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Search of human proteins with 238908501
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|238908501 sciellin isoform 3 [Homo sapiens]
(646 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|238908501 sciellin isoform 3 [Homo sapiens] 1295 0.0
gi|238908499 sciellin isoform 1 [Homo sapiens] 1270 0.0
gi|238908497 sciellin isoform 2 [Homo sapiens] 1219 0.0
gi|148298722 zinc finger protein 185 [Homo sapiens] 70 5e-12
gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens] 58 3e-08
gi|163310741 LIM and calponin homology domains 1 isoform a [Homo... 56 1e-07
gi|163310749 LIM and calponin homology domains 1 isoform e [Homo... 55 3e-07
gi|163310747 LIM and calponin homology domains 1 isoform d [Homo... 55 3e-07
gi|163310745 LIM and calponin homology domains 1 isoform c [Homo... 55 3e-07
gi|163310743 LIM and calponin homology domains 1 isoform b [Homo... 55 3e-07
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 44 4e-04
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 44 4e-04
gi|34303932 transmembrane and coiled-coil domains 5A [Homo sapiens] 42 0.002
gi|239757861 PREDICTED: similar to armadillo repeat containing, ... 41 0.003
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 39 0.011
gi|67551265 transcription factor ELYS [Homo sapiens] 39 0.011
gi|38373673 synaptonemal complex protein 2 [Homo sapiens] 39 0.011
gi|14249338 BUD13 homolog isoform 1 [Homo sapiens] 39 0.015
gi|115334679 retinoblastoma-binding protein 1 isoform III [Homo ... 39 0.019
gi|115334673 retinoblastoma-binding protein 1 isoform II [Homo s... 39 0.019
gi|115334677 retinoblastoma-binding protein 1 isoform I [Homo sa... 39 0.019
gi|228480221 four and a half LIM domains 1 isoform 4 [Homo sapiens] 38 0.025
gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens] 38 0.025
gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens] 38 0.025
gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens] 38 0.025
gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens] 38 0.025
gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens] 38 0.025
gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens] 38 0.025
gi|55770895 ERBB2 interacting protein isoform 7 [Homo sapiens] 38 0.033
gi|8923909 ERBB2 interacting protein isoform 2 [Homo sapiens] 38 0.033
>gi|238908501 sciellin isoform 3 [Homo sapiens]
Length = 646
Score = 1295 bits (3350), Expect = 0.0
Identities = 646/646 (100%), Positives = 646/646 (100%)
Query: 1 MSNVTLRKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGR 60
MSNVTLRKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGR
Sbjct: 1 MSNVTLRKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGR 60
Query: 61 VVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNR 120
VVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNR
Sbjct: 61 VVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNR 120
Query: 121 SMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKKREPGVHPPIPPKPSSPVSSPN 180
SMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKKREPGVHPPIPPKPSSPVSSPN
Sbjct: 121 SMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKKREPGVHPPIPPKPSSPVSSPN 180
Query: 181 QLRQDNRQIHPPKPGVYTETNRSAERNIRSQDLDNIVKVATSLQRSDKGEELDNLIKMNK 240
QLRQDNRQIHPPKPGVYTETNRSAERNIRSQDLDNIVKVATSLQRSDKGEELDNLIKMNK
Sbjct: 181 QLRQDNRQIHPPKPGVYTETNRSAERNIRSQDLDNIVKVATSLQRSDKGEELDNLIKMNK 240
Query: 241 SLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRTDKDGKGIQSLGSPIKVNQRTDK 300
SLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRTDKDGKGIQSLGSPIKVNQRTDK
Sbjct: 241 SLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRTDKDGKGIQSLGSPIKVNQRTDK 300
Query: 301 NEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKGHENTTGGQSLDNLIKVTPEVKR 360
NEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKGHENTTGGQSLDNLIKVTPEVKR
Sbjct: 301 NEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKGHENTTGGQSLDNLIKVTPEVKR 360
