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Search of human proteins with 116517226
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116517226 beta-defensin 135 [Homo sapiens]
(77 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116517226 beta-defensin 135 [Homo sapiens] 166 4e-42
gi|23503331 defensin, beta 123 precursor [Homo sapiens] 51 2e-07
gi|58865339 defensin, beta 121 [Homo sapiens] 50 3e-07
gi|82734223 beta-defensin 124 [Homo sapiens] 49 1e-06
gi|16905373 beta-defensin 118 [Homo sapiens] 39 0.001
gi|76563936 defensin, beta 125 preproprotein [Homo sapiens] 36 0.008
gi|22748611 defensin, beta 106A precursor [Homo sapiens] 35 0.010
gi|103485143 defensin, beta 106B precursor [Homo sapiens] 35 0.010
gi|21040279 defensin, beta 127 preproprotein [Homo sapiens] 35 0.013
gi|83582798 beta-defensin 115 [Homo sapiens] 34 0.029
gi|239757478 PREDICTED: defensin, beta 117 [Homo sapiens] 33 0.038
gi|239751980 PREDICTED: defensin, beta 117 [Homo sapiens] 33 0.038
gi|239746467 PREDICTED: defensin, beta 117 [Homo sapiens] 33 0.038
gi|83582802 beta-defensin 128 [Homo sapiens] 32 0.084
gi|37704382 defensin, beta 119 isoform a precursor [Homo sapiens] 32 0.084
gi|23503329 defensin, beta 119 isoform c precursor [Homo sapiens] 31 0.19
gi|46409558 beta-defensin 32 precursor [Homo sapiens] 31 0.25
gi|74136827 beta-defensin 134 [Homo sapiens] 30 0.42
gi|22748617 defensin, beta 105A precursor [Homo sapiens] 28 1.2
gi|149944551 defensin, beta 131 [Homo sapiens] 28 1.2
gi|103485141 defensin, beta 105B precursor [Homo sapiens] 28 1.2
gi|83582796 beta-defensin 113 [Homo sapiens] 27 2.7
gi|24797076 major histocompatibility complex, class II, DP beta ... 27 4.6
gi|239757284 PREDICTED: similar to Fc fragment of IgG binding pr... 27 4.6
gi|239753808 PREDICTED: hypothetical protein [Homo sapiens] 27 4.6
gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo ... 27 4.6
gi|239748372 PREDICTED: hypothetical protein [Homo sapiens] 27 4.6
gi|154146262 Fc fragment of IgG binding protein [Homo sapiens] 27 4.6
gi|134304840 KIAA0319 [Homo sapiens] 26 6.0
gi|83582800 beta-defensin 116 [Homo sapiens] 26 6.0
>gi|116517226 beta-defensin 135 [Homo sapiens]
Length = 77
Score = 166 bits (420), Expect = 4e-42
Identities = 77/77 (100%), Positives = 77/77 (100%)
Query: 1 MATRSVLLALVVLNLLFYVPPGRSGPNVYIQKIFASCWRLQGTCRPKCLKNEQYRILCDT 60
MATRSVLLALVVLNLLFYVPPGRSGPNVYIQKIFASCWRLQGTCRPKCLKNEQYRILCDT
Sbjct: 1 MATRSVLLALVVLNLLFYVPPGRSGPNVYIQKIFASCWRLQGTCRPKCLKNEQYRILCDT 60
Query: 61 IHLCCVNPKYLPILTGK 77
IHLCCVNPKYLPILTGK
Sbjct: 61 IHLCCVNPKYLPILTGK 77
>gi|23503331 defensin, beta 123 precursor [Homo sapiens]
Length = 67
Score = 50.8 bits (120), Expect = 2e-07
Identities = 26/67 (38%), Positives = 33/67 (49%), Gaps = 10/67 (14%)
