Guide to the Human Genome
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Search of human proteins with 239752764

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239752764 PREDICTED: hypothetical protein [Homo sapiens]
         (370 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239752764 PREDICTED: hypothetical protein [Homo sapiens]           761   0.0  
gi|239747300 PREDICTED: hypothetical protein XP_002346414 [Homo ...   480   e-135
gi|239741124 PREDICTED: hypothetical protein XP_002342114 [Homo ...   480   e-135
gi|78042577 MAP7 domain containing 1 [Homo sapiens]                    57   3e-08
gi|169206489 PREDICTED: hypothetical protein [Homo sapiens]            56   5e-08
gi|169205942 PREDICTED: hypothetical protein [Homo sapiens]            56   5e-08
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    56   5e-08
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       54   2e-07
gi|19924097 synapsin I isoform Ib [Homo sapiens]                       54   2e-07
gi|33286436 gametogenetin [Homo sapiens]                               54   2e-07
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    54   3e-07
gi|60460889 Myb protein P42POP [Homo sapiens]                          53   5e-07
gi|163965366 nascent polypeptide-associated complex alpha subuni...    51   1e-06
gi|77681565 NG5 protein [Homo sapiens]                                 51   2e-06
gi|169160903 PREDICTED: hypothetical protein [Homo sapiens]            50   2e-06
gi|239745807 PREDICTED: keratin associated protein 4-9 [Homo sap...    50   3e-06
gi|238624195 hypothetical protein LOC221545 isoform 3 [Homo sapi...    50   3e-06
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]         50   4e-06
gi|150170670 piccolo isoform 2 [Homo sapiens]                          49   6e-06
gi|150378539 piccolo isoform 1 [Homo sapiens]                          49   6e-06
gi|119829187 alpha 1 type XVII collagen [Homo sapiens]                 49   7e-06
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    49   7e-06
gi|157785645 SPEG complex locus [Homo sapiens]                         49   7e-06
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        49   9e-06
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 49   9e-06
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     49   9e-06
gi|223972704 hypothetical protein LOC284418 [Homo sapiens]             48   1e-05
gi|169167057 PREDICTED: hypothetical protein [Homo sapiens]            48   1e-05
gi|160707881 formin 2 [Homo sapiens]                                   48   1e-05
gi|47132519 Ras association and pleckstrin homology domains 1 is...    48   1e-05

>gi|239752764 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 370

 Score =  761 bits (1965), Expect = 0.0
 Identities = 370/370 (100%), Positives = 370/370 (100%)

Query: 1   MMLAENRKACSSAFMTWALGPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTR 60
           MMLAENRKACSSAFMTWALGPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTR
Sbjct: 1   MMLAENRKACSSAFMTWALGPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTR 60

Query: 61  LRRRRQGAVIVGRRRACPGRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPR 120
           LRRRRQGAVIVGRRRACPGRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPR
Sbjct: 61  LRRRRQGAVIVGRRRACPGRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPR 120

Query: 121 RRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAG 180
           RRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAG
Sbjct: 121 RRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAG 180

Query: 181 LWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPS 240
           LWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPS
Sbjct: 181 LWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPS 240

Query: 241 AHSPAHTHFTLTLAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAPVP 300
           AHSPAHTHFTLTLAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAPVP
Sbjct: 241 AHSPAHTHFTLTLAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAPVP 300

Query: 301 STARARSPGARRGARELAPRAGRRRQPSGRTSWRRRARREQRDREPAVCGAWPRGSHAAG 360
           STARARSPGARRGARELAPRAGRRRQPSGRTSWRRRARREQRDREPAVCGAWPRGSHAAG
Sbjct: 301 STARARSPGARRGARELAPRAGRRRQPSGRTSWRRRARREQRDREPAVCGAWPRGSHAAG 360

Query: 361 AGWTAVAAGD 370
           AGWTAVAAGD
Sbjct: 361 AGWTAVAAGD 370


>gi|239747300 PREDICTED: hypothetical protein XP_002346414 [Homo
           sapiens]
          Length = 470

 Score =  480 bits (1235), Expect = e-135
 Identities = 261/367 (71%), Positives = 264/367 (71%), Gaps = 47/367 (12%)

Query: 1   MMLAENRKACSSAFMTWALGPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTR 60
           MMLAENRKACSSAFMTWALGPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTR
Sbjct: 1   MMLAENRKACSSAFMTWALGPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTR 60

Query: 61  LRRRRQGAVIVGRRRACPGRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPR 120
           LRRRRQGAVIVGRRRACPGRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPR
Sbjct: 61  LRRRRQGAVIVGRRRACPGRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPR 120

Query: 121 RRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAG 180
           RRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAG
Sbjct: 121 RRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAG 180

Query: 181 LWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPS 240
           LWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHAR                         
Sbjct: 181 LWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHAR------------------------- 215

Query: 241 AHSPAHTHFTLTLAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAPVP 300
           AHS AHT                  GGGEGDPGPIVGGRPENEDS      P  P  P P
Sbjct: 216 AHSRAHT----------------CAGGGEGDPGPIVGGRPENEDSPRFPDVPTRPAGPSP 259

Query: 301 STARARSPG-----ARRGARELAPRAGRRRQPSGRTSWRRRARREQRDREPAVCGAWPRG 355
                  PG     AR G       A +R      T     AR   R R  ++    PRG
Sbjct: 260 FYCEGTEPGSQAWSARAGTASWETAAAQRPDQLEETRPPGAARPGAR-RLRSLASRLPRG 318

Query: 356 SHAAGAG 362
                 G
Sbjct: 319 GRWLDGG 325


>gi|239741124 PREDICTED: hypothetical protein XP_002342114 [Homo
           sapiens]
          Length = 470

 Score =  480 bits (1235), Expect = e-135
 Identities = 261/367 (71%), Positives = 264/367 (71%), Gaps = 47/367 (12%)

Query: 1   MMLAENRKACSSAFMTWALGPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTR 60
           MMLAENRKACSSAFMTWALGPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTR
Sbjct: 1   MMLAENRKACSSAFMTWALGPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTR 60

Query: 61  LRRRRQGAVIVGRRRACPGRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPR 120
           LRRRRQGAVIVGRRRACPGRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPR
Sbjct: 61  LRRRRQGAVIVGRRRACPGRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPR 120

Query: 121 RRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAG 180
           RRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAG
Sbjct: 121 RRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAG 180

Query: 181 LWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPS 240
           LWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHAR                         
Sbjct: 181 LWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHAR------------------------- 215

Query: 241 AHSPAHTHFTLTLAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAPVP 300
           AHS AHT                  GGGEGDPGPIVGGRPENEDS      P  P  P P
Sbjct: 216 AHSRAHT----------------CAGGGEGDPGPIVGGRPENEDSPRFPDVPTRPAGPSP 259

Query: 301 STARARSPG-----ARRGARELAPRAGRRRQPSGRTSWRRRARREQRDREPAVCGAWPRG 355
                  PG     AR G       A +R      T     AR   R R  ++    PRG
Sbjct: 260 FYCEGTEPGSQAWSARAGTASWETAAAQRPDQLEETRPPGAARPGAR-RLRSLASRLPRG 318

Query: 356 SHAAGAG 362
                 G
Sbjct: 319 GRWLDGG 325


>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
          Length = 841

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 85/321 (26%), Positives = 108/321 (33%), Gaps = 63/321 (19%)

Query: 75  RAC-PGRGRGGLPGAAALGAGAQQPRRRRLAQPP-----GSRAPLQ-------------V 115
           R C PGRG       A+L  G Q  R    A  P      S +PL               
Sbjct: 326 RGCDPGRGPTWGRAGASLARGPQPDRTHPSAAVPVCPRSASASPLTPCSVTRSVHRCAPA 385

Query: 116 GGAPRRRAHLTGGPP---RRRPPRLAAAHGLPASEAPGLRPDSARTRLRL-RLASARLPR 171
           G    RR    GG P   RRRP     A  +   E      ++ + +  L R  S +  +
Sbjct: 386 GERGERRKPNAGGSPAPVRRRPE----ASPVQKKEKKDKERENEKEKSALARERSLKKRQ 441

Query: 172 GLPPAPAAGLWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPP 231
            LP +P A L  +  + L P     P         SP    H      P+P P   LPP 
Sbjct: 442 SLPASPRARLSASTASELSPKSKARP--------SSPSTSWHRPASPCPSPGPGHTLPPK 493

Query: 232 AP-----------------PAARTPSAHSPAHTHFTLTLAEAHTRALTPARGGGEGDPGP 274
            P                  A  +PSA  P     +   A     +  PA       P P
Sbjct: 494 PPSPRGTTASPKGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSP 553

Query: 275 IVGGRPENED-------SLASQTSPPAPPAPV-PSTARARSPGARRGARELAPRAGRRRQ 326
                P+ E          A  TSPPAP  PV PS   A +       R LA +  + R+
Sbjct: 554 -TPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRRQARE 612

Query: 327 PSGRTSWRRR--ARREQRDRE 345
              R    RR  A R++R RE
Sbjct: 613 QREREEQERRLQAERDKRMRE 633



 Score = 37.0 bits (84), Expect = 0.028
 Identities = 43/159 (27%), Positives = 59/159 (37%), Gaps = 20/159 (12%)

Query: 194 LQPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPAAR----TPSAHSPAHTHF 249
           ++  P    G    P V   ART   P PSP     PP PP +     TP    PA  + 
Sbjct: 1   MESGPRAELGAGAPPAVV--ARTPPEPRPSPEGDPSPPPPPMSALVPDTPPDTPPAMKNA 58

Query: 250 TLTLAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSP--PAPPAPVPSTA---- 303
           T     +    L P    G+  P P     P  E+S +S+     P PPA  P  A    
Sbjct: 59  T----SSKQLPLEPESPSGQVGPRP----APPQEESPSSEAKSRGPTPPAMGPRDARPPR 110

Query: 304 RARSPGARRGARELAPRAGRRRQPSGRTSWRRRARREQR 342
           R+  P         +P   +  + +G      + RRE+R
Sbjct: 111 RSSQPSPTAVPASDSPPTKQEVKKAGERHKLAKERREER 149


>gi|169206489 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 564

 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 99/376 (26%), Positives = 127/376 (33%), Gaps = 74/376 (19%)

Query: 48  AHTRSPAQYSQTRLRRRRQGAVIVGRRRACPGRGRG----GLPG---------AAALGAG 94
           A  ++P      +LR+        G  R C G G      G P            A GA 
Sbjct: 178 ARRKTPLSLCPLKLRK--------GSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGAR 229

Query: 95  AQQPRRRRLAQPPGSRAPLQV-GGAPRRRAHLTGGPPRRR---PPRLAAAHGLPASEAPG 150
           AQ     + A P  +  P  V  G    RA   GG  R+R   P   + + G P  E   
Sbjct: 230 AQVRGSEKRACPGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPTGERSS 289

Query: 151 LRP--DSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLL------------QP 196
             P  D ++      L +AR+    PP+ AA  WR G  + +P +L            + 
Sbjct: 290 REPLLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEE 349

Query: 197 PPMLSPGLAQSPGVELHAR---------TLSLPAPSPA-PCLPPP---APPAARTPSAHS 243
            P     L  + G EL AR           +LP PS A P  P P   APPA        
Sbjct: 350 DPRSGRALEPAQGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAPPARLRGGGGG 409

Query: 244 PAHTHF------TLTLAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPA 297
              T        +       T AL   RG     P  ++ G P          S PAP +
Sbjct: 410 SGLTQLVGSGRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVPH-----FRPLSSPAPQS 464

Query: 298 PVPSTARARSPGARRGAREL----APRAGRR-----RQPSGRTSW-RRRARREQRDREPA 347
           P P +   R+ G R GA  L    APRA          PS    W  +R        +P 
Sbjct: 465 P-PRSPSVRAFGPRLGAGRLSCPQAPRAAALPGIAVLAPSPAHDWGGQRCEGCGGGSQPF 523

Query: 348 VCGAWPRGSHAAGAGW 363
                 RG   AG  W
Sbjct: 524 AGRRAERGKRGAGVPW 539



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 52/201 (25%), Positives = 62/201 (30%), Gaps = 45/201 (22%)

Query: 11  SSAFMTWALGPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTRLRRRRQGAVI 70
           S A   W LG         +  +R       E   +      PAQ S+   R  R G   
Sbjct: 317 SLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEEDPRSGRALEPAQGSELWARAERHGGSS 376

Query: 71  VGRRRACPGRGRGGLPGAAALGAGAQQPRRRR---------------------------- 102
             R    P R R G P       G+  P R R                            
Sbjct: 377 GARTLPTPSRARPGKPAP----RGSAPPARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHA 432

Query: 103 LAQPPGSRAPLQVG---GAPRRRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTR 159
           LA   GSRAP  VG   G P  R      P  + PPR       P+  A G R  + R  
Sbjct: 433 LATRRGSRAPRPVGVLRGVPHFRP--LSSPAPQSPPR------SPSVRAFGPRLGAGRLS 484

Query: 160 LRLRLASARLP--RGLPPAPA 178
                 +A LP    L P+PA
Sbjct: 485 CPQAPRAAALPGIAVLAPSPA 505


>gi|169205942 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 564

 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 99/376 (26%), Positives = 127/376 (33%), Gaps = 74/376 (19%)

Query: 48  AHTRSPAQYSQTRLRRRRQGAVIVGRRRACPGRGRG----GLPG---------AAALGAG 94
           A  ++P      +LR+        G  R C G G      G P            A GA 
Sbjct: 178 ARRKTPLSLCPLKLRK--------GSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGAR 229

Query: 95  AQQPRRRRLAQPPGSRAPLQV-GGAPRRRAHLTGGPPRRR---PPRLAAAHGLPASEAPG 150
           AQ     + A P  +  P  V  G    RA   GG  R+R   P   + + G P  E   
Sbjct: 230 AQVRGSEKRACPGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPTGERSS 289

Query: 151 LRP--DSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLL------------QP 196
             P  D ++      L +AR+    PP+ AA  WR G  + +P +L            + 
Sbjct: 290 REPLLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEE 349

Query: 197 PPMLSPGLAQSPGVELHAR---------TLSLPAPSPA-PCLPPP---APPAARTPSAHS 243
            P     L  + G EL AR           +LP PS A P  P P   APPA        
Sbjct: 350 DPRSGRALEPAQGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAPPARLRGGGGG 409

Query: 244 PAHTHF------TLTLAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPA 297
              T        +       T AL   RG     P  ++ G P          S PAP +
Sbjct: 410 SGLTQLVGSGRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVPH-----FRPLSSPAPQS 464

Query: 298 PVPSTARARSPGARRGAREL----APRAGRR-----RQPSGRTSW-RRRARREQRDREPA 347
           P P +   R+ G R GA  L    APRA          PS    W  +R        +P 
Sbjct: 465 P-PRSPSVRAFGPRLGAGRLSCPQAPRAAALPGIAVLAPSPAHDWGGQRCEGCGGGSQPF 523

Query: 348 VCGAWPRGSHAAGAGW 363
                 RG   AG  W
Sbjct: 524 AGRRAERGKRGAGVPW 539



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 52/201 (25%), Positives = 62/201 (30%), Gaps = 45/201 (22%)

Query: 11  SSAFMTWALGPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTRLRRRRQGAVI 70
           S A   W LG         +  +R       E   +      PAQ S+   R  R G   
Sbjct: 317 SLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEEDPRSGRALEPAQGSELWARAERHGGSS 376

Query: 71  VGRRRACPGRGRGGLPGAAALGAGAQQPRRRR---------------------------- 102
             R    P R R G P       G+  P R R                            
Sbjct: 377 GARTLPTPSRARPGKPAP----RGSAPPARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHA 432

Query: 103 LAQPPGSRAPLQVG---GAPRRRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTR 159
           LA   GSRAP  VG   G P  R      P  + PPR       P+  A G R  + R  
Sbjct: 433 LATRRGSRAPRPVGVLRGVPHFRP--LSSPAPQSPPR------SPSVRAFGPRLGAGRLS 484

Query: 160 LRLRLASARLP--RGLPPAPA 178
                 +A LP    L P+PA
Sbjct: 485 CPQAPRAAALPGIAVLAPSPA 505


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 67/260 (25%), Positives = 91/260 (35%), Gaps = 58/260 (22%)

Query: 87   GAAALGAGAQQPRRRR-LAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLPA 145
            G   L  G + P     +++P  S AP +    P     L    PR     + +  G P+
Sbjct: 1456 GPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPRAP---VTSGRGPPS 1512

Query: 146  SEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQPPPM------ 199
             + PG+ P S R             R +PP+P +   RA      PLL+ PPP       
Sbjct: 1513 EDGPGVPPPSPR-------------RSVPPSPTSP--RASEENGLPLLVLPPPAPSVDVE 1557

Query: 200  ---------LSPGLAQSPGVELHARTLSLPAPSPAPCLP------PPAPPAARTPSAHSP 244
                     L P L  S   E     L+   P P P  P      PP PP A   +  + 
Sbjct: 1558 DGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTL 1617

