Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 239744142

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239744142 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
         (629 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239744142 PREDICTED: hypothetical protein isoform 1 [Homo sap...  1309   0.0  
gi|239744140 PREDICTED: hypothetical protein [Homo sapiens]          1283   0.0  
gi|169191513 PREDICTED: hypothetical protein isoform 1 [Homo sap...  1277   0.0  
gi|150170710 hypothetical protein LOC728118 [Homo sapiens]           1261   0.0  
gi|57528101 hypothetical protein LOC728130 [Homo sapiens]            1117   0.0  
gi|113865921 hypothetical protein LOC441457 [Homo sapiens]            887   0.0  
gi|148806874 hypothetical protein LOC54754 [Homo sapiens]             887   0.0  
gi|50233787 nuclear protein in testis [Homo sapiens]                  436   e-122
gi|110349719 titin isoform N2-A [Homo sapiens]                         54   3e-07
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    52   2e-06
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     52   2e-06
gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo sap...    51   3e-06
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    50   6e-06
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       49   1e-05
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 49   1e-05
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         48   2e-05
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   47   4e-05
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   47   4e-05
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   47   4e-05
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    47   4e-05
gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo sap...    47   4e-05
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    47   5e-05
gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens]       47   5e-05
gi|226051634 zinc finger protein 414 isoform 1 [Homo sapiens]          47   7e-05
gi|226051591 zinc finger protein 414 isoform 2 [Homo sapiens]          47   7e-05
gi|55750053 atrophin-1 [Homo sapiens]                                  47   7e-05
gi|55750041 atrophin-1 [Homo sapiens]                                  47   7e-05
gi|18959210 WIRE protein [Homo sapiens]                                47   7e-05
gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom...    46   9e-05
gi|210032580 SET domain containing 1B [Homo sapiens]                   46   9e-05

>gi|239744142 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 629

 Score = 1309 bits (3388), Expect = 0.0
 Identities = 629/629 (100%), Positives = 629/629 (100%)

Query: 1   MEVKGPSGRSFCCESEGQFKSCLKRHTPSLLLPSSWKGNSGSCLMAEALHRTSPTPNSCP 60
           MEVKGPSGRSFCCESEGQFKSCLKRHTPSLLLPSSWKGNSGSCLMAEALHRTSPTPNSCP
Sbjct: 1   MEVKGPSGRSFCCESEGQFKSCLKRHTPSLLLPSSWKGNSGSCLMAEALHRTSPTPNSCP 60

Query: 61  LPLPLCRMSGVLCSRNLFTFKFSLFQLDSGASGEPGHSLGLTLGFSYCGNCQTAVVSAQP 120
           LPLPLCRMSGVLCSRNLFTFKFSLFQLDSGASGEPGHSLGLTLGFSYCGNCQTAVVSAQP
Sbjct: 61  LPLPLCRMSGVLCSRNLFTFKFSLFQLDSGASGEPGHSLGLTLGFSYCGNCQTAVVSAQP 120

Query: 121 EGMASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLST 180
           EGMASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLST
Sbjct: 121 EGMASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLST 180

Query: 181 FPSTPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGG 240
           FPSTPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGG
Sbjct: 181 FPSTPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGG 240

Query: 241 VVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGP 300
           VVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGP
Sbjct: 241 VVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGP 300

Query: 301 WPQGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFL 360
           WPQGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFL
Sbjct: 301 WPQGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFL 360

Query: 361 IPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQ 420
           IPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQ
Sbjct: 361 IPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQ 420

Query: 421 WMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARR 480
           WMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARR
Sbjct: 421 WMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARR 480

Query: 481 PPPQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK 540
           PPPQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK
Sbjct: 481 PPPQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK 540

Query: 541 QREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDF 600
           QREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDF
Sbjct: 541 QREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDF 600

Query: 601 LALSQDLEQEEGLTLAQGAPSDAPGTDRC 629
           LALSQDLEQEEGLTLAQGAPSDAPGTDRC
Sbjct: 601 LALSQDLEQEEGLTLAQGAPSDAPGTDRC 629


>gi|239744140 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 878

 Score = 1283 bits (3319), Expect = 0.0
 Identities = 617/617 (100%), Positives = 617/617 (100%)

Query: 1   MEVKGPSGRSFCCESEGQFKSCLKRHTPSLLLPSSWKGNSGSCLMAEALHRTSPTPNSCP 60
           MEVKGPSGRSFCCESEGQFKSCLKRHTPSLLLPSSWKGNSGSCLMAEALHRTSPTPNSCP
Sbjct: 1   MEVKGPSGRSFCCESEGQFKSCLKRHTPSLLLPSSWKGNSGSCLMAEALHRTSPTPNSCP 60

Query: 61  LPLPLCRMSGVLCSRNLFTFKFSLFQLDSGASGEPGHSLGLTLGFSYCGNCQTAVVSAQP 120
           LPLPLCRMSGVLCSRNLFTFKFSLFQLDSGASGEPGHSLGLTLGFSYCGNCQTAVVSAQP
Sbjct: 61  LPLPLCRMSGVLCSRNLFTFKFSLFQLDSGASGEPGHSLGLTLGFSYCGNCQTAVVSAQP 120

Query: 121 EGMASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLST 180
           EGMASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLST
Sbjct: 121 EGMASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLST 180

Query: 181 FPSTPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGG 240
           FPSTPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGG
Sbjct: 181 FPSTPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGG 240

Query: 241 VVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGP 300
           VVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGP
Sbjct: 241 VVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGP 300

Query: 301 WPQGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFL 360
           WPQGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFL
Sbjct: 301 WPQGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFL 360

Query: 361 IPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQ 420
           IPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQ
Sbjct: 361 IPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQ 420

Query: 421 WMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARR 480
           WMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARR
Sbjct: 421 WMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARR 480

Query: 481 PPPQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK 540
           PPPQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK
Sbjct: 481 PPPQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK 540

Query: 541 QREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDF 600
           QREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDF
Sbjct: 541 QREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDF 600

Query: 601 LALSQDLEQEEGLTLAQ 617
           LALSQDLEQEEGLTLAQ
Sbjct: 601 LALSQDLEQEEGLTLAQ 617


>gi|169191513 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 878

 Score = 1277 bits (3305), Expect = 0.0
 Identities = 614/617 (99%), Positives = 615/617 (99%)

Query: 1   MEVKGPSGRSFCCESEGQFKSCLKRHTPSLLLPSSWKGNSGSCLMAEALHRTSPTPNSCP 60
           MEVKGPSGRSFCCESEGQFKSCLKRHTPSLLLPSSWKGNSGSCLMAEALHRTSPTPNSCP
Sbjct: 1   MEVKGPSGRSFCCESEGQFKSCLKRHTPSLLLPSSWKGNSGSCLMAEALHRTSPTPNSCP 60

Query: 61  LPLPLCRMSGVLCSRNLFTFKFSLFQLDSGASGEPGHSLGLTLGFSYCGNCQTAVVSAQP 120
           LPLPLCRMSGVLCSRNLFTFKFSLFQLDSGASGEPGHSLGLTLGFSYCGNCQTAVVSAQP
Sbjct: 61  LPLPLCRMSGVLCSRNLFTFKFSLFQLDSGASGEPGHSLGLTLGFSYCGNCQTAVVSAQP 120

Query: 121 EGMASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLST 180
           EGMASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLST
Sbjct: 121 EGMASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLST 180

Query: 181 FPSTPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGG 240
           FPSTPLVTEQDGC PSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGG
Sbjct: 181 FPSTPLVTEQDGCGPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGG 240

Query: 241 VVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGP 300
           VVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGP
Sbjct: 241 VVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGP 300

Query: 301 WPQGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFL 360
           WPQGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFL
Sbjct: 301 WPQGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFL 360

Query: 361 IPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQ 420
           IPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQ
Sbjct: 361 IPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQ 420

Query: 421 WMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARR 480
           WMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKA TACLPPPRPQRPVTKARR
Sbjct: 421 WMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARR 480

Query: 481 PPPQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK 540
           PPP+PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK
Sbjct: 481 PPPRPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK 540

Query: 541 QREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDF 600
           QREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDF
Sbjct: 541 QREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDF 600

Query: 601 LALSQDLEQEEGLTLAQ 617
           LALSQDLEQEEGLTLAQ
Sbjct: 601 LALSQDLEQEEGLTLAQ 617


>gi|150170710 hypothetical protein LOC728118 [Homo sapiens]
          Length = 878

 Score = 1261 bits (3263), Expect = 0.0
 Identities = 605/617 (98%), Positives = 610/617 (98%)

Query: 1   MEVKGPSGRSFCCESEGQFKSCLKRHTPSLLLPSSWKGNSGSCLMAEALHRTSPTPNSCP 60
           MEVKGPSGRSFCCESEGQFKSCLKRHTPSLLLPSSWKGNSGSCLMA+ALHR SPTPNSCP
Sbjct: 1   MEVKGPSGRSFCCESEGQFKSCLKRHTPSLLLPSSWKGNSGSCLMAKALHRMSPTPNSCP 60

Query: 61  LPLPLCRMSGVLCSRNLFTFKFSLFQLDSGASGEPGHSLGLTLGFSYCGNCQTAVVSAQP 120
           LPLPLCRMSGVLCSRNLFTFKFSLFQLDSGASGEPGHSLGLTLGFS+CGNCQTAVVSAQP
Sbjct: 61  LPLPLCRMSGVLCSRNLFTFKFSLFQLDSGASGEPGHSLGLTLGFSHCGNCQTAVVSAQP 120

Query: 121 EGMASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLST 180
           EGMASNGAYP LGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLST
Sbjct: 121 EGMASNGAYPALGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLST 180

Query: 181 FPSTPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGG 240
            PSTPLVTEQDGC PSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGG
Sbjct: 181 LPSTPLVTEQDGCGPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGG 240

Query: 241 VVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGP 300
           VVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGP
Sbjct: 241 VVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGP 300

Query: 301 WPQGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFL 360
           WPQGAHGE SLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFL
Sbjct: 301 WPQGAHGEGSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFL 360

Query: 361 IPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQ 420
           IPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQ
Sbjct: 361 IPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQ 420

Query: 421 WMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARR 480
           WMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKA TACLPPPRPQRPVTKARR
Sbjct: 421 WMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARR 480

Query: 481 PPPQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK 540
           PPP+PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK
Sbjct: 481 PPPRPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK 540

Query: 541 QREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDF 600
           QREEG+VKQPQEEDWTPPDPGLLSY DKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDF
Sbjct: 541 QREEGEVKQPQEEDWTPPDPGLLSYTDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDF 600

Query: 601 LALSQDLEQEEGLTLAQ 617
           LALSQ+LEQEEGLTLAQ
Sbjct: 601 LALSQELEQEEGLTLAQ 617


>gi|57528101 hypothetical protein LOC728130 [Homo sapiens]
          Length = 557

 Score = 1117 bits (2888), Expect = 0.0
 Identities = 536/550 (97%), Positives = 541/550 (98%)

Query: 80  FKFSLFQLDSGASGEPGHSLGLTLGFSYCGNCQTAVVSAQPEGMASNGAYPVLGPGVTAN 139
           F+  LFQLDSGASGEPGHSLGLTLGFS+CGNCQTAVVSAQPEGMASNGAYP LGPGVTAN
Sbjct: 8   FQIFLFQLDSGASGEPGHSLGLTLGFSHCGNCQTAVVSAQPEGMASNGAYPALGPGVTAN 67

Query: 140 PGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSTFPSTPLVTEQDGCSPSGAG 199
           PGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLS FPSTPLVTEQDGC PSGAG
Sbjct: 68  PGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSNFPSTPLVTEQDGCGPSGAG 127

Query: 200 ASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMA 259
           ASNVFVQMRTEVGPVKAAQAQTLVLTQ PLVWQAPGALCGGVVCPPPLLLAAAPVVPVMA
Sbjct: 128 ASNVFVQMRTEVGPVKAAQAQTLVLTQTPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMA 187

Query: 260 AQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGESSLASSQAKAP 319
           AQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGE SLASSQAKAP
Sbjct: 188 AQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGEGSLASSQAKAP 247

Query: 320 PDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEG 379
           PDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEG
Sbjct: 248 PDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEG 307

Query: 380 LWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPR 439
           LWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPR
Sbjct: 308 LWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPR 367

Query: 440 GPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHRRAETKARLPPPR 499
           GPPAPEVVKQPVYLPSKAGPKA TACLPPPRPQRPVTKARRPPP+PHRRAETKARLPPPR
Sbjct: 368 GPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRRAETKARLPPPR 427

Query: 500 PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKVKQPQEEDWTPPD 559
           PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG+VKQPQEEDWTPPD
Sbjct: 428 PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGEVKQPQEEDWTPPD 487

Query: 560 PGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLALSQDLEQEEGLTLAQGA 619
           PGLLSY DKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLALSQ+LEQEEGLTLAQGA
Sbjct: 488 PGLLSYTDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLALSQELEQEEGLTLAQGA 547

Query: 620 PSDAPGTDRC 629
           PSDAPGTDRC
Sbjct: 548 PSDAPGTDRC 557


>gi|113865921 hypothetical protein LOC441457 [Homo sapiens]
          Length = 492

 Score =  887 bits (2292), Expect = 0.0
 Identities = 439/507 (86%), Positives = 450/507 (88%), Gaps = 15/507 (2%)

Query: 123 MASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSTFP 182
           MASNGAYPVLGPGVT NPGTSLSVFTALPF TP+PGP H P LVTA  PP GPLVLS FP
Sbjct: 1   MASNGAYPVLGPGVTVNPGTSLSVFTALPFATPSPGPTHRPPLVTAVVPPAGPLVLSAFP 60

Query: 183 STPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGGVV 242
           STPLV  QDG  PSGAGASNVFVQMRTEVGPVK  QAQTL+LTQAPLVWQAPG LCGGV+
Sbjct: 61  STPLVAGQDGRGPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVM 120

Query: 243 CPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWP 302
           CPPPLLLAAAP VPV +AQVVGGTQACEGGWS GLPLPPPPP AAQ+ PIVS GNAGPWP
Sbjct: 121 CPPPLLLAAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPPPP-AAQVAPIVSPGNAGPWP 179

Query: 303 QGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP 362
           QGAHGE SLA SQAKA PDDSC P+SVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP
Sbjct: 180 QGAHGEGSLAPSQAKARPDDSCKPKSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP 239

Query: 363 VLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWM 422
           VLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMA KFLEFEAEEEMQIQKSQWM
Sbjct: 240 VLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAAKFLEFEAEEEMQIQKSQWM 299

Query: 423 KGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPP 482
           KGPQ LPPPA PRLEPRGPPAPEVVKQPVYLPSK GPKA TACLPPPRPQRP        
Sbjct: 300 KGPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRP-------- 351

Query: 483 PQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQR 542
                 AETKA LPPPRP RPAETKVPEEIPPEVVQEYVDIMEELLG   G TGEPE QR
Sbjct: 352 ------AETKAHLPPPRPPRPAETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQR 405

Query: 543 EEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLA 602
           E+GKV+QPQEED    DPGLLSYIDKLCSQ+DFVTKVEAVIHP+FLEELLSPDPQMDFLA
Sbjct: 406 EKGKVEQPQEEDGMTSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLSPDPQMDFLA 465

Query: 603 LSQDLEQEEGLTLAQGAPSDAPGTDRC 629
           LSQ+LEQEEGLTLAQGAPSDA GTDRC
Sbjct: 466 LSQELEQEEGLTLAQGAPSDALGTDRC 492


>gi|148806874 hypothetical protein LOC54754 [Homo sapiens]
          Length = 756

 Score =  887 bits (2292), Expect = 0.0
 Identities = 437/496 (88%), Positives = 449/496 (90%), Gaps = 2/496 (0%)

Query: 123 MASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSTFP 182
           MASNGAYPVLGPGVT NPGTSLSVFTALPF TPAPGPAH P LVTA  PP GPLVLS FP
Sbjct: 1   MASNGAYPVLGPGVTVNPGTSLSVFTALPFATPAPGPAHRPPLVTAVVPPAGPLVLSAFP 60

Query: 183 STPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGGVV 242
           STPLV  QDG  PSGAGASNVFVQMRTEVGPVK  QAQTL+LTQAPLVWQAPG LCGGV+
Sbjct: 61  STPLVAGQDGRGPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVM 120

Query: 243 CPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWP 302
           CPPPLLLAAAP VPV +AQVVGGTQACEGGWS GLPLPPPPP AAQ+ PIVS GNA PWP
Sbjct: 121 CPPPLLLAAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPPPP-AAQVAPIVSPGNARPWP 179

Query: 303 QGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP 362
           QGAHGE SLA SQAKA PDDSC P+SVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP
Sbjct: 180 QGAHGEGSLAPSQAKARPDDSCKPKSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIP 239

Query: 363 VLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWM 422
           VLRSLARRKPTMTLEEGLW+AMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWM
Sbjct: 240 VLRSLARRKPTMTLEEGLWQAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWM 299

Query: 423 KGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPV-TKARRP 481
           KGPQ LPPPA PRLEPRGPPAPEVVKQPVYLPSK GPKA TACLPPPRPQRP  TKA  P
Sbjct: 300 KGPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLP 359

Query: 482 PPQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQ 541
           PP+P R AET A LPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLG   G TGEPE Q
Sbjct: 360 PPRPQRPAETNAHLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQ 419

Query: 542 REEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFL 601
           RE+GKV+QPQEED    DPGLLSYIDKLCSQ+DFVTKVEAVIHP+FLEELLSPDPQMDFL
Sbjct: 420 REKGKVEQPQEEDGITSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLSPDPQMDFL 479

Query: 602 ALSQDLEQEEGLTLAQ 617
           ALSQ+LEQEEGLTLAQ
Sbjct: 480 ALSQELEQEEGLTLAQ 495


>gi|50233787 nuclear protein in testis [Homo sapiens]
          Length = 1132

 Score =  436 bits (1122), Expect = e-122
 Identities = 264/504 (52%), Positives = 315/504 (62%), Gaps = 48/504 (9%)

Query: 123 MASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAP-------PGGP 175
           MAS+GA  + GP ++  P  +LS   ALPF  P   P   P       P       P  P
Sbjct: 1   MASDGASALPGPDMSMKPSAALSPSPALPFLPPTSDPPDHPPREPPPQPIMPSVFSPDNP 60

