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Search of human proteins with 11993943
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11993943 Tax1 binding protein 3 [Homo sapiens]
(124 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11993943 Tax1 binding protein 3 [Homo sapiens] 245 6e-66
gi|45827729 scribble isoform b [Homo sapiens] 61 2e-10
gi|45827731 scribble isoform a [Homo sapiens] 61 2e-10
gi|55770895 ERBB2 interacting protein isoform 7 [Homo sapiens] 59 1e-09
gi|8923909 ERBB2 interacting protein isoform 2 [Homo sapiens] 58 2e-09
gi|16904383 leucine rich repeat containing 7 [Homo sapiens] 57 5e-09
gi|218156340 chapsyn-110 isoform 3 [Homo sapiens] 56 6e-09
gi|218156338 chapsyn-110 isoform 1 [Homo sapiens] 56 6e-09
gi|91199538 chapsyn-110 isoform 2 [Homo sapiens] 56 6e-09
gi|119943106 synapse-associated protein 102 isoform a [Homo sapi... 54 3e-08
gi|157388993 synaptojanin 2 binding protein [Homo sapiens] 53 5e-08
gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens] 53 7e-08
gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens] 53 7e-08
gi|57529737 PDZ domain containing ring finger 3 [Homo sapiens] 52 9e-08
gi|4557529 post-synaptic density protein 95 isoform 1 [Homo sapi... 51 3e-07
gi|192447426 post-synaptic density protein 95 isoform 2 [Homo sa... 51 3e-07
gi|13376349 PDZ domain containing 7 [Homo sapiens] 50 4e-07
gi|194018553 solute carrier family 9 isoform 3 regulator 2 isofo... 50 6e-07
gi|71897229 solute carrier family 9 isoform 3 regulator 2 isofor... 50 6e-07
gi|119943108 synapse-associated protein 102 isoform b [Homo sapi... 49 1e-06
gi|140561024 CASK-interacting protein CIP98 isoform 1 [Homo sapi... 48 2e-06
gi|4759140 sodium/hydrogen exchanger regulatory factor 1 [Homo s... 47 5e-06
gi|41281808 harmonin isoform b3 [Homo sapiens] 46 6e-06
gi|71480164 harmonin isoform a [Homo sapiens] 46 6e-06
gi|148833504 interleukin 16 isoform 2 [Homo sapiens] 45 2e-05
gi|74272284 membrane associated guanylate kinase, WW and PDZ dom... 44 2e-05
gi|74272282 membrane associated guanylate kinase, WW and PDZ dom... 44 2e-05
gi|110346438 FERM and PDZ domain containing 2 isoform 1 [Homo sa... 44 2e-05
gi|110346436 FERM and PDZ domain containing 2 isoform 3 [Homo sa... 44 2e-05
gi|55749523 syntenin isoform 3 [Homo sapiens] 44 4e-05
>gi|11993943 Tax1 binding protein 3 [Homo sapiens]
Length = 124
Score = 245 bits (626), Expect = 6e-66
Identities = 124/124 (100%), Positives = 124/124 (100%)
Query: 1 MSYIPGQPVTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRV 60
MSYIPGQPVTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRV
Sbjct: 1 MSYIPGQPVTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRV 60
Query: 61 SEGGPAEIAGLQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQSLQKAVQQ 120
SEGGPAEIAGLQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQSLQKAVQQ
Sbjct: 61 SEGGPAEIAGLQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQSLQKAVQQ 120
Query: 121 SMLS 124
SMLS
Sbjct: 121 SMLS 124
>gi|45827729 scribble isoform b [Homo sapiens]
Length = 1630
Score = 61.2 bits (147), Expect = 2e-10
Identities = 35/81 (43%), Positives = 47/81 (58%), Gaps = 7/81 (8%)
Query: 29 LGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAG-LQIGDKIMQVNGWDMTM 87
LGFSI GG P + D GI+V+R++EGG A AG LQ+GD+++ +NG D+T
Sbjct: 872 LGFSIAGGKGSTPYR------AGDAGIFVSRIAEGGAAHRAGTLQVGDRVLSINGVDVTE 925
Query: 88 VTHDQARKRLTKRSEEVVRLL 108
HD A LT S + LL
Sbjct: 926 ARHDHAVSLLTAASPTIALLL 946
Score = 54.3 bits (129), Expect = 2e-08
Identities = 32/86 (37%), Positives = 52/86 (60%), Gaps = 7/86 (8%)
Query: 29 LGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNGWDMTMV 88
LG SI GG P+ D D+GI+++RVSE GPA AG+++GDK+++VNG +
Sbjct: 738 LGISIAGG----KGSTPYKGD--DEGIFISRVSEEGPAARAGVRVGDKLLEVNGVALQGA 791
Query: 89 THDQARKRLTKRSEEVVRLLVTRQSL 114
H +A + L + + V++ V R+ +
Sbjct: 792 EHHEAVEAL-RGAGTAVQMRVWRERM 816
Score = 49.3 bits (116), Expect = 8e-07
Identities = 32/83 (38%), Positives = 48/83 (57%), Gaps = 5/83 (6%)
Query: 29 LGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNGWDMTMV 88
LG SI GG D S +PF + G+++++V G A +GL++GD+I+ VNG D+
Sbjct: 1014 LGLSIVGGSDH--SSHPFGVQ--EPGVFISKVLPRGLAARSGLRVGDRILAVNGQDVRDA 1069
Query: 89 THDQARKRLTKRSEEVVRLLVTR 111
TH +A L + E + LLV R
Sbjct: 1070 THQEAVSALLRPCLE-LSLLVRR 1091
Score = 39.3 bits (90), Expect = 8e-04
Identities = 25/66 (37%), Positives = 41/66 (62%), Gaps = 4/66 (6%)
