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Search of human proteins with 116268101
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116268101 leucine rich repeat containing 62 [Homo sapiens]
(820 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116268101 leucine rich repeat containing 62 [Homo sapiens] 1655 0.0
gi|191252816 extracellular leucine-rich repeat and fibronectin t... 697 0.0
gi|11321571 slit homolog 3 [Homo sapiens] 97 8e-20
gi|188528675 slit homolog 1 [Homo sapiens] 97 8e-20
gi|40217820 slit and trk like 3 protein [Homo sapiens] 93 1e-18
gi|40255157 leucine-rich repeats and immunoglobulin-like domains... 90 1e-17
gi|209862903 leucine-rich repeats and immunoglobulin-like domain... 90 1e-17
gi|194306623 immunoglobulin superfamily containing leucine-rich ... 89 1e-17
gi|194306621 immunoglobulin superfamily containing leucine-rich ... 89 1e-17
gi|39930401 immunoglobulin superfamily containing leucine-rich r... 89 1e-17
gi|194306618 immunoglobulin superfamily containing leucine-rich ... 89 1e-17
gi|84781739 leucine-rich repeats and transmembrane domains 2 [Ho... 88 4e-17
gi|7662320 leucine-rich repeats and immunoglobulin-like domains ... 87 5e-17
gi|4759146 slit homolog 2 [Homo sapiens] 87 8e-17
gi|229089140 leucine rich repeat containing 24 [Homo sapiens] 86 1e-16
gi|239752702 PREDICTED: leucine rich repeat containing 38, parti... 86 2e-16
gi|239747236 PREDICTED: leucine rich repeat containing 38 [Homo ... 86 2e-16
gi|239741057 PREDICTED: leucine rich repeat containing 38 [Homo ... 86 2e-16
gi|41582239 immunoglobulin superfamily containing leucine-rich r... 86 2e-16
gi|5031809 immunoglobulin superfamily containing leucine-rich re... 86 2e-16
gi|4758460 glycoprotein V (platelet) [Homo sapiens] 85 2e-16
gi|139948432 adlican [Homo sapiens] 85 3e-16
gi|40217825 slit and trk like 6 [Homo sapiens] 84 5e-16
gi|15029530 leucine rich repeat containing 4 [Homo sapiens] 81 3e-15
gi|27436867 slit and trk like 4 protein [Homo sapiens] 81 4e-15
gi|12597641 leucine rich repeat containing 19 [Homo sapiens] 80 6e-15
gi|10190722 leucine-rich repeats and transmembrane domains 1 [Ho... 80 6e-15
gi|126517478 peroxidasin homolog-like [Homo sapiens] 80 8e-15
gi|109150416 peroxidasin [Homo sapiens] 80 1e-14
gi|205277468 leucine rich repeat containing 15 isoform a [Homo s... 79 1e-14
>gi|116268101 leucine rich repeat containing 62 [Homo sapiens]
Length = 820
Score = 1655 bits (4286), Expect = 0.0
Identities = 820/820 (100%), Positives = 820/820 (100%)
Query: 1 MLRLGLCAAALLCVCRPGAVRADCWLIEGDKGYVWLAICSQNQPPYETIPQHINSTVHDL 60
MLRLGLCAAALLCVCRPGAVRADCWLIEGDKGYVWLAICSQNQPPYETIPQHINSTVHDL
Sbjct: 1 MLRLGLCAAALLCVCRPGAVRADCWLIEGDKGYVWLAICSQNQPPYETIPQHINSTVHDL 60
Query: 61 RLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLSNLTE 120
RLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLSNLTE
Sbjct: 61 RLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLSNLTE 120
Query: 121 GMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMVC 180
GMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMVC
Sbjct: 121 GMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMVC 180
Query: 181 ELAGNPFNCECDLFGFLAWLVVFNNVTKNYDRLQCESPREFAGYPLLVPRPYHSLNAITV 240
ELAGNPFNCECDLFGFLAWLVVFNNVTKNYDRLQCESPREFAGYPLLVPRPYHSLNAITV
Sbjct: 181 ELAGNPFNCECDLFGFLAWLVVFNNVTKNYDRLQCESPREFAGYPLLVPRPYHSLNAITV 240
Query: 241 LQAKCRNGSLPARPVSHPTPYSTDAQREPDENSGFNPDEILSVEPPASSTTDASAGPAIK 300
LQAKCRNGSLPARPVSHPTPYSTDAQREPDENSGFNPDEILSVEPPASSTTDASAGPAIK
Sbjct: 241 LQAKCRNGSLPARPVSHPTPYSTDAQREPDENSGFNPDEILSVEPPASSTTDASAGPAIK 300
Query: 301 LHHVTFTSATLVVIIPHPYSKMYILVQYNNSYFSDVMTLKNKKEIVTLDKLRAHTEYTFC 360
LHHVTFTSATLVVIIPHPYSKMYILVQYNNSYFSDVMTLKNKKEIVTLDKLRAHTEYTFC
Sbjct: 301 LHHVTFTSATLVVIIPHPYSKMYILVQYNNSYFSDVMTLKNKKEIVTLDKLRAHTEYTFC 360
Query: 361 VTSLRNSRRFNHTCLTFTTRDPVPGDLAPSTSTTTHYIMTILGCLFGMVIVLGAVYYCLR 420
VTSLRNSRRFNHTCLTFTTRDPVPGDLAPSTSTTTHYIMTILGCLFGMVIVLGAVYYCLR
Sbjct: 361 VTSLRNSRRFNHTCLTFTTRDPVPGDLAPSTSTTTHYIMTILGCLFGMVIVLGAVYYCLR 420
Query: 421 KRRMQEEKQKSVNVKKTILEMRYGADVDAGSIVHAAQKLGEPPVLPVSRMASIPSMIGEK 480
KRRMQEEKQKSVNVKKTILEMRYGADVDAGSIVHAAQKLGEPPVLPVSRMASIPSMIGEK
Sbjct: 421 KRRMQEEKQKSVNVKKTILEMRYGADVDAGSIVHAAQKLGEPPVLPVSRMASIPSMIGEK 480
Query: 481 LPTAKGLEAGLDTPKVATKGNYIEVRTGAGGDGLARPEDDLPDLENGQGSAAEISTIAKE 540
LPTAKGLEAGLDTPKVATKGNYIEVRTGAGGDGLARPEDDLPDLENGQGSAAEISTIAKE
Sbjct: 481 LPTAKGLEAGLDTPKVATKGNYIEVRTGAGGDGLARPEDDLPDLENGQGSAAEISTIAKE 540
Query: 541 VDKVNQIINNCIDALKLDSASFLGGGSSSGDPELAFECQSLPAAAAASSATGPGALERPS 600
VDKVNQIINNCIDALKLDSASFLGGGSSSGDPELAFECQSLPAAAAASSATGPGALERPS
Sbjct: 541 VDKVNQIINNCIDALKLDSASFLGGGSSSGDPELAFECQSLPAAAAASSATGPGALERPS 600
Query: 601 FLSPPYKESSHHPLQRQLSADAAVTRKTCSVSSSGSIKSAKVFSLDVPDHPAATGLAKGD 660
FLSPPYKESSHHPLQRQLSADAAVTRKTCSVSSSGSIKSAKVFSLDVPDHPAATGLAKGD
Sbjct: 601 FLSPPYKESSHHPLQRQLSADAAVTRKTCSVSSSGSIKSAKVFSLDVPDHPAATGLAKGD 660
Query: 661 SKYIEKGSPLNSPLDRLPLVPAGSGGGSGGGGGIHHLEVKPAYHCSEHRHSFPALYYEEG 720
SKYIEKGSPLNSPLDRLPLVPAGSGGGSGGGGGIHHLEVKPAYHCSEHRHSFPALYYEEG
Sbjct: 661 SKYIEKGSPLNSPLDRLPLVPAGSGGGSGGGGGIHHLEVKPAYHCSEHRHSFPALYYEEG 720
Query: 721 ADSLSQRVSFLKPLTRSKRDSTYSQLSPRHYYSGYSSSPEYSSESTHKIWERFRPYKKHH 780
ADSLSQRVSFLKPLTRSKRDSTYSQLSPRHYYSGYSSSPEYSSESTHKIWERFRPYKKHH
Sbjct: 721 ADSLSQRVSFLKPLTRSKRDSTYSQLSPRHYYSGYSSSPEYSSESTHKIWERFRPYKKHH 780
Query: 781 REEVYMAAGHALRKKVQFAKDEDLHDILDYWKGVSAQQKL 820
REEVYMAAGHALRKKVQFAKDEDLHDILDYWKGVSAQQKL
Sbjct: 781 REEVYMAAGHALRKKVQFAKDEDLHDILDYWKGVSAQQKL 820
>gi|191252816 extracellular leucine-rich repeat and fibronectin type
III domain containing 1 [Homo sapiens]
Length = 828
Score = 697 bits (1799), Expect = 0.0
Identities = 413/860 (48%), Positives = 521/860 (60%), Gaps = 85/860 (9%)
Query: 4 LGLCAAALLCVCRPGAVRADCWLIEGDKGYVWLAICSQNQPPYETIPQHINSTVHDLRLN 63
L +C AA + G RADCWLIEGDKG+VWLAICSQNQPPYE IPQ INST+ DLRLN
Sbjct: 9 LWVCVAAATLLHAGGLARADCWLIEGDKGFVWLAICSQNQPPYEAIPQQINSTIVDLRLN 68
Query: 64 ENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLSNLTEGML 123
EN++++V Y+SL+RFGNLT LNLTKNEI YIEDGAF GQ +LQVLQLGYN+L NLTEGML
Sbjct: 69 ENRIRSVQYASLSRFGNLTYLNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRLRNLTEGML 128
Query: 124 RGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMVCELA 183
RG+ +L++L++Q NLIEVV ++F ECP++++IDLS NR+ +L+ TFA LA L VCEL
Sbjct: 129 RGLGKLEYLYLQANLIEVVMASSFWECPNIVNIDLSMNRIQQLNSGTFAGLAKLSVCELY 188
Query: 184 GNPFNCECDLFGFLAWLVVFNNVTKNYDRLQCESPREFAGYPLLVPRPYHSLNAITVLQA 243
NPF C C+L GFL WL F N T+ YDR+QCESP ++GY LL + ++ LQ+
Sbjct: 189 SNPFYCSCELLGFLRWLAAFTNATQTYDRMQCESPPVYSGYYLLGQGRRGHRSILSKLQS 248
Query: 244 KCRNGSLPARPVSHPTPYSTDAQ--REPD-------------ENSGFNPDEILSVEPPAS 288
C S A V P P S +Q R P ++ F+ D + +
Sbjct: 249 VCTEDSYAAEVVGPPRPASGRSQPGRSPPPPPPPEPSDMPCADDECFSGDGTTPLVALPT 308
Query: 289 STTDASAGPAIKLHHVTFTSATLVVIIPHPYSKMYILVQYNNSYFSDVMTLKNKKEIVTL 348
T A A P IK+ +T SAT+ V +P P+ +MY L +NNS S V L +E + L
Sbjct: 309 LATQAEARPLIKVKQLTQNSATITVQLPSPFHRMYTLEHFNNSKASTVSRLTKAQEEIRL 368
Query: 349 DKLRAHTEYTFCVTSLRNSRRFNHTCLTF-TTRDPVPGDLAPSTSTTTHYIMTILGCLFG 407
L T YT+CV S R NHTCLT R P P PS ST THYIMTILGCLFG
Sbjct: 369 TNLFTLTNYTYCVVSTSAGLRHNHTCLTICLPRLPSPPGPVPSPSTATHYIMTILGCLFG 428
Query: 408 MVIVLGAVYYCLRKRRMQEEKQKSV-------NVKKTILEMRYGADVDAGSIVHAAQKLG 460
MV+VLGAVYYCLR+RR QEEK K ++KKTI+E++YG +++A + L
Sbjct: 429 MVLVLGAVYYCLRRRRRQEEKHKKAASAAAAGSLKKTIIELKYGPELEAPGLA----PLS 484
Query: 461 EPPVLPVSRMASIPSMIGEKLPTAKGLEAGLDTPKVATKGNYIEVRTGAGGD----GLAR 516
+ P+L + IP + L DTPK A+KG+Y+EVRTG + L R