Query: 176 LVLSTFPSTPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPG 235
           L+LS FPS+ LVT   G   SGAGA  V V+++TE G  + +Q Q  +LTQ  L   APG
Sbjct: 61  LMLSAFPSSLLVTGDGGPCLSGAGAGKVIVKVKTEGGSAEPSQTQNFILTQTALNSTAPG 120

Query: 236 ALCGGVVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQ 295
             CGG+  P P  + A+ V  ++ ++ VG +Q  EG    GLP P PPPP AQL PIV  
Sbjct: 121 TPCGGLEGPAPPFVTASNVKTILPSKAVGVSQ--EG--PPGLP-PQPPPPVAQLVPIVPL 175

Query: 296 GNAGPWPQGAHGESSLASSQAKAPPDDSCN-PRSVYENFRLWQHYKPLARRHLPQSPDTE 354
             A P P G  GE    ++ +K    D     + VYENFR WQ YK LARRHL QSPDTE
Sbjct: 176 EKAWPGPHGTTGEGGPVATLSKPSLGDRSKISKDVYENFRQWQRYKALARRHLSQSPDTE 235

Query: 355 ALSCFLIPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEM 414
           ALSCFLIPVLRSLAR KPTMTLEEGL  A++EW+HTSNFDRMIFYEMAE+F+EFEA EEM
Sbjct: 236 ALSCFLIPVLRSLARLKPTMTLEEGLPLAVQEWEHTSNFDRMIFYEMAERFMEFEA-EEM 294

Query: 415 QIQKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRP 474
           QIQ +Q M G Q L P    +L+P GP A EV +QPVY+P KA  K +        P+R 
Sbjct: 295 QIQNTQLMNGSQGLSPATPLKLDPLGPLASEVCQQPVYIPKKAASKTRA-------PRRR 347

Query: 475 VTKARRPPPQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGA 534
             KA+RPP                        + P+EIPPE V+EYVDIME L+G  L A
Sbjct: 348 QRKAQRPP----------------------APEAPKEIPPEAVKEYVDIMEWLVGTHL-A 384

Query: 535 TGEPE-KQREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLS 593
           TGE + KQ EEG   Q QEE+   PDPGLLSYI++LCSQK FV+KVEAVIHPQFL +LLS
Sbjct: 385 TGESDGKQEEEG---QQQEEEGMYPDPGLLSYINELCSQKVFVSKVEAVIHPQFLADLLS 441

Query: 594 PDPQMDFLALSQDLEQEEGLTLAQ 617
           P+ Q D LAL ++LEQEEGLTLAQ
Sbjct: 442 PEKQRDPLALIEELEQEEGLTLAQ 465


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 54/241 (22%), Positives = 96/241 (39%), Gaps = 46/241 (19%)

Query: 342  LARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEM 401
            ++++ +PQ P    +   +I V       K  +  EE ++ A       S+ +  +   +
Sbjct: 9209 VSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFA-------SHTEEEVSVTV 9261

Query: 402  AEKFLEFEAEEEMQIQKSQWMKGP-------------QCLPPPATPRLEPRGPPAPEVVK 448
             E   E   EE++ +  S+ ++ P             +  P P   ++EP  P  PEV K
Sbjct: 9262 PEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPK 9321

Query: 449  QPVYLPSKAGPKAQTACLPPPR----PQRPVTKARRPPPQPHRRAETKARLPPPRPQRPA 504
            +PV    K  P  +     PP+    P++PV + + P P   ++    A++P  +     
Sbjct: 9322 KPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVT 9381

Query: 505  ETKVP-----EEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKVKQPQEEDWTPPD 559
            E K+      EE PP  V E                  P+K+  E +   P++E+  PP 
Sbjct: 9382 EEKITIVTQREESPPPAVPEI-----------------PKKKVPEERKPVPRKEEEVPPP 9424

Query: 560  P 560
            P
Sbjct: 9425 P 9425



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 62/231 (26%), Positives = 96/231 (41%), Gaps = 50/231 (21%)

Query: 377   EEGLWRAMREW----QHTSNFDRMIFYEMAEKFLE-FEAEEEMQIQKSQWM-KGPQC--- 427
             EEG +  + E+    QH    +  +  E   + +E FEAEE    +K +   KGP+    
Sbjct: 10391 EEGEFHEVEEFIKLEQHRVEEEHRV--EKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEK 10448

Query: 428   -LPP--PATPRLEPRGPPA--PEV-----VKQPVYLPS--KAGPKAQTACLPP----PRP 471
              +PP  P T  +  + PPA  PEV     V++ V +P   +  P      LPP    P  
Sbjct: 10449 IIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEK 10508

Query: 472   QRPVTKARRPPPQPHRRAET------KARLPPPRPQRPA---------------ETKVPE 510
             + PV  A++P   P +  E       + ++P P P++P                E KVPE
Sbjct: 10509 KVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPE 10568

Query: 511   EIPPEVVQEYVDIME--ELLGPSLGATGEPEKQREEGKVKQPQEEDWTPPD 559
              IPP+      ++ E  + + P       P K+ E   VK P+      P+
Sbjct: 10569 AIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPE 10619



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 55/230 (23%), Positives = 99/230 (43%), Gaps = 49/230 (21%)

Query: 367  LARRKPTMTLEEGLWRAMRE--WQHTSNFDRMIF--YEMAEKFLEFEAEEEMQIQKSQWM 422
            +  ++   TLEE      RE  ++    +D   F  YE  E++ ++E  EE + ++ +  
Sbjct: 9723 MEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYE-- 9780

Query: 423  KGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPV-TKARRP 481
            +  + +  P  P                  +P K            P P+ PV TK + P
Sbjct: 9781 EHEEYITEPEKP------------------IPVK------------PVPEEPVPTKPKAP 9810

Query: 482  PPQPHRRA--ETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDI------MEELLGPSLG 533
            P +  ++A  E K  +P P+  +P   KVPEE P +V +E + I       E++  P+  
Sbjct: 9811 PAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEE-PKKVFEEKIRISITKREKEQVTEPAAK 9869

Query: 534  ATGEPEKQREEGKVKQPQEEDWTP---PDPGLLSYIDKLCSQKDFVTKVE 580
               +P++   E KV  P++E   P   P+       +++  +++ VT VE
Sbjct: 9870 VPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVE 9919



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 44/152 (28%), Positives = 63/152 (41%), Gaps = 30/152 (19%)

Query: 423   KGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPP 482
             K P+ +PP      +P  PP PEV + P     +  P+ +    PP +P+  VT  + P 
Sbjct: 10565 KVPEAIPP------KPESPP-PEVPEAP----KEVVPEKKVPAAPPKKPE--VTPVKVPE 10611

Query: 483   PQPHRRAETKARLPPPR---------PQRPA----ETKVPEEIPPEVVQEYVDIMEELLG 529
                    E K  +PPP+         P+ P     E KVPE IPP+      ++ EE   
Sbjct: 10612 APKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEE--- 10668

Query: 530   PSLGATGEPEKQ-REEGKVKQPQEEDWTPPDP 560
             P   A  EP  +  EE +   P +    P  P
Sbjct: 10669 PEEVALEEPPAEVVEEPEPAAPPQVTVPPKKP 10700



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 38/151 (25%), Positives = 62/151 (41%), Gaps = 17/151 (11%)

Query: 411   EEEMQIQKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQPV-YLPSKAGPKAQTACLPPP 469
             EE  +I   + +   +  P P     EP  PP P V ++P   +P K  P  +    PPP
Sbjct: 10805 EEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPP-PAVPEEPKKIIPEKKVPVIKKPEAPPP 10863

Query: 470   RPQRPVTKARRPPPQPHRRAETKARLPPPRPQRPAETKVPEE------IPPEVVQEYVDI 523
             +   P     +P  +P          PPP P  P +  V E+      IP + V E   +
Sbjct: 10864 KEPEPEKVIEKPKLKPR---------PPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQV 10914

Query: 524   MEELLGPSLGATGEPEKQREEGKVKQPQEED 554
              E++    L   G  +K R+    ++P+ ++
Sbjct: 10915 PEKVELTPLKVPGGEKKVRKLLPERKPEPKE 10945



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 44/173 (25%), Positives = 76/173 (43%), Gaps = 11/173 (6%)

Query: 411   EEEMQIQKSQWMKGPQCLPP--PATPRLEPRGP-PAPEVVKQPVYLPSKAGPKAQTACLP 467
             EE++ +   + ++ P    P  P  P  E + P PAP+ V+ P   P+K  P+     +P
Sbjct: 10014 EEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAP---PAKV-PEVPKKLIP 10069

Query: 468   PPRPQRPVTKARRPPPQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEEL 527
               +   PV K    PP    +      +P   PQ   E    EEI PE  +E +   EE+
Sbjct: 10070 EEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQE-EEVLFEEEIVPE--EEVLPEEEEV 10126

Query: 528   LGPSLGATGEPEKQREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVE 580
             L        E E+   E +   P+EE+  PP+   +   ++   +++ + +V+
Sbjct: 10127 LPEEEEVLPEEEEVLPEEEEIPPEEEE-VPPEEEYVPEEEEFVPEEEVLPEVK 10178



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 39/156 (25%), Positives = 62/156 (39%), Gaps = 31/156 (19%)

Query: 428   LPPPATPRLEP-RGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRP--VTKARRPPPQ 484
             +PPP  P + P + P  P+       +P    PK ++   PP  P+ P  V   ++ P  
Sbjct: 10540 VPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESP--PPEVPEAPKEVVPEKKVPAA 10597

Query: 485   PHRRAET----------------KARLPPPRPQRPAETKVPE----EIPPEVVQEYVDIM 524
             P ++ E                 K  +PPP+      TKVPE     +P + V E +   
Sbjct: 10598 PPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPK 10657

Query: 525   EELLGPSLGATGEPEKQREEGKVKQPQEEDWTPPDP 560
              E   P      E  ++ EE  +++P  E    P+P
Sbjct: 10658 PESPPP------EVFEEPEEVALEEPPAEVVEEPEP 10687



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 51/199 (25%), Positives = 80/199 (40%), Gaps = 35/199 (17%)

Query: 423   KGPQCLPPPATPRLEPRGPPAPEVVKQP------------VYLPSKAGPKAQTACLPPPR 470
             K P+ +PP      +P  PP PEV ++P            V  P  A P   T  +PP +
Sbjct: 10649 KVPEAIPP------KPESPP-PEVFEEPEEVALEEPPAEVVEEPEPAAPPQVT--VPPKK 10699

Query: 471   P----QRPVTKARRPPPQPHRRAETKARLPPPR------PQRPAE--TKVPEEIPPEVVQ 518
             P    + P   A++P   P +  E    + P +      P++P     KVP E+P EVV 
Sbjct: 10700 PVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVP-EVPKEVVP 10758

Query: 519   E-YVDIMEELLGPSLGATGEPEKQREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVT 577
             E  V + ++   P       P+K   E K   P  E    P P +    +++  +++   
Sbjct: 10759 EKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAP 10818

Query: 578   KVEAVIHPQFLEELLSPDP 596
             + E  +     EE   P P
Sbjct: 10819 EEEKPVPVAEEEEPEVPPP 10837



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 89/426 (20%), Positives = 155/426 (36%), Gaps = 94/426 (22%)

Query: 155  PAPGPAHGPLLVTAGAPPGGPLVLSTFPSTPLVTEQDGCSPSGAGASNVFVQMRTEVGPV 214
            P P P   P      APP  P V    P  P+  E+            V V  + E  P 
Sbjct: 9330 PVPVPKKEP-----AAPPKVPEV----PKKPVPEEK----------IPVPVAKKKEAPPA 9370

Query: 215  KAAQAQTLVLTQAPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWS 274
            K  + Q  V+T+  +       +      PPP        VP +  + V   +       
Sbjct: 9371 KVPEVQKGVVTEEKIT-----IVTQREESPPP-------AVPEIPKKKVPEERKPVPRKE 9418

Query: 275  QGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGESSLASSQAKAPPDDSCNPRSVYENFR 334
            + +P PPP  PA    P+  +  A P P              KAPP     PR+      
Sbjct: 9419 EEVP-PPPKVPALPKKPVPEEKVAVPVPVAK-----------KAPP-----PRAEVSKKT 9461

Query: 335  LWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFD 394
            + +  + +A   L           F +P    + R + +         A  EW ++   +
Sbjct: 9462 VVEEKRFVAEEKLS----------FAVPQRVEVTRHEVS---------AEEEWSYSEEEE 9502

Query: 395  RMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPA-----TPRLEPRGPPAPEVVKQ 449
             +      E+  E E EEE ++ + + M+ P+           + R+E       E  ++
Sbjct: 9503 GVSISVYREE--EREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEK 9560

Query: 450  PVYLPSKAGPKAQTACLPPPR-----PQRPVTKARRPPPQPHRRAETKARLPPPR-PQRP 503
             + L  K   K +    PPP      P++ V + + P P P      K ++PPP+ P+ P
Sbjct: 9561 KIVLKPKIPAKIEE---PPPAKVPEAPKKIVPEKKVPAPVPK-----KEKVPPPKVPEEP 9612

Query: 504  AETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPE------KQREEGKVKQPQEEDWTP 557
             +    +++PP+V++    +  ++    +  T E +      K+    K + P+E     
Sbjct: 9613 KKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAV 9672

Query: 558  PDPGLL 563
            P+  +L
Sbjct: 9673 PEEKVL 9678



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 44/188 (23%), Positives = 83/188 (44%), Gaps = 17/188 (9%)

Query: 432   ATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHRRAET 491
             A P   P  P  PE  K PV +P K  P        P  P++PV + + P P P +    
Sbjct: 9973  APPAKVPEVPKKPEE-KVPVLIPKKEKPPPAKV---PEVPKKPVPEEKVPVPVPKKVEAP 10028

Query: 492   KARLPPPRPQRPAETKVPEEIPPEV---VQEYVDIMEELLGPSLGATGEPEKQREEGKVK 548
              A++P    +   E KVP   P +V     +  ++ ++L+      T  P+K  E    K
Sbjct: 10029 PAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKV-EAPPPK 10087

Query: 549   QPQEEDWTP-----PDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLAL 603
              P++ +  P     P    + + +++  +++ + + E V+  +  EE+L  + ++  L  
Sbjct: 10088 VPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEE--EEVLPEEEEV--LPE 10143

Query: 604   SQDLEQEE 611
              +++  EE
Sbjct: 10144 EEEIPPEE 10151



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 73/328 (22%), Positives = 118/328 (35%), Gaps = 63/328 (19%)

Query: 282   PPPPAAQLP---------PIVSQGNAGPWPQGAHGESSLASSQAKA--PPDDSCNPRSVY 330
             PPP   + P         P++ +  A P P+    E  +   + K   PP     P+   
Sbjct: 10835 PPPAVPEEPKKIIPEKKVPVIKKPEAPP-PKEPEPEKVIEKPKLKPRPPPPPPAPPKEDV 10893

Query: 331   ENFRLWQHYKPLARRHLP---QSPDTEALSCFLIP-----VLRSLARRKPTMTLEEGLWR 382
             +  +++Q  K + ++ +P   Q P+   L+   +P     V + L  RKP    E  L  
Sbjct: 10894 KE-KIFQ-LKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKS 10951

Query: 383   AMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPRGPP 442
              +R+                      E E +++ +K + +K P    PP    +E     
Sbjct: 10952 VLRKRPE-------------------EEEPKVEPKKLEKVKKPAVPEPPPPKPVEE--VE 10990

Query: 443   APEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHRRAETKARLPPPRPQR 502
              P V K+   +P           +P P P+          P+P   AE K   PPP    
Sbjct: 10991 VPTVTKRERKIPEPTKVPEIKPAIPLPAPE----------PKPKPEAEVKTIKPPPVEPE 11040

Query: 503   PAETKVPEEIPPEVVQEYVDI---MEELLGPSLGATGEPEKQ----REEGKVKQPQEEDW 555
             P     P  +P  VV +  +     EE   P     G P+K       E +  +P     
Sbjct: 11041 PTPIAAPVTVP--VVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGE 11098

Query: 556   TPPDPGLLSYIDKLCSQKDFVTKVEAVI 583
              PPD    +Y  K    K FV +++ +I
Sbjct: 11099 KPPDEAPFTYQLKAVPLK-FVKEIKDII 11125



 Score = 38.5 bits (88), Expect = 0.019
 Identities = 44/165 (26%), Positives = 71/165 (43%), Gaps = 25/165 (15%)

Query: 394   DRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPRGPP-APEVVKQPVY 452
             ++ I     E+ L  E  EE + +     + P+   PP+   +E   PP  PEV+K    
Sbjct: 10221 EKRIILPKEEEVLPVEVTEEPEEEPISEEEIPE--EPPSIEEVEEVAPPRVPEVIK---- 10274

Query: 453   LPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHRRAETKARLPPPRPQRPAETKVPEEI 512
                KA P+A T          PV K    PP    +   + ++P P  ++ A      E+
Sbjct: 10275 ---KAVPEAPT----------PVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEV 10321

Query: 513   PPEVVQEYVDI-MEELLGPSLGATGEPEKQ----REEGKVKQPQE 552
             P +V ++ V +  +E + P+ G T   EK     R+E  VK+  E
Sbjct: 10322 PKKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLE 10366



 Score = 34.3 bits (77), Expect = 0.36
 Identities = 38/129 (29%), Positives = 54/129 (41%), Gaps = 36/129 (27%)

Query: 428  LPPPATPRLEPRGPPA-----PEVVKQPVYLPSK----------------------AGPK 460
            +PPP  P  EP+ P       P+V+K    LP+K                      A PK
Sbjct: 9603 VPPPKVPE-EPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPK 9661

Query: 461  AQTACLPPPRPQRPVTKARRPPPQPHRRAETKARLPPPRPQRPAETKVPEEIP---PEVV 517
            A+     P  P+R V + +    +P R  E  A++   R +   E KV  E P   P+ +
Sbjct: 9662 ARV----PEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPI 9717

Query: 518  QEYVDIMEE 526
            +E V IMEE
Sbjct: 9718 KE-VTIMEE 9725



 Score = 34.3 bits (77), Expect = 0.36
 Identities = 33/115 (28%), Positives = 51/115 (44%), Gaps = 8/115 (6%)

