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Search of human proteins with 119220564
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|119220564 one cut domain, family member 2 [Homo sapiens]
(504 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|119220564 one cut domain, family member 2 [Homo sapiens] 1042 0.0
gi|24307887 one cut homeobox 1 [Homo sapiens] 555 e-158
gi|122937424 one cut homeobox 3 [Homo sapiens] 426 e-119
gi|110347455 Brn3b POU domain transcription factor [Homo sapiens] 82 1e-15
gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens] 73 5e-13
gi|116517292 cut-like 2 [Homo sapiens] 69 1e-11
gi|5453936 POU class 3 homeobox 3 [Homo sapiens] 62 9e-10
gi|239757043 PREDICTED: functional smad suppressing element 18 [... 62 1e-09
gi|239751555 PREDICTED: functional smad suppressing element 18 [... 62 1e-09
gi|239746067 PREDICTED: functional smad suppressing element 18 [... 62 1e-09
gi|12751477 forkhead box L2 [Homo sapiens] 59 1e-08
gi|110347449 POU domain, class 4, transcription factor 1 [Homo s... 59 1e-08
gi|51702521 POU domain, class 3, transcription factor 2 [Homo sa... 59 1e-08
gi|4502565 calpain, small subunit 1 [Homo sapiens] 58 2e-08
gi|51599151 calpain, small subunit 1 [Homo sapiens] 58 2e-08
gi|20070107 orthodenticle homeobox 1 [Homo sapiens] 58 2e-08
gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding pro... 55 1e-07
gi|21322252 androgen receptor isoform 1 [Homo sapiens] 55 2e-07
gi|6912752 zinc finger protein 281 [Homo sapiens] 54 3e-07
gi|41281831 neuronal PAS domain protein 3 isoform 2 [Homo sapiens] 52 1e-06
gi|11545847 neuronal PAS domain protein 3 isoform 1 [Homo sapiens] 52 1e-06
gi|89145413 short stature homeobox 2 isoform a [Homo sapiens] 52 1e-06
gi|55770830 chromobox homolog 4 [Homo sapiens] 52 1e-06
gi|210147522 zinc finger, SWIM-type containing 6 [Homo sapiens] 52 1e-06
gi|18375613 dachshund homolog 1 isoform b [Homo sapiens] 52 2e-06
gi|18375611 dachshund homolog 1 isoform a [Homo sapiens] 52 2e-06
gi|18375609 dachshund homolog 1 isoform c [Homo sapiens] 52 2e-06
gi|55750053 atrophin-1 [Homo sapiens] 52 2e-06
gi|55750041 atrophin-1 [Homo sapiens] 52 2e-06
gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 52 2e-06
>gi|119220564 one cut domain, family member 2 [Homo sapiens]
Length = 504
Score = 1042 bits (2694), Expect = 0.0
Identities = 504/504 (100%), Positives = 504/504 (100%)
Query: 1 MKAAYTAYRCLTKDLEGCAMNPELTMESLGTLHGPAGGGSGGGGGGGGGGGGGGPGHEQE 60
MKAAYTAYRCLTKDLEGCAMNPELTMESLGTLHGPAGGGSGGGGGGGGGGGGGGPGHEQE
Sbjct: 1 MKAAYTAYRCLTKDLEGCAMNPELTMESLGTLHGPAGGGSGGGGGGGGGGGGGGPGHEQE 60
Query: 61 LLASPSPHHAGRGAAGSLRGPPPPPTAHQELGTAAAAAAAASRSAMVTSMASILDGGDYR 120
LLASPSPHHAGRGAAGSLRGPPPPPTAHQELGTAAAAAAAASRSAMVTSMASILDGGDYR
Sbjct: 61 LLASPSPHHAGRGAAGSLRGPPPPPTAHQELGTAAAAAAAASRSAMVTSMASILDGGDYR 120
Query: 121 PELSIPLHHAMSMSCDSSPPGMGMSNTYTTLTPLQPLPPISTVSDKFHHPHPHHHPHHHH 180
PELSIPLHHAMSMSCDSSPPGMGMSNTYTTLTPLQPLPPISTVSDKFHHPHPHHHPHHHH
Sbjct: 121 PELSIPLHHAMSMSCDSSPPGMGMSNTYTTLTPLQPLPPISTVSDKFHHPHPHHHPHHHH 180
Query: 181 HHHHQRLSGNVSGSFTLMRDERGLPAMNNLYSPYKEMPGMSQSLSPLAATPLGNGLGGLH 240
HHHHQRLSGNVSGSFTLMRDERGLPAMNNLYSPYKEMPGMSQSLSPLAATPLGNGLGGLH
Sbjct: 181 HHHHQRLSGNVSGSFTLMRDERGLPAMNNLYSPYKEMPGMSQSLSPLAATPLGNGLGGLH 240
Query: 241 NAQQSLPNYGPPGHDKMLSPNFDAHHTAMLTRGEQHLSRGLGTPPAAMMSHLNGLHHPGH 300
NAQQSLPNYGPPGHDKMLSPNFDAHHTAMLTRGEQHLSRGLGTPPAAMMSHLNGLHHPGH
Sbjct: 241 NAQQSLPNYGPPGHDKMLSPNFDAHHTAMLTRGEQHLSRGLGTPPAAMMSHLNGLHHPGH 300
Query: 301 TQSHGPVLAPSRERPPSSSSGSQVATSGQLEEINTKEVAQRITAELKRYSIPQAIFAQRV 360
TQSHGPVLAPSRERPPSSSSGSQVATSGQLEEINTKEVAQRITAELKRYSIPQAIFAQRV
Sbjct: 301 TQSHGPVLAPSRERPPSSSSGSQVATSGQLEEINTKEVAQRITAELKRYSIPQAIFAQRV 360
Query: 361 LCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRKEQEPNK 420
LCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRKEQEPNK
Sbjct: 361 LCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRKEQEPNK 420
Query: 421 DRNNSQKKSRLVFTDLQRRTLFAIFKENKRPSKEMQITISQQLGLELTTVSNFFMNARRR 480
DRNNSQKKSRLVFTDLQRRTLFAIFKENKRPSKEMQITISQQLGLELTTVSNFFMNARRR
Sbjct: 421 DRNNSQKKSRLVFTDLQRRTLFAIFKENKRPSKEMQITISQQLGLELTTVSNFFMNARRR 480
Query: 481 SLEKWQDDLSTGGSSSTSSTCTKA 504
SLEKWQDDLSTGGSSSTSSTCTKA
Sbjct: 481 SLEKWQDDLSTGGSSSTSSTCTKA 504
>gi|24307887 one cut homeobox 1 [Homo sapiens]
Length = 465
Score = 555 bits (1431), Expect = e-158
Identities = 324/513 (63%), Positives = 366/513 (71%), Gaps = 76/513 (14%)
Query: 20 MNPELTMESLGTLHGPAGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLR 79
MN +LTME++G LHG + P L SPH A R
Sbjct: 1 MNAQLTMEAIGELHGVS----------------HEPVPAPADLLGGSPHARSSVAH---R 41
Query: 80 GPPPPPTAHQELGTAAAAAAAASRSAMVTSMASILD----GGDYR-----PELSI--PLH 128
G PP + +G MAS+LD GGDY PE S+ PLH
Sbjct: 42 GSHLPPAHPRSMG-----------------MASLLDGGSGGGDYHHHHRAPEHSLAGPLH 84
Query: 129 HAMSMSCDSSPPGMGMSNTYTTLTPLQPLPPISTVSDKFHHPHPHHHPHHHHHHHHQRLS 188
M+M+C+ +PPGM M TYTTLTPLQPLPPISTVSDKF H H HHH HHHH HHHQRL+
Sbjct: 85 PTMTMACE-TPPGMSMPTTYTTLTPLQPLPPISTVSDKFPH-HHHHHHHHHHPHHHQRLA 142
Query: 189 GNVSGSFTLMRDERGLPAMNNLYSPY-KEMPGMSQSLSPLAATPLGNGLGGLHNAQQSLP 247
GNVSGSFTLMRDERGL +MNNLY+PY K++ GM QSLSPL++ +GLG +HN+QQ LP
Sbjct: 143 GNVSGSFTLMRDERGLASMNNLYTPYHKDVAGMGQSLSPLSS----SGLGSIHNSQQGLP 198
Query: 248 NYGPPG----HDKMLSPN-FDAHHTAMLTR-GEQHLSRGLGTPPAAMMSHLNGL--HHPG 299
+Y PG DKML+PN F+AHH AML R GEQHL TP +A M +NGL HHP
Sbjct: 199 HYAHPGAAMPTDKMLTPNGFEAHHPAMLGRHGEQHL-----TPTSAGMVPINGLPPHHPH 253
Query: 300 ---HTQSHGPVLAPSRERPPSSSSGSQV---ATSGQLEEINTKEVAQRITAELKRYSIPQ 353
+ Q HG +L +RE P S +G+QV + SGQ+EEINTKEVAQRIT ELKRYSIPQ
Sbjct: 254 AHLNAQGHGQLLGTARE-PNPSVTGAQVSNGSNSGQMEEINTKEVAQRITTELKRYSIPQ 312