Query: 361 SNQGSKDLNNFIKVYPGTEKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANK 420
SNQGSKDLNNFIKVYPGTEKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANK
Sbjct: 361 SNQGSKDLNNFIKVYPGTEKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANK 420
Query: 421 SSEQGLDEHINVSPKAVKNTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNN 480
SSEQGLDEHINVSPKAVKNTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNN
Sbjct: 421 SSEQGLDEHINVSPKAVKNTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNN 480
Query: 481 QSQDLDNLIKVKPSALRNTNRDQNLENLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTR 540
QSQDLDNLIKVKPSALRNTNRDQNLENLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTR
Sbjct: 481 QSQDLDNLIKVKPSALRNTNRDQNLENLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTR 540
Query: 541 TYVENSKSPKDGYQENISGKYIQTVYSTSDRSVIERDMCTYCRKPLGVETKMILDELQIC 600
TYVENSKSPKDGYQENISGKYIQTVYSTSDRSVIERDMCTYCRKPLGVETKMILDELQIC
Sbjct: 541 TYVENSKSPKDGYQENISGKYIQTVYSTSDRSVIERDMCTYCRKPLGVETKMILDELQIC 600
Query: 601 CHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSKIMAKWIP 646
CHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSKIMAKWIP
Sbjct: 601 CHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSKIMAKWIP 646
>gi|238908499 sciellin isoform 1 [Homo sapiens]
Length = 688
Score = 1270 bits (3286), Expect = 0.0
Identities = 646/688 (93%), Positives = 646/688 (93%), Gaps = 42/688 (6%)
Query: 1 MSNVTLRKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGR 60
MSNVTLRKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGR
Sbjct: 1 MSNVTLRKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGR 60
Query: 61 VVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNR 120
VVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNR
Sbjct: 61 VVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNR 120
Query: 121 SMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKKR-------------------- 160
SMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKKR
Sbjct: 121 SMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKKRQSWFPPPPPGYNASSSTGTR 180
Query: 161 --EPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNIRSQDLDNIVK 218
EPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNIRSQDLDNIVK
Sbjct: 181 RREPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNIRSQDLDNIVK 240
Query: 219 VATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRT 278
VATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRT
Sbjct: 241 VATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRT 300
Query: 279 DKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKG 338
DKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKG
Sbjct: 301 DKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKG 360
Query: 339 HENTTG--------------------GQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGT 378
HENTTG GQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGT
Sbjct: 361 HENTTGKKDLDGLIKVDPETNKNITRGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGT 420
Query: 379 EKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVK 438
EKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVK
Sbjct: 421 EKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVK 480
Query: 439 NTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRN 498
NTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRN
Sbjct: 481 NTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRN 540
Query: 499 TNRDQNLENLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENIS 558
TNRDQNLENLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENIS
Sbjct: 541 TNRDQNLENLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENIS 600
Query: 559 GKYIQTVYSTSDRSVIERDMCTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENL 618
GKYIQTVYSTSDRSVIERDMCTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENL
Sbjct: 601 GKYIQTVYSTSDRSVIERDMCTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENL 660
Query: 619 QAGDSIWIYRQTIHCEPCYSKIMAKWIP 646
QAGDSIWIYRQTIHCEPCYSKIMAKWIP