Query: 409   EAEEEMQIQKSQWMKGPQCLP--PPATPRLEPRGPPAPEVVKQPVYLPSKA-GPKAQTAC 465
             E EEE   ++ +++   + +P  P   P + PR P   E  K+PV +P K   P A+   
Sbjct: 9924  EEEEEYIHEEEEFITEEEVVPVIPVKVPEV-PRKPVPEE--KKPVPVPKKKEAPPAKVPE 9980

Query: 466   LPP-PRPQRPVTKARRPPPQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQE 519
             +P  P  + PV   ++  P P +  E   + P P  + P       E PP  V E
Sbjct: 9981  VPKKPEEKVPVLIPKKEKPPPAKVPEVPKK-PVPEEKVPVPVPKKVEAPPAKVPE 10034



 Score = 33.5 bits (75), Expect = 0.61
 Identities = 27/90 (30%), Positives = 33/90 (36%), Gaps = 15/90 (16%)

Query: 410 AEEEMQIQKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPP 469
           A  EM I  +   + P   PP   P+ + R P  P +             KAQ A    P
Sbjct: 235 ATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPPSIAA-----------KAQLARQQSP 283

Query: 470 RPQR----PVTKARRPPPQPHRRAETKARL 495
            P R    PV   R P P P R     AR+
Sbjct: 284 SPIRHSPSPVRHVRAPTPSPVRSVSPAARI 313



 Score = 33.5 bits (75), Expect = 0.61
 Identities = 33/138 (23%), Positives = 56/138 (40%), Gaps = 27/138 (19%)

Query: 398  FYEMAEKFLEFEAE--------EEMQIQKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQ 449
            +YE  E + E E E        E +Q+QK  + +  +   P   P  E + PP P+V+K+
Sbjct: 9126 YYEREEGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVP--EKKAPPPPKVIKK 9183

Query: 450  PVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHRRAETKARLPPPRPQR-PAETKV 508
            PV                  + ++   +      Q  +  E   ++ P +P R P + +V
Sbjct: 9184 PVI----------------EKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEV 9227

Query: 509  PEEIPPEVVQEYVDIMEE 526
             E   P V  + + I EE
Sbjct: 9228 IEVKVPAVHTKKMVISEE 9245


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
           sapiens]
          Length = 2715

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 46/146 (31%), Positives = 60/146 (41%), Gaps = 18/146 (12%)

Query: 425 PQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKAR---RP 481
           P  LPPP+T    P  PP P  V  P  LPS   P AQ      P P  P T +R   RP
Sbjct: 414 PPPLPPPSTSPPPPLCPPPPPPVSPPP-LPSPPPPPAQEEQEESPPPVVPATCSRKRGRP 472

Query: 482 PPQPHRRAETKAR------LPPPRPQRPAETKVPEEIPPEVVQE---YVDIMEELLGPSL 532
           P  P +RAE +A         PP P     T  P E  P V  +   ++  + + + P +
Sbjct: 473 PLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVV 532

Query: 533 GATGE-----PEKQREEGKVKQPQEE 553
            A        P +  +E   K P+ E
Sbjct: 533 SARSSRVIKTPRRFMDEDPPKPPKVE 558



 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 94/371 (25%), Positives = 134/371 (36%), Gaps = 63/371 (16%)

Query: 278 PLPPPPPPAAQLPPIVSQGNAGPWPQGAHGESSLASSQAKAPPD---DSCNPRSVYENFR 334
           PL PPPPP    PP+ S     P P  A  E      Q ++PP     +C+ +       
Sbjct: 427 PLCPPPPPPVSPPPLPS-----PPPPPAQEE------QEESPPPVVPATCSRKRGRPPLT 475

Query: 335 LWQHYKPLARRHLPQ--SPDTEALSCFLIPVLRSLARRKPTMTLEEGLWRAMREWQHTSN 392
             Q  +  A R  P+  SP T   S              P  T      R       ++ 
Sbjct: 476 PSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSAR 535

Query: 393 FDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPAT--PRLEPRGPPAPEVVKQP 450
             R+I  +   +F++ +  +  +++ S  ++ P    PP    P   P  P AP     P
Sbjct: 536 SSRVI--KTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTP 593

Query: 451 VYLPSKAGP---------KAQTACLPPPRPQRPVTKARRPPPQPHRRAETKARLPPPRP- 500
           V LP K             + T  LPPP P  P      PPP P          PPP P 
Sbjct: 594 VPLPEKRRSILREPTFRWTSLTRELPPPPPAPP------PPPAPS---------PPPAPA 638

Query: 501 ---QRPAETKVPEEIPPEVVQEYVDIMEELL-GPSLGATGEPEKQREEGKVKQPQEEDWT 556
              +RP   + P+  P E    ++ I E +L  P LGA   PE +        P ++   
Sbjct: 639 TSSRRPLLLRAPQFTPSEA---HLKIYESVLTPPPLGAPEAPEPE------PPPADDSPA 689

Query: 557 PPDPGLLSYIDKLCSQK---DFVTKVEAVIHPQFLEELLSPDPQMDFLALSQDLEQEEGL 613
            P+P  +   + L   +      T V+A + P      LS  PQ     L Q L+  +  
Sbjct: 690 EPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHG-APALSNGPQTQ-AQLLQPLQALQTQ 747

Query: 614 TLAQGAPSDAP 624
            L Q  P   P
Sbjct: 748 LLPQALPPPQP 758



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 36/119 (30%), Positives = 41/119 (34%), Gaps = 11/119 (9%)

Query: 400 EMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGP 459
           E  EK     AEE M   + +  K P   PPP TP      PP P     P   P    P
Sbjct: 377 EGEEKEERAVAEEMMPAAEKEEAKLP---PPPLTPPAPSPPPPLPPPSTSP---PPPLCP 430

Query: 460 KAQTACLPPPRPQRPVTKARR-----PPPQPHRRAETKARLPPPRPQRPAETKVPEEIP 513
                  PPP P  P   A+      PPP        K   PP  P + AE +     P
Sbjct: 431 PPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGP 489



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 78/349 (22%), Positives = 113/349 (32%), Gaps = 72/349 (20%)

Query: 278 PLPPPPPPAAQL------PPIV-------------------SQGNAGPWPQGAHGESSLA 312
           PLP PPPP AQ       PP+V                    +  A   P+G    +   
Sbjct: 440 PLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTP 499

Query: 313 SSQAKAPPDDSCN--PRSVYENFRLWQHYKPLA-----------RRHLPQSPDTEALSCF 359
           S+    PP+DS    P+S      + Q   P+            RR + + P        
Sbjct: 500 STATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPP-KVE 558

Query: 360 LIPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKS 419
           + PVLR      P +  E              +  R          L  +    ++    
Sbjct: 559 VSPVLRPPITTSPPVPQEPA---------PVPSPPRAPTPPSTPVPLPEKRRSILREPTF 609

Query: 420 QWMKGPQCLPPPAT---PRLEPRGPPAPE-------VVKQPVYLPSKAGPKAQTACLPPP 469
           +W    + LPPP     P   P  PPAP        +++ P + PS+A  K   + L PP
Sbjct: 610 RWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPP 669

Query: 470 RPQRPVTKARRPPPQPHRRAETKAR-------LPPPRPQRPAETKVPEEIPPE---VVQE 519
               P      PPP     AE + R       L  PR      T V  E+ P     +  
Sbjct: 670 PLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSN 729

Query: 520 YVDIMEELLGPSLGATGEPEKQREEGKVKQPQEEDWTPPDPGLLSYIDK 568
                 +LL P        + Q     +  PQ +   PP P  +  ++K
Sbjct: 730 GPQTQAQLLQPLQAL----QTQLLPQALPPPQPQLQPPPSPQQMPPLEK 774



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 36/122 (29%), Positives = 44/122 (36%), Gaps = 33/122 (27%)

Query: 426  QCLPPPATPRLEPRGPPAPEV-----VKQPVY--------------LPSKAGPKAQTACL 466
            Q L PP  P      PPAP       +K P Y              LPS   P + T  +
Sbjct: 1839 QNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHI 1898

Query: 467  P----------PPRPQRPVTKARRPPP----QPHRRAETKARLPPPRPQRPAETKVPEEI 512
            P          P R +RP   A RPPP     P  +   + R+PPP     A T    E+
Sbjct: 1899 PTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGEL 1958

Query: 513  PP 514
             P
Sbjct: 1959 AP 1960



 Score = 38.5 bits (88), Expect = 0.019
 Identities = 53/208 (25%), Positives = 69/208 (33%), Gaps = 56/208 (26%)

Query: 117  SAQPEGMASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPL 176
            S  P    +NG+ P    G+TA+P      F  LP                 GAP    L
Sbjct: 2135 SLPPAPPLANGSQP--SQGLTASPADPTRTFAWLP-----------------GAPGVRVL 2175

Query: 177  VLSTFPSTPLVTEQDGCSPSGAGASNVFVQMRTE----VGPVKAAQAQTLVLTQAPLVWQ 232
             L   P  P          +  G   VFV+M  E      PVK       +   AP  W 
Sbjct: 2176 SLGPAPEPPKPATSKIILVNKLG--QVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSW- 2232

Query: 233  APGALCGGVVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPI 292
                       PP  LL   PVV                    G+  P PPPP   L  +
Sbjct: 2233 ---------TLPPGPLLGVLPVV--------------------GVVRPAPPPPPPPLTLV 2263

Query: 293  VSQGNAGPWPQGAHGESSLASSQAKAPP 320
            +S G A P P+ A     +++   ++PP
Sbjct: 2264 LSSGPASP-PRQAIRVKRVSTFSGRSPP 2290



 Score = 36.6 bits (83), Expect = 0.072
 Identities = 48/166 (28%), Positives = 58/166 (34%), Gaps = 43/166 (25%)

Query: 400 EMAEKFLEFEAEEEMQIQKSQWM---KGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSK 456
           E  EK  E E +EE  + +       K    LPPP      P  PPAP         P  
Sbjct: 370 EEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPP------PLTPPAPS--------PPP 415

Query: 457 AGPKAQTACLPP--PRPQRPVTKARRPPPQPHRRAETKARLPPPRPQRPAETKVPEEIPP 514
             P   T+  PP  P P  PV+    PPP P          PPP P +  +    EE PP
Sbjct: 416 PLPPPSTSPPPPLCPPPPPPVS----PPPLPS---------PPPPPAQEEQ----EESPP 458

Query: 515 EVVQEYVDIMEELLGPSLGATGEPEKQREEGKVKQPQEEDWTPPDP 560
            VV               G       QR E +  +   E  +PP P
Sbjct: 459 PVV-------PATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTP 497



 Score = 33.9 bits (76), Expect = 0.47
 Identities = 53/215 (24%), Positives = 76/215 (35%), Gaps = 49/215 (22%)

Query: 423  KGPQCLPPPATPRLEP-RGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRP 481
            + P+  P P  PR     G P  EVV  P       GP+ Q + L     +R V +  RP
Sbjct: 1034 ESPEASPGPPGPRRGAGAGGPREEVVAHP-------GPEEQDSLLQRKSARRCVKQ--RP 1084

Query: 482  ---------------PPQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEE 526
                           PP P RR   +  LP P P+  +  + P   P   ++    + ++
Sbjct: 1085 SYDIFEDSDDSEPGGPPAPRRRTPRENELPLPEPEEQSRPRKPTLQPVLQLKARRRLDKD 1144

Query: 527  LLGPS------LGATGEPEKQREEGKVKQPQEED------W-------TPPDPGLLSYID 567
             L P        G TG+ +      +V+   +ED      W           PG    + 
Sbjct: 1145 ALAPGPFASFPNGWTGKQKSPDGVHRVRVDFKEDCDLENVWLMGGLSVLTSVPGGPPMVC 1204

Query: 568  KLCSQKDFVTKVEAVI-----HPQFLEELLSPDPQ 597
             LC+ K     V   +     HP  LEE   P PQ
Sbjct: 1205 LLCASKGLHELVFCQVCCDPFHPFCLEEAERPLPQ 1239



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 21/54 (38%), Positives = 24/54 (44%), Gaps = 4/54 (7%)

Query: 435  RLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRP---QRPVTKARRPPPQP 485
            ++   G P P  VKQP  LP    P A T+   PP P     PV    RP P P
Sbjct: 2203 KMAGEGEPVPPPVKQPP-LPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPP 2255


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 45/134 (33%), Positives = 50/134 (37%), Gaps = 15/134 (11%)

Query: 430 PPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPP-----Q 484
           PPA PR  PRG PA      P   P+   P A  A   P R  R    A   PP     Q
Sbjct: 108 PPAPPRA-PRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQ 166

Query: 485 PHRRAETKARL--PPPRPQRP---AETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPE 539
           P  RA+  A L  PPP P  P   A    P   PP  V       E  L P       P+
Sbjct: 167 PGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVA----AREPPLPPPPQPPAPPQ 222

Query: 540 KQREEGKVKQPQEE 553
           +Q+      QP  E
Sbjct: 223 QQQPPPPQPQPPPE 236



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 36/125 (28%), Positives = 48/125 (38%), Gaps = 21/125 (16%)

Query: 425 PQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQ 484
           P   PPPA     P  PPA      P   P  A    +    PPP+P  P  + + PPPQ
Sbjct: 176 PLAAPPPA-----PAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQ 230

Query: 485 PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 544
           P          PPP        +      P  ++E V      LG S GA G   + R +
Sbjct: 231 PQ---------PPP---EGGAVRAGGAARPVSLREVV----RYLGGSGGAGGRLTRGRVQ 274

Query: 545 GKVKQ 549
           G +++
Sbjct: 275 GLLEE 279



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 36/118 (30%), Positives = 44/118 (37%), Gaps = 28/118 (23%)

Query: 423 KGPQCLPPPATPRLEPRGPPAPEVV-----------------KQPVYLPSKAGPKAQTA- 464
           +G       A P   P  PP P  V                   P   P++ GP+AQ A 
Sbjct: 116 RGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAA 175

Query: 465 --CLPPPRPQRPVTKARRPPPQPHRR-----AETKARLPPPRPQRPAETKVPEEIPPE 515
               PPP P  P   A  PP  P R      A  +  LPPP PQ PA  +  +  PP+
Sbjct: 176 PLAAPPPAPAAPPAVA--PPAGPRRAPPPAVAAREPPLPPP-PQPPAPPQQQQPPPPQ 230



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 42/145 (28%), Positives = 47/145 (32%), Gaps = 30/145 (20%)

Query: 153 TTPAP--GPAHGPLLVTAGAPPGGPLVLSTFPSTPLVTEQDGCSPSGAGASNVFVQMRTE 210
           T PAP   P   P    A APP  P      P  P+       +P  A A+         
Sbjct: 107 TPPAPPRAPRGAPAAAAAAAPP--PTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGP 164

Query: 211 VGPVKAAQAQTLVLTQAPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMAAQVVGGTQACE 270
             P   AQ        APL    P       V PP     A P  P +AA+         
Sbjct: 165 AQPGPRAQRA------APLAAPPPAPAAPPAVAPPAGPRRAPP--PAVAAREP------- 209

Query: 271 GGWSQGLPLPPPP----PPAAQLPP 291
                  PLPPPP    PP  Q PP
Sbjct: 210 -------PLPPPPQPPAPPQQQQPP 227



 Score = 35.4 bits (80), Expect = 0.16
 Identities = 21/51 (41%), Positives = 24/51 (47%), Gaps = 11/51 (21%)

Query: 424 GPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRP 474
           GP+  PPPA    EP  PP P    QP   P +  P       PPP+PQ P
Sbjct: 195 GPRRAPPPAVAAREPPLPPPP----QPPAPPQQQQP-------PPPQPQPP 234



 Score = 34.7 bits (78), Expect = 0.27
 Identities = 46/169 (27%), Positives = 52/169 (30%), Gaps = 42/169 (24%)

Query: 127 GAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSTFPSTPL 186
           GA P   P   A  G   +   A P  TPAP P   P  V A AP   P   +   + P 
Sbjct: 105 GATPPAPP--RAPRGAPAAAAAAAPPPTPAPPPPPAP--VAAAAPARAPRAAAAAATAP- 159

Query: 187 VTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGGVVCPPP 246
                   PS   A         + GP     A       AP    A     G    PPP
Sbjct: 160 --------PSPGPA---------QPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPP 202

Query: 247 LLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPP----PPPPAAQLPP 291
            + A  P +P                     P PP    PPPP  Q PP
Sbjct: 203 AVAAREPPLPPPPQP----------------PAPPQQQQPPPPQPQPPP 235


>gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo sapiens]
          Length = 1086

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 98/417 (23%), Positives = 143/417 (34%), Gaps = 90/417 (21%)

Query: 131  VLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSTFPSTPLVTEQ 190
            ++G GV A P    + +  +P     P P    L +    P GG                
Sbjct: 732  LVGAGVPAGPSQGQTNYAFVPEQARPPPPLEDNLFLP---PQGG---------------- 772

Query: 191  DGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGG---VVCPPPL 247
             G  PS A  + +F          +A Q + +   QAP    AP    GG      PP +
Sbjct: 773  -GKPPSSAQTAEIF----------QALQQECMRQLQAPAGSPAPSPSPGGDDKPQVPPRV 821

Query: 248  LLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHG 307
             +   P  P +        +     W    P P  PP      P+  QG+  P P    G
Sbjct: 822  PIPPRPTRPHVQLSPAPPGEEETSQW----PGPASPPRVPPREPLSPQGSRTPSPLVPPG 877

Query: 308  ESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSL 367
             S L       PP  S +P       + +      A   + Q+P   A  C ++P++R  
Sbjct: 878  SSPL-------PPRLSSSPGKTMPTTQSFASDPKYATPQVIQAPGPRAGPC-ILPIVRDG 929

Query: 368  ARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQC 427
             +   T               +    +R  + E  ++FL     E    ++   +  P  
Sbjct: 930  KKVSST--------------HYYLLPERPSYLERYQRFL----REAQSPEEPTPLPVPLL 971

Query: 428  LPPPATPRLEPRGPPAPEVVKQPVYLPSKA-GPKAQTACLPPPRPQRPVTKARRPPPQPH 486
            LPPP+TP      P AP    +P  +P  A  PKA  +             AR PPP+  
Sbjct: 972  LPPPSTP-----APAAPTATVRP--MPQAALDPKANFS------TNNSNPGARPPPPR-- 1016

Query: 487  RRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQRE 543
                  ARL    PQR      PE   P    + + ++E+L G  L   GE  K  E
Sbjct: 1017 ----ATARL----PQRGCPGDGPEAGRP---ADKIQMVEQLFGLGLRPRGECHKVLE 1062