Query: 245  AHTHFTLTLAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAPVPSTAR 304
              T  +LT  ++    LT       GDP P                 PPAP AP P+  +
Sbjct: 1618 DSTASSLTSYDSEVATLTQGASAAPGDPHP---------------PGPPAPAAPAPAAPQ 1662

Query: 305  A---RSPGARRGARELAPRA 321
                  PG   G  E+  R+
Sbjct: 1663 PGPDPPPGTDSGIEEVDSRS 1682



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 76/271 (28%), Positives = 90/271 (33%), Gaps = 71/271 (26%)

Query: 79   GRGRGGL-PGAAALGAGAQQPR------RRRLAQPPGSRA-----PLQVGGAPRRRA--- 123
            G G GG   G+ A G G            R L  P   +A     PL +  A R RA   
Sbjct: 1307 GAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKE 1366

Query: 124  HLTGG-----PPRRRPPRLAAA------HGLPASEAPGLR------PDSARTRLRLRLAS 166
               GG     PPR   PR  A       H   A   P LR      PD AR  L  R   
Sbjct: 1367 SSEGGGAPQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGL 1426

Query: 167  ARLPRGLPPAPAAGLWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARTLSLPAPSPAP 226
                + LP +P A          R LL + PP        +PGV      L    P+P P
Sbjct: 1427 GSQEKSLPASPPAAR--------RSLLHRLPPT-------APGVGPLLLQLGTEPPAPHP 1471

Query: 227  CLPPPAPPAARTPSAHSPAHTHFTLTLAEAHTRALTPARGGGEGDPGPIVGGR-PENEDS 285
             +  P   AA       P H  F   L     RA             P+  GR P +ED 
Sbjct: 1472 GVSKPWRSAAPEEPERLPLHVRF---LENCQPRA-------------PVTSGRGPPSEDG 1515

Query: 286  LASQTSPPAPPAPVPSTARARSPGARRGARE 316
                   P  P P P  +   SP + R + E
Sbjct: 1516 -------PGVPPPSPRRSVPPSPTSPRASEE 1539



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 79/297 (26%), Positives = 97/297 (32%), Gaps = 67/297 (22%)

Query: 75   RACPGRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRA------PLQVGGAPRRRAHLTGG 128
            RA    GRG  P     G     PRR     P   RA      PL V   P     +  G
Sbjct: 1501 RAPVTSGRGP-PSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDG 1559

Query: 129  P---PRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAG 185
                    PP L  ++     E+P L P            +  LP   PPA AA      
Sbjct: 1560 EFLFVEPLPPPLEFSNSFEKPESP-LTPGPPHPLPDTPAPATPLPPVPPPAVAAA----- 1613

Query: 186  CTRLRPLLLQPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLP-PPAPPAARTPSAHSP 244
                       PP L    +     +    TL+  A S AP  P PP PPA   P+  +P
Sbjct: 1614 -----------PPTLDSTASSLTSYDSEVATLTQGA-SAAPGDPHPPGPPAPAAPAPAAP 1661

Query: 245  ---------------------AHTHFTLTLAEAHTRALTPARGGGE----GDPGPIVGGR 279
                                 +  H   T++ A T +   A GGG     G  G  V   
Sbjct: 1662 QPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASG 1721

Query: 280  PENEDSLASQ--------TSPPAPPAP----VPSTARARSPGARRGARELAPRAGRR 324
            PE  D+  +         +S P PP P     PS  R R+ GA  G R   P  G R
Sbjct: 1722 PELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRP-GPSGGLR 1777



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 70/253 (27%), Positives = 84/253 (33%), Gaps = 67/253 (26%)

Query: 126  TGGPPRRRPPRLAAA--------HGLPASEAPGLRPDSARTRLRLRLASARLPR----GL 173
            TGG P   PPRLA           G   S  PG    S          S++ P      L
Sbjct: 1028 TGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPALRYFQL 1087

Query: 174  PPAPAAGLW----RAGCTRLRPLLLQPP----PMLSPGLAQSPGVELHARTLSLPAPSPA 225
            PP  A+       R+G  R  PL+ Q      P    GL               PAPSP 
Sbjct: 1088 PPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLP--------------PAPSPT 1133

Query: 226  PCLPPPAPPAARTPS-----------------AHSPAHTHFTLTLAEAHTRALTPARGGG 268
                P  PPA   PS                 + S   +  + T AE  T+   P  GGG
Sbjct: 1134 SPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQP-EPTGGGG 1192

Query: 269  EGDPGPIVGGRPENEDSLASQTSP-PAPPAPVPSTARARSPGARRGAREL-APRAGRRRQ 326
             G   P          S A   SP P  P+PVP+ A    P       +  A   G  R+
Sbjct: 1193 GGGSSP----------SPAPAMSPVPPSPSPVPTPASPSGPATLDFTSQFGAALVGAARR 1242

Query: 327  PSGRTSWRRRARR 339
              G   W+  ARR
Sbjct: 1243 EGG---WQNEARR 1252



 Score = 36.6 bits (83), Expect = 0.037
 Identities = 24/66 (36%), Positives = 30/66 (45%), Gaps = 6/66 (9%)

Query: 272 PGPIVGGRPENEDSLASQTSPPAPPAPVPSTARARSPGARRGARELAPRAGR-----RRQ 326
           PG    G P        Q+ P AP   + S+   RS  + RGAR  +P  GR     +RQ
Sbjct: 454 PGAASSGAPGPTSGSQGQSQPSAPTTKL-SSGTLRSASSPRGARARSPSRGRHPEDAKRQ 512

Query: 327 PSGRTS 332
           P GR S
Sbjct: 513 PRGRPS 518



 Score = 33.9 bits (76), Expect = 0.24
 Identities = 38/130 (29%), Positives = 48/130 (36%), Gaps = 31/130 (23%)

Query: 190 RPLLLQPPPML-----SPGLAQ------SPGVELHARTLSLPAPS---PAPCLPPPAPPA 235
           RP  L P P L     S G A+      +P     +R+LS+P      P P   PP PP 
Sbjct: 874 RPSFLPPGPGLMLRQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPY 933

Query: 236 ARTPSAHSPAHTHFTLTLAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSPPAP 295
           +  P   S                 LTP+  GG  +PG    G P    S AS   P  P
Sbjct: 934 STPPVPSSSGR--------------LTPSPRGGPFNPG---SGGPLPASSPASFDGPSPP 976

Query: 296 PAPVPSTARA 305
              V S  ++
Sbjct: 977 DTRVGSREKS 986



 Score = 33.1 bits (74), Expect = 0.41
 Identities = 55/196 (28%), Positives = 68/196 (34%), Gaps = 28/196 (14%)

Query: 155  SARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQPPPMLSP--GLAQSP---- 208
            SA   LRL  A +    G   A +      G +      L P P++ P  G A  P    
Sbjct: 1294 SAEPYLRLESAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPASPL 1353

Query: 209  GVELHARTLSLPAPSP---APCLPPPAPPAAR------TPSAHSPAHTHFTLTLAEAHTR 259
            G+ L AR  +L   S    AP  PPP PP+ R      TP  HSP H H    L      
Sbjct: 1354 GLALAARERALKESSEGGGAP-QPPPRPPSPRYEAPPPTPHHHSP-HAHHEPVLRLWGAS 1411

Query: 260  ALTPA------RGGGEGDPGPIVGGRPENEDSLASQTSPPAPPA-----PVPSTARARSP 308
               PA      R G       +    P    SL  +  P AP        + +   A  P
Sbjct: 1412 PPDPARRELGYRAGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHP 1471

Query: 309  GARRGARELAPRAGRR 324
            G  +  R  AP    R
Sbjct: 1472 GVSKPWRSAAPEEPER 1487


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 75/249 (30%), Positives = 93/249 (37%), Gaps = 29/249 (11%)

Query: 73  RRRACPGRGRGG---LPGAAALGAGAQQPRRRRLAQ--PPGSRAPLQVGGAPRRRAHLTG 127
           +R A PGRG  G    PGA  LG    Q      AQ  PP    P Q G  P+R+    G
Sbjct: 423 QRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQ----G 478

Query: 128 GPPRRRPPRLAAAH----GLPASEAPGLR---PDSARTRLRLRLASARLPRGLPPAPAAG 180
            P ++RPP     H    G PA      R   P SA  +   + A     +G    P AG
Sbjct: 479 PPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAG 538

Query: 181 LWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPS 240
              A      P   +PP   SP     P       ++S PAP P     PP     + P 
Sbjct: 539 GPGA------PPAARPPASPSPQRQAGPPQATRQTSVSGPAP-PKASGAPPGGQQRQGPP 591

Query: 241 AHSPAHTHFTLTLAEAHTRALT-PARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAPV 299
              P     T   ++A     T P         GP   GRP+ +  LA + S   PP   
Sbjct: 592 QKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQ--LAQKPSQDVPP--- 646

Query: 300 PSTARARSP 308
           P+TA A  P
Sbjct: 647 PATAAAGGP 655



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 54/193 (27%), Positives = 72/193 (37%), Gaps = 48/193 (24%)

Query: 170 PRGLPPAPAAGLWRAGCTRLRPLLLQPPPMLSP---GLAQSPGVELHARTLSLPAPSPAP 226
           P+G PP P  G  R G     PL  +PPP       GL    G  L  R   LP+P+ AP
Sbjct: 463 PQGGPPQPGPGPQRQG----PPLQQRPPPQGQQHLSGLGPPAGSPLPQR---LPSPTSAP 515

Query: 227 CLP---------------------PPAPPAARTPSAHSPAH-------THFTLTLAEAHT 258
             P                     P APPAAR P++ SP         T  T     A  
Sbjct: 516 QQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPP 575

Query: 259 RALTPARGGGEGD------PGPIVGGRPENEDSLASQTSPPAPPAPVPS----TARARSP 308
           +A     GG +        PGP    R  ++     +T PP    P PS      R +  
Sbjct: 576 KASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQ 635

Query: 309 GARRGARELAPRA 321
            A++ ++++ P A
Sbjct: 636 LAQKPSQDVPPPA 648



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 60/219 (27%), Positives = 77/219 (35%), Gaps = 39/219 (17%)

Query: 19  LGPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTRLRRRRQGAVIVGRRRACP 78
           LGP A S +P RLP       P  +  Q A   +P    Q R  R              P
Sbjct: 496 LGPPAGSPLPQRLP------SPTSAPQQPASQAAPPTQGQGRQSR--------------P 535

Query: 79  GRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGG--APRRRAHLTGGPPRRRPPR 136
             G  G P AA   A    P  +R A PP +     V G   P+      GG  R+ PP+
Sbjct: 536 VAGGPGAPPAARPPA---SPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQ 592

Query: 137 LAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQP 196
                  P    P  +   A    R    + + PR   P PA         R +P L Q 
Sbjct: 593 KP-----PGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAG--------RPKPQLAQK 639

Query: 197 PPM-LSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPP 234
           P   + P    + G   H +     + + A  LP PAPP
Sbjct: 640 PSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPEPAPP 678



 Score = 37.7 bits (86), Expect = 0.017
 Identities = 46/166 (27%), Positives = 56/166 (33%), Gaps = 18/166 (10%)

Query: 201 SPGLAQSPG-VELHARTLSLPAPSPAPCLPPPA---PPAARTPSAHSPAHTHFTLTLAEA 256
           S G   SPG + L  +T   PA  PA   PPP    P     P    P          + 
Sbjct: 432 SHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQ 491

Query: 257 HTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAPVPSTARARSPGARRGARE 316
           H   L P  G       P     P+     ASQ +PP       S   A  PGA   AR 
Sbjct: 492 HLSGLGPPAGSPLPQRLPSPTSAPQQP---ASQAAPPTQGQGRQSRPVAGGPGAPPAAR- 547

Query: 317 LAPRAGRRRQPSGRTSWRRRARREQRDREPAVCGAWPRGSHAAGAG 362
                     P    S +R+A   Q  R+ +V G  P  +  A  G
Sbjct: 548 ----------PPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPG 583



 Score = 32.0 bits (71), Expect = 0.91
 Identities = 26/84 (30%), Positives = 31/84 (36%), Gaps = 4/84 (4%)

Query: 230 PPAPPAARTPSAHSPAHTHFTLTLAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQ 289
           PP PP    P AHSP  T    T     +  + PA       PG   GG   +  S A +
Sbjct: 30  PPPPP----PGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGGFFSSLSNAVK 85

Query: 290 TSPPAPPAPVPSTARARSPGARRG 313
            +  A  A         S GA RG
Sbjct: 86  QTTAAAAATFSEQVGGGSGGAGRG 109


>gi|19924097 synapsin I isoform Ib [Homo sapiens]
          Length = 669

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 75/249 (30%), Positives = 93/249 (37%), Gaps = 29/249 (11%)

Query: 73  RRRACPGRGRGG---LPGAAALGAGAQQPRRRRLAQ--PPGSRAPLQVGGAPRRRAHLTG 127
           +R A PGRG  G    PGA  LG    Q      AQ  PP    P Q G  P+R+    G
Sbjct: 423 QRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQ----G 478

Query: 128 GPPRRRPPRLAAAH----GLPASEAPGLR---PDSARTRLRLRLASARLPRGLPPAPAAG 180
            P ++RPP     H    G PA      R   P SA  +   + A     +G    P AG
Sbjct: 479 PPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAG 538

Query: 181 LWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPS 240
              A      P   +PP   SP     P       ++S PAP P     PP     + P 
Sbjct: 539 GPGA------PPAARPPASPSPQRQAGPPQATRQTSVSGPAP-PKASGAPPGGQQRQGPP 591

Query: 241 AHSPAHTHFTLTLAEAHTRALT-PARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAPV 299
              P     T   ++A     T P         GP   GRP+ +  LA + S   PP   
Sbjct: 592 QKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQ--LAQKPSQDVPP--- 646

Query: 300 PSTARARSP 308
           P+TA A  P
Sbjct: 647 PATAAAGGP 655



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 54/193 (27%), Positives = 72/193 (37%), Gaps = 48/193 (24%)

Query: 170 PRGLPPAPAAGLWRAGCTRLRPLLLQPPPMLSP---GLAQSPGVELHARTLSLPAPSPAP 226
           P+G PP P  G  R G     PL  +PPP       GL    G  L  R   LP+P+ AP
Sbjct: 463 PQGGPPQPGPGPQRQG----PPLQQRPPPQGQQHLSGLGPPAGSPLPQR---LPSPTSAP 515

Query: 227 CLP---------------------PPAPPAARTPSAHSPAH-------THFTLTLAEAHT 258
             P                     P APPAAR P++ SP         T  T     A  
Sbjct: 516 QQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPP 575

Query: 259 RALTPARGGGEGD------PGPIVGGRPENEDSLASQTSPPAPPAPVPS----TARARSP 308
           +A     GG +        PGP    R  ++     +T PP    P PS      R +  
Sbjct: 576 KASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQ 635

Query: 309 GARRGARELAPRA 321
            A++ ++++ P A
Sbjct: 636 LAQKPSQDVPPPA 648



 Score = 42.0 bits (97), Expect = 9e-04
 Identities = 60/228 (26%), Positives = 76/228 (33%), Gaps = 56/228 (24%)

Query: 19  LGPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTRLRRRRQGAVIVGRRRACP 78
           LGP A S +P RLP       P  +  Q A   +P    Q R  R              P
Sbjct: 496 LGPPAGSPLPQRLP------SPTSAPQQPASQAAPPTQGQGRQSR--------------P 535

Query: 79  GRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGG--APRRRAHLTGGPPRRRPPR 136
             G  G P AA   A    P  +R A PP +     V G   P+      GG  R+ PP+
Sbjct: 536 VAGGPGAPPAARPPA---SPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQ 592

Query: 137 LAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQP 196
                  P    P  +   A    R    + + PR   P PA           RP     
Sbjct: 593 KP-----PGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAG----------RP----- 632

Query: 197 PPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPSAHSP 244
                P LAQ P  +       +P P+ A    PP P    +P+   P
Sbjct: 633 ----KPQLAQKPSQD-------VPPPATAAAGGPPHPQLKASPAQAQP 669



 Score = 37.7 bits (86), Expect = 0.017
 Identities = 46/166 (27%), Positives = 56/166 (33%), Gaps = 18/166 (10%)

Query: 201 SPGLAQSPG-VELHARTLSLPAPSPAPCLPPPA---PPAARTPSAHSPAHTHFTLTLAEA 256
           S G   SPG + L  +T   PA  PA   PPP    P     P    P          + 
Sbjct: 432 SHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQ 491

Query: 257 HTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAPVPSTARARSPGARRGARE 316
           H   L P  G       P     P+     ASQ +PP       S   A  PGA   AR 
Sbjct: 492 HLSGLGPPAGSPLPQRLPSPTSAPQQP---ASQAAPPTQGQGRQSRPVAGGPGAPPAAR- 547

Query: 317 LAPRAGRRRQPSGRTSWRRRARREQRDREPAVCGAWPRGSHAAGAG 362
                     P    S +R+A   Q  R+ +V G  P  +  A  G
Sbjct: 548 ----------PPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPG 583



 Score = 32.0 bits (71), Expect = 0.91
 Identities = 26/84 (30%), Positives = 31/84 (36%), Gaps = 4/84 (4%)