Sbjct: 661 QAGDSIWIYRQTIHCEPCYSKIMAKWIP 688
>gi|238908497 sciellin isoform 2 [Homo sapiens]
Length = 668
Score = 1219 bits (3154), Expect = 0.0
Identities = 625/688 (90%), Positives = 625/688 (90%), Gaps = 62/688 (9%)
Query: 1 MSNVTLRKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGR 60
MSNVTLRKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGR
Sbjct: 1 MSNVTLRKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGR 60
Query: 61 VVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNR 120
VVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNR
Sbjct: 61 VVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNR 120
Query: 121 SMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKKR-------------------- 160
SMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKKR
Sbjct: 121 SMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKKRQSWFPPPPPGYNASSSTGTR 180
Query: 161 --EPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNIRSQDLDNIVK 218
EPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNI
Sbjct: 181 RREPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNI---------- 230
Query: 219 VATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRT 278
EELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRT
Sbjct: 231 ----------SEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRT 280
Query: 279 DKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKG 338
DKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKG
Sbjct: 281 DKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKG 340
Query: 339 HENTTG--------------------GQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGT 378
HENTTG GQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGT
Sbjct: 341 HENTTGKKDLDGLIKVDPETNKNITRGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGT 400
Query: 379 EKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVK 438
EKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVK
Sbjct: 401 EKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVK 460
Query: 439 NTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRN 498
NTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRN
Sbjct: 461 NTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRN 520
Query: 499 TNRDQNLENLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENIS 558
TNRDQNLENLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENIS
Sbjct: 521 TNRDQNLENLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENIS 580
Query: 559 GKYIQTVYSTSDRSVIERDMCTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENL 618
GKYIQTVYSTSDRSVIERDMCTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENL
Sbjct: 581 GKYIQTVYSTSDRSVIERDMCTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENL 640
Query: 619 QAGDSIWIYRQTIHCEPCYSKIMAKWIP 646
QAGDSIWIYRQTIHCEPCYSKIMAKWIP
Sbjct: 641 QAGDSIWIYRQTIHCEPCYSKIMAKWIP 668
>gi|148298722 zinc finger protein 185 [Homo sapiens]
Length = 689
Score = 70.5 bits (171), Expect = 5e-12
Identities = 30/63 (47%), Positives = 41/63 (65%), Gaps = 2/63 (3%)
Query: 578 MCTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCY 637
+CTYC + + K+ L+ L ICCH CFKC IC +P+ +L D I+I+R TIHC CY
Sbjct: 628 ICTYCNREIRDCPKITLEHLGICCHEYCFKCGICSKPMGDLL--DQIFIHRDTIHCGKCY 685
Query: 638 SKI 640
K+
Sbjct: 686 EKL 688
>gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens]
Length = 1349
Score = 57.8 bits (138), Expect = 3e-08
Identities = 36/119 (30%), Positives = 55/119 (46%), Gaps = 6/119 (5%)
Query: 519 KNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENISGKYIQTVYSTSDRSVIERDM 578
+N SS+ AG T + T V ++SP + S Q+ +RSV + +
Sbjct: 1226 RNPSSSVPPPSAGSVKT---STTGVATTQSPTP---RSHSPSASQSGSQLRNRSVSGKRI 1279
Query: 579 CTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCY 637
C+YC LG MI++ L +C H CFKC C+ L +G + I ++C CY
Sbjct: 1280 CSYCNNILGKGAAMIIESLGLCYHLHCFKCVACECDLGGSSSGAEVRIRNHQLYCNDCY 1338
Score = 29.6 bits (65), Expect = 9.0
Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 9/68 (13%)
Query: 7 RKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGRV-VLNR 65
