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Search of human proteins with 116488398
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116488398 keratin 32 [Homo sapiens]
(448 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116488398 keratin 32 [Homo sapiens] 904 0.0
gi|94538345 keratin 35 [Homo sapiens] 565 e-161
gi|4504927 keratin 36 [Homo sapiens] 563 e-160
gi|14917115 keratin 31 [Homo sapiens] 550 e-156
gi|14917117 keratin 33A [Homo sapiens] 528 e-150
gi|10337581 type I hair keratin 3B [Homo sapiens] 527 e-150
gi|14917119 keratin 34 [Homo sapiens] 521 e-148
gi|125490370 type I hair keratin KA36 [Homo sapiens] 473 e-133
gi|148277620 type I hair keratin KA35 [Homo sapiens] 467 e-131
gi|15431318 keratin 38 [Homo sapiens] 463 e-130
gi|55770882 keratin 37 [Homo sapiens] 454 e-127
gi|15431310 keratin 14 [Homo sapiens] 373 e-103
gi|24430190 keratin 15 [Homo sapiens] 370 e-102
gi|4557701 keratin 17 [Homo sapiens] 365 e-101
gi|24234699 keratin 19 [Homo sapiens] 363 e-100
gi|24430192 keratin 16 [Homo sapiens] 360 1e-99
gi|131412225 keratin 13 isoform a [Homo sapiens] 357 2e-98
gi|131412228 keratin 13 isoform b [Homo sapiens] 355 6e-98
gi|195972866 keratin 10 [Homo sapiens] 337 1e-92
gi|4557699 keratin 12 [Homo sapiens] 330 1e-90
gi|27894337 keratin 20 [Homo sapiens] 313 2e-85
gi|153945736 keratin 27 [Homo sapiens] 310 1e-84
gi|114431246 keratin 25D [Homo sapiens] 303 2e-82
gi|192807292 keratin 24 [Homo sapiens] 301 8e-82
gi|31559829 keratin 25 [Homo sapiens] 297 1e-80
gi|40354195 keratin 18 [Homo sapiens] 291 8e-79
gi|4557888 keratin 18 [Homo sapiens] 291 8e-79
gi|55956899 keratin 9 [Homo sapiens] 272 4e-73
gi|31559815 keratin 26 [Homo sapiens] 271 1e-72
gi|27894339 keratin 23 [Homo sapiens] 269 4e-72
>gi|116488398 keratin 32 [Homo sapiens]
Length = 448
Score = 904 bits (2336), Expect = 0.0
Identities = 448/448 (100%), Positives = 448/448 (100%)
Query: 1 MTSSCCVTNNLQASLKSCPRPASVCSSGVNCRPELCLGYVCQPMACLPSVCLPTTFRPAS 60
MTSSCCVTNNLQASLKSCPRPASVCSSGVNCRPELCLGYVCQPMACLPSVCLPTTFRPAS
Sbjct: 1 MTSSCCVTNNLQASLKSCPRPASVCSSGVNCRPELCLGYVCQPMACLPSVCLPTTFRPAS 60
Query: 61 CLSKTYLSSSCQAASGISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQE 120
CLSKTYLSSSCQAASGISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQE
Sbjct: 61 CLSKTYLSSSCQAASGISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQE 120
Query: 121 NAELESRIQEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADD 180
NAELESRIQEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADD
Sbjct: 121 NAELESRIQEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADD 180
Query: 181 FRAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGS 240
FRAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGS
Sbjct: 181 FRAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGS 240
Query: 241 LRCQLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVAT 300
LRCQLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVAT
Sbjct: 241 LRCQLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVAT 300
Query: 301 SSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITN 360
SSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITN
Sbjct: 301 SSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITN 360
Query: 361 VEAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDCKLPCNPCSTPSCTTC 420
VEAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDCKLPCNPCSTPSCTTC
Sbjct: 361 VEAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDCKLPCNPCSTPSCTTC 420
Query: 421 VPSPCVPRTVCVPRTVGMPCSPCPQGRY 448
VPSPCVPRTVCVPRTVGMPCSPCPQGRY
Sbjct: 421 VPSPCVPRTVCVPRTVGMPCSPCPQGRY 448
>gi|94538345 keratin 35 [Homo sapiens]
Length = 455
Score = 565 bits (1456), Expect = e-161
Identities = 309/464 (66%), Positives = 350/464 (75%), Gaps = 25/464 (5%)
Query: 1 MTSSCCVTNNLQASLKSCPRPASVCSSGVNCR--PELCLGYVCQPMACLPSVCLP----T 54
M S C SLKS P AS S+ V+ C P+A S C +
Sbjct: 1 MASKCLKAGFSSGSLKS-PGGASGGSTRVSAMYSSSSCKLPSLSPVARSFSACSVGLGRS 59
Query: 55 TFRPASCLSKTYLSSSCQAASGISGSM-GPGSWYSEGAFNGNEKETMQFLNDRLASYLTR 113
++R SCL + C A G + S G G W+ EG GNEKETMQ LNDRLA YL +
Sbjct: 60 SYRATSCLP-----ALCLPAGGFATSYSGGGGWFGEGILTGNEKETMQSLNDRLAGYLEK 114
Query: 114 VRQLEQENAELESRIQEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDN 173
VRQLEQENA LESRI+E QV M PDYQS+FRTIEELQ+K LC+KAENAR+VV IDN
Sbjct: 115 VRQLEQENASLESRIREWCEQQVPYMCPDYQSYFRTIEELQKKTLCSKAENARLVVEIDN 174
Query: 174 AKLAADDFRAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKN 233
AKLAADDFR KYE E+++RQLVE+DINGLRRILDDLTLCK+DLEAQVESLKEEL+CLKKN
Sbjct: 175 AKLAADDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKKN 234
Query: 234 HEEEVGSLRCQLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEE 293
HEEEV SLRCQLGDRLN+EVDAAPPVDL RVLEEMRCQYE +VE NRRD E+W + Q EE
Sbjct: 235 HEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSEE 294
Query: 294 LNQQVATSSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQ 353
LNQQV +SSEQLQ+ Q++II+LRRTVN LEIELQAQHS+RD+LE+TL E+EARYSSQLAQ
Sbjct: 295 LNQQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLAQ 354
Query: 354 MQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDCKLPCNPCS 413
MQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLE EINTYR LLE+ED KLPCNPC+
Sbjct: 355 MQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESEDSKLPCNPCA 414
Query: 414 -----TPSCTTCVPS----PCVPRTVCVPRTVGMPCSPCPQGRY 448
+ SC C+P+ P RT C PR + C PCP GR+
Sbjct: 415 PDYSPSKSCLPCLPAASCGPSAARTNCSPRPI---CVPCPGGRF 455
>gi|4504927 keratin 36 [Homo sapiens]
Length = 467
Score = 563 bits (1451), Expect = e-160
Identities = 286/386 (74%), Positives = 327/386 (84%), Gaps = 8/386 (2%)
Query: 60 SCLSKTYLSSSCQAASGISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQ 119
SCL +YLSS C SG +G G W+ EG+FNG+EKETMQFLNDRLA+YL +VRQLE+
Sbjct: 61 SCLPGSYLSSECHT----SGFVGSGGWFCEGSFNGSEKETMQFLNDRLANYLEKVRQLER 116
Query: 120 ENAELESRIQEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAAD 179
ENAELESRIQE Q+ + PDYQS+F+TIE+ QQKIL TK+ENAR+V+ IDNAKLAAD
Sbjct: 117 ENAELESRIQEWYEFQIPYICPDYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAAD 176
