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Search of human proteins with 239755296
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239755296 PREDICTED: similar to hCG1644292 [Homo sapiens]
(671 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239755296 PREDICTED: similar to hCG1644292 [Homo sapiens] 1373 0.0
gi|239749791 PREDICTED: similar to hCG1644292 [Homo sapiens] 1369 0.0
gi|126091152 cubilin [Homo sapiens] 459 e-129
gi|222537750 ankyrin repeat domain 30B [Homo sapiens] 239 6e-63
gi|115495445 ankyrin repeat domain 30A [Homo sapiens] 196 4e-50
gi|239757619 PREDICTED: similar to hCG1644292 [Homo sapiens] 185 1e-46
gi|239752110 PREDICTED: hypothetical protein XP_002348113 [Homo ... 185 1e-46
gi|239743843 PREDICTED: hypothetical protein XP_002342968 [Homo ... 169 6e-42
gi|239743812 PREDICTED: similar to hCG1644292 [Homo sapiens] 169 6e-42
gi|239758143 PREDICTED: similar to hCG1644292 [Homo sapiens] 164 3e-40
gi|22547221 tolloid-like 1 [Homo sapiens] 101 2e-21
gi|6912724 tolloid-like 2 [Homo sapiens] 97 6e-20
gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Hom... 94 3e-19
gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Hom... 86 9e-17
gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Hom... 86 9e-17
gi|7019483 procollagen C-endopeptidase enhancer 2 [Homo sapiens] 83 9e-16
gi|72384339 CUB domain containing protein 2 [Homo sapiens] 78 2e-14
gi|157653329 procollagen C-endopeptidase enhancer [Homo sapiens] 73 7e-13
gi|30520377 CUB and zona pellucida-like domains 1 [Homo sapiens] 72 1e-12
gi|239756223 PREDICTED: ankyrin repeat domain-containing protein... 68 3e-11
gi|169209369 PREDICTED: similar to Putative ankyrin repeat domai... 68 3e-11
gi|239745040 PREDICTED: ankyrin repeat domain-containing protein... 68 3e-11
gi|20373181 neuropilin- and tolloid-like protein 1 isoform 3 pre... 67 4e-11
gi|23510396 neuropilin- and tolloid-like protein 1 isoform 2 pre... 67 4e-11
gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens] 62 1e-09
gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens] 62 1e-09
gi|148539844 deleted in malignant brain tumors 1 isoform c precu... 62 1e-09
gi|148539842 deleted in malignant brain tumors 1 isoform b precu... 62 1e-09
gi|148539840 deleted in malignant brain tumors 1 isoform a precu... 62 1e-09
gi|54792129 discoidin, CUB and LCCL domain containing 2 [Homo sa... 62 2e-09
>gi|239755296 PREDICTED: similar to hCG1644292 [Homo sapiens]
Length = 671
Score = 1373 bits (3554), Expect = 0.0
Identities = 671/671 (100%), Positives = 671/671 (100%)
Query: 1 MYLRFRSDNSPNHMGFKGLSRHYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYC 60
MYLRFRSDNSPNHMGFKGLSRHYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYC
Sbjct: 1 MYLRFRSDNSPNHMGFKGLSRHYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYC 60
Query: 61 ANTIPDSTDTSSNTAVVRVWWGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLT 120
ANTIPDSTDTSSNTAVVRVWWGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLT
Sbjct: 61 ANTIPDSTDTSSNTAVVRVWWGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLT 120
Query: 121 FSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSR 180
FSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSR
Sbjct: 121 FSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSR 180
Query: 181 PYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNP 240
PYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNP
Sbjct: 181 PYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNP 240
Query: 241 NQGNSSIYIHFEDFYLESHQDCQFDVLEFRVVASEHWKVPFSLISRLSGWSECSLERNLF 300
NQGNSSIYIHFEDFYLESHQDCQFDVLEFRVVASEHWKVPFSLISRLSGWSECSLERNLF
Sbjct: 241 NQGNSSIYIHFEDFYLESHQDCQFDVLEFRVVASEHWKVPFSLISRLSGWSECSLERNLF 300
Query: 301 ADGTGLRELLKGGGHGRRLQVHRVLLEHWDDLLHLQSHSFQALGVVLLQDVQLRLGQVWR 360
ADGTGLRELLKGGGHGRRLQVHRVLLEHWDDLLHLQSHSFQALGVVLLQDVQLRLGQVWR
Sbjct: 301 ADGTGLRELLKGGGHGRRLQVHRVLLEHWDDLLHLQSHSFQALGVVLLQDVQLRLGQVWR 360
Query: 361 HMASLVQGIHQAPRRSSMVMTELWLVQARMWSLPLQETECRAVWPLSAAQGSVPFSSSYR 420
HMASLVQGIHQAPRRSSMVMTELWLVQARMWSLPLQETECRAVWPLSAAQGSVPFSSSYR
Sbjct: 361 HMASLVQGIHQAPRRSSMVMTELWLVQARMWSLPLQETECRAVWPLSAAQGSVPFSSSYR 420
Query: 421 TFSTSLALVALALSPSFSSELHLFARATTPGAALRHTATSRVVVQWGLGPGGLLAREAHA 480
TFSTSLALVALALSPSFSSELHLFARATTPGAALRHTATSRVVVQWGLGPGGLLAREAHA
Sbjct: 421 TFSTSLALVALALSPSFSSELHLFARATTPGAALRHTATSRVVVQWGLGPGGLLAREAHA 480
Query: 481 AAPVQTRSQRRRRGPSLARLADSALNTNPRPYPIFLHCLPALSQSHATEQPEGTSEGTPD 540
AAPVQTRSQRRRRGPSLARLADSALNTNPRPYPIFLHCLPALSQSHATEQPEGTSEGTPD
Sbjct: 481 AAPVQTRSQRRRRGPSLARLADSALNTNPRPYPIFLHCLPALSQSHATEQPEGTSEGTPD 540
Query: 541 EAAPLAERTPDMAESLVEKPPDEAAPLVEGTADKIQCLGKATSGKFEQSAEETPKKIMRT 600
EAAPLAERTPDMAESLVEKPPDEAAPLVEGTADKIQCLGKATSGKFEQSAEETPKKIMRT
Sbjct: 541 EAAPLAERTPDMAESLVEKPPDEAAPLVEGTADKIQCLGKATSGKFEQSAEETPKKIMRT 600
Query: 601 AKETSKKFAWPAKERPRKITWEEKETSVKTECVAGVIPNKTEVLEKGTSEMLTCPTKETS 660
AKETSKKFAWPAKERPRKITWEEKETSVKTECVAGVIPNKTEVLEKGTSEMLTCPTKETS
Sbjct: 601 AKETSKKFAWPAKERPRKITWEEKETSVKTECVAGVIPNKTEVLEKGTSEMLTCPTKETS 660
Query: 661 TKASTNGKMLE 671
TKASTNGKMLE
Sbjct: 661 TKASTNGKMLE 671
>gi|239749791 PREDICTED: similar to hCG1644292 [Homo sapiens]
Length = 671
Score = 1369 bits (3544), Expect = 0.0
Identities = 669/671 (99%), Positives = 670/671 (99%)
Query: 1 MYLRFRSDNSPNHMGFKGLSRHYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYC 60
MYLRFRSDNSPNHMGFKGLSRHYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYC
Sbjct: 1 MYLRFRSDNSPNHMGFKGLSRHYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYC 60
Query: 61 ANTIPDSTDTSSNTAVVRVWWGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLT 120
ANTIPDSTDTSSNTAVVRVWWGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLT
Sbjct: 61 ANTIPDSTDTSSNTAVVRVWWGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLT 120
Query: 121 FSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSR 180
FSNLRLA HLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSR
Sbjct: 121 FSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSR 180
Query: 181 PYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNP 240
PYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNP
Sbjct: 181 PYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNP 240
Query: 241 NQGNSSIYIHFEDFYLESHQDCQFDVLEFRVVASEHWKVPFSLISRLSGWSECSLERNLF 300
NQGNSSIYIHFEDFYLESHQDCQFDVLEFRVVASEHWKVPFSLISRLSGWSECSLERNLF
Sbjct: 241 NQGNSSIYIHFEDFYLESHQDCQFDVLEFRVVASEHWKVPFSLISRLSGWSECSLERNLF 300
Query: 301 ADGTGLRELLKGGGHGRRLQVHRVLLEHWDDLLHLQSHSFQALGVVLLQDVQLRLGQVWR 360
ADGTGLRELLKGGGHGRRLQVHRVLLEHWDDLLHLQSHSFQALGVVLLQDVQLRLGQVWR
Sbjct: 301 ADGTGLRELLKGGGHGRRLQVHRVLLEHWDDLLHLQSHSFQALGVVLLQDVQLRLGQVWR 360
Query: 361 HMASLVQGIHQAPRRSSMVMTELWLVQARMWSLPLQETECRAVWPLSAAQGSVPFSSSYR 420
HMASLVQGIHQAPRRSSMVMTELWLVQARMWSLPLQETECRAVWPLSAAQGSVPFSSSYR
Sbjct: 361 HMASLVQGIHQAPRRSSMVMTELWLVQARMWSLPLQETECRAVWPLSAAQGSVPFSSSYR 420
Query: 421 TFSTSLALVALALSPSFSSELHLFARATTPGAALRHTATSRVVVQWGLGPGGLLAREAHA 480
TFSTSLALVALALSPSFSSELHLFARATTPGAALRHTATSRVVVQWGLGPGGLLAREAHA
Sbjct: 421 TFSTSLALVALALSPSFSSELHLFARATTPGAALRHTATSRVVVQWGLGPGGLLAREAHA 480
Query: 481 AAPVQTRSQRRRRGPSLARLADSALNTNPRPYPIFLHCLPALSQSHATEQPEGTSEGTPD 540
AAPVQTRSQRRRRGPSLARLADSALNTNPRPYPIFLHCLPALSQSHATEQPEGTSEGTPD
Sbjct: 481 AAPVQTRSQRRRRGPSLARLADSALNTNPRPYPIFLHCLPALSQSHATEQPEGTSEGTPD 540
Query: 541 EAAPLAERTPDMAESLVEKPPDEAAPLVEGTADKIQCLGKATSGKFEQSAEETPKKIMRT 600
EAAPLAERTPDMAESLVEKPPDEAAPLVEGTADKIQCLGKATSGKFEQSAEETPKKIMRT
Sbjct: 541 EAAPLAERTPDMAESLVEKPPDEAAPLVEGTADKIQCLGKATSGKFEQSAEETPKKIMRT 600
Query: 601 AKETSKKFAWPAKERPRKITWEEKETSVKTECVAGVIPNKTEVLEKGTSEMLTCPTKETS 660
AKETS+KFAWPAKERPRKITWEEKETSVKTECVAGVIPNKTEVLEKGTSEMLTCPTKETS
Sbjct: 601 AKETSEKFAWPAKERPRKITWEEKETSVKTECVAGVIPNKTEVLEKGTSEMLTCPTKETS 660
Query: 661 TKASTNGKMLE 671
TKASTNGKMLE
Sbjct: 661 TKASTNGKMLE 671
>gi|126091152 cubilin [Homo sapiens]
Length = 3623
Score = 459 bits (1182), Expect = e-129
Identities = 242/333 (72%), Positives = 249/333 (74%), Gaps = 69/333 (20%)
Query: 1 MYLRFRSDNSPNHMGFK----------------------------------------GLS 20
MYLRFRSDNSP H+GFK GLS
Sbjct: 2312 MYLRFRSDNSPTHVGFKAKYSIAQCGGRVPGQSGVVESIGHPTLPYRDNLFCEWHLQGLS 2371
Query: 21 RHYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYCANTIPDSTDTSSNTAVVR-V 79
HYLT SFEDFNLQNSSGCEKDFVEIWD HTSGNILGRYC NTIPDS DTSSNTAVVR V
Sbjct: 2372 GHYLTISFEDFNLQNSSGCEKDFVEIWDNHTSGNILGRYCGNTIPDSIDTSSNTAVVRFV 2431
Query: 80 WWGS---------------------QGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQIT 118
GS QGS GT TSPNYPN NPHGRI EWRITAPEGR+IT
Sbjct: 2432 TDGSVTASGFRLRFESSMEECGGDLQGSIGTFTSPNYPNPNPHGRICEWRITAPEGRRIT 2491
Query: 119 LTFSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDG 178
L F+NLRLATH SCN+EHVIVFNGIRSNSPQLEKLCSSVNVS+EIKSSGNTMKVIFFTDG
Sbjct: 2492 LMFNNLRLATHPSCNNEHVIVFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDG 2551
Query: 179 SRPYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLS 238
SRPYGGFTAS+TSSEDA +CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLS
Sbjct: 2552 SRPYGGFTASYTSSEDA-------VCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLS 2604
Query: 239 NPNQGNSSIYIHFEDFYLESHQDCQFDVLEFRV 271
NPNQGNSSI IHFEDFYLESHQDCQFDVLEFRV
Sbjct: 2605 NPNQGNSSISIHFEDFYLESHQDCQFDVLEFRV 2637
Score = 90.9 bits (224), Expect = 3e-18
Identities = 72/279 (25%), Positives = 120/279 (43%), Gaps = 39/279 (13%)
Query: 7 SDNSPNHMGFKGLSRHYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYCANTIPD 66
S+N + + + + + +F F+L++ C D++E++D +GRYC +P
Sbjct: 1301 SENQHCNWTIRATTGNTVNYTFLAFDLEHHINCSTDYLELYD---GPRQMGRYCGVDLPP 1357
Query: 67 STDTSSNTAVVRV---------------WW----GSQ--GSAGTSTSPNYPNLNPHGRIY 105
T+S+ V + W+ G + G+ G+ +SP +PN P +
Sbjct: 1358 PGSTTSSKLQVLLLTDGVGRREKGFQMQWFVYGCGGELSGATGSFSSPGFPNRYPPNKEC 1417
Query: 106 EWRITAPEGRQITLTFSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCS--SVNVSSEI 163
W I G I LT + + H CN + + ++ G +SP++ +LC+ S ++
Sbjct: 1418 IWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVLEIYGGPDFHSPRIAQLCTQRSPENPMQV 1477
Query: 164 KSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDG 223
S+GN + + F TD S GF AS A GC G + P G SP Y