Query: 230 PPAPPAARTPSAHSPAHTHFTLTLAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQ 289
           PP PP    P AHSP  T    T     +  + PA       PG   GG   +  S A +
Sbjct: 30  PPPPP----PGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGGFFSSLSNAVK 85

Query: 290 TSPPAPPAPVPSTARARSPGARRG 313
            +  A  A         S GA RG
Sbjct: 86  QTTAAAAATFSEQVGGGSGGAGRG 109


>gi|33286436 gametogenetin [Homo sapiens]
          Length = 652

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 92/342 (26%), Positives = 111/342 (32%), Gaps = 89/342 (26%)

Query: 79  GRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGG---------P 129
           G G GGL   AA GA +     ++   PPG+  PL  G   R      GG         P
Sbjct: 270 GGGGGGL--FAASGAISYAEVLKQGPLPPGAARPL--GEVSRGAQEAEGGDGDGEGCSGP 325

Query: 130 PRRRPPRLAAAHGLPASEAPGLRP--------DSARTRLRL------------RLASARL 169
           P     +  A    P +  PG +P        D      R             R A+   
Sbjct: 326 PSAPASQARALPPPPYTTFPGSKPKFDWVSAPDGPERHFRFNGAGGGIGAPRRRAAALSG 385

Query: 170 PRGLPPAPAAGLWRA-GCTRLRPLLLQPPPMLSP----GLAQSPGVELHARTLSLPAPSP 224
           P G PP P   +  A G  R  P LL PP  + P    G    PG          P    
Sbjct: 386 PWGSPPPPPEQIHSAPGPRRPAPALLAPPTFIFPAPTNGEPMRPGP---------PGLQE 436

Query: 225 APCLPPPAPPAARTPSAHSPAHTHFTLTLAEAHTRALTPARGGGEGDPGPIVGGRPENED 284
            P LPPP PP    P A  P      L +A                   P+  G    E 
Sbjct: 437 LPPLPPPTPPPTLQPPALQPT----PLPVAP------------------PLTPGLGHKES 474

Query: 285 SLASQTSPPAPP------APVPSTARA-----RSPGARRGARELAPRAGRRRQPSGRTSW 333
           +LA   +P  PP      AP PS A A      SP     A   AP   R R+  G  + 
Sbjct: 475 ALAPTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPIKTRTRRNKGSRAA 534

Query: 334 RRRARRE------QRDREPAVCGAWPRGSHAAGAGWTAVAAG 369
           R   R++       R+R  A     P  S   G G  A   G
Sbjct: 535 RGATRKDGLHGDGPRERATATV---PDSSGGGGGGSGASQTG 573



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 64/217 (29%), Positives = 81/217 (37%), Gaps = 56/217 (25%)

Query: 153 PDSARTRL---RLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQPPPMLSPGLAQSPG 209
           PDS RT L    +   + RL RGL      G+W  G      L++   P  SP       
Sbjct: 24  PDSRRTSLVEPEMTSQAMRLTRGL------GVWFPGSATPPGLMVPREPQASPS------ 71

Query: 210 VELHARTLSLPAPSPAPCLPPPAPPAARTPSAHSPAHT--------HFTLTLAEAHTRAL 261
                 TL L    P+P +PPP   AA +    +PA T                   R L
Sbjct: 72  ------TLPLTLERPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVPRIRRL 125

Query: 262 TPARGGGEGDP---GPIVGGRPENEDSL-------ASQTSPP----APPAPVPSTARARS 307
             A   G+GDP    P+    P  + S+        SQ  PP     PP P+PS    R 
Sbjct: 126 LEASHRGQGDPPSLRPLKPPPPPRQLSVKDTVPRAPSQFPPPLETWKPPPPLPS---ERQ 182

Query: 308 PGARRGARELA--------PRAGRRRQPSGRTSWRRR 336
           P  RR    LA         +AG R Q  G+T+ R R
Sbjct: 183 PADRRITPALATPASPPTESQAGPRNQ--GQTAGRAR 217



 Score = 30.4 bits (67), Expect = 2.7
 Identities = 31/113 (27%), Positives = 43/113 (38%), Gaps = 7/113 (6%)

Query: 239 PSAHSPAHTHFTLTLAEAHTRALTPARG------GGEGDPGPIVGGRPENEDSLASQT-S 291
           PS  +P     +L   E  ++A+   RG      G    PG +V   P+   S    T  
Sbjct: 19  PSDRAPDSRRTSLVEPEMTSQAMRLTRGLGVWFPGSATPPGLMVPREPQASPSTLPLTLE 78

Query: 292 PPAPPAPVPSTARARSPGARRGARELAPRAGRRRQPSGRTSWRRRARREQRDR 344
            P+P  P P  A A S      A  L P   + ++P+G    R R   E   R
Sbjct: 79  RPSPVMPPPEEAAAVSAPPPAPAGTLLPGPSKWQKPAGTPVPRIRRLLEASHR 131


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 72/270 (26%), Positives = 92/270 (34%), Gaps = 45/270 (16%)

Query: 78  PGRGRGG----LPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRR 133
           P  G  G    +P AAA+ AG +          P    P +  G     A    GP    
Sbjct: 129 PPEGSAGSCAPVPAAAAVAAGPE----------PAPAGPAKPAGPAALAARAGPGPGPGP 178

Query: 134 PPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPL- 192
            P      G PA       P +A+T   L  ++A L      APA  L   G   L PL 
Sbjct: 179 GPGPGPGPGKPAG------PGAAQT---LNGSAALLNSHHAAAPAVSLVNNGPAALLPLP 229

Query: 193 -------LLQPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPSAHSPA 245
                  ++Q PP +      +P         +  AP+ AP  PPPAP     P    P 
Sbjct: 230 KPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARP----PG 285

Query: 246 HTHFTLTLAEAHTRALTPARGGGEG---DPGPIVGGRPENEDSLASQTSPPAPPAPVPST 302
           H     T A A         GG  G    P P  GG       ++ Q  P A  A     
Sbjct: 286 HPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGG----PAGVSGQPGPGAAAAAPAPG 341

Query: 303 ARARSPGARRGARELAPRAGRRRQPSGRTS 332
            +A SP   +   + AP A +    SG  S
Sbjct: 342 VKAESP---KRVVQAAPPAAQTLAASGPAS 368



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 72/266 (27%), Positives = 85/266 (31%), Gaps = 61/266 (22%)

Query: 78  PGRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRL 137
           P    G  P A A GA    P      +PP           P  RA   GG P+R  P  
Sbjct: 67  PAGAAGAGPAAPAEGAPGAAP------EPP-----------PAGRARPGGGGPQRPGPPS 109

Query: 138 AAAHGLPASEAPGLR-----PDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPL 192
                +PA  AP        P+ +        A+A +  G  PAPA     AG   L   
Sbjct: 110 PRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAAL--- 166

Query: 193 LLQPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPAART-------PSAHSPA 245
                    PG    PG          P P P P   P  P AA+T        ++H  A
Sbjct: 167 ----AARAGPGPGPGPG----------PGPGPGPG-KPAGPGAAQTLNGSAALLNSHHAA 211

Query: 246 HTHFTLT------------LAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSPP 293
               +L              A   T   TP   G    P P     P      A   +PP
Sbjct: 212 APAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPP 271

Query: 294 APPAPVPSTARARSPGARRGARELAP 319
            PP P P+T  AR PG   G    AP
Sbjct: 272 -PPPPAPATL-ARPPGHPAGPPTAAP 295



 Score = 42.0 bits (97), Expect = 9e-04
 Identities = 75/273 (27%), Positives = 93/273 (34%), Gaps = 61/273 (22%)

Query: 78  PGRGRGGLPGAA-ALGAGAQQPRRRRLAQP--------PGSRAPLQVGGAPRRRAHLTGG 128
           PG G+   PGAA  L   A        A P        P +  PL    AP        G
Sbjct: 184 PGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAP--------G 235

Query: 129 PPRRRPPRL-AAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWR---- 183
              + PP + AAA   PA+ +P   P  A        A A  P   PPAPA  L R    
Sbjct: 236 TVIQTPPFVGAAAPPAPAAPSPPAAPAPA--------APAAAPPPPPPAPAT-LARPPGH 286

Query: 184 -AGCTRLRPLLLQPPPML-----SPGLAQSPGVELH--ARTLSLPAPSPAPCLPPP---- 231
            AG     P +  PPP       S G A +P       A     P P  A   P P    
Sbjct: 287 PAGPPTAAPAV--PPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKA 344

Query: 232 ---------APPAARTPSAHSPAHTHFTLTLAEAHTRAL-------TPARGGGEGDPGPI 275
                    APPAA+T +A  PA T  ++ +      AL        PA G   G P   
Sbjct: 345 ESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGA 404

Query: 276 VGGRPENEDSLASQTSPPAPPAPVPSTARARSP 308
            G   ++     + T+        P+    R P
Sbjct: 405 AGAVTQSLSRTPTATTSGIRATLTPTVLAPRLP 437


>gi|60460889 Myb protein P42POP [Homo sapiens]
          Length = 399

 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 72/255 (28%), Positives = 93/255 (36%), Gaps = 53/255 (20%)

Query: 86  PGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRR-AHLTGGPPRRRPPRLAAAHGLP 144
           P       G  +P+ R  + PP +  P+Q+   PR   +     PP   PP LA     P
Sbjct: 185 PSCTPQEGGCPRPKERE-SPPPSALQPVQL---PRLALSPPPPAPPLPPPPPLAQVAPSP 240

Query: 145 ASEAPGLRP-------DSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQPP 197
            S  P  RP       D +   LR +  +A   R L     AG  R G  +L   L    
Sbjct: 241 PSPPPPPRPPPTLSASDPSLDFLRAQQETANAIREL-----AGTLRQGLAKLSEALSALL 295

Query: 198 PMLSPGLAQSPGVELHARTLSLPAPSPAP-----CLPPPAPPAARTPSAHSPAHTHFTLT 252
           P+L       PG  + +    LP P P P      LPPPAP    TP   S         
Sbjct: 296 PLL-------PGTPVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEITPEPVS--------V 340

Query: 253 LAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAPVPSTARARSPGARR 312
           +A     A+  AR       G I+  R E       + +P  PPAP+P       P  RR
Sbjct: 341 VAAVVDGAVVAAR-------GVIIAPRSE-------EGAPRPPPAPLP--PHDSPPHKRR 384

Query: 313 GARELAPRAGRRRQP 327
                  R GR + P
Sbjct: 385 KGFPTRKRRGRWKSP 399



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 65/240 (27%), Positives = 76/240 (31%), Gaps = 66/240 (27%)

Query: 86  PGAAA--LGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGL 143
           PG AA   GAGA++P     +QPP   A       P+R          RR    A +   
Sbjct: 122 PGVAAPGAGAGAEEPPAAPSSQPPPPSA------CPQRYVLSEDRREDRRADTSAHSKAG 175

Query: 144 PASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQPPPMLSPG 203
            +S  P  RP                       P  G    GC R +     PP  L P 
Sbjct: 176 SSSPEPWARPSCT--------------------PQEG----GCPRPKERESPPPSALQP- 210

Query: 204 LAQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPSAHSPAHTHFTLTLAEAHTRALTP 263
             Q P        L+L  P PAP LPPP P A   PS  SP           A   +L  
Sbjct: 211 -VQLP-------RLALSPPPPAPPLPPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLDF 262

Query: 264 ARGGGEGDPG-----------------------PIVGGRPENEDSLASQTSPPAPPAPVP 300
            R   E                           P++ G P   DSL     PP PP P P
Sbjct: 263 LRAQQETANAIRELAGTLRQGLAKLSEALSALLPLLPGTP--VDSLPPPLPPPPPPPPPP 320


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 62/250 (24%), Positives = 77/250 (30%), Gaps = 20/250 (8%)

Query: 84   GLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGL 143
            G P A  L  GA       L  P G  A   + GAP         PP   PP        
Sbjct: 1045 GSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPT--------PPAATPPSPKGGPAT 1096

Query: 144  PASEA----PGLRPDSARTRLRL--RLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQPP 197
            P+ +     P   P S +  L       +   P   PP+P  GL               P
Sbjct: 1097 PSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1156

Query: 198  PMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPSAHSPAHTHFTLTL---- 253
            P    GLA  P         + P PSP   L  P+P  A T  A +P      L      
Sbjct: 1157 PSPKGGLATPPPKGAPTTPAATP-PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1215

Query: 254  -AEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAPVPSTARARSPGARR 312
             A     A  P+  GG   P P            + +  P  PP     T  A +P + +
Sbjct: 1216 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLK 1275

Query: 313  GARELAPRAG 322
            G     P  G
Sbjct: 1276 GGLATPPHKG 1285



 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 71/269 (26%), Positives = 85/269 (31%), Gaps = 46/269 (17%)

Query: 76   ACPGRGRGGLP-----GAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPP 130
            A P   +GGL      GA    A      +  LA PP   AP      P         PP
Sbjct: 1108 ATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPP 1167

Query: 131  RRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLR 190
             +  P   AA   P S   GL   S +        +   P   PP+P  GL         
Sbjct: 1168 PKGAPTTPAA--TPPSPKGGLATPSPK-------GAPTTPAATPPSPKGGLATPSPKGAP 1218

Query: 191  PLLLQPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPSAHSPAHTHFT 250
                  PP    GLA              P+P  AP  P   PP+ +   A  P      
Sbjct: 1219 TTPAATPPSPKGGLAT-------------PSPKGAPTTPAATPPSPKGGPATPPPKG--- 1262

Query: 251  LTLAEAHTRALTPARGGG------EGDPGPIVGGRPENEDSLASQTSP----PAPPAPVP 300
               A     A  P+  GG      +G P P V   P  +   A  TSP    P PPA  P
Sbjct: 1263 ---APTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPA--TSPPKGAPTPPAATP 1317

Query: 301  STARARSPGARRGARELAPRAGRRRQPSG 329
             + +  SPG         P A     P G
Sbjct: 1318 PSPKG-SPGTPPPKGAPTPPAVTPPSPKG 1345



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 68/312 (21%), Positives = 95/312 (30%), Gaps = 48/312 (15%)

Query: 27   IPPR---LPIRMTWGIPRESGIQKAHTRSPAQYSQTRLRRRRQGAVIVGRRRACPGRGRG 83
            +PP+    P  +    P+E     A  ++PA    +   ++ +         A P     
Sbjct: 880  LPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGA 939

Query: 84   GLPGAAALGA---GAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAA 140
              P AA   +   G   P  +    PP +  P   GG           PP   PP     
Sbjct: 940  PTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGG 999

Query: 141  HGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQPPPML 200
               P+ +     P       +   A+   P+G    PAA                P P  
Sbjct: 1000 PATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAA--------------TPPSPKG 1045

Query: 201  SPGLAQSPGVELHARTLSLPAPSPAPCLP----PPAPPAARTPSAHSPAHTHFTLTLAEA 256
            SP     P         +LP+P   P  P     P PPAA  PS                
Sbjct: 1046 SPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKG------------- 1092

Query: 257  HTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAPVPSTARARSPGARRGARE 316
                  PA    +G P P     P  +  LA   +PP   AP   T  A +P + +G   
Sbjct: 1093 -----GPATPSPKGAPMPPAATPPSPKGGLA---TPPHKGAP---TTPAATPPSPKGGLA 1141

Query: 317  LAPRAGRRRQPS 328
              P  G    P+
Sbjct: 1142 TPPPKGAPTTPA 1153



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 70/277 (25%), Positives = 84/277 (30%), Gaps = 63/277 (22%)

Query: 76   ACPGRGRGGLP-----GAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPP 130
            A P   +GGL      GA    A      +  LA P    AP      P         P 
Sbjct: 1154 ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS 1213

Query: 131  RRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLP--PAPAAGLWRAGCTR 188
             +  P   AA   P S   GL   S +       A+   P+G P  P P         T 
Sbjct: 1214 PKGAPTTPAA--TPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAAT- 1270

Query: 189  LRPLLLQPPPMLSPGLAQSPGVELHARTLSLP--------------APSPAPCLPP---- 230
                    PP L  GLA  P        +  P              AP+P    PP    
Sbjct: 1271 --------PPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKG 1322

Query: 231  ----PAPPAARTPSAHSPAHTHFTLTLAEAHTRALTPARGGGEGDPGPIVGGRPENEDSL 286
                P P  A TP A +P     T TL      A TP+  GG   P              
Sbjct: 1323 SPGTPPPKGAPTPPAVTPPSPKGTPTLP-----ATTPSSKGGPTTP-------------- 1363

Query: 287  ASQTSPPAPPAPVPSTARARS---PGARRGARELAPR 320
             S    P PPA  PS     +   P  +RG    +P+
Sbjct: 1364 -SSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPK 1399



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 48/167 (28%), Positives = 58/167 (34%), Gaps = 34/167 (20%)

Query: 193  LLQPPPMLSPGLAQSPGVELHARTLSLP-APSPAPCLPP-----PAPPAARTPSAHSPAH 246
            +L  P   S   A SP V       SLP APSP P LPP     P+ P     S   P  
Sbjct: 1781 VLPKPESASVSAAPSPPV-------SLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKP-- 1831

