 Query: 95 DLL----------C-----LPDSFPLPCFLLVHPEVTVYPAKTQPLQHHNLLVCSVSGFY 139 D+L C + +SF + VHPEVTVYPAKTQPLQHHNLLVCSVSGFY Sbjct: 93 DILEDRRGQVDTVCRHNYGVGESFTVQ--RRVHPEVTVYPAKTQPLQHHNLLVCSVSGFY 150 Query: 140 PGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSP 199 PGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSP Sbjct: 151 PGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSP 210 Query: 200 LTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS 253 LTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS Sbjct: 211 LTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS 264 >gi|239758090 PREDICTED: major histocompatibility complex, class II, DR beta 4 [Homo sapiens] Length = 278 Score = 347 bits (889), Expect = 7e-96 Identities = 177/232 (76%), Positives = 191/232 (82%), Gaps = 13/232 (5%) Query: 35 RFLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQG 94 RFL Q K +CHF NGTERV L R YNQEE+ R++SD+GEY+AVTELGRP AE Q Sbjct: 47 RFLEQAKCECHFLNGTERVWNLIRYIYNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQK 106 Query: 95 DLL----------CLPDSFPLPCFLL---VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPG 141 DLL C + + F + V P+VTVYP+KTQPLQHHNLLVCSV+GFYPG Sbjct: 107 DLLERRRAEVDTYCRYNYGVVESFTVQRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPG 166 Query: 142 SIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLT 201 SIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPS+MSPLT Sbjct: 167 SIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLT 226 Query: 202 VEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSGLQPTGFLS 253 V+W ARSESAQSKMLSGVGGFVLGLLFLG GLFIYFRNQKGHSGLQPTG LS Sbjct: 227 VQWSARSESAQSKMLSGVGGFVLGLLFLGTGLFIYFRNQKGHSGLQPTGLLS 278 >gi|239758095 PREDICTED: similar to major histocompatibility complex, class II, DR beta 5 [Homo sapiens] Length = 281 Score = 286 bits (733), Expect = 9e-78 Identities = 148/252 (58%), Positives = 181/252 (71%), Gaps = 13/252 (5%) Query: 4 LKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLFYNQ 63 L++PGG A +T+ L +LS+P+A D+ F++Q K C+F NGTERV+ + R YN+ Sbjct: 7 LRIPGGLRAATVTLMLSMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNR 66 Query: 64 EEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----CLPDSFPLPCFLL--------- 110 EE VRFDSDVGE+RAVT LG P AE Q D+L D + L Sbjct: 67 EEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRR 126 Query: 111 VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 170 V P VT+ P++T+ L HHNLLVCSV+ FYP I+VRWFRNGQEE AGVVST LI+NGDWT Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNGQEETAGVVSTPLIRNGDWT 186 Query: 171 FQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLG 230 FQ LVMLE P+ G+VYTC VEHPS+ SP+TVEWRA+SESAQSKMLSG+GGFVLGL+FLG Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246 Query: 231 AGLFIYFRNQKG 242 GL I+ R+QKG Sbjct: 247 LGLIIHHRSQKG 258 >gi|239740749 PREDICTED: similar to major histocompatibility complex, class II, DR beta 5 [Homo sapiens] Length = 281 Score = 286 bits (733), Expect = 9e-78 Identities = 148/252 (58%), Positives = 181/252 (71%), Gaps = 13/252 (5%) Query: 4 LKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLFYNQ 63 L++PGG A +T+ L +LS+P+A D+ F++Q K C+F NGTERV+ + R YN+ Sbjct: 7 LRIPGGLRAATVTLMLSMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNR 66 Query: 64 EEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----CLPDSFPLPCFLL--------- 