Sbjct: 1478 SSTGNELAIRFKTDLSINGRGFNASW----QAVTGGC-----GGIFQAPSGEIHSPNYPS 1528
Query: 224 VRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDC 262
Y N +C W + N + ++F DF LE C
Sbjct: 1529 --PYRSNTDCSWVIRVDR--NHRVLLNFTDFDLEPQDSC 1563
Score = 89.0 bits (219), Expect = 1e-17
Identities = 76/267 (28%), Positives = 116/267 (43%), Gaps = 35/267 (13%)
Query: 27 SFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYCAN-----------------TIPDSTD 69
+F LQ S ++++E+ D T +LG+ C N I S +
Sbjct: 749 NFTHVELQCQSDSSQNYIEVRDGET---LLGKVCGNGTISHIKSITNSVWIRFKIDASVE 805
Query: 70 TSSNTAVVRVWWGSQGSA-GTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRLAT 128
+S AV +V G + + G SP +PN+ P R W I P+ + I L F+ + +
Sbjct: 806 KASFRAVYQVACGDELTGEGVIRSPFFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIGS 865
Query: 129 HLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTAS 188
C +++V + + SP+ +K C + ++ S I S N + V F S GF A
Sbjct: 866 SAHCETDYVEIGSSSILGSPENKKYCGT-DIPSFITSVYNFLYVTFVKSSSTENHGFMAK 924
Query: 189 HTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIY 248
S+ED L G + G SPG+ V Y +NC W + Q N I+
Sbjct: 925 F-SAED--------LACGEILTESTGTIQSPGHPNV--YPHGINCTWHIL--VQPNHLIH 971
Query: 249 IHFEDFYLESHQDCQFDVLEFRVVASE 275
+ FE F+LE H +C D LE SE
Sbjct: 972 LMFETFHLEFHYNCTNDYLEVYDTDSE 998
Score = 89.0 bits (219), Expect = 1e-17
Identities = 76/271 (28%), Positives = 117/271 (43%), Gaps = 40/271 (14%)
Query: 22 HYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYCANTIPDSTDTSSNTAVVRVWW 81
H + FE F+L+ C D++E++D + + LGRYC +IP S +S N+ ++
Sbjct: 968 HLIHLMFETFHLEFHYNCTNDYLEVYDTDSETS-LGRYCGKSIPPSLTSSGNSLMLVFVT 1026
Query: 82 GSQ------------------------GSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQI 117
S GT TSPN+PN P+ +RIT G+ I
Sbjct: 1027 DSDLAYEGFLINYEAISAATACLQDYTDDLGTFTSPNFPNNYPNNWECIYRITVRTGQLI 1086
Query: 118 TLTFSNLRLATHL-SCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFT 176
+ F+N L + + ++ + + +G SP L S N+ I S N + + F +
Sbjct: 1087 AVHFTNFSLEEAIGNYYTDFLEIRDGGYEKSPLLGIFYGS-NLPPTIISHSNKLWLKFKS 1145
Query: 177 DGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWT 236
D GF+A S CGG+L T G F SP Y Y + C W
Sbjct: 1146 DQIDTRSGFSAYWDGSSTG--------CGGNL-TTSSGTFISPNYP--MPYYHSSECYWW 1194
Query: 237 LSNPNQGNSSIYIHFEDFYLESHQDCQFDVL 267
L + + S+ + F+DF+LE H +C D L
Sbjct: 1195 LKSSH--GSAFELEFKDFHLEHHPNCTLDYL 1223
Score = 84.3 bits (207), Expect = 3e-16
Identities = 63/269 (23%), Positives = 115/269 (42%), Gaps = 32/269 (11%)
Query: 27 SFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYCANTIP-------------------DS 67
SF F L++S C +DFVEI + + +G+++GRYC N+ P
Sbjct: 1779 SFISFQLEDSQDCSRDFVEIREGNATGHLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSG 1838
Query: 68 TDTSSNTAVVRVWWGSQ--GSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLR 125
+ T ++++ G+ G SP +P PH Y+W + + +
Sbjct: 1839 SGTGFQATFMKIFGNDNIVGTHGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMD 1898
Query: 126 LATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGF 185
+ +C + + +++G ++ + C + S S+GN++ F++D S GF
Sbjct: 1899 IEEIQNCYYDKLRIYDGPSIHARLIGAYCGTQTES--FSSTGNSLTFHFYSDSSISGKGF 1956
Query: 186 TASHTSSEDADKV---GCCKLCGGSLPNTPEGNFT-SPGYDGVRNYSRNLNCEWTLSNPN 241
+ + D V CGG L F SPG+ +YS ++C W + P
Sbjct: 1957 LLEWFAVDAPDGVLPTIAPGACGGFLRTGDAPVFLFSPGWPD--SYSNRVDCTWLIQAP- 2013
Query: 242 QGNSSIYIHFEDFYLESHQDCQFDVLEFR 270
+S++ ++ +ESH+ C +D L R
Sbjct: 2014 --DSTVELNILSLDIESHRTCAYDSLVIR 2040
Score = 82.0 bits (201), Expect = 2e-15
Identities = 64/267 (23%), Positives = 113/267 (42%), Gaps = 35/267 (13%)
Query: 27 SFEDFNLQNSSGCEKDFVEIWDYHTSGNI-LGRYCANTIPDSTDTSSNTAVVRVW----- 80
+F F L++ C +F++++D +S LGR+C +++P +S N ++
Sbjct: 515 TFTFFRLESMDNCPHEFLQVYDGDSSSAFQLGRFCGSSLPHELLSSDNALYFHLYSEHLR 574
Query: 81 --------WGSQ---------GSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSN 123
W +Q G G+ SP YP P GR W + +T TF
Sbjct: 575 NGRGFTVRWETQQPECGGILTGPYGSIKSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGT 634
Query: 124 LRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYG 183
L L H CN +++ + +G P L K C++ +V ++++G ++ F +D
Sbjct: 635 LSLEHHDDCNKDYLEIRDGPLYQDPLLGKFCTTFSV-PPLQTTGPFARIHFHSDSQISDQ 693
Query: 184 GFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQG 243
GF ++ +S + CGG+ + PEG P G ++R C + + P
Sbjct: 694 GFHITYLTSPSDLR------CGGNYTD-PEGELFLPELSGPFTHTR--QCVYMMKQPQ-- 742
Query: 244 NSSIYIHFEDFYLESHQDCQFDVLEFR 270
I I+F L+ D + +E R
Sbjct: 743 GEQIQINFTHVELQCQSDSSQNYIEVR 769
Score = 80.9 bits (198), Expect = 4e-15
Identities = 69/258 (26%), Positives = 106/258 (41%), Gaps = 45/258 (17%)
Query: 27 SFEDFNLQNSSGCEKDFVEIWDYHTSGNILG-----RYCANTIPDSTDTSSNTAVVRVWW 81
+F F + +S+ CE D+VEI S +ILG +YC IP + N V
Sbjct: 857 NFTVFEIGSSAHCETDYVEIG----SSSILGSPENKKYCGTDIPSFITSVYNFLYVTFVK 912
Query: 82 GSQG----------------------SAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITL 119
S S GT SP +PN+ PHG W I I L
Sbjct: 913 SSSTENHGFMAKFSAEDLACGEILTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLIHL 972
Query: 120 TFSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGS 179
F L H +C ++++ V++ + L + C ++ + SSGN++ ++F TD
Sbjct: 973 MFETFHLEFHYNCTNDYLEVYD--TDSETSLGRYCGK-SIPPSLTSSGNSLMLVFVTDSD 1029
Query: 180 RPYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSN 239
Y GF ++ + A C + L G FTSP + NY N C + ++
Sbjct: 1030 LAYEGFLINYEAISAA--TACLQDYTDDL-----GTFTSPNFP--NNYPNNWECIYRIT- 1079
Query: 240 PNQGNSSIYIHFEDFYLE 257
+ I +HF +F LE
Sbjct: 1080 -VRTGQLIAVHFTNFSLE 1096
Score = 80.9 bits (198), Expect = 4e-15
Identities = 71/249 (28%), Positives = 109/249 (43%), Gaps = 39/249 (15%)
Query: 9 NSPNHMGFKGLSRHYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYCAN---TIP 65
++PN G +S H FEDF L++ C+ D +E G ++ R C T+P
Sbjct: 2604 SNPNQ-GNSSISIH-----FEDFYLESHQDCQFDVLEFRVGDADGPLMWRLCGPSKPTLP 2657
Query: 66 DSTDTS-------SNTAVVRVWWGSQ-----------GSAGTSTSPNYPNLNPHGRIYEW 107
S +N V + + ++ G +G TSPNYPN
Sbjct: 2658 LVIPYSQVWIHFVTNERVEHIGFHAKYSFTDCGGIQIGDSGVITSPNYPNAYDSLTHCSS 2717
Query: 108 RITAPEGRQITLTFSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSG 167
+ AP+G ITLTFS+ + H +C + V V NG SP + + C + N + I+S
Sbjct: 2718 LLEAPQGHTITLTFSDFDIEPHTTCAWDSVTVRNGGSPESPIIGQYCGNSNPRT-IQSGS 2776
Query: 168 NTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNY 227
N + V F +D S GGF A+ + +GC G + ++ G SP + +N+
Sbjct: 2777 NQLVVTFNSDHSLQGGGFYATW----NTQTLGC-----GGIFHSDNGTIRSPHWP--QNF 2825
Query: 228 SRNLNCEWT 236
N C WT
Sbjct: 2826 PENSRCSWT 2834
Score = 79.0 bits (193), Expect = 1e-14
Identities = 67/264 (25%), Positives = 114/264 (43%), Gaps = 43/264 (16%)
Query: 28 FEDFNLQNSSGCEKDFVEIWDYHTSGN-ILGRYCANTIPDSTDTSSNTAVVRVWW--GSQ 84
F+DF+L++ C D++ ++D +S + +L + C + P +S ++ +++ G Q
Sbjct: 1207 FKDFHLEHHPNCTLDYLAVYDGPSSNSHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQ 1266
Query: 85 GSA-------------------GTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLR 125
G G S YPN + W I A G + TF
Sbjct: 1267 GRGFKAEYRQTCENVVIVNQTYGILESIGYPNPYSENQHCNWTIRATTGNTVNYTFLAFD 1326
Query: 126 LATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDG-SRPYGG 184
L H++C+++++ +++G R Q+ + C V++ ++ + ++V+ TDG R G
Sbjct: 1327 LEHHINCSTDYLELYDGPR----QMGRYCG-VDLPPPGSTTSSKLQVLLLTDGVGRREKG 1381
Query: 185 FTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGN 244
F CGG L G+F+SPG+ Y N C W +
Sbjct: 1382 FQMQWFVYG----------CGGELSGAT-GSFSSPGFPN--RYPPNKECIWYIRT--DPG 1426
Query: 245 SSIYIHFEDFYLESHQDCQFDVLE 268
SSI + DF +E H C FDVLE
Sbjct: 1427 SSIQLTIHDFDVEYHSRCNFDVLE 1450
Score = 79.0 bits (193), Expect = 1e-14
Identities = 56/187 (29%), Positives = 91/187 (48%), Gaps = 13/187 (6%)
Query: 86 SAGTSTSPNYPNLN-PHGRIYEWRITAPEGRQITLTFSNLRLATHLSCNSEHVIVFNGIR 144
S+G TSP Y + P+ + IT + + I L FS+ + SC+ +++ +++G
Sbjct: 3044 SSGIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVVPSTSCSHDYLAIYDGAN 3103
Query: 145 SNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKLC 204
++ P L K C S +KSS N+M ++F TD + G+ S + +G + C
Sbjct: 3104 TSDPLLGKFCGSKR-PPNVKSSNNSMLLVFKTDSFQTAKGWKMSFRQT-----LGPQQGC 3157
Query: 205 GGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLE---SHQD 261
GG L + F SP D Y +NLNC W + P N I++ F F LE + Q
Sbjct: 3158 GGYLTGS-NNTFASPDSDSNGMYDKNLNCVWIIIAP--VNKVIHLTFNTFALEAASTRQR 3214
Query: 262 CQFDVLE 268
C +D ++
Sbjct: 3215 CLYDYVK 3221
Score = 77.8 bits (190), Expect = 3e-14
Identities = 82/305 (26%), Positives = 125/305 (40%), Gaps = 39/305 (12%)
Query: 28 FEDFNLQNSSG-CEKDFVEIWDY-HTSGNILGRYCANTIPDSTDTSSNTAVVRV------ 79
F +F+L+ + G DF+EI D + +LG + + +P + + SN ++
Sbjct: 1090 FTNFSLEEAIGNYYTDFLEIRDGGYEKSPLLGIFYGSNLPPTIISHSNKLWLKFKSDQID 1149
Query: 80 --------WWGSQG--------SAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSN 123
W GS S+GT SPNYP H W + + G L F +
Sbjct: 1150 TRSGFSAYWDGSSTGCGGNLTTSSGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKD 1209
Query: 124 LRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYG 183
L H +C +++ V++G SNS L +LC I+SSG++M + TD +
Sbjct: 1210 FHLEHHPNCTLDYLAVYDGPSSNSHLLTQLCGD-EKPPLIRSSGDSMFIKLRTDEGQQGR 1268
Query: 184 GFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQG 243
GF A + + C+ + N G S GY YS N +C WT+ G
Sbjct: 1269 GFKAEYRQT--------CE--NVVIVNQTYGILESIGYP--NPYSENQHCNWTI-RATTG 1315
Query: 244 NSSIYIHFEDFYLESHQDCQFDVLEFRVVASEHWKVPFSLISRLSGWSECSLERNLFADG 303
N+ Y F F LE H +C D LE + + + + L+ L DG
Sbjct: 1316 NTVNYT-FLAFDLEHHINCSTDYLELYDGPRQMGRYCGVDLPPPGSTTSSKLQVLLLTDG 1374
Query: 304 TGLRE 308
G RE
Sbjct: 1375 VGRRE 1379
Score = 77.8 bits (190), Expect = 3e-14
Identities = 72/274 (26%), Positives = 115/274 (41%), Gaps = 49/274 (17%)
Query: 22 HYLTNSFEDFNLQNSSGCEKDFVEIWDY-HTSGNILGRYCANTIPDSTDTSSNTAVVRVW 80
+++T SF F L+ S+ C +DFVEI D H + GRYC +P + S+ +R
Sbjct: 1658 NHITLSFTHFELERSTTCARDFVEILDGGHEDAPLRGRYCGTDMPHPITSFSSALTLRFV 1717
Query: 81 WGSQGSAG----------------------TSTSPNYPNLNPHGRIYEWRITAPEGRQIT 118
S SAG SP YP++ P W I + G ++
Sbjct: 1718 SDSSISAGGFHTTVTASVSACGGTFYMAEGIFNSPGYPDIYPPNVECVWNIVSSPGNRLQ 1777
Query: 119 LTFSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSS---VNVSSEIKSSGNTMKVIFF 175
L+F + +L C+ + V + G + + + C + +N SS + G+T+ V F