Query: 247  THFTLTLAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSP-------PAPPAPV 299
                  LA A    L P        P PI GG P  +  L +  +P       P P A  
Sbjct: 1832 ------LAPADEDELLPLI-----PPEPISGGVP-FQSVLVNMPTPKSAGIPVPTPSAKQ 1879

Query: 300  PSTARARSPGARRGARELAPRAGRRRQPSGRTSWRRRARREQRDREP 346
            P T   +  G    + E  P    +      T   + A   + D EP
Sbjct: 1880 PVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEP 1926



 Score = 38.5 bits (88), Expect = 0.010
 Identities = 45/196 (22%), Positives = 63/196 (32%), Gaps = 23/196 (11%)

Query: 106  PPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLA 165
            P     P      P  +     G P   PP       +P+ +     P            
Sbjct: 1363 PSSKEGPTPPAATPSHK-----GGPAMTPPSPKRGPAIPSPKGDPTSP------------ 1405

Query: 166  SARLPRGLPPAPAAGLWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARTLSLPAPSPA 225
             A +P     APA  + R G        L PP +    L ++P         + P+    
Sbjct: 1406 -AVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGD 1464

Query: 226  PCLPPPAPPAARTPSAHSPAHTHFTLTLAEAHTRALTPARGGGEGDPGPIVGGRPENEDS 285
            P LP   PP+ + P A     T  +   A A     TPA  G    P  I     E   +
Sbjct: 1465 PTLPAVTPPSPKEPPAPKQVATSSSPKKAPA-----TPAPMGAPTLPAVIPSSPKEVPAT 1519

Query: 286  LASQTSPPAPPAPVPS 301
             +S+  P AP A + S
Sbjct: 1520 PSSRRDPIAPTATLLS 1535



 Score = 38.1 bits (87), Expect = 0.013
 Identities = 50/202 (24%), Positives = 68/202 (33%), Gaps = 26/202 (12%)

Query: 174  PPAPAAGLWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAP 233
            PP+P      +  T L P  +  PP  +P    +P V      ++LP P   P  P P  
Sbjct: 858  PPSPKGAPTPSAVTPLSPKGVTLPPKETP----TPSV------VNLPFPKEGPATPAPKQ 907

Query: 234  PAARTPSAHSPAHTHFTLTL-----------AEAHTRALTPARGGGEGDPGPIVGGRPEN 282
              A + ++ SP     T              A     A  P+  GG   P P     P  
Sbjct: 908  APALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPA 967

Query: 283  EDSLASQTSPPAPP---APVPSTARARSP--GARRGARELAPRAGRRRQPSGRTSWRRRA 337
                + +  P  P    AP P  A   SP  G    + + AP       PS + S     
Sbjct: 968  ATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATP 1027

Query: 338  RREQRDREPAVCGAWPRGSHAA 359
              +     PA     P+GS AA
Sbjct: 1028 FPKGASTPPAATPPSPKGSPAA 1049



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 27/99 (27%), Positives = 37/99 (37%), Gaps = 2/99 (2%)

Query: 224 PAPCLPPPAPPA-ARTPSAHSPAHTHFTLTLAEAHTRALTPARGGGEGDPGPIVGGRPEN 282
           P P LPPP  PA  + P + +   + F      A T    P      G   P+ G  PE 
Sbjct: 41  PGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPL-GTAPEA 99

Query: 283 EDSLASQTSPPAPPAPVPSTARARSPGARRGARELAPRA 321
              L +   PP  PA +   +   +P  +      AP A
Sbjct: 100 PTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLA 138



 Score = 30.4 bits (67), Expect = 2.7
 Identities = 30/113 (26%), Positives = 46/113 (40%), Gaps = 14/113 (12%)

Query: 220 PAPSPAPCLPPPAPPAARTPSAHSP-AHTHFTLTLAEAHTRALT--PARGGGEGDPGP-- 274
           PA + +P   PP+P  A TPSA +P +    TL   E  T ++   P    G   P P  
Sbjct: 850 PATTHSPT--PPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQ 907

Query: 275 -----IVGGRPENEDSLASQTSPPAPPAP--VPSTARARSPGARRGARELAPR 320
                +    P+   +  +    PA P+P   P+   A  P  + G    +P+
Sbjct: 908 APALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPK 960



 Score = 28.9 bits (63), Expect = 7.7
 Identities = 28/115 (24%), Positives = 44/115 (38%), Gaps = 6/115 (5%)

Query: 199 MLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPSAHSPAHTHFTLTLAEAHT 258
           +++P   + P  ++ A TL +P   P P  P        +     P         A    
Sbjct: 484 VMAPVAPKEPSTQV-ATTLRIPVSPPLPD-PEDLKNLPSSVLVKFPTQKDLQTVPASLEG 541

Query: 259 RALTPARGG--GEGDPG--PIVGGRPENEDSLASQTSPPAPPAPVPSTARARSPG 309
              +PA+ G   + DP   P+V   P+N  S  S +S P  P    +T   +S G
Sbjct: 542 APFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLG 596



 Score = 28.9 bits (63), Expect = 7.7
 Identities = 54/260 (20%), Positives = 81/260 (31%), Gaps = 40/260 (15%)

Query: 86   PGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLPA 145
            P A    A +  P++   A P    AP      P     +   P  RR P    A  L  
Sbjct: 1478 PPAPKQVATSSSPKKAP-ATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSK 1536

Query: 146  SEAPGLRPDSARTRLRLRLASARLPRGLPP---APAAGLWRAGCTRLRPLLLQPPPMLSP 202
                 L P  A     + + S +    +P    APA    +   +         PP ++P
Sbjct: 1537 KTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASS---------PPAVTP 1587

Query: 203  GL---AQSPGVELHARTLSLPAPSPAPCLP----------------------PPAPPAAR 237
                 A SP   L    ++ P+P  AP  P                      PP  P++ 
Sbjct: 1588 STYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSL 1647

Query: 238  TPSAHSPAHTHFTLTLAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQT--SPPAP 295
              S  SPA     +           PA+ G       +V   PE+   + + T   P   
Sbjct: 1648 KDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTK 1707

Query: 296  PAPVPSTARARSPGARRGAR 315
             +   S      P A+ G++
Sbjct: 1708 KSSATSPPICPDPSAKNGSK 1727


>gi|77681565 NG5 protein [Homo sapiens]
          Length = 306

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 57/184 (30%), Positives = 65/184 (35%), Gaps = 31/184 (16%)

Query: 135 PRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLL 194
           PRL A  GL +S A   R  S+   L       R P   PP PAAG    GC  L  +  
Sbjct: 57  PRLGAG-GLASSAATAQRGPSSSATL------PRPPHHAPPGPAAGAPPPGCATLPRM-- 107

Query: 195 QPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPA--ARTPSAHSPAHTHFTLT 252
            P P L     + P          LP P PA   PPP  PA  A+ P    P H     T
Sbjct: 108 PPDPYLQETRFEGP----------LPPPPPAAAAPPPPAPAQTAQAPGFVVPTHAGTVGT 157

Query: 253 L------AEAHTRALTPARGGGEGDP--GPIVGGRPENEDSLASQTSPPAPPAPVPSTAR 304
           L      A  +   L P        P   P  GG P       + T PP P  P  +   
Sbjct: 158 LPLGGYVAPGYPLQLQPCTAYVPVYPVGTPYAGGTPGGTG--VTSTLPPPPQGPGLALLE 215

Query: 305 ARSP 308
            R P
Sbjct: 216 PRRP 219



 Score = 37.7 bits (86), Expect = 0.017
 Identities = 26/91 (28%), Positives = 34/91 (37%), Gaps = 6/91 (6%)

Query: 220 PAPSPAPCLPPPAPPAARTPSAHSPAHTHFTLTLAEAHTRALTPARGGGEGDPGPIVGGR 279
           P  +P P   PPAPP    PS+H   H H+     ++ T  L     GG           
Sbjct: 19  PYNAPQPPAEPPAPPPQAAPSSHHHHHHHY----HQSGTATLPRLGAGGLASSAATAQRG 74

Query: 280 PENEDSL--ASQTSPPAPPAPVPSTARARSP 308
           P +  +L      +PP P A  P    A  P
Sbjct: 75  PSSSATLPRPPHHAPPGPAAGAPPPGCATLP 105


>gi|169160903 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 426

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 72/254 (28%), Positives = 87/254 (34%), Gaps = 20/254 (7%)

Query: 75  RACPGRGRGGLPGAAALGAGAQQ-PRRRRLAQPP---GSRAPLQVGGAPRRRAHL--TGG 128
           RA    G     GA  +GA     P  RRL + P      +P    GAPR R       G
Sbjct: 56  RAREWEGAAWAAGATGVGAALLALPGSRRLGRVPLTFREASPGPAPGAPRARGSCGREPG 115

Query: 129 PPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTR 188
           P RRR P  A      A+ A   R  S    L   + S   P   P  P     R     
Sbjct: 116 PRRRRAPSSAGKRPAAAARAAPPRQRSLARCLPRSVGSCVRPSVGPSLPRRHCRRHCRCH 175

Query: 189 LRPLLLQPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPSAHSPAHTH 248
            R   L  PP L P L  +    L A      APS +     P P   R  +  SPA   
Sbjct: 176 CRRRPLPKPPPLQPRLGSASPPRLAAPLAGSRAPSLS-----PFPRRCRRRAERSPAGHG 230

Query: 249 FTLTLAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAPVPSTARARSP 308
             L  + +    +  AR    G+   + G R        +  SPP P  P    A     
Sbjct: 231 LPLPRSLSRGGEVVGARRRRGGEERRVRGRRQG-----CALGSPPIPAGP----AAPGRA 281

Query: 309 GARRGARELAPRAG 322
           G RR AR+   R G
Sbjct: 282 GERRAARQWRKRGG 295



 Score = 37.0 bits (84), Expect = 0.028
 Identities = 62/245 (25%), Positives = 77/245 (31%), Gaps = 49/245 (20%)

Query: 19  LGPSAYSKIPPRLPIRMTWG-----IPRESGIQKAHTRSPAQYSQTRLRRRRQGAVIVGR 73
           L P   S  PPRL   +         P     ++   RSPA +     R   +G  +VG 
Sbjct: 187 LQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGA 246

Query: 74  RRACPG---RGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRA----HLT 126
           RR   G   R RG   G A             L  PP    P   G A  RRA       
Sbjct: 247 RRRRGGEERRVRGRRQGCA-------------LGSPPIPAGPAAPGRAGERRAARQWRKR 293

Query: 127 GGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGC 186
           GG P   P   A   G+     P  R  S   R               P+PA   W+ G 
Sbjct: 294 GGGPGVSPREGAQGEGVRGGVTPRARGSSTCLR---------------PSPAT--WQGGA 336

Query: 187 TRLRPLLLQPPPMLSPG--LAQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPSAHSP 244
              R +    P + +P     + PG      T S P   P       AP   R   +   
Sbjct: 337 P-YRAIFAAGPRLSAPSAEAEEVPG----GHTASNPTYEPLSSRRTKAPSEGRDSPSSPA 391

Query: 245 AHTHF 249
             TH+
Sbjct: 392 TSTHY 396



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 45/145 (31%), Positives = 52/145 (35%), Gaps = 24/145 (16%)

Query: 221 APSPAPC-----LPPPAPPAARTPSAHS----PAHTHFTLTLAEAHTRALTPARGGG--- 268
           AP PA C      PPP  PA + P   +     A      T   A   AL  +R  G   
Sbjct: 30  APGPAVCSPTARAPPPILPAPQRPPTRAREWEGAAWAAGATGVGAALLALPGSRRLGRVP 89

Query: 269 ----EGDPGPIVGGRPENEDSLASQTSPPAPPAP------VPSTARARSPGARRGARELA 318
               E  PGP   G P    S   +  P    AP        + ARA  P  R  AR L 
Sbjct: 90  LTFREASPGP-APGAPRARGSCGREPGPRRRRAPSSAGKRPAAAARAAPPRQRSLARCLP 148

Query: 319 PRAGRRRQPS-GRTSWRRRARREQR 342
              G   +PS G +  RR  RR  R
Sbjct: 149 RSVGSCVRPSVGPSLPRRHCRRHCR 173


>gi|239745807 PREDICTED: keratin associated protein 4-9 [Homo
           sapiens]
          Length = 254

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 54/187 (28%), Positives = 69/187 (36%), Gaps = 9/187 (4%)

Query: 129 PPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPA--PAAGLWRAGC 186
           PP   PP  A A   PA+  P      A   L    A+ R P   PPA  PA     A  
Sbjct: 26  PPAAGPPAAAPAVVYPAAAGPSAASLCAANPLVPAPAAVRPPVAGPPATAPAVVCPAAAG 85

Query: 187 TRLRPLLLQPPPMLSPGLAQSPGVELHARTLSLPAPS---PAPCLPPPAPPAARTPSAHS 243
                L    P  ++P   + P   L A + +  AP+   PA   P  A   A +P+A +
Sbjct: 86  PSAASLRAANPLAVAPAAVRRPAATLGAASPAAVAPAAVCPAAASPSAASLCAASPTAAA 145

Query: 244 PAHTHFTLTLAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAPVPSTA 303
           PA      + A A   A+ PA           V   P    ++A   S PA PAP     
Sbjct: 146 PA----AASPAAAAPLAVNPAAAAPAAACVQSVAESPATPLAIAQPVSSPAAPAPCAVPP 201

Query: 304 RARSPGA 310
            A  P A
Sbjct: 202 LAAEPTA 208



 Score = 30.0 bits (66), Expect = 3.5
 Identities = 32/106 (30%), Positives = 42/106 (39%), Gaps = 17/106 (16%)

Query: 220 PAPSPAPCLPPPAPPAARTPSAHSPAHT-HFTLTLAEAHTRALTPARGGGEGDPGPIVGG 278
           PA +PA   PP A P A  P+   PA       +L  A+     PA         P V G
Sbjct: 17  PAAAPAAVRPPAAGPPAAAPAVVYPAAAGPSAASLCAANPLVPAPAA------VRPPVAG 70

Query: 279 RPENEDSLASQTSPPAPPAPVPSTARARSPGARRGARELAPRAGRR 324
            P    ++      PA   P  ++ RA +P A      +AP A RR
Sbjct: 71  PPATAPAVVC----PAAAGPSAASLRAANPLA------VAPAAVRR 106


>gi|238624195 hypothetical protein LOC221545 isoform 3 [Homo
           sapiens]
          Length = 496

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 84/303 (27%), Positives = 103/303 (33%), Gaps = 38/303 (12%)

Query: 28  PPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTRLRRRRQGAVIVGRRRACPGRGRGG-LP 86
           P   P+R   G  R  G  +A    P   +    R  R G    G RR    R R   LP
Sbjct: 40  PSSKPVR---GAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLP 96

Query: 87  GAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLPAS 146
           G  A+  G  Q   R    P   R P+        R  L G     R P  A +   PA 
Sbjct: 97  GLRAVRRGQGQAAGRVCVAPDSPRLPVP-------RGDLKGRGREIRSPAAAPSRSSPAQ 149

Query: 147 EAPGLRPDSARTRLRLRLASARLPRGLPP----APAAGLWRAGCTRLRPLLLQPP----P 198
             P  RP       RL L       G P      P    W+ G    R    + P     
Sbjct: 150 TRPAGRPQQP---ARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTED 206

Query: 199 MLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPSAHSPAHTHFTLTLAEAHT 258
            L PG    P +  H+ T + P+   +P    P PP  R P+   P      L   +A +
Sbjct: 207 QLYPGTLPFPPLWPHSTTTTSPS---SPLFWSPLPP--RLPTQRLPQVPPLPLPQIQALS 261

Query: 259 RA-LTPARGGGEGDPGP-IVGGRPENEDSLASQTSPPAP------PAPVPSTARARSPGA 310
            A +    G GE  PGP +  G  +   SL     PP P      P  VP TA   SP  
Sbjct: 262 SAWVVLPPGKGEEGPGPELHSGCLDGLRSLFE--GPPCPYPGAWIPFQVPGTAHP-SPAT 318

Query: 311 RRG 313
             G
Sbjct: 319 PSG 321


>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
          Length = 1003

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 89/306 (29%), Positives = 108/306 (35%), Gaps = 54/306 (17%)

Query: 81  GRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPR---- 136
           G GG  G    G G   P    L  PP S  P  +       A  T  PP   PP+    
Sbjct: 644 GAGGPSGEPFSGLGDLSP----LLFPPLSAPPTLIALNSALLA-ATLDPPSGTPPQPCVL 698

Query: 137 LAAAHGLPASEAPGLRPDSARTRL-RLRLASARLPRGLPPAPAAGLWR-----AGCTRLR 190
            A   G P S       D   + L +    S R P+ L P   A L              
Sbjct: 699 SAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGAL 758

Query: 191 PLLLQPP-PMLSP--GLAQSPG-------------VELHARTLSLPAPSP-APCLPPPAP 233
           P LLQPP P+LS   GL   PG             +    ++L +P   P APCLPP +P
Sbjct: 759 PSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESP 818