110 EE VRFDSDVGE+RAVT LG P AE Q D+L D + L Sbjct: 67 EEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRR 126 Query: 111 VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 170 V P VT+ P++T+ L HHNLLVCSV+ FYP I+VRWFRNGQEE AGVVST LI+NGDWT Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNGQEETAGVVSTPLIRNGDWT 186 Query: 171 FQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLG 230 FQ LVMLE P+ G+VYTC VEHPS+ SP+TVEWRA+SESAQSKMLSG+GGFVLGL+FLG Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246 Query: 231 AGLFIYFRNQKG 242 GL I+ R+QKG Sbjct: 247 LGLIIHHRSQKG 258 >gi|239748788 PREDICTED: similar to major histocompatibility complex, class II, DR beta 5 isoform 2 [Homo sapiens] Length = 281 Score = 285 bits (728), Expect = 3e-77 Identities = 147/252 (58%), Positives = 181/252 (71%), Gaps = 13/252 (5%) Query: 4 LKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLFYNQ 63 L++PGG +A +T+ L +LS+P+A D+ F++Q K C+F NGTERV+ + R YN+ Sbjct: 7 LRIPGGLRVATVTLMLAMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNR 66 Query: 64 EEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----CLPDSFPLPCFLL--------- 110 EE VRFDSDVGE+RAVT LG P AE Q D+L D + L Sbjct: 67 EEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRR 126 Query: 111 VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 170 V P VT+ P++T+ L HHNLLVCSV+ FYP I+VRWFRN QEE AGVVST LI+NGDWT Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWT 186 Query: 171 FQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLG 230 FQ LVMLE P+ G+VYTC VEHPS+ SP+TVEWRA+SESAQSKMLSG+GGFVLGL+FLG Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246 Query: 231 AGLFIYFRNQKG 242 GL I+ R+QKG Sbjct: 247 LGLIIHHRSQKG 258 >gi|239740863 PREDICTED: similar to major histocompatibility complex, class II, DR beta 5 [Homo sapiens] Length = 281 Score = 284 bits (726), Expect = 6e-77 Identities = 147/252 (58%), Positives = 180/252 (71%), Gaps = 13/252 (5%) Query: 4 LKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLFYNQ 63 L++PGG A +T+ L +LS+P+A D+ F++Q K C+F NGTERV+ + R YN+ Sbjct: 7 LRIPGGLRAATVTLMLSMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNR 66 Query: 64 EEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----CLPDSFPLPCFLL--------- 110 EE VRFDSDVGE+RAVT LG P AE Q D+L D + L Sbjct: 67 EEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRR 126 Query: 111 VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 170 V P VT+ P++T+ L HHNLLVCSV+ FYP I+VRWFRN QEE AGVVST LI+NGDWT Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWT 186 Query: 171 FQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLG 230 FQ LVMLE P+ G+VYTC VEHPS+ SP+TVEWRA+SESAQSKMLSG+GGFVLGL+FLG Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246 Query: 231 AGLFIYFRNQKG 242 GL I+ R+QKG Sbjct: 247 LGLIIHHRSQKG 258 >gi|239513955 PREDICTED: similar to major histocompatibility complex, class II, DR beta 5 [Homo sapiens] Length = 281 Score = 284 bits (726), Expect = 6e-77 Identities = 147/252 (58%), Positives = 180/252 (71%), Gaps = 13/252 (5%) Query: 4 LKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLFYNQ 63 L++PGG A +T+ L +LS+P+A D+ F++Q K C+F NGTERV+ + R YN+ Sbjct: 7 LRIPGGLRAATVTLMLSMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRLVSRSIYNR 66 Query: 64 EEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----CLPDSFPLPCFLL--------- 110 EE VRFDSDVGE+RAVT LG P AE Q