Query: 29 LGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAG-LQIGDKIMQVNGWDMTM 87
LG SI GG + + NP D TD+GI++++VS G A G L++G ++++VN +
Sbjct: 1111 LGISIRGGA-RGHAGNP--RDPTDEGIFISKVSPTGAAGRDGRLRVGLRLLEVNQQSLLG 1167
Query: 88 VTHDQA 93
+TH +A
Sbjct: 1168 LTHGEA 1173
>gi|45827731 scribble isoform a [Homo sapiens]
Length = 1655
Score = 61.2 bits (147), Expect = 2e-10
Identities = 35/81 (43%), Positives = 47/81 (58%), Gaps = 7/81 (8%)
Query: 29 LGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAG-LQIGDKIMQVNGWDMTM 87
LGFSI GG P + D GI+V+R++EGG A AG LQ+GD+++ +NG D+T
Sbjct: 872 LGFSIAGGKGSTPYR------AGDAGIFVSRIAEGGAAHRAGTLQVGDRVLSINGVDVTE 925
Query: 88 VTHDQARKRLTKRSEEVVRLL 108
HD A LT S + LL
Sbjct: 926 ARHDHAVSLLTAASPTIALLL 946
Score = 54.3 bits (129), Expect = 2e-08
Identities = 32/86 (37%), Positives = 52/86 (60%), Gaps = 7/86 (8%)
Query: 29 LGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNGWDMTMV 88
LG SI GG P+ D D+GI+++RVSE GPA AG+++GDK+++VNG +
Sbjct: 738 LGISIAGG----KGSTPYKGD--DEGIFISRVSEEGPAARAGVRVGDKLLEVNGVALQGA 791
Query: 89 THDQARKRLTKRSEEVVRLLVTRQSL 114
H +A + L + + V++ V R+ +
Sbjct: 792 EHHEAVEAL-RGAGTAVQMRVWRERM 816
Score = 49.3 bits (116), Expect = 8e-07
Identities = 32/83 (38%), Positives = 48/83 (57%), Gaps = 5/83 (6%)
Query: 29 LGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNGWDMTMV 88
LG SI GG D S +PF + G+++++V G A +GL++GD+I+ VNG D+
Sbjct: 1014 LGLSIVGGSDH--SSHPFGVQ--EPGVFISKVLPRGLAARSGLRVGDRILAVNGQDVRDA 1069
Query: 89 THDQARKRLTKRSEEVVRLLVTR 111
TH +A L + E + LLV R
Sbjct: 1070 THQEAVSALLRPCLE-LSLLVRR 1091
Score = 39.3 bits (90), Expect = 8e-04
Identities = 25/66 (37%), Positives = 41/66 (62%), Gaps = 4/66 (6%)
Query: 29 LGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAG-LQIGDKIMQVNGWDMTM 87
LG SI GG + + NP D TD+GI++++VS G A G L++G ++++VN +
Sbjct: 1111 LGISIRGGA-RGHAGNP--RDPTDEGIFISKVSPTGAAGRDGRLRVGLRLLEVNQQSLLG 1167
Query: 88 VTHDQA 93
+TH +A
Sbjct: 1168 LTHGEA 1173
>gi|55770895 ERBB2 interacting protein isoform 7 [Homo sapiens]
Length = 1302
Score = 58.9 bits (141), Expect = 1e-09
Identities = 40/99 (40%), Positives = 56/99 (56%), Gaps = 6/99 (6%)
Query: 14 QRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAGLQI 73
+++E ++R ++ LGFSI GG+ NPF D D GI+VTRV GPA LQ
Sbjct: 1207 KKLEKIRVRVEKDPELGFSISGGVGG--RGNPFRPD--DDGIFVTRVQPEGPASKL-LQP 1261
Query: 74 GDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQ 112
GDKI+Q NG+ + H QA L K + V L++ R+
Sbjct: 1262 GDKIIQANGYSFINIEHGQA-VSLLKTFQNTVELIIVRE 1299
>gi|8923909 ERBB2 interacting protein isoform 2 [Homo sapiens]
Length = 1371
Score = 57.8 bits (138), Expect = 2e-09
Identities = 38/84 (45%), Positives = 47/84 (55%), Gaps = 6/84 (7%)
Query: 29 LGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNGWDMTMV 88
LGFSI GG+ NPF D D GI+VTRV GPA LQ GDKI+Q NG+ +
Sbjct: 1291 LGFSISGGVGG--RGNPFRPD--DDGIFVTRVQPEGPASKL-LQPGDKIIQANGYSFINI 1345
Query: 89 THDQARKRLTKRSEEVVRLLVTRQ 112
H QA L K + V L++ R+
Sbjct: 1346 EHGQA-VSLLKTFQNTVELIIVRE 1368
>gi|16904383 leucine rich repeat containing 7 [Homo sapiens]
Length = 1537
Score = 56.6 bits (135), Expect = 5e-09
Identities = 40/92 (43%), Positives = 52/92 (56%), Gaps = 6/92 (6%)
Query: 21 LRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQV 80
+R +N LGFSI GGI NPF +DKGI+VTRV GPA LQ GDKI+Q
Sbjct: 1449 VRIEKNPGLGFSISGGISGQG--NPFKP--SDKGIFVTRVQPDGPASNL-LQPGDKILQA 1503
Query: 81 NGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQ 112
NG + H++A L K + V L++ R+
Sbjct: 1504 NGHSFVHMEHEKA-VLLLKSFQNTVDLVIQRE 1534
>gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]
Length = 749
Score = 56.2 bits (134), Expect = 6e-09
Identities = 36/104 (34%), Positives = 57/104 (54%), Gaps = 13/104 (12%)
Query: 7 QPVTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPA 66
+P+ V +++ K +G LGFSI GG+ D IYVT++ +GG A
Sbjct: 134 RPILETVVEIKLFKGPKG----LGFSIAGGVGNQHIPG-------DNSIYVTKIIDGGAA 182
Query: 67 EIAG-LQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLV 109
+ G LQ+GD+++ VN + + VTH++A + K + EVV L V
Sbjct: 183 QKDGRLQVGDRLLMVNNYSLEEVTHEEA-VAILKNTSEVVYLKV 225
Score = 51.2 bits (121), Expect = 2e-07
Identities = 35/85 (41%), Positives = 51/85 (60%), Gaps = 9/85 (10%)
Query: 29 LGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAG-LQIGDKIMQVNGWDMTM 87
LGFSI GG D NP D D GI++T++ GG A G L++ D I++VN D++