Query: 6 VLLALVVLNLLFYVPPGRSGPNVYIQKIFASCWRLQGTCRPKCLKNEQYRILCDTIHLCC 65
+LL L VL LL + PG + CW L G CR +C K E+ + C +CC
Sbjct: 4 LLLTLTVLLLLSQLTPGGT----------QRCWNLYGKCRYRCSKKERVYVYCINNKMCC 53
Query: 66 VNPKYLP 72
V PKY P
Sbjct: 54 VKPKYQP 60
>gi|58865339 defensin, beta 121 [Homo sapiens]
Length = 76
Score = 50.4 bits (119), Expect = 3e-07
Identities = 27/68 (39%), Positives = 33/68 (48%), Gaps = 12/68 (17%)
Query: 6 VLLALVVLNLLFYVPPGRSGPNVYIQKIFASCWRLQGTCRPKCLKNEQYRILCDTIHLCC 65
+LL L V LL V P CW G CR C ++E Y ILC T CC
Sbjct: 4 LLLLLTVTLLLAQVTP------------VMKCWGKSGRCRTTCKESEVYYILCKTEAKCC 51
Query: 66 VNPKYLPI 73
V+PKY+P+
Sbjct: 52 VDPKYVPV 59
>gi|82734223 beta-defensin 124 [Homo sapiens]
Length = 71
Score = 48.5 bits (114), Expect = 1e-06
Identities = 25/62 (40%), Positives = 33/62 (53%), Gaps = 8/62 (12%)
Query: 6 VLLALVVLNLLFYVPPGRSGPNVYIQKIFASCWRLQGTCRPKCLKNEQYRILCDTIHLCC 65
+LL LV L +L +VP GRS F CW+ QG C+ C + E Y LC LCC
Sbjct: 4 LLLFLVALLVLGHVPSGRSE--------FKRCWKGQGACQTYCTRQETYMHLCPDASLCC 55
Query: 66 VN 67
++
Sbjct: 56 LS 57
>gi|16905373 beta-defensin 118 [Homo sapiens]
Length = 123
Score = 38.9 bits (89), Expect = 0.001
Identities = 21/61 (34%), Positives = 27/61 (44%), Gaps = 8/61 (13%)
Query: 6 VLLALVVLNLLFYVPPGRSGPNVYIQKIFASCWRLQGTCRPKCLKNEQYRILCDTIHLCC 65
+LLAL +L LL V P SG CW G CR +C E + C + CC
Sbjct: 4 LLLALPMLVLLPQVIPAYSGEK--------KCWNRSGHCRKQCKDGEAVKDTCKNLRACC 55
Query: 66 V 66
+
Sbjct: 56 I 56
>gi|76563936 defensin, beta 125 preproprotein [Homo sapiens]
Length = 156
Score = 35.8 bits (81), Expect = 0.008
Identities = 19/63 (30%), Positives = 29/63 (46%), Gaps = 9/63 (14%)
Query: 6 VLLALVVLNLLFYVPPGRSGPNVYIQKIFASCWRLQ-GTCRPKCLKNEQYRILCDTIHLC 64
++L ++ LL V G P CW+ G CR +CL E+Y +LC C
Sbjct: 4 LMLTFIICGLLTRVTKGSFEPQ--------KCWKNNVGHCRRRCLDTERYILLCRNKLSC 55
Query: 65 CVN 67
C++
Sbjct: 56 CIS 58
>gi|22748611 defensin, beta 106A precursor [Homo sapiens]
Length = 65
Score = 35.4 bits (80), Expect = 0.010
Identities = 18/56 (32%), Positives = 29/56 (51%), Gaps = 6/56 (10%)
Query: 10 LVVLNLLFYVPPGRSGPNVYIQKIFASCWRLQGTCRPKCLKNEQYRILCDTIHLCC 65
L + +LF++ P + N + + C +L+GTC+ C KNE+ LC CC
Sbjct: 5 LFLFAVLFFLTPAK---NAFFDE---KCNKLKGTCKNNCGKNEELIALCQKSLKCC 54
>gi|103485143 defensin, beta 106B precursor [Homo sapiens]
Length = 65
Score = 35.4 bits (80), Expect = 0.010
Identities = 18/56 (32%), Positives = 29/56 (51%), Gaps = 6/56 (10%)
Query: 10 LVVLNLLFYVPPGRSGPNVYIQKIFASCWRLQGTCRPKCLKNEQYRILCDTIHLCC 65
L + +LF++ P + N + + C +L+GTC+ C KNE+ LC CC
Sbjct: 5 LFLFAVLFFLTPAK---NAFFDE---KCNKLKGTCKNNCGKNEELIALCQKSLKCC 54
>gi|21040279 defensin, beta 127 preproprotein [Homo sapiens]
Length = 99
Score = 35.0 bits (79), Expect = 0.013
Identities = 21/66 (31%), Positives = 29/66 (43%), Gaps = 10/66 (15%)