 Score = 30.0 bits (66), Expect = 6.7
 Identities = 18/57 (31%), Positives = 23/57 (40%), Gaps = 2/57 (3%)

Query: 431 PATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVT--KARRPPPQP 485
           P  P L P  P   ++      L  +  P++ T  LP P    PV    AR  PP P
Sbjct: 655 PVVPALRPCAPSLAQLAMDACSLLDETPPQSPTRALPRPLHPTPVVDWDARPLPPPP 711


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 85/359 (23%), Positives = 140/359 (38%), Gaps = 74/359 (20%)

Query: 278 PLPPP--------PP--PAAQLPPIVSQGNAGPWPQGAHGESSLASSQAKAPPDDSCNPR 327
           P+PPP        PP  P   +P + S  +AGP P      S+     A+  P  + N  
Sbjct: 650 PVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTANHL 709

Query: 328 SVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEGLWRAMREW 387
            +     +      +  R LP  P+         P+L       PT+  +E     +   
Sbjct: 710 GLSVPGLV-----SVPPRLLP-GPENHRAGSNEDPILAPSGTPPPTIPPDETFGGRVPRP 763

Query: 388 QHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPP-----ATPRLEPRGPP 442
               ++D+    ++ E  LE ++++ + I      +G   LPPP       P + P GPP
Sbjct: 764 AFV-HYDKEEASDV-EISLESDSDDSVVIVP----EGLPPLPPPPPSGATPPPIAPTGPP 817

Query: 443 --APEVV--KQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHRRAETKARLPPP 498
             +P V   ++P  LP+  GP      LPPP P         PPP P         LPPP
Sbjct: 818 TASPPVPAKEEPEELPAAPGP------LPPPPPP--------PPPVP-----GPVTLPPP 858

Query: 499 RPQRPAETKVPEEIP----PEVVQEYVDIMEELLGPSLGATGEPEKQREEGKVKQPQEED 554
           +        VPE  P    P  ++E + ++   +  S     E E++ EE + ++ +EED
Sbjct: 859 Q-------LVPEGTPGGGGPPALEEDLTVIN--INSSDEEEEEEEEEEEEEEEEEEEEED 909

Query: 555 WTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLALSQDLEQEEGL 613
           +   +     Y ++           E     +F EE    + +++     +D E+EE L
Sbjct: 910 FEEEEEDEEEYFEE-----------EEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEEL 957



 Score = 37.0 bits (84), Expect = 0.055
 Identities = 55/207 (26%), Positives = 75/207 (36%), Gaps = 44/207 (21%)

Query: 123 MASNGAYPVLGPGVTANPGT-------SLSV---FTALPFTTPAP-----GPAHGPLLVT 167
           M S G  P  GP  +A PG         LSV    +  P   P P     G    P+L  
Sbjct: 683 MPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAP 742

Query: 168 AGAPPGGPLVLSTFPSTPLVTEQDGCSPSGA-------GASNVFVQMRTEVGPVKAAQAQ 220
           +G PP         P+ P      G  P  A        AS+V + + ++          
Sbjct: 743 SGTPP---------PTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESD-------SDD 786

Query: 221 TLVLTQAPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLP 280
           ++V+    L    P    G    PPP+    AP  P  A+  V   +  E   +   PLP
Sbjct: 787 SVVIVPEGLPPLPPPPPSGAT--PPPI----APTGPPTASPPVPAKEEPEELPAAPGPLP 840

Query: 281 PPPPPAAQLPPIVSQGNAGPWPQGAHG 307
           PPPPP   +P  V+       P+G  G
Sbjct: 841 PPPPPPPPVPGPVTLPPPQLVPEGTPG 867



 Score = 34.3 bits (77), Expect = 0.36
 Identities = 30/117 (25%), Positives = 44/117 (37%), Gaps = 22/117 (18%)

Query: 425  PQCLPPPATP-RLEPRGPPAPEV---VKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARR 480
            P  LPPP +P +++P   P P +   V++P     +    A T        Q  V +   
Sbjct: 983  PPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGE 1042

Query: 481  PP---PQPHRRAETKARLPP---------------PRPQRPAETKVPEEIPPEVVQE 519
             P   P P    E +   PP               P P+ PAE ++  E   E +QE
Sbjct: 1043 SPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQE 1099


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 97/430 (22%), Positives = 145/430 (33%), Gaps = 111/430 (25%)

Query: 120  PEGMASNGAY--PVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAG-------- 169
            P+ + S GAY  P   PG+      + +   +L    P P  +  P+L            
Sbjct: 663  PQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPG 722

Query: 170  --APPGG-----------PLVLSTFPSTPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKA 216
              APPG            P VL+  P  PL        P  A AS V             
Sbjct: 723  QPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAP---------- 772

Query: 217  AQAQTLVLTQAPL--VWQAPGALCGGVVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWS 274
            AQ + L + QAPL  + Q P  +    V PP   LA    +P     +   T        
Sbjct: 773  AQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTAT-------- 824

Query: 275  QGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGESSLASSQAKAPPDDSCNPRSVYENFR 334
                +PP PPP    P ++    A P P  +    +L     K P               
Sbjct: 825  ----VPPVPPPQYFSPAVILPSLAAPLPPAS---PALPLQAVKLPHPPGA---------- 867

Query: 335  LWQHYKPLA---RRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEGLWRAMREWQHTS 391
                  PLA   R  +P +P T       IP+L         +++   + +   +  + +
Sbjct: 868  ------PLAMPCRTIVPNAPAT-------IPLLAVAPPGVAALSIHSAVAQLPGQPVYPA 914

Query: 392  NFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQPV 451
             F +M             A  ++       ++  +  PP      +P  PP P +  QPV
Sbjct: 915  AFPQM-------------APTDVPPSPHHTVQNMRATPP------QPALPPQPTLPPQPV 955

Query: 452  YLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHRRAETKARLPPPRPQRPAETKVPEE 511
              P    P        P RP +PV      PPQP         + PP+P  P +  +P  
Sbjct: 956  LPPQPTLPPQPVLPPQPTRPPQPVL-----PPQP---------MLPPQPVLPPQPALP-- 999

Query: 512  IPPEVVQEYV 521
            + PE +Q ++
Sbjct: 1000 VRPEPLQPHL 1009



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 51/166 (30%), Positives = 67/166 (40%), Gaps = 22/166 (13%)

Query: 158  GPAHGPLLVTAGAPPGGPLVLSTFPSTPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKAA 217
            GP++ P     GAPP  PL  S+ P T L   QDG +P+ +          ++ G     
Sbjct: 1372 GPSNPP-----GAPPA-PLAPSSPPVTAL--PQDGAAPATSTMPEPASGTASQAGGPGTP 1423

Query: 218  QAQTLVL-TQAPLV--WQAPGALCGGVVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWS 274
            Q  T  L T  PL    +AP A+        PL++  AP  P   A       A      
Sbjct: 1424 QGLTSELETSQPLAETHEAPLAV-------QPLVVGLAPCTPAPEAASTRDASAPR---- 1472

Query: 275  QGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGESSLASSQAKAPP 320
            + LP P P P      P  + G   P    A G  SLA+SQ  +PP
Sbjct: 1473 EPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPP 1518



 Score = 37.4 bits (85), Expect = 0.042
 Identities = 34/128 (26%), Positives = 49/128 (38%), Gaps = 8/128 (6%)

Query: 428  LPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHR 487
            LPPPA       G P P + +    LP+  G  +      P  P  P       PPQP  
Sbjct: 1475 LPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTV-----PPQPPS 1529

Query: 488  RAETKARLPPPRPQRPAET--KVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG 545
              E+    PPPR      T   + E++   + QE+V       G  +   G+ +   E  
Sbjct: 1530 ALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPV-EVGDRDFTLEPL 1588

Query: 546  KVKQPQEE 553
            +  QP+ E
Sbjct: 1589 RGDQPRSE 1596



 Score = 33.1 bits (74), Expect = 0.79
 Identities = 37/129 (28%), Positives = 50/129 (38%), Gaps = 24/129 (18%)

Query: 430  PPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHRRA 489
            PP    L      A ++  QPVY P+     A T    PP P   V   R  PPQP    
Sbjct: 891  PPGVAALSIHSAVA-QLPGQPVY-PAAFPQMAPTDV--PPSPHHTVQNMRATPPQPALPP 946

Query: 490  E----------TKARLP-----PPRPQRPAETKVPEE--IPPEVV---QEYVDIMEELLG 529
            +           +  LP     PP+P RP +  +P +  +PP+ V   Q  + +  E L 
Sbjct: 947  QPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQ 1006

Query: 530  PSLGATGEP 538
            P L     P
Sbjct: 1007 PHLPEQAAP 1015


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 41/123 (33%), Positives = 49/123 (39%), Gaps = 24/123 (19%)

Query: 422 MKGPQCLPPPATPRLEPRGPP----------APEVVKQPVYLPSKAGPKAQTACLPP-PR 470
           M GP  L PP  P L P GPP          AP  ++ P  +P   GP  +   LPP P 
Sbjct: 407 MPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPP-GMPGLRGPLPR--LLPPGPP 463

Query: 471 PQRPVTKARRPPPQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGP 530
           P RP      PPP           LPP  P R    ++P   PP +      +M   L P
Sbjct: 464 PGRPPGPPPGPPP----------GLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVP 513

Query: 531 SLG 533
            LG
Sbjct: 514 PLG 516



 Score = 32.7 bits (73), Expect = 1.0
 Identities = 24/84 (28%), Positives = 26/84 (30%), Gaps = 5/84 (5%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHRR 488
           PPP  P   P GPP       P   P    P      +PPPRP        RPP  P   
Sbjct: 462 PPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRP-----GMMRPPLVPPLG 516

Query: 489 AETKARLPPPRPQRPAETKVPEEI 512
                  PP     P     P  +
Sbjct: 517 PAPPGLFPPAPLPNPGVLSAPPNL 540


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 104/407 (25%), Positives = 140/407 (34%), Gaps = 66/407 (16%)

Query: 143  SLSVFTALPFTTPA--PGPAHGPLLVTAGAP----PGGPLVLS--TFPSTPLVTEQDG-- 192
            S+ + ++LP + P   P PA  PL +   AP      GP +L+  T P  P+V    G  
Sbjct: 1432 SVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPP 1491

Query: 193  -CSPSGAGASNVFVQMRTEVGP-VKAAQAQTLVLTQAPLVWQAPG------ALCGGVVCP 244
              +PSGA  S   + +     P + ++Q     L  AP     PG        C  V+ P
Sbjct: 1492 SLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVP 1551

Query: 245  PPLLLAAAPVVPVMA-AQVVGGTQACEGGWSQGLPL------------PPPPPPAAQLPP 291
               L +  P  P  A AQ      A     +   PL            P P PP A LP 
Sbjct: 1552 ASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPV 1611

Query: 292  IVSQGNAGP------------WPQGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHY 339
            +     A P             P    G +SLAS+     P     P S  +        
Sbjct: 1612 LAPSPGAAPVLASSQTPVPVMAPSSTPG-TSLASASPVPAPTPVLAPSST-QTMLPAPVP 1669

Query: 340  KPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFY 399
             PL     P S  T AL+  L P   +L    P+ TL  G       +       + +  
Sbjct: 1670 SPLPS---PASTQTLALAPALAP---TLGGSSPSQTLSLGTGNPQGPFP-----TQTLSL 1718

Query: 400  EMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPRGP--PAPEVVKQPVYLPSKA 457
              A   +   A      Q      GP  L P  T  L P  P  PA  V   P +  + A
Sbjct: 1719 TPASSLVPTPA------QTLSLAPGPP-LGPTQTLSLAPAPPLAPASPVGPAPAHTLTLA 1771

Query: 458  GPKAQTACLPPPRPQRPVTKARRPPPQPHRRAETKARLPPPRPQRPA 504
             P + +A L  P   + +T +  P P     A     L P   Q PA
Sbjct: 1772 -PASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPA 1817



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 76/308 (24%), Positives = 104/308 (33%), Gaps = 47/308 (15%)

Query: 40   SGSCLMAEALHRTSPTPNSCPLPLPLCRMSGVLCSRNLFTFKFSLFQLDSGASGEPGHSL 99
            SG  L+       +P   + P P P    SG   S +  T   +     S +S  PGH L
Sbjct: 1468 SGPALLTSVTPPLAPVVPAAPGP-PSLAPSGASPSASALTLGLATAPSLS-SSQTPGHPL 1525

Query: 100  GLTLGFSYCGNCQTAVVSA------QPEGMAS---NGAYPVLGPGVTANPGTSLSVFTAL 150
             L    S+     + V  A          +AS   +   P         P +S S   A 
Sbjct: 1526 LLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALAT 1585

Query: 151  PFT----------TPAPGPAHGPLLVTAGAPPGGPLVLSTFPSTPLVTEQDGCSPSGAGA 200
            P             P+P P   PL V A +P   P++ S+    P++        S A A
Sbjct: 1586 PLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASA 1645

Query: 201  SNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMAA 260
            S V         PV A  +     TQ  L    P  L      P P       + P +A 
Sbjct: 1646 SPV-----PAPTPVLAPSS-----TQTMLPAPVPSPL------PSPASTQTLALAPALAP 1689

Query: 261  QVVGGTQACEGGWSQGLPLPPPP------PPAAQLPPIVSQGNA---GPWPQGAHGESSL 311
             + G + +       G P  P P       PA+ L P  +Q  +   GP P G     SL
Sbjct: 1690 TLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGP-PLGPTQTLSL 1748

Query: 312  ASSQAKAP 319
            A +   AP
Sbjct: 1749 APAPPLAP 1756



 Score = 31.6 bits (70), Expect = 2.3
 Identities = 30/102 (29%), Positives = 39/102 (38%), Gaps = 18/102 (17%)

Query: 430  PPATPRLEPRGPPAPEVVKQP-------VYL------PSKAGPKAQTACLPPPRPQRPVT 476
            P A P L P    AP  +  P       V++      PS+  P +  AC PPP    P  
Sbjct: 2451 PAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSSPACTPPPACTPP-- 2508

Query: 477  KARRPPPQPHRRAETKARL---PPPRPQRPAETKVPEEIPPE 515
             A  PPP         + L   PP  P   + T +P  + PE
Sbjct: 2509 PAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPE 2550



 Score = 30.8 bits (68), Expect = 3.9
 Identities = 49/183 (26%), Positives = 64/183 (34%), Gaps = 19/183 (10%)

Query: 112  QTAVVSAQPEGMASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPL-LVTAGA 170
            +T VV   P   A  G  PV  P     PG  LS   A P  TP P P   P  L+ + +
Sbjct: 1007 RTVVVVNNPR--APLGPVPVRPP-----PGPELS---AQP--TPGPVPQVLPASLMVSAS 1054

Query: 171  PPGGPLVLSTFPSTPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAP-- 228
            P G PL+ ++ P  P++       P+      V       +         TL L   P  
Sbjct: 1055 PAGPPLIPASRPPGPVLLPP--LQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPA 1112

Query: 229  LVWQAPGALCGGVVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQ 288
             V  +P    G      PL +      P  AA     T A     +  +P P P P    
Sbjct: 1113 PVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTAT--ATTTAVPAPTPAPQRLI 1170

Query: 289  LPP 291
            L P
Sbjct: 1171 LSP 1173



 Score = 30.8 bits (68), Expect = 3.9
 Identities = 29/104 (27%), Positives = 36/104 (34%), Gaps = 14/104 (13%)

Query: 424  GPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPP- 482
            GP  + PP  P L  +  P P     P  L   A P A    +P  RP  PV      P 
Sbjct: 1020 GPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSASP-AGPPLIPASRPPGPVLLPPLQPN 1078

Query: 483  --------PQPHRRAETKARLPPP----RPQRPAETKVPEEIPP 514
                    P P       +R P P    +P  PA  ++    PP
Sbjct: 1079 SGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPP 1122



 Score = 30.0 bits (66), Expect = 6.7
 Identities = 21/71 (29%), Positives = 27/71 (38%), Gaps = 4/71 (5%)

Query: 430  PPATPRLEPRGPPAPEVVKQPVYL-PSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHR- 487
            PPA  RL P  PP    + +P+ + P    P A              T    P P P R 
Sbjct: 1110 PPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRL 1169

Query: 488  --RAETKARLP 496
                + +ARLP
Sbjct: 1170 ILSPDMQARLP 1180


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 37/137 (27%), Positives = 51/137 (37%), Gaps = 13/137 (9%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPP----PRPQRPVTKARRPPPQ 484
           P P TP+      PAP   K+P   P+     A T    P    P+   P T     P  
Sbjct: 434 PAPTTPK-----KPAPTTPKEPA--PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 486

Query: 485 PHRRAETKA-RLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQRE 543
           P +   T   +L P  P++PA T  PEE+ P   +E      E   P+      P   +E
Sbjct: 487 PKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 545

Query: 544 EGKVKQPQEEDWTPPDP 560
                  +    TP +P
Sbjct: 546 PAPTTPKEPAPTTPKEP 562



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 36/135 (26%), Positives = 49/135 (36%), Gaps = 10/135 (7%)

Query: 429 PPPATPRLEPRGP--PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPH 486
           P P T +  P  P  P+P   K+P   P+     A T     P+   P T     P  P 
Sbjct: 403 PAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTT----PKKPAPTTPKEPAPTTPK 456

Query: 487 RRAETKARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG 545
             A T  + P P  P+ PA T  P+E  P   ++      E L P+      P    E  
Sbjct: 457 EPAPTTTKKPAPTTPKEPAPT-TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA 515

Query: 546 KVKQPQEEDWTPPDP 560
                +    TP +P
Sbjct: 516 PTTPEEPTPTTPEEP 530



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 32/135 (23%), Positives = 44/135 (32%), Gaps = 11/135 (8%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPP----PRPQRPVTKARRPPPQ 484
           P P TP+      PAP   K+P   P+     A T    P    P+   P T  +  P  
Sbjct: 442 PAPTTPK-----EPAPTTPKEPA--PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 494

Query: 485 PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 544
           P + A T    P P          PEE  P   +E      +   P+      P   +E 
Sbjct: 495 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 554

Query: 545 GKVKQPQEEDWTPPD 559
                 +    TP +
Sbjct: 555 APTTPKEPAPTTPKE 569



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 32/99 (32%), Positives = 41/99 (41%), Gaps = 13/99 (13%)