Query: 354 AIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKR 413
AIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKR
Sbjct: 313 AIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKR 372
Query: 414 KEQEPNKDRNNSQKKSRLVFTDLQRRTLFAIFKENKRPSKEMQITISQQLGLELTTVSNF 473
KEQE KDR N+ KK RLVFTD+QRRTL AIFKENKRPSKE+QITISQQLGLEL+TVSNF
Sbjct: 373 KEQEHGKDRGNTPKKPRLVFTDVQRRTLHAIFKENKRPSKELQITISQQLGLELSTVSNF 432
Query: 474 FMNARRRSLEKWQDDLS--TGGSSSTSSTCTKA 504
FMNARRRSL+KWQD+ S +G SSS+SSTCTKA
Sbjct: 433 FMNARRRSLDKWQDEGSSNSGNSSSSSSTCTKA 465
>gi|122937424 one cut homeobox 3 [Homo sapiens]
Length = 494
Score = 426 bits (1096), Expect = e-119
Identities = 281/548 (51%), Positives = 319/548 (58%), Gaps = 121/548 (22%)
Query: 23 ELTMESLGTLHGPAGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPP 82
EL++ESLG LH A +G ELL SP HA R AA RG
Sbjct: 2 ELSLESLGGLHSVAHAQAG------------------ELL---SPGHA-RSAAAQHRG-- 37
Query: 83 PPPTAHQELGTAAAAAAAASRSAMVTSMASILDGG---------------------DYRP 121
A R +V MAS+LDGG D+R
Sbjct: 38 ---------------LVAPGRPGLVAGMASLLDGGGGGGGGGAGGAGGAGSAGGGADFRG 82
Query: 122 ELSIPLHHAMSMSCDSSPPGMGMSNTYTTLTPLQPLPPISTVSDKFHHP----------- 170
EL+ PLH AM M+C++ PG+G TYTTLTPLQ LPP++ V+DKFH
Sbjct: 83 ELAGPLHPAMGMACEA--PGLG--GTYTTLTPLQHLPPLAAVADKFHQHAAAAAVAGAHG 138
Query: 171 -HPHHHPHHHHHHHH----QRLSGNVSGSFTLMRDERG-LPAMNNLYSPY-KEMPGMSQS 223
HPH HPH QRL+ +VSGSFTLMRDER L ++ +LY PY KE+P M
Sbjct: 139 GHPHAHPHPAAAPPPPPPPQRLAASVSGSFTLMRDERAALASVGHLYGPYGKELPAMGSP 198
Query: 224 LSPLAATPLGNGLG-GLHNAQQSLPN--------YGPPGH---DKMLSPNFDAHHTAMLT 271
LSPL N L LH A Q P YGPPGH DK+L P H A+L
Sbjct: 199 LSPLP-----NALPPALHGAPQPPPPPPPPPLAAYGPPGHLAGDKLLPPAAFEPHAALLG 253
Query: 272 RGEQHLSRGL-----GT--------PPAAMMSHLNGLHHPGHTQSHGPVLAPSRERPPSS 318
R E L+RGL GT A +++ L GL G HG P
Sbjct: 254 RAEDALARGLPGGGGGTGSGGAGSGSAAGLLAPLGGLAAAGAHGPHGGGGGPG------- 306
Query: 319 SSGSQVATSGQLEEINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPW 378
SG + EEINTKEVAQRITAELKRYSIPQAIFAQR+LCRSQGTLSDLLRNPKPW
Sbjct: 307 GSGGGPSAGAAAEEINTKEVAQRITAELKRYSIPQAIFAQRILCRSQGTLSDLLRNPKPW 366
Query: 379 SKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRKEQEPNKDRNNSQKKSRLVFTDLQR 438
SKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRKEQE K+R KK RLVFTDLQR
Sbjct: 367 SKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRKEQEQQKERALQPKKQRLVFTDLQR 426
Query: 439 RTLFAIFKENKRPSKEMQITISQQLGLELTTVSNFFMNARRRSLEKWQDDLST--GGSSS 496
RTL AIFKENKRPSKEMQ+TISQQLGLEL TVSNFFMNARRR + +W ++ ST GG +
Sbjct: 427 RTLIAIFKENKRPSKEMQVTISQQLGLELNTVSNFFMNARRRCMNRWAEEPSTAPGGPAG 486
Query: 497 TSSTCTKA 504
++T +KA
Sbjct: 487 ATATFSKA 494
Score = 35.4 bits (80), Expect = 0.12
Identities = 32/95 (33%), Positives = 36/95 (37%), Gaps = 13/95 (13%)
Query: 15 LEGCAMNPELTMESLGTLHGPAGGGSGGGGGGGGGG---GGGGPGHEQELLA-------- 63
L G + P E L G A G GGGGG GG G G LLA
Sbjct: 234 LAGDKLLPPAAFEPHAALLGRAEDALARGLPGGGGGTGSGGAGSGSAAGLLAPLGGLAAA 293
Query: 64 -SPSPHHAGRGAAGSLRGPPPPPTAHQELGTAAAA 97
+ PH G G GS G P A +E+ T A
Sbjct: 294 GAHGPHGGGGGPGGS-GGGPSAGAAAEEINTKEVA 327
>gi|110347455 Brn3b POU domain transcription factor [Homo sapiens]
Length = 409
Score = 82.0 bits (201), Expect = 1e-15
Identities = 113/454 (24%), Positives = 160/454 (35%), Gaps = 109/454 (24%)
Query: 35 PAGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPPPPTAHQELGTA 94
P+ + GGGGGGGGGGGGG G +S S G A P PP L +
Sbjct: 47 PSSSSNAGGGGGGGGGGGGGGGRSSSSSSSGSSGGGGSEAMRRACLPTPPSNIFGGLDES 106
Query: 95 AAAAAAASRSAMVTSMASILDGGDYRPELSIPLHHAMSMSCDSSPPGMGMSNTYTTLTPL 154
A A A + + S + + P HH SP TY T+ +
Sbjct: 107 LLARAEALAAVDIVSQS--------KSHHHHPPHH--------SP--FKPDATYHTMNTI 148
Query: 155 QPLPPISTVSDKFHHPH----PHHHPHHHHHHHHQRLSGNVSGSFTLMRDERGLPAMNNL 210
S+ S HP HHH HHHHHHHHQ
Sbjct: 149 PCTSAASSSSVPISHPSALAGTHHHHHHHHHHHHQ------------------------- 183
Query: 211 YSPYKEMPG-MSQSLSPLAATPLGNGLGGLHNAQQSLPNYGPPGHDKMLSPNFDAHHTAM 269
P++ + G + + LSP G LG + GP G + AH M
Sbjct: 184 --PHQALEGELLEHLSP------GLALGAM---------AGPDG----AVVSTPAHAPHM 222
Query: 270 LTRGEQHLSRGLGTPPAAMMSHLNGLHHPGHTQSHGPVLAPSRERPPSSSSGSQVATSGQ 329
T H + A M+H +GL P H V A R+ + Q
Sbjct: 223 ATMNPMHQA-------ALSMAHAHGL--PSHMGCMSDVDADPRDLEAFAERFKQ------ 267
Query: 330 LEEINTKEVAQRITAELKRYSIP-QAIFAQRVLCRSQG-TLS-DLLRNPKPWSKLKSGRE 386
I + + L IP +Q +CR + TLS + + KP
Sbjct: 268 -RRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNMIALKP--------- 317
Query: 387 TFRRMWKWLQEPEFQRMSALRLAACKRKEQEPNKDRNNSQKKSRLVFTDLQRRTLFAIFK 446
+ WL+E E + + K +P +K+ R ++R+L A F
Sbjct: 318 ---ILQAWLEEAE---------KSHREKLTKPELFNGAEKKRKRTSIAAPEKRSLEAYFA 365
Query: 447 ENKRPSKEMQITISQQLGLELTTVSNFFMNARRR 480
RPS E I+++L L+ V +F N R++
Sbjct: 366 IQPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQK 399
>gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens]
Length = 1505
Score = 73.2 bits (178), Expect = 5e-13
Identities = 57/208 (27%), Positives = 92/208 (44%), Gaps = 37/208 (17%)
Query: 306 PVLAPSRERPPSSSSGSQVATSGQL----EEINTKEVAQRITAELKRYSIPQAIFAQRVL 361
P + S+ P SG + +L E++T + +R+ L ++ Q +F + +L
Sbjct: 1095 PPASDSQPTTPLPLSGHSALSIQELVAMSPELDTYGITKRVKEVLTDNNLGQRLFGETIL 1154
Query: 362 CRSQGTLSDLLRNPKPWSKLK-SGRETFRRMWKWLQEPEFQRMSALRLAACKRKEQEPNK 420
+QG++SDLL PKPW KL GRE F RM WL +P + +L KR E++
Sbjct: 1155 GLTQGSVSDLLARPKPWHKLSLKGREPFVRMQLWLNDPN----NVEKLMDMKRMEKKAYM 1210
Query: 421 DRNNSQ----------------------------KKSRLVFTDLQRRTLFAIFKENKRPS 452
R +S KK R+V ++ L +++ PS
Sbjct: 1211 KRRHSSVSDSQPCEPPSVGTEYSQGASPQPQHQLKKPRVVLAPEEKEALKRAYQQKPYPS 1270
Query: 453 KEMQITISQQLGLELTTVSNFFMNARRR 480
+ ++ QL L+ +TV N+F N R R
Sbjct: 1271 PKTIEDLATQLNLKTSTVINWFHNYRSR 1298
Score = 67.0 bits (162), Expect = 4e-11