Query: 180 DFRAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVG 239
DFR KYE EL++RQLVEADINGLRRILD+LTLCKADLEAQVESLKEELMCLKKNHEEEV
Sbjct: 177 DFRTKYETELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVS 236
Query: 240 SLRCQLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVA 299
LRCQLGDRLN+EVDAAPPVDL ++LE+MRCQYEA+VE NRRDVE WFN Q EELNQQV
Sbjct: 237 VLRCQLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVV 296
Query: 300 TSSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMIT 359
+SSEQLQ Q++II+LRRTVN LEIELQAQHS+R+SLE+TL E+EARYSSQLAQMQC+I+
Sbjct: 297 SSSEQLQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLIS 356
Query: 360 NVEAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDCKLPCNPCSTPSCTT 419
NVEAQL+EIR DLERQNQEYQVLLDV+ARLEGEI TYR LLE EDCKLP PC+T +C
Sbjct: 357 NVEAQLSEIRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGEDCKLPPQPCAT-ACKP 415
Query: 420 CVPSPCVPRTVCVPRTVGMPCSPCPQ 445
+ P VP CVP +PC+P PQ
Sbjct: 416 VIRVPSVPPVPCVP---SVPCTPAPQ 438
>gi|14917115 keratin 31 [Homo sapiens]
Length = 416
Score = 550 bits (1416), Expect = e-156
Identities = 278/402 (69%), Positives = 331/402 (82%), Gaps = 2/402 (0%)
Query: 46 CLPSVCLPTTFRPASCLSKTYLSSSCQAASGISGSMGPGSWYSEGAFNGNEKETMQFLND 105
CLPS+ T+ C+ + S + A I ++ +W+ EG+FNG+EKETMQFLND
Sbjct: 6 CLPSLSCRTSCSSRPCVPPSCHSCTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLND 65
Query: 106 RLASYLTRVRQLEQENAELESRIQEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENA 165
RLASYL +VRQLE++NAELE+ I+E S Q + P YQS+F+TIEELQQKILCTK+ENA
Sbjct: 66 RLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCTKSENA 125
Query: 166 RMVVNIDNAKLAADDFRAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKE 225
R+VV IDNAKLAADDFR KY+ EL++RQLVE+DINGLRRILD+LTLCK+DLEAQVESLKE
Sbjct: 126 RLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDELTLCKSDLEAQVESLKE 185
Query: 226 ELMCLKKNHEEEVGSLRCQLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEE 285
EL+CLK NHE+EV +LRCQLGDRLN+EVDAAP VDL RVL E R QYEA+VE NRR+VE+
Sbjct: 186 ELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNETRSQYEALVETNRREVEQ 245
Query: 286 WFNMQMEELNQQVATSSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEA 345
WF Q EELN+QV +SSEQLQ+YQ++II+LRRTVN LEIELQAQH+LRDSLENTLTESEA
Sbjct: 246 WFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEA 305
Query: 346 RYSSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDC 405
RYSSQL+Q+Q +ITNVE+QLAEIR+DLERQNQEYQVLLDVRARLE EINTYRSLLE+EDC
Sbjct: 306 RYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDC 365
Query: 406 KLPCNPCSTPSCTTCVPSPCV--PRTVCVPRTVGMPCSPCPQ 445
LP NPC+T + + PC+ P T CVP PC+P P+
Sbjct: 366 NLPSNPCATTNACSKPIGPCLSNPCTSCVPPAPCTPCAPRPR 407
>gi|14917117 keratin 33A [Homo sapiens]
Length = 404
Score = 528 bits (1361), Expect = e-150
Identities = 271/392 (69%), Positives = 323/392 (82%), Gaps = 10/392 (2%)
Query: 52 LPTTFRPASCLSKTYLSSSCQA-----ASGISGSMGPGSWYSEGAFNGNEKETMQFLNDR 106
LP+ SC S+ + SC A I ++ +W+ EG+FNG+EKETMQFLNDR
Sbjct: 7 LPSLSCRTSCSSRPCVPPSCHGCTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDR 66
Query: 107 LASYLTRVRQLEQENAELESRIQEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENAR 166
LASYL +VRQLE++NAELE+ I+E S Q + YQS+F+TIEELQQKILC+K+ENAR
Sbjct: 67 LASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFKTIEELQQKILCSKSENAR 126
Query: 167 MVVNIDNAKLAADDFRAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEE 226
+VV IDNAKLA+DDFR KYE EL++RQLVE+DINGLRRILD+LTLC++DLEAQVESLKEE
Sbjct: 127 LVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTLCRSDLEAQVESLKEE 186
Query: 227 LMCLKKNHEEEVGSLRCQLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEW 286
L+CLK+NHE+EV +LRCQLGDRLN+EVDAAP VDL +VL E R QYEA+VE NRR+VE+W
Sbjct: 187 LLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNETRSQYEALVETNRREVEQW 246
Query: 287 FNMQMEELNQQVATSSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEAR 346
F Q EELN+QV +SSEQLQ+YQ++II+LRRTVN LEIELQAQH+LRDSLENTLTESEAR
Sbjct: 247 FATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEAR 306
Query: 347 YSSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDCK 406
YSSQL+Q+Q +ITNVE+QLAEIR+DLERQNQEYQVLLDVRARLE EINTYRSLLE+EDCK
Sbjct: 307 YSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCK 366
Query: 407 LPCNPCST-----PSCTTCVPSPCVPRTVCVP 433
LP NPC+T S C+ +PC R C P
Sbjct: 367 LPSNPCATTNACDKSTGPCISNPCGLRARCGP 398
>gi|10337581 type I hair keratin 3B [Homo sapiens]
Length = 404
Score = 527 bits (1358), Expect = e-150
Identities = 269/393 (68%), Positives = 324/393 (82%), Gaps = 10/393 (2%)
Query: 51 CLPTTFRPASCLSKTYLSSSCQA-----ASGISGSMGPGSWYSEGAFNGNEKETMQFLND 105
CLP+ SC S+ + SC A I ++ +W+ EG+FNG+EKETMQFLND
Sbjct: 6 CLPSLSCRTSCSSRPCVPPSCHGYTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLND 65
Query: 106 RLASYLTRVRQLEQENAELESRIQEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENA 165
RLASYL +VRQLE++NAELE+ I+E S Q + P YQS+F+TIEELQQKILC+K+ENA
Sbjct: 66 RLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCSKSENA 125
Query: 166 RMVVNIDNAKLAADDFRAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKE 225
R+VV IDNAKLAADDFR KY+ E ++RQLVE+DIN LRRILD+LTLC++DLEAQ+ESLKE
Sbjct: 126 RLVVQIDNAKLAADDFRTKYQTEQSLRQLVESDINSLRRILDELTLCRSDLEAQMESLKE 185
Query: 226 ELMCLKKNHEEEVGSLRCQLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEE 285
EL+ LK+NHE+EV +LRCQLGDRLN+EVDAAP VDL +VL E R QYEA+VE NRR+VE+
Sbjct: 186 ELLSLKQNHEQEVNTLRCQLGDRLNVEVDAAPAVDLNQVLNETRNQYEALVETNRREVEQ 245
Query: 286 WFNMQMEELNQQVATSSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEA 345
WF Q EELN+QV +SSEQLQ+YQ++II+LRRTVN LEIELQAQH+LR SLENTLTESEA
Sbjct: 246 WFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRYSLENTLTESEA 305
Query: 346 RYSSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDC 405
RYSSQL+Q+Q +ITNVE+QLAEIR+DLERQNQEYQVLLDVRARLE EINTYRSLLE+EDC
Sbjct: 306 RYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDC 365
Query: 406 KLPCNPCSTPSCT-----TCVPSPCVPRTVCVP 433
KLP NPC+T + +CV +PC PR+ C P
Sbjct: 366 KLPSNPCATTNACEKPIGSCVTNPCGPRSRCGP 398