Sbjct: 485 QGPLLGPEAVTRIPYLPAAGEVEQYKLVESADTPK-ASKGSYMEVRTGDPPERRDCELGR 543
Query: 517 PEDDLPDLENGQGSAAEISTIAKEVDKVNQIINNCIDALKLDSASFLG---GGSSSGDPE 573
P D Q S AEISTIAKEVDKVNQIINNCIDALK +S SF G G S +P
Sbjct: 544 PGPD------SQSSVAEISTIAKEVDKVNQIINNCIDALKSESTSFQGVKSGPVSVAEPP 597
Query: 574 LAFECQSLPAAAAASSATGPGALERPSFLSPPYKESSHHPLQRQLSADAAVTRKTCSVSS 633
L + L A + FL+P YK++ H LQR S +AA + S SS
Sbjct: 598 LVLLSEPLAA--------------KHGFLAPGYKDAFGHSLQRHHSVEAAGPPR-ASTSS 642
Query: 634 SGSIKSAKVFSLD-VPDHPAATGLAKGDSKYIEKGSPLNSPLDRLPLVPAGSGGGSGGGG 692
SGS++S + F + V H AA ++KYIEKGSP + L + PA +
Sbjct: 643 SGSVRSPRAFRAEAVGVHKAAA----AEAKYIEKGSPAADAI--LTVTPAAA-------- 688
Query: 693 GIHHLEVKPAYHCSEHRHSFPALYYEEGA-----------DSLSQRVSFLKPLTRSK-RD 740
+ E + EHRHS+P + E + L ++ S L+PLTR + RD
Sbjct: 689 -VLRAEAEKGRQYGEHRHSYPGSHPAEPPAPPGPPPPPPHEGLGRKASILEPLTRPRPRD 747
Query: 741 STYSQLSPRHYYSGYSSSPEYSSESTHKIWERFRPYKKHHR-EEVYMAAGHALRKKVQFA 799
YSQLSP+++ YSSSPEY+ ++ IWERFR ++ H+ EE +MAAGHALRKKVQFA
Sbjct: 748 LAYSQLSPQYHSLSYSSSPEYTCRASQSIWERFRLSRRRHKEEEEFMAAGHALRKKVQFA 807
Query: 800 KDEDLHDILDYWKGVSAQQK 819
KDEDLHDILDYWKGVSAQ K
Sbjct: 808 KDEDLHDILDYWKGVSAQHK 827
>gi|11321571 slit homolog 3 [Homo sapiens]
Length = 1523
Score = 96.7 bits (239), Expect = 8e-20
Identities = 54/153 (35%), Positives = 84/153 (54%), Gaps = 1/153 (0%)
Query: 49 IPQHINSTVHDLRLNENKLKAVLYSSL-NRFGNLTDLNLTKNEISYIEDGAFLGQSSLQV 107
IP H+ V DLRLN+N++ + + + + NL +NL+ N+I + +GAF G +S+Q
Sbjct: 526 IPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQE 585
Query: 108 LQLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLD 167
L L N+L + + RG+S L+ L ++ NLI V+ F+ S+ + L NR++ +
Sbjct: 586 LMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTIT 645
Query: 168 GATFASLASLMVCELAGNPFNCECDLFGFLAWL 200
F +L SL L NPFNC C L WL
Sbjct: 646 PGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWL 678
Score = 89.4 bits (220), Expect = 1e-17
Identities = 55/174 (31%), Positives = 90/174 (51%), Gaps = 3/174 (1%)
Query: 49 IPQHINSTVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVL 108
IP ++ + ++RL +N +KA+ + ++ L ++++KN+IS I AF G SL L
Sbjct: 301 IPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSL 360
Query: 109 QLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDG 168
L NK++ + +G+ G+ LQ L + N I + F + +L + L N+L +
Sbjct: 361 VLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISK 420
Query: 169 ATFASLASLMVCELAGNPFNCECDLFGFLAWLVVFNNVTKNYDRLQCESPREFA 222
FA L S+ LA NPF C+C L +LA + N + + R C SPR A
Sbjct: 421 GLFAPLQSIQTLHLAQNPFVCDCHL-KWLADYLQDNPIETSGAR--CSSPRRLA 471
Score = 58.5 bits (140), Expect = 2e-08
Identities = 35/104 (33%), Positives = 58/104 (55%)
Query: 60 LRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLSNLT 119
LRLN+NKL+ + LT L+L++N+I I AF G + ++ LQL N +S +
Sbjct: 114 LRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIE 173
Query: 120 EGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRL 163
+G R + L+ L + +N I + T+F+ P + ++ L SN L
Sbjct: 174 DGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHL 217
Score = 58.2 bits (139), Expect = 3e-08
Identities = 38/137 (27%), Positives = 63/137 (45%)
Query: 49 IPQHINSTVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVL 108
+P+ I L L+ N + + NL L+L N++S IE GAF L+ L
Sbjct: 55 VPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERL 114
Query: 109 QLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDG 168
+L NKL L E + + +L L + N I+ + AF + ++ L +N +S ++
Sbjct: 115 RLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIED 174
Query: 169 ATFASLASLMVCELAGN 185
F +L L + L N
Sbjct: 175 GAFRALRDLEILTLNNN 191
Score = 52.0 bits (123), Expect = 2e-06
Identities = 38/129 (29%), Positives = 55/129 (42%), Gaps = 4/129 (3%)
Query: 105 LQVLQLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLS 164
L ++ L N +S LT MS L L + +N + + AF+ SL + L N +S
Sbjct: 777 LTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDIS 836
Query: 165 RLDGATFASLASLMVCELAGNPFNCECDLFGFLAWLVVFNNVTKNYDRLQCESPREFAGY 224
+ +F L SL L NP +C+C L W+ K +C SP A
Sbjct: 837 SVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEWV---KAGYKEPGIARCSSPEPMAD- 892
Query: 225 PLLVPRPYH 233
LL+ P H
Sbjct: 893 RLLLTTPTH 901
>gi|188528675 slit homolog 1 [Homo sapiens]
Length = 1534
Score = 96.7 bits (239), Expect = 8e-20
Identities = 57/179 (31%), Positives = 95/179 (53%), Gaps = 4/179 (2%)
Query: 49 IPQHINSTVHDLRLNENKLKAVLYSSL-NRFGNLTDLNLTKNEISYIEDGAFLGQSSLQV 107
IP+ I + +LRLN N++ + + + + +L +NL+ N++S IEDGAF G +S+
Sbjct: 534 IPERIPQSTAELRLNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSE 593
Query: 108 LQLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLD 167
L L N+L ++ GM RG+ L+ L +++N I + +F+ ++ + L N+++ +
Sbjct: 594 LHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVS 653
Query: 168 GATFASLASLMVCELAGNPFNCECDLFGFLAWLVVFNNVTKNYDRLQCESPREFAGYPL 226
F +L SL L NPFNC C L WL VT N +C++P PL
Sbjct: 654 PGAFDTLQSLSTLNLLANPFNCNCQLAWLGGWLRKRKIVTGN---PRCQNPDFLRQIPL 709
Score = 92.8 bits (229), Expect = 1e-18
Identities = 56/175 (32%), Positives = 89/175 (50%), Gaps = 5/175 (2%)
Query: 49 IPQHINSTVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVL 108
IP ++ T+ ++RL N +K++ + + + L ++L+ N+I+ I AF G SL L
Sbjct: 303 IPANLPETMTEIRLELNGIKSIPPGAFSPYRKLRRIDLSNNQIAEIAPDAFQGLRSLNSL 362
Query: 109 QLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDG 168
L NK+++L G+ G+ LQ L + N I + P AF + +L + L N++ L
Sbjct: 363 VLYGNKITDLPRGVFGGLYTLQLLLLNANKINCIRPDAFQDLQNLSLLSLYDNKIQSLAK 422
Query: 169 ATFASLASLMVCELAGNPFNCECDLFGFLAWLVVFNNVTK-NYDRLQCESPREFA 222
TF SL ++ LA NPF C+C+ L WL F +C SPR A
Sbjct: 423 GTFTSLRAIQTLHLAQNPFICDCN----LKWLADFLRTNPIETSGARCASPRRLA 473
Score = 67.8 bits (164), Expect = 4e-11
Identities = 48/170 (28%), Positives = 76/170 (44%), Gaps = 9/170 (5%)
Query: 80 NLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLSNLTEGMLRGMSRLQFLFVQHNLI 139
N+T+L L N+ + + G LQ++ L NK+S+L+ MS+L L + +N +
Sbjct: 762 NVTELYLDGNQFTLVP-GQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQLTTLILSYNAL 820
Query: 140 EVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMVCELAGNPFNCECDLFGFLAW 199
+ + P AF SL + L N +S L FA + SL + NP C+C L +W
Sbjct: 821 QCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPLYCDCHLRWLSSW 880
Query: 200 LVVFNNVTKNYDRLQCESPREFAGYPLLVPRPYHSLNA----ITVLQAKC 245
+ K +C P++ G LL+ P +QAKC
Sbjct: 881 V---KTGYKEPGIARCAGPQDMEG-KLLLTTPAKKFECQGPPTLAVQAKC 926
Score = 61.2 bits (147), Expect = 4e-09
Identities = 49/183 (26%), Positives = 74/183 (40%), Gaps = 19/183 (10%)
Query: 3 RLGLCAAALLCVCRPGAVRADCWLIEGDKGYVWLAICSQNQPPYETIPQHINSTVHDLRL 62
RLG A LC C V DC + + IP++I L L
Sbjct: 28 RLGASACPALCTCTGTTV--DC-----------------HGTGLQAIPKNIPRNTERLEL 68
Query: 63 NENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLSNLTEGM 122
N N + + + L L L +N+I +E GAF L+ L+L N+L L E +
Sbjct: 69 NGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELL 128
Query: 123 LRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMVCEL 182
+ L L + N I+ + AF L ++ L N++S ++ F +L L V L
Sbjct: 129 FQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTL 188
Query: 183 AGN 185
N
Sbjct: 189 NNN 191
Score = 53.9 bits (128), Expect = 6e-07
Identities = 35/141 (24%), Positives = 62/141 (43%)
Query: 60 LRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLSNLT 119
L+L EN++ AV + + L L L +N++ + + F +L L L N + +
Sbjct: 90 LQLMENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIP 149
Query: 120 EGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMV 179