Query: 8 LALVVLNLLFYVPPGRSGPNVYIQKIFASCWR--LQGTCRPKCLKNEQYRILCDTIHLCC 65
L +++ LLF P + + CW +QG CR C NE LC+ CC
Sbjct: 3 LFMIIAILLFQKPT--------VTEQLKKCWNNYVQGHCRKICRVNEVPEALCENGRYCC 54
Query: 66 VNPKYL 71
+N K L
Sbjct: 55 LNIKEL 60
>gi|83582798 beta-defensin 115 [Homo sapiens]
Length = 88
Score = 33.9 bits (76), Expect = 0.029
Identities = 18/59 (30%), Positives = 31/59 (52%), Gaps = 4/59 (6%)
Query: 8 LALVVLNLLFYVPPGRSGPNVYIQKIFASCWRLQGTCRPKCLKNEQYRILCDTIHLCCV 66
+ L VL L+ V ++ P+ +I++ C+ G CR C + E+ + C H+CCV
Sbjct: 13 IKLSVLALVVLVVLAQTAPDGWIRR----CYYGTGRCRKSCKEIERKKEKCGEKHICCV 67
>gi|239757478 PREDICTED: defensin, beta 117 [Homo sapiens]
Length = 53
Score = 33.5 bits (75), Expect = 0.038
Identities = 12/31 (38%), Positives = 16/31 (51%)
Query: 36 SCWRLQGTCRPKCLKNEQYRILCDTIHLCCV 66
SCW ++G CR C EQ + C CC+
Sbjct: 17 SCWIIKGHCRKNCKPGEQVKKPCKNGDYCCI 47
>gi|239751980 PREDICTED: defensin, beta 117 [Homo sapiens]
Length = 53
Score = 33.5 bits (75), Expect = 0.038
Identities = 12/31 (38%), Positives = 16/31 (51%)
Query: 36 SCWRLQGTCRPKCLKNEQYRILCDTIHLCCV 66
SCW ++G CR C EQ + C CC+
Sbjct: 17 SCWIIKGHCRKNCKPGEQVKKPCKNGDYCCI 47
>gi|239746467 PREDICTED: defensin, beta 117 [Homo sapiens]
Length = 53
Score = 33.5 bits (75), Expect = 0.038
Identities = 12/31 (38%), Positives = 16/31 (51%)
Query: 36 SCWRLQGTCRPKCLKNEQYRILCDTIHLCCV 66
SCW ++G CR C EQ + C CC+
Sbjct: 17 SCWIIKGHCRKNCKPGEQVKKPCKNGDYCCI 47
>gi|83582802 beta-defensin 128 [Homo sapiens]
Length = 93
Score = 32.3 bits (72), Expect = 0.084
Identities = 22/60 (36%), Positives = 30/60 (50%), Gaps = 7/60 (11%)
Query: 8 LALVVLNLLFYVPPGRSGPNVYIQKIFASCWRLQGTCRPKCLKNEQYRILCDTIHLCCVN 67
L LV++ LLF V ++K F ++ G CR KC E+Y I C + LCC N
Sbjct: 3 LFLVLIILLFEVLTD----GARLKKCFN---KVTGYCRKKCKVGERYEIGCLSGKLCCAN 55
>gi|37704382 defensin, beta 119 isoform a precursor [Homo sapiens]
Length = 84
Score = 32.3 bits (72), Expect = 0.084
Identities = 22/71 (30%), Positives = 29/71 (40%), Gaps = 5/71 (7%)
Query: 7 LLALVVLNLLFYVPPGRSGPNVYIQKIFASCWRLQGTCRPKCLKNEQYRILCDTIHLCCV 66
LL L + LL P SG ++ C G CR C KNEQ + C CC+
Sbjct: 3 LLYLFLAILLAIEEPVISGKRHILR-----CMGNSGICRASCKKNEQPYLYCRNCQSCCL 57
Query: 67 NPKYLPILTGK 77
++GK
Sbjct: 58 QSYMRISISGK 68
>gi|23503329 defensin, beta 119 isoform c precursor [Homo sapiens]
Length = 88
Score = 31.2 bits (69), Expect = 0.19
Identities = 16/41 (39%), Positives = 18/41 (43%), Gaps = 1/41 (2%)
Query: 33 IFASCWRLQGTCRPKCLKNEQYRILCDTIHLCCVNPKYLPI 73
I CW + G CR C E I C CCV +YL I
Sbjct: 19 ISVECW-MDGHCRLLCKDGEDSIIRCRNRKRCCVPSRYLTI 58
>gi|46409558 beta-defensin 32 precursor [Homo sapiens]
Length = 95
Score = 30.8 bits (68), Expect = 0.25
Identities = 18/67 (26%), Positives = 27/67 (40%), Gaps = 7/67 (10%)
Query: 6 VLLALVVLNLLFYVPPGRSGPNVYIQKIFASCWRLQGTCRPKCLKNEQYRILCDTIHLCC 65