>gi|14917119 keratin 34 [Homo sapiens]
Length = 436
Score = 521 bits (1343), Expect = e-148
Identities = 269/416 (64%), Positives = 324/416 (77%), Gaps = 6/416 (1%)
Query: 15 LKSCPRPASVCSSGVNCRPELCLGYVCQPMACLPSVCLPTTFRPASCLSKTYLSSSCQA- 73
+K R + + ++ + C C S CLP+ SC S+ + SC
Sbjct: 13 IKGLQRKERLKPAHIHLQQLTCFSITCSSTMSY-SCCLPSLGCRTSCSSRPCVPPSCHGY 71
Query: 74 ----ASGISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQENAELESRIQ 129
A I ++ +W+ EG+FNG+EKETMQFLNDRLASYL +VRQLE++NAELE IQ
Sbjct: 72 TLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELEKLIQ 131
Query: 130 EASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDFRAKYEAEL 189
E S Q + P YQS+F+TIEELQQKILC KAENAR+VVNIDNAKLA+DDFR+KY+ E
Sbjct: 132 ERSQQQEPLLCPSYQSYFKTIEELQQKILCAKAENARLVVNIDNAKLASDDFRSKYQTEQ 191
Query: 190 AMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQLGDRL 249
++R LVE+DIN +RRILD+LTLCK+DLE+QVESL+EEL+CLKKNHEEEV +LR QLGDRL
Sbjct: 192 SLRLLVESDINSIRRILDELTLCKSDLESQVESLREELICLKKNHEEEVNTLRSQLGDRL 251
Query: 250 NIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQLQNYQ 309
N+EVD AP VDL +VL E R QYEA+VE NRR+VE+WF Q EELN+QV +SSEQLQ+ Q
Sbjct: 252 NVEVDTAPTVDLNQVLNETRSQYEALVEINRREVEQWFATQTEELNKQVVSSSEQLQSCQ 311
Query: 310 SDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEIR 369
++II+LRRTVN LEIELQAQH+LRDSLENTLTESEA YSSQL+Q+Q +ITNVE+QLAEIR
Sbjct: 312 AEIIELRRTVNALEIELQAQHNLRDSLENTLTESEAHYSSQLSQVQSLITNVESQLAEIR 371
Query: 370 ADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDCKLPCNPCSTPSCTTCVPSPC 425
DLERQNQEYQVLLDVRARLE EINTYRSLLE+EDCKLPCNPC+T + + PC
Sbjct: 372 CDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPCNPCATTNASGNSCGPC 427
>gi|125490370 type I hair keratin KA36 [Homo sapiens]
Length = 431
Score = 473 bits (1217), Expect = e-133
Identities = 250/436 (57%), Positives = 312/436 (71%), Gaps = 17/436 (3%)
Query: 1 MTSSCCVTNNLQASLKSCPRPASVCSSGVNCRPELCLGYVCQPMACLPSVCLPTTFRPAS 60
MTS C T+ S +SC AS C+ +C E C P C S C +F S
Sbjct: 1 MTSDCSSTH---CSPESCGT-ASGCAPASSCSVETA----CLPGTCATSRCQTPSFLSRS 52
Query: 61 -----CLSKTYLSSSCQAASGISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVR 115
CL Y + SC + + G +W +G F NEKETMQFLNDRLASYL +VR
Sbjct: 53 RGLTGCLLPCYFTGSCNSPCLV----GNCAWCEDGVFTSNEKETMQFLNDRLASYLEKVR 108
Query: 116 QLEQENAELESRIQEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAK 175
LE+ NAELESRIQE + + PDYQ +F TIE+LQQKILCTKAEN+R+ V +DN K
Sbjct: 109 SLEETNAELESRIQEQCEQDIPMVCPDYQRYFNTIEDLQQKILCTKAENSRLAVQLDNCK 168
Query: 176 LAADDFRAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHE 235
LA DDF++KYE+EL++RQL+EADI+ L IL++LTLCK+DLEA VESLKE+L+CLKKNHE
Sbjct: 169 LATDDFKSKYESELSLRQLLEADISSLHGILEELTLCKSDLEAHVESLKEDLLCLKKNHE 228
Query: 236 EEVGSLRCQLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELN 295
EEV LR QLGDRL++E+D AP +DL RVL+EMRCQ E ++ NRR+ EEW +Q EELN
Sbjct: 229 EEVNLLREQLGDRLSVELDTAPTLDLNRVLDEMRCQCETVLANNRREAEEWLAVQTEELN 288
Query: 296 QQVATSSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQ 355
QQ +S+EQLQ Q +I++L+RT + LEIELQAQ SL +SLE T+ E+EA+YSSQLAQ+Q
Sbjct: 289 QQQLSSAEQLQGCQMEILELKRTASALEIELQAQQSLTESLECTVAETEAQYSSQLAQIQ 348
Query: 356 CMITNVEAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDCKLPCNPCSTP 415
C+I N+E QLAEIR DLERQNQEYQVLLDV+ARLEGEINTY LL++ED +L C+PCST
Sbjct: 349 CLIDNLENQLAEIRCDLERQNQEYQVLLDVKARLEGEINTYWGLLDSEDSRLSCSPCSTT 408
Query: 416 SCTTCVPSPCVPRTVC 431
++ PC +C
Sbjct: 409 CTSSNTCEPCSAYVIC 424
>gi|148277620 type I hair keratin KA35 [Homo sapiens]
Length = 491
Score = 467 bits (1201), Expect = e-131
Identities = 252/430 (58%), Positives = 312/430 (72%), Gaps = 19/430 (4%)
Query: 2 TSSCCVTNNLQASLKSCPRPASVC--SSGVNCRPELCLGYVCQPMACLPSV-----CLPT 54
T C TN+ ++C R +V SS C P CQP + + C PT
Sbjct: 3 TKGCTTTNSPSTPCQNCSRITNVSTISSNNGCHPGGLTVNNCQPAGHVLRIPWDQGCQPT 62
Query: 55 TFRPASCLSKTYLSSSCQAASGISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRV 114
P C YL ++ A S+ SWY EG N NEKETMQ LN+RLA+YL +V
Sbjct: 63 ---PRFCRKPIYLMNNFNARF----SLDDCSWYGEG-INSNEKETMQILNERLANYLQKV 114
Query: 115 RQLEQENAELESRIQEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNA 174
R LE+ENAELES+IQE S+ ++ + PDY S++ TIEELQQKILCTKAEN+R+V IDN
Sbjct: 115 RMLERENAELESKIQEESNKELPVLCPDYLSYYTTIEELQQKILCTKAENSRLVSQIDNT 174
Query: 175 KLAADDFRAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNH 234
KL ADD RAKYEAE+++RQLVE+D NGL++IL+ LTL KADLEAQV+SLKEEL+CLK NH
Sbjct: 175 KLTADDLRAKYEAEVSLRQLVESDANGLKQILNVLTLGKADLEAQVQSLKEELLCLKNNH 234
Query: 235 EEEVGSLRCQLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEEL 294
+EE+ SL+CQLG+RL+IEV AAP DL +VL+EMRCQYE ++E NR+DVE+WFN Q+EEL
Sbjct: 235 KEEINSLQCQLGERLDIEVTAAPSADLNQVLQEMRCQYEPIMETNRKDVEQWFNTQIEEL 294
Query: 295 NQQVATSSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQM 354
NQQV TSS+Q Q Q +II+LRR+VNTLE+ELQAQH +RDS E LTE+EARY++ L Q+
Sbjct: 295 NQQVVTSSQQQQCCQKEIIELRRSVNTLEVELQAQHRMRDSQECILTETEARYTALLTQI 354
Query: 355 QCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDCKLPCNPCST 414
Q +I N+EAQLAEIR LERQNQEY++LLDV++RLE EI TYRSLLE+ D K PC
Sbjct: 355 QSLIDNLEAQLAEIRCALERQNQEYEILLDVKSRLECEITTYRSLLESSDGKRPC----Y 410
Query: 415 PSCTTCVPSP 424
P T C PSP
Sbjct: 411 PRATKCEPSP 420
>gi|15431318 keratin 38 [Homo sapiens]
Length = 456
Score = 463 bits (1191), Expect = e-130
Identities = 246/401 (61%), Positives = 299/401 (74%), Gaps = 14/401 (3%)
Query: 48 PSVCLPTTFRPASCLSKTYLSSSCQAASGISGSMGPGSWYSEGAFNGNEKETMQFLNDRL 107
PS+CLP T C + L +C I G++G Y E NG+EKETMQFLNDRL
Sbjct: 65 PSLCLPPT-----CHTACPLPGTCH----IPGNIGICGAYGENTLNGHEKETMQFLNDRL 115
Query: 108 ASYLTRVRQLEQENAELESRIQEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARM 167
A+YL +VRQLEQENAELE+ + E S T+ PDYQS+F TIEELQQKILC+KAENAR+
Sbjct: 116 ANYLEKVRQLEQENAELEATLLERSKCHESTVCPDYQSYFHTIEELQQKILCSKAENARL 175
Query: 168 VVNIDNAKLAADDFRAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEEL 227
+V IDNAKLAADDFR K E+E ++RQLVEAD G +++LDD TL KADLEAQ ESLKEE
Sbjct: 176 IVQIDNAKLAADDFRIKLESERSLRQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQ 235
Query: 228 MCLKKNHEEEVGSLRCQLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWF 287