RG + L+ L + N I + AF L + L++N ++ + ++F + L
Sbjct: 150 RKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRT 209
Query: 180 CELAGNPFNCECDLFGFLAWL 200
L N C+C L WL
Sbjct: 210 FRLHSNHLFCDCHLAWLSQWL 230
Score = 47.8 bits (112), Expect = 4e-05
Identities = 38/133 (28%), Positives = 55/133 (41%), Gaps = 5/133 (3%)
Query: 80 NLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLSNLTEGMLRGMSRLQFLFVQHNLI 139
N L L N I+ I F G L+VLQL N++ + G M L+ L + N +
Sbjct: 62 NTERLELNGNNITRIHKNDFAGLKQLRVLQLMENQIGAVERGAFDDMKELERLRLNRNQL 121
Query: 140 EVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMVCELAGNPFNC-ECDLFGFLA 198
++ F +L +DLS N + + F L +L N +C E F L
Sbjct: 122 HMLPELLFQNNQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALR 181
Query: 199 WLVVF----NNVT 207
L V NN+T
Sbjct: 182 GLEVLTLNNNNIT 194
Score = 45.4 bits (106), Expect = 2e-04
Identities = 26/84 (30%), Positives = 43/84 (51%)
Query: 54 NSTVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYN 113
N + L L+EN ++A+ + +L +L L KN+IS IE+GAF L+VL L N
Sbjct: 132 NQALSRLDLSENAIQAIPRKAFRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNN 191
Query: 114 KLSNLTEGMLRGMSRLQFLFVQHN 137
++ + M +L+ + N
Sbjct: 192 NITTIPVSSFNHMPKLRTFRLHSN 215
>gi|40217820 slit and trk like 3 protein [Homo sapiens]
Length = 977
Score = 92.8 bits (229), Expect = 1e-18
Identities = 61/196 (31%), Positives = 97/196 (49%), Gaps = 27/196 (13%)
Query: 47 ETIPQHINSTVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQ 106
E +P+ +N+ L L+ N ++ + S F +L L+L N ISY++DGAF+ +L+
Sbjct: 402 ELLPRPLNAK--KLYLSSNLIQKIYRSDFWNFSSLDLLHLGNNRISYVQDGAFINLPNLK 459
Query: 107 VLQLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRL 166
L L N + LT GM RG+ L +L+ + N+I + P AFS P+L + L++N L L
Sbjct: 460 SLFLNGNDIEKLTPGMFRGLQSLHYLYFEFNVIREIQPAAFSLMPNLKLLFLNNNLLRTL 519
Query: 167 DGATFAS------------------------LASLMVCELAGNPFNCECDLFGFLAWLVV 202
FA L +++ +L NP++C CDL F W+
Sbjct: 520 PTDAFAGTSLARLNLRKNYFLYLPVAGVLEHLNAIVQIDLNENPWDCTCDLVPFKQWIET 579
Query: 203 FNNVTKNYDRLQCESP 218
++V+ D L C SP
Sbjct: 580 ISSVSVVGDVL-CRSP 594
Score = 81.3 bits (199), Expect = 3e-15
Identities = 57/177 (32%), Positives = 85/177 (48%), Gaps = 5/177 (2%)
Query: 52 HINSTVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLG 111
H+N+ V + L N L+ + + N L L L +N++ + FLG SL+ LQ
Sbjct: 99 HLNNAV-SINLGNNALQDIQTGAFNGLKILKRLYLHENKLDVFRNDTFLGLESLEYLQAD 157
Query: 112 YNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRL--DGA 169
YN + + G R +S+L+ L + NLI ++ PT + SL +DL NRL L G
Sbjct: 158 YNVIKRIESGAFRNLSKLRVLILNDNLIPML-PTNLFKAVSLTHLDLRGNRLKVLFYRGM 216
Query: 170 TFASLASLMVCELAGNPFNCECDLFGFLAWLVVFNNVTKNYDRLQCESPREFAGYPL 226
SLM +L NP+NC C++ +WL T + CE+P F G L
Sbjct: 217 LDHIGRSLMELQLEENPWNCTCEIVQLKSWLERI-PYTALVGDITCETPFHFHGKDL 272
>gi|40255157 leucine-rich repeats and immunoglobulin-like domains 3
isoform 2 [Homo sapiens]
Length = 1119
Score = 89.7 bits (221), Expect = 1e-17
Identities = 47/126 (37%), Positives = 73/126 (57%)
Query: 60 LRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLSNLT 119
L LN NK+K V + G L L + +N ++ + DGAF G S++++LQL +N L+ +T
Sbjct: 220 LELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEIT 279
Query: 120 EGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMV 179
+G L G+ LQ L + N I ++P A+ C L +DL+ N LSRLD ++F L+ L
Sbjct: 280 KGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNT 339
Query: 180 CELAGN 185
+ N
Sbjct: 340 LHIGNN 345
Score = 71.2 bits (173), Expect = 4e-12
Identities = 50/202 (24%), Positives = 87/202 (43%), Gaps = 29/202 (14%)
Query: 57 VHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLS 116
+ +L L++N + + + L++L+LT N +S ++D +FLG S L L +G N++S
Sbjct: 289 LQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVS 348
Query: 117 NLTEGMLRGMS---------------------------RLQFLFVQHNLIEVVTPTAFSE 149
+ + RG+S +L+ L +Q N I +T AF+
Sbjct: 349 YIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTG 408
Query: 150 CPSLISIDLSSNRLSRLDGATFASLASLMVCELAGNPFNCECDLFGFLAWLVVFNNVTKN 209
+L +DLS N + L G F+ + L L + C+C L W V N ++
Sbjct: 409 LDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLLCDCQLKWLPQW--VAENNFQS 466
Query: 210 YDRLQCESPREFAGYPLLVPRP 231
+ C P+ G + P
Sbjct: 467 FVNASCAHPQLLKGRSIFAVSP 488
Score = 52.0 bits (123), Expect = 2e-06
Identities = 41/135 (30%), Positives = 65/135 (48%), Gaps = 5/135 (3%)
Query: 55 STVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNK 114
S + L+L+ N L + L L +L+L++N I+ I A+ L L L +N
Sbjct: 263 SNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNH 322
Query: 115 LSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLS----RLDGAT 170
LS L + G+S L L + +N + + AF SL ++DL +N +S ++GA
Sbjct: 323 LSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGA- 381
Query: 171 FASLASLMVCELAGN 185
F+ L L L GN
Sbjct: 382 FSGLDKLRRLILQGN 396
Score = 41.6 bits (96), Expect = 0.003
Identities = 39/140 (27%), Positives = 73/140 (52%), Gaps = 8/140 (5%)
Query: 49 IPQHINSTVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLG--QSSLQ 106
+P+ + S V L L+ N+L + SS++ +L ++ L NE+ I + LG +++
Sbjct: 68 LPEPLPSWVARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPN---LGPVSANIT 124
Query: 107 VLQLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRL 166
+L L N++ + L+ L+ L + N I + TAF L + L+SNR++ +
Sbjct: 125 LLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISEL-QTAFPAL-QLKYLYLNSNRVTSM 182
Query: 167 DGATFASLA-SLMVCELAGN 185
+ F +LA +L+V +L N
Sbjct: 183 EPGYFDNLANTLLVLKLNRN 202
>gi|209862903 leucine-rich repeats and immunoglobulin-like domains 3
isoform 1 [Homo sapiens]
Length = 1059
Score = 89.7 bits (221), Expect = 1e-17
Identities = 47/126 (37%), Positives = 73/126 (57%)
Query: 60 LRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLSNLT 119
L LN NK+K V + G L L + +N ++ + DGAF G S++++LQL +N L+ +T
Sbjct: 160 LELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEIT 219
Query: 120 EGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMV 179
+G L G+ LQ L + N I ++P A+ C L +DL+ N LSRLD ++F L+ L
Sbjct: 220 KGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNT 279
Query: 180 CELAGN 185
+ N
Sbjct: 280 LHIGNN 285
Score = 71.2 bits (173), Expect = 4e-12
Identities = 50/202 (24%), Positives = 87/202 (43%), Gaps = 29/202 (14%)
Query: 57 VHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLS 116
+ +L L++N + + + L++L+LT N +S ++D +FLG S L L +G N++S
Sbjct: 229 LQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVS 288
Query: 117 NLTEGMLRGMS---------------------------RLQFLFVQHNLIEVVTPTAFSE 149
+ + RG+S +L+ L +Q N I +T AF+
Sbjct: 289 YIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTG 348
Query: 150 CPSLISIDLSSNRLSRLDGATFASLASLMVCELAGNPFNCECDLFGFLAWLVVFNNVTKN 209
+L +DLS N + L G F+ + L L + C+C L W V N ++
Sbjct: 349 LDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLLCDCQLKWLPQW--VAENNFQS 406
Query: 210 YDRLQCESPREFAGYPLLVPRP 231
+ C P+ G + P
Sbjct: 407 FVNASCAHPQLLKGRSIFAVSP 428
Score = 52.0 bits (123), Expect = 2e-06
Identities = 41/135 (30%), Positives = 65/135 (48%), Gaps = 5/135 (3%)
Query: 55 STVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNK 114
S + L+L+ N L + L L +L+L++N I+ I A+ L L L +N
Sbjct: 203 SNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNH 262
Query: 115 LSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLS----RLDGAT 170
LS L + G+S L L + +N + + AF SL ++DL +N +S ++GA
Sbjct: 263 LSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGA- 321
Query: 171 FASLASLMVCELAGN 185