Sbjct: 1778 LSFISFQLEDSQDCSRDFVEIREG-NATGHLVGRYCGNSFPLNYSSIV---GHTLWVRFI 1833
Query: 176 TDGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEW 235
+DGS GF A+ K+ G G SP + NY N N +W
Sbjct: 1834 SDGSGSGTGFQATF-----------MKIFGNDNIVGTHGKVASPFWP--ENYPHNSNYQW 1880
Query: 236 TLSNPNQGNSSIYIH--FEDFYLESHQDCQFDVL 267
T++ N+S +H + +E Q+C +D L
Sbjct: 1881 TVN----VNASHVVHGRILEMDIEEIQNCYYDKL 1910
Score = 76.6 bits (187), Expect = 7e-14
Identities = 62/186 (33%), Positives = 92/186 (49%), Gaps = 20/186 (10%)
Query: 86 SAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSN-LRLATHLSCNSEHVIVFNGIR 144
SAG TSPN+P+ P W + AP +I L F + + +C S ++ + +G+
Sbjct: 2228 SAGYVTSPNHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIEVTPNCTSNYLELRDGVD 2287
Query: 145 SNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKLC 204
S++P L K C + SS+ SSG M + F +D S + GF A ++ ++ C
Sbjct: 2288 SDAPILSKFCGTSLPSSQ-WSSGEVMYLRFRSDNSPTHVGFKAKYSIAQ----------C 2336
Query: 205 GGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIY--IHFEDFYLESHQDC 262
GG +P G S G+ + Y NL CEW L QG S Y I FEDF L++ C
Sbjct: 2337 GGRVPG-QSGVVESIGHPTL-PYRDNLFCEWHL----QGLSGHYLTISFEDFNLQNSSGC 2390
Query: 263 QFDVLE 268
+ D +E
Sbjct: 2391 EKDFVE 2396
Score = 74.7 bits (182), Expect = 3e-13
Identities = 53/175 (30%), Positives = 81/175 (46%), Gaps = 14/175 (8%)
Query: 88 GTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRLATHLSCNSEHVIVFNGIRSNS 147
G SP +P+ + + +TAP+ I+L F +L + + C ++ + V NG SNS
Sbjct: 3404 GNLRSPGWPDNYDNDKDCTVTLTAPQNHTISLFFHSLGIENSVECRNDFLEVRNGSNSNS 3463
Query: 148 PQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKLCGGS 207
P L K C ++ + + + S N + + F +D G+ TSS CGG+
Sbjct: 3464 PLLGKYCGTL-LPNPVFSQNNELYLRFKSDSVTSDRGYEIIWTSSPSG--------CGGT 3514
Query: 208 LPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDC 262
L G+FTSPGY G Y N CEW L P + I+F ++ DC
Sbjct: 3515 LYG-DRGSFTSPGYPG--TYPNNTYCEWVLVAP--AGRLVTINFYFISIDDPGDC 3564
Score = 73.9 bits (180), Expect = 4e-13
Identities = 45/187 (24%), Positives = 80/187 (42%), Gaps = 23/187 (12%)
Query: 22 HYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGN-ILGRYCANTIPDSTDTSSNTAVVR-- 78
H ++ F ++NS C DF+E+ + S + +LG+YC +P+ + +N +R
Sbjct: 3431 HTISLFFHSLGIENSVECRNDFLEVRNGSNSNSPLLGKYCGTLLPNPVFSQNNELYLRFK 3490
Query: 79 ------------VWWGSQ--------GSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQIT 118
+W S G G+ TSP YP P+ EW + AP GR +T
Sbjct: 3491 SDSVTSDRGYEIIWTSSPSGCGGTLYGDRGSFTSPGYPGTYPNNTYCEWVLVAPAGRLVT 3550
Query: 119 LTFSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDG 178
+ F + + C ++ +++G ++SP C + +S N + + F D
Sbjct: 3551 INFYFISIDDPGDCVQNYLTLYDGPNASSPSSGPYCGGDTSIAPFVASSNQVFIKFHADY 3610
Query: 179 SRPYGGF 185
+R F
Sbjct: 3611 ARRPSAF 3617
Score = 72.8 bits (177), Expect = 1e-12
Identities = 65/270 (24%), Positives = 106/270 (39%), Gaps = 48/270 (17%)
Query: 27 SFEDFNLQNSSGCEKDFVEIW---DYHTSGNILGRYCANTIPDS---------------- 67
+ DF+++ S C D +EI+ D+H+ + + C P++
Sbjct: 1432 TIHDFDVEYHSRCNFDVLEIYGGPDFHSPR--IAQLCTQRSPENPMQVSSTGNELAIRFK 1489
Query: 68 TDTSSNTAVVRVWWGS---------QGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQIT 118
TD S N W + Q +G SPNYP+ W I ++
Sbjct: 1490 TDLSINGRGFNASWQAVTGGCGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIRVDRNHRVL 1549
Query: 119 LTFSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDG 178
L F++ L SC ++ ++G+ S +L + C +++ I SSGN++ + F +
Sbjct: 1550 LNFTDFDLEPQDSC----IMAYDGLSSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGP 1605
Query: 179 SRPYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLS 238
SR GF A + CGG + + +SP + NY N NC W +
Sbjct: 1606 SRQNRGFRAQFRQA-----------CGGHILTSSFDTVSSPRFPA--NYPNNQNCSWIIQ 1652
Query: 239 NPNQGNSSIYIHFEDFYLESHQDCQFDVLE 268
N I + F F LE C D +E
Sbjct: 1653 AQPPLN-HITLSFTHFELERSTTCARDFVE 1681
Score = 66.6 bits (161), Expect = 7e-11
Identities = 50/165 (30%), Positives = 78/165 (47%), Gaps = 16/165 (9%)
Query: 107 WRITAPEGRQITLTFSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSS 166
W I G+ + +TF+ RL + +C E + V++G S++ QL + C S ++ E+ SS
Sbjct: 502 WVIKTEMGKVLRITFTFFRLESMDNCPHEFLQVYDGDSSSAFQLGRFCGS-SLPHELLSS 560
Query: 167 GNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRN 226
N + +++ R GFT + + CGG L P G+ SPGY G N
Sbjct: 561 DNALYFHLYSEHLRNGRGFTVRWETQQPE--------CGGILTG-PYGSIKSPGYPG--N 609
Query: 227 YSRNLNCEW-TLSNPNQGNSSIYIHFEDFYLESHQDCQFDVLEFR 270
Y +C W +++P + + F LE H DC D LE R
Sbjct: 610 YPPGRDCVWIVVTSP---DLLVTFTFGTLSLEHHDDCNKDYLEIR 651
Score = 63.2 bits (152), Expect = 8e-10
Identities = 73/292 (25%), Positives = 120/292 (41%), Gaps = 48/292 (16%)
Query: 28 FEDFNLQNSSGCEKDFVEIWD-YHTSGNILGRYCANTIPDSTDTSSNTAVV--------- 77
F DF++ S+ C D++ I+D +TS +LG++C + P + +S+N+ ++
Sbjct: 3080 FSDFDVVPSTSCSHDYLAIYDGANTSDPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSFQT 3139
Query: 78 -RVWWGS--------QGSAGTSTSPNYPNLNP---HGRIYE------WRITAPEGRQITL 119
+ W S QG G T N +P +Y+ W I AP + I L
Sbjct: 3140 AKGWKMSFRQTLGPQQGCGGYLTGSNNTFASPDSDSNGMYDKNLNCVWIIIAPVNKVIHL 3199
Query: 120 TFSNLRL---ATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFT 176
TF+ L +T C ++V +++G N+ C S V + SSGN + V F +
Sbjct: 3200 TFNTFALEAASTRQRCLYDYVKLYDGDSENANLAGTFCGS-TVPAPFISSGNFLTVQFIS 3258
Query: 177 DGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPNT-PEGNFTSP-GYDGVRNYSRNLNCE 234
D + GF A++T + CGG+ T N +SP D +S C
Sbjct: 3259 DLTLEREGFNATYTIMD--------MPCGGTYNATWTPQNISSPNSSDPDVPFS---ICT 3307
Query: 235 WTLSNPNQGNSSIYIHFEDFYLESHQDCQFDVLEFRVVASEHWKVPFSLISR 286
W + +P I + + QDC + L+ + H F R
Sbjct: 3308 WVIDSPPHQQVKITVWALQL---TSQDCTQNYLQLQDSPQGHGNSRFQFCGR 3356
Score = 62.4 bits (150), Expect = 1e-09
Identities = 66/264 (25%), Positives = 107/264 (40%), Gaps = 46/264 (17%)
Query: 22 HYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGN-ILGRYCANTIPDSTDTSSNTAVVR-- 78
H +T +F DF+++ + C D V + + + + I+G+YC N+ P + + SN VV
Sbjct: 2725 HTITLTFSDFDIEPHTTCAWDSVTVRNGGSPESPIIGQYCGNSNPRTIQSGSNQLVVTFN 2784
Query: 79 -----------VWWGSQ---------GSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQIT 118
W +Q GT SP++P P W + + +
Sbjct: 2785 SDHSLQGGGFYATWNTQTLGCGGIFHSDNGTIRSPHWPQNFPENSRCSWTAITHKSKHLE 2844
Query: 119 LTFSN--LRLATHLSCNSEHVIVFNGIRS-NSPQLEKLCSSVNVSSEIKSSGNTMKVIFF 175
++F N L + C + V V+ G + L C +V I S NT +F
Sbjct: 2845 ISFDNNFLIPSGDGQCQNSFVKVWAGTEEVDKALLATGCGNVAPGPVITPS-NTFTAVFQ 2903
Query: 176 TDGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEW 235
+ P GF+AS S CG + P G SP Y + Y N+NC +
Sbjct: 2904 SQ-EAPAQGFSASFVSR-----------CGSNFTG-PSGYIISPNYP--KQYDNNMNCTY 2948
Query: 236 TL-SNPNQGNSSIYIHFEDFYLES 258
+ +NP S + + F F+LE+
Sbjct: 2949 VIEANP---LSVVLLTFVSFHLEA 2969
Score = 62.0 bits (149), Expect = 2e-09
Identities = 48/161 (29%), Positives = 73/161 (45%), Gaps = 18/161 (11%)
Query: 92 SPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRLATHLSCNSEHVIVFNGIRSNSPQLE 151
SP +P+ + W I AP+ + L +L + +H +C + +++ +G + + QL
Sbjct: 1993 SPGWPDSYSNRVDCTWLIQAPDST-VELNILSLDIESHRTCAYDSLVIRDGDNNLAQQLA 2051
Query: 152 KLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPNT 211
LC + I+S+G M + F +D S GF AS S CGG L +
Sbjct: 2052 VLCGR-EIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFHKS-----------CGGYL-HA 2098
Query: 212 PEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFE 252
G TSP Y Y NLNC W + Q +I +HFE
Sbjct: 2099 DRGIITSPKYP--ETYPSNLNCSWHVL--VQSGLTIAVHFE 2135
Score = 59.7 bits (143), Expect = 9e-09
Identities = 67/270 (24%), Positives = 107/270 (39%), Gaps = 47/270 (17%)
Query: 24 LTNSFEDFNLQNSSGCEKDFVEIWDYHTSGN-ILGRYCANTIPDSTDTSSNTAVVRVWWG 82
+T +F +L++ C KD++EI D + +LG++C T+ A +
Sbjct: 628 VTFTFGTLSLEHHDDCNKDYLEIRDGPLYQDPLLGKFCTTFSVPPLQTTGPFARIHFHSD 687
Query: 83 SQGS-----------------AGTSTSPN----YPNLN---PHGRIYEWRITAPEGRQIT 118
SQ S G T P P L+ H R + + P+G QI
Sbjct: 688 SQISDQGFHITYLTSPSDLRCGGNYTDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQIQ 747
Query: 119 LTFSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDG 178
+ F+++ L C S+ + +R L K+C + + S IKS N++ + F D
Sbjct: 748 INFTHV----ELQCQSDSSQNYIEVRDGETLLGKVCGNGTI-SHIKSITNSVWIRFKIDA 802
Query: 179 SRPYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLS 238
S F A + + CG L T EG SP + V Y C WT+
Sbjct: 803 SVEKASFRAVYQVA-----------CGDEL--TGEGVIRSPFFPNV--YPGERTCRWTIH 847
Query: 239 NPNQGNSSIYIHFEDFYLESHQDCQFDVLE 268
P + I ++F F + S C+ D +E
Sbjct: 848 QPQ--SQVILLNFTVFEIGSSAHCETDYVE 875
Score = 54.7 bits (130), Expect = 3e-07
Identities = 56/196 (28%), Positives = 82/196 (41%), Gaps = 26/196 (13%)
Query: 88 GTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRLATH--LSCN-SEHVIVFNGIR 144
G TSP YP P W + G I + F + SCN +++++ NG
Sbjct: 2101 GIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQGDYLVLRNGPD 2160
Query: 145 SNSPQL------EKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKV 198
SP L C S + SS + +S N M V F +D S GF + + A
Sbjct: 2161 ICSPPLGPPGGNGHFCGS-HASSTLFTSDNQMFVQFISDHSNEGQGFKIKYEAKSLA--- 2216
Query: 199 GCCKLCGGSL---PNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFED-F 254
CGG++ G TSP + NY + +C W L+ P + + I + FED F
Sbjct: 2217 -----CGGNVYIHDADSAGYVTSPNHP--HNYPPHADCIWILAAPPE--TRIQLQFEDRF 2267
Query: 255 YLESHQDCQFDVLEFR 270
+E +C + LE R
Sbjct: 2268 DIEVTPNCTSNYLELR 2283
Score = 48.9 bits (115), Expect = 2e-05
Identities = 47/187 (25%), Positives = 80/187 (42%), Gaps = 20/187 (10%)
Query: 88 GTSTSPNYPNLNPHGRIY--EWRITAPE--GRQITLTFSNLRLATHLSCNSEHVIVFNGI 143
G TSP Y + + R EW ++ P I++ F + L +H C + V+ F
Sbjct: 2580 GNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSISIHFEDFYLESHQDCQFD-VLEFRVG 2638
Query: 144 RSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKL 203
++ P + +LC + + + + + F T+ + GF A ++ ++
Sbjct: 2639 DADGPLMWRLCGPSKPTLPLVIPYSQVWIHFVTNERVEHIGFHAKYSFTD---------- 2688
Query: 204 CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
CGG + G TSP Y Y +C L P QG++ I + F DF +E H C
Sbjct: 2689 CGG-IQIGDSGVITSPNYPNA--YDSLTHCSSLLEAP-QGHT-ITLTFSDFDIEPHTTCA 2743
Query: 264 FDVLEFR 270
+D + R
Sbjct: 2744 WDSVTVR 2750
>gi|222537750 ankyrin repeat domain 30B [Homo sapiens]
Length = 1392
Score = 239 bits (610), Expect = 6e-63