Query: 429 PPPATPRLEPRGP--PAPEVVKQPVYL----PSKAGPKAQTACLPPPRPQRPVTKARRPP 482
           P P T +  P  P  PAP   K+P       P+   PK  T    P  P+ P    + P 
Sbjct: 286 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT----PTTPKEPAPTTKEPA 341

Query: 483 PQ-PHRRAETKARLPPPR-PQRPAETKVPEEIPPEVVQE 519
           P  P   A T  + P P  P+ PA T  P+E  P   +E
Sbjct: 342 PTTPKEPAPTAPKKPAPTTPKEPAPT-TPKEPAPTTTKE 379



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 35/133 (26%), Positives = 48/133 (36%), Gaps = 14/133 (10%)

Query: 429 PPPATPRLEPRGP--PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPH 486
           P P T +  P  P  PAP   K     P +  P       P    +   T  + P P   
Sbjct: 232 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 291

Query: 487 RRAETKARLPPPR-PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG 545
           + A T  + P P  P++PA T  P+E  P   +E          P+     EP    +E 
Sbjct: 292 KSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKE----------PTPTTPKEPAPTTKEP 340

Query: 546 KVKQPQEEDWTPP 558
               P+E   T P
Sbjct: 341 APTTPKEPAPTAP 353



 Score = 37.4 bits (85), Expect = 0.042
 Identities = 24/89 (26%), Positives = 31/89 (34%), Gaps = 5/89 (5%)

Query: 429 PPPATPRLEPRGP----PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQ 484
           P P TP+ EP       P P  +K     P +  P    +    P+   P T     P  
Sbjct: 216 PTPTTPK-EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 274

Query: 485 PHRRAETKARLPPPRPQRPAETKVPEEIP 513
           P   A T  + P P   + A T   E  P
Sbjct: 275 PKEPAPTTTKEPAPTTTKSAPTTPKEPAP 303



 Score = 37.0 bits (84), Expect = 0.055
 Identities = 29/133 (21%), Positives = 45/133 (33%), Gaps = 8/133 (6%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPV-YLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHR 487
           P P TP+      PAP   K+P    P +  P  +      P+   P    +  P  P  
Sbjct: 309 PAPTTPK-----EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE 363

Query: 488 RAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKV 547
            A T  + P P   +      P+E  P   +      +E    +  +     K+      
Sbjct: 364 PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 423

Query: 548 KQPQEEDWTPPDP 560
           K+P     TP +P
Sbjct: 424 KEPAPT--TPKEP 434



 Score = 36.6 bits (83), Expect = 0.072
 Identities = 33/136 (24%), Positives = 47/136 (34%), Gaps = 5/136 (3%)

Query: 429 PPPATPRLE-PRGP--PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPV-TKARRPPPQ 484
           P P TP+   P  P  PAP   K+P     K      T    P  P+ P  T  +  P  
Sbjct: 340 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 399

Query: 485 PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 544
               A T  +  P  P+ P+ T   +E  P   +E      +   P+      P   +E 
Sbjct: 400 TKEPAPTTTKSAPTTPKEPSPT-TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 458

Query: 545 GKVKQPQEEDWTPPDP 560
                 +    TP +P
Sbjct: 459 APTTTKKPAPTTPKEP 474



 Score = 36.6 bits (83), Expect = 0.072
 Identities = 33/134 (24%), Positives = 47/134 (35%), Gaps = 7/134 (5%)

Query: 429 PPPATPRLEPRGP----PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQ 484
           P P TP+ EP       P+P   K+P    +K+ P       P      P T     P  
Sbjct: 364 PAPTTPK-EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 422

Query: 485 PHRRAETKARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQRE 543
               A T  + P P  P++PA T  P+E  P   +E      +   P+      P   +E
Sbjct: 423 TKEPAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKE 481

Query: 544 EGKVKQPQEEDWTP 557
                  +    TP
Sbjct: 482 TAPTTPKKLTPTTP 495



 Score = 36.6 bits (83), Expect = 0.072
 Identities = 40/142 (28%), Positives = 56/142 (39%), Gaps = 16/142 (11%)

Query: 429 PPPATPR----LEPRGPPAPEVVKQPV-YLPSKAGPKAQTACLPPPRPQRPV--TKARRP 481
           P P TP+      P+G  AP  +K+P    P K  PK     L P   + P   T  +  
Sbjct: 631 PAPTTPKEPAPTTPKGT-APTTLKEPAPTTPKKPAPKE----LAPTTTKGPTSTTSDKPA 685

Query: 482 PPQPHRRAETKARLPPPR-PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK 540
           P  P   A T  + P P  P++PA T  PE  PP   +  V        P+       E 
Sbjct: 686 PTTPKETAPTTPKEPAPTTPKKPAPT-TPETPPPTTSE--VSTPTTTKEPTTIHKSPDES 742

Query: 541 QREEGKVKQPQEEDWTPPDPGL 562
             E      P+  + +P +PG+
Sbjct: 743 TPELSAEPTPKALENSPKEPGV 764



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 30/108 (27%), Positives = 41/108 (37%), Gaps = 23/108 (21%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLP---------------PPRPQR 473
           P P TP+      PAP   K+P    +K+ P       P               P  P+ 
Sbjct: 270 PAPTTPK-----EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 324

Query: 474 PV-TKARRPPPQPHRRAETKARLPPPR-PQRPAETKVPEEIPPEVVQE 519
           P  T  + P P     A T  + P P  P++PA T  P+E  P   +E
Sbjct: 325 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT-TPKEPAPTTPKE 371



 Score = 33.9 bits (76), Expect = 0.47
 Identities = 32/129 (24%), Positives = 41/129 (31%), Gaps = 5/129 (3%)

Query: 434 PRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPV-TKARRPPPQPHRRAETK 492
           P L     P P   K+P     K  P   T    P  P+ P  T  +  P  P   A T 
Sbjct: 208 PALTTPKEPTPTTPKEPASTTPKE-PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT 266

Query: 493 ARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKVKQPQ 551
            + P P  P+ PA T   E  P           E    P+      P   +E       +
Sbjct: 267 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP--APTTPKKPAPTTPKEPAPTTPKE 324

Query: 552 EEDWTPPDP 560
               TP +P
Sbjct: 325 PTPTTPKEP 333



 Score = 33.1 bits (74), Expect = 0.79
 Identities = 34/133 (25%), Positives = 47/133 (35%), Gaps = 22/133 (16%)

Query: 429 PPPATPRLE-PRGP--PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQP 485
           P P TP+   P  P  PAP   K+P          A T     P+   P T     P  P
Sbjct: 530 PAPTTPKAAAPNTPKEPAPTTPKEP----------APTT----PKEPAPTTPKETAPTTP 575

Query: 486 HRRAETKARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 544
              A T  + P P  P++PA    P+E+ P   +E      +   P+      P   +E 
Sbjct: 576 KGTAPTTLKEPAPTTPKKPA----PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEP 631

Query: 545 GKVKQPQEEDWTP 557
                 +    TP
Sbjct: 632 APTTPKEPAPTTP 644



 Score = 31.6 bits (70), Expect = 2.3
 Identities = 27/91 (29%), Positives = 34/91 (37%), Gaps = 7/91 (7%)

Query: 425 PQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPP-PRPQRPVTKARRPPP 483
           P+ L P    +L P  P  P         P+   P+  T   P  P P  P   A   P 
Sbjct: 487 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT--PEEPTPTTPEEPAPTTPKAAAPNTPK 544

Query: 484 QPHRRAETKARLP-PPRPQRPAETKVPEEIP 513
           +P   A T  + P P  P+ PA T   E  P
Sbjct: 545 EP---APTTPKEPAPTTPKEPAPTTPKETAP 572



 Score = 29.6 bits (65), Expect = 8.8
 Identities = 28/114 (24%), Positives = 39/114 (34%), Gaps = 12/114 (10%)

Query: 455 SKAGPKAQTACLPP----PRPQRPVTKARRPPPQPHRRAETKARLPPPRPQRPAET---- 506
           +K  PKA+T    P    P+   P T        P     T  +  P  P+ PA T    
Sbjct: 195 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 254

Query: 507 --KVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKVKQPQEEDWTPP 558
               P+E  P   +E      +   P+   T EP     +     P+E   T P
Sbjct: 255 APTTPKEPAPTTTKEPAPTTPKEPAPT--TTKEPAPTTTKSAPTTPKEPAPTTP 306


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 37/137 (27%), Positives = 51/137 (37%), Gaps = 13/137 (9%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPP----PRPQRPVTKARRPPPQ 484
           P P TP+      PAP   K+P   P+     A T    P    P+   P T     P  
Sbjct: 475 PAPTTPK-----KPAPTTPKEPA--PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 527

Query: 485 PHRRAETKA-RLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQRE 543
           P +   T   +L P  P++PA T  PEE+ P   +E      E   P+      P   +E
Sbjct: 528 PKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 586

Query: 544 EGKVKQPQEEDWTPPDP 560
                  +    TP +P
Sbjct: 587 PAPTTPKEPAPTTPKEP 603



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 36/135 (26%), Positives = 49/135 (36%), Gaps = 10/135 (7%)

Query: 429 PPPATPRLEPRGP--PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPH 486
           P P T +  P  P  P+P   K+P   P+     A T     P+   P T     P  P 
Sbjct: 444 PAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTT----PKKPAPTTPKEPAPTTPK 497

Query: 487 RRAETKARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG 545
             A T  + P P  P+ PA T  P+E  P   ++      E L P+      P    E  
Sbjct: 498 EPAPTTTKKPAPTTPKEPAPT-TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA 556

Query: 546 KVKQPQEEDWTPPDP 560
                +    TP +P
Sbjct: 557 PTTPEEPTPTTPEEP 571



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 32/135 (23%), Positives = 44/135 (32%), Gaps = 11/135 (8%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPP----PRPQRPVTKARRPPPQ 484
           P P TP+      PAP   K+P   P+     A T    P    P+   P T  +  P  
Sbjct: 483 PAPTTPK-----EPAPTTPKEPA--PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 535

Query: 485 PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 544
           P + A T    P P          PEE  P   +E      +   P+      P   +E 
Sbjct: 536 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 595

Query: 545 GKVKQPQEEDWTPPD 559
                 +    TP +
Sbjct: 596 APTTPKEPAPTTPKE 610



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 32/99 (32%), Positives = 41/99 (41%), Gaps = 13/99 (13%)

Query: 429 PPPATPRLEPRGP--PAPEVVKQPVYL----PSKAGPKAQTACLPPPRPQRPVTKARRPP 482
           P P T +  P  P  PAP   K+P       P+   PK  T    P  P+ P    + P 
Sbjct: 327 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT----PTTPKEPAPTTKEPA 382

Query: 483 PQ-PHRRAETKARLPPPR-PQRPAETKVPEEIPPEVVQE 519
           P  P   A T  + P P  P+ PA T  P+E  P   +E
Sbjct: 383 PTTPKEPAPTAPKKPAPTTPKEPAPT-TPKEPAPTTTKE 420



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 35/133 (26%), Positives = 48/133 (36%), Gaps = 14/133 (10%)

Query: 429 PPPATPRLEPRGP--PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPH 486
           P P T +  P  P  PAP   K     P +  P       P    +   T  + P P   
Sbjct: 273 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 332

Query: 487 RRAETKARLPPPR-PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG 545
           + A T  + P P  P++PA T  P+E  P   +E          P+     EP    +E 
Sbjct: 333 KSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKE----------PTPTTPKEPAPTTKEP 381

Query: 546 KVKQPQEEDWTPP 558
               P+E   T P
Sbjct: 382 APTTPKEPAPTAP 394



 Score = 37.4 bits (85), Expect = 0.042
 Identities = 24/89 (26%), Positives = 31/89 (34%), Gaps = 5/89 (5%)

Query: 429 PPPATPRLEPRGP----PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQ 484
           P P TP+ EP       P P  +K     P +  P    +    P+   P T     P  
Sbjct: 257 PTPTTPK-EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 315

Query: 485 PHRRAETKARLPPPRPQRPAETKVPEEIP 513
           P   A T  + P P   + A T   E  P
Sbjct: 316 PKEPAPTTTKEPAPTTTKSAPTTPKEPAP 344



 Score = 37.0 bits (84), Expect = 0.055
 Identities = 29/133 (21%), Positives = 45/133 (33%), Gaps = 8/133 (6%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPV-YLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHR 487
           P P TP+      PAP   K+P    P +  P  +      P+   P    +  P  P  
Sbjct: 350 PAPTTPK-----EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE 404

Query: 488 RAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKV 547
            A T  + P P   +      P+E  P   +      +E    +  +     K+      
Sbjct: 405 PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 464

Query: 548 KQPQEEDWTPPDP 560
           K+P     TP +P
Sbjct: 465 KEPAPT--TPKEP 475



 Score = 36.6 bits (83), Expect = 0.072
 Identities = 33/136 (24%), Positives = 47/136 (34%), Gaps = 5/136 (3%)

Query: 429 PPPATPRLE-PRGP--PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPV-TKARRPPPQ 484
           P P TP+   P  P  PAP   K+P     K      T    P  P+ P  T  +  P  
Sbjct: 381 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 440

Query: 485 PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 544
               A T  +  P  P+ P+ T   +E  P   +E      +   P+      P   +E 
Sbjct: 441 TKEPAPTTTKSAPTTPKEPSPT-TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 499

Query: 545 GKVKQPQEEDWTPPDP 560
                 +    TP +P
Sbjct: 500 APTTTKKPAPTTPKEP 515



 Score = 36.6 bits (83), Expect = 0.072
 Identities = 33/134 (24%), Positives = 47/134 (35%), Gaps = 7/134 (5%)

Query: 429 PPPATPRLEPRGP----PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQ 484
           P P TP+ EP       P+P   K+P    +K+ P       P      P T     P  
Sbjct: 405 PAPTTPK-EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 463

Query: 485 PHRRAETKARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQRE 543
               A T  + P P  P++PA T  P+E  P   +E      +   P+      P   +E
Sbjct: 464 TKEPAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKE 522

Query: 544 EGKVKQPQEEDWTP 557
                  +    TP
Sbjct: 523 TAPTTPKKLTPTTP 536



 Score = 36.6 bits (83), Expect = 0.072
 Identities = 40/142 (28%), Positives = 56/142 (39%), Gaps = 16/142 (11%)

Query: 429 PPPATPR----LEPRGPPAPEVVKQPV-YLPSKAGPKAQTACLPPPRPQRPV--TKARRP 481
           P P TP+      P+G  AP  +K+P    P K  PK     L P   + P   T  +  
Sbjct: 672 PAPTTPKEPAPTTPKGT-APTTLKEPAPTTPKKPAPKE----LAPTTTKGPTSTTSDKPA 726

Query: 482 PPQPHRRAETKARLPPPR-PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK 540
           P  P   A T  + P P  P++PA T  PE  PP   +  V        P+       E 
Sbjct: 727 PTTPKETAPTTPKEPAPTTPKKPAPT-TPETPPPTTSE--VSTPTTTKEPTTIHKSPDES 783

Query: 541 QREEGKVKQPQEEDWTPPDPGL 562
             E      P+  + +P +PG+
Sbjct: 784 TPELSAEPTPKALENSPKEPGV 805



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 30/108 (27%), Positives = 41/108 (37%), Gaps = 23/108 (21%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLP---------------PPRPQR 473
           P P TP+      PAP   K+P    +K+ P       P               P  P+ 
Sbjct: 311 PAPTTPK-----EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 365

Query: 474 PV-TKARRPPPQPHRRAETKARLPPPR-PQRPAETKVPEEIPPEVVQE 519
           P  T  + P P     A T  + P P  P++PA T  P+E  P   +E
Sbjct: 366 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT-TPKEPAPTTPKE 412



 Score = 33.9 bits (76), Expect = 0.47
 Identities = 32/129 (24%), Positives = 41/129 (31%), Gaps = 5/129 (3%)

Query: 434 PRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPV-TKARRPPPQPHRRAETK 492
           P L     P P   K+P     K  P   T    P  P+ P  T  +  P  P   A T 
Sbjct: 249 PALTTPKEPTPTTPKEPASTTPKE-PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT 307

Query: 493 ARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKVKQPQ 551
            + P P  P+ PA T   E  P           E    P+      P   +E       +
Sbjct: 308 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP--APTTPKKPAPTTPKEPAPTTPKE 365

Query: 552 EEDWTPPDP 560
               TP +P
Sbjct: 366 PTPTTPKEP 374



 Score = 33.1 bits (74), Expect = 0.79
 Identities = 34/133 (25%), Positives = 47/133 (35%), Gaps = 22/133 (16%)

Query: 429 PPPATPRLE-PRGP--PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQP 485
           P P TP+   P  P  PAP   K+P          A T     P+   P T     P  P
Sbjct: 571 PAPTTPKAAAPNTPKEPAPTTPKEP----------APTT----PKEPAPTTPKETAPTTP 616

Query: 486 HRRAETKARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 544
              A T  + P P  P++PA    P+E+ P   +E      +   P+      P   +E 
Sbjct: 617 KGTAPTTLKEPAPTTPKKPA----PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEP 672

Query: 545 GKVKQPQEEDWTP 557
                 +    TP
Sbjct: 673 APTTPKEPAPTTP 685



 Score = 31.6 bits (70), Expect = 2.3
 Identities = 27/91 (29%), Positives = 34/91 (37%), Gaps = 7/91 (7%)

Query: 425 PQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPP-PRPQRPVTKARRPPP 483
           P+ L P    +L P  P  P         P+   P+  T   P  P P  P   A   P 
Sbjct: 528 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT--PEEPTPTTPEEPAPTTPKAAAPNTPK 585

Query: 484 QPHRRAETKARLP-PPRPQRPAETKVPEEIP 513
           +P   A T  + P P  P+ PA T   E  P
Sbjct: 586 EP---APTTPKEPAPTTPKEPAPTTPKETAP 613



 Score = 29.6 bits (65), Expect = 8.8
 Identities = 28/114 (24%), Positives = 39/114 (34%), Gaps = 12/114 (10%)

Query: 455 SKAGPKAQTACLPP----PRPQRPVTKARRPPPQPHRRAETKARLPPPRPQRPAET---- 506
           +K  PKA+T    P    P+   P T        P     T  +  P  P+ PA T    
Sbjct: 236 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 295