F+ L L L GN
Sbjct: 322 FSGLDKLRRLILQGN 336
Score = 36.6 bits (83), Expect = 0.097
Identities = 35/127 (27%), Positives = 66/127 (51%), Gaps = 8/127 (6%)
Query: 62 LNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLG--QSSLQVLQLGYNKLSNLT 119
L+ N+L + SS++ +L ++ L NE+ I + LG +++ +L L N++ +
Sbjct: 21 LSHNRLSFIKASSMSHLQSLREVKLNNNELETIPN---LGPVSANITLLSLAGNRIVEIL 77
Query: 120 EGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLA-SLM 178
L+ L+ L + N I + TAF L + L+SNR++ ++ F +LA +L+
Sbjct: 78 PEHLKEFQSLETLDLSSNNISEL-QTAFPAL-QLKYLYLNSNRVTSMEPGYFDNLANTLL 135
Query: 179 VCELAGN 185
V +L N
Sbjct: 136 VLKLNRN 142
Score = 35.4 bits (80), Expect = 0.22
Identities = 27/100 (27%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Query: 70 VLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLSNLTEGMLRGMSRL 129
+L SL +++ +L+ N +S+I+ + SL+ ++L N+L + + + +
Sbjct: 5 LLLFSLCLLFHISRPDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPN-LGPVSANI 63
Query: 130 QFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDGA 169
L + N I + P E SL ++DLSSN +S L A
Sbjct: 64 TLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQTA 103
>gi|194306623 immunoglobulin superfamily containing leucine-rich
repeat 2 [Homo sapiens]
Length = 745
Score = 89.4 bits (220), Expect = 1e-17
Identities = 55/178 (30%), Positives = 85/178 (47%)
Query: 49 IPQHINSTVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVL 108
+P+ + + V L L+ NK+ + + +T L L NE+ +E GA S L+ L
Sbjct: 45 VPEGLPANVTTLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNL 104
Query: 109 QLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDG 168
L +N +S+ LR +S LQ L + HN + + A P L S+ +++NRL L
Sbjct: 105 DLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAP 164
Query: 169 ATFASLASLMVCELAGNPFNCECDLFGFLAWLVVFNNVTKNYDRLQCESPREFAGYPL 226
TF +L++L +L NPF+C C L AW D + C SP G P+
Sbjct: 165 GTFDALSALSHLQLYHNPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPV 222
>gi|194306621 immunoglobulin superfamily containing leucine-rich
repeat 2 [Homo sapiens]
Length = 745
Score = 89.4 bits (220), Expect = 1e-17
Identities = 55/178 (30%), Positives = 85/178 (47%)
Query: 49 IPQHINSTVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVL 108
+P+ + + V L L+ NK+ + + +T L L NE+ +E GA S L+ L
Sbjct: 45 VPEGLPANVTTLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNL 104
Query: 109 QLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDG 168
L +N +S+ LR +S LQ L + HN + + A P L S+ +++NRL L
Sbjct: 105 DLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAP 164
Query: 169 ATFASLASLMVCELAGNPFNCECDLFGFLAWLVVFNNVTKNYDRLQCESPREFAGYPL 226
TF +L++L +L NPF+C C L AW D + C SP G P+
Sbjct: 165 GTFDALSALSHLQLYHNPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPV 222
>gi|39930401 immunoglobulin superfamily containing leucine-rich
repeat 2 [Homo sapiens]
Length = 745
Score = 89.4 bits (220), Expect = 1e-17
Identities = 55/178 (30%), Positives = 85/178 (47%)
Query: 49 IPQHINSTVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVL 108
+P+ + + V L L+ NK+ + + +T L L NE+ +E GA S L+ L
Sbjct: 45 VPEGLPANVTTLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNL 104
Query: 109 QLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDG 168
L +N +S+ LR +S LQ L + HN + + A P L S+ +++NRL L
Sbjct: 105 DLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAP 164
Query: 169 ATFASLASLMVCELAGNPFNCECDLFGFLAWLVVFNNVTKNYDRLQCESPREFAGYPL 226
TF +L++L +L NPF+C C L AW D + C SP G P+
Sbjct: 165 GTFDALSALSHLQLYHNPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPV 222
>gi|194306618 immunoglobulin superfamily containing leucine-rich
repeat 2 [Homo sapiens]
Length = 745
Score = 89.4 bits (220), Expect = 1e-17
Identities = 55/178 (30%), Positives = 85/178 (47%)
Query: 49 IPQHINSTVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVL 108
+P+ + + V L L+ NK+ + + +T L L NE+ +E GA S L+ L
Sbjct: 45 VPEGLPANVTTLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNL 104
Query: 109 QLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDG 168
L +N +S+ LR +S LQ L + HN + + A P L S+ +++NRL L
Sbjct: 105 DLSHNFISSFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAP 164
Query: 169 ATFASLASLMVCELAGNPFNCECDLFGFLAWLVVFNNVTKNYDRLQCESPREFAGYPL 226
TF +L++L +L NPF+C C L AW D + C SP G P+
Sbjct: 165 GTFDALSALSHLQLYHNPFHCGCGLVWLQAWAASTRVSLPEPDSIACASPPALQGVPV 222
>gi|84781739 leucine-rich repeats and transmembrane domains 2 [Homo
sapiens]
Length = 370
Score = 87.8 bits (216), Expect = 4e-17
Identities = 64/222 (28%), Positives = 101/222 (45%), Gaps = 6/222 (2%)
Query: 48 TIPQHINSTVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQV 107
T+P + + L L NKL A+ + +L L+L+ N + + F ++L
Sbjct: 61 TVPPDVPAATRTLLLLNNKLSALPSWAFANLSSLQRLDLSNNFLDRLPRSIFGDLTNLTE 120
Query: 108 LQLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLD 167
LQL N + L +LR L+ L + N + + P F +L S+ L SNRL LD
Sbjct: 121 LQLRNNSIRTLDRDLLRHSPLLRHLDLSINGLAQLPPGLFDGLLALRSLSLRSNRLQNLD 180
Query: 168 GATFASLASLMVCELAGNPFNCECDLFGFLAWLVVFNNVTKNYDRLQCESPREFAGYPLL 227
TF LA+L + ++ NP+ C+C+L F W+ F+ D+L C P+E G +
Sbjct: 181 RLTFEPLANLQLLQVGDNPWECDCNLREFKHWMEWFSYRGGRLDQLACTLPKELRGKDMR 240
Query: 228 VPRPYHSLNAITVLQAKCRNGSLPARPVSHPTPYSTDAQREP 269
+ P N + L+ + + L P P T A EP
Sbjct: 241 MV-PMEMFNYCSQLEDENSSAGLDI-----PGPPCTKASPEP 276
>gi|7662320 leucine-rich repeats and immunoglobulin-like domains 2
[Homo sapiens]
Length = 1065
Score = 87.4 bits (215), Expect = 5e-17
Identities = 56/166 (33%), Positives = 87/166 (52%), Gaps = 3/166 (1%)
Query: 36 LAICSQNQPPYETIPQHINSTVH--DLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISY 93
L + N+ IP I H L L N++K V + +L L + +N IS
Sbjct: 194 LLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISK 253
Query: 94 IEDGAFLGQSSLQVLQLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSL 153
++DGAF G ++++ L+L +N L+ + +G L G+ LQ L+V N IE ++P A+ C L
Sbjct: 254 LKDGAFFGLNNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRL 313
Query: 154 ISIDLSSNRLSRLDGATFASLASLMVCELAGNPFNCECD-LFGFLA 198
+DLS N+L+RLD + F L+ L L N D +F FL+
Sbjct: 314 SELDLSYNQLTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLS 359
Score = 53.9 bits (128), Expect = 6e-07
Identities = 41/130 (31%), Positives = 66/130 (50%), Gaps = 3/130 (2%)
Query: 57 VHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLG-QSSLQVLQLGYNKL 115
+ L L+ N + + SS R L LNL+ N I+ +E G F SSL V++L N++
Sbjct: 146 LESLDLSSNIISEIKTSSFPRM-QLKYLNLSNNRITTLEAGCFDNLSSSLLVVKLNRNRM 204
Query: 116 SNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLA 175
S + + + + LQFL ++ N I++V F SL S+ + N +S+L F L
Sbjct: 205 SMIPPKIFK-LPHLQFLELKRNRIKIVEGLTFQGLDSLRSLKMQRNGISKLKDGAFFGLN 263
Query: 176 SLMVCELAGN 185
++ EL N
Sbjct: 264 NMEELELEHN 273
Score = 47.4 bits (111), Expect = 5e-05
Identities = 40/134 (29%), Positives = 62/134 (46%), Gaps = 3/134 (2%)
Query: 55 STVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNK 114
+ + +L L N L V L L L +++N I I A+ L L L YN+
Sbjct: 263 NNMEELELEHNNLTRVNKGWLYGLRMLQQLYVSQNAIERISPDAWEFCQRLSELDLSYNQ 322
Query: 115 LSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLS-RLDGAT--F 171
L+ L E G+S L+ L + N + + F +L ++DL +N +S ++ A+ F
Sbjct: 323 LTRLDESAFVGLSLLERLNLGDNRVTHIADGVFRFLSNLQTLDLRNNEISWAIEDASEAF 382
Query: 172 ASLASLMVCELAGN 185
A L SL L GN
Sbjct: 383 AGLTSLTKLILQGN 396
Score = 37.4 bits (85), Expect = 0.057
Identities = 22/72 (30%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