Identities = 118/145 (81%), Positives = 127/145 (87%)
Query: 522 LSQSHATEQPEGTSEGTPDEAAPLAERTPDMAESLVEKPPDEAAPLVEGTADKIQCLGKA 581
L ++ PEGTS GTPDEAAPLAERTPD AESL+EK PDEAA LVEGT+ KIQCLGKA
Sbjct: 264 LPKNPQNTNPEGTSTGTPDEAAPLAERTPDTAESLLEKTPDEAARLVEGTSAKIQCLGKA 323
Query: 582 TSGKFEQSAEETPKKIMRTAKETSKKFAWPAKERPRKITWEEKETSVKTECVAGVIPNKT 641
TSGKFEQS EETP+KI+R KETS+KF+WPAKER RKITWEEKETSVKTECVAGV PNKT
Sbjct: 324 TSGKFEQSTEETPRKILRPTKETSEKFSWPAKERSRKITWEEKETSVKTECVAGVTPNKT 383
Query: 642 EVLEKGTSEMLTCPTKETSTKASTN 666
EVLEKGTS M+ CPTKETSTKASTN
Sbjct: 384 EVLEKGTSNMIACPTKETSTKASTN 408
>gi|115495445 ankyrin repeat domain 30A [Homo sapiens]
Length = 1341
Score = 196 bits (499), Expect = 4e-50
Identities = 112/201 (55%), Positives = 123/201 (61%), Gaps = 56/201 (27%)
Query: 522 LSQSHATEQPEGTSEGTPDEAAPLAERTPDMAESLVEKPPDEAAPLVE------------ 569
LS++H PEGTS GTPDEAAPLAERTPD AESLVEK PDEAAPLVE
Sbjct: 208 LSKNHQNTNPEGTSAGTPDEAAPLAERTPDTAESLVEKTPDEAAPLVERTPDTAESLVEK 267
Query: 570 ----------GTADKIQCLGKATSGKFEQSAEETPKKIMRTAKETSKKFAWP-------- 611
GT+DKIQCL KATSGKFEQSAEETP++I AKETS+KF WP
Sbjct: 268 TPDEAASLVEGTSDKIQCLEKATSGKFEQSAEETPREITSPAKETSEKFTWPAKGRPRKI 327
Query: 612 --------------------------AKERPRKITWEEKETSVKTECVAGVIPNKTEVLE 645
AK RPRKI WE+KET VKT CVA V NKT+VLE
Sbjct: 328 AWEKKEDTPREIMSPAKETSEKFTWAAKGRPRKIAWEKKETPVKTGCVARVTSNKTKVLE 387
Query: 646 KGTSEMLTCPTKETSTKASTN 666
KG S+M+ CPTKE+STKAS N
Sbjct: 388 KGRSKMIACPTKESSTKASAN 408
>gi|239757619 PREDICTED: similar to hCG1644292 [Homo sapiens]
Length = 118
Score = 185 bits (469), Expect = 1e-46
Identities = 93/120 (77%), Positives = 105/120 (87%), Gaps = 2/120 (1%)
Query: 552 MAESLVEKPPDEAAPLVEGTADKIQCLGKATSGKFEQSAEETPKKIMRTAKETSKKFAWP 611
MAESLVE+ PDEAAPLVEGT+D++QCLGK SGK EQSA ETP+KI R KETS+KFAWP
Sbjct: 1 MAESLVERTPDEAAPLVEGTSDEVQCLGKTISGKTEQSARETPRKITRPVKETSEKFAWP 60
Query: 612 AKERPRKITWEEKETSVKTECVAGVIPNKTEVLEKGTSEMLTCPTKETSTKASTNGKMLE 671
+ERP K TWEEKETSVKTECVAGV NK EVLE+GT++M+TCPTK T+TKASTNGKMLE
Sbjct: 61 -QERPTKTTWEEKETSVKTECVAGVTSNKIEVLEEGTAKMITCPTK-TATKASTNGKMLE 118
>gi|239752110 PREDICTED: hypothetical protein XP_002348113 [Homo
sapiens]
Length = 118
Score = 185 bits (469), Expect = 1e-46
Identities = 93/120 (77%), Positives = 105/120 (87%), Gaps = 2/120 (1%)
Query: 552 MAESLVEKPPDEAAPLVEGTADKIQCLGKATSGKFEQSAEETPKKIMRTAKETSKKFAWP 611
MAESLVE+ PDEAAPLVEGT+D++QCLGK SGK EQSA ETP+KI R KETS+KFAWP
Sbjct: 1 MAESLVERTPDEAAPLVEGTSDEVQCLGKTISGKTEQSARETPRKITRPVKETSEKFAWP 60
Query: 612 AKERPRKITWEEKETSVKTECVAGVIPNKTEVLEKGTSEMLTCPTKETSTKASTNGKMLE 671
+ERP K TWEEKETSVKTECVAGV NK EVLE+GT++M+TCPTK T+TKASTNGKMLE
Sbjct: 61 -QERPTKTTWEEKETSVKTECVAGVTSNKIEVLEEGTAKMITCPTK-TATKASTNGKMLE 118
>gi|239743843 PREDICTED: hypothetical protein XP_002342968 [Homo
sapiens]
Length = 139
Score = 169 bits (429), Expect = 6e-42
Identities = 83/111 (74%), Positives = 95/111 (85%), Gaps = 1/111 (0%)
Query: 552 MAESLVEKPPDEAAPLVEGTADKIQCLGKATSGKFEQSAEETPKKIMRTAKETSKKFAWP 611
MAESLVE+ PDEAAPLVEGT+D++QCLGK SGK E+SA ETP+KI R KETS+KFAWP
Sbjct: 1 MAESLVERTPDEAAPLVEGTSDEVQCLGKTISGKIEESAGETPRKITRPVKETSEKFAWP 60
Query: 612 AKERPRKITWEEKETSVKTECVAGVIPNKTEVLEKGTSEMLTCPTKETSTK 662
+ERP K TWEEKETSVKTECVAGV NKTEVLE+GTS+M+TCPTK+ K
Sbjct: 61 -QERPTKTTWEEKETSVKTECVAGVTSNKTEVLEEGTSKMITCPTKKQLQK 110
>gi|239743812 PREDICTED: similar to hCG1644292 [Homo sapiens]
Length = 139
Score = 169 bits (429), Expect = 6e-42
Identities = 83/111 (74%), Positives = 95/111 (85%), Gaps = 1/111 (0%)
Query: 552 MAESLVEKPPDEAAPLVEGTADKIQCLGKATSGKFEQSAEETPKKIMRTAKETSKKFAWP 611
MAESLVE+ PDEAAPLVEGT+D++QCLGK SGK E+SA ETP+KI R KETS+KFAWP
Sbjct: 1 MAESLVERTPDEAAPLVEGTSDEVQCLGKTISGKIEESAGETPRKITRPVKETSEKFAWP 60
Query: 612 AKERPRKITWEEKETSVKTECVAGVIPNKTEVLEKGTSEMLTCPTKETSTK 662
+ERP K TWEEKETSVKTECVAGV NKTEVLE+GTS+M+TCPTK+ K
Sbjct: 61 -QERPTKTTWEEKETSVKTECVAGVTSNKTEVLEEGTSKMITCPTKKQLQK 110
>gi|239758143 PREDICTED: similar to hCG1644292 [Homo sapiens]
Length = 115
Score = 164 bits (414), Expect = 3e-40
Identities = 81/111 (72%), Positives = 93/111 (83%), Gaps = 1/111 (0%)
Query: 552 MAESLVEKPPDEAAPLVEGTADKIQCLGKATSGKFEQSAEETPKKIMRTAKETSKKFAWP 611
MAESLVE+ EAAPLVEGT+D++QCLGK SGK E+SA ETP+KI R KETS+KFAWP
Sbjct: 1 MAESLVERTQHEAAPLVEGTSDEVQCLGKTISGKIEESAGETPRKITRPVKETSEKFAWP 60
Query: 612 AKERPRKITWEEKETSVKTECVAGVIPNKTEVLEKGTSEMLTCPTKETSTK 662
+ERP K TWEEKETSVKTECVAGV NKTEVLE+GTS+M+TCPTK+ K
Sbjct: 61 -QERPTKTTWEEKETSVKTECVAGVTSNKTEVLEEGTSKMITCPTKKQLQK 110
>gi|22547221 tolloid-like 1 [Homo sapiens]
Length = 1013
Score = 101 bits (252), Expect = 2e-21
Identities = 82/293 (27%), Positives = 129/293 (44%), Gaps = 56/293 (19%)
Query: 27 SFEDFNLQNSSGCEKDFVEIWD-YHTSGNILGRYCANTIPD---STDT--------SSN- 73
+F +L SS C D++E+ D Y +LGR+C + +P+ STD+ SSN
Sbjct: 390 NFTTMDLYKSSLCWYDYIEVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNW 449
Query: 74 -----TAVVRVWWGSQ--GSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRL 126
AV G + + G SPNYP+ + W+IT E + LTF + +
Sbjct: 450 VGKGFAAVYEAICGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEI 509
Query: 127 ATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFT 186
H +C +++ V +G NSP + + C + +I+S+ NT+ + F +DG+ GF
Sbjct: 510 ERHDNCAYDYLEVRDGTSENSPLIGRFCG-YDKPEDIRSTSNTLWMKFVSDGTVNKAGFA 568
Query: 187 ASHTSSED----ADKVGC---------------------------CKLCGGSLPNTPEGN 215
A+ ED D+ GC C+ G L G
Sbjct: 569 ANFFKEEDECAKPDRGGCEQRCLNTLGSYQCACEPGYELGPDRRSCEAACGGLLTKLNGT 628
Query: 216 FTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQFDVLE 268
T+PG+ + Y N NC W + P Q I + FE F LE ++ C++D +E
Sbjct: 629 ITTPGWP--KEYPPNKNCVWQVVAPTQ--YRISVKFEFFELEGNEVCKYDYVE 677
Score = 101 bits (252), Expect = 2e-21
Identities = 76/272 (27%), Positives = 123/272 (45%), Gaps = 33/272 (12%)
Query: 1 MYLRFRSDNSPNHMGFKGLSRHYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRY- 59
M + F+SDN+ + GFK H+ ++ +D +++ GC+ + V N +G Y
Sbjct: 708 MRIEFKSDNTVSKKGFKA---HFFSD--KDECSKDNGGCQHECV---------NTMGSYM 753
Query: 60 --CANTIPDSTDTSSNTAVVRVWWGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQI 117
C N D + +G TSPN+P+ P + W I+A G +I
Sbjct: 754 CQCRNGFV-LHDNKHDCKEAECEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRI 812
Query: 118 TLTFSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTD 177
L FS + H C +H+ VF+G SP L +LC + + + ++GN M V F +D
Sbjct: 813 KLAFSEFEIEQHQECAYDHLEVFDGETEKSPILGRLCGN-KIPDPLVATGNKMFVRFVSD 871
Query: 178 GSRPYGGFTASHTSSEDADKVGCCKLCGGSL-PNTPEGNFTSPGYDGVRNYSRNLNCEWT 236
S GF A+H++ CGG L + + S G NY ++CEW
Sbjct: 872 ASVQRKGFQATHSTE-----------CGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWL 920
Query: 237 LSNPNQGNSSIYIHFEDFYLESHQDCQFDVLE 268
L ++ S + + F+ F +E DC +D +E
Sbjct: 921 L--VSERGSRLELSFQTFEVEEEADCGYDYVE 950
Score = 70.5 bits (171), Expect = 5e-12
Identities = 61/233 (26%), Positives = 95/233 (40%), Gaps = 40/233 (17%)
Query: 88 GTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRLATHLSCNSEHVIVFNGIRSNS 147
GT T+P +P P + W++ AP +I++ F L + C ++V +++G+ S S
Sbjct: 627 GTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYDYVEIWSGLSSES 686
Query: 148 PQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSED---ADKVGCCKLC 204
K C + V I S N M++ F +D + GF A S +D D GC C
Sbjct: 687 KLHGKFCGA-EVPEVITSQFNNMRIEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQHEC 745
Query: 205 GGSLP----------------------------NTPEGNFTSPGYDGVRNYSRNLNCEWT 236
++ ++P G TSP + Y C W
Sbjct: 746 VNTMGSYMCQCRNGFVLHDNKHDCKEAECEQKIHSPSGLITSPNWPD--KYPSRKECTWE 803
Query: 237 LSNPNQGNSSIYIHFEDFYLESHQDCQFDVLEFRVVASEHWKVPFSLISRLSG 289
+S I + F +F +E HQ+C +D LE V E K P ++ RL G
Sbjct: 804 IS--ATPGHRIKLAFSEFEIEQHQECAYDHLE--VFDGETEKSP--ILGRLCG 850
Score = 67.8 bits (164), Expect = 3e-11
Identities = 54/209 (25%), Positives = 90/209 (43%), Gaps = 21/209 (10%)
Query: 84 QGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRLATHLSCNSEHVIVFNGI 143
Q S G +SP +PN P WR++ G +I L F+ + L C +++ V +G
Sbjct: 354 QESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIEVRDGY 413
Query: 144 RSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKL 203
SP L + C + + S+ + M + F + + GF A + + +
Sbjct: 414 WRKSPLLGRFCGD-KLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEA-----------I 461
Query: 204 CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
CGG + EG SP Y +Y C W ++ + + + F+ F +E H +C
Sbjct: 462 CGGEIRKN-EGQIQSPNYPD--DYRPMKECVWKITVSE--SYHVGLTFQSFEIERHDNCA 516
Query: 264 FDVLEFRVVASEHWKVPFSLISRLSGWSE 292
+D LE R SE+ LI R G+ +
Sbjct: 517 YDYLEVRDGTSEN----SPLIGRFCGYDK 541
Score = 61.2 bits (147), Expect = 3e-09
Identities = 48/194 (24%), Positives = 83/194 (42%), Gaps = 25/194 (12%)
Query: 22 HYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGN-ILGRYCANTIPDSTDTSSNTAVVRVW 80
H + +F +F ++ C D +E++D T + ILGR C N IPD + N VR
Sbjct: 810 HRIKLAFSEFEIEQHQECAYDHLEVFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFV 869
Query: 81 W-------GSQGSAGTS---------------TSPNYPNLNPHGRI-YEWRITAPEGRQI 117
G Q + T + + + N G++ EW + + G ++
Sbjct: 870 SDASVQRKGFQATHSTECGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRL 929
Query: 118 TLTFSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTD 177
L+F + C ++V +F+G+ S + L + C S EI S G+++ + F TD
Sbjct: 930 ELSFQTFEVEEEADCGYDYVELFDGLDSTAVGLGRFCGS-GPPEEIYSIGDSVLIHFHTD 988
Query: 178 GSRPYGGFTASHTS 191
+ GF + S
Sbjct: 989 DTINKKGFHIRYKS 1002
>gi|6912724 tolloid-like 2 [Homo sapiens]
Length = 1015
Score = 96.7 bits (239), Expect = 6e-20
Identities = 84/296 (28%), Positives = 124/296 (41%), Gaps = 58/296 (19%)
Query: 27 SFEDFNLQNSSGCEKDFVEIWD-YHTSGNILGRYCANTIPD---STDT-------SSNTA 75
+F +L S C D+VE+ D Y +LGR+C + IP+ STD+ SS+
Sbjct: 392 NFTSMDLFKSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNI 451
Query: 76 VVRVWWGSQGS---------AGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRL 126
+ + ++ + + AG SPNYP+ + WRIT EG + LTF +
Sbjct: 452 LGKGFFAAYEATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEI 511
Query: 127 ATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFT 186
H SC +++ V +G S + C ++KSS N + + F +DGS GF
Sbjct: 512 ERHDSCAYDYLEVRDGPTEESALIGHFC-GYEKPEDVKSSSNRLWMKFVSDGSINKAGFA 570