Query: 507 --KVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKVKQPQEEDWTPP 558
               P+E  P   +E      +   P+   T EP     +     P+E   T P
Sbjct: 296 APTTPKEPAPTTTKEPAPTTPKEPAPT--TTKEPAPTTTKSAPTTPKEPAPTTP 347


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 37/137 (27%), Positives = 51/137 (37%), Gaps = 13/137 (9%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPP----PRPQRPVTKARRPPPQ 484
           P P TP+      PAP   K+P   P+     A T    P    P+   P T     P  
Sbjct: 527 PAPTTPK-----KPAPTTPKEPA--PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 579

Query: 485 PHRRAETKA-RLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQRE 543
           P +   T   +L P  P++PA T  PEE+ P   +E      E   P+      P   +E
Sbjct: 580 PKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 638

Query: 544 EGKVKQPQEEDWTPPDP 560
                  +    TP +P
Sbjct: 639 PAPTTPKEPAPTTPKEP 655



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 36/135 (26%), Positives = 49/135 (36%), Gaps = 10/135 (7%)

Query: 429 PPPATPRLEPRGP--PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPH 486
           P P T +  P  P  P+P   K+P   P+     A T     P+   P T     P  P 
Sbjct: 496 PAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTT----PKKPAPTTPKEPAPTTPK 549

Query: 487 RRAETKARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG 545
             A T  + P P  P+ PA T  P+E  P   ++      E L P+      P    E  
Sbjct: 550 EPAPTTTKKPAPTTPKEPAPT-TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA 608

Query: 546 KVKQPQEEDWTPPDP 560
                +    TP +P
Sbjct: 609 PTTPEEPTPTTPEEP 623



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 32/135 (23%), Positives = 44/135 (32%), Gaps = 11/135 (8%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPP----PRPQRPVTKARRPPPQ 484
           P P TP+      PAP   K+P   P+     A T    P    P+   P T  +  P  
Sbjct: 535 PAPTTPK-----EPAPTTPKEPA--PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 587

Query: 485 PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 544
           P + A T    P P          PEE  P   +E      +   P+      P   +E 
Sbjct: 588 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 647

Query: 545 GKVKQPQEEDWTPPD 559
                 +    TP +
Sbjct: 648 APTTPKEPAPTTPKE 662



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 32/99 (32%), Positives = 41/99 (41%), Gaps = 13/99 (13%)

Query: 429 PPPATPRLEPRGP--PAPEVVKQPVYL----PSKAGPKAQTACLPPPRPQRPVTKARRPP 482
           P P T +  P  P  PAP   K+P       P+   PK  T    P  P+ P    + P 
Sbjct: 379 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT----PTTPKEPAPTTKEPA 434

Query: 483 PQ-PHRRAETKARLPPPR-PQRPAETKVPEEIPPEVVQE 519
           P  P   A T  + P P  P+ PA T  P+E  P   +E
Sbjct: 435 PTTPKEPAPTAPKKPAPTTPKEPAPT-TPKEPAPTTTKE 472



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 35/133 (26%), Positives = 48/133 (36%), Gaps = 14/133 (10%)

Query: 429 PPPATPRLEPRGP--PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPH 486
           P P T +  P  P  PAP   K     P +  P       P    +   T  + P P   
Sbjct: 325 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 384

Query: 487 RRAETKARLPPPR-PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG 545
           + A T  + P P  P++PA T  P+E  P   +E          P+     EP    +E 
Sbjct: 385 KSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKE----------PTPTTPKEPAPTTKEP 433

Query: 546 KVKQPQEEDWTPP 558
               P+E   T P
Sbjct: 434 APTTPKEPAPTAP 446



 Score = 37.4 bits (85), Expect = 0.042
 Identities = 24/89 (26%), Positives = 31/89 (34%), Gaps = 5/89 (5%)

Query: 429 PPPATPRLEPRGP----PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQ 484
           P P TP+ EP       P P  +K     P +  P    +    P+   P T     P  
Sbjct: 309 PTPTTPK-EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 367

Query: 485 PHRRAETKARLPPPRPQRPAETKVPEEIP 513
           P   A T  + P P   + A T   E  P
Sbjct: 368 PKEPAPTTTKEPAPTTTKSAPTTPKEPAP 396



 Score = 37.0 bits (84), Expect = 0.055
 Identities = 29/133 (21%), Positives = 45/133 (33%), Gaps = 8/133 (6%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPV-YLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHR 487
           P P TP+      PAP   K+P    P +  P  +      P+   P    +  P  P  
Sbjct: 402 PAPTTPK-----EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE 456

Query: 488 RAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKV 547
            A T  + P P   +      P+E  P   +      +E    +  +     K+      
Sbjct: 457 PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 516

Query: 548 KQPQEEDWTPPDP 560
           K+P     TP +P
Sbjct: 517 KEPAPT--TPKEP 527



 Score = 36.6 bits (83), Expect = 0.072
 Identities = 33/136 (24%), Positives = 47/136 (34%), Gaps = 5/136 (3%)

Query: 429 PPPATPRLE-PRGP--PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPV-TKARRPPPQ 484
           P P TP+   P  P  PAP   K+P     K      T    P  P+ P  T  +  P  
Sbjct: 433 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 492

Query: 485 PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 544
               A T  +  P  P+ P+ T   +E  P   +E      +   P+      P   +E 
Sbjct: 493 TKEPAPTTTKSAPTTPKEPSPT-TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 551

Query: 545 GKVKQPQEEDWTPPDP 560
                 +    TP +P
Sbjct: 552 APTTTKKPAPTTPKEP 567



 Score = 36.6 bits (83), Expect = 0.072
 Identities = 33/134 (24%), Positives = 47/134 (35%), Gaps = 7/134 (5%)

Query: 429 PPPATPRLEPRGP----PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQ 484
           P P TP+ EP       P+P   K+P    +K+ P       P      P T     P  
Sbjct: 457 PAPTTPK-EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 515

Query: 485 PHRRAETKARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQRE 543
               A T  + P P  P++PA T  P+E  P   +E      +   P+      P   +E
Sbjct: 516 TKEPAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKE 574

Query: 544 EGKVKQPQEEDWTP 557
                  +    TP
Sbjct: 575 TAPTTPKKLTPTTP 588



 Score = 36.6 bits (83), Expect = 0.072
 Identities = 40/142 (28%), Positives = 56/142 (39%), Gaps = 16/142 (11%)

Query: 429 PPPATPR----LEPRGPPAPEVVKQPV-YLPSKAGPKAQTACLPPPRPQRPV--TKARRP 481
           P P TP+      P+G  AP  +K+P    P K  PK     L P   + P   T  +  
Sbjct: 724 PAPTTPKEPAPTTPKGT-APTTLKEPAPTTPKKPAPKE----LAPTTTKGPTSTTSDKPA 778

Query: 482 PPQPHRRAETKARLPPPR-PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK 540
           P  P   A T  + P P  P++PA T  PE  PP   +  V        P+       E 
Sbjct: 779 PTTPKETAPTTPKEPAPTTPKKPAPT-TPETPPPTTSE--VSTPTTTKEPTTIHKSPDES 835

Query: 541 QREEGKVKQPQEEDWTPPDPGL 562
             E      P+  + +P +PG+
Sbjct: 836 TPELSAEPTPKALENSPKEPGV 857



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 30/108 (27%), Positives = 41/108 (37%), Gaps = 23/108 (21%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLP---------------PPRPQR 473
           P P TP+      PAP   K+P    +K+ P       P               P  P+ 
Sbjct: 363 PAPTTPK-----EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 417

Query: 474 PV-TKARRPPPQPHRRAETKARLPPPR-PQRPAETKVPEEIPPEVVQE 519
           P  T  + P P     A T  + P P  P++PA T  P+E  P   +E
Sbjct: 418 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT-TPKEPAPTTPKE 464



 Score = 33.9 bits (76), Expect = 0.47
 Identities = 32/129 (24%), Positives = 41/129 (31%), Gaps = 5/129 (3%)

Query: 434 PRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPV-TKARRPPPQPHRRAETK 492
           P L     P P   K+P     K  P   T    P  P+ P  T  +  P  P   A T 
Sbjct: 301 PALTTPKEPTPTTPKEPASTTPKE-PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT 359

Query: 493 ARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKVKQPQ 551
            + P P  P+ PA T   E  P           E    P+      P   +E       +
Sbjct: 360 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP--APTTPKKPAPTTPKEPAPTTPKE 417

Query: 552 EEDWTPPDP 560
               TP +P
Sbjct: 418 PTPTTPKEP 426



 Score = 33.1 bits (74), Expect = 0.79
 Identities = 34/133 (25%), Positives = 47/133 (35%), Gaps = 22/133 (16%)

Query: 429 PPPATPRLE-PRGP--PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQP 485
           P P TP+   P  P  PAP   K+P          A T     P+   P T     P  P
Sbjct: 623 PAPTTPKAAAPNTPKEPAPTTPKEP----------APTT----PKEPAPTTPKETAPTTP 668

Query: 486 HRRAETKARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 544
              A T  + P P  P++PA    P+E+ P   +E      +   P+      P   +E 
Sbjct: 669 KGTAPTTLKEPAPTTPKKPA----PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEP 724

Query: 545 GKVKQPQEEDWTP 557
                 +    TP
Sbjct: 725 APTTPKEPAPTTP 737



 Score = 31.6 bits (70), Expect = 2.3
 Identities = 27/91 (29%), Positives = 34/91 (37%), Gaps = 7/91 (7%)

Query: 425 PQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPP-PRPQRPVTKARRPPP 483
           P+ L P    +L P  P  P         P+   P+  T   P  P P  P   A   P 
Sbjct: 580 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT--PEEPTPTTPEEPAPTTPKAAAPNTPK 637

Query: 484 QPHRRAETKARLP-PPRPQRPAETKVPEEIP 513
           +P   A T  + P P  P+ PA T   E  P
Sbjct: 638 EP---APTTPKEPAPTTPKEPAPTTPKETAP 665



 Score = 29.6 bits (65), Expect = 8.8
 Identities = 28/114 (24%), Positives = 39/114 (34%), Gaps = 12/114 (10%)

Query: 455 SKAGPKAQTACLPP----PRPQRPVTKARRPPPQPHRRAETKARLPPPRPQRPAET---- 506
           +K  PKA+T    P    P+   P T        P     T  +  P  P+ PA T    
Sbjct: 288 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 347

Query: 507 --KVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKVKQPQEEDWTPP 558
               P+E  P   +E      +   P+   T EP     +     P+E   T P
Sbjct: 348 APTTPKEPAPTTTKEPAPTTPKEPAPT--TTKEPAPTTTKSAPTTPKEPAPTTP 399


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 37/137 (27%), Positives = 51/137 (37%), Gaps = 13/137 (9%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPP----PRPQRPVTKARRPPPQ 484
           P P TP+      PAP   K+P   P+     A T    P    P+   P T     P  
Sbjct: 568 PAPTTPK-----KPAPTTPKEPA--PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 620

Query: 485 PHRRAETKA-RLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQRE 543
           P +   T   +L P  P++PA T  PEE+ P   +E      E   P+      P   +E
Sbjct: 621 PKKLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 679

Query: 544 EGKVKQPQEEDWTPPDP 560
                  +    TP +P
Sbjct: 680 PAPTTPKEPAPTTPKEP 696



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 36/135 (26%), Positives = 49/135 (36%), Gaps = 10/135 (7%)

Query: 429 PPPATPRLEPRGP--PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPH 486
           P P T +  P  P  P+P   K+P   P+     A T     P+   P T     P  P 
Sbjct: 537 PAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTT----PKKPAPTTPKEPAPTTPK 590

Query: 487 RRAETKARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG 545
             A T  + P P  P+ PA T  P+E  P   ++      E L P+      P    E  
Sbjct: 591 EPAPTTTKKPAPTTPKEPAPT-TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA 649

Query: 546 KVKQPQEEDWTPPDP 560
                +    TP +P
Sbjct: 650 PTTPEEPTPTTPEEP 664



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 32/135 (23%), Positives = 44/135 (32%), Gaps = 11/135 (8%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPP----PRPQRPVTKARRPPPQ 484
           P P TP+      PAP   K+P   P+     A T    P    P+   P T  +  P  
Sbjct: 576 PAPTTPK-----EPAPTTPKEPA--PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 628

Query: 485 PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 544
           P + A T    P P          PEE  P   +E      +   P+      P   +E 
Sbjct: 629 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 688

Query: 545 GKVKQPQEEDWTPPD 559
                 +    TP +
Sbjct: 689 APTTPKEPAPTTPKE 703



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 32/99 (32%), Positives = 41/99 (41%), Gaps = 13/99 (13%)

Query: 429 PPPATPRLEPRGP--PAPEVVKQPVYL----PSKAGPKAQTACLPPPRPQRPVTKARRPP 482
           P P T +  P  P  PAP   K+P       P+   PK  T    P  P+ P    + P 
Sbjct: 420 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT----PTTPKEPAPTTKEPA 475

Query: 483 PQ-PHRRAETKARLPPPR-PQRPAETKVPEEIPPEVVQE 519
           P  P   A T  + P P  P+ PA T  P+E  P   +E
Sbjct: 476 PTTPKEPAPTAPKKPAPTTPKEPAPT-TPKEPAPTTTKE 513



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 35/133 (26%), Positives = 48/133 (36%), Gaps = 14/133 (10%)

Query: 429 PPPATPRLEPRGP--PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPH 486
           P P T +  P  P  PAP   K     P +  P       P    +   T  + P P   
Sbjct: 366 PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT 425

Query: 487 RRAETKARLPPPR-PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEG 545
           + A T  + P P  P++PA T  P+E  P   +E          P+     EP    +E 
Sbjct: 426 KSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKE----------PTPTTPKEPAPTTKEP 474

Query: 546 KVKQPQEEDWTPP 558
               P+E   T P
Sbjct: 475 APTTPKEPAPTAP 487



 Score = 37.4 bits (85), Expect = 0.042
 Identities = 24/89 (26%), Positives = 31/89 (34%), Gaps = 5/89 (5%)

Query: 429 PPPATPRLEPRGP----PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQ 484
           P P TP+ EP       P P  +K     P +  P    +    P+   P T     P  
Sbjct: 350 PTPTTPK-EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 408

Query: 485 PHRRAETKARLPPPRPQRPAETKVPEEIP 513
           P   A T  + P P   + A T   E  P
Sbjct: 409 PKEPAPTTTKEPAPTTTKSAPTTPKEPAP 437



 Score = 37.0 bits (84), Expect = 0.055
 Identities = 29/133 (21%), Positives = 45/133 (33%), Gaps = 8/133 (6%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPV-YLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHR 487
           P P TP+      PAP   K+P    P +  P  +      P+   P    +  P  P  
Sbjct: 443 PAPTTPK-----EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE 497

Query: 488 RAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKV 547
            A T  + P P   +      P+E  P   +      +E    +  +     K+      
Sbjct: 498 PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 557

Query: 548 KQPQEEDWTPPDP 560
           K+P     TP +P
Sbjct: 558 KEPAPT--TPKEP 568



 Score = 36.6 bits (83), Expect = 0.072
 Identities = 33/136 (24%), Positives = 47/136 (34%), Gaps = 5/136 (3%)

Query: 429 PPPATPRLE-PRGP--PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPV-TKARRPPPQ 484
           P P TP+   P  P  PAP   K+P     K      T    P  P+ P  T  +  P  
Sbjct: 474 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTT 533

Query: 485 PHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 544
               A T  +  P  P+ P+ T   +E  P   +E      +   P+      P   +E 
Sbjct: 534 TKEPAPTTTKSAPTTPKEPSPT-TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 592

Query: 545 GKVKQPQEEDWTPPDP 560
                 +    TP +P
Sbjct: 593 APTTTKKPAPTTPKEP 608



 Score = 36.6 bits (83), Expect = 0.072
 Identities = 33/134 (24%), Positives = 47/134 (35%), Gaps = 7/134 (5%)

Query: 429 PPPATPRLEPRGP----PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQ 484
           P P TP+ EP       P+P   K+P    +K+ P       P      P T     P  
Sbjct: 498 PAPTTPK-EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 556

Query: 485 PHRRAETKARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQRE 543
               A T  + P P  P++PA T  P+E  P   +E      +   P+      P   +E
Sbjct: 557 TKEPAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKE 615

Query: 544 EGKVKQPQEEDWTP 557
                  +    TP
Sbjct: 616 TAPTTPKKLTPTTP 629



 Score = 36.6 bits (83), Expect = 0.072
 Identities = 40/142 (28%), Positives = 56/142 (39%), Gaps = 16/142 (11%)

Query: 429 PPPATPR----LEPRGPPAPEVVKQPV-YLPSKAGPKAQTACLPPPRPQRPV--TKARRP 481
           P P TP+      P+G  AP  +K+P    P K  PK     L P   + P   T  +  
Sbjct: 765 PAPTTPKEPAPTTPKGT-APTTLKEPAPTTPKKPAPKE----LAPTTTKGPTSTTSDKPA 819

Query: 482 PPQPHRRAETKARLPPPR-PQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEK 540
           P  P   A T  + P P  P++PA T  PE  PP   +  V        P+       E 
Sbjct: 820 PTTPKETAPTTPKEPAPTTPKKPAPT-TPETPPPTTSE--VSTPTTTKEPTTIHKSPDES 876

Query: 541 QREEGKVKQPQEEDWTPPDPGL 562
             E      P+  + +P +PG+
Sbjct: 877 TPELSAEPTPKALENSPKEPGV 898



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 30/108 (27%), Positives = 41/108 (37%), Gaps = 23/108 (21%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLP---------------PPRPQR 473
           P P TP+      PAP   K+P    +K+ P       P               P  P+ 
Sbjct: 404 PAPTTPK-----EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 458

Query: 474 PV-TKARRPPPQPHRRAETKARLPPPR-PQRPAETKVPEEIPPEVVQE 519
           P  T  + P P     A T  + P P  P++PA T  P+E  P   +E
Sbjct: 459 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT-TPKEPAPTTPKE 505



 Score = 33.9 bits (76), Expect = 0.47
 Identities = 32/129 (24%), Positives = 41/129 (31%), Gaps = 5/129 (3%)

Query: 434 PRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPV-TKARRPPPQPHRRAETK 492
           P L     P P   K+P     K  P   T    P  P+ P  T  +  P  P   A T 
Sbjct: 342 PALTTPKEPTPTTPKEPASTTPKE-PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT 400