Sbjct: 57 LGFSIAGGTD-----NPHIGD--DPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSE 109
Query: 88 VTHDQARKRLTKRSEEVVRLLVTRQ 112
V+H +A + L K + +VRL V R+
Sbjct: 110 VSHSKAVEAL-KEAGSIVRLYVRRR 133
Score = 48.9 bits (115), Expect = 1e-06
Identities = 33/92 (35%), Positives = 50/92 (54%), Gaps = 18/92 (19%)
Query: 14 QRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAG-LQ 72
++V +HK G LGF+I GG D + GI+V+ + GGPA+++G LQ
Sbjct: 317 RKVVLHKGSTG----LGFNIVGGEDGE-------------GIFVSFILAGGPADLSGELQ 359
Query: 73 IGDKIMQVNGWDMTMVTHDQARKRLTKRSEEV 104
GD+I+ VNG D+ +H+QA L + V
Sbjct: 360 RGDQILSVNGIDLRGASHEQAAAALKGAGQTV 391
>gi|218156338 chapsyn-110 isoform 1 [Homo sapiens]
Length = 975
Score = 56.2 bits (134), Expect = 6e-09
Identities = 36/104 (34%), Positives = 57/104 (54%), Gaps = 13/104 (12%)
Query: 7 QPVTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPA 66
+P+ V +++ K +G LGFSI GG+ D IYVT++ +GG A
Sbjct: 290 RPILETVVEIKLFKGPKG----LGFSIAGGVGNQHIPG-------DNSIYVTKIIDGGAA 338
Query: 67 EIAG-LQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLV 109
+ G LQ+GD+++ VN + + VTH++A + K + EVV L V
Sbjct: 339 QKDGRLQVGDRLLMVNNYSLEEVTHEEA-VAILKNTSEVVYLKV 381
Score = 52.8 bits (125), Expect = 7e-08
Identities = 38/111 (34%), Positives = 60/111 (54%), Gaps = 13/111 (11%)
Query: 3 YIPGQPVTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSE 62
Y+ G + + + + + G LGFSI GG D NP D D GI++T++
Sbjct: 191 YVNGTEIEYEFEEITLERGNSG----LGFSIAGGTD-----NPHIGD--DPGIFITKIIP 239
Query: 63 GGPAEIAG-LQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQ 112
GG A G L++ D I++VN D++ V+H +A + L K + +VRL V R+
Sbjct: 240 GGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEAL-KEAGSIVRLYVRRR 289
Score = 48.9 bits (115), Expect = 1e-06
Identities = 33/92 (35%), Positives = 50/92 (54%), Gaps = 18/92 (19%)
Query: 14 QRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAG-LQ 72
++V +HK G LGF+I GG D + GI+V+ + GGPA+++G LQ
Sbjct: 525 RKVVLHKGSTG----LGFNIVGGEDGE-------------GIFVSFILAGGPADLSGELQ 567
Query: 73 IGDKIMQVNGWDMTMVTHDQARKRLTKRSEEV 104
GD+I+ VNG D+ +H+QA L + V
Sbjct: 568 RGDQILSVNGIDLRGASHEQAAAALKGAGQTV 599
>gi|91199538 chapsyn-110 isoform 2 [Homo sapiens]
Length = 870
Score = 56.2 bits (134), Expect = 6e-09
Identities = 36/104 (34%), Positives = 57/104 (54%), Gaps = 13/104 (12%)
Query: 7 QPVTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPA 66
+P+ V +++ K +G LGFSI GG+ D IYVT++ +GG A
Sbjct: 185 RPILETVVEIKLFKGPKG----LGFSIAGGVGNQHIPG-------DNSIYVTKIIDGGAA 233
Query: 67 EIAG-LQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLV 109
+ G LQ+GD+++ VN + + VTH++A + K + EVV L V
Sbjct: 234 QKDGRLQVGDRLLMVNNYSLEEVTHEEA-VAILKNTSEVVYLKV 276
Score = 52.8 bits (125), Expect = 7e-08
Identities = 38/111 (34%), Positives = 60/111 (54%), Gaps = 13/111 (11%)
Query: 3 YIPGQPVTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSE 62
Y+ G + + + + + G LGFSI GG D NP D D GI++T++
Sbjct: 86 YVNGTEIEYEFEEITLERGNSG----LGFSIAGGTD-----NPHIGD--DPGIFITKIIP 134
Query: 63 GGPAEIAG-LQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQ 112
GG A G L++ D I++VN D++ V+H +A + L K + +VRL V R+
Sbjct: 135 GGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAVEAL-KEAGSIVRLYVRRR 184
Score = 48.9 bits (115), Expect = 1e-06
Identities = 33/92 (35%), Positives = 50/92 (54%), Gaps = 18/92 (19%)
Query: 14 QRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAG-LQ 72
++V +HK G LGF+I GG D + GI+V+ + GGPA+++G LQ
Sbjct: 420 RKVVLHKGSTG----LGFNIVGGEDGE-------------GIFVSFILAGGPADLSGELQ 462
Query: 73 IGDKIMQVNGWDMTMVTHDQARKRLTKRSEEV 104
GD+I+ VNG D+ +H+QA L + V
Sbjct: 463 RGDQILSVNGIDLRGASHEQAAAALKGAGQTV 494
>gi|119943106 synapse-associated protein 102 isoform a [Homo
sapiens]
Length = 817
Score = 53.9 bits (128), Expect = 3e-08
Identities = 36/85 (42%), Positives = 52/85 (61%), Gaps = 9/85 (10%)
Query: 29 LGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAG-LQIGDKIMQVNGWDMTM 87
LGFSI GGID NP D D GI++T++ GG A + G L + D +++VN D++
Sbjct: 141 LGFSIAGGID-----NPHVPD--DPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVSE 193
Query: 88 VTHDQARKRLTKRSEEVVRLLVTRQ 112
V H +A + L K + VVRL+V R+
Sbjct: 194 VVHSRAVEAL-KEAGPVVRLVVRRR 217
Score = 51.6 bits (122), Expect = 2e-07
Identities = 37/106 (34%), Positives = 55/106 (51%), Gaps = 13/106 (12%)
Query: 7 QPVTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPA 66
QP + V + K +G LGFSI GGI D IY+T++ EGG A