Query: 234 PAARTPSAHSPAHTHFTLTLAEAHTRALTPA----RGGGEGDPGPIVGGRPENEDSLASQ 289
            +A  P    P  +     LA  H     P      G G G  G   GG       L   
Sbjct: 819 ASALEPEPARPPLS----ALAPPHGSPDPPVPELLTGRGSGKRGRRGGG------GLRGI 868

Query: 290 TSPPAPPAPVPSTARARSPGARRGARELAPRAGRRRQPSGRTSWR-RRARREQRDREPAV 348
                P       AR R PG+RR    LA + G R   +G+     RR    Q + E A 
Sbjct: 869 NGEARP-------ARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAE 921

Query: 349 CGAWPR 354
            GA P+
Sbjct: 922 GGAEPK 927



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 72/250 (28%), Positives = 91/250 (36%), Gaps = 50/250 (20%)

Query: 106 PPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLPASEAPG--LRPDSARTRLRLR 163
           PP +R P +V         L GGP    P   + +   P    PG    P  A       
Sbjct: 142 PPSARPPCRVPPT----TPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGG 197

Query: 164 LASAR-LPRGL------PPAPAAGL------WRAGC-TRLRPLLLQPPPMLSPGLAQSPG 209
            +S R LPRG       PP PA  L      W A   + L P  L  PP  +P  + SP 
Sbjct: 198 SSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPP--APHASSSP- 254

Query: 210 VELHARTLSLPAPSPAPCL-------PPPAPPAARTPSAHSPAHTHFTLTLAEAHTRALT 262
                       PS  P         PPP PP+   P+   PA +   ++ A  H   + 
Sbjct: 255 ------------PSDPPLFHCSDALTPPPLPPSNNLPAHPGPA-SQPPVSSATMHLPLVL 301

Query: 263 PARGGGEGDPGPIVGGRPENEDSLASQTSPPA-PPAPVPSTARARSPGAR----RGAREL 317
              GG     GP  G  P    SL S  +    PP P PST + R P A+      +  L
Sbjct: 302 GPLGGAPTVEGP--GAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSL 359

Query: 318 APRAGRRRQP 327
            P   R R+P
Sbjct: 360 RPSQRRPRRP 369



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 65/239 (27%), Positives = 83/239 (34%), Gaps = 35/239 (14%)

Query: 104 AQPPGSRAPL---QVGGAPRRRAHLTGGPPRRRPPRLAAAHGLP-ASEAPGLRPDSARTR 159
           A P  S+AP+    V  +P     +  GP    PP LA     P  S   GL    A   
Sbjct: 477 APPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPP-LAGGEAFPFPSPEQGLALSGAGFP 535

Query: 160 LRLRLASARLPRGLPPAPAA------GLWRAGCTRLRPLLLQPPP-----MLSPGLAQSP 208
             L      L  G PP          G+   G  +  P  L PPP      L+PG  + P
Sbjct: 536 GMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGP 595

Query: 209 GVELHARTLSLPAPSPAPCLPPPAPPAARTPSAHSPAHTHFTLTLAEAHTRALTPARGGG 268
            + +     SL  P P+  LPPP+ P +   ++  P               AL P  G G
Sbjct: 596 SLLV----ASLLPPPPSDLLPPPSAPPSNLLASFLP-------------LLALGPTAGDG 638

Query: 269 EGDPGPIVGGRPENEDSLASQTSPPAPPAPVPSTARARSPGARRGARELAPRAGRRRQP 327
           EG      G   E    L   +    PP   P T  A +      A  L P +G   QP
Sbjct: 639 EGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALL--AATLDPPSGTPPQP 695



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 51/202 (25%), Positives = 68/202 (33%), Gaps = 51/202 (25%)

Query: 109 SRAPLQVGGAPRRRAHLTGGPPRR----------RPPRLAAAHGLPASEAPGLRPDSART 158
           S  P  +G  P    H +  PP             PP L  ++ LPA   P  +P  +  
Sbjct: 236 SLVPSDLGSPPA--PHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSA 293

Query: 159 RLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARTLS 218
            + L L    L  G P     G                PP L+  L            LS
Sbjct: 294 TMHLPLVLGPLG-GAPTVEGPGA---------------PPFLASSL------------LS 325

Query: 219 LPAPSPAPCLPPPAPPAARTPSAHSPAHTHFTLTLAEAHTRALTPARGGGEGDPGPIVGG 278
             A +  P LPPP+    R P A +P+ +H + +L  +  R   P          P V  
Sbjct: 326 AAAKAQHPPLPPPSTLQGRRPRAQAPSASH-SSSLRPSQRRPRRP----------PTVFR 374

Query: 279 RPENEDSLASQTSPPAPPAPVP 300
             E       + S P  PAPVP
Sbjct: 375 LLEGRGPQTPRRSRPRAPAPVP 396



 Score = 35.8 bits (81), Expect = 0.063
 Identities = 46/160 (28%), Positives = 56/160 (35%), Gaps = 19/160 (11%)

Query: 91  LGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGG-----PPRRRPPRLAAAHGLPA 145
           L  G  QP    L  PPG   P    G P   + L        P    PP  A    L A
Sbjct: 564 LTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLA 623

Query: 146 SEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQPPPMLSPGLA 205
           S  P L               A  P G P         +G   L PLL   PP+ +P   
Sbjct: 624 SFLPLLALGPTAGDGEGSAEGAGGPSGEP--------FSGLGDLSPLLF--PPLSAPPTL 673

Query: 206 QSPGVELHARTLSLPAPS-PAPCL---PPPAPPAARTPSA 241
            +    L A TL  P+ + P PC+   P P PP +   +A
Sbjct: 674 IALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTA 713


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 52/222 (23%), Positives = 82/222 (36%), Gaps = 43/222 (19%)

Query: 95  AQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPD 154
           ++QP  + LAQPPG      VG  P ++      P   +PP        P ++ PGL+  
Sbjct: 383 SEQPGPKALAQPPG------VGKTPAQQ------PGPAKPPTQQVGTPKPLAQQPGLQ-S 429

Query: 155 SARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHA 214
            A+     +    +   G  PA  AG  +    +  P     PP   PG A+ P  +   
Sbjct: 430 PAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPT---KPPSQLPGPAKPPPQQ--- 483

Query: 215 RTLSLPAPSPAPCLPPPAPPAARTPSAHSPAHTHFTLTLAEAHTRALTPARGGGEGDPGP 274
                    P P  PPP  P +  P +  P  T               P +  G   P P
Sbjct: 484 ---------PGPAKPPPQQPGSAKPPSQQPGSTK-------------PPPQQPGPAKPSP 521

Query: 275 IVGG--RPENEDSLASQTSPPAPPAPVPSTARARSPGARRGA 314
              G  +P ++   +++ S   P    PS  ++  P ++ G+
Sbjct: 522 QQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGS 563



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 68/302 (22%), Positives = 102/302 (33%), Gaps = 81/302 (26%)

Query: 39  IPRESGIQKAHTRSPAQYSQTRLRRRRQGAVIVGRRRACPGRG---RGGLPGAAALGAGA 95
           + +E G  +   + P Q    +   ++QG          PGR    + G P + +    +
Sbjct: 196 VQKEQGKPEGIIKPPLQQQPPKPIPKQQG----------PGRDPLQQDGTPKSIS----S 241

Query: 96  QQPRRRRLAQPPGSRAPLQ------------------VGGAPRRRAHLTGG-------PP 130
           QQP + + +QPPG+  P+Q                        ++A +  G       P 
Sbjct: 242 QQPEKIK-SQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPS 300

Query: 131 RRRPPRLAAAHGLPASEAPG---LRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCT 187
             +PP      G P ++ PG    +P  A+                PPA  +GL      
Sbjct: 301 PSKPPIQQPTPGKPPAQQPGHEKSQPGPAK----------------PPAQPSGL------ 338

Query: 188 RLRPLLLQPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPSAHSPAHT 247
             +PL  QP  +  P   Q PG      T   PA    P  PP     +  PS+  P   
Sbjct: 339 -TKPLAQQPGTVKPP--VQPPG------TTKPPAQPLGPAKPPAQQTGSEKPSSEQPG-- 387

Query: 248 HFTLTLAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAPVPSTARARS 307
                LA+      TPA+  G   P     G P+         SP   P P  +  +   
Sbjct: 388 --PKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPG 445

Query: 308 PG 309
           PG
Sbjct: 446 PG 447



 Score = 33.5 bits (75), Expect = 0.31
 Identities = 47/214 (21%), Positives = 76/214 (35%), Gaps = 45/214 (21%)

Query: 130  PRRRPPRLAAAHGLPASEAPGLR----------PDSARTRLRLRLASARLPRGLPPAPAA 179
            PR        +H  P+SE+ G +          P  A+T++  +  +  +P+G P  P  
Sbjct: 822  PRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGP 881

Query: 180  GLWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTP 239
                      RP   Q  P  +P  +  P  +    +L+L + + AP   P  P    T 
Sbjct: 882  ----------RPTAGQTVP--TPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTG 929

Query: 240  SAHSPAHTHFTLTLAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQT--------- 290
                   + F+    +A     T  + G     GP   G P  +    SQ          
Sbjct: 930  KLFGFGASIFS----QASNLISTAGQPGPHSQSGP---GAPMKQAPAPSQPPTSQGPPKS 982

Query: 291  ---SPPAPPAPVPSTARARSPGARRGARELAPRA 321
               +PPAP   +P     ++P A +    L P+A
Sbjct: 983  TGQAPPAPAKSIPVKKETKAPAAEK----LEPKA 1012



 Score = 33.5 bits (75), Expect = 0.31
 Identities = 27/101 (26%), Positives = 39/101 (38%), Gaps = 5/101 (4%)

Query: 206  QSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPSAHSPAHTHF---TLTLAEAHTRALT 262
            +S  +++ A+    P P P P  PPP PP    P   SP  T      LT+A   T A  
Sbjct: 2395 RSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATP 2454

Query: 263  PARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAP--VPS 301
                    +   ++         + +   PP PP P  +PS
Sbjct: 2455 LFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPS 2495



 Score = 32.0 bits (71), Expect = 0.91
 Identities = 47/217 (21%), Positives = 66/217 (30%), Gaps = 64/217 (29%)

Query: 93  AGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLPASEAPGLR 152
           A A  P +  + QP   + P Q  G  +  A  TG  P + P +L      PA   P   
Sbjct: 431 AKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTG--PTKPPSQLPG----PAKPPP--- 481

Query: 153 PDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQPPPMLSPGLAQSPGVEL 212
                                 P PA                +PPP   PG A+ P  + 
Sbjct: 482 --------------------QQPGPA----------------KPPPQ-QPGSAKPPSQQ- 503

Query: 213 HARTLSLPAPSPAPCLPPPAPPAARTPSAHSPAHTHFTLTLAEAHTRALTPARGGGEGDP 272
              +   P   P P  P P  P +  P +  P         A+   +  +PA+   +   
Sbjct: 504 -PGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGS-------AKPSAQQPSPAKPSAQQST 555

Query: 273 GPIVGGRPENEDSLASQTSPPAPPAPVPSTARARSPG 309
            P+         S      P  PP   PS  +  S G
Sbjct: 556 KPV---------SQTGSGKPLQPPTVSPSAKQPPSQG 583


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 52/222 (23%), Positives = 82/222 (36%), Gaps = 43/222 (19%)

Query: 95  AQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPD 154
           ++QP  + LAQPPG      VG  P ++      P   +PP        P ++ PGL+  
Sbjct: 383 SEQPGPKALAQPPG------VGKTPAQQ------PGPAKPPTQQVGTPKPLAQQPGLQ-S 429

Query: 155 SARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHA 214
            A+     +    +   G  PA  AG  +    +  P     PP   PG A+ P  +   
Sbjct: 430 PAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPT---KPPSQLPGPAKPPPQQ--- 483

Query: 215 RTLSLPAPSPAPCLPPPAPPAARTPSAHSPAHTHFTLTLAEAHTRALTPARGGGEGDPGP 274
                    P P  PPP  P +  P +  P  T               P +  G   P P
Sbjct: 484 ---------PGPAKPPPQQPGSAKPPSQQPGSTK-------------PPPQQPGPAKPSP 521

Query: 275 IVGG--RPENEDSLASQTSPPAPPAPVPSTARARSPGARRGA 314
              G  +P ++   +++ S   P    PS  ++  P ++ G+
Sbjct: 522 QQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGS 563



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 68/302 (22%), Positives = 102/302 (33%), Gaps = 81/302 (26%)

Query: 39  IPRESGIQKAHTRSPAQYSQTRLRRRRQGAVIVGRRRACPGRG---RGGLPGAAALGAGA 95
           + +E G  +   + P Q    +   ++QG          PGR    + G P + +    +
Sbjct: 196 VQKEQGKPEGIIKPPLQQQPPKPIPKQQG----------PGRDPLQQDGTPKSIS----S 241

Query: 96  QQPRRRRLAQPPGSRAPLQ------------------VGGAPRRRAHLTGG-------PP 130
           QQP + + +QPPG+  P+Q                        ++A +  G       P 
Sbjct: 242 QQPEKIK-SQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPS 300

Query: 131 RRRPPRLAAAHGLPASEAPG---LRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCT 187
             +PP      G P ++ PG    +P  A+                PPA  +GL      
Sbjct: 301 PSKPPIQQPTPGKPPAQQPGHEKSQPGPAK----------------PPAQPSGL------ 338

Query: 188 RLRPLLLQPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPSAHSPAHT 247
             +PL  QP  +  P   Q PG      T   PA    P  PP     +  PS+  P   
Sbjct: 339 -TKPLAQQPGTVKPP--VQPPG------TTKPPAQPLGPAKPPAQQTGSEKPSSEQPG-- 387

Query: 248 HFTLTLAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAPVPSTARARS 307
                LA+      TPA+  G   P     G P+         SP   P P  +  +   
Sbjct: 388 --PKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPG 445

Query: 308 PG 309
           PG
Sbjct: 446 PG 447



 Score = 33.5 bits (75), Expect = 0.31
 Identities = 47/214 (21%), Positives = 76/214 (35%), Gaps = 45/214 (21%)

Query: 130  PRRRPPRLAAAHGLPASEAPGLR----------PDSARTRLRLRLASARLPRGLPPAPAA 179
            PR        +H  P+SE+ G +          P  A+T++  +  +  +P+G P  P  
Sbjct: 822  PRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGP 881

Query: 180  GLWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTP 239
                      RP   Q  P  +P  +  P  +    +L+L + + AP   P  P    T 
Sbjct: 882  ----------RPTAGQTVP--TPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTG 929

Query: 240  SAHSPAHTHFTLTLAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQT--------- 290
                   + F+    +A     T  + G     GP   G P  +    SQ          
Sbjct: 930  KLFGFGASIFS----QASNLISTAGQPGPHSQSGP---GAPMKQAPAPSQPPTSQGPPKS 982

Query: 291  ---SPPAPPAPVPSTARARSPGARRGARELAPRA 321
               +PPAP   +P     ++P A +    L P+A
Sbjct: 983  TGQAPPAPAKSIPVKKETKAPAAEK----LEPKA 1012



 Score = 33.5 bits (75), Expect = 0.31
 Identities = 27/101 (26%), Positives = 39/101 (38%), Gaps = 5/101 (4%)

Query: 206  QSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPSAHSPAHTHF---TLTLAEAHTRALT 262
            +S  +++ A+    P P P P  PPP PP    P   SP  T      LT+A   T A  
Sbjct: 2395 RSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATP 2454

Query: 263  PARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAP--VPS 301
                    +   ++         + +   PP PP P  +PS
Sbjct: 2455 LFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPS 2495



 Score = 32.0 bits (71), Expect = 0.91
 Identities = 47/217 (21%), Positives = 66/217 (30%), Gaps = 64/217 (29%)

Query: 93  AGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLPASEAPGLR 152
           A A  P +  + QP   + P Q  G  +  A  TG  P + P +L      PA   P   
Sbjct: 431 AKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTG--PTKPPSQLPG----PAKPPP--- 481

Query: 153 PDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQPPPMLSPGLAQSPGVEL 212
                                 P PA                +PPP   PG A+ P  + 
Sbjct: 482 --------------------QQPGPA----------------KPPPQ-QPGSAKPPSQQ- 503

Query: 213 HARTLSLPAPSPAPCLPPPAPPAARTPSAHSPAHTHFTLTLAEAHTRALTPARGGGEGDP 272
              +   P   P P  P P  P +  P +  P         A+   +  +PA+   +   
Sbjct: 504 -PGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGS-------AKPSAQQPSPAKPSAQQST 555

Query: 273 GPIVGGRPENEDSLASQTSPPAPPAPVPSTARARSPG 309
            P+         S      P  PP   PS  +  S G
Sbjct: 556 KPV---------SQTGSGKPLQPPTVSPSAKQPPSQG 583


>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
          Length = 1497

 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 61/231 (26%), Positives = 74/231 (32%), Gaps = 44/231 (19%)