D+L D + L Sbjct: 67 EEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRR 126 Query: 111 VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 170 V P VT+ P++T+ L HHNLLVCSV+ FYP I+VRWFRN QEE AGVVST LI+NGDWT Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWT 186 Query: 171 FQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLG 230 FQ LVMLE P+ G+VYTC VEHPS+ SP+TVEWRA+SESAQSKMLSG+GGFVLGL+FLG Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246 Query: 231 AGLFIYFRNQKG 242 GL I+ R+QKG Sbjct: 247 LGLIIHHRSQKG 258 >gi|169168591 PREDICTED: similar to major histocompatibility complex, class II, DR beta 5 isoform 1 [Homo sapiens] Length = 261 Score = 281 bits (718), Expect = 5e-76 Identities = 145/252 (57%), Positives = 181/252 (71%), Gaps = 13/252 (5%) Query: 4 LKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLFYNQ 63 L++PGG +A +T+ L +LS+P+A D+ F++Q K C+F NGTERV+ + R YN+ Sbjct: 7 LRIPGGLRVATVTLMLAMLSTPVAEGRDSPEDFVFQFKGMCYFTNGTERVRGVTRYIYNR 66 Query: 64 EEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----CLPDSFPLPCFLL--------- 110 EE+ RFDSDVG YRAVT LG P AE Q ++L D+ + L Sbjct: 67 EEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRASVDTVCRHNYQLELRTTLQRR 126 Query: 111 VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 170 V P VT+ P++T+ L HHNLLVCSV+ FYP I+VRWFRN QEE AGVVST LI+NGDWT Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWT 186 Query: 171 FQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLG 230 FQ LVMLE P+ G+VYTC VEHPS+ SP+TVEWRA+SESAQSKMLSG+GGFVLGL+FLG Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246 Query: 231 AGLFIYFRNQKG 242 GL I+ R+QKG Sbjct: 247 LGLIIHHRSQKG 258 >gi|150418002 major histocompatibility complex, class II, DQ beta 1 precursor [Homo sapiens] Length = 261 Score = 277 bits (708), Expect = 7e-75 Identities = 147/252 (58%), Positives = 179/252 (71%), Gaps = 13/252 (5%) Query: 4 LKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLFYNQ 63 L++PG +A +T+ L +LSS LA D+ F++Q K C+F NGTERV+ + R YN+ Sbjct: 7 LRIPGDLRVATVTLMLAMLSSLLAEGRDSPEDFVFQFKGMCYFTNGTERVRLVTRYIYNR 66 Query: 64 EEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------CLPD---SFPLPCFLL 110 EE+ RFDSDVG YRAVT GRP AE Q ++L C + +F Sbjct: 67 EEYARFDSDVGVYRAVTPQGRPDAEYWNSQKEVLEGTRAELDTVCRHNYEVAFRGILQRR 126 Query: 111 VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 170 V P VT+ P++T+ L HHNLLVCSV+ FYPG I+VRWFRN QEE AGVVST LI+NGDWT Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPGQIKVRWFRNDQEETAGVVSTPLIRNGDWT 186 Query: 171 FQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLG 230 FQ LVMLE P+ G+VYTC VEHPS+ SP+TVEWRA+SESAQSKMLSGVGGFVLGL+FLG Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSKMLSGVGGFVLGLIFLG 246 Query: 231 AGLFIYFRNQKG 242 GL I R+QKG Sbjct: 247 LGLIIRQRSQKG 258 >gi|239740920 PREDICTED: similar to major histocompatibility complex, class II, DQ beta 1 isoform 2 [Homo sapiens] Length = 261 Score = 275 bits (704), Expect = 2e-74 Identities = 143/252 (56%), Positives = 179/252 (71%), Gaps = 13/252 (5%) Query: 4 LKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLFYNQ 63 L++PGG +A +T+ L +LS+P+A D+ F++Q K C+F NGTERV+ + R YN+ Sbjct: 7 LRIPGGLRVATVTLMLAMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRGVTRYIYNR 66 Query: 64 EEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------CLPD-SFPLPCFLL-- 110 EE+ RFDSDVG YRAVT LG P AE Q ++L C + L