+LL L L L V P +G + + G CR C E +C+ CC
Sbjct: 4 LLLVLAALGFLTQVIPASAGGSKCVSNT-------PGYCRTCCHWGETALFMCNASRKCC 56
Query: 66 VNPKYLP 72
++ +LP
Sbjct: 57 ISYSFLP 63
>gi|74136827 beta-defensin 134 [Homo sapiens]
Length = 66
Score = 30.0 bits (66), Expect = 0.42
Identities = 19/63 (30%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 10 LVVLNLLFYVPPGRSGPNVYIQKIFASCWRLQGTCRPKCLKNEQYRILCDTIHLCCVNPK 69
LVV LF P +G N ++ C++ G CR +C ++E C CCV
Sbjct: 5 LVVFVFLFLWDPVLAGINSLSSEMHKKCYK-NGICRLECYESEMLVAYCMFQLECCVKGN 63
Query: 70 YLP 72
P
Sbjct: 64 PAP 66
>gi|22748617 defensin, beta 105A precursor [Homo sapiens]
Length = 78
Score = 28.5 bits (62), Expect = 1.2
Identities = 13/30 (43%), Positives = 17/30 (56%)
Query: 36 SCWRLQGTCRPKCLKNEQYRILCDTIHLCC 65
SC +G CR +CL+NE+ C LCC
Sbjct: 45 SCKLGRGKCRKECLENEKPDGNCRLNFLCC 74
>gi|149944551 defensin, beta 131 [Homo sapiens]
Length = 70
Score = 28.5 bits (62), Expect = 1.2
Identities = 20/62 (32%), Positives = 26/62 (41%), Gaps = 6/62 (9%)
Query: 4 RSVLLALVVLNLLFYVPPGRSGPNVYIQKIFASCWRLQGTCRPKCLKNEQYRILCDTIHL 63
R + VL+L+F VPP RS +I C CR KC +E C +
Sbjct: 2 RVLFFVFGVLSLMFTVPPARS----FISN--DECPSEYYHCRLKCNADEHAIRYCADFSI 55
Query: 64 CC 65
CC
Sbjct: 56 CC 57
>gi|103485141 defensin, beta 105B precursor [Homo sapiens]
Length = 78
Score = 28.5 bits (62), Expect = 1.2
Identities = 13/30 (43%), Positives = 17/30 (56%)
Query: 36 SCWRLQGTCRPKCLKNEQYRILCDTIHLCC 65
SC +G CR +CL+NE+ C LCC
Sbjct: 45 SCKLGRGKCRKECLENEKPDGNCRLNFLCC 74
>gi|83582796 beta-defensin 113 [Homo sapiens]
Length = 82
Score = 27.3 bits (59), Expect = 2.7
Identities = 17/67 (25%), Positives = 28/67 (41%), Gaps = 3/67 (4%)
Query: 11 VVLNLLFYVPPGRSGPNVYIQKIFA---SCWRLQGTCRPKCLKNEQYRILCDTIHLCCVN 67
+ L +F V G S P +++ C ++G C+P+C E C+ C V
Sbjct: 6 IFLTFVFTVSCGPSVPQKKTREVAERKRECQLVRGACKPECNSWEYVYYYCNVNPCCAVW 65
Query: 68 PKYLPIL 74
PI+
Sbjct: 66 EYQKPII 72
>gi|24797076 major histocompatibility complex, class II, DP beta 1
precursor [Homo sapiens]
Length = 258
Score = 26.6 bits (57), Expect = 4.6
Identities = 15/44 (34%), Positives = 23/44 (52%)
Query: 2 ATRSVLLALVVLNLLFYVPPGRSGPNVYIQKIFASCWRLQGTCR 45
A R+V L +++ LL V GR+ P Y+ + C+ GT R
Sbjct: 9 APRTVALTALLMVLLTSVVQGRATPENYLFQGRQECYAFNGTQR 52
>gi|239757284 PREDICTED: similar to Fc fragment of IgG binding
protein [Homo sapiens]
Length = 593
Score = 26.6 bits (57), Expect = 4.6
Identities = 10/28 (35%), Positives = 13/28 (46%)
Query: 38 WRLQGTCRPKCLKNEQYRILCDTIHLCC 65
WR + C +C N Y + DT L C
Sbjct: 187 WRTETFCPMECPPNSHYELCADTCSLGC 214
>gi|239753808 PREDICTED: hypothetical protein [Homo sapiens]
Length = 83
Score = 26.6 bits (57), Expect = 4.6
Identities = 18/65 (27%), Positives = 25/65 (38%), Gaps = 7/65 (10%)
Query: 2 ATRSVLLALVVLNLLFYVPPGRSGPNVYIQKIFASCWRLQGTCRPKCLKNEQYRILCDTI 61