Query: 100 LGQSSLQVLQLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLS 159
L +LQ +++ YN+L+ + S + L + HN+I + A P+L S+DLS
Sbjct: 94 LESQTLQEVKMNYNELTEIPY-FGEPTSNITLLSLVHNIIPEINAQALQFYPALESLDLS 152
Query: 160 SNRLSRLDGATF 171
SN +S + ++F
Sbjct: 153 SNIISEIKTSSF 164
Score = 32.7 bits (73), Expect = 1.4
Identities = 27/99 (27%), Positives = 42/99 (42%), Gaps = 13/99 (13%)
Query: 55 STVHDLRLNENKLKAVLYSSLNRFGNLTDLN---LTKNEISYIEDGAFLGQSSLQVLQLG 111
S + L L N++ + + F LT L L N+I I AF+G SL+ L L
Sbjct: 359 SNLQTLDLRNNEISWAIEDASEAFAGLTSLTKLILQGNQIKSITKKAFIGLESLEHLDLN 418
Query: 112 YNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSEC 150
N + ++ E F Q +L E++ T+ C
Sbjct: 419 NNAIMSIQEN----------AFSQTHLKELILNTSSLLC 447
>gi|4759146 slit homolog 2 [Homo sapiens]
Length = 1529
Score = 86.7 bits (213), Expect = 8e-17
Identities = 52/175 (29%), Positives = 87/175 (49%), Gaps = 5/175 (2%)
Query: 49 IPQHINSTVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVL 108
IP ++ T+ ++RL +N +K + + + + L ++L+ N+IS + AF G SL L
Sbjct: 294 IPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDAFQGLRSLNSL 353
Query: 109 QLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDG 168
L NK++ L + + G+ LQ L + N I + AF + +L + L N+L +
Sbjct: 354 VLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAK 413
Query: 169 ATFASLASLMVCELAGNPFNCECDLFGFLAWLVVFNNVTK-NYDRLQCESPREFA 222
TF+ L ++ LA NPF C+C L WL + + +C SPR A
Sbjct: 414 GTFSPLRAIQTMHLAQNPFICDC----HLKWLADYLHTNPIETSGARCTSPRRLA 464
Score = 85.1 bits (209), Expect = 2e-16
Identities = 50/153 (32%), Positives = 80/153 (52%), Gaps = 5/153 (3%)
Query: 49 IPQHINSTVHDLRLNENKLKAVLYSSL-NRFGNLTDLNLTKNEISYIEDGAFLGQSSLQV 107
IP+HI +LRLN N+ + + + + L +N + N+I+ IE+GAF G S +
Sbjct: 527 IPEHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNE 586
Query: 108 LQLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLD 167
+ L N+L N+ M +G+ L+ L ++ N I V +F S+ + L N+++ +
Sbjct: 587 ILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVA 646
Query: 168 GATFASLASLMVCELAGNPFNCECDLFGFLAWL 200
F +L SL L NPFNC C +LAWL
Sbjct: 647 PGAFDTLHSLSTLNLLANPFNCNC----YLAWL 675
Score = 61.2 bits (147), Expect = 4e-09
Identities = 38/141 (26%), Positives = 62/141 (43%)
Query: 60 LRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLSNLT 119
L+L ENK+ + + L L L +N + + FLG + L L L N++ +
Sbjct: 84 LQLMENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIP 143
Query: 120 EGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMV 179
RG ++ L + +N I + AF L + L++N ++RL A+F + L
Sbjct: 144 RKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRT 203
Query: 180 CELAGNPFNCECDLFGFLAWL 200
L N C+C L WL
Sbjct: 204 FRLHSNNLYCDCHLAWLSDWL 224
Score = 58.9 bits (141), Expect = 2e-08
Identities = 39/138 (28%), Positives = 65/138 (47%)
Query: 48 TIPQHINSTVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQV 107
++P++I L LN N + + + +L L L +N+IS IE GAF L+
Sbjct: 48 SVPRNIPRNTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELER 107
Query: 108 LQLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLD 167
L+L N L E + G ++L L + N I+ + AF + ++ L N++S ++
Sbjct: 108 LRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIE 167
Query: 168 GATFASLASLMVCELAGN 185
F +L L V L N
Sbjct: 168 DGAFRALRDLEVLTLNNN 185
Score = 51.6 bits (122), Expect = 3e-06
Identities = 40/163 (24%), Positives = 70/163 (42%), Gaps = 6/163 (3%)
Query: 65 NKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLSNLTEGMLR 124
NK VL + R ++T+L L N+ + + L ++ L N++S L+
Sbjct: 742 NKGLKVLPKGIPR--DVTELYLDGNQFTLVPK-ELSNYKHLTLIDLSNNRISTLSNQSFS 798
Query: 125 GMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMVCELAG 184
M++L L + +N + + P F SL + L N +S + F L++L +
Sbjct: 799 NMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGA 858
Query: 185 NPFNCECDLFGFLAWLVVFNNVTKNYDRLQCESPREFAGYPLL 227
NP C+C++ W+ + K +C P E A LL
Sbjct: 859 NPLYCDCNMQWLSDWV---KSEYKEPGIARCAGPGEMADKLLL 898
Score = 50.4 bits (119), Expect = 6e-06
Identities = 45/158 (28%), Positives = 64/158 (40%), Gaps = 4/158 (2%)
Query: 80 NLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLSNLTEGMLRGMSRLQFLFVQHNLI 139
N L+L N I+ I F G L+VLQL NK+S + G + + L+ L + N +
Sbjct: 56 NTERLDLNGNNITRITKTDFAGLRHLRVLQLMENKISTIERGAFQDLKELERLRLNRNHL 115
Query: 140 EVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMVCELAGNPFNC-ECDLFGFLA 198
++ F L +DLS N++ + F + +L N +C E F L
Sbjct: 116 QLFPELLFLGTAKLYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALR 175
Query: 199 WLVVFNNVTKNYDRLQCESPREFAGYPLLVPRPYHSLN 236
L V N RL S F P L HS N
Sbjct: 176 DLEVLTLNNNNITRLSVAS---FNHMPKLRTFRLHSNN 210
Score = 44.3 bits (103), Expect = 5e-04
Identities = 25/81 (30%), Positives = 44/81 (54%)
Query: 57 VHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLS 116
++ L L+EN+++A+ + ++ +L L N+IS IEDGAF L+VL L N ++
Sbjct: 129 LYRLDLSENQIQAIPRKAFRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNIT 188
Query: 117 NLTEGMLRGMSRLQFLFVQHN 137
L+ M +L+ + N
Sbjct: 189 RLSVASFNHMPKLRTFRLHSN 209
Score = 31.6 bits (70), Expect = 3.1
Identities = 19/56 (33%), Positives = 32/56 (57%)
Query: 60 LRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKL 115
L L+ N+L+ + + + +L L+L N+IS + +GAF S+L L +G N L
Sbjct: 806 LILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPL 861
>gi|229089140 leucine rich repeat containing 24 [Homo sapiens]
Length = 513
Score = 86.3 bits (212), Expect = 1e-16
Identities = 56/170 (32%), Positives = 83/170 (48%), Gaps = 2/170 (1%)
Query: 60 LRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLSNLT 119
L L+ N L+A+ + L +L LT N + + GAF+G + L+VL L N+L+ L
Sbjct: 79 LYLHNNSLRALEAGAFRAQPRLLELALTSNRLRGLRSGAFVGLAQLRVLYLAGNQLARLL 138
Query: 120 EGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMV 179
+ + RLQ L +Q N IE++ A + SL +DLS N+L + LASL V
Sbjct: 139 DFTFLHLPRLQELHLQENSIELLEDQALAGLSSLALLDLSRNQLGTISREALQPLASLQV 198
Query: 180 CELAGNPFNCECDLFGFLAWLVVFNN--VTKNYDRLQCESPREFAGYPLL 227
L NP+ C+C L AW+ +T ++ C P A LL
Sbjct: 199 LRLTENPWRCDCALHWLGAWIKEGGQRLLTSRDRKIMCAEPPRLALQSLL 248
>gi|239752702 PREDICTED: leucine rich repeat containing 38, partial
[Homo sapiens]
Length = 254
Score = 85.5 bits (210), Expect = 2e-16
Identities = 52/174 (29%), Positives = 82/174 (47%), Gaps = 1/174 (0%)
Query: 48 TIPQHINSTVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQV 107
++P V L + N+++ + +G+L L+ N + +E+G F G + L
Sbjct: 9 SVPDPFPLDVRKLLVAGNRIQRIPEDFFIFYGDLVYLDFRNNSLRSLEEGTFSGSAKLVF 68
Query: 108 LQLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLD 167
L L YN L+ L G R RL L + +N + V AF SL ++L+ N L L
Sbjct: 69 LDLSYNNLTQLGAGAFRSAGRLVKLSLANNNLVGVHEDAFETLESLQVLELNDNNLRSLS 128
Query: 168 GATFASLASLMVCELAGNPFNCECDLFGFLAWLVV-FNNVTKNYDRLQCESPRE 220
A A+L +L L GNP+ C+CD +W+ + + K D +QC P E
Sbjct: 129 VAALAALPALRSLRLDGNPWLCDCDFAHLFSWIQENASKLPKGLDEIQCSLPME 182
>gi|239747236 PREDICTED: leucine rich repeat containing 38 [Homo
sapiens]
Length = 408
Score = 85.5 bits (210), Expect = 2e-16
Identities = 52/174 (29%), Positives = 82/174 (47%), Gaps = 1/174 (0%)
Query: 48 TIPQHINSTVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQV 107
++P V L + N+++ + +G+L L+ N + +E+G F G + L
Sbjct: 163 SVPDPFPLDVRKLLVAGNRIQRIPEDFFIFYGDLVYLDFRNNSLRSLEEGTFSGSAKLVF 222
Query: 108 LQLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLD 167
L L YN L+ L G R RL L + +N + V AF SL ++L+ N L L
Sbjct: 223 LDLSYNNLTQLGAGAFRSAGRLVKLSLANNNLVGVHEDAFETLESLQVLELNDNNLRSLS 282
Query: 168 GATFASLASLMVCELAGNPFNCECDLFGFLAWLVV-FNNVTKNYDRLQCESPRE 220
A A+L +L L GNP+ C+CD +W+ + + K D +QC P E