++ P+G E++ +QQ E+ KR DNSWI++R E ++ R
Sbjct: 1122 KEQVPSGAELE--------RQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRR 1173
Query: 66 HNSHDALD 73
S D LD
Sbjct: 1174 GESLDNLD 1181
>gi|163310741 LIM and calponin homology domains 1 isoform a [Homo
sapiens]
Length = 1083
Score = 55.8 bits (133), Expect = 1e-07
Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 1/94 (1%)
Query: 547 KSPKDGYQENISGKYIQTVYSTS-DRSVIERDMCTYCRKPLGVETKMILDELQICCHSTC 605
KSP++ +Q T S +RS+ + +C+ C PLG MI++ L + H C
Sbjct: 980 KSPREHFQAGPFSPCSPTPPGQSPNRSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQC 1039
Query: 606 FKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSK 639
F+C ICK L + +G + I ++C CY +
Sbjct: 1040 FRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMR 1073
>gi|163310749 LIM and calponin homology domains 1 isoform e [Homo
sapiens]
Length = 890
Score = 54.7 bits (130), Expect = 3e-07
Identities = 43/177 (24%), Positives = 75/177 (42%), Gaps = 24/177 (13%)
Query: 481 QSQDLDNLIKVKPSALRNTNRDQNLENLIE---------VNSHVSENKNGSSNTGAKQAG 531
Q D D L+K R ++R + +L E V+ V E+ + GA G
Sbjct: 710 QGDDSDLLLKT-----RESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCG 764
Query: 532 PQDTVVYTRTYVENSKSPKDGYQENISGKYI-------QTVYSTSDR--SVIERDMCTYC 582
+ + + + +P E++ K + + S S+R S+ + +C+ C
Sbjct: 765 TNPQLAQDPSQNQQTSNPTHS-SEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSC 823
Query: 583 RKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSK 639
PLG MI++ L + H CF+C ICK L + +G + I ++C CY +
Sbjct: 824 GLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMR 880
>gi|163310747 LIM and calponin homology domains 1 isoform d [Homo
sapiens]
Length = 902
Score = 54.7 bits (130), Expect = 3e-07
Identities = 43/177 (24%), Positives = 75/177 (42%), Gaps = 24/177 (13%)
Query: 481 QSQDLDNLIKVKPSALRNTNRDQNLENLIE---------VNSHVSENKNGSSNTGAKQAG 531
Q D D L+K R ++R + +L E V+ V E+ + GA G
Sbjct: 722 QGDDSDLLLKT-----RESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCG 776
Query: 532 PQDTVVYTRTYVENSKSPKDGYQENISGKYI-------QTVYSTSDR--SVIERDMCTYC 582
+ + + + +P E++ K + + S S+R S+ + +C+ C
Sbjct: 777 TNPQLAQDPSQNQQTSNPTHS-SEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSC 835
Query: 583 RKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSK 639
PLG MI++ L + H CF+C ICK L + +G + I ++C CY +
Sbjct: 836 GLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMR 892
>gi|163310745 LIM and calponin homology domains 1 isoform c [Homo
sapiens]
Length = 1056
Score = 54.7 bits (130), Expect = 3e-07
Identities = 43/177 (24%), Positives = 75/177 (42%), Gaps = 24/177 (13%)
Query: 481 QSQDLDNLIKVKPSALRNTNRDQNLENLIE---------VNSHVSENKNGSSNTGAKQAG 531
Q D D L+K R ++R + +L E V+ V E+ + GA G
Sbjct: 876 QGDDSDLLLKT-----RESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCG 930
Query: 532 PQDTVVYTRTYVENSKSPKDGYQENISGKYI-------QTVYSTSDR--SVIERDMCTYC 582
+ + + + +P E++ K + + S S+R S+ + +C+ C
Sbjct: 931 TNPQLAQDPSQNQQTSNPTHS-SEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSC 989
Query: 583 RKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSK 639
PLG MI++ L + H CF+C ICK L + +G + I ++C CY +
Sbjct: 990 GLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMR 1046
>gi|163310743 LIM and calponin homology domains 1 isoform b [Homo
sapiens]
Length = 1057
Score = 54.7 bits (130), Expect = 3e-07
Identities = 43/177 (24%), Positives = 75/177 (42%), Gaps = 24/177 (13%)
Query: 481 QSQDLDNLIKVKPSALRNTNRDQNLENLIE---------VNSHVSENKNGSSNTGAKQAG 531
Q D D L+K R ++R + +L E V+ V E+ + GA G
Sbjct: 877 QGDDSDLLLKT-----RESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCG 931
Query: 532 PQDTVVYTRTYVENSKSPKDGYQENISGKYI-------QTVYSTSDR--SVIERDMCTYC 582
+ + + + +P E++ K + + S S+R S+ + +C+ C
Sbjct: 932 TNPQLAQDPSQNQQTSNPTHS-SEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSC 990
Query: 583 RKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSK 639
PLG MI++ L + H CF+C ICK L + +G + I ++C CY +