Query: 80  RGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAA 139
           RG  G PG   L     +P  +    P G          PR    LTG P  R PP  + 
Sbjct: 718 RGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQ----GPRGEQGLTGMPGIRGPPGPSG 773

Query: 140 AHGLPASEAP----GLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLR----- 190
             G P    P    GL     R  ++          G P AP   +   G + L      
Sbjct: 774 DPGKPGLTGPQGPQGLPGTPGRPGIK----------GEPGAPGKIVTSEGSSMLTVPGPP 823

Query: 191 --PLLLQPP-PMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPSAHSPAHT 247
             P  + PP P  +PG A   G+  H   L+L  P   P   P  PP    P    P   
Sbjct: 824 GPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPP--GPRGPPGPSIPGPPGPRG- 880

Query: 248 HFTLTLAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAP 298
                          P   G  G PGP       +E  L+    PP PP P
Sbjct: 881 ---------------PPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGP 916


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
            sapiens]
          Length = 1636

 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 71/252 (28%), Positives = 96/252 (38%), Gaps = 44/252 (17%)

Query: 107  PGSRAPLQVGGAPRRRAHLTG--------GPPRRRPPRLAAAHGLPASEAPGLRPDSART 158
            P S  P   G  P    +L+G        GP +   PR    H +P +  P L P  A T
Sbjct: 772  PPSPFPSSTGPGPH---YLSGPLPPGTYSGPTQLIQPRAPGPHAMPVAPGPALYPAPAYT 828

Query: 159  RLRLRLASARLPR-GLPPAPAAGLWRAGCTRLRPLLLQPPPMLS-PGLA----------Q 206
               L L     P+ G+  +P  G+  A    +  L   PPP  S P LA           
Sbjct: 829  P-ELGLVPRSSPQHGVVSSPYVGVGPA--PPVAGLPSAPPPQFSGPELAMAVRPATTTVD 885

Query: 207  SPGVELHARTLSLPAPSPA---PCLPPPAPPAARTPSAHSPAHTHFTLTLAEAHTRALTP 263
            S    + + T   P P+PA   PC P P P    TP  + PA     +  A+ H  +  P
Sbjct: 886  SIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTY-PAGAKQPIP-AQHHFSSGIP 943

Query: 264  ARGGGEGDPGPIVGGR----PENEDSLASQTSPPAPPAPV--PSTARARSPG--ARRGAR 315
            A     G P P +G +    P+   S A    PP  P P+  P     ++PG    +   
Sbjct: 944  A-----GFPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPY 998

Query: 316  ELAPRAGRRRQP 327
              AP+ G   QP
Sbjct: 999  PYAPQPGVLGQP 1010



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 71/245 (28%), Positives = 89/245 (36%), Gaps = 63/245 (25%)

Query: 85   LPGAAALGAGAQQP----RRRRLAQPPGSRAPLQVGGAPRRR-----AHLTGGPPRRRPP 135
            LP      AGA+QP           P G  AP ++G  P+       +   G  P ++P 
Sbjct: 918  LPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAP-RIGPQPQPHPQPHPSQAFGPQPPQQPL 976

Query: 136  RLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQ 195
             L   H  P  +APGL P  +                 P AP  G+           L Q
Sbjct: 977  PLQHPHLFPP-QAPGLLPPQSP---------------YPYAPQPGV-----------LGQ 1009

Query: 196  PPP----MLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPSAHSPAHTHFTL 251
            PPP     L PG AQ P   L A + +LP PSP P  PP        P A+ PA +    
Sbjct: 1010 PPPPLHTQLYPGPAQDP---LPAHSGALPFPSPGPPQPP------HPPLAYGPAPS---- 1056

Query: 252  TLAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAPVPSTARARSPG-- 309
                  TR + P +       GP   G+      L    +P   P PVP    A  P   
Sbjct: 1057 ------TRPMGP-QAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVPPRPPAAEPPPC 1109

Query: 310  ARRGA 314
             RRGA
Sbjct: 1110 LRRGA 1114



 Score = 38.1 bits (87), Expect = 0.013
 Identities = 56/214 (26%), Positives = 74/214 (34%), Gaps = 34/214 (15%)

Query: 88   AAALGAGAQQPRRRRLAQPPGSRAPLQVGGA-------PRRRAHLTGGPPRRRPPRLAAA 140
            ++ + AG   PR     QP     P Q  G        P +  HL    P + P  L   
Sbjct: 939  SSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLF---PPQAPGLLPPQ 995

Query: 141  HGLPASEAPGLR---PDSARTRLRLRLASARLPR----------GLPPAPAAGLWRAGCT 187
               P +  PG+    P    T+L    A   LP           G P  P   L      
Sbjct: 996  SPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPAP 1055

Query: 188  RLRPLLLQPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPSAHSPAHT 247
              RP+  Q  P+   G + +         +  PAPSP P   PP PPAA  P        
Sbjct: 1056 STRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVPPRPPAAEPPPC------ 1109

Query: 248  HFTLTLAEAHTRALTP-ARGGGEGDPGPIVGGRP 280
                  A A   + +P ++ GG   PG   GG+P
Sbjct: 1110 -LRRGAAAADLLSSSPESQHGGTQSPG---GGQP 1139


>gi|157785645 SPEG complex locus [Homo sapiens]
          Length = 3267

 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 99/369 (26%), Positives = 128/369 (34%), Gaps = 85/369 (23%)

Query: 20   GPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTRLRRRRQGAVIVGRR----- 74
            G SA S +P   P  +  G+ + + ++    RSP+    TRL R   G     +R     
Sbjct: 2013 GSSAESALPRAGPRELGRGLHKAASVELPQRRSPSP-GATRLARGGLGEGEYAQRLQALR 2071

Query: 75   ----RACPGRGR-GGLPGAA--ALGAGAQQPRRRRLA--------QPPGSRAPLQV---- 115
                R  P  G+  GL G    +LG  A+ PR  R A        QPP     LQ     
Sbjct: 2072 QRLLRGGPEDGKVSGLRGPLLESLGGRARDPRMARAASSEAAPHHQPPLENRGLQKSSSF 2131

Query: 116  --GGAPRRRAHLTGGPPRRRP------------PRLAA-AHGLPASEAPGLRPDSARTRL 160
              G A  R  H   G P   P            P L+A +   P+S A    P  +  + 
Sbjct: 2132 SQGEAEPRGRHRRAGAPLEIPVARLGARRLQESPSLSALSEAQPSSPARPSAPKPSTPKS 2191

Query: 161  RLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQ---PPPMLSPGLA----------QS 207
                A+       PPAP     +A   R  P+      PPP     LA          QS
Sbjct: 2192 AEPSATTPSDAPQPPAPQPAQDKAPEPRPEPVRASKPAPPPQALQTLALPLTPYAQIIQS 2251

Query: 208  PGVELHARTLS----LPAPSPAP--------CLPPPAPPAARTPSAHSPAHTHFTLTLAE 255
              +  HA+  S     P   P P          PPP  P  R PSA  P        LAE
Sbjct: 2252 LQLSGHAQGPSQGPAAPPSEPKPHAAVFARVASPPPGAPEKRVPSAGGPP------VLAE 2305

Query: 256  AHTRALTPARGGGEGDPGPIVGGRPENEDSLA--------SQTSPPAPPAPVPSTARARS 307
                   P R      PG  +    EN +S A        S+ SP +    + S +R+  
Sbjct: 2306 KARVPTVPPR------PGSSLSSSIENLESEAVFEAKFKRSRESPLSLGLRLLSRSRSEE 2359

Query: 308  PGARRGARE 316
             G  RGA E
Sbjct: 2360 RGPFRGAEE 2368



 Score = 35.4 bits (80), Expect = 0.083
 Identities = 78/310 (25%), Positives = 104/310 (33%), Gaps = 41/310 (13%)

Query: 17  WALGPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTRLRRRRQGAVIVGRRRA 76
           W     A S   P+      WG P   G  +   R+P   ++ R   +++ A +  R R 
Sbjct: 427 WVPLRKARSLEQPKSERGAPWGTP---GASQEELRAPGSVAERRRLFQQKAASLDERTRQ 483

Query: 77  CPGRGRGGLPGAAALGAGAQQPRRRRLAQPPGS-RAPLQVGGAPRRRAHLTGGPPRRRPP 135
                   L  A  LG   +   R  L +   S RA LQ   +PR             PP
Sbjct: 484 RSPASDLELRFAQELGRIRRSTSREELVRSHESLRATLQRAPSPREPGE---------PP 534

Query: 136 RLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQ 195
             +             RP + +T   +  A+A+     PP+P++   + G    RP    
Sbjct: 535 LFS-------------RPSTPKTSRAVSPAAAQ-----PPSPSSAE-KPGDEPGRPRSRG 575

Query: 196 PPPMLSPGLAQSPGVELHARTLSLPAPSPA--PCLPPPAPPAARTPSAHSPAHTHFTLTL 253
           P     PG  + P  E+  R       S A   C  P  PPAA  P A + A        
Sbjct: 576 PAGRTEPG--EGPQQEVRRRDQFPLTRSRAIQECRSPVPPPAADPPEARTKAPPGRKREP 633

Query: 254 AEAHTRALTPARGGGEGDPGPIV----GGRPENEDSLASQTSPPAPPAPVPSTARARSPG 309
                R L  A  G EG   P         PE E  L        P  P      ARS G
Sbjct: 634 PAQAVRFLPWATPGLEGAAVPQTLEKNRAGPEAEKRLRRGPEEDGPWGPWDRRG-ARSQG 692

Query: 310 ARRGARELAP 319
             R AR  +P
Sbjct: 693 KGRRARPTSP 702



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 46/170 (27%), Positives = 56/170 (32%), Gaps = 31/170 (18%)

Query: 193 LLQPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPSAHSPAHTHFTLT 252
           L +  P L P LA         R  + P PS +  LPPP+P   +      PA    T T
Sbjct: 279 LRREEPDLQPQLASEA-----PRRPAQPPPSKSALLPPPSPRVGKRSPPGPPAQPAATPT 333

Query: 253 LAEAHTRALTPA----------RGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAPVPST 302
               H R   P           RG      GP + G  E      S+   P   A    +
Sbjct: 334 --SPHRRTQEPVLPEDTTTEEKRGKKSKSSGPSLAGTAE------SRPQTPLSEASGRLS 385

Query: 303 ARARSPGARRGARELAPRAGRRRQPSGRTSWRRRARREQRDREPAVCGAW 352
           A  RSP           RAG R     +    RR   E+ D  PA    W
Sbjct: 386 ALGRSP--------RLVRAGSRILDKLQFFEERRRSLERSDSPPAPLRPW 427



 Score = 33.9 bits (76), Expect = 0.24
 Identities = 85/321 (26%), Positives = 107/321 (33%), Gaps = 74/321 (23%)

Query: 79  GRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLA 138
           G G+  L   A  G G      RRL   PGS    Q  GA  R  HL G  P  R  R  
Sbjct: 189 GSGQTVLEQEAGSGGGT-----RRL---PGSPRQAQATGAGPR--HL-GVEPLVRASRAN 237

Query: 139 AAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQPPP 198
                  SE      DS      L  ++  L RG   +    + ++G  R  P L    P
Sbjct: 238 LVGASWGSE------DSLSVASDLYGSAFSLYRGRALSIHVSVPQSGLRREEPDL---QP 288

Query: 199 MLSPGLAQSPGVELHARTLSLPAPSP-APCLPPPAPPAARTPSAHSPAHTHFTLTLAEAH 257
            L+    + P     +++  LP PSP      PP PPA    +  SP        L E  
Sbjct: 289 QLASEAPRRPAQPPPSKSALLPPPSPRVGKRSPPGPPAQPAATPTSPHRRTQEPVLPEDT 348

Query: 258 TRALTPARGGGEGDPGPIVGG----RP--------------------------------- 280
           T      RG      GP + G    RP                                 
Sbjct: 349 TTE--EKRGKKSKSSGPSLAGTAESRPQTPLSEASGRLSALGRSPRLVRAGSRILDKLQF 406

Query: 281 --ENEDSLASQTSPPAPPAPVPSTARARS---PGARRGARELAPRAGRRR-QPSGRTSWR 334
             E   SL    SPPAP  P     +ARS   P + RGA    P A +   +  G  + R
Sbjct: 407 FEERRRSLERSDSPPAPLRPWVPLRKARSLEQPKSERGAPWGTPGASQEELRAPGSVAER 466

Query: 335 RRARREQ--------RDREPA 347
           RR  +++        R R PA
Sbjct: 467 RRLFQQKAASLDERTRQRSPA 487



 Score = 32.7 bits (73), Expect = 0.54
 Identities = 52/212 (24%), Positives = 77/212 (36%), Gaps = 30/212 (14%)

Query: 108  GSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASA 167
            G++    V  A  + A +T  P R RPP        P S AP L P +A T   + ++ +
Sbjct: 2770 GTQDSSAVPSAAHQEAPVTSRPARARPP------DSPTSLAPPLAP-AAPTPPSVTVSPS 2822

Query: 168  RLPRGLPPAPAAGLWRAGCTRLRPLLLQPPPMLSP----GLAQSPGVELHARTLSLPAPS 223
              P   PP+ A    +A         + PPP   P    GL  +   E    +  +    
Sbjct: 2823 SPP--TPPSQALSSLKA---------VGPPPQTPPRRHRGLQAARPAEPTLPSTHVTPSE 2871

Query: 224  PAP-CLPPPAPPAARTPSAHSPAHTHFTLTLAEAHTRALTPARGGGEGDPGP------IV 276
            P P  L    P  A TP    P  +   + +  +   A  PA      +P P      + 
Sbjct: 2872 PKPFVLDTGTPIPASTPQGVKPVSSSTPVYVVTSFVSA-PPAPEPPAPEPPPEPTKVTVQ 2930

Query: 277  GGRPENEDSLASQTSPPAPPAPVPSTARARSP 308
               P  E   +  +SP + P P  +T R   P
Sbjct: 2931 SLSPAKEVVSSPGSSPRSSPRPEGTTLRQGPP 2962



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 52/224 (23%), Positives = 70/224 (31%), Gaps = 28/224 (12%)

Query: 97   QPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSA 156
            +P R R    P S AP     AP   +          PP  A +        P   P   
Sbjct: 2790 RPARARPPDSPTSLAPPLAPAAPTPPSVTVSPSSPPTPPSQALSSLKAVGPPPQTPPRRH 2849

Query: 157  RTRLRLRLASARLPRG--LPPAPAAGLWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHA 214
            R     R A   LP     P  P   +   G     P+    P  + P  + +P   + +
Sbjct: 2850 RGLQAARPAEPTLPSTHVTPSEPKPFVLDTGT----PIPASTPQGVKPVSSSTPVYVVTS 2905

Query: 215  RTLSLPAPSPAPCLPPPAPPAARTPSAHSPAHTHFTLTLAEAHTRALTPARGGGEGDPGP 274
               + PAP P    PPP P                     +   ++L+PA+      PG 
Sbjct: 2906 FVSAPPAPEPPAPEPPPEP--------------------TKVTVQSLSPAK-EVVSSPGS 2944

Query: 275  IVGGRPENEDSLASQTSPPAPPAPVPSTARARSPGARRGARELA 318
                 P  E +   Q  P  P   +   AR R  G  R  RE A
Sbjct: 2945 SPRSSPRPEGTTLRQGPPQKPYTFLEEKARGRF-GVVRACRENA 2987



 Score = 28.9 bits (63), Expect = 7.7
 Identities = 62/254 (24%), Positives = 82/254 (32%), Gaps = 45/254 (17%)

Query: 110  RAPLQVGGAPRRRA-------HLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRL 162
            RAP Q   AP   A          G  PRR   R  ++     S  P   P      L  
Sbjct: 1978 RAPSQDQEAPSPEALPSPGQEPAAGASPRRGELRRGSS---AESALPRAGPRELGRGLH- 2033

Query: 163  RLASARLPRGLPPAPAA----------GLWRAGCTRLRPLLLQPPP-------MLSPGLA 205
            + AS  LP+   P+P A          G +      LR  LL+  P       +  P L 
Sbjct: 2034 KAASVELPQRRSPSPGATRLARGGLGEGEYAQRLQALRQRLLRGGPEDGKVSGLRGPLLE 2093

Query: 206  QSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPSAHSPAHTHFTLTLAEAHTRALTPAR 265
               G     R     +   AP   PP        S+        + +  EA  R      
Sbjct: 2094 SLGGRARDPRMARAASSEAAPHHQPPLENRGLQKSS--------SFSQGEAEPRGRHRRA 2145

Query: 266  GGGEGDPGPIVGGRPENED------SLASQTSPPAPPAPVPSTARARSPGARR---GARE 316
            G     P   +G R   E       S A  +SP  P AP PST ++  P A       + 
Sbjct: 2146 GAPLEIPVARLGARRLQESPSLSALSEAQPSSPARPSAPKPSTPKSAEPSATTPSDAPQP 2205

Query: 317  LAPRAGRRRQPSGR 330
             AP+  + + P  R
Sbjct: 2206 PAPQPAQDKAPEPR 2219


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 76/331 (22%), Positives = 119/331 (35%), Gaps = 38/331 (11%)