Sbjct: 218 QPPPETIMEVNLLKGPKG----LGFSIAGGIGNQHIPG-------DNSIYITKIIEGGAA 266
Query: 67 EIAG-LQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTR 111
+ G LQIGD+++ VN ++ V H++A L K + ++V L V +
Sbjct: 267 QKDGRLQIGDRLLAVNNTNLQDVRHEEAVASL-KNTSDMVYLKVAK 311
Score = 48.9 bits (115), Expect = 1e-06
Identities = 31/92 (33%), Positives = 51/92 (55%), Gaps = 18/92 (19%)
Query: 14 QRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAG-LQ 72
+++ +HK G LGF+I GG D + GI+V+ + GGPA+++G L+
Sbjct: 385 RKIILHKGSTG----LGFNIVGGEDGE-------------GIFVSFILAGGPADLSGELR 427
Query: 73 IGDKIMQVNGWDMTMVTHDQARKRLTKRSEEV 104
GD+I+ VNG ++ TH+QA L + + V
Sbjct: 428 RGDRILSVNGVNLRNATHEQAAAALKRAGQSV 459
>gi|157388993 synaptojanin 2 binding protein [Homo sapiens]
Length = 145
Score = 53.1 bits (126), Expect = 5e-08
Identities = 31/66 (46%), Positives = 38/66 (57%), Gaps = 8/66 (12%)
Query: 29 LGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAG-LQIGDKIMQVNGWDMTM 87
LGF+I GG DQ N D GIYV+R+ E G A + G LQ GDKI+ VNG D+
Sbjct: 23 LGFNIVGGTDQQYVSN-------DSGIYVSRIKENGAAALDGRLQEGDKILSVNGQDLKN 75
Query: 88 VTHDQA 93
+ H A
Sbjct: 76 LLHQDA 81
>gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]
Length = 904
Score = 52.8 bits (125), Expect = 7e-08
Identities = 36/99 (36%), Positives = 52/99 (52%), Gaps = 12/99 (12%)
Query: 7 QPVTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPA 66
+PV+ + +++ K +G LGFSI GG+ D IYVT++ EGG A
Sbjct: 311 KPVSEKIMEIKLIKGPKG----LGFSIAGGVGNQHIPG-------DNSIYVTKIIEGGAA 359
Query: 67 EIAG-LQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEV 104
G LQIGDK++ VN + VTH++A L S+ V
Sbjct: 360 HKDGKLQIGDKLLAVNNVCLEEVTHEEAVTALKNTSDFV 398
Score = 50.4 bits (119), Expect = 3e-07
Identities = 38/112 (33%), Positives = 58/112 (51%), Gaps = 13/112 (11%)
Query: 2 SYIPGQPVTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVS 61
+Y+ G + + + + G LGFSI GG D NP D D I++T++
Sbjct: 211 TYVNGTDADYEYEEITLERGNSG----LGFSIAGGTD-----NPHIGD--DSSIFITKII 259
Query: 62 EGGPAEIAG-LQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQ 112
GG A G L++ D I++VN D+ VTH +A + L K + +VRL V R+
Sbjct: 260 TGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAVEAL-KEAGSIVRLYVKRR 310
Score = 46.2 bits (108), Expect = 6e-06
Identities = 30/97 (30%), Positives = 51/97 (52%), Gaps = 18/97 (18%)
Query: 9 VTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEI 68
+T ++V +H+ G LGF+I GG D + GI+++ + GGPA++
Sbjct: 460 ITREPRKVVLHRGSTG----LGFNIVGGEDGE-------------GIFISFILAGGPADL 502
Query: 69 AG-LQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEV 104
+G L+ GD+I+ VN D+ +H+QA L + V
Sbjct: 503 SGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAV 539
>gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]
Length = 926
Score = 52.8 bits (125), Expect = 7e-08
Identities = 36/99 (36%), Positives = 52/99 (52%), Gaps = 12/99 (12%)
Query: 7 QPVTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPA 66
+PV+ + +++ K +G LGFSI GG+ D IYVT++ EGG A
Sbjct: 311 KPVSEKIMEIKLIKGPKG----LGFSIAGGVGNQHIPG-------DNSIYVTKIIEGGAA 359
Query: 67 EIAG-LQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEV 104
G LQIGDK++ VN + VTH++A L S+ V
Sbjct: 360 HKDGKLQIGDKLLAVNNVCLEEVTHEEAVTALKNTSDFV 398
Score = 50.4 bits (119), Expect = 3e-07
Identities = 38/112 (33%), Positives = 58/112 (51%), Gaps = 13/112 (11%)
Query: 2 SYIPGQPVTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVS 61
+Y+ G + + + + G LGFSI GG D NP D D I++T++
Sbjct: 211 TYVNGTDADYEYEEITLERGNSG----LGFSIAGGTD-----NPHIGD--DSSIFITKII 259
Query: 62 EGGPAEIAG-LQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQ 112
GG A G L++ D I++VN D+ VTH +A + L K + +VRL V R+
Sbjct: 260 TGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAVEAL-KEAGSIVRLYVKRR 310
Score = 46.2 bits (108), Expect = 6e-06
Identities = 30/97 (30%), Positives = 51/97 (52%), Gaps = 18/97 (18%)
Query: 9 VTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEI 68
+T ++V +H+ G LGF+I GG D + GI+++ + GGPA++
Sbjct: 460 ITREPRKVVLHRGSTG----LGFNIVGGEDGE-------------GIFISFILAGGPADL 502
Query: 69 AG-LQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEV 104
+G L+ GD+I+ VN D+ +H+QA L + V
Sbjct: 503 SGELRKGDRIISVNSVDLRAASHEQAAAALKNAGQAV 539
>gi|57529737 PDZ domain containing ring finger 3 [Homo sapiens]
Length = 1066
Score = 52.4 bits (124), Expect = 9e-08
Identities = 32/84 (38%), Positives = 52/84 (61%), Gaps = 5/84 (5%)