Query: 187 ASHTSSED--------------------------------ADKVGCCKLCGGSLPNTPEG 214
A+ D ADK C CGG + G
Sbjct: 571 ANFFKEVDECSWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKL-NG 629
Query: 215 NFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQFDVLEFR 270
TSPG+ + Y N NC W + P Q I + FE F LE + C++D +E R
Sbjct: 630 TITSPGWP--KEYPTNKNCVWQVVAPAQ--YRISLQFEVFELEGNDVCKYDFVEVR 681
Score = 87.8 bits (216), Expect = 3e-17
Identities = 65/269 (24%), Positives = 116/269 (43%), Gaps = 27/269 (10%)
Query: 1 MYLRFRSDNSPNHMGFKGLSRHYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYC 60
M + F+SDN+ + GF+ H+ ++ +D +++ GC+ + V + + G +
Sbjct: 710 MRVEFKSDNTVSKRGFRA---HFFSD--KDECAKDNGGCQHECVNTFGSYLCRCRNGYWL 764
Query: 61 ANTIPDSTDTSSNTAVVRVWWGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLT 120
D + + V GT SPN+P+ P R W I++ G ++ LT
Sbjct: 765 HENGHDCKEAGCAHKISSV-------EGTLASPNWPDKYPSRRECTWNISSTAGHRVKLT 817
Query: 121 FSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSR 180
F+ + H C +H+ +++G S +P L + C S + +SG++M + F++D S
Sbjct: 818 FNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTV-ASGSSMFLRFYSDASV 876
Query: 181 PYGGFTASHTSSEDADKVGCCKLCGGSL-PNTPEGNFTSPGYDGVRNYSRNLNCEWTLSN 239
GF A H++ CGG L S G NY C+W +
Sbjct: 877 QRKGFQAVHSTE-----------CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVI-- 923
Query: 240 PNQGNSSIYIHFEDFYLESHQDCQFDVLE 268
+ + + F F +E DC +D +E
Sbjct: 924 VAEDGYGVELTFRTFEVEEEADCGYDYME 952
Score = 70.5 bits (171), Expect = 5e-12
Identities = 73/301 (24%), Positives = 115/301 (38%), Gaps = 52/301 (17%)
Query: 1 MYLRFRSDNSPNHMGFKGLSRHYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYC 60
++++F SD S N GF ++ + + GCE H N LG Y
Sbjct: 554 LWMKFVSDGSINKAGFAA----NFFKEVDECSWPDHGGCE---------HRCVNTLGSYK 600
Query: 61 ANTIPDSTDTSSNTAVVRVWWGSQGSA--GTSTSPNYPNLNPHGRIYEWRITAPEGRQIT 118
P + +++ + V G + GT TSP +P P + W++ AP +I+
Sbjct: 601 CACDP-GYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRIS 659
Query: 119 LTFSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDG 178
L F L + C + V V +G+ ++ + C S I S N M+V F +D
Sbjct: 660 LQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGS-ETPEVITSQSNNMRVEFKSDN 718
Query: 179 SRPYGGFTASHTSSED---ADKVGC---------------------------CKLCG-GS 207
+ GF A S +D D GC CK G
Sbjct: 719 TVSKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSYLCRCRNGYWLHENGHDCKEAGCAH 778
Query: 208 LPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQFDVL 267
++ EG SP + Y C W +S + + + F +F +E HQ+C +D L
Sbjct: 779 KISSVEGTLASPNWPD--KYPSRRECTWNIS--STAGHRVKLTFNEFEIEQHQECAYDHL 834
Query: 268 E 268
E
Sbjct: 835 E 835
Score = 68.6 bits (166), Expect = 2e-11
Identities = 51/199 (25%), Positives = 88/199 (44%), Gaps = 25/199 (12%)
Query: 22 HYLTNSFEDFNLQNSSGCEKDFVEIWDYHTS-GNILGRYCANTIPDSTDTSSNTAVVRVW 80
H + +F +F ++ C D +E++D S ILGR+C + PD T S ++ +R +
Sbjct: 812 HRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFY 871
Query: 81 -----------------WGSQGSAGTSTSPNYP------NLNPHGRIYEWRITAPEGRQI 117
G + A T Y N P +W I A +G +
Sbjct: 872 SDASVQRKGFQAVHSTECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGV 931
Query: 118 TLTFSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTD 177
LTF + C +++ ++G S++P+L + C S EI S+G+++ + F TD
Sbjct: 932 ELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGS-GPLEEIYSAGDSLMIRFRTD 990
Query: 178 GSRPYGGFTASHTSSEDAD 196
+ GF A +TS++ D
Sbjct: 991 DTINKKGFHARYTSTKFQD 1009
Score = 63.5 bits (153), Expect = 6e-10
Identities = 47/187 (25%), Positives = 82/187 (43%), Gaps = 17/187 (9%)
Query: 84 QGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRLATHLSCNSEHVIVFNGI 143
Q + G ++P +PN P WRI+ G +I L F+++ L C ++V V +G
Sbjct: 356 QDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGY 415
Query: 144 RSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKL 203
+P L + C + + S+ + + V F + + GF A++ ++
Sbjct: 416 WRKAPLLGRFCGD-KIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEAT----------- 463
Query: 204 CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
CGG + N G SP Y +Y + C W ++ + + F+ F +E H C
Sbjct: 464 CGGDM-NKDAGQIQSPNYPD--DYRPSKECVWRITVSE--GFHVGLTFQAFEIERHDSCA 518
Query: 264 FDVLEFR 270
+D LE R
Sbjct: 519 YDYLEVR 525
>gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Homo
sapiens]
Length = 986
Score = 94.4 bits (233), Expect = 3e-19
Identities = 67/269 (24%), Positives = 124/269 (46%), Gaps = 27/269 (10%)
Query: 1 MYLRFRSDNSPNHMGFKGLSRHYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYC 60
M + F+SDN+ + GFK H+ ++ +D +++ GC++D V + + G
Sbjct: 681 MRVEFKSDNTVSKKGFKA---HFFSD--KDECSKDNGGCQQDCVNTFGSYECQCRSGFVL 735
Query: 61 ANTIPDSTDTSSNTAVVRVWWGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLT 120
+ D + + V ++GT TSPN+P+ P + W I++ G ++ LT
Sbjct: 736 HDNKHDCKEAGCDHKVT-------STSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLT 788
Query: 121 FSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSR 180
F + + + C +H+ VF+G + +P L + C S + ++G+ M + F++D S
Sbjct: 789 FMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGS-KKPEPVLATGSRMFLRFYSDNSV 847
Query: 181 PYGGFTASHTSSEDADKVGCCKLCGGSL-PNTPEGNFTSPGYDGVRNYSRNLNCEWTLSN 239
GF ASH + CGG + + + S G NY ++CEW +
Sbjct: 848 QRKGFQASHATE-----------CGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVI-- 894
Query: 240 PNQGNSSIYIHFEDFYLESHQDCQFDVLE 268
+ + + F+ F +E DC +D +E
Sbjct: 895 VAEEGYGVELVFQTFEVEEETDCGYDYME 923
Score = 86.3 bits (212), Expect = 9e-17
Identities = 80/296 (27%), Positives = 121/296 (40%), Gaps = 58/296 (19%)
Query: 27 SFEDFNLQNSSGCEKDFVEIWD-YHTSGNILGRYCANTIPD---STDT--------SSNT 74
+F +L S C D+VE+ D + + GR+C + +P+ STD+ SSN
Sbjct: 363 NFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNW 422
Query: 75 ------AVVRVWWGS--QGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRL 126
AV G + G SPNYP+ ++ WRI EG + LTF + +
Sbjct: 423 VGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEI 482
Query: 127 ATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFT 186
H SC +++ V +G +S + + C +IKS+ + + + F +DGS GF
Sbjct: 483 ERHDSCAYDYLEVRDGHSESSTLIGRYC-GYEKPDDIKSTSSRLWLKFVSDGSINKAGFA 541
Query: 187 ASHTSSED--------------------------------ADKVGCCKLCGGSLPNTPEG 214
+ D DK C CGG L G
Sbjct: 542 VNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKL-NG 600
Query: 215 NFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQFDVLEFR 270
+ TSPG+ + Y N NC W L P Q I + F+ F E + C++D +E R
Sbjct: 601 SITSPGWP--KEYPPNKNCIWQLVAPTQ--YRISLQFDFFETEGNDVCKYDFVEVR 652
Score = 62.8 bits (151), Expect = 1e-09
Identities = 47/199 (23%), Positives = 86/199 (43%), Gaps = 25/199 (12%)
Query: 22 HYLTNSFEDFNLQNSSGCEKDFVEIWDYHTS-GNILGRYCANTIPDSTDTSSNTAVVRVW 80
H + +F + ++++ C D +E++D + +LGR+C + P+ + + +R +
Sbjct: 783 HRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFY 842
Query: 81 -----------------WGSQGSAGTSTSPNYP------NLNPHGRIYEWRITAPEGRQI 117
G Q A T Y N P G EW I A EG +
Sbjct: 843 SDNSVQRKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGV 902
Query: 118 TLTFSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTD 177
L F + C +++ +F+G S +P+L + C S E+ S+G+++ V F +D
Sbjct: 903 ELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGS-GPPEEVYSAGDSVLVKFHSD 961
Query: 178 GSRPYGGFTASHTSSEDAD 196
+ GF +TS++ D
Sbjct: 962 DTITKKGFHLRYTSTKFQD 980
Score = 61.6 bits (148), Expect = 2e-09
Identities = 56/209 (26%), Positives = 88/209 (42%), Gaps = 21/209 (10%)
Query: 84 QGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRLATHLSCNSEHVIVFNGI 143
Q S G +SP YPN WRI+ G +I L F++L L C ++V V +G
Sbjct: 327 QDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGF 386
Query: 144 RSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKL 203
+P + C S + I S+ + + V F + + GF A + + +
Sbjct: 387 WRKAPLRGRFCGS-KLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA-----------I 434
Query: 204 CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
CGG + G+ SP Y +Y + C W + + + F+ F +E H C
Sbjct: 435 CGGDVKKD-YGHIQSPNYPD--DYRPSKVCIWRIQVSE--GFHVGLTFQSFEIERHDSCA 489
Query: 264 FDVLEFRVVASEHWKVPFSLISRLSGWSE 292
+D LE R SE +LI R G+ +
Sbjct: 490 YDYLEVRDGHSE----SSTLIGRYCGYEK 514
Score = 58.5 bits (140), Expect = 2e-08
Identities = 73/303 (24%), Positives = 109/303 (35%), Gaps = 56/303 (18%)
Query: 1 MYLRFRSDNSPNHMGFKGLSRHYLTNSFEDFN---LQNSSGCEKDFVEIWDYHTSGNILG 57
++L+F SD S N GF N F++ + N GCE+ + N LG
Sbjct: 525 LWLKFVSDGSINKAGFA-------VNFFKEVDECSRPNRGGCEQRCL---------NTLG 568
Query: 58 RYCANTIPDSTDTSSNTAVVRVWWGSQGSA-GTSTSPNYPNLNPHGRIYEWRITAPEGRQ 116
Y + P G G+ TSP +P P + W++ AP +
Sbjct: 569 SYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYR 628
Query: 117 ITLTFSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFT 176
I+L F + C + V V +G+ ++S K C S I S N M+V F +
Sbjct: 629 ISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGS-EKPEVITSQYNNMRVEFKS 687
Query: 177 DGSRPYGGFTASHTSSED---ADKVGC---------------------------CKLCG- 205
D + GF A S +D D GC CK G
Sbjct: 688 DNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGC 747
Query: 206 GSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQFD 265
+ G TSP + Y C W +S + + + F + +ES +C +D
Sbjct: 748 DHKVTSTSGTITSPNWPD--KYPSKKECTWAIS--STPGHRVKLTFMEMDIESQPECAYD 803
Query: 266 VLE 268
LE
Sbjct: 804 HLE 806
>gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Homo
sapiens]
Length = 730
Score = 86.3 bits (212), Expect = 9e-17
Identities = 80/296 (27%), Positives = 121/296 (40%), Gaps = 58/296 (19%)
Query: 27 SFEDFNLQNSSGCEKDFVEIWD-YHTSGNILGRYCANTIPD---STDT--------SSNT 74
+F +L S C D+VE+ D + + GR+C + +P+ STD+ SSN
Sbjct: 363 NFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNW 422
Query: 75 ------AVVRVWWGS--QGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRL 126
AV G + G SPNYP+ ++ WRI EG + LTF + +
Sbjct: 423 VGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEI 482
Query: 127 ATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFT 186
H SC +++ V +G +S + + C +IKS+ + + + F +DGS GF
Sbjct: 483 ERHDSCAYDYLEVRDGHSESSTLIGRYC-GYEKPDDIKSTSSRLWLKFVSDGSINKAGFA 541
Query: 187 ASHTSSED--------------------------------ADKVGCCKLCGGSLPNTPEG 214
+ D DK C CGG L G