Sbjct: 283 VAALAALPALRSLRLDGNPWLCDCDFAHLFSWIQENASKLPKGLDEIQCSLPME 336
>gi|239741057 PREDICTED: leucine rich repeat containing 38 [Homo
sapiens]
Length = 408
Score = 85.5 bits (210), Expect = 2e-16
Identities = 52/174 (29%), Positives = 82/174 (47%), Gaps = 1/174 (0%)
Query: 48 TIPQHINSTVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQV 107
++P V L + N+++ + +G+L L+ N + +E+G F G + L
Sbjct: 163 SVPDPFPLDVRKLLVAGNRIQRIPEDFFIFYGDLVYLDFRNNSLRSLEEGTFSGSAKLVF 222
Query: 108 LQLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLD 167
L L YN L+ L G R RL L + +N + V AF SL ++L+ N L L
Sbjct: 223 LDLSYNNLTQLGAGAFRSAGRLVKLSLANNNLVGVHEDAFETLESLQVLELNDNNLRSLS 282
Query: 168 GATFASLASLMVCELAGNPFNCECDLFGFLAWLVV-FNNVTKNYDRLQCESPRE 220
A A+L +L L GNP+ C+CD +W+ + + K D +QC P E
Sbjct: 283 VAALAALPALRSLRLDGNPWLCDCDFAHLFSWIQENASKLPKGLDEIQCSLPME 336
>gi|41582239 immunoglobulin superfamily containing leucine-rich
repeat [Homo sapiens]
Length = 428
Score = 85.5 bits (210), Expect = 2e-16
Identities = 79/311 (25%), Positives = 121/311 (38%), Gaps = 38/311 (12%)
Query: 9 AALLCVCRPGAVRADCWLIEGDKGYVWLAICSQNQPPYETIPQHINSTVHDLRLNENKLK 68
A LL + + DC G+K +A C+ E++P + V L L+ N+L
Sbjct: 10 ALLLGLAQACPEPCDC----GEKYGFQIADCAYRD--LESVPPGFPANVTTLSLSANRLP 63
Query: 69 AVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLSNLTEGMLRGMSR 128
+ + L L L NEI + GA S L+ L L +N +S+ L +S
Sbjct: 64 GLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLISDFAWSDLHNLSA 123
Query: 129 LQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMVCELAGNPFN 188
LQ L + N + + AF +L S+ L+ NRL L TF L +L ++ NPF+
Sbjct: 124 LQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSHLQINENPFD 183
Query: 189 CECDLFGFLAWLVVFNNVTKNYDRLQCESPREFAGYPLLVPRPYHSLNAITVLQAKCRNG 248
C C + W + D + C SP G PL
Sbjct: 184 CTCGIVWLKTWALTTAVSIPEQDNIACTSPHVLKGTPL---------------------S 222
Query: 249 SLPARPVSHPTPYSTDAQREPDENSG-FNPDEILSVEPPASSTTDASAGPAIKLH-HVTF 306
LP P S P S +P ++ P +L++ D PA +LH H+
Sbjct: 223 RLPPLPCSAP---SVQLSYQPSQDGAELRPGFVLALH------CDVDGQPAPQLHWHIQI 273
Query: 307 TSATLVVIIPH 317
S + + P+
Sbjct: 274 PSGIVEITSPN 284
>gi|5031809 immunoglobulin superfamily containing leucine-rich
repeat [Homo sapiens]
Length = 428
Score = 85.5 bits (210), Expect = 2e-16
Identities = 79/311 (25%), Positives = 121/311 (38%), Gaps = 38/311 (12%)
Query: 9 AALLCVCRPGAVRADCWLIEGDKGYVWLAICSQNQPPYETIPQHINSTVHDLRLNENKLK 68
A LL + + DC G+K +A C+ E++P + V L L+ N+L
Sbjct: 10 ALLLGLAQACPEPCDC----GEKYGFQIADCAYRD--LESVPPGFPANVTTLSLSANRLP 63
Query: 69 AVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLSNLTEGMLRGMSR 128
+ + L L L NEI + GA S L+ L L +N +S+ L +S
Sbjct: 64 GLPEGAFREVPLLQSLWLAHNEIRTVAAGALASLSHLKSLDLSHNLISDFAWSDLHNLSA 123
Query: 129 LQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMVCELAGNPFN 188
LQ L + N + + AF +L S+ L+ NRL L TF L +L ++ NPF+
Sbjct: 124 LQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNRLHTLAEGTFTPLTALSHLQINENPFD 183
Query: 189 CECDLFGFLAWLVVFNNVTKNYDRLQCESPREFAGYPLLVPRPYHSLNAITVLQAKCRNG 248
C C + W + D + C SP G PL
Sbjct: 184 CTCGIVWLKTWALTTAVSIPEQDNIACTSPHVLKGTPL---------------------S 222
Query: 249 SLPARPVSHPTPYSTDAQREPDENSG-FNPDEILSVEPPASSTTDASAGPAIKLH-HVTF 306
LP P S P S +P ++ P +L++ D PA +LH H+
Sbjct: 223 RLPPLPCSAP---SVQLSYQPSQDGAELRPGFVLALH------CDVDGQPAPQLHWHIQI 273
Query: 307 TSATLVVIIPH 317
S + + P+
Sbjct: 274 PSGIVEITSPN 284
>gi|4758460 glycoprotein V (platelet) [Homo sapiens]
Length = 560
Score = 85.1 bits (209), Expect = 2e-16
Identities = 53/171 (30%), Positives = 83/171 (48%), Gaps = 1/171 (0%)
Query: 57 VHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKN-EISYIEDGAFLGQSSLQVLQLGYNKL 115
+ +L LN +L+ + ++ L L +T + +S + GAF G LQVL L N L
Sbjct: 292 LQELWLNRTQLRTLPAAAFRNLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLALHSNGL 351
Query: 116 SNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLA 175
+ L +G+LRG+ +L+ + ++ N + + F SL S+ L N+L L G F +L
Sbjct: 352 TALPDGLLRGLGKLRQVSLRRNRLRALPRALFRNLSSLESVQLDHNQLETLPGDVFGALP 411
Query: 176 SLMVCELAGNPFNCECDLFGFLAWLVVFNNVTKNYDRLQCESPREFAGYPL 226
L L N + C+C L FL WL + + +C P AG PL
Sbjct: 412 RLTEVLLGHNSWRCDCGLGPFLGWLRQHLGLVGGEEPPRCAGPGAHAGLPL 462
Score = 65.9 bits (159), Expect = 1e-10
Identities = 42/130 (32%), Positives = 65/130 (50%)
Query: 57 VHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLS 116
+ +L LN+N+L + S NL L+L+ N ++++ G Q+ L+ L L N+L
Sbjct: 148 LQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTHLPKGLLGAQAKLERLLLHSNRLV 207
Query: 117 NLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLAS 176
+L G+L + L L N I + P AF P+L S+ LS N L+ L A F +
Sbjct: 208 SLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSRNHLAFLPSALFLHSHN 267
Query: 177 LMVCELAGNP 186
L + L NP
Sbjct: 268 LTLLTLFENP 277
Score = 54.7 bits (130), Expect = 3e-07
Identities = 31/105 (29%), Positives = 56/105 (53%)
Query: 81 LTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIE 140
L L ++ + IS + G F L+ L+L NK+++L +L M L+ LF+ HN +
Sbjct: 76 LQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLLEQLFLDHNALR 135
Query: 141 VVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMVCELAGN 185
+ F + +L + L+ N+L L + F +L +L + +L+GN
Sbjct: 136 GIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGN 180
Score = 45.4 bits (106), Expect = 2e-04
Identities = 35/118 (29%), Positives = 52/118 (44%)
Query: 60 LRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLSNLT 119
L L+ N+L ++ LN G LT+L +N I I GAF +L L L N L+ L
Sbjct: 199 LLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSRNHLAFLP 258
Query: 120 EGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASL 177
+ L L + N + + F E L + L+ +L L A F +L+ L
Sbjct: 259 SALFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLRTLPAAAFRNLSRL 316
Score = 33.1 bits (74), Expect = 1.1
Identities = 18/53 (33%), Positives = 28/53 (52%)
Query: 125 GMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASL 177
GM+ LQ L + + I V P FS+ L ++ LS N+++ L GA + L
Sbjct: 72 GMTVLQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLL 124
>gi|139948432 adlican [Homo sapiens]
Length = 2828
Score = 84.7 bits (208), Expect = 3e-16
Identities = 74/268 (27%), Positives = 112/268 (41%), Gaps = 53/268 (19%)
Query: 48 TIPQHINSTVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQV 107
++P I V + L N ++A+ +S L L + NEI I DGA SSLQV
Sbjct: 48 SVPAGIAKHVERINLGFNSIQALSETSFAGLTKLELLMIHGNEIPSIPDGALRDLSSLQV 107
Query: 108 LQLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLD 167
+ YNKL +T L+G+S L L + HN IE + P AF+ SL + L N L +L
Sbjct: 108 FKFSYNKLRVITGQTLQGLSNLMRLHIDHNKIEFIHPQAFNGLTSLRLLHLEGNLLHQLH 167
Query: 168 GATFAS----------------LASLMV----------------CELAGNPFNCECDLFG 195
+TF++ LA MV L GNP+ C+C++
Sbjct: 168 PSTFSTFTFLDYFRLSTIRHLYLAENMVRTLPASMLRNMPLLENLYLQGNPWTCDCEMRW 227
Query: 196 FLAWLVVFNNVTKNYDRLQCESPREFAGYPL---------LVPRPYHSLNAITVLQAKCR 246
FL W K+ L+C+ + + G L L H L +T L+
Sbjct: 228 FLEW------DAKSRGILKCKKDKAYEGGQLCAMCFSPKKLYKHEIHKLKDMTCLKPSIE 281
Query: 247 NGSLPARPVSHPTPYSTDAQREPDENSG 274
+ P+ S + ++E +E+ G
Sbjct: 282 S------PLRQNRSRSIEEEQEQEEDGG 303
>gi|40217825 slit and trk like 6 [Homo sapiens]
Length = 841
Score = 84.0 bits (206), Expect = 5e-16
Identities = 69/263 (26%), Positives = 114/263 (43%), Gaps = 17/263 (6%)
Query: 56 TVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKL 115
T+ L L N+++ + S L L L N ++ + G FLG +L+ L L YN +
Sbjct: 388 TLEMLHLGNNRIEVLEEGSFMNLTRLQKLYLNGNHLTKLSKGMFLGLHNLEYLYLEYNAI 447