Sbjct: 991 GLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMR 1047
>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
Length = 1758
Score = 44.3 bits (103), Expect = 4e-04
Identities = 77/422 (18%), Positives = 163/422 (38%), Gaps = 54/422 (12%)
Query: 157 KKKREPGVHPPIP------PKPSSPVSSPNQLRQDN-----RQIHPPKPGVYTETNRSAE 205
+++R P PPI PK + SS + + + R+ H + ET E
Sbjct: 1014 ERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKE 1073
Query: 206 RNIR---SQDLDN---IVKVATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANP--- 256
++ S+D+ + K + + ++K + LDN + K +G+D F ++
Sbjct: 1074 EKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKI 1133
Query: 257 -KVEERE-----KRAKSLESLIYMSTRTDKDGKGIQSLGSPIKVNQRTDKNEKGRQNLES 310
K+E E + K M +KD + + IK+N+ T K +N+ +
Sbjct: 1134 SKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISN 1193
Query: 311 VAKVNARMNKTSRRSEDLDNATEVNPKGHENTTGGQ-SLDNLIKVT-------PEVKRSN 362
+ + ++ TS + + +V K TG + S L+ T V++S
Sbjct: 1194 TKEPSEKLESTSSKVKQ----EKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSE 1249
Query: 363 QGSKDLNNFIKVYPG-TEKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANKS 421
+ + IK +T + + +I+V + + + E++ P ++
Sbjct: 1250 EKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVG 1309
Query: 422 SEQGLDEHINVSPKAV-----KNTDGKQDLDKLIK-VNPEIFTNNQRNQDLANLIKVNPA 475
+ ++++ P + K ++ + + K K V+ EI + ++ N A
Sbjct: 1310 KPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSK-------NSA 1362
Query: 476 VIRNNQSQDLDN--LIKVKPSALRNTNRDQNLENLIEVNSHVSENKNGSSNTGAKQAGPQ 533
+++D D L K P +N+ + + NL +N + S+ A+ +
Sbjct: 1363 SSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKH 1422
Query: 534 DT 535
D+
Sbjct: 1423 DS 1424
Score = 37.7 bits (86), Expect = 0.033
Identities = 102/570 (17%), Positives = 196/570 (34%), Gaps = 59/570 (10%)
Query: 7 RKMSPTGNEMKSTTQ------GTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGR 60
RKM P +M T + K+ + ++ +N K P E+ + +
Sbjct: 1148 RKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSK 1207
Query: 61 VVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTL------- 113
V + + RKV + +T+ Y+S + R KT T+
Sbjct: 1208 V--KQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEY 1265
Query: 114 DNQLTNRSMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKK--------KREPGVH 165
+N T + + ++V + + + + ST + V K +P
Sbjct: 1266 NNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNI 1325
Query: 166 PPIPPKPSSPVSSPNQLRQD------NRQIHPPKPGVYTETNRSAERNIRSQDLDNIVKV 219
P K S P + +D ++ K +E ++ +R+ + +N K
Sbjct: 1326 VKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKR 1385
Query: 220 ATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLI-YMSTRT 278
S Q E+ NL ++N+ N S A + RA S + +T
Sbjct: 1386 KNSTQP----EKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKT 1441
Query: 279 DKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKG 338
D D + S + N+ T + + +N +S + + NK R DL + K
Sbjct: 1442 DYDTREYSSSKRRDEKNELTRRKDSPSRNKDSAS---GQKNKP-REERDLPKKGTGDSKK 1497
Query: 339 HENTTGGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGTEKSTEGGQSLDSLIKVTPER 398
++ + K T + KR N+ +K ++ P ++ +
Sbjct: 1498 SNSSPSRDRKPHDHKATYDTKRPNEETKSVDK----NPCKDREKH---------VLEARN 1544
Query: 399 NRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVKNTDGKQDLDKLIKVNPEIFT 458
N+ + GN+ L L K G + V PK + + D + + F
Sbjct: 1545 NKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFE 1604
Query: 459 NNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRNTNRDQNLENLIEVNSHVSEN 518
+ D + + V N S+DL + I K ++L+ V +S N
Sbjct: 1605 PDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAK--------ESLDTAAVVQVGISRN 1656
Query: 519 KNGSSNTGAKQAGPQDTVVYTRTYVENSKS 548
++ SS + + + TR++ ++ S
Sbjct: 1657 QSHSSPSVSPSRSHSPSGSQTRSHSSSASS 1686
Score = 35.0 bits (79), Expect = 0.21
Identities = 86/464 (18%), Positives = 170/464 (36%), Gaps = 35/464 (7%)
Query: 35 KRRTFLQDNSWIKKRPEEEKDENYGRVVLNRHNSHDALDRKVNERDVPKATISRYSSDDT 94
K T DN+ K +KDE H S A + + + + YS D