Sbjct: 542 VNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKL-NG 600
Query: 215 NFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQFDVLEFR 270
+ TSPG+ + Y N NC W L P Q I + F+ F E + C++D +E R
Sbjct: 601 SITSPGWP--KEYPPNKNCIWQLVAPTQ--YRISLQFDFFETEGNDVCKYDFVEVR 652
Score = 61.6 bits (148), Expect = 2e-09
Identities = 56/209 (26%), Positives = 88/209 (42%), Gaps = 21/209 (10%)
Query: 84 QGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRLATHLSCNSEHVIVFNGI 143
Q S G +SP YPN WRI+ G +I L F++L L C ++V V +G
Sbjct: 327 QDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGF 386
Query: 144 RSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKL 203
+P + C S + I S+ + + V F + + GF A + + +
Sbjct: 387 WRKAPLRGRFCGS-KLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA-----------I 434
Query: 204 CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
CGG + G+ SP Y +Y + C W + + + F+ F +E H C
Sbjct: 435 CGGDVKKD-YGHIQSPNYPD--DYRPSKVCIWRIQVSE--GFHVGLTFQSFEIERHDSCA 489
Query: 264 FDVLEFRVVASEHWKVPFSLISRLSGWSE 292
+D LE R SE +LI R G+ +
Sbjct: 490 YDYLEVRDGHSE----SSTLIGRYCGYEK 514
Score = 47.4 bits (111), Expect = 4e-05
Identities = 53/197 (26%), Positives = 78/197 (39%), Gaps = 22/197 (11%)
Query: 1 MYLRFRSDNSPNHMGFKGLSRHYLTNSFEDFN---LQNSSGCEKDFVEIWDYHTSGNILG 57
++L+F SD S N GF N F++ + N GCE+ + N LG
Sbjct: 525 LWLKFVSDGSINKAGFA-------VNFFKEVDECSRPNRGGCEQRCL---------NTLG 568
Query: 58 RYCANTIPDSTDTSSNTAVVRVWWGSQGSA-GTSTSPNYPNLNPHGRIYEWRITAPEGRQ 116
Y + P G G+ TSP +P P + W++ AP +
Sbjct: 569 SYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYR 628
Query: 117 ITLTFSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFT 176
I+L F + C + V V +G+ ++S K C S I S N M+V F +
Sbjct: 629 ISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGS-EKPEVITSQYNNMRVEFKS 687
Query: 177 DGSRPYGGFTASHTSSE 193
D + GF A H SE
Sbjct: 688 DNTVSKKGFKA-HFFSE 703
>gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Homo
sapiens]
Length = 823
Score = 86.3 bits (212), Expect = 9e-17
Identities = 80/296 (27%), Positives = 121/296 (40%), Gaps = 58/296 (19%)
Query: 27 SFEDFNLQNSSGCEKDFVEIWD-YHTSGNILGRYCANTIPD---STDT--------SSNT 74
+F +L S C D+VE+ D + + GR+C + +P+ STD+ SSN
Sbjct: 363 NFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNW 422
Query: 75 ------AVVRVWWGS--QGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRL 126
AV G + G SPNYP+ ++ WRI EG + LTF + +
Sbjct: 423 VGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEI 482
Query: 127 ATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFT 186
H SC +++ V +G +S + + C +IKS+ + + + F +DGS GF
Sbjct: 483 ERHDSCAYDYLEVRDGHSESSTLIGRYC-GYEKPDDIKSTSSRLWLKFVSDGSINKAGFA 541
Query: 187 ASHTSSED--------------------------------ADKVGCCKLCGGSLPNTPEG 214
+ D DK C CGG L G
Sbjct: 542 VNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKL-NG 600
Query: 215 NFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQFDVLEFR 270
+ TSPG+ + Y N NC W L P Q I + F+ F E + C++D +E R
Sbjct: 601 SITSPGWP--KEYPPNKNCIWQLVAPTQ--YRISLQFDFFETEGNDVCKYDFVEVR 652
Score = 61.6 bits (148), Expect = 2e-09
Identities = 56/209 (26%), Positives = 88/209 (42%), Gaps = 21/209 (10%)
Query: 84 QGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRLATHLSCNSEHVIVFNGI 143
Q S G +SP YPN WRI+ G +I L F++L L C ++V V +G
Sbjct: 327 QDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGF 386
Query: 144 RSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKL 203
+P + C S + I S+ + + V F + + GF A + + +
Sbjct: 387 WRKAPLRGRFCGS-KLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA-----------I 434
Query: 204 CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
CGG + G+ SP Y +Y + C W + + + F+ F +E H C
Sbjct: 435 CGGDVKKD-YGHIQSPNYPD--DYRPSKVCIWRIQVSE--GFHVGLTFQSFEIERHDSCA 489
Query: 264 FDVLEFRVVASEHWKVPFSLISRLSGWSE 292
+D LE R SE +LI R G+ +
Sbjct: 490 YDYLEVRDGHSE----SSTLIGRYCGYEK 514
Score = 47.0 bits (110), Expect = 6e-05
Identities = 50/191 (26%), Positives = 75/191 (39%), Gaps = 21/191 (10%)
Query: 1 MYLRFRSDNSPNHMGFKGLSRHYLTNSFEDFN---LQNSSGCEKDFVEIWDYHTSGNILG 57
++L+F SD S N GF N F++ + N GCE+ + N LG
Sbjct: 525 LWLKFVSDGSINKAGFA-------VNFFKEVDECSRPNRGGCEQRCL---------NTLG 568
Query: 58 RYCANTIPDSTDTSSNTAVVRVWWGSQGSA-GTSTSPNYPNLNPHGRIYEWRITAPEGRQ 116
Y + P G G+ TSP +P P + W++ AP +
Sbjct: 569 SYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYR 628
Query: 117 ITLTFSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFT 176
I+L F + C + V V +G+ ++S K C S I S N M+V F +
Sbjct: 629 ISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGS-EKPEVITSQYNNMRVEFKS 687
Query: 177 DGSRPYGGFTA 187
D + GF A
Sbjct: 688 DNTVSKKGFKA 698
>gi|7019483 procollagen C-endopeptidase enhancer 2 [Homo sapiens]
Length = 415
Score = 82.8 bits (203), Expect = 9e-16
Identities = 53/181 (29%), Positives = 89/181 (49%), Gaps = 8/181 (4%)
Query: 85 GSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRLATHLSCNSEHVIVFNGIR 144
G +G S +P + P W+IT PEG+ + L F + L + C + V V+NG
Sbjct: 39 GESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCRYDFVDVYNG-H 97
Query: 145 SNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKLC 204
+N ++ + C + + + SSGN M V +D + GF A +++E ++ + C
Sbjct: 98 ANGQRIGRFCGTFRPGA-LVSSGNKMMVQMISDANTAGNGFMAMFSAAEPNERGD--QYC 154
Query: 205 GGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQF 264
GG L + P G+F +P + R+Y + C W + P N I + FE F +E C++
Sbjct: 155 GGLL-DRPSGSFKTPNWPD-RDYPAGVTCVWHIVAPK--NQLIELKFEKFDVERDNYCRY 210
Query: 265 D 265
D
Sbjct: 211 D 211
Score = 58.9 bits (141), Expect = 1e-08
Identities = 45/189 (23%), Positives = 83/189 (43%), Gaps = 31/189 (16%)
Query: 27 SFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYCANTIPDSTDTSSNTAVVRVWWGSQGS 86
+F +L++ + C DFV++++ H +G +GR+C P + +S N +V++ + +
Sbjct: 74 NFRFIDLESDNLCRYDFVDVYNGHANGQRIGRFCGTFRPGALVSSGNKMMVQMISDANTA 133
Query: 87 ----------------------------AGTSTSPNYPNLN-PHGRIYEWRITAPEGRQI 117
+G+ +PN+P+ + P G W I AP+ + I
Sbjct: 134 GNGFMAMFSAAEPNERGDQYCGGLLDRPSGSFKTPNWPDRDYPAGVTCVWHIVAPKNQLI 193
Query: 118 TLTFSNLRLATHLSCNSEHVIVFNGIRSN-SPQLEKLCSSVNVSSEIKSSGNTMKVIFFT 176
L F + C ++V VFNG N + ++ K C + + I S N + + F +
Sbjct: 194 ELKFEKFDVERDNYCRYDYVAVFNGGEVNDARRIGKYCGD-SPPAPIVSERNELLIQFLS 252
Query: 177 DGSRPYGGF 185
D S GF
Sbjct: 253 DLSLTADGF 261
>gi|72384339 CUB domain containing protein 2 [Homo sapiens]
Length = 449
Score = 78.2 bits (191), Expect = 2e-14
Identities = 52/180 (28%), Positives = 81/180 (45%), Gaps = 17/180 (9%)
Query: 87 AGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRLATHLSCNSEHVIVFNGIRSN 146
+G +SPN+P L P+ W I EG + LTF L H +C+ + + ++NG +
Sbjct: 38 SGNFSSPNFPRLYPYNTECSWLIVVAEGSSVLLTFHAFDLEYHDTCSFDFLEIYNGASPD 97
Query: 147 SPQ-LEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKLCG 205
L + C V SS + M VIF +D GF+A + +CG
Sbjct: 98 KGNLLGRFCGKV-PPPPFTSSWHVMSVIFHSDKHVASHGFSAGYQKD----------VCG 146
Query: 206 GSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQFD 265
G L G TSP Y NY ++ C W + G + + + F DF +E +++C +D
Sbjct: 147 GVLTGL-SGVLTSPEYP--NNYPNSMECHWVIR--AAGPAHVKLVFVDFQVEGNEECTYD 201
Score = 72.8 bits (177), Expect = 1e-12
Identities = 72/276 (26%), Positives = 114/276 (41%), Gaps = 46/276 (16%)
Query: 27 SFEDFNLQNSSGCEKDFVEIWDYHT--SGNILGRYCANTIPDSTDTSSNTAVVRVWWGSQ 84
+F F+L+ C DF+EI++ + GN+LGR+C +P TSS + ++ +
Sbjct: 71 TFHAFDLEYHDTCSFDFLEIYNGASPDKGNLLGRFCGK-VPPPPFTSSWHVMSVIFHSDK 129
Query: 85 ---------------------GSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSN 123
G +G TSP YPN P+ W I A + L F +
Sbjct: 130 HVASHGFSAGYQKDVCGGVLTGLSGVLTSPEYPNNYPNSMECHWVIRAAGPAHVKLVFVD 189
Query: 124 LRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYG 183
++ + C ++V V G + C S + + S G+ ++V+F +D +
Sbjct: 190 FQVEGNEECTYDYVAVLGG--PGPTRGHHYCGSTRPPT-LVSLGHELQVVFKSDFNIGGR 246
Query: 184 GFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQG 243
GF A + S E C+ + GNF+SP Y +Y N+ C WT+ P
Sbjct: 247 GFKAYYFSGE-------CQ----EVYMAMRGNFSSPQYPS--SYPNNIRCHWTIRLP--P 291
Query: 244 NSSIYIHFEDFYLES----HQDCQFDVLEFRVVASE 275
+ + F D LE + C FD L ASE
Sbjct: 292 GYQVKVFFLDLDLEEPNSLTKTCDFDHLAAFDGASE 327
Score = 51.2 bits (121), Expect = 3e-06
Identities = 55/242 (22%), Positives = 94/242 (38%), Gaps = 43/242 (17%)
Query: 8 DNSPN----HMGFKGLSRHYLTNSFEDFNLQNSSGCEKDFVEIWDYH--TSGNILGRYCA 61
+N PN H + ++ F DF ++ + C D+V + T G+ YC
Sbjct: 163 NNYPNSMECHWVIRAAGPAHVKLVFVDFQVEGNEECTYDYVAVLGGPGPTRGH---HYCG 219
Query: 62 NTIPDS-------------TDTSSNTAVVRVWWGS-------QGSAGTSTSPNYPNLNPH 101
+T P + +D + + ++ S G +SP YP+ P+
Sbjct: 220 STRPPTLVSLGHELQVVFKSDFNIGGRGFKAYYFSGECQEVYMAMRGNFSSPQYPSSYPN 279
Query: 102 GRIYEWRITAPEGRQITLTFSNLRLATHLS----CNSEHVIVFNGIRSNSPQLEKLCSSV 157
W I P G Q+ + F +L L S C+ +H+ F+G +P L C
Sbjct: 280 NIRCHWTIRLPPGYQVKVFFLDLDLEEPNSLTKTCDFDHLAAFDGASEEAPLLGNWCGH- 338
Query: 158 NVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFT 217
++ + SS N + ++ TD S GF+ ++ + +GC GS EG
Sbjct: 339 HLPPPVTSSHNQLLLLLHTDRSTTRRGFSVAYIGGQ----LGC-----GSGSTEGEGEAL 389
Query: 218 SP 219
P
Sbjct: 390 QP 391
Score = 47.4 bits (111), Expect = 4e-05
Identities = 27/65 (41%), Positives = 33/65 (50%), Gaps = 5/65 (7%)
Query: 204 CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
CGG L + P GNF+SP + R Y N C W + SS+ + F F LE H C
Sbjct: 30 CGGVL-SAPSGNFSSPNFP--RLYPYNTECSWLIVVAE--GSSVLLTFHAFDLEYHDTCS 84
Query: 264 FDVLE 268
FD LE
Sbjct: 85 FDFLE 89
>gi|157653329 procollagen C-endopeptidase enhancer [Homo sapiens]
Length = 449
Score = 73.2 bits (178), Expect = 7e-13
Identities = 58/194 (29%), Positives = 82/194 (42%), Gaps = 32/194 (16%)
Query: 27 SFEDFNLQNSSGCEKDFVEIW-DYHTSGNILGRYCANTIPDSTDTSSNTAVVRV------ 79
SF F+L+ C D +E++ TSG LGR+C P N +R+
Sbjct: 78 SFRVFDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGT 137
Query: 80 -------WWGSQGSAGTS---------------TSPNYPNLN-PHGRIYEWRITAPEGRQ 116
W+ + ++GT T+PN+P + P G W I AP +
Sbjct: 138 GGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQV 197
Query: 117 ITLTFSNLRLATHLSCNSEHVIVFNG-IRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFF 175
I LTF L C + V VFNG + +S +L K C V I S GN + V F
Sbjct: 198 IALTFEKFDLEPDTYCRYDSVSVFNGAVSDDSRRLGKFCGDA-VPGSISSEGNELLVQFV 256