Query: 116 SNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDGATFA-SL 174
+ G M +L+ L++ +NL++V+ P FS P L ++L +N+ + L + L
Sbjct: 448 KEILPGTFNPMPKLKVLYLNNNLLQVLPPHIFSGVP-LTKVNLKTNQFTHLPVSNILDDL 506
Query: 175 ASLMVCELAGNPFNCECDLFGFLAWLVVFNNVTKNYDRLQCESPREFAGYPLLVPRPYHS 234
L +L NP++C CDL G W+ + T D + C SP L + +
Sbjct: 507 DLLTQIDLEDNPWDCSCDLVGLQQWIQKLSKNTVT-DDILCTSPGH------LDKKELKA 559
Query: 235 LNAITVLQAKCRNGSLPARPVSHPTPYSTDAQREPDENSGFNPDEILSVEPPASSTTDAS 294
LN+ + N S+P + T Y N+ D IL A +
Sbjct: 560 LNSEILCPGLVNNPSMPTQ-----TSYLMVTTPATTTNTA---DTILRSLTDAVPLSVLI 611
Query: 295 AGPAIKLHHVTFTSATLVVIIPH 317
G I + F +A +VV++ H
Sbjct: 612 LGLLIMFITIVFCAAGIVVLVLH 634
Score = 61.2 bits (147), Expect = 4e-09
Identities = 46/165 (27%), Positives = 68/165 (41%), Gaps = 24/165 (14%)
Query: 60 LRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLSNLT 119
L L N L + + + N ++L N I+ IE GAF G L+ L + +N L L
Sbjct: 69 LSLLNNGLTMLHTNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEILK 128
Query: 120 EGMLRGMSRLQFLFVQHNLIEVVTPTAFSEC-----------------------PSLISI 156
E G+ L+FL +N I V+ P+AFS+ L +
Sbjct: 129 EDTFHGLENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRFVPLTHL 188
Query: 157 DLSSNRLSRLDGATFAS-LASLMVCELAGNPFNCECDLFGFLAWL 200
DL N+L L F + ++ +L N + C CDL WL
Sbjct: 189 DLRGNQLQTLPYVGFLEHIGRILDLQLEDNKWACNCDLLQLKTWL 233
>gi|15029530 leucine rich repeat containing 4 [Homo sapiens]
Length = 653
Score = 81.3 bits (199), Expect = 3e-15
Identities = 104/458 (22%), Positives = 184/458 (40%), Gaps = 86/458 (18%)
Query: 55 STVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTK-NEISYIEDGAFLGQSSLQVLQLGY- 112
S + +L L N ++++ + NR +L L+L + ++ YI +GAF G +L+ L LG
Sbjct: 147 SKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYLNLGMC 206
Query: 113 ---------------------NKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECP 151
N + G G+S L+ L+V ++ + ++ AF
Sbjct: 207 NIKDMPNLTPLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLA 266
Query: 152 SLISIDLSSNRLSRLDGATFASLASLMVCELAGNPFNCECDLFGFLAWLVVFNNVTKNYD 211
SL+ ++L+ N LS L F L L+ L NP+NC+CD+ +LAW + T +
Sbjct: 267 SLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHNPWNCDCDIL-WLAWWLREYIPTNSTC 325
Query: 212 RLQCESPREFAGYPLLVPRPYHSLNAITVLQAKCRNGSLPARPVSHPTPYSTDAQREPDE 271
+C +P G L + V QA + + P+ DA R+ +
Sbjct: 326 CGRCHAPMHMRGRYL-----------VEVDQASFQCSA----------PFIMDAPRDLNI 364
Query: 272 NSGFNPDEILSVEPPASST----------TDASAGPAIKL--------HHVTFT-----S 308
+ G E+ PP SS + AS P I + HV + +
Sbjct: 365 SEG-RMAELKCRTPPMSSVKWLLPNGTVLSHASRHPRISVLNDGTLNFSHVLLSDTGVYT 423
Query: 309 ATLVVIIPHPYSKMYILV---QYNNSYFSDVMTLK-NKKEIVTLDKLRAHTEYTFCVTSL 364
+ + + + Y+ V + N S +S T+ EI D R + T
Sbjct: 424 CMVTNVAGNSNASAYLNVSTAELNTSNYSFFTTVTVETTEISPEDTTRKYKPVPTTSTGY 483
Query: 365 RNSRRFNHTCLTFTTRDPVPGDLAPSTSTTTHYIMT-----------ILGCLFGMVIVLG 413
+ + + T L TTR VP +A + TT + T I+GC + ++
Sbjct: 484 QPAYTTSTTVLIQTTR--VPKQVAVPATDTTDKMQTSLDEVMKTTKIIIGCFVAVTLLAA 541
Query: 414 AVYYCLRKRRMQEEKQKSVNVKKTILEMRYGADVDAGS 451
A+ K R + +++ +V +T+ ++ D+ A +
Sbjct: 542 AMLIVFYKLRKRHQQRSTVTAARTVEIIQVDEDIPAAT 579
Score = 67.4 bits (163), Expect = 5e-11
Identities = 44/135 (32%), Positives = 69/135 (51%), Gaps = 1/135 (0%)
Query: 49 IPQHINSTVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVL 108
+PQ I S L L EN ++ + + +L L L +N I IE GAF G +SL L
Sbjct: 69 VPQGIPSNTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTL 128
Query: 109 QLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSS-NRLSRLD 167
+L N L+ + G +S+L+ L++++N IE + AF+ PSL+ +DL +L +
Sbjct: 129 ELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGELKKLEYIS 188
Query: 168 GATFASLASLMVCEL 182
F L +L L
Sbjct: 189 EGAFEGLFNLKYLNL 203
Score = 33.9 bits (76), Expect = 0.63
Identities = 28/107 (26%), Positives = 41/107 (38%), Gaps = 24/107 (22%)
Query: 80 NLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLSNLTEGMLRGMSRLQFLFVQHNLI 139
N LNL +N I I+ F L+VLQLG N + + G G++
Sbjct: 76 NTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLA------------ 123
Query: 140 EVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMVCELAGNP 186
SL +++L N L+ + F L+ L L NP
Sbjct: 124 ------------SLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNP 158
>gi|27436867 slit and trk like 4 protein [Homo sapiens]
Length = 837
Score = 80.9 bits (198), Expect = 4e-15
Identities = 68/245 (27%), Positives = 110/245 (44%), Gaps = 38/245 (15%)
Query: 47 ETIPQHINSTVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQ 106
E IP+ +N+ L +N N +K V S F L L+L N+I+ I+ F ++L+
Sbjct: 371 ELIPKPLNAK--KLHVNGNSIKDVDVSDFTDFEGLDLLHLGSNQITVIKGDVFHNLTNLR 428
Query: 107 VLQLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRL 166
L L N++ L + G+ LQ+L++++NLI+ ++ F P+L + L++N L L
Sbjct: 429 RLYLNGNQIERLYPEIFSGLHNLQYLYLEYNLIKEISAGTFDSMPNLQLLYLNNNLLKSL 488
Query: 167 -----DGATFA-------------------SLASLMVCELAGNPFNCECDLFGFLAWLVV 202
GA A L SL +L GNP++C CDL W+
Sbjct: 489 PVYIFSGAPLARLNLRNNKFMYLPVSGVLDQLQSLTQIDLEGNPWDCTCDLVALKLWVEK 548
Query: 203 FNN--VTKNYDRLQCESPREFAGYPL-------LVPRPYHSLNAITVLQAKCRNGSLPAR 253
++ V K L+CE+P +FA L L P+ + +A A + P
Sbjct: 549 LSDGIVVK---ELKCETPVQFANIELKSLKNEILCPKLLNKPSAPFTSPAPAITFTTPLG 605
Query: 254 PVSHP 258
P+ P
Sbjct: 606 PIRSP 610
Score = 72.8 bits (177), Expect = 1e-12
Identities = 56/210 (26%), Positives = 90/210 (42%), Gaps = 37/210 (17%)
Query: 40 SQNQPPYETIPQHINSTVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAF 99
+Q +PP+ S + L N L + ++ F + L+L N++ IE GAF
Sbjct: 52 NQLKPPW--------SNFYHLNFQNNFLNILYPNTFLNFSHAVSLHLGNNKLQNIEGGAF 103
Query: 100 LGQSSLQVLQLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSEC--------- 150
LG S+L+ L L N+L L G+ L++L +NLI+ + AF++
Sbjct: 104 LGLSALKQLHLNNNELKILRADTFLGIENLEYLQADYNLIKYIERGAFNKLHKLKVLILN 163
Query: 151 --------------PSLISIDLSSNRLSRLDG-ATFASLASLMVCELAGNPFNCECDLFG 195
SL +D+ NR+ +L + ++ +L NP+NC CDL
Sbjct: 164 DNLISFLPDNIFRFASLTHLDIRGNRIQKLPYIGVLEHIGRVVELQLEDNPWNCSCDLLP 223
Query: 196 FLAWLVVFNNVTKN--YDRLQCESPREFAG 223
AWL N+ N CE+P + G
Sbjct: 224 LKAWL---ENMPYNIYIGEAICETPSDLYG 250
>gi|12597641 leucine rich repeat containing 19 [Homo sapiens]
Length = 370
Score = 80.5 bits (197), Expect = 6e-15
Identities = 54/188 (28%), Positives = 86/188 (45%), Gaps = 5/188 (2%)
Query: 39 CSQNQPPYETIPQHINS--TVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIED 96
C+ + Y IP I T+ DL N+ L L + LT+L L +N+++ + +
Sbjct: 31 CNFTEKNYTLIPADIKKDVTILDLSYNQITLNGTDTRVLQTYFLLTELYLIENKVTILHN 90
Query: 97 GAFLGQSSLQVLQLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISI 156
F SSL++L + N + + +G G+++L+ L++ N IE + F SL +
Sbjct: 91 NGFGNLSSLEILNICRNSIYVIQQGAFLGLNKLKQLYLCQNKIEQLNADVFVPLRSLKLL 150
Query: 157 DLSSNRLSRLDGATFASLASLMVCELAGNPFNCECDLFGFLAWLVVFNNVTKNYDRLQCE 216
+L N +S LD L L + L GN +NC C LF WL N +N + C
Sbjct: 151 NLQGNLISYLD---VPPLFHLELITLYGNLWNCSCSLFNLQNWLNTSNVTLENENITMCS 207
Query: 217 SPREFAGY 224
P Y
Sbjct: 208 YPNSLQSY 215
>gi|10190722 leucine-rich repeats and transmembrane domains 1 [Homo
sapiens]
Length = 345
Score = 80.5 bits (197), Expect = 6e-15
Identities = 77/290 (26%), Positives = 113/290 (38%), Gaps = 46/290 (15%)
Query: 6 LCAAALLCVCRPGAVRADCWLIEGDKGYVWLAICSQNQPPYETIPQHINSTVHDLRLNEN 65
+C+ C C+ DC +Q IP H+ L L +N
Sbjct: 18 VCSCPDKCYCQSSTNFVDC-----------------SQQGLAEIPSHLPPQTRTLHLQDN 60
Query: 66 KLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLSNLTEGMLRG 125
++ + + L LNL+ N +S + GAF G LQVL L N L +L +
Sbjct: 61 QIHHLPAFAFRSVPWLMTLNLSNNSLSNLAPGAFHGLQHLQVLNLTQNSLLSLESRLFHS 120