Query: 29 LGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPA-EIAGLQIGDKIMQVNGWDMTM 87
LGF+I GG PS + + + +GI+V+++ + GPA + GLQI D+I++VNG D++
Sbjct: 259 LGFNIIGG---RPSVDNH-DGSSSEGIFVSKIVDSGPAAKEGGLQIHDRIIEVNGRDLSR 314
Query: 88 VTHDQARKRLTKRSEEVVRLLVTR 111
THDQA + E +V ++ R
Sbjct: 315 ATHDQAVEAFKTAKEPIVVQVLRR 338
>gi|4557529 post-synaptic density protein 95 isoform 1 [Homo
sapiens]
Length = 767
Score = 50.8 bits (120), Expect = 3e-07
Identities = 40/108 (37%), Positives = 54/108 (50%), Gaps = 13/108 (12%)
Query: 7 QPVTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPA 66
+P V +++ K +G LGFSI GG+ D IYVT++ EGG A
Sbjct: 195 KPPAEKVMEIKLIKGPKG----LGFSIAGGVGNQHIPG-------DNSIYVTKIIEGGAA 243
Query: 67 EIAG-LQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQS 113
G LQIGDKI+ VN + V H+ A L K + +VV L V + S
Sbjct: 244 HKDGRLQIGDKILAVNSVGLEDVMHEDAVAAL-KNTYDVVYLKVAKPS 290
Score = 48.5 bits (114), Expect = 1e-06
Identities = 35/85 (41%), Positives = 47/85 (55%), Gaps = 9/85 (10%)
Query: 29 LGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAG-LQIGDKIMQVNGWDMTM 87
LGFSI GG D NP D D I++T++ GG A G L++ D I+ VN D+
Sbjct: 118 LGFSIAGGTD-----NPHIGD--DPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVRE 170
Query: 88 VTHDQARKRLTKRSEEVVRLLVTRQ 112
VTH A + L K + +VRL V R+
Sbjct: 171 VTHSAAVEAL-KEAGSIVRLYVMRR 194
Score = 48.5 bits (114), Expect = 1e-06
Identities = 34/102 (33%), Positives = 54/102 (52%), Gaps = 23/102 (22%)
Query: 4 IPGQPVTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEG 63
IP +P +R+ IH+ G LGF+I GG D + GI+++ + G
Sbjct: 350 IPREP-----RRIVIHRGSTG----LGFNIVGGEDGE-------------GIFISFILAG 387
Query: 64 GPAEIAG-LQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEV 104
GPA+++G L+ GD+I+ VNG D+ +H+QA L + V
Sbjct: 388 GPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTV 429
>gi|192447426 post-synaptic density protein 95 isoform 2 [Homo
sapiens]
Length = 721
Score = 50.8 bits (120), Expect = 3e-07
Identities = 40/108 (37%), Positives = 54/108 (50%), Gaps = 13/108 (12%)
Query: 7 QPVTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPA 66
+P V +++ K +G LGFSI GG+ D IYVT++ EGG A
Sbjct: 149 KPPAEKVMEIKLIKGPKG----LGFSIAGGVGNQHIPG-------DNSIYVTKIIEGGAA 197
Query: 67 EIAG-LQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQS 113
G LQIGDKI+ VN + V H+ A L K + +VV L V + S
Sbjct: 198 HKDGRLQIGDKILAVNSVGLEDVMHEDAVAAL-KNTYDVVYLKVAKPS 244
Score = 48.5 bits (114), Expect = 1e-06
Identities = 35/85 (41%), Positives = 47/85 (55%), Gaps = 9/85 (10%)
Query: 29 LGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAG-LQIGDKIMQVNGWDMTM 87
LGFSI GG D NP D D I++T++ GG A G L++ D I+ VN D+
Sbjct: 72 LGFSIAGGTD-----NPHIGD--DPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVRE 124
Query: 88 VTHDQARKRLTKRSEEVVRLLVTRQ 112
VTH A + L K + +VRL V R+
Sbjct: 125 VTHSAAVEAL-KEAGSIVRLYVMRR 148
Score = 48.5 bits (114), Expect = 1e-06
Identities = 34/102 (33%), Positives = 54/102 (52%), Gaps = 23/102 (22%)
Query: 4 IPGQPVTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEG 63
IP +P +R+ IH+ G LGF+I GG D + GI+++ + G
Sbjct: 304 IPREP-----RRIVIHRGSTG----LGFNIVGGEDGE-------------GIFISFILAG 341
Query: 64 GPAEIAG-LQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEV 104
GPA+++G L+ GD+I+ VNG D+ +H+QA L + V
Sbjct: 342 GPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTV 383
>gi|13376349 PDZ domain containing 7 [Homo sapiens]
Length = 517
Score = 50.1 bits (118), Expect = 4e-07
Identities = 33/90 (36%), Positives = 44/90 (48%), Gaps = 15/90 (16%)
Query: 12 VVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAGL 71
++ V + K G LGFS+ GG + GI+V++V EG AE AGL
Sbjct: 83 IIHSVRVEKSPAGR---LGFSVRGGSEHG------------LGIFVSKVEEGSSAERAGL 127
Query: 72 QIGDKIMQVNGWDMTMVTHDQARKRLTKRS 101
+GDKI +VNG + T A K LT S
Sbjct: 128 CVGDKITEVNGLSLESTTMGSAVKVLTSSS 157
Score = 45.4 bits (106), Expect = 1e-05
Identities = 26/81 (32%), Positives = 43/81 (53%), Gaps = 13/81 (16%)
Query: 13 VQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAGLQ 72
V+R+ +H ++ LGF+I GG + GIYV++V GG AE G++
Sbjct: 207 VRRI-VHLYTTSDDFCLGFNIRGG------------KEFGLGIYVSKVDHGGLAEENGIK 253
Query: 73 IGDKIMQVNGWDMTMVTHDQA 93
+GD+++ NG ++H QA
Sbjct: 254 VGDQVLAANGVRFDDISHSQA 274
>gi|194018553 solute carrier family 9 isoform 3 regulator 2 isoform
a [Homo sapiens]
Length = 337
Score = 49.7 bits (117), Expect = 6e-07
Identities = 27/76 (35%), Positives = 45/76 (59%), Gaps = 1/76 (1%)