Query: 493 ARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKVKQPQ 551
            + P P  P+ PA T   E  P           E    P+      P   +E       +
Sbjct: 401 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP--APTTPKKPAPTTPKEPAPTTPKE 458

Query: 552 EEDWTPPDP 560
               TP +P
Sbjct: 459 PTPTTPKEP 467



 Score = 33.1 bits (74), Expect = 0.79
 Identities = 34/133 (25%), Positives = 47/133 (35%), Gaps = 22/133 (16%)

Query: 429 PPPATPRLE-PRGP--PAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQP 485
           P P TP+   P  P  PAP   K+P          A T     P+   P T     P  P
Sbjct: 664 PAPTTPKAAAPNTPKEPAPTTPKEP----------APTT----PKEPAPTTPKETAPTTP 709

Query: 486 HRRAETKARLP-PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREE 544
              A T  + P P  P++PA    P+E+ P   +E      +   P+      P   +E 
Sbjct: 710 KGTAPTTLKEPAPTTPKKPA----PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEP 765

Query: 545 GKVKQPQEEDWTP 557
                 +    TP
Sbjct: 766 APTTPKEPAPTTP 778



 Score = 31.6 bits (70), Expect = 2.3
 Identities = 27/91 (29%), Positives = 34/91 (37%), Gaps = 7/91 (7%)

Query: 425 PQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPP-PRPQRPVTKARRPPP 483
           P+ L P    +L P  P  P         P+   P+  T   P  P P  P   A   P 
Sbjct: 621 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT--PEEPTPTTPEEPAPTTPKAAAPNTPK 678

Query: 484 QPHRRAETKARLP-PPRPQRPAETKVPEEIP 513
           +P   A T  + P P  P+ PA T   E  P
Sbjct: 679 EP---APTTPKEPAPTTPKEPAPTTPKETAP 706



 Score = 29.6 bits (65), Expect = 8.8
 Identities = 28/114 (24%), Positives = 39/114 (34%), Gaps = 12/114 (10%)

Query: 455 SKAGPKAQTACLPP----PRPQRPVTKARRPPPQPHRRAETKARLPPPRPQRPAET---- 506
           +K  PKA+T    P    P+   P T        P     T  +  P  P+ PA T    
Sbjct: 329 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 388

Query: 507 --KVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKVKQPQEEDWTPP 558
               P+E  P   +E      +   P+   T EP     +     P+E   T P
Sbjct: 389 APTTPKEPAPTTTKEPAPTTPKEPAPT--TTKEPAPTTTKSAPTTPKEPAPTTP 440


>gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo
           sapiens]
          Length = 1038

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 83/358 (23%), Positives = 122/358 (34%), Gaps = 74/358 (20%)

Query: 131 VLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSTFPSTPLVTEQ 190
           ++G GV A P    + +  +P     P P    L +    P GG                
Sbjct: 654 LVGAGVPAGPSQGQTNYAFVPEQARPPPPLEDNLFLP---PQGG---------------- 694

Query: 191 DGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGG---VVCPPPL 247
            G  PS A  + +F          +A Q + +   QAP    AP    GG      PP +
Sbjct: 695 -GKPPSSAQTAEIF----------QALQQECMRQLQAPAGSPAPSPSPGGDDKPQVPPRV 743

Query: 248 LLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHG 307
            +   P  P +        +     W    P P  PP      P+  QG+  P P    G
Sbjct: 744 PIPPRPTRPHVQLSPAPPGEEETSQW----PGPASPPRVPPREPLSPQGSRTPSPLVPPG 799

Query: 308 ESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSL 367
            S L       PP  S +P       + +      A   + Q+P   A  C ++P++R  
Sbjct: 800 SSPL-------PPRLSSSPGKTMPTTQSFASDPKYATPQVIQAPGPRAGPC-ILPIVRDG 851

Query: 368 ARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQC 427
            +   T               +    +R  + E  ++FL     E    ++   +  P  
Sbjct: 852 KKVSST--------------HYYLLPERPSYLERYQRFL----REAQSPEEPTPLPVPLL 893

Query: 428 LPPPATPRLEPRGPPAPEVVKQPVYLPSKA-GPKAQTA---CLPPPRPQRPVTKARRP 481
           LPPP+TP      P AP    +P  +P  A  PKA  +     P  RP  P   AR P
Sbjct: 894 LPPPSTP-----APAAPTATVRP--MPQAALDPKANFSTNNSNPGARPPPPRATARLP 944



 Score = 34.7 bits (78), Expect = 0.27
 Identities = 24/85 (28%), Positives = 33/85 (38%), Gaps = 16/85 (18%)

Query: 438 PRGPPAPEVVKQPVYLPSKAG---PKAQTACLPPPRPQRPVTKARRPPPQPHRRAE---- 490
           P G PAP         PS  G   P+       PPRP RP  +    PP     ++    
Sbjct: 721 PAGSPAPS--------PSPGGDDKPQVPPRVPIPPRPTRPHVQLSPAPPGEEETSQWPGP 772

Query: 491 -TKARLPPPRPQRPAETKVPEEIPP 514
            +  R+PP  P  P  ++ P  + P
Sbjct: 773 ASPPRVPPREPLSPQGSRTPSPLVP 797



 Score = 30.0 bits (66), Expect = 6.7
 Identities = 18/57 (31%), Positives = 23/57 (40%), Gaps = 2/57 (3%)

Query: 431 PATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVT--KARRPPPQP 485
           P  P L P  P   ++      L  +  P++ T  LP P    PV    AR  PP P
Sbjct: 577 PVVPALRPCAPSLAQLAMDACSLLDETPPQSPTRALPRPLHPTPVVDWDARPLPPPP 633


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 39/123 (31%), Positives = 50/123 (40%), Gaps = 12/123 (9%)

Query: 397 IFYEMAEKFLEFEA-EEEMQIQKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPS 455
           + Y+  EK    EA + E++ Q        +  PPP  P     GPP P    +    P 
Sbjct: 254 VIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGA--PP 311

Query: 456 KAGPKAQTACLPPPRPQRPVTKARRPPPQPHRRAETKARLPPPRPQRPAET-KVPEEIPP 514
               +A TA  PPP P RP      PPP P+R        PPP P  P+     P   PP
Sbjct: 312 PPPSRAPTAAPPPPPPSRPSVAV--PPPPPNR------MYPPPPPALPSSAPSGPPPPPP 363

Query: 515 EVV 517
            V+
Sbjct: 364 SVL 366



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 27/86 (31%), Positives = 32/86 (37%), Gaps = 7/86 (8%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHRR 488
           PPP  P    RG P P   + P   P    P   +  +PPP P R       PPP P   
Sbjct: 299 PPP--PPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNR-----MYPPPPPALP 351

Query: 489 AETKARLPPPRPQRPAETKVPEEIPP 514
           +   +  PPP P       V    PP
Sbjct: 352 SSAPSGPPPPPPSVLGVGPVAPPPPP 377



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 27/89 (30%), Positives = 32/89 (35%), Gaps = 6/89 (6%)

Query: 429 PPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHR- 487
           PPP   R     PP P   +  V +P    P       PPP P  P +    PPP P   
Sbjct: 310 PPPPPSRAPTAAPPPPPPSRPSVAVP----PPPPNRMYPPPPPALPSSAPSGPPPPPPSV 365

Query: 488 -RAETKARLPPPRPQRPAETKVPEEIPPE 515
                 A  PPP P  P     P  +P +
Sbjct: 366 LGVGPVAPPPPPPPPPPPGPPPPPGLPSD 394



 Score = 35.0 bits (79), Expect = 0.21
 Identities = 18/56 (32%), Positives = 25/56 (44%)

Query: 264 GGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGPWPQGAHGESSLASSQAKAP 319
           GG +A +    +  P PPPP      PP     N+GP P  A G  +     ++AP
Sbjct: 263 GGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAP 318



 Score = 31.2 bits (69), Expect = 3.0
 Identities = 33/137 (24%), Positives = 40/137 (29%), Gaps = 26/137 (18%)

Query: 155 PAPGPAHGPLLVTAGAPPGGPLVLSTFPSTPLVTEQDGCSPSGAGASNVFVQMRTEVGPV 214
           P P P+ G      G PP  P   ++ P  P    +    P  + A            P 
Sbjct: 278 PPPPPSRG------GPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPS 331

Query: 215 KAAQAQTLVLTQAPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWS 274
            A           P     P +   G   PPP +L   PV P                  
Sbjct: 332 VAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPP----------------- 374

Query: 275 QGLPLPPPPPPAAQLPP 291
              P PPPPPP    PP
Sbjct: 375 ---PPPPPPPPPGPPPP 388



 Score = 31.2 bits (69), Expect = 3.0
 Identities = 19/48 (39%), Positives = 22/48 (45%), Gaps = 4/48 (8%)

Query: 244 PPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPP 291
           PPP L ++AP  P      V G     G  +   P PPPPPP    PP
Sbjct: 346 PPPALPSSAPSGPPPPPPSVLGV----GPVAPPPPPPPPPPPGPPPPP 389


>gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens]
          Length = 669

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 39/152 (25%), Positives = 60/152 (39%), Gaps = 30/152 (19%)

Query: 425 PQCLPPPATPRLEPRGPPAPE---VVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRP 481
           P+  P P    L  +  P PE     + P++ P  + PK  ++  P    Q P++   + 
Sbjct: 225 PKKPPQPQVGGLPKKSVPQPEFSEAAQTPLWKPQSSEPKRDSSAFPKKASQPPLSDFPKK 284

Query: 482 PPQPHRRAETKARLPP-----PRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLG--- 533
           PPQP     T+    P     P+  RPAE K   + PP+              P LG   
Sbjct: 285 PPQPELGDLTRTSSEPEVSVLPKRPRPAEFKALSKKPPQ--------------PELGGLP 330

Query: 534 -ATGEPEKQREEGKVKQPQE----EDWTPPDP 560
             + EPE      K+ QP+       ++ P+P
Sbjct: 331 RTSSEPEFNSLPRKLLQPERRGPPRKFSQPEP 362



 Score = 37.0 bits (84), Expect = 0.055
 Identities = 40/141 (28%), Positives = 58/141 (41%), Gaps = 29/141 (20%)

Query: 438 PRGPPAPEVVKQPVYL-------PSKAG-PKAQTACLPPPRPQRPVTKARRPPPQPHRRA 489
           P+ PP PE  K   +        P KA  P+     L PP P+  VT   + PP P    
Sbjct: 33  PKKPPKPEFGKLKKFSQPELSEHPKKAPLPEFGAVSLKPPPPE--VTDLPKKPPPP---- 86

Query: 490 ETKARLPPPRPQRPAETKVPEEIPPEVVQ---------EYVDIMEELLGPSLGATGEPEK 540
             +    P +P  P  T +P++ PP  V          E  D+ ++   P LGAT  P K
Sbjct: 87  --EVTDLPKKPPPPEVTDLPKKPPPPEVTDLPKKPSKLELSDLSKKF--PQLGATPFPRK 142

Query: 541 QREEGKVKQPQEEDWTPPDPG 561
             +    + P +   + P+PG
Sbjct: 143 PLQPEVGEAPLKA--SLPEPG 161



 Score = 36.6 bits (83), Expect = 0.072
 Identities = 55/211 (26%), Positives = 74/211 (35%), Gaps = 37/211 (17%)

Query: 429 PPPATPRLEPRGPPAPEVVKQP--------VYLPSKAGP-----------KAQTACLPPP 469
           PPP    L P+ PP PEV   P          LP K  P           K + + L   
Sbjct: 72  PPPEVTDL-PKKPPPPEVTDLPKKPPPPEVTDLPKKPPPPEVTDLPKKPSKLELSDLSKK 130

Query: 470 RPQRPVTKARRPPPQPH-RRAETKARLPPP-----RPQRPAETKVPEEIPPEVVQEYV-- 521
            PQ   T   R P QP    A  KA LP P     +P +P E   P   P E        
Sbjct: 131 FPQLGATPFPRKPLQPEVGEAPLKASLPEPGAPARKPLQPDELSHPARPPSEPKSGAFPR 190

Query: 522 DIMEELLGPSLGATGEPEKQREEGKVKQPQEEDW--TPPDPGLLSYIDKLCSQKDFVTKV 579
            + +   G +   + +PE      K  QP+   +   PP P +     K   Q +F    
Sbjct: 191 KLWQPEAGEATPRSPQPELSTFPKKPAQPEFNVYPKKPPQPQVGGLPKKSVPQPEFSEAA 250

Query: 580 EAVI-HPQFLEELLSPDPQMDFLALSQDLEQ 609
           +  +  PQ      S +P+ D  A  +   Q
Sbjct: 251 QTPLWKPQ------SSEPKRDSSAFPKKASQ 275



 Score = 33.1 bits (74), Expect = 0.79
 Identities = 51/192 (26%), Positives = 71/192 (36%), Gaps = 39/192 (20%)

Query: 420 QWMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAG-PKAQTACLPPPRPQRPVTKA 478
           +W  G       A P L P  PP     ++P+   S  G P A+     PP P  PV   
Sbjct: 417 RWRSGGLVHSGGARPGLRPSHPPR----RRPLPPASSLGHPPAK-----PPLPPGPVDMQ 467

Query: 479 --RRPPPQPH--RRAETKARLPPPRPQRPAETKVPEEIP-PEVVQEYVDIMEELLGPSLG 533
             RRP       RR  + A L         + + PE+IP P+ + E  D +E     S  
Sbjct: 468 SFRRPSAASIDLRRTRSAAGLH-------FQDRQPEDIPVPDEIYELYDDVEPRDDSSPS 520

Query: 534 ATGEPEKQREEG------------KVKQPQEEDWTPPDPGLLSYIDKLCS-----QKDFV 576
             G  E    +             K K PQ +   P DP LL  + K        +K F 
Sbjct: 521 PKGRDEAPSVQQAARRPPQDPALRKEKDPQPQQLPPMDPKLLKQLRKAEKAEREFRKKFK 580

Query: 577 TKVEAVIHPQFL 588
            + E V+H + +
Sbjct: 581 FEGEIVVHTKMM 592


>gi|226051634 zinc finger protein 414 isoform 1 [Homo sapiens]
          Length = 390

 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 63/242 (26%), Positives = 86/242 (35%), Gaps = 32/242 (13%)

Query: 282 PPPPAAQLPPIVSQGNAGPWPQGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKP 341
           P P  A  PP+  +G AG   QG    SS A    +  P  S    S+       +  +P
Sbjct: 45  PGPEQAATPPVWERGGAGGMQQG----SSPAPDSCQPGPGPSPGLTSIVSGTS--EDLRP 98

Query: 342 LARRHLP--QSPDTEALSCFLIPVLRSLARR-----KPTMTLEEGLWR-----------A 383
             RR  P  Q P +    C   P +R LA+       PT +LE  L+R           +
Sbjct: 99  PRRRPPPGKQIPCSSPGCCLSFPSVRDLAQHLRTHCPPTQSLEGKLFRCSALSCTETFPS 158

Query: 384 MREWQHTS--NFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPRGP 441
           M+E    S  ++    +++     L F     +        +  Q   PP  P L+ R P
Sbjct: 159 MQELVAHSKLHYKPNRYFKCENCLLRFRTHRSLFKHLHVCAEHAQSPAPPPPPALD-REP 217

Query: 442 PAPEVVKQ--PVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPP---QPHRRAETKARLP 496
           PAPE   +  P   P    P  +    P P P  P      P P    P R     A  P
Sbjct: 218 PAPERPPEVDPASAPGLPFPLLEPFTTPAPAPTGPFLPYLNPAPFGLSPPRLRPFLAAAP 277

Query: 497 PP 498
            P
Sbjct: 278 GP 279


>gi|226051591 zinc finger protein 414 isoform 2 [Homo sapiens]
          Length = 312

 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 63/242 (26%), Positives = 86/242 (35%), Gaps = 32/242 (13%)

Query: 282 PPPPAAQLPPIVSQGNAGPWPQGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKP 341
           P P  A  PP+  +G AG   QG    SS A    +  P  S    S+       +  +P
Sbjct: 45  PGPEQAATPPVWERGGAGGMQQG----SSPAPDSCQPGPGPSPGLTSIVSGTS--EDLRP 98

Query: 342 LARRHLP--QSPDTEALSCFLIPVLRSLARR-----KPTMTLEEGLWR-----------A 383
             RR  P  Q P +    C   P +R LA+       PT +LE  L+R           +
Sbjct: 99  PRRRPPPGKQIPCSSPGCCLSFPSVRDLAQHLRTHCPPTQSLEGKLFRCSALSCTETFPS 158

Query: 384 MREWQHTS--NFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPRGP 441
           M+E    S  ++    +++     L F     +        +  Q   PP  P L+ R P
Sbjct: 159 MQELVAHSKLHYKPNRYFKCENCLLRFRTHRSLFKHLHVCAEHAQSPAPPPPPALD-REP 217

Query: 442 PAPEVVKQ--PVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPP---QPHRRAETKARLP 496
           PAPE   +  P   P    P  +    P P P  P      P P    P R     A  P
Sbjct: 218 PAPERPPEVDPASAPGLPFPLLEPFTTPAPAPTGPFLPYLNPAPFGLSPPRLRPFLAAAP 277

Query: 497 PP 498
            P
Sbjct: 278 GP 279


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 58/194 (29%), Positives = 77/194 (39%), Gaps = 36/194 (18%)

Query: 117 SAQPEGMASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPL 176
           SA P G+   GA P+  PG   +P         LP     PGP  GP L  A +P   P 
Sbjct: 314 SASPPGL---GAQPL--PGHLPSPHAMGQGMGGLP-----PGPEKGPTL--APSPHSLPP 361

Query: 177 VLSTFPSTPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGA 236
             S+ P+ P+       S S A AS+      +   P  A+QA    L   P  +  P +
Sbjct: 362 ASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQA----LPSYPHSFPPPTS 417

Query: 237 LCGGVVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQG 296
           L   V   PP         P + +Q V         WSQG P   PPPP  +L    S  
Sbjct: 418 L--SVSNQPPKYTQ-----PSLPSQAV---------WSQGPP---PPPPYGRL-LANSNA 457

Query: 297 NAGPWPQGAHGESS 310
           + GP+P     +S+
Sbjct: 458 HPGPFPPSTGAQST 471



 Score = 36.6 bits (83), Expect = 0.072
 Identities = 34/109 (31%), Positives = 39/109 (35%), Gaps = 24/109 (22%)