Identities = 42/122 (34%), Positives = 69/122 (56%), Gaps = 13/122 (10%)
Query: 316 PSSSSGSQVATSGQLEEINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNP 375
PS S + + EE++T E+A+++ +L +++I Q IF VL SQG++S++L P
Sbjct: 534 PSPSQSESAGSVSEGEEMDTAEIARQVKEQLIKHNIGQRIFGHYVLGLSQGSVSEILARP 593
Query: 376 KPWSKLK-SGRETFRRMWKWLQEPEFQRMSALRLAACKRKE----------QEPNKDRNN 424
KPW+KL G+E F +M ++L + Q + ALR +++E QE K RN
Sbjct: 594 KPWNKLTVRGKEPFHKMKQFLSDE--QNILALRSIQGRQRENPGQSLNRLFQEVPKRRNG 651
Query: 425 SQ 426
S+
Sbjct: 652 SE 653
Score = 62.8 bits (151), Expect = 7e-10
Identities = 31/66 (46%), Positives = 46/66 (69%), Gaps = 1/66 (1%)
Query: 331 EEINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKL-KSGRETFR 389
+E++T E+ +++ +L + I Q IF ++VL SQG++SD+L PKPWSKL + GRE F
Sbjct: 941 QEVDTIELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFI 1000
Query: 390 RMWKWL 395
RM WL
Sbjct: 1001 RMQLWL 1006
>gi|116517292 cut-like 2 [Homo sapiens]
Length = 1486
Score = 68.6 bits (166), Expect = 1e-11
Identities = 68/226 (30%), Positives = 98/226 (43%), Gaps = 40/226 (17%)
Query: 201 ERGLPAMNNLYSPYKEMPGMSQSLSPLAATPLGNGLGGLHNAQQSLPNYGPPGHDKMLSP 260
E+ P+ L P PG LSP PL LG P+ GP G +
Sbjct: 436 EQSYPSPQQLPPP----PGPEDPLSPSPGQPL---LG---------PSLGPDG-----TR 474
Query: 261 NFDAHHTAMLTRGEQHLSRGLGTPPAAMMSHLNGLH-HPGHTQSHGPVLAPSRERP---- 315
F L GE+ L PPAA GL P P AP+ P
Sbjct: 475 TFSLSPFPSLASGER-----LMMPPAAFKGEAGGLLVFPPAFYGAKPPTAPATPAPGPEP 529
Query: 316 -----PSSSSGSQVATSGQLEE-INTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLS 369
P+ G A G EE ++T E+A ++ +L +++I Q +F VL SQG++S
Sbjct: 530 LGGPEPADGGGGGAAGPGAEEEQLDTAEIAFQVKEQLLKHNIGQRVFGHYVLGLSQGSVS 589
Query: 370 DLLRNPKPWSKLK-SGRETFRRMWKWLQEPEFQRMSALRLAACKRK 414
++L PKPW KL G+E F +M ++L + Q + ALR +++
Sbjct: 590 EILARPKPWRKLTVKGKEPFIKMKQFLSDE--QNVLALRTIQVRQR 633
Score = 67.8 bits (164), Expect = 2e-11
Identities = 50/177 (28%), Positives = 81/177 (45%), Gaps = 28/177 (15%)
Query: 332 EINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLK-SGRETFRR 390
E++T + +R+ L ++ Q +F + +L +QG++SDLL PKPW KL GRE F R
Sbjct: 1046 ELDTYSITKRVKEVLTDNNLGQRLFGESILGLTQGSVSDLLSRPKPWHKLSLKGREPFVR 1105
Query: 391 MWKWLQEP----EFQRMSALRLAACKRKEQEPNKDRNNSQ-------------------- 426
M WL +P + + M L A ++ ++S+
Sbjct: 1106 MQLWLNDPHNVEKLRDMKKLEKKAYLKRRYGLISTGSDSESPATRSECPSPCLQPQDLSL 1165
Query: 427 ---KKSRLVFTDLQRRTLFAIFKENKRPSKEMQITISQQLGLELTTVSNFFMNARRR 480
KK R+V ++ L ++ PS++ +S QL L+ TV N+F N R R
Sbjct: 1166 LQIKKPRVVLAPEEKEALRKAYQLEPYPSQQTIELLSFQLNLKTNTVINWFHNYRSR 1222
Score = 63.9 bits (154), Expect = 3e-10
Identities = 43/142 (30%), Positives = 69/142 (48%), Gaps = 19/142 (13%)
Query: 332 EINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKL-KSGRETFRR 390
E++T E+ +++ +L + I Q IF ++VL SQG++SD+L PKPWSKL + GRE F R
Sbjct: 895 EVDTLELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIR 954
Query: 391 MWKWL---------QEPEFQRMSALRLAACKRKEQEPNKDRNNSQKKSRLVFTDLQRRTL 441
M WL Q+P + S + P + +SQ+ L
Sbjct: 955 MQLWLSDQLGQAVGQQPGASQASPTEPRSSPSPPPSPTEPEKSSQEPLSLSLES------ 1008
Query: 442 FAIFKENKRPSKEMQITISQQL 463
KEN++P ++S ++
Sbjct: 1009 ---SKENQQPEGRSSSSLSGKM 1027
Score = 29.6 bits (65), Expect = 6.7
Identities = 16/31 (51%), Positives = 17/31 (54%), Gaps = 3/31 (9%)
Query: 35 PAGGGSGGGG---GGGGGGGGGGPGHEQELL 62
PA G GG GGGGG GPG E+E L
Sbjct: 523 PAPGPEPLGGPEPADGGGGGAAGPGAEEEQL 553
>gi|5453936 POU class 3 homeobox 3 [Homo sapiens]
Length = 500
Score = 62.4 bits (150), Expect = 9e-10
Identities = 121/492 (24%), Positives = 167/492 (33%), Gaps = 104/492 (21%)
Query: 34 GPAGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAG-------------RGAAGSLRG 80
G GGG GGGGGGGGG GGGG G + A S + G +GA + G
Sbjct: 28 GAGGGGGGGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGDPSSVKMVQSDFMQGAMAASNG 87
Query: 81 PPPPPTAHQEL--------GTAAAAAAAASRSAMVTSMASILDGGDYRPELSIPLHHAMS 132
AHQ + AAAAAAA S+ + A + G +P P
Sbjct: 88 GHMLSHAHQWVTALPHAAAAAAAAAAAAVEASSPWSGSAVGMAGSPQQPPQPPP------ 141
Query: 133 MSCDSSPP-------GMGMSNTYTTLTPLQPLPPISTVSDKFHHPHPHHHPHHHHHHHHQ 185
PP G G + + PP H P P H H
Sbjct: 142 -----PPPQGPDVKGGAGRDDLHAGTALHHRGPP---------HLGPPPPPPHQGHPGGW 187
Query: 186 RLSGNVSGSFTLMRDERGLPAMNNLYSPYKE-----MPGMSQSLSPLAATP-LGNGLGGL 239
+ + + LP+M P + PG L+A P G G GG
Sbjct: 188 GAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQSLLYSQPGGFTVNGMLSAPPGPGGGGGGA 247
Query: 240 HNAQQSLPNYGPPGHDKMLSPNFDAHHTAMLTRGEQHLSRGLGTPPAAMMSHLNG-LHHP 298
QSL + PG + +P HH H PP H G HH
Sbjct: 248 GGGAQSLVH---PGLVRGDTPELAEHH-------HHHHHHAHPHPPHP--HHAQGPPHHG 295
Query: 299 GHTQSHGPVLAPSRERPPSSSSGSQVATSGQLEEINTKEVAQRITAELKRYSIPQA---- 354
G GP L S TS LE+ + +RI + + A
Sbjct: 296 GGGGGAGPGL-----NSHDPHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADVGLALGTL 350
Query: 355 ---IFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSAL---RL 408
+F+Q +CR + L + K KLK + KWL+E + S ++
Sbjct: 351 YGNVFSQTTICRFEA----LQLSFKNMCKLKP------LLNKWLEEADSSTGSPTSIDKI 400
Query: 409 AACKRKEQEPNKDRNNSQKKSRLVFTDLQRRTLFAIFKENKRPSKEMQITISQQLGLELT 468
AA RK +K R + L + F + +PS + ++ L LE
Sbjct: 401 AAQGRK------------RKKRTSIEVSVKGALESHFLKCPKPSAQEITNLADSLQLEKE 448
Query: 469 TVSNFFMNARRR 480
V +F N R++
Sbjct: 449 VVRVWFCNRRQK 460
Score = 33.9 bits (76), Expect = 0.36
Identities = 22/63 (34%), Positives = 24/63 (38%), Gaps = 4/63 (6%)
Query: 30 GTLHGPAGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPPPPTAHQ 89
G L P G G GGGG GGG PG L+ +P A P PP H
Sbjct: 232 GMLSAPPGPGGGGGGAGGGAQSLVHPG----LVRGDTPELAEHHHHHHHHAHPHPPHPHH 287
Query: 90 ELG 92
G
Sbjct: 288 AQG 290
>gi|239757043 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 996
Score = 62.0 bits (149), Expect = 1e-09