Query: 49 DKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLL 108
+K +G ++ RV G PAE A L+ GD++++VNG ++ TH Q +R+ K E RLL
Sbjct: 28 EKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVNGVNVEGETHHQVVQRI-KAVEGQTRLL 86
Query: 109 VTRQSLQKAVQQSMLS 124
V Q + +++ L+
Sbjct: 87 VVDQETDEELRRRQLT 102
Score = 39.3 bits (90), Expect = 8e-04
Identities = 21/61 (34%), Positives = 35/61 (57%), Gaps = 1/61 (1%)
Query: 49 DKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLL 108
DK+ G Y+ V G PA +GL+ D++++VNG ++ + H + + R +E RLL
Sbjct: 168 DKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASIKAREDE-ARLL 226
Query: 109 V 109
V
Sbjct: 227 V 227
>gi|71897229 solute carrier family 9 isoform 3 regulator 2 isoform b
[Homo sapiens]
Length = 326
Score = 49.7 bits (117), Expect = 6e-07
Identities = 27/76 (35%), Positives = 45/76 (59%), Gaps = 1/76 (1%)
Query: 49 DKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLL 108
+K +G ++ RV G PAE A L+ GD++++VNG ++ TH Q +R+ K E RLL
Sbjct: 28 EKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVNGVNVEGETHHQVVQRI-KAVEGQTRLL 86
Query: 109 VTRQSLQKAVQQSMLS 124
V Q + +++ L+
Sbjct: 87 VVDQETDEELRRRQLT 102
Score = 39.3 bits (90), Expect = 8e-04
Identities = 21/61 (34%), Positives = 35/61 (57%), Gaps = 1/61 (1%)
Query: 49 DKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLL 108
DK+ G Y+ V G PA +GL+ D++++VNG ++ + H + + R +E RLL
Sbjct: 168 DKSRPGQYIRSVDPGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASIKAREDE-ARLL 226
Query: 109 V 109
V
Sbjct: 227 V 227
>gi|119943108 synapse-associated protein 102 isoform b [Homo
sapiens]
Length = 512
Score = 48.9 bits (115), Expect = 1e-06
Identities = 31/92 (33%), Positives = 51/92 (55%), Gaps = 18/92 (19%)
Query: 14 QRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAG-LQ 72
+++ +HK G LGF+I GG D + GI+V+ + GGPA+++G L+
Sbjct: 48 RKIILHKGSTG----LGFNIVGGEDGE-------------GIFVSFILAGGPADLSGELR 90
Query: 73 IGDKIMQVNGWDMTMVTHDQARKRLTKRSEEV 104
GD+I+ VNG ++ TH+QA L + + V
Sbjct: 91 RGDRILSVNGVNLRNATHEQAAAALKRAGQSV 122
>gi|140561024 CASK-interacting protein CIP98 isoform 1 [Homo
sapiens]
Length = 907
Score = 48.1 bits (113), Expect = 2e-06
Identities = 29/82 (35%), Positives = 43/82 (52%), Gaps = 13/82 (15%)
Query: 24 GENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNGW 83
G+ LG +I GG + GIY+T V G AE +GL++GD+I++VNG
Sbjct: 285 GDGRSLGLTIRGGAEYG------------LGIYITGVDPGSEAEGSGLKVGDQILEVNGR 332
Query: 84 DMTMVTHDQARKRLTKRSEEVV 105
+ HD+A RL K S ++
Sbjct: 333 SFLNILHDEA-VRLLKSSRHLI 353
Score = 47.0 bits (110), Expect = 4e-06
Identities = 37/101 (36%), Positives = 54/101 (53%), Gaps = 14/101 (13%)
Query: 6 GQPVTAVVQRVEIHKLRQGE-NLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGG 64
G P +A V + LR+ + + LGFSI GG + GIYV+ V G
Sbjct: 128 GGPDSAGPGEVRLVSLRRAKAHEGLGFSIRGGSEHGV------------GIYVSLVEPGS 175
Query: 65 PAEIAGLQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVV 105
AE GL++GD+I++VN + VTH +A K L K S+++V
Sbjct: 176 LAEKEGLRVGDQILRVNDKSLARVTHAEAVKAL-KGSKKLV 215
>gi|4759140 sodium/hydrogen exchanger regulatory factor 1 [Homo
sapiens]
Length = 358
Score = 46.6 bits (109), Expect = 5e-06
Identities = 29/72 (40%), Positives = 41/72 (56%), Gaps = 5/72 (6%)
Query: 49 DKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLL 108
+K G Y+ V G PAE AGL GD++++VNG ++ TH Q R+ + + VRLL
Sbjct: 31 EKGKLGQYIRLVEPGSPAEKAGLLAGDRLVEVNGENVEKETHQQVVSRI-RAALNAVRLL 89
Query: 109 V----TRQSLQK 116
V T + LQK
Sbjct: 90 VVDPETDEQLQK 101
Score = 37.7 bits (86), Expect = 0.002
Identities = 20/65 (30%), Positives = 33/65 (50%)
Query: 49 DKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLL 108
DK+ G ++ V PAE +GL+ D+I++VNG M H + +E L+
Sbjct: 171 DKSKPGQFIRSVDPDSPAEASGLRAQDRIVEVNGVCMEGKQHGDVVSAIRAGGDETKLLV 230
Query: 109 VTRQS 113
V R++
Sbjct: 231 VDRET 235
>gi|41281808 harmonin isoform b3 [Homo sapiens]
Length = 899
Score = 46.2 bits (108), Expect = 6e-06
Identities = 25/91 (27%), Positives = 50/91 (54%), Gaps = 23/91 (25%)
Query: 29 LGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNGWDMTMV 88
LG S+ GG++ G++++ + +GG A+ GLQ+GD+I+++NG+ ++
Sbjct: 98 LGLSVRGGLE------------FGCGLFISHLIKGGQADSVGLQVGDEIVRINGYSISSC 145
Query: 89 THDQARKRLTKRSEEVVRLLVTRQSLQKAVQ 119
TH EEV+ L+ T++++ V+
Sbjct: 146 TH-----------EEVINLIRTKKTVSIKVR 165
Score = 40.8 bits (94), Expect = 3e-04
Identities = 22/68 (32%), Positives = 36/68 (52%), Gaps = 8/68 (11%)