Query: 429 PPPATP----RLEPRGPPAPEVVKQPV---YLPSKAGPKAQ----TACLPPPRPQRPVTK 477
           PPP TP         G P  +    PV    LPS A P A     T  LPPP   RP+  
Sbjct: 254 PPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPS-APPPANFPHVTPNLPPPPALRPLNN 312

Query: 478 ARRPPP------------QPHRRAETKARLPPPRPQRPAETKVPEEIPP 514
           A   PP             PH   +    LPP   + P     P  +PP
Sbjct: 313 ASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPP 361



 Score = 30.8 bits (68), Expect = 3.9
 Identities = 81/334 (24%), Positives = 119/334 (35%), Gaps = 35/334 (10%)

Query: 133 GPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAP-PGGPLVLSTFPSTPLVTEQD 191
           GP V+++  +S S      +    P P+ GP     GAP P  P+   T  S  L T   
Sbjct: 565 GPPVSSSSNSSSSTSQG-SYPCSHPSPSQGP----QGAPYPFPPVPTVTTSSATLSTVIA 619

Query: 192 GCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGGVVCPPPLLLAA 251
             + S AG            G  K A +     T  P  ++           PP     +
Sbjct: 620 TVASSPAGYKTASPPGPPPYG--KRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTS 677

Query: 252 APVVPVM---AAQVVGGTQACEGGWSQGLPLPPPPP--PAAQLPPIVSQGNAGPWPQGAH 306
            P  P      +  VG       G S GLP  PPPP  PA+  P   +Q    P  +   
Sbjct: 678 PPAGPGTFKPGSPTVGPGPLPPAGPS-GLPSLPPPPAAPASGPPLSATQIKQEPAEEYET 736

Query: 307 GESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLAR--RHLPQSPDTEALS-CFLIPV 363
            ES +  +++ +PP    +  S         H    AR  +HL +  ++ A S  + +P+
Sbjct: 737 PESPVPPARSPSPPPKVVDVPS---------HASQSARFNKHLDRGFNSCARSDLYFVPL 787

Query: 364 LRSLARRKPTMTLE----EGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKS 419
             S   +K    +E    E   RA  E +     +R       E+  E E E E  ++ +
Sbjct: 788 EGSKLAKKRADLVEKVRREAEQRAREEKERERERER-----EKEREREKERELERSVKLA 842

Query: 420 QWMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYL 453
           Q  + P   P        P   P   V   P YL
Sbjct: 843 QEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYL 876


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 58/194 (29%), Positives = 77/194 (39%), Gaps = 36/194 (18%)

Query: 117 SAQPEGMASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPL 176
           SA P G+   GA P+  PG   +P         LP     PGP  GP L  A +P   P 
Sbjct: 314 SASPPGL---GAQPL--PGHLPSPHAMGQGMGGLP-----PGPEKGPTL--APSPHSLPP 361

Query: 177 VLSTFPSTPLVTEQDGCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGA 236
             S+ P+ P+       S S A AS+      +   P  A+QA    L   P  +  P +
Sbjct: 362 ASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQA----LPSYPHSFPPPTS 417

Query: 237 LCGGVVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQG 296
           L   V   PP         P + +Q V         WSQG P   PPPP  +L    S  
Sbjct: 418 L--SVSNQPPKYTQ-----PSLPSQAV---------WSQGPP---PPPPYGRL-LANSNA 457

Query: 297 NAGPWPQGAHGESS 310
           + GP+P     +S+
Sbjct: 458 HPGPFPPSTGAQST 471



 Score = 36.6 bits (83), Expect = 0.072
 Identities = 34/109 (31%), Positives = 39/109 (35%), Gaps = 24/109 (22%)

Query: 429 PPPATP----RLEPRGPPAPEVVKQPV---YLPSKAGPKAQ----TACLPPPRPQRPVTK 477
           PPP TP         G P  +    PV    LPS A P A     T  LPPP   RP+  
Sbjct: 254 PPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPS-APPPANFPHVTPNLPPPPALRPLNN 312

Query: 478 ARRPPP------------QPHRRAETKARLPPPRPQRPAETKVPEEIPP 514
           A   PP             PH   +    LPP   + P     P  +PP
Sbjct: 313 ASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPP 361



 Score = 30.8 bits (68), Expect = 3.9
 Identities = 81/334 (24%), Positives = 119/334 (35%), Gaps = 35/334 (10%)

Query: 133 GPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAP-PGGPLVLSTFPSTPLVTEQD 191
           GP V+++  +S S      +    P P+ GP     GAP P  P+   T  S  L T   
Sbjct: 565 GPPVSSSSNSSSSTSQG-SYPCSHPSPSQGP----QGAPYPFPPVPTVTTSSATLSTVIA 619

Query: 192 GCSPSGAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGGVVCPPPLLLAA 251
             + S AG            G  K A +     T  P  ++           PP     +
Sbjct: 620 TVASSPAGYKTASPPGPPPYG--KRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTS 677

Query: 252 APVVPVM---AAQVVGGTQACEGGWSQGLPLPPPPP--PAAQLPPIVSQGNAGPWPQGAH 306
            P  P      +  VG       G S GLP  PPPP  PA+  P   +Q    P  +   
Sbjct: 678 PPAGPGTFKPGSPTVGPGPLPPAGPS-GLPSLPPPPAAPASGPPLSATQIKQEPAEEYET 736

Query: 307 GESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLAR--RHLPQSPDTEALS-CFLIPV 363
            ES +  +++ +PP    +  S         H    AR  +HL +  ++ A S  + +P+
Sbjct: 737 PESPVPPARSPSPPPKVVDVPS---------HASQSARFNKHLDRGFNSCARSDLYFVPL 787

Query: 364 LRSLARRKPTMTLE----EGLWRAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKS 419
             S   +K    +E    E   RA  E +     +R       E+  E E E E  ++ +
Sbjct: 788 EGSKLAKKRADLVEKVRREAEQRAREEKERERERER-----EKEREREKERELERSVKLA 842

Query: 420 QWMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYL 453
           Q  + P   P        P   P   V   P YL
Sbjct: 843 QEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYL 876


>gi|18959210 WIRE protein [Homo sapiens]
          Length = 440

 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 43/162 (26%), Positives = 52/162 (32%), Gaps = 20/162 (12%)

Query: 419 SQWMKGPQCLPPPATPRLEPRGPPAPEVV---KQPVYLPSKAGPKAQTACLPPPRPQRPV 475
           S  MK     PPP  P      PP P  +   K P Y   K  P      L P R   P 
Sbjct: 167 STGMKHSSSAPPPPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHPGREGPPA 226

Query: 476 TKARRPPPQPHR-----RAETKARLPPPRPQRPAETKVP----EEIPPEVVQEYVDIMEE 526
               +PPP P         ++ A  PPP  Q P     P     E  PE+ Q +  +  +
Sbjct: 227 PPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRK 286

Query: 527 LLGPSLGATGEPE--------KQREEGKVKQPQEEDWTPPDP 560
             GP  G    P           R     + P      PP P
Sbjct: 287 TPGPVRGLAPPPPTSASPSLLSNRPPPPARDPPSRGAAPPPP 328



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 60/243 (24%), Positives = 79/243 (32%), Gaps = 60/243 (24%)

Query: 428 LPPPATPRLEP--RGPPAPEVVKQPVYLPS----KAGPKAQTACLPPPR----------- 470
           LPP    RL P   GPPAP  VK P   PS    + GP  Q+   PPP            
Sbjct: 209 LPPTPGQRLHPGREGPPAPPPVKPP---PSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGP 265

Query: 471 -----------PQR----------PVTKARRPPPQPHRRAETKARLPPPRPQRPAETKVP 509
                      PQR          PV     PPP     +    R PPP    P+    P
Sbjct: 266 SSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPPTSASPSLLSNRPPPPARDPPSRGAAP 325

Query: 510 EEIPPEVVQEYVDI--------MEELLGPSLGATGEPEKQREEGKVKQPQEEDWTPPDPG 561
              PP +     D         M     PS G    P  +   G           PP P 
Sbjct: 326 PPPPPVIRNGARDAPPPPPPYRMHGSEPPSRGKPPPPPSRTPAGPPP-------PPPPPL 378

Query: 562 LLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDFLALSQDLEQEEGLTLAQGAPS 621
              + D + + + F+   E+      +E+  +P+    F    Q +   +    A+GAP 
Sbjct: 379 RNGHRDSITTVRSFLDDFESKYSFHPVEDFPAPEEYKHF----QRIYPSKTNRAARGAPP 434

Query: 622 DAP 624
             P
Sbjct: 435 LPP 437



 Score = 37.7 bits (86), Expect = 0.032
 Identities = 32/114 (28%), Positives = 41/114 (35%), Gaps = 25/114 (21%)

Query: 426 QCLPPPATPRLEPRGPP----------APEVVKQPVYL---------------PSKAGPK 460
           Q L PP  P  +P G P          APE+ ++   L               P+ A P 
Sbjct: 246 QSLAPPPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPPTSASPS 305

Query: 461 AQTACLPPPRPQRPVTKARRPPPQPHRRAETKARLPPPRPQRPAETKVPEEIPP 514
             +   PPP    P   A  PPP P  R   +   PPP P R   ++ P    P
Sbjct: 306 LLSNRPPPPARDPPSRGAAPPPPPPVIRNGARDAPPPPPPYRMHGSEPPSRGKP 359



 Score = 30.4 bits (67), Expect = 5.1
 Identities = 32/116 (27%), Positives = 43/116 (37%), Gaps = 9/116 (7%)

Query: 431 PATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHRRAE 490
           P  PR++   P  P++ +      S  G K  ++  PPP P R       P P    +A 
Sbjct: 146 PELPRMQR--PSLPDLSRPNT--TSSTGMKHSSSAPPPPPPGRRANAPPTPLPMHSSKAP 201

Query: 491 TKAR---LPPPRPQR--PAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQ 541
              R   LPP   QR  P     P   P +     V+I     G SL     P +Q
Sbjct: 202 AYNREKPLPPTPGQRLHPGREGPPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQ 257



 Score = 29.6 bits (65), Expect = 8.8
 Identities = 11/21 (52%), Positives = 12/21 (57%)

Query: 277 LPLPPPPPPAAQLPPIVSQGN 297
           +P PPPPPP    PP   Q N
Sbjct: 3   IPPPPPPPPGPPPPPTFHQAN 23


>gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain
           1 isoform c [Homo sapiens]
          Length = 1450

 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 41/134 (30%), Positives = 58/134 (43%), Gaps = 22/134 (16%)

Query: 425 PQCLPPPATPRLEPRGPPAP------EVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKA 478
           P C   P+T   +P  PP P      E+   PV  P + GP      LP  + +  +  +
Sbjct: 126 PTCFTTPSTAAPDPVLPPLPAKRHLAELSVPPV--PPRTGPPRLLVSLPT-KEEESLLPS 182

Query: 479 RRPPPQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQ--------EYVDIMEELLGP 530
              PPQP    E  + LP   PQ P+    P EIPP+ V+        +Y ++ EE  GP
Sbjct: 183 LSSPPQPQSE-EPLSTLPQGPPQPPSPPPCPPEIPPKPVRLFPEFDDSDYDEVPEE--GP 239

Query: 531 SLGATGEPEKQREE 544
             GA      ++EE
Sbjct: 240 --GAPARVMTKKEE 251



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 39/144 (27%), Positives = 57/144 (39%), Gaps = 24/144 (16%)

Query: 430 PPATPRLEP------RGPPAPEVVKQPVY-------LPSKAGPKAQTACLPPPRPQRPVT 476
           P  TPR  P      R PP P    +P+        LP+      + +CLPP     P T
Sbjct: 75  PRPTPRPVPMKRHIFRSPPVPATPPEPLPTTTEDEGLPAAPPIPPRRSCLPPTCFTTPST 134

Query: 477 KARRP--PPQPHRRAETKARLPPPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGA 534
            A  P  PP P +R   +  +PP  P+           PP ++       EE L PSL +
Sbjct: 135 AAPDPVLPPLPAKRHLAELSVPPVPPRTG---------PPRLLVSLPTKEEESLLPSLSS 185

Query: 535 TGEPEKQREEGKVKQPQEEDWTPP 558
             +P+ +     + Q   +  +PP
Sbjct: 186 PPQPQSEEPLSTLPQGPPQPPSPP 209


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 49/172 (28%), Positives = 63/172 (36%), Gaps = 53/172 (30%)

Query: 427  CLPP----PATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARR-- 480
            C PP    P  PR   R PP+   +  P+  P       +   L P +PQ PV  +    
Sbjct: 1468 CPPPMKRKPGRPR---RSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDP 1524

Query: 481  ---------------PPPQPHRRAETKARLPPPRPQRPAE-TKVP----------EEIPP 514
                           PPP P        + PPP P  P E TK+P          E IPP
Sbjct: 1525 RTVTLDFRNAGIPAPPPPLP-------PQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPP 1577

Query: 515  ------EVVQEYVDIMEELLGPSLGATGEPEKQREEGKVKQPQEEDWTPPDP 560
                  EV +EY++     L  S G    P K+R E  V      + +PP P
Sbjct: 1578 GPRGRDEVTEEYME-----LAKSRGPWRRPPKKRHEDLVPPAGSPELSPPQP 1624



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 31/109 (28%), Positives = 40/109 (36%), Gaps = 7/109 (6%)

Query: 412 EEMQIQKSQWMKGP----QCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAG--PKAQTAC 465
           E+M+I   +    P     C P P           AP V+   + LP   G  P      
Sbjct: 637 EDMEISDDEMPSAPITSADC-PKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPP 695

Query: 466 LPPPRPQRPVTKARRPPPQPHRRAETKARLPPPRPQRPAETKVPEEIPP 514
            PPP+P  P+     PPP P   A     +PPP    P     P  +PP
Sbjct: 696 PPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPP 744



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 41/165 (24%), Positives = 58/165 (35%), Gaps = 17/165 (10%)

Query: 406  LEFEAEEEMQIQKSQWMKGPQCLPPPATP-----RLEPRGPPA-PEVVKQPVYLPSKAGP 459
            L  E E +++ +     + P  L  P  P       + R PP  P + ++   L S   P
Sbjct: 1185 LGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPP 1244

Query: 460  KAQTACLPPPRPQRPVTKARRPPPQPHRRAETKAR--LPPPRPQRPAETKVPEEIPPEVV 517
              +    PP  P+R         P+P        +  LPPPRP RP         PPE  
Sbjct: 1245 AKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSP------PPE-- 1296

Query: 518  QEYVDIMEELLGPS-LGATGEPEKQREEGKVKQPQEEDWTPPDPG 561
             E  D     + P  L     P      G + + Q  +  P  PG
Sbjct: 1297 PETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPG 1341



 Score = 34.7 bits (78), Expect = 0.27
 Identities = 38/145 (26%), Positives = 54/145 (37%), Gaps = 13/145 (8%)

Query: 151 PFTTPAPGPAHGPLLVTAGAPPGGPLVLSTFPSTPLVTEQDGCSPSGAGASNVFVQMRTE 210
           P   P PGP     L++  A     LV    P++  + E  G   SG        +M + 
Sbjct: 592 PRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDE--GQQSSGEDMEISDDEMPS- 648

Query: 211 VGPVKAAQA-QTLVLTQAPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMAAQVVGGTQAC 269
             P+ +A   + +V+T       AP  L   +  PPP      P  P             
Sbjct: 649 -APITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPP-------- 699

Query: 270 EGGWSQGLPLPPPPPPAAQLPPIVS 294
           + G+    PLPPPPPP     P V+
Sbjct: 700 QPGFPMPPPLPPPPPPPPPAHPAVT 724



 Score = 34.3 bits (77), Expect = 0.36
 Identities = 40/146 (27%), Positives = 57/146 (39%), Gaps = 17/146 (11%)

Query: 158  GPAHGPLLVTAGAPPGGPLVLSTFPSTPLVTEQDGCSPSG------AGASNVFVQMRTEV 211
            GP   P+L+  G P   PL L    + P V      +P+       A  ++    M+ + 
Sbjct: 1417 GPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKP 1476

Query: 212  GPVKAAQAQTLVLTQAPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMAAQVVGGTQACEG 271
            G  + +    L L   PLV    GA  G  +    LLL   P  PV  +     T   + 
Sbjct: 1477 GRPRRSPPSMLSL-DGPLVRPPAGAALGREL----LLLPGQPQTPVFPSTHDPRTVTLDF 1531

Query: 272  GWSQGLPLPPPP-----PPAAQLPPI 292
              + G+P PPPP     PP    PP+
Sbjct: 1532 R-NAGIPAPPPPLPPQPPPPPPPPPV 1556



 Score = 32.7 bits (73), Expect = 1.0
 Identities = 29/90 (32%), Positives = 36/90 (40%), Gaps = 21/90 (23%)

Query: 425  PQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKA------ 478
            PQ  PPP  P +EP   P  E+  Q    PS+A P       P PR +  VT+       
Sbjct: 1545 PQPPPPPPPPPVEPTKLPFKELDNQ---WPSEAIP-------PGPRGRDEVTEEYMELAK 1594

Query: 479  -----RRPPPQPHRRAETKARLPPPRPQRP 503
                 RRPP + H      A  P   P +P
Sbjct: 1595 SRGPWRRPPKKRHEDLVPPAGSPELSPPQP 1624



 Score = 30.8 bits (68), Expect = 3.9
 Identities = 26/89 (29%), Positives = 35/89 (39%), Gaps = 6/89 (6%)

Query: 430  PPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPP------ 483
            P A+P L   G P P  +  P+ L   A  +AQ     P  P  P   A  PPP      
Sbjct: 1418 PLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPG 1477

Query: 484  QPHRRAETKARLPPPRPQRPAETKVPEEI 512
            +P R   +   L  P  + PA   +  E+
Sbjct: 1478 RPRRSPPSMLSLDGPLVRPPAGAALGREL 1506


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.134    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,708,294
Number of Sequences: 37866
Number of extensions: 2393141
Number of successful extensions: 23973
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 278
Number of HSP's successfully gapped in prelim test: 1005
Number of HSP's that attempted gapping in prelim test: 13403
Number of HSP's gapped (non-prelim): 8368
length of query: 629
length of database: 18,247,518
effective HSP length: 108
effective length of query: 521
effective length of database: 14,157,990
effective search space: 7376312790
effective search space used: 7376312790
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press