Identities = 54/185 (29%), Positives = 66/185 (35%), Gaps = 29/185 (15%)
Query: 17 GCAM--NPELTMESLGTLHGPAGGGSGG---------------GGGGGGGGGGGGPGHEQ 59
GCA+ +P L ++ L P G G G G GG G
Sbjct: 496 GCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPPPAGGAGSRD 555
Query: 60 ELLASPSPHHAGRGAAGSLRGPPPPPTAHQELGTAAAAAAAASRSAMVTSMASILDGGDY 119
L SP G +AGS PP A G AAA + A +L+G
Sbjct: 556 ALFESPPGGSGGDCSAGST--PPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLLEG--- 610
Query: 120 RPELSIPLHHAMSMSCDSSPPGMGMSNTYTTLTPLQPLPPISTVSDKFHHPHPHHHPHHH 179
R HH+ S G + + L P S + HPH HHHPHHH
Sbjct: 611 RKAGGGSYHHS---SAFRPVGGKDDAESLAKLHGASAGAPHSAQT----HPHHHHHPHHH 663
Query: 180 HHHHH 184
HHHHH
Sbjct: 664 HHHHH 668
Score = 33.1 bits (74), Expect = 0.61
Identities = 21/58 (36%), Positives = 23/58 (39%), Gaps = 11/58 (18%)
Query: 28 SLGTLHGPAGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPPPP 85
SL G G+GGGG GGG G G G AG GA +GP P
Sbjct: 335 SLSVAAASGGAGTGGGGAGGGCVAGVGVG-----------AGAGAGAGAGAKGPRSYP 381
>gi|239751555 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 62.0 bits (149), Expect = 1e-09
Identities = 54/185 (29%), Positives = 66/185 (35%), Gaps = 29/185 (15%)
Query: 17 GCAM--NPELTMESLGTLHGPAGGGSGG---------------GGGGGGGGGGGGPGHEQ 59
GCA+ +P L ++ L P G G G G GG G
Sbjct: 496 GCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPPPAGGAGSRD 555
Query: 60 ELLASPSPHHAGRGAAGSLRGPPPPPTAHQELGTAAAAAAAASRSAMVTSMASILDGGDY 119
L SP G +AGS PP A G AAA + A +L+G
Sbjct: 556 ALFESPPGGSGGDCSAGST--PPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLLEG--- 610
Query: 120 RPELSIPLHHAMSMSCDSSPPGMGMSNTYTTLTPLQPLPPISTVSDKFHHPHPHHHPHHH 179
R HH+ S G + + L P S + HPH HHHPHHH
Sbjct: 611 RKAGGGSYHHS---SAFRPVGGKDDAESLAKLHGASAGAPHSAQT----HPHHHHHPHHH 663
Query: 180 HHHHH 184
HHHHH
Sbjct: 664 HHHHH 668
Score = 33.1 bits (74), Expect = 0.61
Identities = 21/58 (36%), Positives = 23/58 (39%), Gaps = 11/58 (18%)
Query: 28 SLGTLHGPAGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPPPP 85
SL G G+GGGG GGG G G G AG GA +GP P
Sbjct: 335 SLSVAAASGGAGTGGGGAGGGCVAGVGVG-----------AGAGAGAGAGAKGPRSYP 381
>gi|239746067 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 62.0 bits (149), Expect = 1e-09
Identities = 54/185 (29%), Positives = 66/185 (35%), Gaps = 29/185 (15%)
Query: 17 GCAM--NPELTMESLGTLHGPAGGGSGG---------------GGGGGGGGGGGGPGHEQ 59
GCA+ +P L ++ L P G G G G GG G
Sbjct: 496 GCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPPPAGGAGSRD 555
Query: 60 ELLASPSPHHAGRGAAGSLRGPPPPPTAHQELGTAAAAAAAASRSAMVTSMASILDGGDY 119
L SP G +AGS PP A G AAA + A +L+G
Sbjct: 556 ALFESPPGGSGGDCSAGST--PPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLLEG--- 610
Query: 120 RPELSIPLHHAMSMSCDSSPPGMGMSNTYTTLTPLQPLPPISTVSDKFHHPHPHHHPHHH 179
R HH+ S G + + L P S + HPH HHHPHHH
Sbjct: 611 RKAGGGSYHHS---SAFRPVGGKDDAESLAKLHGASAGAPHSAQT----HPHHHHHPHHH 663
Query: 180 HHHHH 184
HHHHH
Sbjct: 664 HHHHH 668
Score = 33.1 bits (74), Expect = 0.61
Identities = 21/58 (36%), Positives = 23/58 (39%), Gaps = 11/58 (18%)
Query: 28 SLGTLHGPAGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPPPP 85
SL G G+GGGG GGG G G G AG GA +GP P
Sbjct: 335 SLSVAAASGGAGTGGGGAGGGCVAGVGVG-----------AGAGAGAGAGAKGPRSYP 381
>gi|12751477 forkhead box L2 [Homo sapiens]
Length = 376
Score = 58.9 bits (141), Expect = 1e-08
Identities = 56/150 (37%), Positives = 69/150 (46%), Gaps = 23/150 (15%)
Query: 39 GSGGGGGGGGGGGGGGPGHEQELLASPSPHHAG-RGAAGSLRGPPPP-PTAHQELGTAAA 96
G+GG GG G G G G+ LA P +G + L PP P P A ++ AAA
Sbjct: 168 GAGGAAGGCGVAGAGADGYGY--LAPPKYLQSGFLNNSWPLPQPPSPMPYASCQMAAAAA 225
Query: 97 AAAAASRSAMVTSM-ASILDGGDYRPELSI-PLHHAMSMSCDSSPPGMGMSNTYTTL--T 152
AAAAA+ +A S A+ + G P S P SM+ PPG+ N+Y L
Sbjct: 226 AAAAAAAAAGPGSPGAAAVVKGLAGPAASYGPYTRVQSMAL---PPGV--VNSYNGLGGP 280
Query: 153 PLQPLPPISTVSDKFHHPHPHHHPHHHHHH 182
P P PP PHPH HPH HH H
Sbjct: 281 PAAPPPP----------PHPHPHPHAHHLH 300
Score = 30.8 bits (68), Expect = 3.0
Identities = 34/130 (26%), Positives = 41/130 (31%), Gaps = 23/130 (17%)
Query: 202 RGLPAMNNLYSPYKEMPGMSQSLSPLAATPLGNGLGGLHNAQQSLPNYGPPGHDKMLSPN 261
+GL Y PY + M+ P NGLGG A P+ P H
Sbjct: 246 KGLAGPAASYGPYTRVQSMAL---PPGVVNSYNGLGGPPAAPPPPPHPHPHPH------- 295
Query: 262 FDAHHTAMLTRGEQHLSRGLGTPPAAMMSHLNGLHHPGHTQSHGPVLAPSRERPPSSSSG 321
AHH PP A H PG P A P+S+ G
Sbjct: 296 --AHHL-----------HAAAAPPPAPPHHGAAAPPPGQLSPASPATAAPPAPAPTSAPG 342
Query: 322 SQVATSGQLE 331
Q A + Q E
Sbjct: 343 LQFACARQPE 352
Score = 29.6 bits (65), Expect = 6.7
Identities = 32/112 (28%), Positives = 39/112 (34%), Gaps = 7/112 (6%)
Query: 36 AGGGSGGGG----GGGGGGGGGGP-GHEQELLASPSPHHAGRGAAGSLRGPPPPPTAHQE 90
AG GS G G G GP Q + P ++ G G PPPPP H
Sbjct: 234 AGPGSPGAAAVVKGLAGPAASYGPYTRVQSMALPPGVVNSYNGLGGPPAAPPPPPHPHPH 293
Query: 91 LGTAAAAAAAASRSAMVTSMASILDGGDYRPELSIPLHHAMSMSCDSSPPGM 142
AAAA A A+ G P + P A +S PG+
Sbjct: 294 PHAHHLHAAAAPPPAPPHHGAAAPPPGQLSP--ASPATAAPPAPAPTSAPGL 343
>gi|110347449 POU domain, class 4, transcription factor 1 [Homo
sapiens]
Length = 419
Score = 58.9 bits (141), Expect = 1e-08
Identities = 43/97 (44%), Positives = 48/97 (49%), Gaps = 16/97 (16%)
Query: 34 GPAGGGSGGGGGGGGGGGGGGPGHEQELL---ASPSPH--------HAGRGAAGSLRGPP 82
G GGG GGGGGGG GGGGGGPG LL A P PH H AA ++
Sbjct: 157 GGPGGGPGGGGGGGPGGGGGGPG--GGLLGGSAHPHPHMHSLGHLSHPAAAAAMNMPSGL 214
Query: 83 PPP---TAHQELGTAAAAAAAASRSAMVTSMASILDG 116
P P A G AAAAAAAA+ S A+ + G
Sbjct: 215 PHPGLVAAAAHHGAAAAAAAAAAGQVAAASAAAAVVG 251
Score = 49.3 bits (116), Expect = 8e-06
Identities = 92/370 (24%), Positives = 137/370 (37%), Gaps = 77/370 (20%)
Query: 147 TYTTLTPLQPLPPISTVSDKFHHPHPHHHPHHHHHHHHQRLS-GNV-----SGSFTLMRD 200
TY T+ + P STV P HHH HHHHHHQ L G++ S S LM