Query: 176 TDGSRPYGGFTASH 189
+D S GF+AS+
Sbjct: 257 SDLSVTADGFSASY 270
Score = 69.7 bits (169), Expect = 8e-12
Identities = 48/182 (26%), Positives = 84/182 (46%), Gaps = 7/182 (3%)
Query: 84 QGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRLATHLSCNSEHVIVFNGI 143
+G +G S +PNL P + W IT PEG+ ++L+F L H +C + + VF G
Sbjct: 42 KGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLELHPACRYDALEVFAGS 101
Query: 144 RSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKL 203
++ +L + C + + + + GN + + TD GF ++ + +
Sbjct: 102 GTSGQRLGRFCGTFR-PAPLVAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEH--QF 158
Query: 204 CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
CGG L +G T+P + +Y ++C W + P + I + FE F LE C+
Sbjct: 159 CGGRLEKA-QGTLTTPNWP-ESDYPPGISCSWHIIAP--PDQVIALTFEKFDLEPDTYCR 214
Query: 264 FD 265
+D
Sbjct: 215 YD 216
Score = 38.1 bits (87), Expect = 0.027
Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 5/66 (7%)
Query: 203 LCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDC 262
LCGG + G S G+ + Y N C WT++ P ++ + F F LE H C
Sbjct: 36 LCGGDVKGE-SGYVASEGFPNL--YPPNKECIWTITVPE--GQTVSLSFRVFDLELHPAC 90
Query: 263 QFDVLE 268
++D LE
Sbjct: 91 RYDALE 96
>gi|30520377 CUB and zona pellucida-like domains 1 [Homo sapiens]
Length = 607
Score = 72.4 bits (176), Expect = 1e-12
Identities = 51/167 (30%), Positives = 83/167 (49%), Gaps = 20/167 (11%)
Query: 107 WRITAPEGRQITLTFSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSS 166
W I PE + I + FS ++L SC SE++ VF+G SN P L ++CS + +SS
Sbjct: 60 WTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFESS 119
Query: 167 GNTMKVIFFTDGSR------PYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPG 220
+T+ TD +R + F + + S + CGG L +T EG+FTSP
Sbjct: 120 SSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPN---------CGGYL-DTLEGSFTSPN 169
Query: 221 YDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQFDVL 267
Y + + C W + + + I ++F++ +LE + C+FD L
Sbjct: 170 YP--KPHPELAYCVWHIQ--VEKDYKIKLNFKEIFLEIDKQCKFDFL 212
Score = 64.7 bits (156), Expect = 3e-10
Identities = 49/193 (25%), Positives = 84/193 (43%), Gaps = 31/193 (16%)
Query: 28 FEDFNLQNSSGCEKDFVEIWDYHTS-GNILGRYCA-NTIPDSTDTSSNTAVVRVWWGS-- 83
F L CE + ++++D +S G +LG+ C+ N ++SS+T ++ S
Sbjct: 74 FSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFESSSSTLTFQIVTDSAR 133
Query: 84 -------------------------QGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQIT 118
G+ TSPNYP +P W I + +I
Sbjct: 134 IQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIK 193
Query: 119 LTFSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDG 178
L F + L C + + +++G +NS + ++C V + E SS N++ V+ TD
Sbjct: 194 LNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTPTFE--SSSNSLTVVLSTDY 251
Query: 179 SRPYGGFTASHTS 191
+ Y GF+AS+TS
Sbjct: 252 ANSYRGFSASYTS 264
Score = 29.6 bits (65), Expect = 9.4
Identities = 45/175 (25%), Positives = 72/175 (41%), Gaps = 29/175 (16%)
Query: 27 SFEDFNLQNSSGCEKDFVEIWD-YHTSGNILGRYCANTIPDSTDTSSNTAVVRVWWGSQG 85
+F++ L+ C+ DF+ I+D T+ ++G+ C P +S++ VV +
Sbjct: 195 NFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTPTFESSSNSLTVVLSTDYANS 254
Query: 86 SAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRLATHLSCNSEHVIVFNGIRS 145
G S S + IY I +LT S+ R+ +S ++ FN
Sbjct: 255 YRGFSAS--------YTSIYAENINT-----TSLTCSSDRMRVIIS--KSYLEAFNS-NG 298
Query: 146 NSPQLE------KLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGG---FTASHTS 191
N+ QL+ KL + V S + G KV D S Y F+AS TS
Sbjct: 299 NNLQLKDPTCRPKLSNVVEFSVPLNGCGTIRKV---EDQSITYTNIITFSASSTS 350
>gi|239756223 PREDICTED: ankyrin repeat domain-containing protein
ENSP00000383090-like [Homo sapiens]
Length = 270
Score = 67.8 bits (164), Expect = 3e-11
Identities = 31/42 (73%), Positives = 35/42 (83%)
Query: 522 LSQSHATEQPEGTSEGTPDEAAPLAERTPDMAESLVEKPPDE 563
+S++ PEGTSEGTPDEAAPL ERTPDMAESLVE+ PDE
Sbjct: 229 ISKNSQNSNPEGTSEGTPDEAAPLVERTPDMAESLVERTPDE 270
>gi|169209369 PREDICTED: similar to Putative ankyrin repeat
domain-containing protein ENSP00000383090 [Homo sapiens]
Length = 193
Score = 67.8 bits (164), Expect = 3e-11
Identities = 31/42 (73%), Positives = 35/42 (83%)
Query: 522 LSQSHATEQPEGTSEGTPDEAAPLAERTPDMAESLVEKPPDE 563
+S++ PEGTSEGTPDEAAPL ERTPDMAESLVE+ PDE
Sbjct: 152 ISKNSQNSNPEGTSEGTPDEAAPLVERTPDMAESLVERTPDE 193
>gi|239745040 PREDICTED: ankyrin repeat domain-containing protein
ENSP00000383090-like [Homo sapiens]
Length = 270
Score = 67.8 bits (164), Expect = 3e-11
Identities = 31/42 (73%), Positives = 35/42 (83%)
Query: 522 LSQSHATEQPEGTSEGTPDEAAPLAERTPDMAESLVEKPPDE 563
+S++ PEGTSEGTPDEAAPL ERTPDMAESLVE+ PDE
Sbjct: 229 ISKNSQNSNPEGTSEGTPDEAAPLVERTPDMAESLVERTPDE 270
>gi|20373181 neuropilin- and tolloid-like protein 1 isoform 3
precursor [Homo sapiens]
Length = 533
Score = 67.4 bits (163), Expect = 4e-11
Identities = 53/195 (27%), Positives = 82/195 (42%), Gaps = 20/195 (10%)
Query: 81 WGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSN-LRLATHLSCNSEHVIV 139
W G TSPNYP+ P R + I A + I L F + C +H+ V
Sbjct: 44 WTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEV 103
Query: 140 FNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVG 199
+G SP + + C N IKSSG + + FF DG GF+A + + D D
Sbjct: 104 RDGPFGFSPIIGRFCGQQN-PPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKD 162
Query: 200 CCKLCGGSLPNTPEGNFTSPGYDGV-----------RNYSRNLNCEWTLSNPNQGNSSIY 248
G+L P F G +G+ S ++C+W + P + S IY
Sbjct: 163 L-----GALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPR--SKIY 215
Query: 249 IHFEDFYLESHQDCQ 263
+ F D+ +++ +C+
Sbjct: 216 LRFLDYEMQNSNECK 230
Score = 35.8 bits (81), Expect = 0.13
Identities = 15/53 (28%), Positives = 30/53 (56%)
Query: 28 FEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYCANTIPDSTDTSSNTAVVRVW 80
F D+ +QNS+ C+++FV ++D +S L +T+ + + V+R+W
Sbjct: 218 FLDYEMQNSNECKRNFVAVYDGSSSVEDLKAKFCSTVANDVMLRTGLGVIRMW 270
Score = 30.4 bits (67), Expect = 5.5
Identities = 29/101 (28%), Positives = 45/101 (44%), Gaps = 13/101 (12%)
Query: 172 VIFFTDGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNL 231
+I G+ G T T+SE V C G + G FTSP Y Y +
Sbjct: 15 IILHLSGATKKG--TEKQTTSETQKSVQC----GTWTKHAEGGIFTSPNYPS--KYPPDR 66
Query: 232 NCEWTL-SNPNQGNSSIYIHFEDFY-LESHQDCQFDVLEFR 270
C + + + P Q I ++F++ Y +E +C+FD +E R
Sbjct: 67 ECIYIIEAAPRQ---CIELYFDEKYSIEPSWECKFDHIEVR 104
>gi|23510396 neuropilin- and tolloid-like protein 1 isoform 2
precursor [Homo sapiens]
Length = 532
Score = 67.4 bits (163), Expect = 4e-11
Identities = 53/195 (27%), Positives = 82/195 (42%), Gaps = 20/195 (10%)
Query: 81 WGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSN-LRLATHLSCNSEHVIV 139
W G TSPNYP+ P R + I A + I L F + C +H+ V
Sbjct: 43 WTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEV 102
Query: 140 FNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVG 199
+G SP + + C N IKSSG + + FF DG GF+A + + D D
Sbjct: 103 RDGPFGFSPIIGRFCGQQN-PPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKD 161
Query: 200 CCKLCGGSLPNTPEGNFTSPGYDGV-----------RNYSRNLNCEWTLSNPNQGNSSIY 248
G+L P F G +G+ S ++C+W + P + S IY
Sbjct: 162 L-----GALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPR--SKIY 214
Query: 249 IHFEDFYLESHQDCQ 263
+ F D+ +++ +C+
Sbjct: 215 LRFLDYEMQNSNECK 229
Score = 35.8 bits (81), Expect = 0.13
Identities = 15/53 (28%), Positives = 30/53 (56%)
Query: 28 FEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYCANTIPDSTDTSSNTAVVRVW 80
F D+ +QNS+ C+++FV ++D +S L +T+ + + V+R+W
Sbjct: 217 FLDYEMQNSNECKRNFVAVYDGSSSVEDLKAKFCSTVANDVMLRTGLGVIRMW 269
Score = 30.4 bits (67), Expect = 5.5
Identities = 29/101 (28%), Positives = 45/101 (44%), Gaps = 13/101 (12%)
Query: 172 VIFFTDGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNL 231
+I G+ G T T+SE V C G + G FTSP Y Y +
Sbjct: 14 IILHLSGATKKG--TEKQTTSETQKSVQC----GTWTKHAEGGIFTSPNYPS--KYPPDR 65
Query: 232 NCEWTL-SNPNQGNSSIYIHFEDFY-LESHQDCQFDVLEFR 270
C + + + P Q I ++F++ Y +E +C+FD +E R
Sbjct: 66 ECIYIIEAAPRQ---CIELYFDEKYSIEPSWECKFDHIEVR 103
>gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens]
Length = 1662
Score = 62.4 bits (150), Expect = 1e-09
Identities = 49/155 (31%), Positives = 74/155 (47%), Gaps = 12/155 (7%)
Query: 47 WDYHTSGNI--LGRYCANTIPDSTDTS----SNTAVVRVWWGSQG----SAGTSTSPNYP 96
W H G+ G C+ T +ST T + T R G ++GT +SP+YP
Sbjct: 973 WLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYP 1032
Query: 97 NLNPHGRIYEWRITAPEGRQITLTFSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSS 156
P+ W I G +I L FSNL+L H +C+ ++V +F+G ++S L K+C+
Sbjct: 1033 AYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICN- 1091
Query: 157 VNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTS 191
+ SS N M + F +D S GF A + S
Sbjct: 1092 -DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1125
Score = 53.5 bits (127), Expect = 6e-07
Identities = 46/154 (29%), Positives = 68/154 (44%), Gaps = 10/154 (6%)
Query: 57 GRYCANTIPDSTDTSSNTAVVRVWWGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQ 116
G + + P T NT + SQ S G +SP YP P+ W I +
Sbjct: 1236 GNHLSTPAPFLNITRPNTDYSCGGFLSQPS-GDFSSPFYPGNYPNNAKCVWDIEVQNNYR 1294
Query: 117 ITLTFSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFT 176
+T+ F +++L CN +++ VF+G +SP + ++C S SS N M + F +
Sbjct: 1295 VTVIFRDVQLEG--GCNYDYIEVFDGPYRSSPLIARVCDGARGS--FTSSSNFMSIRFIS 1350
Query: 177 DGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPN 210
D S GF A + SS D LC LPN
Sbjct: 1351 DHSITRRGFRAEYYSSPSNDSTNL--LC---LPN 1379
Score = 42.0 bits (97), Expect = 0.002
Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 7/65 (10%)
Query: 204 CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
CGG L + P G+F+SP Y G NY N C W + Q N + + F D LE C
Sbjct: 1257 CGGFL-SQPSGDFSSPFYPG--NYPNNAKCVWDIE--VQNNYRVTVIFRDVQLEG--GCN 1309
Query: 264 FDVLE 268
+D +E
Sbjct: 1310 YDYIE 1314
Score = 37.7 bits (86), Expect = 0.035
Identities = 24/65 (36%), Positives = 31/65 (47%), Gaps = 5/65 (7%)
Query: 204 CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
CGG L G F+SP Y Y N C W + N G I + F + LE+H +C
Sbjct: 1015 CGGFLFYA-SGTFSSPSYPAY--YPNNAKCVWEIE-VNSGYR-INLGFSNLKLEAHHNCS 1069
Query: 264 FDVLE 268
FD +E