Sbjct: 1029 KEETPKTDNT--KSSSSSQKDEKITGTPRKAH-SKSAKEHQETKPVKEEKVKKDYSKDVK 1085
Query: 95 LDRISDRNDAAKTYKANTLDNQLTNRSMSMFRSLEVTKLQPGGSLNANTSNTIASTSATT 154
++++ + + AK K N + L N+ R E + ++ + + T
Sbjct: 1086 SEKLTTKEEKAK--KPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVK 1143
Query: 155 PV-KKKREPGVHPP--IPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNIRSQ 211
P K+K EP P K +S+P + + NR+ K G + + E + + +
Sbjct: 1144 PSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGK-KIGSTENISNTKEPSEKLE 1202
Query: 212 DLDNIVK---VATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSL 268
+ VK V ++R G E + ++ + + G + ++ K + + K++
Sbjct: 1203 STSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTM 1262
Query: 269 ESLIYMSTRTDKDGKGIQSLGSPIKVNQRTD-----KNEKGRQNLESVAKVNARMNKTSR 323
E Y + T I + P + D ++ K Q + SV K + + S
Sbjct: 1263 EE--YNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVST 1320
Query: 324 RSEDLDNATEVNPKGHENTTGGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGTEKSTE 383
+ ++ E + E + + EVK S + +EK
Sbjct: 1321 KPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSAS-----------SEKGKT 1369
Query: 384 GGQSLDSLIKVTPERNRTNQGNQDLENLIKV-----IPSANKSSEQGLDEHINVSPKAVK 438
+ L K PE+ + + + NL ++ S ++SS++ + S +A
Sbjct: 1370 KDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASS 1429
Query: 439 NTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQS 482
N D + DK + +++++R + L + + RN S
Sbjct: 1430 NKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDS 1473
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
Length = 1792
Score = 44.3 bits (103), Expect = 4e-04
Identities = 77/422 (18%), Positives = 163/422 (38%), Gaps = 54/422 (12%)
Query: 157 KKKREPGVHPPIP------PKPSSPVSSPNQLRQDN-----RQIHPPKPGVYTETNRSAE 205
+++R P PPI PK + SS + + + R+ H + ET E
Sbjct: 1048 ERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKE 1107
Query: 206 RNIR---SQDLDN---IVKVATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANP--- 256
++ S+D+ + K + + ++K + LDN + K +G+D F ++
Sbjct: 1108 EKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKI 1167
Query: 257 -KVEERE-----KRAKSLESLIYMSTRTDKDGKGIQSLGSPIKVNQRTDKNEKGRQNLES 310
K+E E + K M +KD + + IK+N+ T K +N+ +
Sbjct: 1168 SKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISN 1227
Query: 311 VAKVNARMNKTSRRSEDLDNATEVNPKGHENTTGGQ-SLDNLIKVT-------PEVKRSN 362
+ + ++ TS + + +V K TG + S L+ T V++S
Sbjct: 1228 TKEPSEKLESTSSKVKQ----EKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSE 1283
Query: 363 QGSKDLNNFIKVYPG-TEKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANKS 421
+ + IK +T + + +I+V + + + E++ P ++
Sbjct: 1284 EKTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVG 1343
Query: 422 SEQGLDEHINVSPKAV-----KNTDGKQDLDKLIK-VNPEIFTNNQRNQDLANLIKVNPA 475
+ ++++ P + K ++ + + K K V+ EI + ++ N A
Sbjct: 1344 KPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSK-------NSA 1396
Query: 476 VIRNNQSQDLDN--LIKVKPSALRNTNRDQNLENLIEVNSHVSENKNGSSNTGAKQAGPQ 533
+++D D L K P +N+ + + NL +N + S+ A+ +
Sbjct: 1397 SSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKH 1456
Query: 534 DT 535
D+
Sbjct: 1457 DS 1458
Score = 37.7 bits (86), Expect = 0.033
Identities = 102/570 (17%), Positives = 196/570 (34%), Gaps = 59/570 (10%)
Query: 7 RKMSPTGNEMKSTTQ------GTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGR 60
RKM P +M T + K+ + ++ +N K P E+ + +
Sbjct: 1182 RKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSK 1241
Query: 61 VVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTL------- 113
V + + RKV + +T+ Y+S + R KT T+
Sbjct: 1242 V--KQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEY 1299
Query: 114 DNQLTNRSMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKK--------KREPGVH 165
+N T + + ++V + + + + ST + V K +P
Sbjct: 1300 NNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNI 1359
Query: 166 PPIPPKPSSPVSSPNQLRQD------NRQIHPPKPGVYTETNRSAERNIRSQDLDNIVKV 219
P K S P + +D ++ K +E ++ +R+ + +N K
Sbjct: 1360 VKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKR 1419