Sbjct: 81 TYHTMNSV-PCTSTSTV------PLAHHH---HHHHHHQALEPGDLLDHISSPSLALMAG 130
Query: 201 ERGLPAMNNLYSPYKEMPGMSQSLSPLAATPLGNGLGGLHNAQQSLPNYGPPGHDKMLSP 260
G A + G P G G GG GP G +L
Sbjct: 131 AGGAGAAAGGGGAHD---GPGGGGGPGGGGGPGGGPGGGGGGGPGGGGGGPGGG--LLGG 185
Query: 261 NFDAH-HTAMLTRGEQHLSRGLGTPPAAMMSHLNGLHHPG-------HTQSHGPVLAPSR 312
+ AH H M + G HLS AA M+ +GL HPG H + A +
Sbjct: 186 S--AHPHPHMHSLG--HLSHPAA---AAAMNMPSGLPHPGLVAAAAHHGAAAAAAAAAAG 238
Query: 313 ERPPSSSSGSQVATSG------------QLEEINTKEVAQRITAELKRYSIPQAI----- 355
+ +S++ + V +G +LE + +RI + + + A+
Sbjct: 239 QVAAASAAAAVVGAAGLASICDSDTDPRELEAFAERFKQRRIKLGVTQADVGSALANLKI 298
Query: 356 -----FAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAA 410
+Q +CR + L + LK + WL+E E A
Sbjct: 299 PGVGSLSQSTICRFES----LTLSHNNMIALKPILQA------WLEEAE---------GA 339
Query: 411 CKRKEQEPNKDRNNSQKKSRLVFTDLQRRTLFAIFKENKRPSKEMQITISQQLGLELTTV 470
+ K +P +K+ R ++R+L A F RPS E I+++L L+ V
Sbjct: 340 QREKMNKPELFNGGEKKRKRTSIAAPEKRSLEAYFAVQPRPSSEKIAAIAEKLDLKKNVV 399
Query: 471 SNFFMNARRR 480
+F N R++
Sbjct: 400 RVWFCNQRQK 409
Score = 45.4 bits (106), Expect = 1e-04
Identities = 33/88 (37%), Positives = 39/88 (44%), Gaps = 9/88 (10%)
Query: 24 LTMESLGTLHGPAGGGSGGGGGG-----GGG---GGGGGPGHEQELLASPSPHHAGRGAA 75
++ SL + G G G+ GGGG GGG GGGGGPG P G G
Sbjct: 120 ISSPSLALMAGAGGAGAAAGGGGAHDGPGGGGGPGGGGGPGGGPGGGGGGGPGGGGGGPG 179
Query: 76 GSLRGPPPPPTAH-QELGTAAAAAAAAS 102
G L G P H LG + AAAA+
Sbjct: 180 GGLLGGSAHPHPHMHSLGHLSHPAAAAA 207
>gi|51702521 POU domain, class 3, transcription factor 2 [Homo
sapiens]
Length = 443
Score = 58.5 bits (140), Expect = 1e-08
Identities = 51/177 (28%), Positives = 63/177 (35%), Gaps = 29/177 (16%)
Query: 33 HGPAGGGSGGGGGGGGGGGGGGPGH--------EQELLASPSPHHAGRGAAGSLRGPPPP 84
HG GGG GGGGGGGGGGGGGG G + ++ S GRG L GP
Sbjct: 67 HGGGGGGGGGGGGGGGGGGGGGDGSPWSTSPLGQPDIKPSVVVQQGGRG--DELHGPGAL 124
Query: 85 PTAHQELGTAAAAAAAASRSAMVTSMASIL--DGGDYRPELSIPLHHAMSMSCDSSPPGM 142
HQ+ + L ++ P P + + PP M
Sbjct: 125 QQQHQQQQQQQQQQQQQQQQQQQQQRPPHLVHHAANHHPG---PGAWRSAAAAAHLPPSM 181
Query: 143 GMSN-----TYTTLTPLQPLPPISTVSDKFHH---------PHPHHHPHHHHHHHHQ 185
G SN + + T L + HH H HHPH H H H Q
Sbjct: 182 GASNGGLLYSQPSFTVNGMLGAGGQPAGLHHHGLRDAHDEPHHADHHPHPHSHPHQQ 238
>gi|4502565 calpain, small subunit 1 [Homo sapiens]
Length = 268
Score = 57.8 bits (138), Expect = 2e-08
Identities = 31/60 (51%), Positives = 32/60 (53%), Gaps = 2/60 (3%)
Query: 29 LGTLHGPAGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPPPPTAH 88
LG L AGGG GGGGGGGGGGGGGG G +L A AA PPPP H
Sbjct: 29 LGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRILGGVI--SAISEAAAQYNPEPPPPRTH 86
Score = 38.9 bits (89), Expect = 0.011
Identities = 31/99 (31%), Positives = 41/99 (41%), Gaps = 15/99 (15%)
Query: 41 GGGGGGGGGGGGGGPGHE-QELLASPSPHHAGRGAAGSLRGPPPPPTAHQELGTAAAAAA 99
GGGGGGGGGG GGG G+ L++ G G G G TA + LG +A +
Sbjct: 11 GGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRILGGVISAIS 70
Query: 100 AASRSAMVTSMASILDGGDYRPELSIPLHHAMSMSCDSS 138
A+ Y PE P H ++ + S
Sbjct: 71 EAA--------------AQYNPEPPPPRTHYSNIEANES 95
Score = 35.0 bits (79), Expect = 0.16
Identities = 18/36 (50%), Positives = 18/36 (50%), Gaps = 16/36 (44%)
Query: 37 GGGSGGGGGGG----------------GGGGGGGPG 56
GGG GGGGGGG GGGGGGG G
Sbjct: 10 GGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGG 45
>gi|51599151 calpain, small subunit 1 [Homo sapiens]
Length = 268
Score = 57.8 bits (138), Expect = 2e-08
Identities = 31/60 (51%), Positives = 32/60 (53%), Gaps = 2/60 (3%)
Query: 29 LGTLHGPAGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPPPPTAH 88
LG L AGGG GGGGGGGGGGGGGG G +L A AA PPPP H
Sbjct: 29 LGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRILGGVI--SAISEAAAQYNPEPPPPRTH 86
Score = 38.9 bits (89), Expect = 0.011
Identities = 31/99 (31%), Positives = 41/99 (41%), Gaps = 15/99 (15%)
Query: 41 GGGGGGGGGGGGGGPGHE-QELLASPSPHHAGRGAAGSLRGPPPPPTAHQELGTAAAAAA 99
GGGGGGGGGG GGG G+ L++ G G G G TA + LG +A +
Sbjct: 11 GGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGGGGGGGGGGGGGTAMRILGGVISAIS 70
Query: 100 AASRSAMVTSMASILDGGDYRPELSIPLHHAMSMSCDSS 138
A+ Y PE P H ++ + S
Sbjct: 71 EAA--------------AQYNPEPPPPRTHYSNIEANES 95
Score = 35.0 bits (79), Expect = 0.16
Identities = 18/36 (50%), Positives = 18/36 (50%), Gaps = 16/36 (44%)
Query: 37 GGGSGGGGGGG----------------GGGGGGGPG 56
GGG GGGGGGG GGGGGGG G
Sbjct: 10 GGGGGGGGGGGLGGGLGNVLGGLISGAGGGGGGGGG 45
>gi|20070107 orthodenticle homeobox 1 [Homo sapiens]
Length = 354
Score = 57.8 bits (138), Expect = 2e-08
Identities = 46/170 (27%), Positives = 59/170 (34%), Gaps = 15/170 (8%)
Query: 36 AGGGSGGGGGGGGGGGGGGPGHEQELLASP------SPHHAGRGAAGSLRGPPPPPTAHQ 89
A S G GG P L++P SP G+A + P P A
Sbjct: 142 ASSSSANPAAAAAAGLGGNPVAAASSLSTPAASSIWSPASISPGSAPASVSVPEPLAAPS 201
Query: 90 ELGTAAAAAAAASRSAMVTSMASILDGGDYRPELSIPLHHAMS-MSCDSSPPGMGMSNTY 148
+ AA + +A + S GG Y P + C S M +++
Sbjct: 202 NTSCMQRSVAAGAATAAASYPMSYGQGGSYGQGYPTPSSSYFGGVDCSSYLAPM---HSH 258
Query: 149 TTLTPLQPLPPISTVSDKFHHPHPHH-----HPHHHHHHHHQRLSGNVSG 193
L P+ P S HHPH HH HHHHHHHH SG
Sbjct: 259 HHPHQLSPMAPSSMAGHHHHHPHAHHPLSQSSGHHHHHHHHHHQGYGGSG 308
Score = 30.0 bits (66), Expect = 5.1
Identities = 25/104 (24%), Positives = 46/104 (44%), Gaps = 4/104 (3%)
Query: 391 MWKWLQEPEFQRMSALRLAACKRKEQEPNKD---RNNSQKKSRLVFTDLQRRTLFAIFKE 447
M +L++P + M+ L LA P+ Q++ R FT Q L A+F +
Sbjct: 1 MMSYLKQPPYG-MNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAK 59
Query: 448 NKRPSKEMQITISQQLGLELTTVSNFFMNARRRSLEKWQDDLST 491
+ P M+ ++ ++ L + V +F N R + ++ Q T
Sbjct: 60 TRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSGSGT 103
>gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding
protein homolog 1 [Homo sapiens]
Length = 557
Score = 55.5 bits (132), Expect = 1e-07
Identities = 26/37 (70%), Positives = 26/37 (70%), Gaps = 6/37 (16%)
Query: 30 GTLHGPAGGGSG------GGGGGGGGGGGGGPGHEQE 60
G L G GGG G GGGGGGGGGGGGGPGHEQE
Sbjct: 60 GLLCGETGGGGGSALGPGGGGGGGGGGGGGGPGHEQE 96
>gi|21322252 androgen receptor isoform 1 [Homo sapiens]
Length = 920
Score = 54.7 bits (130), Expect = 2e-07
Identities = 22/27 (81%), Positives = 23/27 (85%)
Query: 30 GTLHGPAGGGSGGGGGGGGGGGGGGPG 56
G L+GP GGG GGGGGGGGGGGGGG G
Sbjct: 444 GQLYGPCGGGGGGGGGGGGGGGGGGGG 470
>gi|6912752 zinc finger protein 281 [Homo sapiens]
Length = 895
Score = 54.3 bits (129), Expect = 3e-07
Identities = 43/151 (28%), Positives = 59/151 (39%), Gaps = 16/151 (10%)
Query: 34 GPAGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPPPPTAHQELGT 93
G +GG GGGG GGGGGGG G E+ P + R PP T
Sbjct: 15 GSSGGSGSGGGGSGGGGGGGSSGRRAEM----EPTFPQGMVMFNHRLPPVTSF------T 64
Query: 94 AAAAAAAASRSAMVTSMASILDGGDYRPELSIPLHHAMSMSCDSSPPGMGMSNTYTTLTP 153
A +AA +++S S + P P M+ + + + T+
Sbjct: 65 RPAGSAAPPPQCVLSSSTSAAPAAEPPP----PPAPDMTFKKEPAASAAAFPSQRTSWGF 120
Query: 154 LQPLPPISTVSDKFHHPHPHHHPHHHHHHHH 184
LQ L +S +K P HHHHHHH+
Sbjct: 121 LQSL--VSIKQEKPADPEEQQSHHHHHHHHY 149
>gi|41281831 neuronal PAS domain protein 3 isoform 2 [Homo sapiens]
Length = 920
Score = 52.4 bits (124), Expect = 1e-06
Identities = 45/145 (31%), Positives = 61/145 (42%), Gaps = 39/145 (26%)
Query: 38 GGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPPPPTAHQELGTAAAA 97
G GGGGGGGGG GGGGP LL + R AG++ P H+ GT AA
Sbjct: 748 GNGGGGGGGGGGAGGGGPSASNSLLYTGDLEALQRLQAGNV----VLPLVHRVTGTLAAT 803
Query: 98 AAAASR-----------SAMVTSMASILDGGDYRPELSIPLHHAMSMSCDSSPPGMGMSN 146
+ AA R + + +M S L +P HA++ D + PG G+
Sbjct: 804 STAAQRVYTTGTIRYAPAEVTLAMQSNL----------LPNAHAVNF-VDVNSPGFGLD- 851
Query: 147 TYTTLTPLQPLPPISTVSDKFHHPH 171
TP++ L +HH H
Sbjct: 852 ---PKTPMEML---------YHHVH 864
Score = 31.2 bits (69), Expect = 2.3
Identities = 12/17 (70%), Positives = 13/17 (76%)
Query: 33 HGPAGGGSGGGGGGGGG 49
H P+ G GGGGGGGGG
Sbjct: 677 HFPSPQGGGGGGGGGGG 693
Score = 30.0 bits (66), Expect = 5.1
Identities = 11/11 (100%), Positives = 11/11 (100%)
Query: 41 GGGGGGGGGGG 51
GGGGGGGGGGG
Sbjct: 683 GGGGGGGGGGG 693
Score = 30.0 bits (66), Expect = 5.1
Identities = 11/11 (100%), Positives = 11/11 (100%)
Query: 42 GGGGGGGGGGG 52
GGGGGGGGGGG
Sbjct: 683 GGGGGGGGGGG 693
Score = 30.0 bits (66), Expect = 5.1
Identities = 11/11 (100%), Positives = 11/11 (100%)
Query: 43 GGGGGGGGGGG 53
GGGGGGGGGGG
Sbjct: 683 GGGGGGGGGGG 693
Score = 30.0 bits (66), Expect = 5.1
Identities = 11/11 (100%), Positives = 11/11 (100%)
Query: 44 GGGGGGGGGGG 54
GGGGGGGGGGG
Sbjct: 683 GGGGGGGGGGG 693
>gi|11545847 neuronal PAS domain protein 3 isoform 1 [Homo sapiens]
Length = 901
Score = 52.4 bits (124), Expect = 1e-06
Identities = 45/145 (31%), Positives = 61/145 (42%), Gaps = 39/145 (26%)
Query: 38 GGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPPPPTAHQELGTAAAA 97
G GGGGGGGGG GGGGP LL + R AG++ P H+ GT AA
Sbjct: 729 GNGGGGGGGGGGAGGGGPSASNSLLYTGDLEALQRLQAGNV----VLPLVHRVTGTLAAT 784
Query: 98 AAAASR-----------SAMVTSMASILDGGDYRPELSIPLHHAMSMSCDSSPPGMGMSN 146
+ AA R + + +M S L +P HA++ D + PG G+
Sbjct: 785 STAAQRVYTTGTIRYAPAEVTLAMQSNL----------LPNAHAVNF-VDVNSPGFGLD- 832
Query: 147 TYTTLTPLQPLPPISTVSDKFHHPH 171
TP++ L +HH H
Sbjct: 833 ---PKTPMEML---------YHHVH 845
Score = 31.2 bits (69), Expect = 2.3
Identities = 12/17 (70%), Positives = 13/17 (76%)
Query: 33 HGPAGGGSGGGGGGGGG 49
H P+ G GGGGGGGGG
Sbjct: 658 HFPSPQGGGGGGGGGGG 674
Score = 30.0 bits (66), Expect = 5.1
Identities = 11/11 (100%), Positives = 11/11 (100%)
Query: 41 GGGGGGGGGGG 51
GGGGGGGGGGG
Sbjct: 664 GGGGGGGGGGG 674
Score = 30.0 bits (66), Expect = 5.1
Identities = 11/11 (100%), Positives = 11/11 (100%)
Query: 42 GGGGGGGGGGG 52
GGGGGGGGGGG
Sbjct: 664 GGGGGGGGGGG 674
Score = 30.0 bits (66), Expect = 5.1
Identities = 11/11 (100%), Positives = 11/11 (100%)
Query: 43 GGGGGGGGGGG 53
GGGGGGGGGGG
Sbjct: 664 GGGGGGGGGGG 674
Score = 30.0 bits (66), Expect = 5.1
Identities = 11/11 (100%), Positives = 11/11 (100%)
Query: 44 GGGGGGGGGGG 54
GGGGGGGGGGG
Sbjct: 664 GGGGGGGGGGG 674
>gi|89145413 short stature homeobox 2 isoform a [Homo sapiens]
Length = 331
Score = 52.0 bits (123), Expect = 1e-06
Identities = 44/135 (32%), Positives = 56/135 (41%), Gaps = 28/135 (20%)
Query: 36 AGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPPPPTAHQELGTAA 95
AGGG GGGGGGGGGGGGGG G G GA G G P +EL A
Sbjct: 59 AGGGGGGGGGGGGGGGGGGVG--------------GGGAGGGAGGGRSPV---RELDMGA 101
Query: 96 AAAAAASRSAMVTSMASILDGGDYRPELSIPLHHAMSMSCDSSPPGMGMSNTYTTLTPLQ 155
A + S +T ++ PEL A M D + + T T L+
Sbjct: 102 AERSREPGSPRLTEVS---------PELKDRKEDAKGME-DEGQTKIKQRRSRTNFT-LE 150
Query: 156 PLPPISTVSDKFHHP 170
L + + D+ H+P
Sbjct: 151 QLNELERLFDETHYP 165
Score = 38.9 bits (89), Expect = 0.011
Identities = 35/116 (30%), Positives = 50/116 (43%), Gaps = 8/116 (6%)
Query: 396 QEPEFQRMSALRLAACKRKEQ----EPNKDRNNSQKKSRLVFTDLQRRTLFAIFKENKRP 451
+EP R++ + RKE E Q++SR FT Q L +F E P
Sbjct: 106 REPGSPRLTEVSPELKDRKEDAKGMEDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYP 165
Query: 452 SKEMQITISQQLGLELTTVSNFFMNARRRSLEKWQDDLSTG---GSSSTSSTCTKA 504
M+ +SQ+LGL V +F N RR K ++ L G G++S C A
Sbjct: 166 DAFMREELSQRLGLSEARVQVWFQN-RRAKCRKQENQLHKGVLIGAASQFEACRVA 220
>gi|55770830 chromobox homolog 4 [Homo sapiens]
Length = 560
Score = 52.0 bits (123), Expect = 1e-06
Identities = 22/45 (48%), Positives = 24/45 (53%), Gaps = 1/45 (2%)
Query: 149 TTLTPLQPLPPISTVSDKFHHPHPH-HHPHHHHHHHHQRLSGNVS 192
TT L P HHPHPH HH HHHHHHHH + N+S