+ LK NHE+EV LR QLG++L IE+D P +DL RVL EMR QYEAM+E NR+DVE+WF
Sbjct: 236 LSLKSNHEQEVKILRSQLGEKLRIELDIEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWF 295
Query: 288 NMQMEELNQQVATSSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARY 347
Q E ++ Q + SE+LQ QS+I++LR TVN LE+E QAQH+L+D L+N+L E+E R+
Sbjct: 296 QAQSEGISLQDMSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRF 355
Query: 348 SSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDCKL 407
++LAQMQ +I+NVE QL+EIRADLERQNQEYQVLLDV+ RLE EI TYR+LLE+EDCKL
Sbjct: 356 GTELAQMQSLISNVEEQLSEIRADLERQNQEYQVLLDVKTRLENEIATYRNLLESEDCKL 415
Query: 408 PCNPCST-PSCTTCVPSPCVPRTVCVP-RTVGMPCSPCPQG 446
PCNPCST PSC T +PC PR C P T G C G
Sbjct: 416 PCNPCSTSPSCVT---APCAPRPSCGPCTTCGPTCGASTTG 453
>gi|55770882 keratin 37 [Homo sapiens]
Length = 449
Score = 454 bits (1167), Expect = e-127
Identities = 243/393 (61%), Positives = 295/393 (75%), Gaps = 18/393 (4%)
Query: 48 PSVCLPTTFRPASCLSKTYLSSSCQAASGISGSMGPGSWYSEGAFNGNEKETMQFLNDRL 107
PS+CLP T A L T C I G++G Y + NG+EKETM+FLNDRL
Sbjct: 65 PSLCLPPTSHTACPLPGT-----CH----IPGNIGICGAYGKNTLNGHEKETMKFLNDRL 115
Query: 108 ASYLTRVRQLEQENAELESRIQEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARM 167
A+YL +VRQLEQENAELE+ + E S T+ PDYQS+FRTIEELQQKILC+KAENAR+
Sbjct: 116 ANYLEKVRQLEQENAELETTLLERSKCHESTVCPDYQSYFRTIEELQQKILCSKAENARL 175
Query: 168 VVNIDNAKLAADDFRAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEEL 227
+V IDNAKLAADDFR K E+E ++ QLVEAD G +++LDD TL KADLEAQ ESLKEE
Sbjct: 176 IVQIDNAKLAADDFRIKLESERSLHQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQ 235
Query: 228 MCLKKNHEEEVGSLRCQLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWF 287
+ LK NHE+EV LR QLG++ IE+D P +DL RVL EMR QYEAMVE N +DVE+WF
Sbjct: 236 LSLKSNHEQEVKILRSQLGEKFRIELDIEPTIDLNRVLGEMRAQYEAMVETNHQDVEQWF 295
Query: 288 NMQMEELNQQVATSSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARY 347
Q E ++ Q + SE+LQ QS+I++LR TVN LE+E QAQH+L+D L+N+L E+E RY
Sbjct: 296 QAQSEGISLQAMSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRY 355
Query: 348 SSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDCKL 407
++LAQMQ +I+N+E QL+EIRADLERQNQEYQVLLDV+ARLE EI TYR+LLE+EDCKL
Sbjct: 356 GTELAQMQSLISNLEEQLSEIRADLERQNQEYQVLLDVKARLENEIATYRNLLESEDCKL 415
Query: 408 PCNPCSTP-SCTTCVPSPCVPRTVCVPRTVGMP 439
PCNPCSTP SCT+C PS C P T G P
Sbjct: 416 PCNPCSTPASCTSC-PS-------CGPVTGGSP 440
>gi|15431310 keratin 14 [Homo sapiens]
Length = 472
Score = 373 bits (958), Expect = e-103
Identities = 195/342 (57%), Positives = 256/342 (74%)
Query: 75 SGISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQENAELESRIQEASHS 134
+G+ G G G +G G+EK TMQ LNDRLASYL +VR LE+ NA+LE +I++
Sbjct: 94 AGLGGGFGGGFAGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQR 153
Query: 135 QVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDFRAKYEAELAMRQL 194
Q DY +F+TIE+L+ KIL +NA +++ IDNA+LAADDFR KYE EL +R
Sbjct: 154 QRPAEIKDYSPYFKTIEDLRNKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMS 213
Query: 195 VEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQLGDRLNIEVD 254
VEADINGLRR+LD+LTL +ADLE Q+ESLKEEL LKKNHEEE+ +LR Q+G +N+E+D
Sbjct: 214 VEADINGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMD 273
Query: 255 AAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQLQNYQSDIID 314
AAP VDL+R+L EMR QYE M E NR+D EEWF + EELN++VAT+SE +Q+ +S+I +
Sbjct: 274 AAPGVDLSRILNEMRDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISE 333
Query: 315 LRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEIRADLER 374
LRRT+ LEIELQ+Q S++ SLEN+L E++ RY QLAQ+Q MI +VE QLA++R ++E+
Sbjct: 334 LRRTMQNLEIELQSQLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQ 393
Query: 375 QNQEYQVLLDVRARLEGEINTYRSLLENEDCKLPCNPCSTPS 416
QNQEY++LLDV+ RLE EI TYR LLE ED L + S+ S
Sbjct: 394 QNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLSSSQFSSGS 435
>gi|24430190 keratin 15 [Homo sapiens]
Length = 456
Score = 370 bits (949), Expect = e-102
Identities = 192/334 (57%), Positives = 251/334 (75%), Gaps = 2/334 (0%)
Query: 76 GISGSMGPGSWYSEGAF-NGNEKETMQFLNDRLASYLTRVRQLEQENAELESRIQEASHS 134
G+ G G G +G +GNEK TMQ LNDRLASYL +VR LE+ NA+LE +I +
Sbjct: 84 GVGGGFGGGFGGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQK 143
Query: 135 QVLTMTP-DYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDFRAKYEAELAMRQ 193
Q T DY +F+TIEEL+ KI+ T +N+R+++ IDNA+LAADDFR KYE ELA+RQ
Sbjct: 144 QTPTSPECDYSQYFKTIEELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQ 203
Query: 194 LVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQLGDRLNIEV 253
VEADINGLRR+LD+LTL + DLE Q+E L EEL LKKNHEEE+ QL ++N+E+
Sbjct: 204 GVEADINGLRRVLDELTLARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEM 263
Query: 254 DAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQLQNYQSDII 313
DAAP VDLTRVL EMR QYEAM E NRRDVE WF + EELN++VA+++E +Q +++I
Sbjct: 264 DAAPGVDLTRVLAEMREQYEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEIT 323
Query: 314 DLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEIRADLE 373
DLRRT+ LEIELQ+Q S++ LEN+L E+E RY++QL Q+Q +I +EAQL+E+R ++E
Sbjct: 324 DLRRTMQELEIELQSQLSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEME 383
Query: 374 RQNQEYQVLLDVRARLEGEINTYRSLLENEDCKL 407
QNQEY++LLD++ RLE EI TYRSLLE +D K+
Sbjct: 384 AQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKM 417
>gi|4557701 keratin 17 [Homo sapiens]
Length = 432
Score = 365 bits (936), Expect = e-101
Identities = 192/339 (56%), Positives = 249/339 (73%), Gaps = 1/339 (0%)
Query: 69 SSCQAASGISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQENAELESRI 128
SSC + G G G +G G EK TMQ LNDRLASYL +VR LE+ N ELE +I
Sbjct: 58 SSCYSF-GSGGGYGSSFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKI 116
Query: 129 QEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDFRAKYEAE 188
++ Q DY ++RTIEELQ KIL +NA +++ IDNA+LAADDFR K+E E
Sbjct: 117 RDWYQRQAPGPARDYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETE 176
Query: 189 LAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQLGDR 248