A R +L + + V P R K C R G+CR CL+ E + C
Sbjct: 10 AVRIAVLLFAIFFFMSQVLPARG-------KFKEICERPNGSCRDFCLETEIHVGRCLNS 62
Query: 62 HLCCV 66
CC+
Sbjct: 63 RPCCL 67
>gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo
sapiens]
Length = 3003
Score = 26.6 bits (57), Expect = 4.6
Identities = 10/28 (35%), Positives = 13/28 (46%)
Query: 38 WRLQGTCRPKCLKNEQYRILCDTIHLCC 65
WR + C +C N Y + DT L C
Sbjct: 1522 WRTETFCPMECPPNSHYELCADTCSLGC 1549
>gi|239748372 PREDICTED: hypothetical protein [Homo sapiens]
Length = 83
Score = 26.6 bits (57), Expect = 4.6
Identities = 18/65 (27%), Positives = 25/65 (38%), Gaps = 7/65 (10%)
Query: 2 ATRSVLLALVVLNLLFYVPPGRSGPNVYIQKIFASCWRLQGTCRPKCLKNEQYRILCDTI 61
A R +L + + V P R K C R G+CR CL+ E + C
Sbjct: 10 AVRIAVLLFAIFFFMSQVLPARG-------KFKEICERPNGSCRDFCLETEIHVGRCLNS 62
Query: 62 HLCCV 66
CC+
Sbjct: 63 RPCCL 67
>gi|154146262 Fc fragment of IgG binding protein [Homo sapiens]
Length = 5405
Score = 26.6 bits (57), Expect = 4.6
Identities = 10/28 (35%), Positives = 13/28 (46%)
Query: 38 WRLQGTCRPKCLKNEQYRILCDTIHLCC 65
WR + C +C N Y + DT L C
Sbjct: 1522 WRTETFCPMECPPNSHYELCADTCSLGC 1549
Score = 26.6 bits (57), Expect = 4.6
Identities = 10/28 (35%), Positives = 14/28 (50%)
Query: 38 WRLQGTCRPKCLKNEQYRILCDTIHLCC 65
WR + C +C +N Y + DT L C
Sbjct: 2723 WRNETFCPMECPQNSHYELCADTCSLGC 2750
Score = 26.6 bits (57), Expect = 4.6
Identities = 10/28 (35%), Positives = 14/28 (50%)
Query: 38 WRLQGTCRPKCLKNEQYRILCDTIHLCC 65
WR + C +C +N Y + DT L C
Sbjct: 3924 WRNETFCPMECPQNSHYELCADTCSLGC 3951
>gi|134304840 KIAA0319 [Homo sapiens]
Length = 1072
Score = 26.2 bits (56), Expect = 6.0
Identities = 12/26 (46%), Positives = 15/26 (57%)
Query: 2 ATRSVLLALVVLNLLFYVPPGRSGPN 27
AT S AL+V N + Y P +GPN
Sbjct: 511 ATNSTTAALIVNNAVDYPPVANAGPN 536
>gi|83582800 beta-defensin 116 [Homo sapiens]
Length = 102
Score = 26.2 bits (56), Expect = 6.0
Identities = 16/62 (25%), Positives = 26/62 (41%), Gaps = 2/62 (3%)
Query: 7 LLALVVLNLLFYVPPGR--SGPNVYIQKIFASCWRLQGTCRPKCLKNEQYRILCDTIHLC 64
L+ + +L +L PG N ++ + C QG CR C + E + C C
Sbjct: 8 LMTIAILMILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNACREYEIQYLTCPNDQKC 67
Query: 65 CV 66
C+
Sbjct: 68 CL 69
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.330 0.145 0.486
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,341,203
Number of Sequences: 37866
Number of extensions: 126645
Number of successful extensions: 366
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 337
Number of HSP's gapped (non-prelim): 33
length of query: 77
length of database: 18,247,518
effective HSP length: 49
effective length of query: 28
effective length of database: 16,392,084
effective search space: 458978352
effective search space used: 458978352
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.