Sbjct: 363 TTKPDLLAWDPARNTHPPSHHPHPHPHHHHHHHHHHHHAVGLNLS 407
>gi|210147522 zinc finger, SWIM-type containing 6 [Homo sapiens]
Length = 1215
Score = 52.0 bits (123), Expect = 1e-06
Identities = 38/111 (34%), Positives = 45/111 (40%), Gaps = 17/111 (15%)
Query: 23 ELTMESLGTLHGPAGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPP 82
E+ M S G A GG G GGGGG GGGG G A+ S AA +
Sbjct: 120 EICMYSSFNTGGGAAGGPGDDSGGGGGAGGGGGGGSSSSPAATSAAATSAAAAAA----- 174
Query: 83 PPPTAHQELGTAAAAAAAASRSAMVTSMASILDGGDYRPELSIPLHHAMSM 133
AAAAAAAA A A DGGD E +P +++
Sbjct: 175 ---------AAAAAAAAAAGAGAPSVGAAGAADGGD---ETRLPFRRGIAL 213
Score = 43.5 bits (101), Expect = 4e-04
Identities = 28/75 (37%), Positives = 30/75 (40%), Gaps = 10/75 (13%)
Query: 35 PAGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGP------PPPPTAH 88
P GGG GGG GGGGG GGG P P G AA + G PP T
Sbjct: 18 PGGGGGGGGSSGGGGGAGGG----YSSACRPGPRAGGAAAAAACGGGAALGLLPPGKTQS 73
Query: 89 QELGTAAAAAAAASR 103
E AA A +
Sbjct: 74 PESLLDIAARRVAEK 88
>gi|18375613 dachshund homolog 1 isoform b [Homo sapiens]
Length = 558
Score = 51.6 bits (122), Expect = 2e-06
Identities = 29/84 (34%), Positives = 45/84 (53%), Gaps = 5/84 (5%)
Query: 34 GPAGGGSGGGGG-----GGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPPPPTAH 88
G GGGSGGGGG GGGGGGGGG L A+ + G G + G +
Sbjct: 76 GGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPIN 135
Query: 89 QELGTAAAAAAAASRSAMVTSMAS 112
G+++++++++S S+ +S +S
Sbjct: 136 ASTGSSSSSSSSSSSSSSSSSSSS 159
Score = 37.0 bits (84), Expect = 0.042
Identities = 33/132 (25%), Positives = 49/132 (37%), Gaps = 6/132 (4%)
Query: 27 ESLGTLHGPAGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPPPPT 86
E + + A + GGGGGGGG GGG G +S + G G GS P
Sbjct: 58 EPIASAAAAAATVTSTGGGGGGGGSGGGGG------SSGNGGGGGGGGGGSNCNPNLAAA 111
Query: 87 AHQELGTAAAAAAAASRSAMVTSMASILDGGDYRPELSIPLHHAMSMSCDSSPPGMGMSN 146
++ G +A ++ AS S + S S SS +
Sbjct: 112 SNGSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSSCGPLPGKP 171
Query: 147 TYTTLTPLQPLP 158
Y+T +P++ P
Sbjct: 172 VYSTPSPVENTP 183
Score = 32.0 bits (71), Expect = 1.4
Identities = 22/61 (36%), Positives = 27/61 (44%), Gaps = 18/61 (29%)
Query: 17 GCAMNPELTMESLGTLHGPAGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAG 76
G NP L A GSGGGGGG GGG +AS +P +A G++
Sbjct: 101 GSNCNPNLAA---------ASNGSGGGGGGISAGGG---------VASSTPINASTGSSS 142
Query: 77 S 77
S
Sbjct: 143 S 143
>gi|18375611 dachshund homolog 1 isoform a [Homo sapiens]
Length = 706
Score = 51.6 bits (122), Expect = 2e-06
Identities = 29/84 (34%), Positives = 45/84 (53%), Gaps = 5/84 (5%)
Query: 34 GPAGGGSGGGGG-----GGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPPPPTAH 88
G GGGSGGGGG GGGGGGGGG L A+ + G G + G +
Sbjct: 76 GGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPIN 135
Query: 89 QELGTAAAAAAAASRSAMVTSMAS 112
G+++++++++S S+ +S +S
Sbjct: 136 ASTGSSSSSSSSSSSSSSSSSSSS 159
Score = 37.0 bits (84), Expect = 0.042
Identities = 33/132 (25%), Positives = 49/132 (37%), Gaps = 6/132 (4%)
Query: 27 ESLGTLHGPAGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPPPPT 86
E + + A + GGGGGGGG GGG G +S + G G GS P
Sbjct: 58 EPIASAAAAAATVTSTGGGGGGGGSGGGGG------SSGNGGGGGGGGGGSNCNPNLAAA 111
Query: 87 AHQELGTAAAAAAAASRSAMVTSMASILDGGDYRPELSIPLHHAMSMSCDSSPPGMGMSN 146
++ G +A ++ AS S + S S SS +
Sbjct: 112 SNGSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSSCGPLPGKP 171
Query: 147 TYTTLTPLQPLP 158
Y+T +P++ P
Sbjct: 172 VYSTPSPVENTP 183
Score = 32.0 bits (71), Expect = 1.4
Identities = 22/61 (36%), Positives = 27/61 (44%), Gaps = 18/61 (29%)
Query: 17 GCAMNPELTMESLGTLHGPAGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAG 76
G NP L A GSGGGGGG GGG +AS +P +A G++
Sbjct: 101 GSNCNPNLAA---------ASNGSGGGGGGISAGGG---------VASSTPINASTGSSS 142
Query: 77 S 77
S
Sbjct: 143 S 143
>gi|18375609 dachshund homolog 1 isoform c [Homo sapiens]
Length = 504
Score = 51.6 bits (122), Expect = 2e-06
Identities = 29/84 (34%), Positives = 45/84 (53%), Gaps = 5/84 (5%)
Query: 34 GPAGGGSGGGGG-----GGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPPPPTAH 88
G GGGSGGGGG GGGGGGGGG L A+ + G G + G +
Sbjct: 76 GGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVASSTPIN 135
Query: 89 QELGTAAAAAAAASRSAMVTSMAS 112
G+++++++++S S+ +S +S
Sbjct: 136 ASTGSSSSSSSSSSSSSSSSSSSS 159
Score = 37.0 bits (84), Expect = 0.042
Identities = 33/132 (25%), Positives = 49/132 (37%), Gaps = 6/132 (4%)
Query: 27 ESLGTLHGPAGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPPPPT 86
E + + A + GGGGGGGG GGG G +S + G G GS P
Sbjct: 58 EPIASAAAAAATVTSTGGGGGGGGSGGGGG------SSGNGGGGGGGGGGSNCNPNLAAA 111
Query: 87 AHQELGTAAAAAAAASRSAMVTSMASILDGGDYRPELSIPLHHAMSMSCDSSPPGMGMSN 146
++ G +A ++ AS S + S S SS +
Sbjct: 112 SNGSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSSCGPLPGKP 171
Query: 147 TYTTLTPLQPLP 158
Y+T +P++ P
Sbjct: 172 VYSTPSPVENTP 183
Score = 32.0 bits (71), Expect = 1.4
Identities = 22/61 (36%), Positives = 27/61 (44%), Gaps = 18/61 (29%)
Query: 17 GCAMNPELTMESLGTLHGPAGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAG 76
G NP L A GSGGGGGG GGG +AS +P +A G++
Sbjct: 101 GSNCNPNLAA---------ASNGSGGGGGGISAGGG---------VASSTPINASTGSSS 142
Query: 77 S 77
S
Sbjct: 143 S 143
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 51.6 bits (122), Expect = 2e-06
Identities = 42/154 (27%), Positives = 62/154 (40%), Gaps = 18/154 (11%)
Query: 47 GGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPPPPTAHQELGTAAAAAAAASRSAM 106
G G GG PG E+ +PSPH ++ + P PP +++++AAA+S S+
Sbjct: 336 GQGMGGLPPGPEKGPTLAPSPHSLPPASSSA----PAPPMRFPYSSSSSSSAAASSSSSS 391
Query: 107 VTSMASILDGGDYRPELSIPLHHAMSMSCDSSPPGMGM----SNTYTTLTPLQPLPPIST 162
+S AS P S+S + PP S + P P P