Query: 26 NLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNGWDM 85
+L+ +G I P Q P GI+++ V G + GL+IGD+I++VNG D
Sbjct: 215 SLVGSRGLGCSISSGPIQKP--------GIFISHVKPGSLSAEVGLEIGDQIVEVNGVDF 266
Query: 86 TMVTHDQA 93
+ + H +A
Sbjct: 267 SNLDHKEA 274
Score = 27.7 bits (60), Expect = 2.4
Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 12/84 (14%)
Query: 17 EIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEI-AGLQIGD 75
++ LR + L ++ GG+D +P + + V+ V E G AE G+ GD
Sbjct: 752 DVRLLRIKKEGSLDLALEGGVD-----SPIGK------VVVSAVYERGAAERHGGIVKGD 800
Query: 76 KIMQVNGWDMTMVTHDQARKRLTK 99
+IM +NG +T T +A L K
Sbjct: 801 EIMAINGKIVTDYTLAEAEAALQK 824
>gi|71480164 harmonin isoform a [Homo sapiens]
Length = 552
Score = 46.2 bits (108), Expect = 6e-06
Identities = 25/91 (27%), Positives = 50/91 (54%), Gaps = 23/91 (25%)
Query: 29 LGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNGWDMTMV 88
LG S+ GG++ G++++ + +GG A+ GLQ+GD+I+++NG+ ++
Sbjct: 98 LGLSVRGGLE------------FGCGLFISHLIKGGQADSVGLQVGDEIVRINGYSISSC 145
Query: 89 THDQARKRLTKRSEEVVRLLVTRQSLQKAVQ 119
TH EEV+ L+ T++++ V+
Sbjct: 146 TH-----------EEVINLIRTKKTVSIKVR 165
Score = 40.8 bits (94), Expect = 3e-04
Identities = 22/68 (32%), Positives = 36/68 (52%), Gaps = 8/68 (11%)
Query: 26 NLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAGLQIGDKIMQVNGWDM 85
+L+ +G I P Q P GI+++ V G + GL+IGD+I++VNG D
Sbjct: 215 SLVGSRGLGCSISSGPIQKP--------GIFISHVKPGSLSAEVGLEIGDQIVEVNGVDF 266
Query: 86 TMVTHDQA 93
+ + H +A
Sbjct: 267 SNLDHKEA 274
Score = 27.7 bits (60), Expect = 2.4
Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 12/84 (14%)
Query: 17 EIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEI-AGLQIGD 75
++ LR + L ++ GG+D +P + + V+ V E G AE G+ GD
Sbjct: 452 DVRLLRIKKEGSLDLALEGGVD-----SPIGK------VVVSAVYERGAAERHGGIVKGD 500
Query: 76 KIMQVNGWDMTMVTHDQARKRLTK 99
+IM +NG +T T +A L K
Sbjct: 501 EIMAINGKIVTDYTLAEAEAALQK 524
>gi|148833504 interleukin 16 isoform 2 [Homo sapiens]
Length = 1332
Score = 44.7 bits (104), Expect = 2e-05
Identities = 32/90 (35%), Positives = 47/90 (52%), Gaps = 10/90 (11%)
Query: 21 LRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAG-LQIGDKIMQ 79
L +G+ LGFSI GG +D P GIYV + GG A G LQ GD+I++
Sbjct: 219 LMKGQAKGLGFSIVGG--KDSIYGPI-------GIYVKTIFAGGAAAADGRLQEGDEILE 269
Query: 80 VNGWDMTMVTHDQARKRLTKRSEEVVRLLV 109
+NG M +TH A ++ + + ++ L V
Sbjct: 270 LNGESMAGLTHQDALQKFKQAKKGLLTLTV 299
Score = 38.5 bits (88), Expect = 0.001
Identities = 30/104 (28%), Positives = 49/104 (47%), Gaps = 12/104 (11%)
Query: 16 VEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAG-LQIG 74
+ + L + E LGFS+ GG D + +K I V RV G A G +Q G
Sbjct: 1111 IHVTILHKEEGAGLGFSLAGGADLE-----------NKVITVHRVFPNGLASQEGTIQKG 1159
Query: 75 DKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQSLQKAV 118
++++ +NG + TH A L + E ++VTR+ +A+
Sbjct: 1160 NEVLSINGKSLKGTTHHDALAILRQAREPRQAVIVTRKLTPEAM 1203
Score = 34.3 bits (77), Expect = 0.025
Identities = 30/106 (28%), Positives = 51/106 (48%), Gaps = 14/106 (13%)
Query: 11 AVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAG 70
A V V + K+ G LGFS+ GG DK + + R+ +G +E +
Sbjct: 1230 ATVCTVTLEKMSAG----LGFSLEGGKGSLHG---------DKPLTINRIFKGAASEQSE 1276
Query: 71 -LQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQSLQ 115
+Q GD+I+Q+ G M +T +A + + V +++ R+SLQ
Sbjct: 1277 TVQPGDEILQLGGTAMQGLTRFEAWNIIKALPDGPVTIVIRRKSLQ 1322
>gi|74272284 membrane associated guanylate kinase, WW and PDZ domain
containing 1 isoform c [Homo sapiens]
Length = 1462
Score = 44.3 bits (103), Expect = 2e-05
Identities = 27/83 (32%), Positives = 45/83 (54%), Gaps = 2/83 (2%)
Query: 9 VTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEI 68
V+ VVQ ++ ++R+GEN GF I + + + F + R+ EG PA+
Sbjct: 962 VSTVVQPYDV-EIRRGENEGFGFVIVSSVSRPEAGTTFGNACVAMPHKIGRIIEGSPADR 1020
Query: 69 AG-LQIGDKIMQVNGWDMTMVTH 90
G L++GD+I+ VNG +T +H
Sbjct: 1021 CGKLKVGDRILAVNGCSITNKSH 1043
Score = 40.4 bits (93), Expect = 4e-04
Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 14/83 (16%)
Query: 30 GFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAG-LQIGDKIMQVNGWDMTMV 88
GFS+ GG + + +YV R++E GPAE G ++IGD+I+++NG +
Sbjct: 1134 GFSLRGGREYNMD------------LYVLRLAEDGPAERCGKMRIGDEILEINGETTKNM 1181
Query: 89 THDQARKRLTKRSEEVVRLLVTR 111
H +A + L K VRL + R
Sbjct: 1182 KHSRAIE-LIKNGGRRVRLFLKR 1203
Score = 25.8 bits (55), Expect = 8.9