A+R VEADINGLRR+LD+LTL +ADLE Q+E+LKEEL LKKNHEEE+ +LR Q+G
Sbjct: 177 QALRLSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGE 236
Query: 249 LNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQLQNY 308
+N+E+DAAP VDL+R+L EMR QYE M E NR+D E+WF + EELN++VAT+SE +Q+
Sbjct: 237 INVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSG 296
Query: 309 QSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEI 368
+S+I +LRRT+ LEIELQ+Q S++ SLE L E+E RY QL+Q+Q +I +VE QLA++
Sbjct: 297 KSEISELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQL 356
Query: 369 RADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDCKL 407
R ++E+QNQEY++LLDV+ RLE EI TYR LLE ED L
Sbjct: 357 RCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHL 395
>gi|24234699 keratin 19 [Homo sapiens]
Length = 400
Score = 363 bits (933), Expect = e-100
Identities = 192/357 (53%), Positives = 257/357 (71%), Gaps = 2/357 (0%)
Query: 48 PSVCLPTTFRPASCLSKTYLSSSCQAASGISGSMGPGSWYSEGAFNGNEKETMQFLNDRL 107
PS+ + R S S ++SSS A G G G S+G GNEK TMQ LNDRL
Sbjct: 34 PSIHGGSGGRGVSVSSARFVSSSSSGAYG--GGYGGVLTASDGLLAGNEKLTMQNLNDRL 91
Query: 108 ASYLTRVRQLEQENAELESRIQEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARM 167
ASYL +VR LE N ELE +I++ Q + DY ++ TI++L+ KIL EN+R+
Sbjct: 92 ASYLDKVRALEAANGELEVKIRDWYQKQGPGPSRDYSHYYTTIQDLRDKILGATIENSRI 151
Query: 168 VVNIDNAKLAADDFRAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEEL 227
V+ IDNA+LAADDFR K+E E A+R VEADINGLRR+LD+LTL + DLE Q+E LKEEL
Sbjct: 152 VLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEEL 211
Query: 228 MCLKKNHEEEVGSLRCQLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWF 287
LKKNHEEE+ +LR Q+G ++++EVD+AP DL ++L +MR QYE M E NR+D E WF
Sbjct: 212 AYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQNRKDAEAWF 271
Query: 288 NMQMEELNQQVATSSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARY 347
+ EELN++VA +EQLQ +S++ DLRRT+ LEIELQ+Q S++ +LE+TL E+EAR+
Sbjct: 272 TSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQSQLSMKAALEDTLAETEARF 331
Query: 348 SSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENED 404
+QLA +Q +I+ +EAQL ++RAD ERQNQEYQ L+D+++RLE EI TYRSLLE ++
Sbjct: 332 GAQLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSRLEQEIATYRSLLEGQE 388
>gi|24430192 keratin 16 [Homo sapiens]
Length = 473
Score = 360 bits (925), Expect = 1e-99
Identities = 187/341 (54%), Positives = 250/341 (73%)
Query: 76 GISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQENAELESRIQEASHSQ 135
G+ G G +G G+EK TMQ LNDRLASYL +VR LE+ NA+LE +I++ Q
Sbjct: 97 GLGAGFGGGFAGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQ 156
Query: 136 VLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDFRAKYEAELAMRQLV 195
+ DY +F+TIE+L+ KI+ ENA+ ++ IDNA+LAADDFR KYE ELA+RQ V
Sbjct: 157 RPSEIKDYSPYFKTIEDLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHELALRQTV 216
Query: 196 EADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQLGDRLNIEVDA 255
EAD+NGLRR+LD+LTL + DLE Q+E LKEEL L+KNHEEE+ +LR Q G +N+E+DA
Sbjct: 217 EADVNGLRRVLDELTLARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDA 276
Query: 256 APPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQLQNYQSDIIDL 315
AP VDL+R+L EMR QYE M E NRRD E WF + EELN++VA++SE +Q+ +S++ +L
Sbjct: 277 APGVDLSRILNEMRDQYEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTEL 336
Query: 316 RRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEIRADLERQ 375
RR + LEIELQ+Q S++ SLEN+L E++ RY QL+Q+Q +I +VE QLA++R ++E+Q
Sbjct: 337 RRVLQGLEIELQSQLSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQ 396
Query: 376 NQEYQVLLDVRARLEGEINTYRSLLENEDCKLPCNPCSTPS 416
+QEYQ+LLDV+ RLE EI TYR LLE ED L S S
Sbjct: 397 SQEYQILLDVKTRLEQEIATYRRLLEGEDAHLSSQQASGQS 437
>gi|131412225 keratin 13 isoform a [Homo sapiens]
Length = 458
Score = 357 bits (915), Expect = 2e-98
Identities = 186/329 (56%), Positives = 249/329 (75%), Gaps = 3/329 (0%)
Query: 90 GAFNGNEKETMQFLNDRLASYLTRVRQLEQENAELESRIQEASHSQVLTMTP--DYQSHF 147
G GNEK TMQ LNDRLASYL +VR LE+ NA+LE +I++ H + +P DY ++
Sbjct: 98 GLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDW-HLKQSPASPERDYSPYY 156
Query: 148 RTIEELQQKILCTKAENARMVVNIDNAKLAADDFRAKYEAELAMRQLVEADINGLRRILD 207
+TIEEL+ KIL EN R+++ IDNA+LAADDFR KYE ELA+RQ VEADINGLRR+LD
Sbjct: 157 KTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLD 216
Query: 208 DLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQLGDRLNIEVDAAPPVDLTRVLEE 267
+LTL K DLE Q+ESL EEL +KKNHEEE+ Q+ ++N+E+DA P +DLTRVL E
Sbjct: 217 ELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAE 276
Query: 268 MRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQLQNYQSDIIDLRRTVNTLEIELQ 327
MR QYEAM E NRRD EEWF+ + ELN++V+T++ +Q +++I +LRRT+ LEIELQ
Sbjct: 277 MREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQ 336
Query: 328 AQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRA 387
+Q S++ LENT+ E+E RY+ QL Q+Q +I+++EAQL+E+R+++E QNQEY++LLD++
Sbjct: 337 SQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKT 396
Query: 388 RLEGEINTYRSLLENEDCKLPCNPCSTPS 416
RLE EI TYRSLLE +D K+ P S S
Sbjct: 397 RLEQEIATYRSLLEGQDAKMIGFPSSAGS 425
>gi|131412228 keratin 13 isoform b [Homo sapiens]
Length = 420
Score = 355 bits (910), Expect = 6e-98
Identities = 183/319 (57%), Positives = 245/319 (76%), Gaps = 3/319 (0%)
Query: 90 GAFNGNEKETMQFLNDRLASYLTRVRQLEQENAELESRIQEASHSQVLTMTP--DYQSHF 147
G GNEK TMQ LNDRLASYL +VR LE+ NA+LE +I++ H + +P DY ++
Sbjct: 98 GLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDW-HLKQSPASPERDYSPYY 156
Query: 148 RTIEELQQKILCTKAENARMVVNIDNAKLAADDFRAKYEAELAMRQLVEADINGLRRILD 207
+TIEEL+ KIL EN R+++ IDNA+LAADDFR KYE ELA+RQ VEADINGLRR+LD
Sbjct: 157 KTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLD 216
Query: 208 DLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQLGDRLNIEVDAAPPVDLTRVLEE 267
+LTL K DLE Q+ESL EEL +KKNHEEE+ Q+ ++N+E+DA P +DLTRVL E
Sbjct: 217 ELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAE 276
Query: 268 MRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQLQNYQSDIIDLRRTVNTLEIELQ 327
MR QYEAM E NRRD EEWF+ + ELN++V+T++ +Q +++I +LRRT+ LEIELQ