Sbjct: 392 SSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRL 451
Query: 163 VSDKFHHPHPH----------HHPHHHHHHHHQR 186
+++ HP P H P HHHHHQ+
Sbjct: 452 LANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQ 485
Score = 43.5 bits (101), Expect = 4e-04
Identities = 81/303 (26%), Positives = 106/303 (34%), Gaps = 63/303 (20%)
Query: 30 GTLHGPAGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPP--PPTA 87
G L GP G GGG GG GG H P P ++ G PP PPT
Sbjct: 226 GVLSGPPMGPKGGGAASSVGGPNGGKQH-------PPPTTPISVSSSGASGAPPTKPPTT 278
Query: 88 HQELGTAAAAAAAASRSAMVTSMASILDGGDYRPELSIPLHHAMSMSCDSSPPGMGMSNT 147
G +A A+ + ++ P PL++A +SPPG+G
Sbjct: 279 PVGGGNLPSAPPPANFPHVTPNLPP--------PPALRPLNNA-----SASPPGLG---- 321
Query: 148 YTTLTPLQPLPPISTVSDKFHHPHPHHHPHHHHHHHHQRLSGNVSG---SFTLMRDERGL 204
QPLP H P P H Q + G G TL L
Sbjct: 322 ------AQPLPG--------HLPSP--------HAMGQGMGGLPPGPEKGPTLAPSPHSL 359
Query: 205 -PAMNNLYSPYKEMPGMSQSLSPLAATPLGNGLGGLHN---AQQSLPNYG---PPGHDKM 257
PA ++ +P P S S S AA+ + + A Q+LP+Y PP
Sbjct: 360 PPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLS 419
Query: 258 LSPNFDAHHTAMLTRGEQHLSRGLGTPPAAMMSHLNGLHHPG-HTQSHGPVLAPSRERPP 316
+S N +T + S+G PP N HPG S G A S PP
Sbjct: 420 VS-NQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTG---AQSTAHPP 475
Query: 317 SSS 319
S+
Sbjct: 476 VST 478
Score = 30.8 bits (68), Expect = 3.0
Identities = 29/99 (29%), Positives = 37/99 (37%), Gaps = 19/99 (19%)
Query: 230 TPLGNGLGGLHNAQQSLPNYGPPGHDKMLSPNFDAHHTAMLTRGEQHLSRGLGTPPAAMM 289
TP+G G +LP+ PP + ++PN GLG P +
Sbjct: 278 TPVGGG---------NLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQP--LP 326
Query: 290 SHLNGLHHPGHTQS-------HGPVLAPS-RERPPSSSS 320
HL H G GP LAPS PP+SSS
Sbjct: 327 GHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSS 365
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 51.6 bits (122), Expect = 2e-06
Identities = 42/154 (27%), Positives = 62/154 (40%), Gaps = 18/154 (11%)
Query: 47 GGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPPPPTAHQELGTAAAAAAAASRSAM 106
G G GG PG E+ +PSPH ++ + P PP +++++AAA+S S+
Sbjct: 336 GQGMGGLPPGPEKGPTLAPSPHSLPPASSSA----PAPPMRFPYSSSSSSSAAASSSSSS 391
Query: 107 VTSMASILDGGDYRPELSIPLHHAMSMSCDSSPPGMGM----SNTYTTLTPLQPLPPIST 162
+S AS P S+S + PP S + P P P
Sbjct: 392 SSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRL 451
Query: 163 VSDKFHHPHPH----------HHPHHHHHHHHQR 186
+++ HP P H P HHHHHQ+
Sbjct: 452 LANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQ 485
Score = 43.5 bits (101), Expect = 4e-04
Identities = 81/303 (26%), Positives = 106/303 (34%), Gaps = 63/303 (20%)
Query: 30 GTLHGPAGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPP--PPTA 87
G L GP G GGG GG GG H P P ++ G PP PPT
Sbjct: 226 GVLSGPPMGPKGGGAASSVGGPNGGKQH-------PPPTTPISVSSSGASGAPPTKPPTT 278
Query: 88 HQELGTAAAAAAAASRSAMVTSMASILDGGDYRPELSIPLHHAMSMSCDSSPPGMGMSNT 147
G +A A+ + ++ P PL++A +SPPG+G
Sbjct: 279 PVGGGNLPSAPPPANFPHVTPNLPP--------PPALRPLNNA-----SASPPGLG---- 321
Query: 148 YTTLTPLQPLPPISTVSDKFHHPHPHHHPHHHHHHHHQRLSGNVSG---SFTLMRDERGL 204
QPLP H P P H Q + G G TL L
Sbjct: 322 ------AQPLPG--------HLPSP--------HAMGQGMGGLPPGPEKGPTLAPSPHSL 359
Query: 205 -PAMNNLYSPYKEMPGMSQSLSPLAATPLGNGLGGLHN---AQQSLPNYG---PPGHDKM 257
PA ++ +P P S S S AA+ + + A Q+LP+Y PP
Sbjct: 360 PPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLS 419
Query: 258 LSPNFDAHHTAMLTRGEQHLSRGLGTPPAAMMSHLNGLHHPG-HTQSHGPVLAPSRERPP 316
+S N +T + S+G PP N HPG S G A S PP
Sbjct: 420 VS-NQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTG---AQSTAHPP 475
Query: 317 SSS 319
S+
Sbjct: 476 VST 478
Score = 30.8 bits (68), Expect = 3.0
Identities = 29/99 (29%), Positives = 37/99 (37%), Gaps = 19/99 (19%)
Query: 230 TPLGNGLGGLHNAQQSLPNYGPPGHDKMLSPNFDAHHTAMLTRGEQHLSRGLGTPPAAMM 289
TP+G G +LP+ PP + ++PN GLG P +
Sbjct: 278 TPVGGG---------NLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQP--LP 326
Query: 290 SHLNGLHHPGHTQS-------HGPVLAPS-RERPPSSSS 320
HL H G GP LAPS PP+SSS
Sbjct: 327 GHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSS 365
>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
Length = 3703
Score = 51.6 bits (122), Expect = 2e-06
Identities = 23/35 (65%), Positives = 23/35 (65%)
Query: 32 LHGPAGGGSGGGGGGGGGGGGGGPGHEQELLASPS 66
LH P GGG GG GGGGGGGGGGG G LA S
Sbjct: 3502 LHVPTGGGGGGSGGGGGGGGGGGGGGSYHCLACES 3536
Score = 30.8 bits (68), Expect = 3.0
Identities = 18/65 (27%), Positives = 32/65 (49%), Gaps = 5/65 (7%)
Query: 416 QEPNKDRNNSQKKSRLVFTDLQRRTLFAIFKENKRPSKEMQITISQQLGLELTTVSNFFM 475
+EP +D K+ R T Q L+ + + P+++M I+ ++GL+ V +F
Sbjct: 2636 EEPQRD-----KRLRTTITPEQLEILYQKYLLDSNPTRKMLDHIAHEVGLKKRVVQVWFQ 2690
Query: 476 NARRR 480
N R R
Sbjct: 2691 NTRAR 2695
Score = 29.6 bits (65), Expect = 6.7
Identities = 16/55 (29%), Positives = 27/55 (49%)
Query: 426 QKKSRLVFTDLQRRTLFAIFKENKRPSKEMQITISQQLGLELTTVSNFFMNARRR 480
QK+ R T+LQ + L + F + + P+ + +GL V +F NAR +
Sbjct: 2946 QKRFRTQMTNLQLKVLKSCFNDYRTPTMLECEVLGNDIGLPKRVVQVWFQNARAK 3000
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,325,284
Number of Sequences: 37866
Number of extensions: 1451261
Number of successful extensions: 31488
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 732
Number of HSP's successfully gapped in prelim test: 451
Number of HSP's that attempted gapping in prelim test: 12350
Number of HSP's gapped (non-prelim): 8758
length of query: 504
length of database: 18,247,518
effective HSP length: 107
effective length of query: 397
effective length of database: 14,195,856
effective search space: 5635754832
effective search space used: 5635754832
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.