L Sbjct: 67 EEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCRHNYQLELRTTLQRR 126 Query: 111 VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 170 V P VT+ P++T+ L HHNLLVCSV+ FYP I+VRWFRN QEE GVVST LI+NGDWT Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPLIRNGDWT 186 Query: 171 FQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLG 230 FQ LVMLE P+ G+VYTC VEHPS+ +P+ VEWRA+SESAQSKMLSG+GGFVLGL+FLG Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246 Query: 231 AGLFIYFRNQKG 242 GL I+ R+QKG Sbjct: 247 LGLIIHHRSQKG 258 >gi|239740918 PREDICTED: similar to major histocompatibility complex, class II, DQ beta 1 isoform 1 [Homo sapiens] Length = 281 Score = 275 bits (704), Expect = 2e-74 Identities = 143/252 (56%), Positives = 179/252 (71%), Gaps = 13/252 (5%) Query: 4 LKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLFYNQ 63 L++PGG +A +T+ L +LS+P+A D+ F++Q K C+F NGTERV+ + R YN+ Sbjct: 7 LRIPGGLRVATVTLMLAMLSTPVAEGRDSPEDFVYQFKGMCYFTNGTERVRGVTRYIYNR 66 Query: 64 EEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----------CLPD-SFPLPCFLL-- 110 EE+ RFDSDVG YRAVT LG P AE Q ++L C + L L Sbjct: 67 EEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTVCRHNYQLELRTTLQRR 126 Query: 111 VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 170 V P VT+ P++T+ L HHNLLVCSV+ FYP I+VRWFRN QEE GVVST LI+NGDWT Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPLIRNGDWT 186 Query: 171 FQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLG 230 FQ LVMLE P+ G+VYTC VEHPS+ +P+ VEWRA+SESAQSKMLSG+GGFVLGL+FLG Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESAQSKMLSGIGGFVLGLIFLG 246 Query: 231 AGLFIYFRNQKG 242 GL I+ R+QKG Sbjct: 247 LGLIIHHRSQKG 258 >gi|24797076 major histocompatibility complex, class II, DP beta 1 precursor [Homo sapiens] Length = 258 Score = 275 bits (703), Expect = 3e-74 Identities = 143/258 (55%), Positives = 178/258 (68%), Gaps = 15/258 (5%) Query: 1 MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60 M+ L++ ALT LMVL + + T +L+QG+ +C+ FNGT+R FLER Sbjct: 1 MMVLQVSAAPRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQR--FLERYI 58 Query: 61 YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL----CLPDSF---------PLPC 107 YN+EEF RFDSDVGE+RAVTELGRP AE Q D+L +PD P+ Sbjct: 59 YNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTL 118 Query: 108 FLLVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNG 167 V P V V P+K PLQHHNLLVC V+ FYPGSI+VRWF NGQEE AGVVST LI+NG Sbjct: 119 QRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNG 178 Query: 168 DWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLL 227 DWTFQ LVMLE P+ G+VYTCQVEH S+ SP+TVEW+A+S+SA+SK L+G GGFVLGL+ Sbjct: 179 DWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGLI 238 Query: 228 FLGAGLFIYFRNQKGHSG 245 G G+F++ R++K G Sbjct: 239 ICGVGIFMHRRSKKVQRG 256 >gi|169217452 PREDICTED: similar to HLA class II histocompatibility antigen, DRB1-4 beta chain, partial [Homo sapiens] Length = 223 Score = 260 bits (665), Expect = 7e-70 Identities = 134/179 (74%), Positives = 146/179 (81%), Gaps = 17/179 (9%) Query: 35 RFLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQG 94 RFL Q K++CHFFNGTERV+FL+R FY+QEE+VRFDSDVGEYRAVTELGRP AE Q Sbjct: 47 RFLEQVKHECHFFNGTERVRFLDRYFYHQEEYVRFDSDVGEYRAVTELGRPDAEYWNSQK 106 Query: 95 DLL----------C-----LPDSFPLPCFLLVHPEVTVYPAKTQPLQHHNLLVCSVSGFY 139 DLL C + +SF + V+PEVTVYPAKTQPLQHHNLLVCSV+GFY