Sbjct: 277 MREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQ 336
Query: 328 AQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRA 387
+Q S++ LENT+ E+E RY+ QL Q+Q +I+++EAQL+E+R+++E QNQEY++LLD++
Sbjct: 337 SQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKT 396
Query: 388 RLEGEINTYRSLLENEDCK 406
RLE EI TYRSLLE +D K
Sbjct: 397 RLEQEIATYRSLLEGQDAK 415
>gi|195972866 keratin 10 [Homo sapiens]
Length = 584
Score = 337 bits (865), Expect = 1e-92
Identities = 180/331 (54%), Positives = 234/331 (70%), Gaps = 3/331 (0%)
Query: 76 GISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQENAELESRIQE--ASH 133
G G G G G +GNEK TMQ LNDRLASYL +VR LE+ N ELE +I+E H
Sbjct: 126 GFGGGFGGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKH 185
Query: 134 SQVLTMTP-DYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDFRAKYEAELAMR 192
P DY +++TI++L+ +IL +NA +++ IDNA+LAADDFR KYE E+A+R
Sbjct: 186 GNSHQGEPRDYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALR 245
Query: 193 QLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQLGDRLNIE 252
Q VEADINGLRR+LD+LTL KADLE Q+ESL EEL LKKNHEEE+ LR +N+E
Sbjct: 246 QSVEADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVE 305
Query: 253 VDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQLQNYQSDI 312
++AAP VDLT++L MR QYE + E NR+D E WFN + +EL ++ + EQ+ +Y+S+I
Sbjct: 306 MNAAPGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEI 365
Query: 313 IDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEIRADL 372
+LRR V LEIELQ+Q +L+ SLE +L E+E RY QL+Q+Q I+ +E QL +IRA+
Sbjct: 366 TELRRNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAET 425
Query: 373 ERQNQEYQVLLDVRARLEGEINTYRSLLENE 403
E QN EYQ LLD++ RLE EI TYRSLLE E
Sbjct: 426 ECQNTEYQQLLDIKIRLENEIQTYRSLLEGE 456
>gi|4557699 keratin 12 [Homo sapiens]
Length = 494
Score = 330 bits (847), Expect = 1e-90
Identities = 173/329 (52%), Positives = 241/329 (73%), Gaps = 4/329 (1%)
Query: 79 GSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQENAELESRIQEASHSQVL- 137
GS+G S G +G+EKETMQ LNDRLASYL +VR LE+ N ELE++I+E ++
Sbjct: 108 GSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTG 167
Query: 138 ---TMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDFRAKYEAELAMRQL 194
DY ++ IE+L+ KI+ NA++++ IDNA+LAA+DFR KYE ELA+RQ
Sbjct: 168 TADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQG 227
Query: 195 VEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQLGDRLNIEVD 254
VEADINGLRR+LD+LTL + DLE Q+ESL EEL +KKNHE+E+ S R +++E+D
Sbjct: 228 VEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMD 287
Query: 255 AAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQLQNYQSDIID 314
AAP VDLTR+L +MR QYE + E NR+D E WF + EL ++++T++EQLQ+ +S++ D
Sbjct: 288 AAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTD 347
Query: 315 LRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEIRADLER 374
LRR LEIELQ+Q +++ SLE++L E+E Y +QL+Q+Q +I+N+EAQL ++RAD ER
Sbjct: 348 LRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAER 407
Query: 375 QNQEYQVLLDVRARLEGEINTYRSLLENE 403
QN ++Q LL+V+ARLE EI TYR LL+ E
Sbjct: 408 QNVDHQRLLNVKARLELEIETYRRLLDGE 436
>gi|27894337 keratin 20 [Homo sapiens]
Length = 424
Score = 313 bits (802), Expect = 2e-85
Identities = 161/315 (51%), Positives = 225/315 (71%)
Query: 92 FNGNEKETMQFLNDRLASYLTRVRQLEQENAELESRIQEASHSQVLTMTPDYQSHFRTIE 151
F GNEK MQ LNDRLASYL +VR LEQ N++LE +I++ + DY +++R IE
Sbjct: 66 FVGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNAPRAGRDYSAYYRQIE 125
Query: 152 ELQQKILCTKAENARMVVNIDNAKLAADDFRAKYEAELAMRQLVEADINGLRRILDDLTL 211
EL+ +I + +NAR V+ IDNAKLAA+DFR KYE E +R VEAD+ GL ++ DDLTL
Sbjct: 126 ELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVEADLQGLNKVFDDLTL 185
Query: 212 CKADLEAQVESLKEELMCLKKNHEEEVGSLRCQLGDRLNIEVDAAPPVDLTRVLEEMRCQ 271
K DLE Q+E L ++L LKK H+EEV L LG+ +N+EVDAAP ++L ++ EMR +
Sbjct: 186 HKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMNEMRQK 245
Query: 272 YEAMVEANRRDVEEWFNMQMEELNQQVATSSEQLQNYQSDIIDLRRTVNTLEIELQAQHS 331
YE M + N ++ +E F Q L QQV ++E+L+ + + +LRRT +LEIELQ+ S
Sbjct: 246 YEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTELRRTSQSLEIELQSHLS 305
Query: 332 LRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLEG 391
+++SLE+TL E++ARYSSQLA +Q +++++EAQL +IR+++ERQN EY +LLD++ RLE
Sbjct: 306 MKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQNNEYHILLDIKTRLEQ 365
Query: 392 EINTYRSLLENEDCK 406
EI TYR LLE ED K
Sbjct: 366 EIATYRRLLEGEDVK 380
>gi|153945736 keratin 27 [Homo sapiens]
Length = 459
Score = 310 bits (795), Expect = 1e-84
Identities = 164/343 (47%), Positives = 228/343 (66%), Gaps = 11/343 (3%)
Query: 73 AASGISGSMGPGS-------WYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQENAELE 125
+A G G +G GS G +GNEK TMQ LNDRLASYL VR LE+ NA+LE
Sbjct: 54 SAGGYGGGLGGGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLE 113
Query: 126 SRI----QEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDF 181
+I ++ + DY +F I+EL+ +I+ NA +V+ DNA+L ADDF
Sbjct: 114 QKIKGWYEKFGPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDF 173
Query: 182 RAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSL 241
R K+E ELA+ Q VEADINGLRR+LD+LTLC+ DLE Q+E+L EEL LKKNHEEE+ +L
Sbjct: 174 RLKFENELALHQSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKAL 233
Query: 242 RCQLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATS 301
+C G +N+E++AAP VDLT +L MR +YEA+ E NRRD E WFN + L QQ++
Sbjct: 234 QCAAGGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDD 293
Query: 302 SEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNV 361
+ + ++++I+++RT+ TLEIELQ+ + + SLE +LTE+E+ Y +QLAQ+Q I +
Sbjct: 294 AGATTSARNELIEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGAL 353
Query: 362 EAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENED 404
E QL ++R + E Q EY+ LLD++ LE EI TY L++ ED
Sbjct: 354 EEQLHQVRTETEGQKLEYEQLLDIKVHLEKEIETYCLLIDGED 396
>gi|114431246 keratin 25D [Homo sapiens]
Length = 464
Score = 303 bits (777), Expect = 2e-82
Identities = 166/345 (48%), Positives = 224/345 (64%), Gaps = 16/345 (4%)