Sbjct: 1070 FDYVE 1074
>gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens]
Length = 1788
Score = 62.4 bits (150), Expect = 1e-09
Identities = 49/155 (31%), Positives = 74/155 (47%), Gaps = 12/155 (7%)
Query: 47 WDYHTSGNI--LGRYCANTIPDSTDTS----SNTAVVRVWWGSQG----SAGTSTSPNYP 96
W H G+ G C+ T +ST T + T R G ++GT +SP+YP
Sbjct: 1099 WLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYP 1158
Query: 97 NLNPHGRIYEWRITAPEGRQITLTFSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSS 156
P+ W I G +I L FSNL+L H +C+ ++V +F+G ++S L K+C+
Sbjct: 1159 AYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICN- 1217
Query: 157 VNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTS 191
+ SS N M + F +D S GF A + S
Sbjct: 1218 -DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1251
Score = 53.5 bits (127), Expect = 6e-07
Identities = 46/154 (29%), Positives = 68/154 (44%), Gaps = 10/154 (6%)
Query: 57 GRYCANTIPDSTDTSSNTAVVRVWWGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQ 116
G + + P T NT + SQ S G +SP YP P+ W I +
Sbjct: 1362 GNHLSTPAPFLNITRPNTDYSCGGFLSQPS-GDFSSPFYPGNYPNNAKCVWDIEVQNNYR 1420
Query: 117 ITLTFSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFT 176
+T+ F +++L CN +++ VF+G +SP + ++C S SS N M + F +
Sbjct: 1421 VTVIFRDVQLEG--GCNYDYIEVFDGPYRSSPLIARVCDGARGS--FTSSSNFMSIRFIS 1476
Query: 177 DGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPN 210
D S GF A + SS D LC LPN
Sbjct: 1477 DHSITRRGFRAEYYSSPSNDSTNL--LC---LPN 1505
Score = 42.0 bits (97), Expect = 0.002
Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 7/65 (10%)
Query: 204 CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
CGG L + P G+F+SP Y G NY N C W + Q N + + F D LE C
Sbjct: 1383 CGGFL-SQPSGDFSSPFYPG--NYPNNAKCVWDIE--VQNNYRVTVIFRDVQLEG--GCN 1435
Query: 264 FDVLE 268
+D +E
Sbjct: 1436 YDYIE 1440
Score = 37.7 bits (86), Expect = 0.035
Identities = 24/65 (36%), Positives = 31/65 (47%), Gaps = 5/65 (7%)
Query: 204 CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
CGG L G F+SP Y Y N C W + N G I + F + LE+H +C
Sbjct: 1141 CGGFLFYA-SGTFSSPSYPAY--YPNNAKCVWEIE-VNSGYR-INLGFSNLKLEAHHNCS 1195
Query: 264 FDVLE 268
FD +E
Sbjct: 1196 FDYVE 1200
>gi|148539844 deleted in malignant brain tumors 1 isoform c precursor
[Homo sapiens]
Length = 2403
Score = 62.4 bits (150), Expect = 1e-09
Identities = 49/155 (31%), Positives = 74/155 (47%), Gaps = 12/155 (7%)
Query: 47 WDYHTSGNI--LGRYCANTIPDSTDTS----SNTAVVRVWWGSQG----SAGTSTSPNYP 96
W H G+ G C+ T +ST T + T R G ++GT +SP+YP
Sbjct: 1714 WLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYP 1773
Query: 97 NLNPHGRIYEWRITAPEGRQITLTFSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSS 156
P+ W I G +I L FSNL+L H +C+ ++V +F+G ++S L K+C+
Sbjct: 1774 AYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICN- 1832
Query: 157 VNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTS 191
+ SS N M + F +D S GF A + S
Sbjct: 1833 -DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1866
Score = 53.5 bits (127), Expect = 6e-07
Identities = 46/154 (29%), Positives = 68/154 (44%), Gaps = 10/154 (6%)
Query: 57 GRYCANTIPDSTDTSSNTAVVRVWWGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQ 116
G + + P T NT + SQ S G +SP YP P+ W I +
Sbjct: 1977 GNHLSTPAPFLNITRPNTDYSCGGFLSQPS-GDFSSPFYPGNYPNNAKCVWDIEVQNNYR 2035
Query: 117 ITLTFSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFT 176
+T+ F +++L CN +++ VF+G +SP + ++C S SS N M + F +
Sbjct: 2036 VTVIFRDVQLEG--GCNYDYIEVFDGPYRSSPLIARVCDGARGS--FTSSSNFMSIRFIS 2091
Query: 177 DGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPN 210
D S GF A + SS D LC LPN
Sbjct: 2092 DHSITRRGFRAEYYSSPSNDSTNL--LC---LPN 2120
Score = 42.0 bits (97), Expect = 0.002
Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 7/65 (10%)
Query: 204 CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
CGG L + P G+F+SP Y G NY N C W + Q N + + F D LE C
Sbjct: 1998 CGGFL-SQPSGDFSSPFYPG--NYPNNAKCVWDIE--VQNNYRVTVIFRDVQLEG--GCN 2050
Query: 264 FDVLE 268
+D +E
Sbjct: 2051 YDYIE 2055
Score = 37.7 bits (86), Expect = 0.035
Identities = 24/65 (36%), Positives = 31/65 (47%), Gaps = 5/65 (7%)
Query: 204 CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
CGG L G F+SP Y Y N C W + N G I + F + LE+H +C
Sbjct: 1756 CGGFLFYA-SGTFSSPSYPAY--YPNNAKCVWEIE-VNSGYR-INLGFSNLKLEAHHNCS 1810
Query: 264 FDVLE 268
FD +E
Sbjct: 1811 FDYVE 1815
>gi|148539842 deleted in malignant brain tumors 1 isoform b precursor
[Homo sapiens]
Length = 2413
Score = 62.4 bits (150), Expect = 1e-09
Identities = 49/155 (31%), Positives = 74/155 (47%), Gaps = 12/155 (7%)
Query: 47 WDYHTSGNI--LGRYCANTIPDSTDTS----SNTAVVRVWWGSQG----SAGTSTSPNYP 96
W H G+ G C+ T +ST T + T R G ++GT +SP+YP
Sbjct: 1724 WLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYP 1783
Query: 97 NLNPHGRIYEWRITAPEGRQITLTFSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSS 156
P+ W I G +I L FSNL+L H +C+ ++V +F+G ++S L K+C+
Sbjct: 1784 AYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICN- 1842
Query: 157 VNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTS 191
+ SS N M + F +D S GF A + S
Sbjct: 1843 -DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1876
Score = 53.5 bits (127), Expect = 6e-07
Identities = 46/154 (29%), Positives = 68/154 (44%), Gaps = 10/154 (6%)
Query: 57 GRYCANTIPDSTDTSSNTAVVRVWWGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQ 116
G + + P T NT + SQ S G +SP YP P+ W I +
Sbjct: 1987 GNHLSTPAPFLNITRPNTDYSCGGFLSQPS-GDFSSPFYPGNYPNNAKCVWDIEVQNNYR 2045
Query: 117 ITLTFSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFT 176
+T+ F +++L CN +++ VF+G +SP + ++C S SS N M + F +
Sbjct: 2046 VTVIFRDVQLEG--GCNYDYIEVFDGPYRSSPLIARVCDGARGS--FTSSSNFMSIRFIS 2101
Query: 177 DGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPN 210
D S GF A + SS D LC LPN
Sbjct: 2102 DHSITRRGFRAEYYSSPSNDSTNL--LC---LPN 2130
Score = 42.0 bits (97), Expect = 0.002
Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 7/65 (10%)
Query: 204 CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
CGG L + P G+F+SP Y G NY N C W + Q N + + F D LE C
Sbjct: 2008 CGGFL-SQPSGDFSSPFYPG--NYPNNAKCVWDIE--VQNNYRVTVIFRDVQLEG--GCN 2060
Query: 264 FDVLE 268
+D +E
Sbjct: 2061 YDYIE 2065
Score = 37.7 bits (86), Expect = 0.035
Identities = 24/65 (36%), Positives = 31/65 (47%), Gaps = 5/65 (7%)
Query: 204 CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
CGG L G F+SP Y Y N C W + N G I + F + LE+H +C
Sbjct: 1766 CGGFLFYA-SGTFSSPSYPAY--YPNNAKCVWEIE-VNSGYR-INLGFSNLKLEAHHNCS 1820
Query: 264 FDVLE 268
FD +E
Sbjct: 1821 FDYVE 1825
>gi|148539840 deleted in malignant brain tumors 1 isoform a precursor
[Homo sapiens]
Length = 1785
Score = 62.4 bits (150), Expect = 1e-09
Identities = 49/155 (31%), Positives = 74/155 (47%), Gaps = 12/155 (7%)
Query: 47 WDYHTSGNI--LGRYCANTIPDSTDTS----SNTAVVRVWWGSQG----SAGTSTSPNYP 96
W H G+ G C+ T +ST T + T R G ++GT +SP+YP
Sbjct: 1096 WLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYP 1155
Query: 97 NLNPHGRIYEWRITAPEGRQITLTFSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSS 156
P+ W I G +I L FSNL+L H +C+ ++V +F+G ++S L K+C+
Sbjct: 1156 AYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICN- 1214
Query: 157 VNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTS 191
+ SS N M + F +D S GF A + S
Sbjct: 1215 -DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1248
Score = 53.5 bits (127), Expect = 6e-07
Identities = 46/154 (29%), Positives = 68/154 (44%), Gaps = 10/154 (6%)
Query: 57 GRYCANTIPDSTDTSSNTAVVRVWWGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQ 116
G + + P T NT + SQ S G +SP YP P+ W I +
Sbjct: 1359 GNHLSTPAPFLNITRPNTDYSCGGFLSQPS-GDFSSPFYPGNYPNNAKCVWDIEVQNNYR 1417
Query: 117 ITLTFSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFT 176
+T+ F +++L CN +++ VF+G +SP + ++C S SS N M + F +
Sbjct: 1418 VTVIFRDVQLEG--GCNYDYIEVFDGPYRSSPLIARVCDGARGS--FTSSSNFMSIRFIS 1473
Query: 177 DGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPN 210
D S GF A + SS D LC LPN
Sbjct: 1474 DHSITRRGFRAEYYSSPSNDSTNL--LC---LPN 1502
Score = 42.0 bits (97), Expect = 0.002
Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 7/65 (10%)
Query: 204 CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
CGG L + P G+F+SP Y G NY N C W + Q N + + F D LE C
Sbjct: 1380 CGGFL-SQPSGDFSSPFYPG--NYPNNAKCVWDIE--VQNNYRVTVIFRDVQLEG--GCN 1432
Query: 264 FDVLE 268
+D +E
Sbjct: 1433 YDYIE 1437
Score = 37.7 bits (86), Expect = 0.035
Identities = 24/65 (36%), Positives = 31/65 (47%), Gaps = 5/65 (7%)
Query: 204 CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
CGG L G F+SP Y Y N C W + N G I + F + LE+H +C
Sbjct: 1138 CGGFLFYA-SGTFSSPSYPAY--YPNNAKCVWEIE-VNSGYR-INLGFSNLKLEAHHNCS 1192
Query: 264 FDVLE 268
FD +E
Sbjct: 1193 FDYVE 1197
>gi|54792129 discoidin, CUB and LCCL domain containing 2 [Homo
sapiens]
Length = 775
Score = 61.6 bits (148), Expect = 2e-09
Identities = 31/115 (26%), Positives = 59/115 (51%), Gaps = 1/115 (0%)
Query: 87 AGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRLATHLSCNSEHVIVFNGIRSN 146
+GT TS NYP P+ + EW I G ++ + F + + SC+ ++ ++NGI +
Sbjct: 81 SGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDIEDSDSCHFNYLRIYNGIGVS 140
Query: 147 SPQLEKLCS-SVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGC 200
++ K C + ++ I+S GN + ++F + GF AS++ + D + C
Sbjct: 141 RTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGFLASYSVIDKQDLITC 195
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.130 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,047,123
Number of Sequences: 37866
Number of extensions: 1369102
Number of successful extensions: 4934
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 65
Number of HSP's successfully gapped in prelim test: 72
Number of HSP's that attempted gapping in prelim test: 4272
Number of HSP's gapped (non-prelim): 498
length of query: 671
length of database: 18,247,518
effective HSP length: 109
effective length of query: 562
effective length of database: 14,120,124
effective search space: 7935509688
effective search space used: 7935509688
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.