Query: 126 MSRLQFLFVQHNLIEVVTPTAFSEC-PSLISIDLSSNRLSRLDGATFASLASLMVCELAG 184
+ +L+ L + N I + PT+ E +L + + N+L +LD A S+ S+ + L
Sbjct: 121 LPQLRELDLSSNNISHL-PTSLGETWENLTILAVQQNQLQQLDRALLESMPSVRLLLLKD 179
Query: 185 NPFNCECDLFGFLAWLVVFNNVTKNYDRLQCESPREFAGYPLL-VPRPYHSLNAITVLQA 243
N + C C L G WL F D + CESP + G LL +P L
Sbjct: 180 NLWKCNCHLLGLKLWLEKFVYKGGLTDGIICESPDTWKGKDLLRIPHE---------LYQ 230
Query: 244 KCRNGSLPARPVSHPTPYSTDAQ---------REPDENSGFNPDEILSVE 284
C P+ P P S+ AQ P EN E+L E
Sbjct: 231 PC--------PLPAPDPVSSQAQWPGSAHGVVLRPPENHNAGERELLECE 272
>gi|126517478 peroxidasin homolog-like [Homo sapiens]
Length = 1463
Score = 80.1 bits (196), Expect = 8e-15
Identities = 58/212 (27%), Positives = 96/212 (45%), Gaps = 13/212 (6%)
Query: 49 IPQHINSTVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVL 108
+PQ +TV DLR N +++ + S+ + NL L L N I I AF G +L L
Sbjct: 48 VPQQ--TTVLDLRFN--RIREIPGSAFKKLKNLNTLLLNNNHIRKISRNAFEGLENLLYL 103
Query: 109 QLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDG 168
L N++ L + +G+ L+ L++ N +E++ P F + L + L +N+LS++
Sbjct: 104 YLYKNEIHALDKQTFKGLISLEHLYIHFNQLEMLQPETFGDLLRLERLFLHNNKLSKIPA 163
Query: 169 ATFASLASLMVCELAGNPFNCECDLFGFLAWLVVFNNVTKNYDRLQCESPREFAGYPLLV 228
+F++L SL L N C+CDL L F CE PR G
Sbjct: 164 GSFSNLDSLKRLRLDSNALVCDCDLMWLGELLQGFAQHGHTQAAATCEYPRRLHG----- 218
Query: 229 PRPYHSLNAITVLQAKCRNGSLPARPVSHPTP 260
++ ++TV + C++ + P P
Sbjct: 219 ----RAVASVTVEEFNCQSPRITFEPQDVEVP 246
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 79.7 bits (195), Expect = 1e-14
Identities = 52/200 (26%), Positives = 89/200 (44%), Gaps = 11/200 (5%)
Query: 55 STVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNK 114
+++ DLR N +++ + + R NL L L N+I I GAF +L+ L L N+
Sbjct: 64 TSILDLRFN--RIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYLYKNE 121
Query: 115 LSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDGATFASL 174
+ ++ +G++ L+ L++ N IE + P +F P L + L +NR++ L TF L
Sbjct: 122 IQSIDRQAFKGLASLEQLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHL 181
Query: 175 ASLMVCELAGNPFNCECDLFGFLAWLVVFNNVTKNYDRLQCESPREFAGYPLLVPRPYHS 234
S+ L N +C+C++ L + CE PR G S
Sbjct: 182 ESMKRLRLDSNTLHCDCEILWLADLLKTYAESGNAQAAAICEYPRRIQG---------RS 232
Query: 235 LNAITVLQAKCRNGSLPARP 254
+ IT + C + + P
Sbjct: 233 VATITPEELNCERPRITSEP 252
>gi|205277468 leucine rich repeat containing 15 isoform a [Homo
sapiens]
Length = 587
Score = 79.3 bits (194), Expect = 1e-14
Identities = 63/237 (26%), Positives = 106/237 (44%), Gaps = 15/237 (6%)
Query: 57 VHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLS 116
+ +L L +N + ++ + + L L L++N+IS+I GAF G + L+ L L N L
Sbjct: 301 LRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNALQ 360
Query: 117 NLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLAS 176
+L + R ++ LQ + +Q+N + + F+ L++I L +N+L L F L
Sbjct: 361 DLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLENLPLGIFDHLGK 420
Query: 177 LMVCELAGNPFNCECDLFGFLAWLVVFNNVTKNYDRLQ-CESPREFAGYPLLVPRPYHSL 235
L L NP+ C+ D+ WL++ N D + C SP G L++ ++
Sbjct: 421 LCELRLYDNPWRCDSDILPLRNWLLL-NQPRLGTDTVPVCFSPANVRGQSLIIINVNVAV 479
Query: 236 NAITVLQAKCRNGSLPARPVSHPTPYSTDAQREPDENSGFNPDEILSVEPPASSTTD 292
++ V P P TP+ D PD S + E+ S P TD
Sbjct: 480 PSVHV----------PEVPSYPETPWYPDTPSYPDTTSVSSTTELTS---PVEDYTD 523
Score = 68.6 bits (166), Expect = 2e-11
Identities = 45/138 (32%), Positives = 74/138 (53%), Gaps = 2/138 (1%)
Query: 50 PQHIN--STVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQV 107
P H + S + +L+L+ N L+ + + + LT LNL KN +++I F +LQV
Sbjct: 148 PAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGNLQV 207
Query: 108 LQLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLD 167
L+L N+L+++ G G+ LQ L +Q N I +++P F +L + LS+N +S+L
Sbjct: 208 LRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQLP 267
Query: 168 GATFASLASLMVCELAGN 185
+ F L L L GN
Sbjct: 268 PSIFMQLPQLNRLTLFGN 285
Score = 61.6 bits (148), Expect = 3e-09
Identities = 36/105 (34%), Positives = 50/105 (47%)
Query: 81 LTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIE 140
L L + KNE+S I GAF SL+ L L NKL L G+ +G+ L+ L + N +
Sbjct: 85 LIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLL 144
Query: 141 VVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMVCELAGN 185
+ P FS+C +L + L N L + F L L L N
Sbjct: 145 QIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKN 189
Score = 58.2 bits (139), Expect = 3e-08
Identities = 42/142 (29%), Positives = 69/142 (48%), Gaps = 2/142 (1%)
Query: 80 NLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLSNLTEGMLRGMSRLQFLFVQHNLI 139
N L + I+ + + FL S+L L++ N+LS +T G R + L++L + +N +
Sbjct: 60 NAMSLQILNTHITELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKL 119
Query: 140 EVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMVCELAGNPFNCECDLFGFLAW 199
+V+ F SL S+ LSSN+L ++ A F+ ++L +L GN D G
Sbjct: 120 QVLPIGLFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPD--GAFDH 177
Query: 200 LVVFNNVTKNYDRLQCESPREF 221
LV + + L SPR F
Sbjct: 178 LVGLTKLNLGKNSLTHISPRVF 199
Score = 57.4 bits (137), Expect = 5e-08
Identities = 40/148 (27%), Positives = 65/148 (43%), Gaps = 5/148 (3%)
Query: 38 ICSQNQPPYETIPQHINSTVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDG 97
I N+ P+ I S + LR+ +N+L + + G+L L+L N++ + G
Sbjct: 71 ITELNESPFLNI-----SALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKLQVLPIG 125
Query: 98 AFLGQSSLQVLQLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISID 157
F G SL+ L L N+L + S L+ L + N +E + AF L ++
Sbjct: 126 LFQGLDSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLN 185
Query: 158 LSSNRLSRLDGATFASLASLMVCELAGN 185
L N L+ + F L +L V L N
Sbjct: 186 LGKNSLTHISPRVFQHLGNLQVLRLYEN 213
Score = 56.6 bits (135), Expect = 9e-08
Identities = 36/118 (30%), Positives = 55/118 (46%)
Query: 60 LRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLSNLT 119
L L +N L + GNL L L +N ++ I G F G +LQ L L N++ L+
Sbjct: 184 LNLGKNSLTHISPRVFQHLGNLQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLS 243
Query: 120 EGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASL 177
G+ LQ L++ +N I + P+ F + P L + L N L L F + +L
Sbjct: 244 PGLFHNNHNLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNL 301
Score = 55.5 bits (132), Expect = 2e-07
Identities = 39/135 (28%), Positives = 66/135 (48%), Gaps = 1/135 (0%)
Query: 51 QHINSTVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQL 110
QH+ + + LRL EN+L + + + NL +L L +N+I + G F +LQ L L
Sbjct: 200 QHLGN-LQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYL 258
Query: 111 GYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDGAT 170
N +S L + + +L L + N ++ ++ F P+L + L N +S L
Sbjct: 259 SNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNLRELWLYDNHISSLPDNV 318
Query: 171 FASLASLMVCELAGN 185
F++L L V L+ N
Sbjct: 319 FSNLRQLQVLILSRN 333
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,507,468
Number of Sequences: 37866
Number of extensions: 1642085
Number of successful extensions: 10162
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 188
Number of HSP's successfully gapped in prelim test: 127
Number of HSP's that attempted gapping in prelim test: 8497
Number of HSP's gapped (non-prelim): 1118
length of query: 820
length of database: 18,247,518
effective HSP length: 111
effective length of query: 709
effective length of database: 14,044,392
effective search space: 9957473928
effective search space used: 9957473928
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.