Query: 73 AASGISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQENAELESRI---- 128
A G +GS G G +GNEK TMQ LNDRLASYL VR LE+ NAELE +I
Sbjct: 70 ACIGFAGSEG-------GLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWY 122
Query: 129 QEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDFRAKYEAE 188
++ + DY + TIE+L+ KI+ + NA +++ IDNA+LAADDFR KYE E
Sbjct: 123 EKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENE 182
Query: 189 LAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQLGDR 248
L + Q VEADINGLRR+LD+LTLC+ D E Q ESL EE+ LKKNHEEE+ +L+C G
Sbjct: 183 LTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGN 242
Query: 249 LNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQLQNY 308
+N+E++AAP VDL +L MR +YEA+ E NR+D E WFN + L QQ++ S
Sbjct: 243 VNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFA 302
Query: 309 QSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEI 368
+S + ++RRT+ TLEI+LQ+ + + SLE +LTE+E+ Y +QLAQ+Q I +E QL ++
Sbjct: 303 RSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQV 362
Query: 369 RADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDCKLPCNPCS 413
R + E Q EY+ LLDV+ LE EI TY L++ + N CS
Sbjct: 363 RTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDG-----NSCS 402
>gi|192807292 keratin 24 [Homo sapiens]
Length = 525
Score = 301 bits (771), Expect = 8e-82
Identities = 156/333 (46%), Positives = 230/333 (69%), Gaps = 10/333 (3%)
Query: 76 GISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQENAELESRIQE----- 130
G+ G +G G G F+G EK+TMQ LNDRLA+YL +VR LE+ N +LE++I+E
Sbjct: 125 GMGGGVGDG-----GLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKY 179
Query: 131 ASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDFRAKYEAELA 190
S DY ++ IE+L+ +I+ ENA ++++IDNA+LAADDFR KYE EL
Sbjct: 180 GPGSGDGGSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELC 239
Query: 191 MRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQLGDRLN 250
+RQ VEADINGLR++LDDLT+ ++DLE Q+ES EEL L+KNHEEE+ +++ G +
Sbjct: 240 LRQSVEADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVT 299
Query: 251 IEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQLQNYQS 310
+E++AAP DLT++L +MR QYE + E NRR+ EE FN Q L Q++T + + ++
Sbjct: 300 VEMNAAPGTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKN 359
Query: 311 DIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEIRA 370
+I +L+RT+ LEIELQ+Q +++ SLE TL ++EA Y +QL+++Q I+ +E ++ +I
Sbjct: 360 EITELKRTLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWG 419
Query: 371 DLERQNQEYQVLLDVRARLEGEINTYRSLLENE 403
+ + QN EY+ LLD++ RLE EI TYR LL+ E
Sbjct: 420 ETKCQNAEYKQLLDIKTRLEVEIETYRRLLDGE 452
>gi|31559829 keratin 25 [Homo sapiens]
Length = 450
Score = 297 bits (760), Expect = 1e-80
Identities = 157/343 (45%), Positives = 226/343 (65%), Gaps = 9/343 (2%)
Query: 73 AASGISGSMGPGSWYS---EGAFNGNEKETMQFLNDRLASYLTRVRQLEQENAELESRI- 128
++ G +G P + ++ G +GNEK TMQ LNDRLASYL V LE+ NA+LE +I
Sbjct: 53 SSGGNTGGGNPCAGFTVNERGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIK 112
Query: 129 ---QEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDFRAKY 185
++ + DY +F I++L+ +I+ + NA V+ IDNA+L ADDFR KY
Sbjct: 113 GWYEKFGPGSCRGLDHDYSRYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKY 172
Query: 186 EAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQL 245
E ELA+ Q VEAD+NGLRR+LD++TLC+ DLE Q E+L EE+ LKKNH+EE+ L+C
Sbjct: 173 ENELALHQSVEADVNGLRRVLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAA 232
Query: 246 GDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQL 305
G +N+E++AAP VDLT +L MR +YEA+ E NRRD E WFN + L QQ++
Sbjct: 233 GGNVNVEMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGAT 292
Query: 306 QNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQL 365
+ ++++ +++RT+ TLEIELQ+ + + SLE +LTE+E+ Y +QLAQ+Q I +E QL
Sbjct: 293 TSARNELTEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQL 352
Query: 366 AEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENED--CK 406
++R + E Q EY+ LLD++ LE EI TY L+ +D CK
Sbjct: 353 HQVRTETEGQKLEYEQLLDIKLHLEKEIETYCLLIGGDDGACK 395
>gi|40354195 keratin 18 [Homo sapiens]
Length = 430
Score = 291 bits (745), Expect = 8e-79
Identities = 161/367 (43%), Positives = 238/367 (64%), Gaps = 17/367 (4%)
Query: 57 RPASCLSKTYLSS-------SCQAASGISGSMGPGSWYS--EGAFNG-----NEKETMQF 102
RP S + Y + S ++ G MG G + G G NEKETMQ
Sbjct: 27 RPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGSGGLATGIAGGLAGMGGIQNEKETMQS 86
Query: 103 LNDRLASYLTRVRQLEQENAELESRIQEASHSQVLTMTPDYQSHFRTIEELQQKILCTKA 162
LNDRLASYL RVR LE EN LES+I+E + D+ +F+ IE+L+ +I
Sbjct: 87 LNDRLASYLDRVRSLETENRRLESKIREHLEKKG-PQVRDWSHYFKIIEDLRAQIFANTV 145
Query: 163 ENARMVVNIDNAKLAADDFRAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVES 222
+NAR+V+ IDNA+LAADDFR KYE ELAMRQ VE DI+GLR+++DD + + LE ++E+
Sbjct: 146 DNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRLQLETEIEA 205
Query: 223 LKEELMCLKKNHEEEVGSLRCQLGDR-LNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRR 281
LKEEL+ +KKNHEEEV L+ Q+ L +EVDA DL +++ ++R QY+ + NR
Sbjct: 206 LKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYDELARKNRE 265
Query: 282 DVEEWFNMQMEELNQQVATSSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLT 341
+++++++ Q+EE V T S ++ ++ + +LRRTV +LEI+L + +L+ SLEN+L
Sbjct: 266 ELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLKASLENSLR 325
Query: 342 ESEARYSSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLE 401
E EARY+ Q+ Q+ ++ ++E++LA+ RA+ +RQ QEY+ LL+++ +LE EI TYR LLE
Sbjct: 326 EVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEIATYRRLLE 385
Query: 402 N-EDCKL 407
+ ED L
Sbjct: 386 DGEDFNL 392
>gi|4557888 keratin 18 [Homo sapiens]
Length = 430
Score = 291 bits (745), Expect = 8e-79
Identities = 161/367 (43%), Positives = 238/367 (64%), Gaps = 17/367 (4%)
Query: 57 RPASCLSKTYLSS-------SCQAASGISGSMGPGSWYS--EGAFNG-----NEKETMQF 102
RP S + Y + S ++ G MG G + G G NEKETMQ
Sbjct: 27 RPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGSGGLATGIAGGLAGMGGIQNEKETMQS 86
Query: 103 LNDRLASYLTRVRQLEQENAELESRIQEASHSQVLTMTPDYQSHFRTIEELQQKILCTKA 162