Query: 40   PRESGIQKAHTRSPAQYSQTRLRRRRQGAVIVGRRRACPGRGRGGLPGAAALGAG----- 94
            P+  G+Q++ +RS  + ++T  RR R G+     RR    R R  +      G+G     
Sbjct: 1765 PKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRS 1824

Query: 95   ---------AQQPRRRRLAQPPGS--RAPLQVGGAPRRRAHLTGGP-----PRRRPPRLA 138
                     + + RR R   PP S  R+  +   AP +R+     P      R R P ++
Sbjct: 1825 PARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLIS 1884

Query: 139  AAHGLPASEAPGLRPDSARTRLRLRLASARL---------PRGLPPAPAAGLWRAGCTRL 189
                   +     R   +RT +  R + +R           R  P        R   TR 
Sbjct: 1885 RRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRR 1944

Query: 190  RPLLLQPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPSAHSPAHTHF 249
            R     PP       +++P V    R+ S  +P           P  R  S    +    
Sbjct: 1945 RSRSRTPPVTRRRSRSRTPPV-TRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTS---- 1999

Query: 250  TLTLAEAHTRALTPARGGGEGDPGPIVGGRPENEDS-LASQTSPPAPPAPVPSTARARSP 308
             +T   + +R     R        P +  R  +    L  + S    P  +   +R+R+P
Sbjct: 2000 PVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTP 2059

Query: 309  GARRGAREL--APRAGRRRQPSGRTSWRRRA 337
               RG R L  +P A RRR  SG +S R R+
Sbjct: 2060 RTARGKRSLTRSPPAIRRRSASGSSSDRSRS 2090



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 79/300 (26%), Positives = 103/300 (34%), Gaps = 77/300 (25%)

Query: 47  KAHTRSPAQYSQTRLR----RRRQGAVIVGRRRACPGRGRGGLPGAAALGAGAQQPRRRR 102
           ++ +R+P +   +R R    RR + A   GR R+   RGR   P            RR R
Sbjct: 494 RSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGR 553

Query: 103 LAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRL 162
                 SR+  +  G    R+  T G  R R P   A  G   S  P      AR R R 
Sbjct: 554 ------SRSARR--GRSHSRSPATRGRSRSRTP---ARRGRSRSRTP------ARRRSRS 596

Query: 163 RLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARTLSLPAP 222
           R  + R  R   PA      R G +R R          +P   +S       RT S    
Sbjct: 597 RTPTRRRSRSRTPA------RRGRSRSR----------TPARRRS-------RTRS---- 629

Query: 223 SPAPCLPPPAPPAARTPSAHSPAHTHFTLTLAEAHTRALTPARGGGEGDPGPIVGGRPEN 282
                      P  R   + SPA            +R+ TPAR G      P   GR  +
Sbjct: 630 -----------PVRRRSRSRSPARR-------SGRSRSRTPARRGRSRSRTPARRGRSRS 671

Query: 283 EDSLASQTSPPAPPAPVPSTARARSPGARRGARELAPRAGRRRQPSGRTSWRRRARREQR 342
                        PA     +R+R+P  R  +R   PR GR R  S     R  +R  QR
Sbjct: 672 RT-----------PARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQR 720



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 80/329 (24%), Positives = 112/329 (34%), Gaps = 78/329 (23%)

Query: 46   QKAHTRSPAQYSQTRLRRRRQGAVIVGRRRACPG----RGRGGLPGAAALGAGAQQP--- 98
            +++ +R+P      R   R   A+   RRR+  G    R R   P A    +G++ P   
Sbjct: 2052 RRSRSRTPRTARGKRSLTRSPPAI---RRRSASGSSSDRSRSATPPATRNHSGSRTPPVA 2108

Query: 99   ----RRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLPASEAPGLR-P 153
                R    ++P  S  PL    +P     L      R P  +    G    + PG R P
Sbjct: 2109 LNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSS---RTPMSVLQQAGGSMMDGPGPRIP 2165

Query: 154  DSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELH 213
            D  RT +    A +R+        A  L        RP    PP M + GLA        
Sbjct: 2166 DHQRTSVPENHAQSRI--------ALALTAISLGTARP----PPSMSAAGLA-------- 2205

Query: 214  ARTLSLPAPSPAPCL--PPPAPPAARTPSAHSPAHTHFTLTLAEAHTRAL---------- 261
            AR   +PAP P   L   P A  A+R P+A + A     + LA A T A+          
Sbjct: 2206 ARMSQVPAPVPLMSLRTAPAANLASRIPAASAAA-----MNLASARTPAIPTAVNLADSR 2260

Query: 262  TPARGGGEGDPGP-----------------------IVGGRPENEDSLASQTSPPAPPAP 298
            TPA         P                       + G R     +  S T    PP  
Sbjct: 2261 TPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTA 2320

Query: 299  VPSTARARSPGARRGARELAPRAGRRRQP 327
                + +R+P A   A  + PR+     P
Sbjct: 2321 ANYPSSSRTPQAPASANLVGPRSAHATAP 2349



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 86/373 (23%), Positives = 123/373 (32%), Gaps = 48/373 (12%)

Query: 11  SSAFMTWALGPSAYSKIPPRLPIRMTW---------GIPRESGIQKAHTRSPA----QYS 57
           S +   W    S   +   R P R  W         G  R +   ++H+RSPA      S
Sbjct: 516 SRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRS 575

Query: 58  QTRLRRRRQGAVIVGRRRA-----CPGRGRGGLPGAAALGAGAQQPRRRRLAQPP----- 107
           +T  RR R  +    RRR+        R R   P            RRR   + P     
Sbjct: 576 RTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRS 635

Query: 108 GSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASA 167
            SR+P +  G  R R     G  R R P   A  G   S  P  R   +R+R       A
Sbjct: 636 RSRSPARRSGRSRSRTPARRGRSRSRTP---ARRGRSRSRTPARRSGRSRSR-----TPA 687

Query: 168 RLPRGLPPAPAAGLWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARTLSLPAPS-PAP 226
           R  R     P  G  R+     R       P        S   +  +RT    + S  +P
Sbjct: 688 RRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSP 747

Query: 227 CLPPPAPPAARTPSAHSP---AHTHFTLTLAEAHT------RALTPARGGGEGDPGPIVG 277
            +      + R+ S  SP   A +  +L  + + +      ++ TP R    G   P   
Sbjct: 748 EMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAK 807

Query: 278 GRPENEDSLASQTSPPAPPAPVPS----TARARSPGARRGARELAPRAGRRRQPSGRTSW 333
            R     S +S + PP   +  PS    ++ +  P  + G     PR G    P      
Sbjct: 808 SRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGT---PPRQGSITSPQANEQS 864

Query: 334 RRRARREQRDREP 346
               RR   +  P
Sbjct: 865 VTPQRRSCFESSP 877



 Score = 37.7 bits (86), Expect = 0.017
 Identities = 78/308 (25%), Positives = 106/308 (34%), Gaps = 49/308 (15%)

Query: 99   RRRRLAQPPGSRAPLQVGGAP--RRRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSA 156
            RR R    P +R   +   +P  RRR+     P  RR  R +    LP   +    P + 
Sbjct: 1992 RRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSR-SRTPLLPRKRSRSRSPLAI 2050

Query: 157  RTRLRLRLA-SARLPRGLPPAPAAGLWRA--GCTRLRPLLLQPPPMLSPGLAQSPGVELH 213
            R R R R   +AR  R L  +P A   R+  G +  R     PP   +   +++P V L+
Sbjct: 2051 RRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALN 2110

Query: 214  ARTLSL---PAPSPAPCLPPPAPPAARTPSAHSPAHTHFTLTLAEAHTRALTPARGGGEG 270
            +  +S    P+ SP P          R+P    P      L  +      L  A G    
Sbjct: 2111 SSRMSCFSRPSMSPTPL------DRCRSPGMLEP------LGSSRTPMSVLQQAGGSMMD 2158

Query: 271  DPGPIVGGR-----PENED-----------SLASQTSPPAP------------PAPVPST 302
             PGP +        PEN             SL +   PP+             PAPVP  
Sbjct: 2159 GPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLM 2218

Query: 303  ARARSPGARRGARELAPRAGRRRQPSGRTSWRRRARREQRDREPAVCGAWPRGSHAAGAG 362
            +   +P A   +R  A  A      S RT     A      R PA   A    S      
Sbjct: 2219 SLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVA 2278

Query: 363  WTAVAAGD 370
             +AV   D
Sbjct: 2279 PSAVNLAD 2286



 Score = 37.0 bits (84), Expect = 0.028
 Identities = 66/309 (21%), Positives = 114/309 (36%), Gaps = 23/309 (7%)

Query: 46  QKAHTRSPAQYSQTRLRRRRQGAVIVGRRRACPGRGRGGLPGAAALGAGAQQPRRRRLAQ 105
           + + +RSP    + + +++ +G        + P R R          + ++  +R+  + 
Sbjct: 176 ESSSSRSPTPKQKKKKKKKDRGR---RSESSSPRRERKKSSKKKKHRSESESKKRKHRSP 232

Query: 106 PPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLA 165
            P S+   +     R R+  T  P  RR  R  +A    +S+    R  SA  +      
Sbjct: 233 TPKSKRKSKDKKRKRSRS-TTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTAL 291

Query: 166 SARLP------RGLPPAPAAGLWRAGCTRL-RPLLLQPPPMLSPGLAQSPGVELHARTLS 218
           + R P      RG   AP +     G T   RP   +          +    +   ++ +
Sbjct: 292 AGRSPSPASGRRGEGDAPFS---EPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSAT 348

Query: 219 LPAPSPAPCLPPPAPPAARTPSAHSPAHTHFTLTLAEAHTRALTP-ARGGGEGDPGPIVG 277
            P+PSP      P PPA     A     +   L         + P +      D  P   
Sbjct: 349 RPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSP--- 405

Query: 278 GRPENEDSLA-SQTSPPAPPAPVPSTARARSPGARRGARELAPRAGRRRQ-PSGRTSWRR 335
             P++ + L  S +S  +PP+P P T  +R   +   + + AP  G  R+  S  TS  R
Sbjct: 406 --PKSPEKLPQSSSSESSPPSPQP-TKVSRHASSSPESPKPAPAPGSHREISSSPTSKNR 462

Query: 336 RARREQRDR 344
              R +RD+
Sbjct: 463 SHGRAKRDK 471



 Score = 35.4 bits (80), Expect = 0.083
 Identities = 86/359 (23%), Positives = 119/359 (33%), Gaps = 72/359 (20%)

Query: 52   SPAQYSQTRL--RRRRQGAV--IVGRRRACPGRGRGGLPGAAALGAGAQQ--PRRRRLAQ 105
            SP   S++RL  RR R G+   +  + RA P R + G   +    A A +  PRR R   
Sbjct: 1582 SPEVDSKSRLSPRRSRSGSSPEVKDKPRAAP-RAQSGSDSSPEPKAPAPRALPRRSRSGS 1640

Query: 106  PPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLA 165
                R P   G +       T   P   P    A  G  +S  P  +  +   R   R +
Sbjct: 1641 SSKGRGPSPEGSSS------TESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSS 1694

Query: 166  -----SARLPRGLPPAPAAGLWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARTLSLP 220
                  ARL R    A ++   R+   R  P   + P + SP  A+        R+ S P
Sbjct: 1695 PELTRKARLSRRSRSASSSPETRS---RTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSP 1751

Query: 221  ----------APSPAP-----CLPPPAPPAARTPSAHSPAHTHFTLTLAEAHTRA---LT 262
                      +PSP P               RT      + +  + +     +R+   +T
Sbjct: 1752 RTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVT 1811

Query: 263  PARGGGEG----DPGPIVGGRPENEDSLASQTSPPAP---------PAPVPSTARARSPG 309
              R GG G     P      R  +        +PP           PAP   +    SP 
Sbjct: 1812 RRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPA 1871

Query: 310  ARRGARELAPRAGRRRQPS-----------GRTSWRRR---------ARREQRDREPAV 348
              R +R   P   RRR  S            RTS  RR         +RR  R R P V
Sbjct: 1872 THRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPV 1930



 Score = 34.7 bits (78), Expect = 0.14
 Identities = 72/335 (21%), Positives = 117/335 (34%), Gaps = 34/335 (10%)

Query: 21   PSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTRLRRRRQGAVIVG--RRRACP 78
            P   S+ PPR               +++   SP    + RL RR + A      R R  P
Sbjct: 1678 PKTKSRTPPR---------------RRSSRSSPELTRKARLSRRSRSASSSPETRSRTPP 1722

Query: 79   GRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPR------RRAHLTGGPPRR 132
               R     +      ++  RRRR A  P ++   + G +P       +R+       + 
Sbjct: 1723 RHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKT 1782

Query: 133  RPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPL 192
            R  R     G   S +   +   +R+R+  R           PA      R    R R  
Sbjct: 1783 RTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESS-RTSSRRRRGR 1841

Query: 193  LLQPPPMLSPGLAQ-SPGVELHARTLSLPAP-----SPAPCLPPPAPPAARTPSAHSPAH 246
               PP       ++ SP     +R+ + PA      S  P +      +  +P +   + 
Sbjct: 1842 SRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSR 1901

Query: 247  THFTLTLAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAPVPSTARAR 306
            +  ++T   + +RA   +R        P+   R  +      + S    P      +R+R
Sbjct: 1902 SRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSR 1961

Query: 307  SPG-ARRGARELAPRAGRRRQPSGRTS--WRRRAR 338
            +P   RR +R       RRR  S RTS   RRR+R
Sbjct: 1962 TPPVTRRRSRSRTSPITRRRSRS-RTSPVTRRRSR 1995



 Score = 34.3 bits (77), Expect = 0.18
 Identities = 69/253 (27%), Positives = 95/253 (37%), Gaps = 56/253 (22%)

Query: 104  AQPPGSRAPLQVGGAPRRRAHLTGGPPR---RRPPRLAAAHGLPASEAPGLRPDSARTRL 160
            A+PP S   +   G   R + +    P    R  P    A  +PA+ A  +   SART  
Sbjct: 2193 ARPPPS---MSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPA 2249

Query: 161  ---RLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELH-ART 216
                + LA +R P     A AA    +  T + P  +    +  P    +P V L  ART
Sbjct: 2250 IPTAVNLADSRTPA----AAAAMNLASPRTAVAPSAVN---LADPRTPTAPAVNLAGART 2302

Query: 217  LSLPAPSPAPCL-----PPPA---PPAARTPSAHSPA--------HTHFTLTLAEAHTRA 260
               PA   A  L     PP A   P ++RTP A + A        H    + +A + T A
Sbjct: 2303 ---PAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAA 2359

Query: 261  -----------LTPARGGGEGDPGPI-------VGGR--PENEDSLASQTSPPAPPAPVP 300
                       + PA  G       +       V GR  P   D   S+T P AP     
Sbjct: 2360 ALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRM 2419

Query: 301  STARARSPGARRG 313
            ++ RA SP +R G
Sbjct: 2420 TSERAPSPSSRMG 2432



 Score = 33.9 bits (76), Expect = 0.24
 Identities = 39/153 (25%), Positives = 62/153 (40%), Gaps = 36/153 (23%)

Query: 219  LPAPSPAPC------LPPPAPPAAR-----------TPSAHSPAHTHFTLTLAEAHTRAL 261
            +P+P+PAP        PP   PA R           + S+ S + +  + + + + + + 
Sbjct: 2579 VPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2638

Query: 262  TPARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAPVPSTARARSP----GARRGAREL 317
            + +       P P   G      +L    SP  PP   P   R+RSP     + R +R L
Sbjct: 2639 SSSSSSSSSSPSPAKPG----PQALPKPASPKKPP---PGERRSRSPRKPIDSLRDSRSL 2691

Query: 318  APRAGRRRQPSGRTSWR--------RRARREQR 342
            +     RR+PS + S R        R +RR QR
Sbjct: 2692 SYSPVERRRPSPQPSPRDQQSSSSERGSRRGQR 2724


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 50/155 (32%), Positives = 52/155 (33%), Gaps = 59/155 (38%)

Query: 85  LPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLP 144
           +PG   LG     P R     PPG    L  G  P       G PP  RPP +       
Sbjct: 407 MPGPPPLGPPPAPPLR-----PPGPPTGLPPGPPP-------GAPPFLRPPGM------- 447

Query: 145 ASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQPPPMLSPGL 204
               PGLR                LPR LPP P  G         RP    PPP   PGL
Sbjct: 448 ----PGLR--------------GPLPRLLPPGPPPG---------RPP--GPPPGPPPGL 478

Query: 205 AQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTP 239
              P           P   P P LPPPAPP    P
Sbjct: 479 PPGP-----------PPRGPPPRLPPPAPPGIPPP 502



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 48/147 (32%), Positives = 51/147 (34%), Gaps = 51/147 (34%)

Query: 106 PPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLA 165
           PP S  P Q+   P     + G PP   PP            AP LRP            
Sbjct: 393 PPQSVPPSQIQAPP-----MPGPPPLGPPP------------APPLRPPGP--------- 426