Sbjct: 107 DLLEQKRAAVDTYCRHNYGVGESFTVQ--RRVYPEVTVYPAKTQPLQHHNLLVCSVNGFY 164 Query: 140 PGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMS 198 PGSIEVRWFRNGQEEK GVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPS+ S Sbjct: 165 PGSIEVRWFRNGQEEKTGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSLTS 223 >gi|169168671 PREDICTED: similar to MHC class II antigen [Homo sapiens] Length = 241 Score = 258 bits (660), Expect = 3e-69 Identities = 124/140 (88%), Positives = 130/140 (92%) Query: 111 VHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWT 170 + P+ T+YPAKT+PL H N LVCSVSGFYPGSIEVRWF+NGQEEKA VVS GLIQNGDWT Sbjct: 99 LQPKGTMYPAKTEPLHHRNPLVCSVSGFYPGSIEVRWFQNGQEEKAAVVSIGLIQNGDWT 158 Query: 171 FQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLG 230 FQTLVMLETVPRSGEVYTCQVEHPSV SPLTVEW AR+ESAQSKMLSGVGGFVLGLLFLG Sbjct: 159 FQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWSARTESAQSKMLSGVGGFVLGLLFLG 218 Query: 231 AGLFIYFRNQKGHSGLQPTG 250 GLFIYFRNQKGHSGLQPTG Sbjct: 219 TGLFIYFRNQKGHSGLQPTG 238 >gi|4504403 major histocompatibility complex, class II, DO beta precursor [Homo sapiens] Length = 273 Score = 246 bits (629), Expect = 1e-65 Identities = 130/252 (51%), Positives = 167/252 (66%), Gaps = 13/252 (5%) Query: 12 MAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDS 71 + AL V L L S + D+ F+ Q K C+F NGTE+VQF+ R +N EE+VRFDS Sbjct: 9 VVALLVNLTRLDSSMTQGTDSPEDFVIQAKADCYFTNGTEKVQFVVRFIFNLEEYVRFDS 68 Query: 72 DVGEYRAVTELGRPVAEQKTKQGDLL----------CLPD---SFPLPCFLLVHPEVTVY 118 DVG + A+T+LG+P AEQ + DLL C + P V PEVTVY Sbjct: 69 DVGMFVALTKLGQPDAEQWNSRLDLLERSRQAVDGVCRHNYRLGAPFTVGRKVQPEVTVY 128 Query: 119 PAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLE 178 P +T L HNLL CSV+GFYPG I+++WF NGQEE+AGV+STG I+NGDWTFQT+VMLE Sbjct: 129 PERTPLLHQHNLLHCSVTGFYPGDIKIKWFLNGQEERAGVMSTGPIRNGDWTFQTVVMLE 188 Query: 179 TVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFR 238 P G VYTC V+H S++SP++VEWRA+SE + KMLSG+ F+LGL+FL G+ I R Sbjct: 189 MTPELGHVYTCLVDHSSLLSPVSVEWRAQSEYSWRKMLSGIAAFLLGLIFLLVGIVIQLR 248 Query: 239 NQKGHSGLQPTG 250 QKG+ Q +G Sbjct: 249 AQKGYVRTQMSG 260 >gi|169168589 PREDICTED: similar to MHC class II antigen [Homo sapiens] Length = 140 Score = 146 bits (369), Expect = 1e-35 Identities = 74/97 (76%), Positives = 80/97 (82%) Query: 1 MVCLKLPGGSCMAALTVTLMVLSSPLALAGDTQPRFLWQGKYKCHFFNGTERVQFLERLF 60 MVCLKLPGGSCMAALTVTL VLSSPLALAGDTQPRFL Q K +CHF NGTERV L R Sbjct: 1 MVCLKLPGGSCMAALTVTLTVLSSPLALAGDTQPRFLEQAKCECHFLNGTERVWNLIRYI 60 Query: 61 YNQEEFVRFDSDVGEYRAVTELGRPVAEQKTKQGDLL 97 YNQEE+ R++SD+GEY+AVTELGRP AE Q DLL Sbjct: 61 YNQEEYARYNSDLGEYQAVTELGRPDAEYWNSQKDLL 97 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.323 0.139 0.435 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,349,306 Number of Sequences: 37866 Number of extensions: 458721 Number of successful extensions: 1079 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 87 Number of HSP's successfully gapped in prelim test: 34 Number of HSP's that attempted gapping in prelim test: 898 Number of HSP's gapped (non-prelim): 166 length of query: 253 length of database: 18,247,518 effective HSP length: 100 effective length of query: 153 effective length of database: 14,460,918 effective search space: 2212520454 effective search space used: 2212520454 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.