LNDRLASYL RVR LE EN LES+I+E + D+ +F+ IE+L+ +I
Sbjct: 87 LNDRLASYLDRVRSLETENRRLESKIREHLEKKG-PQVRDWSHYFKIIEDLRAQIFANTV 145
Query: 163 ENARMVVNIDNAKLAADDFRAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVES 222
+NAR+V+ IDNA+LAADDFR KYE ELAMRQ VE DI+GLR+++DD + + LE ++E+
Sbjct: 146 DNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRLQLETEIEA 205
Query: 223 LKEELMCLKKNHEEEVGSLRCQLGDR-LNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRR 281
LKEEL+ +KKNHEEEV L+ Q+ L +EVDA DL +++ ++R QY+ + NR
Sbjct: 206 LKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYDELARKNRE 265
Query: 282 DVEEWFNMQMEELNQQVATSSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLT 341
+++++++ Q+EE V T S ++ ++ + +LRRTV +LEI+L + +L+ SLEN+L
Sbjct: 266 ELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLKASLENSLR 325
Query: 342 ESEARYSSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLE 401
E EARY+ Q+ Q+ ++ ++E++LA+ RA+ +RQ QEY+ LL+++ +LE EI TYR LLE
Sbjct: 326 EVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEIATYRRLLE 385
Query: 402 N-EDCKL 407
+ ED L
Sbjct: 386 DGEDFNL 392
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 272 bits (696), Expect = 4e-73
Identities = 140/327 (42%), Positives = 217/327 (66%), Gaps = 4/327 (1%)
Query: 76 GISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQENAELESRIQE-ASHS 134
G G G G G NEK TMQ LN RLASYL +V+ LE+ N +LE++IQ+
Sbjct: 136 GFGGGAGGGDG---GILTANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKK 192
Query: 135 QVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDFRAKYEAELAMRQL 194
+ +Y ++ TI++L+ +I+ N + +++IDN ++ DDFR K+E E +RQ
Sbjct: 193 GPAAIQKNYSPYYNTIDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQG 252
Query: 195 VEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRCQLGDRLNIEVD 254
V+ADINGLR++LD+LT+ K+DLE Q E+L+EELM LKKNH+EE+ L Q +N+E++
Sbjct: 253 VDADINGLRQVLDNLTMEKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEIN 312
Query: 255 AAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSEQLQNYQSDIID 314
AP DLT+ L +MR +YE ++ NR+D+E + Q+ ++ +V++S +++Q+ ++
Sbjct: 313 VAPGKDLTKTLNDMRQEYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQ 372
Query: 315 LRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEAQLAEIRADLER 374
LR V LEIELQ+Q S + +LE +L +++ RY QL +Q I+N+EAQ+ ++R ++E
Sbjct: 373 LRHGVQELEIELQSQLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIEC 432
Query: 375 QNQEYQVLLDVRARLEGEINTYRSLLE 401
QNQEY +LL ++ RLE EI TY +LLE
Sbjct: 433 QNQEYSLLLSIKMRLEKEIETYHNLLE 459
>gi|31559815 keratin 26 [Homo sapiens]
Length = 468
Score = 271 bits (692), Expect = 1e-72
Identities = 152/343 (44%), Positives = 213/343 (62%), Gaps = 5/343 (1%)
Query: 69 SSCQAASGISGSMGPGSWYSEGAF-NGNEKETMQFLNDRLASYLTRVRQLEQENAELESR 127
S C + G+ G +E + +GNEK TMQ LNDRLASYL V LE+ NA+LE +
Sbjct: 55 SFCNSGGGLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQK 114
Query: 128 I----QEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDFRA 183
I ++ DY +F IE+L+++I NA +V+ DNA+L ADDFR
Sbjct: 115 IKGRYEKCEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVLQNDNARLTADDFRL 174
Query: 184 KYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSLRC 243
KYE ELA+ VEAD +GLRR+LD+LTLC DLE Q E+L EEL LKK+HEEE+ L+
Sbjct: 175 KYENELALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQY 234
Query: 244 QLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATSSE 303
G +N+E++A P VDLT +L MR +YE + E NR+D E WFN + L QQ++
Sbjct: 235 TAGGNVNVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEG 294
Query: 304 QLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNVEA 363
++++ +L+R + TLEIELQ+ +++ S E +L E+E Y +QL Q+Q I +E
Sbjct: 295 AATAARNELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEE 354
Query: 364 QLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDCK 406
QL +IR + E Q EY+ LLDV+ LE EI+ Y +LL+ E+ K
Sbjct: 355 QLQQIRTETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEERK 397
>gi|27894339 keratin 23 [Homo sapiens]
Length = 422
Score = 269 bits (687), Expect = 4e-72
Identities = 145/342 (42%), Positives = 218/342 (63%), Gaps = 6/342 (1%)
Query: 62 LSKTYLSSSCQAASGISGSMGPGSWYSEGAFNGNEKETMQFLNDRLASYLTRVRQLEQEN 121
+S ++ + SC G GS S GN K TMQ LNDRLASYL +VR LE+ N
Sbjct: 43 ISLSFTTRSCPPPGG-----SWGSGRSSPLLGGNGKATMQNLNDRLASYLEKVRALEEAN 97
Query: 122 AELESRIQEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARMVVNIDNAKLAADDF 181
+LESRI + + DY + I LQ++I+ K NA++++ IDNA++A DDF
Sbjct: 98 MKLESRILKWHQQRDPGSKKDYSQYEENITHLQEQIVDGKMTNAQIILLIDNARMAVDDF 157
Query: 182 RAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEELMCLKKNHEEEVGSL 241
KYE E + ++ +E ++ GLRR LD+LT+ DLE +VE +++EL+ +KK+HE+E+
Sbjct: 158 NLKYENEHSFKKDLEIEVEGLRRTLDNLTIVTTDLEQEVEGMRKELILMKKHHEQEMEKH 217
Query: 242 RCQLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWFNMQMEELNQQVATS 301
+N++VD P DL +VLE+MR +YE +++ RD++ W+ Q ++Q+ A S
Sbjct: 218 HVPSDFNVNVKVDTGPREDLIKVLEDMRQEYELIIKKKHRDLDTWYKEQSAAMSQE-AAS 276
Query: 302 SEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARYSSQLAQMQCMITNV 361
+Q+ Q DI +L+RT LEI+LQ Q+S + +LEN L+E+++RYS +L MQ +I++
Sbjct: 277 PATVQSRQGDIHELKRTFQALEIDLQTQYSTKSALENMLSETQSRYSCKLQDMQEIISHY 336
Query: 362 EAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENE 403
E +L ++R +LERQN EYQVLL ++ LE EI TYR LLE E
Sbjct: 337 EEELTQLRHELERQNNEYQVLLGIKTHLEKEITTYRRLLEGE 378
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.129 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,855,268
Number of Sequences: 37866
Number of extensions: 788534
Number of successful extensions: 7960
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 285
Number of HSP's successfully gapped in prelim test: 452
Number of HSP's that attempted gapping in prelim test: 4127
Number of HSP's gapped (non-prelim): 2506
length of query: 448
length of database: 18,247,518
effective HSP length: 106
effective length of query: 342
effective length of database: 14,233,722
effective search space: 4867932924
effective search space used: 4867932924
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.