Query: 166 SARLPRGLPPAPAAG----LWRAGCTRLR---PLLLQPPPMLSPGLAQSPGVELHARTLS 218
               P GLPP P  G    L   G   LR   P LL P P   PG  + PG         
Sbjct: 427 ----PTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGP--PPG--RPPG--------- 469

Query: 219 LPAPSPAPCLPPPAPPAARTPSAHSPA 245
            P P P P LPP  PP    P    PA
Sbjct: 470 -PPPGPPPGLPPGPPPRGPPPRLPPPA 495


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 73/248 (29%), Positives = 81/248 (32%), Gaps = 57/248 (22%)

Query: 129 PPRR-----RPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWR 183
           PPRR      PPR  A  G PA+ A    P +           A  P   PPAP A    
Sbjct: 101 PPRRGATPPAPPR--APRGAPAAAAAAAPPPTP----------APPP---PPAPVAAAAP 145

Query: 184 AGCTRLRPLLLQPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPSAHS 243
           A   R        PP  SPG AQ PG     R   L AP PAP  PP   P A    A  
Sbjct: 146 ARAPRAAAAAATAPP--SPGPAQ-PGPRAQ-RAAPLAAPPPAPAAPPAVAPPAGPRRAPP 201

Query: 244 PAHTHFTLTLAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAPVPSTA 303
           PA          A    L P                P+       Q  PP  P P P   
Sbjct: 202 PA--------VAAREPPLPPP---------------PQPPAPPQQQQPPPPQPQPPPEGG 238

Query: 304 RARSPGARR--GARELAPRAGRRRQPSGRTSWRR--------RARREQRDREPAVCGAWP 353
             R+ GA R    RE+    G      GR +  R         A R + +R      A P
Sbjct: 239 AVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALP 298

Query: 354 RGSHAAGA 361
           RG     A
Sbjct: 299 RGDRPGRA 306



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 74/294 (25%), Positives = 98/294 (33%), Gaps = 41/294 (13%)

Query: 28  PPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTRLRRRRQGAVIVGRRRACPGRGRGGLPG 87
           P R    +   I + + ++ ++  S +  +  R++  R+GA         P R   G P 
Sbjct: 66  PERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGAT-----PPAPPRAPRGAPA 120

Query: 88  AAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLPASE 147
           AAA  A            PP + AP      P   A +    P R P   AAA   P S 
Sbjct: 121 AAAAAA------------PPPTPAP------PPPPAPVAAAAPARAPRAAAAAATAPPSP 162

Query: 148 APGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRP--LLLQPPPMLSPGLA 205
            P      A+     R A    P   P AP A    AG  R  P  +  + PP+  P   
Sbjct: 163 GPAQPGPRAQ-----RAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQP 217

Query: 206 QSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPSAHSPAHTHFTLTLAEAHTRA---LT 262
            +P  +        P P P    PPP   A R   A  P      +        A   LT
Sbjct: 218 PAPPQQQQP-----PPPQPQ---PPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLT 269

Query: 263 PARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAPVPSTARARSPGARRGARE 316
             R  G  +      GR E     A        P   P  A AR   ++RG  E
Sbjct: 270 RGRVQGLLEEEAAARGRLERTRLGALALPRGDRPGRAPPAASARPSRSKRGGEE 323



 Score = 34.3 bits (77), Expect = 0.18
 Identities = 23/66 (34%), Positives = 27/66 (40%), Gaps = 2/66 (3%)

Query: 259 RALTPARGGGEGDPGPIVGGRPENEDSLASQTSP--PAPPAPVPSTARARSPGARRGARE 316
           R   P RG     P     G P    + A   +P  P PPAPV + A AR+P A   A  
Sbjct: 98  RVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAAT 157

Query: 317 LAPRAG 322
             P  G
Sbjct: 158 APPSPG 163


>gi|223972704 hypothetical protein LOC284418 [Homo sapiens]
          Length = 922

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 58/249 (23%), Positives = 88/249 (35%), Gaps = 21/249 (8%)

Query: 101 RRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRL 160
           ++L   P S      G AP ++A     PPR+ P   A +   PA  AP  +  +     
Sbjct: 420 QKLPAVPASSWKPPPGLAPPQKAPAASAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPS 479

Query: 161 RLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQPPPMLSPGLAQSPGVEL-----HAR 215
           R   A++  PR     PA            P    PP   +P +   P   +       +
Sbjct: 480 RKASAASASPRKASAVPAP-----------PQKTPPPSQKAPSVPTIPQKAVSPTAPKKK 528

Query: 216 TLSLPAPS--PAPCLPPPAPPAARTPSAHSPAHTHFTLTLAEAHTRALTPARGGGEGDPG 273
           +L LPAPS    P  P     A   P++       F +       RA+      G G P 
Sbjct: 529 SLLLPAPSQKALPTSPTEYQMALSPPASRGKLPGDFDVLPTGIPGRAVLERSQSG-GKPE 587

Query: 274 PIVGGRPENEDSLASQTSPPAPPAPVPSTARARSPGARRGARELAPRAGRRRQPSGRTSW 333
           P+V  R +  D +   T   +P +P   T +          +E+   A R +       W
Sbjct: 588 PVVTVRTQETDVVEMTTQAKSPESPFTVTKKESKDILISQTKEVTLEAFRGQ--GKLEDW 645

Query: 334 RRRARREQR 342
              A+ E+R
Sbjct: 646 AHWAKLEER 654



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 22/102 (21%), Positives = 42/102 (41%), Gaps = 3/102 (2%)

Query: 76  ACPGRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPP 135
           + P R    +P  +        P ++  A P  SR       +PR+ + +   PP++ PP
Sbjct: 446 SAPPRKAPAVPAPSQKAPAVPAPSQKAPAIPAPSRKASAASASPRKASAVP-APPQKTPP 504

Query: 136 RLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAP 177
               A  +P      + P + + +  L  A ++  + LP +P
Sbjct: 505 PSQKAPSVPTIPQKAVSPTAPKKKSLLLPAPSQ--KALPTSP 544


>gi|169167057 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 320

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 92/339 (27%), Positives = 115/339 (33%), Gaps = 76/339 (22%)

Query: 32  PIRMTWGIPRESGIQKAHTRSPAQYSQTRLRRRRQGAVIVGRRRACPGRGRGGLPGAAAL 91
           P+    G   +S I + H RSP                  GRR        G LP    L
Sbjct: 3   PLETNKGSIGQSAIPRFHLRSP------------------GRRGTA-----GNLPRRLPL 39

Query: 92  GAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLPASEAP-- 149
             G+  PR  R  +   S A +   GA           P    P L +     AS AP  
Sbjct: 40  AQGS--PRCCRFCKGSVSTATVTSSGA---------SAPGSADPTLGSTAARRAS-APWA 87

Query: 150 --GLRPDSARTRL-RLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQPPPMLSPGLAQ 206
               R DS    L RLR A+  L    P        R+ C    PL  +  P LSP    
Sbjct: 88  SLSTRADSGLRHLDRLRKAARLLFVNTPHV------RSPCPIRSPLPAREDPPLSPQHWG 141

Query: 207 SPGVELHARTLSLPAPSPA-------------PCLPPPAPPAARTP-----SAHSPAHTH 248
              ++   R     +  P              PC  PP PPA R+P      AH      
Sbjct: 142 GEILKFPPREKRASSAEPGHWEKRQDKRLETHPCRAPPLPPARRSPLPRAACAHPRRPRP 201

Query: 249 FTLTLAEAHTRALT---PARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAPVPSTARA 305
              T      R L+   P+  GG+  P P+V  R     +   Q +P A    V    R 
Sbjct: 202 LAGTTFCGGARVLSNPPPSGSGGDARPSPLVPRRCRATSASLPQETPFA--LSVVWAPRR 259

Query: 306 RSPGARRGARELAPRAGRRRQPSG-----RTSWRRRARR 339
           RS G  RG R   P A  +R P+G      TSW   +RR
Sbjct: 260 RSQGDARGRRTGVPCA--KRPPAGWLAAAVTSWSPASRR 296


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 53/166 (31%), Positives = 60/166 (36%), Gaps = 21/166 (12%)

Query: 143  LPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAG------LWRAGCTRLRPLL--- 193
            LP    P L P +A  +      +  LP   PP P AG      L  AG   L PL    
Sbjct: 883  LPGMTVPTL-PSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAG 941

Query: 194  LQPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAP-PAARTPSAHSPAHTHFTLT 252
            + PPP L PG A  P   L    + LP P P   +PPP P P A  P             
Sbjct: 942  IPPPPPL-PGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPP---------P 991

Query: 253  LAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAP 298
            L  A      P  G G   P P+ G        L     PP PP P
Sbjct: 992  LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1037



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 60/222 (27%), Positives = 65/222 (29%), Gaps = 46/222 (20%)

Query: 78   PGRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRL 137
            PG G   LP     G     P       PP    PL   G P        G P   PP L
Sbjct: 927  PGAGILPLPPLPGAGIPPPPPLPGAAIPPP---PPLPGAGIPLPPPLPGAGIPP--PPPL 981

Query: 138  AAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQPP 197
              A   P    PG                A +P   PP P AG+              PP
Sbjct: 982  PGAGIPPPPPLPG----------------AGIPPP-PPLPGAGI--------------PP 1010

Query: 198  PMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAP-PAARTPSAHSPAHTHFTLTLAEA 256
            P   PG    P   L    +  P P P   +PPP P P A  P             L  A
Sbjct: 1011 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP---------PLPGA 1061

Query: 257  HTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAP 298
                  P  G G   P P+ G        L     PP PP P
Sbjct: 1062 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1103



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 35/126 (27%), Positives = 40/126 (31%), Gaps = 24/126 (19%)

Query: 174  PPAPAAGLWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAP 233
            PP P AG+              PPP   PG+   P   L    +  P P P   +PPP P
Sbjct: 1089 PPLPGAGI--------------PPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1134

Query: 234  -PAARTPSAHSPAHTHFTLTLAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSP 292
             P A  P             L         P  G G   P P+ G        L     P
Sbjct: 1135 LPGAGIPPPP---------PLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIP 1185

Query: 293  PAPPAP 298
            P PP P
Sbjct: 1186 PPPPLP 1191



 Score = 37.7 bits (86), Expect = 0.017
 Identities = 71/278 (25%), Positives = 88/278 (31%), Gaps = 49/278 (17%)

Query: 78   PGRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRL 137
            P  G G  P     GAG   P     A  P       VG  P       G PP   PP L
Sbjct: 1068 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPP---PPPL 1124

Query: 138  AAAHGLPASEAPG--LRPDSARTRLRLR----LASARLPRGLPPAPAAGLWRAGCTRLRP 191
              A   P    PG  + P     R+ +     L  A +P   PP P AG+          
Sbjct: 1125 PGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPP-PPLPGAGI---------- 1173

Query: 192  LLLQPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAP-PAARTPSAHSPAHTHFT 250
                PPP   PG+   P   L    +  P P P   +PPP P P    P A +P      
Sbjct: 1174 ----PPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPP----- 1224

Query: 251  LTLAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSPPAP-----PAPVPSTARA 305
                        P  G G   P  +    P     + S T P        P P+PS    
Sbjct: 1225 -----------LPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFG 1273

Query: 306  RSPGARRGARELAPRAGRRRQPSGRTSWRRRARREQRD 343
                  +G+R+      R  +P     W R     +RD
Sbjct: 1274 LGMNQDKGSRKQPIEPCRPMKP---LYWTRIQLHSKRD 1308



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 48/179 (26%), Positives = 64/179 (35%), Gaps = 13/179 (7%)

Query: 132 RRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAG--LWRAGCT-- 187
           R P +  +  GLP SEAP L       +      +   P   P   AAG  +  AG T  
Sbjct: 288 REPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDE 347

Query: 188 RLRPLLLQPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPSAHSPAHT 247
                  +  P  SPG   +P V   A    L          P AP AA  P + +P+  
Sbjct: 348 EGEEDAFEDAPRGSPGEEWAPEVGEDA-PQRLGEEPEEEAQGPDAPAAASLPGSPAPSQR 406

Query: 248 HF------TLTLAEAHTRALTPARGGGEGDP--GPIVGGRPENEDSLASQTSPPAPPAP 298
            F      T    +  TR L+         P   P +  RPE   S  S+T+  +  AP
Sbjct: 407 CFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKRRPEPSLSRGSRTALASVAAP 465


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 44/133 (33%), Positives = 53/133 (39%), Gaps = 20/133 (15%)

Query: 174 PPAPAAGLWR---AGCTRLRPLLLQPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPP 230
           PP P + + +   A C    P    PPP L     Q      H   ++ P P P P +P 
Sbjct: 718 PPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQ------HITQVAPPTPPPPPPIPA 771

Query: 231 PAPP-AARTPSAHSPAHTHFTLTLAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLAS- 288
           P PP A   P    PA T  T T+A   T+A  P        P P V    +     AS 
Sbjct: 772 PLPPQAPPKPLVTIPAPTS-TKTVAPVVTQAAPPT-------PTPPVPPAKKQPAFPASY 823

Query: 289 -QTSPPAPPAPVP 300
              SPP PP PVP
Sbjct: 824 IPPSPPTPPVPVP 836



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 41/131 (31%), Positives = 49/131 (37%), Gaps = 17/131 (12%)

Query: 187 TRLRPLLLQPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPSAHSPA- 245
           T L P L   P +++P  A  P   L       P P P P  PPP  P+   PSA S A 
Sbjct: 603 TSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAP 662

Query: 246 -----HTHFTLTLAEAHTRAL-----TPARGGGEGDPGPIVGGRPENEDSLASQTSPPAP 295
                 T   L  A  H+ AL      P        P  +V   P N         PP P
Sbjct: 663 MFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILV---PPNG---VVPPPPPPP 716

Query: 296 PAPVPSTARAR 306
           P P P +A A+
Sbjct: 717 PPPTPGSAMAQ 727



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 52/223 (23%), Positives = 76/223 (34%), Gaps = 35/223 (15%)

Query: 106  PPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLA 165
            PP    P+     P++++     PP    P  +    + +   P   P +  ++    + 
Sbjct: 828  PPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVP 887

Query: 166  SARLPRGLPPAPAAGLWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARTLSLPAPSPA 225
            +   P+  P   A   W+     + P    PPP     L   P           P PSP 
Sbjct: 888  ANVAPQSPPAVKAKPKWQPSSIPV-PSPDFPPPPPESSLVFPP-----------PPPSPV 935

Query: 226  PCLPPPAPP-AARTP-SAHSPAHTHFTLTLAEAHTRALTPAR------GGGEGDPGPIVG 277
            P  PPP PP A+ TP  + SP       +         TP R        G   P P   
Sbjct: 936  PAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEP--- 992

Query: 278  GRPENEDSLASQTSPPA-----------PPAPVPSTARARSPG 309
             +  + DSL S+ +PPA           PPA  P   +    G
Sbjct: 993  -KRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSG 1034



 Score = 35.4 bits (80), Expect = 0.083
 Identities = 47/198 (23%), Positives = 68/198 (34%), Gaps = 39/198 (19%)

Query: 167 ARLPRGLPPAPAAGLWRAGCTR-LRPLLLQ-----PPPMLSPGLAQS--PGVELHARTLS 218
           A LP   PP P   +     T+ + P++ Q     P P + P   Q   P   +     +
Sbjct: 771 APLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPT 830

Query: 219 LPAPSPAPCLP--------PPAPPAARTPSAHSPAHTHFTL--TLAEAHTRALTPARGGG 268
            P P P P LP        PP  P +  PS      + F    T     ++ L P     
Sbjct: 831 PPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANV 890

Query: 269 EGDPGPIVGGRPENEDSL--------------ASQTSPPAPPAPVPSTARARSPGARRGA 314
                P V  +P+ + S               +S   PP PP+PVP+      P A    
Sbjct: 891 APQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTA---- 946

Query: 315 RELAPRAGRRRQPSGRTS 332
              +P   +   P  +TS
Sbjct: 947 ---SPTPDKSGSPGKKTS 961



 Score = 34.7 bits (78), Expect = 0.14
 Identities = 29/113 (25%), Positives = 45/113 (39%), Gaps = 18/113 (15%)

Query: 193 LLQPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPSAHSPAHTHFTLT 252
           L +PP   +P + QS  V+     + +P     P  PPP PP   TP +           
Sbjct: 683 LFKPP---TPPVMQSQSVKPQ---ILVPPNGVVP--PPPPPPPPPTPGS----------A 724

Query: 253 LAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAPVPSTARA 305
           +A+       P+       P P+   + ++   +A  T PP PP P P   +A
Sbjct: 725 MAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQA 777


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.427 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,036,762
Number of Sequences: 37866
Number of extensions: 1534334
Number of successful extensions: 24434
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 286
Number of HSP's successfully gapped in prelim test: 1904
Number of HSP's that attempted gapping in prelim test: 13912
Number of HSP's gapped (non-prelim): 8362
length of query: 370
length of database: 18,247,518
effective HSP length: 104
effective length of query: 266
effective length of database: 14,309,454
effective search space: 3806314764
effective search space used: 3806314764
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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