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 5/48 (10%)
Query: 70 GLQIGDKIMQVNGWDMTMVTHDQARKRLT---KRSEEVVRLLVTRQSL 114
GL+ GD I++VN ++ +TH+Q L K SE V LLV R L
Sbjct: 679 GLKEGDLIVEVNKKNVQALTHNQVVDMLVECPKGSE--VTLLVQRGGL 724
>gi|74272282 membrane associated guanylate kinase, WW and PDZ domain
containing 1 isoform a [Homo sapiens]
Length = 1287
Score = 44.3 bits (103), Expect = 2e-05
Identities = 27/83 (32%), Positives = 45/83 (54%), Gaps = 2/83 (2%)
Query: 9 VTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEI 68
V+ VVQ ++ ++R+GEN GF I + + + F + R+ EG PA+
Sbjct: 990 VSTVVQPYDV-EIRRGENEGFGFVIVSSVSRPEAGTTFGNACVAMPHKIGRIIEGSPADR 1048
Query: 69 AG-LQIGDKIMQVNGWDMTMVTH 90
G L++GD+I+ VNG +T +H
Sbjct: 1049 CGKLKVGDRILAVNGCSITNKSH 1071
Score = 40.4 bits (93), Expect = 4e-04
Identities = 28/83 (33%), Positives = 44/83 (53%), Gaps = 14/83 (16%)
Query: 30 GFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAG-LQIGDKIMQVNGWDMTMV 88
GFS+ GG + + +YV R++E GPAE G ++IGD+I+++NG +
Sbjct: 1162 GFSLRGGREYNMD------------LYVLRLAEDGPAERCGKMRIGDEILEINGETTKNM 1209
Query: 89 THDQARKRLTKRSEEVVRLLVTR 111
H +A + L K VRL + R
Sbjct: 1210 KHSRAIE-LIKNGGRRVRLFLKR 1231
Score = 25.8 bits (55), Expect = 8.9
Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 5/48 (10%)
Query: 70 GLQIGDKIMQVNGWDMTMVTHDQARKRLT---KRSEEVVRLLVTRQSL 114
GL+ GD I++VN ++ +TH+Q L K SE V LLV R L
Sbjct: 679 GLKEGDLIVEVNKKNVQALTHNQVVDMLVECPKGSE--VTLLVQRGGL 724
>gi|110346438 FERM and PDZ domain containing 2 isoform 1 [Homo
sapiens]
Length = 1287
Score = 44.3 bits (103), Expect = 2e-05
Identities = 35/97 (36%), Positives = 56/97 (57%), Gaps = 12/97 (12%)
Query: 25 ENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAGLQI-GDKIMQVNGW 83
E+ LGFS+ GGI+ + P+ GIYV + GGPA G + GD+++QV+G
Sbjct: 934 EDGTLGFSVTGGIN---TSVPYG------GIYVKSIVPGGPAAKEGQILQGDRLLQVDGV 984
Query: 84 DMTMVTHDQARKRLTKRSEEVVRLLVTRQSLQKAVQQ 120
+ +TH QA + LT +V RL++ R+ + ++ QQ
Sbjct: 985 ILCGLTHKQAVQCLTGPG-QVARLVLERR-VPRSTQQ 1019
Score = 29.6 bits (65), Expect = 0.62
Identities = 17/63 (26%), Positives = 37/63 (58%), Gaps = 2/63 (3%)
Query: 50 KTDKGIYVTRVSEGGPAEIA-GLQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLL 108
+ D GI+++ + GGPAE A ++ G +I+ +N + T + A R+ + S + + L+
Sbjct: 776 QADPGIFISSIIPGGPAEKAKTIKPGGQILALNHISLEGFTFNMA-VRMIQNSPDNIELI 834
Query: 109 VTR 111
+++
Sbjct: 835 ISQ 837
>gi|110346436 FERM and PDZ domain containing 2 isoform 3 [Homo
sapiens]
Length = 1309
Score = 44.3 bits (103), Expect = 2e-05
Identities = 35/97 (36%), Positives = 56/97 (57%), Gaps = 12/97 (12%)
Query: 25 ENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAGLQI-GDKIMQVNGW 83
E+ LGFS+ GGI+ + P+ GIYV + GGPA G + GD+++QV+G
Sbjct: 956 EDGTLGFSVTGGIN---TSVPYG------GIYVKSIVPGGPAAKEGQILQGDRLLQVDGV 1006
Query: 84 DMTMVTHDQARKRLTKRSEEVVRLLVTRQSLQKAVQQ 120
+ +TH QA + LT +V RL++ R+ + ++ QQ
Sbjct: 1007 ILCGLTHKQAVQCLTGPG-QVARLVLERR-VPRSTQQ 1041
Score = 29.6 bits (65), Expect = 0.62
Identities = 17/63 (26%), Positives = 37/63 (58%), Gaps = 2/63 (3%)
Query: 50 KTDKGIYVTRVSEGGPAEIA-GLQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLL 108
+ D GI+++ + GGPAE A ++ G +I+ +N + T + A R+ + S + + L+
Sbjct: 798 QADPGIFISSIIPGGPAEKAKTIKPGGQILALNHISLEGFTFNMA-VRMIQNSPDNIELI 856
Query: 109 VTR 111
+++
Sbjct: 857 ISQ 859
>gi|55749523 syntenin isoform 3 [Homo sapiens]
Length = 297
Score = 43.5 bits (101), Expect = 4e-05
Identities = 19/67 (28%), Positives = 37/67 (55%)
Query: 52 DKGIYVTRVSEGGPAEIAGLQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTR 111
D GI+V V PA + GL+ GD+++Q+NG + + D+A K L + E + + +
Sbjct: 132 DNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRD 191
Query: 112 QSLQKAV 118
+ ++ +
Sbjct: 192 RPFERTI 198
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.370
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,167,845
Number of Sequences: 37866
Number of extensions: 165947
Number of successful extensions: 714
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 142
Number of HSP's successfully gapped in prelim test: 42
Number of HSP's that attempted gapping in prelim test: 388
Number of HSP's gapped (non-prelim): 296
length of query: 124
length of database: 18,247,518
effective HSP length: 89
effective length of query: 35
effective length of database: 14,877,444
effective search space: 520710540
effective search space used: 520710540
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.