Query: 220 ATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLI-YMSTRT 278
S Q E+ NL ++N+ N S A + RA S + +T
Sbjct: 1420 KNSTQP----EKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKT 1475
Query: 279 DKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKG 338
D D + S + N+ T + + +N +S + + NK R DL + K
Sbjct: 1476 DYDTREYSSSKRRDEKNELTRRKDSPSRNKDSAS---GQKNKP-REERDLPKKGTGDSKK 1531
Query: 339 HENTTGGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGTEKSTEGGQSLDSLIKVTPER 398
++ + K T + KR N+ +K ++ P ++ +
Sbjct: 1532 SNSSPSRDRKPHDHKATYDTKRPNEETKSVDK----NPCKDREKH---------VLEARN 1578
Query: 399 NRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVKNTDGKQDLDKLIKVNPEIFT 458
N+ + GN+ L L K G + V PK + + D + + F
Sbjct: 1579 NKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFE 1638
Query: 459 NNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRNTNRDQNLENLIEVNSHVSEN 518
+ D + + V N S+DL + I K ++L+ V +S N
Sbjct: 1639 PDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAK--------ESLDTAAVVQVGISRN 1690
Query: 519 KNGSSNTGAKQAGPQDTVVYTRTYVENSKS 548
++ SS + + + TR++ ++ S
Sbjct: 1691 QSHSSPSVSPSRSHSPSGSQTRSHSSSASS 1720
Score = 35.0 bits (79), Expect = 0.21
Identities = 86/464 (18%), Positives = 170/464 (36%), Gaps = 35/464 (7%)
Query: 35 KRRTFLQDNSWIKKRPEEEKDENYGRVVLNRHNSHDALDRKVNERDVPKATISRYSSDDT 94
K T DN+ K +KDE H S A + + + + YS D
Sbjct: 1063 KEETPKTDNT--KSSSSSQKDEKITGTPRKAH-SKSAKEHQETKPVKEEKVKKDYSKDVK 1119
Query: 95 LDRISDRNDAAKTYKANTLDNQLTNRSMSMFRSLEVTKLQPGGSLNANTSNTIASTSATT 154
++++ + + AK K N + L N+ R E + ++ + + T
Sbjct: 1120 SEKLTTKEEKAK--KPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVK 1177
Query: 155 PV-KKKREPGVHPP--IPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNIRSQ 211
P K+K EP P K +S+P + + NR+ K G + + E + + +
Sbjct: 1178 PSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGK-KIGSTENISNTKEPSEKLE 1236
Query: 212 DLDNIVK---VATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSL 268
+ VK V ++R G E + ++ + + G + ++ K + + K++
Sbjct: 1237 STSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTM 1296
Query: 269 ESLIYMSTRTDKDGKGIQSLGSPIKVNQRTD-----KNEKGRQNLESVAKVNARMNKTSR 323
E Y + T I + P + D ++ K Q + SV K + + S
Sbjct: 1297 EE--YNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVST 1354
Query: 324 RSEDLDNATEVNPKGHENTTGGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGTEKSTE 383
+ ++ E + E + + EVK S + +EK
Sbjct: 1355 KPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSAS-----------SEKGKT 1403
Query: 384 GGQSLDSLIKVTPERNRTNQGNQDLENLIKV-----IPSANKSSEQGLDEHINVSPKAVK 438
+ L K PE+ + + + NL ++ S ++SS++ + S +A
Sbjct: 1404 KDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASS 1463
Query: 439 NTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQS 482
N D + DK + +++++R + L + + RN S
Sbjct: 1464 NKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDS 1507
>gi|34303932 transmembrane and coiled-coil domains 5A [Homo sapiens]
Length = 288
Score = 41.6 bits (96), Expect = 0.002
Identities = 55/208 (26%), Positives = 86/208 (41%), Gaps = 45/208 (21%)
Query: 234 NLIKMNKSLNRN-QGLDSLFRANPK----VEEREKRAKSLESLIYMSTRTDKDGKGIQSL 288
N+I +N L R+ Q +D AN K ++ERE + + LES I + +G+
Sbjct: 12 NIISLNMDLERDTQRIDE---ANQKLLLKIQEREDKIQRLESEIIQT-------RGLVED 61
Query: 289 GSPIKVNQRTDKNEKGRQNLESVAKVNARMNKT------------SRRSEDLDNATEVNP 336
K N+ T + E+ Q LE R NKT +R+S+ + N + +P
Sbjct: 62 EEWEKENRTTMERERALQELEEETARLERKNKTLVHSITELQQKLTRKSQKITNCEQSSP 121
Query: 337 KG--HENTTGGQSLD--------NLIKVTPEVKRSNQGSKDLNNFIKVYPGTEKSTEG-- 384
G E Q L+ L+KV E Q +D +IK Y T K E
Sbjct: 122 DGALEETKVKLQQLEASYACQEKELLKVMKEYAFVTQLCEDQALYIKKYQETLKKIEEEL 181
Query: 385 -----GQSLDSLIKVTP-ERNRTNQGNQ 406
+ + L+ + P E+ T+Q N+
Sbjct: 182 EALFLEREVSKLVSMNPVEKEHTSQNNE 209
>gi|239757861 PREDICTED: similar to armadillo repeat containing,
X-linked 4 [Homo sapiens]
Length = 2382
Score = 41.2 bits (95), Expect = 0.003
Identities = 91/450 (20%), Positives = 157/450 (34%), Gaps = 72/450 (16%)
Query: 145 NTIASTSATTPVKKKREPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSA 204
NT K K PG+ +P + V +P + D+R P ++ A
Sbjct: 615 NTRGKARGKAKAKCKTGPGMDMKTCTQPQAGVKTPAEALLDSRVDGRGNPNATSKAGTKA 674
Query: 205 ERNIRSQDLDNIVKVATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANP----KVEE 260
++ + Q L + + +GE L G + + NP KV
Sbjct: 675 DQRVCGQPL---------VVANPQGEALP-------------GAKNKVKGNPHTVLKVGA 712
Query: 261 REKRAKSLESLIYMSTRTDKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNK 320
E S + +S + G LG+ KV + K ++ ++
Sbjct: 713 GEGTTDSAQPEAVVSFQ------GEALLGTKNKVKGNPNVVLKAEVGEGAMGTAQLQIMA 766
Query: 321 TSRRSEDLDNATEVNPKGHENTTGGQSLDNLIKVTPEVKRSNQGS--KDLNNFIKVYPGT 378
+S+ LD+ +V + + G D V P++ ++QG N I+ P T
Sbjct: 767 SSKGEALLDSKNKVKGNSNAVSKAGAGTDTTGSVQPQIVANSQGEVLPGAKNKIRGNPTT 826
Query: 379 -EKSTEGGQSLDSLIKVTPERNRTNQGN--QDLENLIKVIPSANKSSEQGLDEHINVSPK 435
S G + DS P+ +QG +N +K +A +E G+ +V P+
Sbjct: 827 VPNSGVGPYTTDS---ARPQAVANSQGEVLPGAKNKVKANLNAVSKAEAGMGATGSVQPQ 883
Query: 436 AVKN--------------------TDGKQDLDKLIKVNPEIFTNNQRN--QDLANLIKVN 473
AV N + +D P+ N+Q N +K N
Sbjct: 884 AVANSHCETLPGAKNKVRGNWNAVSKAGAGMDTRGSAQPQAVANSQGEVLPGAKNKVKGN 943
Query: 474 PAVIRNNQSQDLDNLIKVKPSALRNTNRDQNLENLIEVNSHVSENKNGSSNTGAKQ---- 529
P V+ +++ D + +P L ++ R E L + V N N S GA++
Sbjct: 944 PNVVSKAGARE-DTVGSTQPQVLASSQR----ETLPGARNKVKGNSNVVSKAGAREDTMG 998
Query: 530 -AGPQDTVVYTRTYVENSKSPKDGYQENIS 558
A PQ R + +++ G IS
Sbjct: 999 SAQPQVVANSQRETLPGARNKVKGNSNAIS 1028
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 39.3 bits (90), Expect = 0.011
Identities = 63/325 (19%), Positives = 123/325 (37%), Gaps = 38/325 (11%)
Query: 31 HEVNKRRTFLQDNSWIKKRPEEEKDENYGRVVLNRHNS------HDALDRKVNERDVPKA 84
++V KR + +K +E+D + R R S H+ + K + D
Sbjct: 450 NKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGK 509
Query: 85 TISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNRSMSMFRSLEVTKLQPGGSLNANTS 144
R S + ++ +++ K+ D + +RS R ++TK + S N+ T
Sbjct: 510 DQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRS----RECDITKGKH--SYNSRTR 563
Query: 145 NTIASTSATTPVKKKREPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSA 204
S + V+ + ++ R +++ H + Y RS
Sbjct: 564 ERSRSRDRSRRVRSRTH------------------DRDRSRSKEYHRYREQEYRRRGRSR 605
Query: 205 ERNIRSQDLDNIVKVATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKR 264
R R+ + K +R + E + NK RNQ S R E+
Sbjct: 606 SRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMY 665
Query: 265 AKSLESLIYMSTRTDKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESV--AKVNARMNKTS 322
+KS + + S+ ++ K + K+ Q + NE L++ K+ + + K +
Sbjct: 666 SKSRD---HNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKEN 722
Query: 323 RRS--EDLDNATEVNPK-GHENTTG 344
++S ++ D+ E N K HE++ G
Sbjct: 723 QKSKGQENDHVHEKNKKFDHESSPG 747
>gi|67551265 transcription factor ELYS [Homo sapiens]
Length = 2266
Score = 39.3 bits (90), Expect = 0.011
Identities = 76/387 (19%), Positives = 151/387 (39%), Gaps = 34/387 (8%)
Query: 82 PKATISRYSSDDTLDR----ISDRNDAAKTYKANTLDNQL--TNRSMSMFRSLEVTKLQP 135
P T+ + DT+D+ ++D D A+ A +D +L + ++ E +++P
Sbjct: 1547 PSGTLKLQYNFDTIDQQFCDLADNKDTAECDIAE-VDGELFVAQSNFTLILEGEEGEVEP 1605
Query: 136 GGSLNANTSNTIASTSATTPVKKKREPGVHPPIPPKPSSPVSSPNQLRQDNRQIHP-PKP 194
G +++ A+T+ + E H I PS+ S + D P P
Sbjct: 1606 GDFASSDVLPKAANTATEEKLVCSGENDNHGQIANLPSAVTSDQKSQKVDTLPYVPEPIK 1665
Query: 195 GVYTETNRSAERNIRSQDLDNIVKVATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRA 254
E ++ RS+++ TS E L+ N + + + S F+
Sbjct: 1666 VAIAENLLDVIKDTRSKEI-------TSDTMEQSIHETIPLVSQN-IMCPTKLVKSAFKT 1717
Query: 255 NPKVEEREKRAKSLESLIYMSTRTDKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKV 314
+ ++ ++ TRT G+ IQ++ + + + +SV K
Sbjct: 1718 AQETSTMTMNVSQVDDVVSSKTRTR--GQRIQNVNVKSAQQEASADVATPKMPGQSVRKK 1775
Query: 315 NARMNKTSRRSEDLDN------------ATEVNPK-GHENTTGGQS-LDNLIKVTPEVK- 359
+ + S SE++ + V P+ G Q L+N V E++
Sbjct: 1776 TRKAKEISEASENIYSDVRGLSQNQQIPQNSVTPRRGRRKKEVNQDILENTSSVEQELQI 1835
Query: 360 RSNQGSKDLNNFIKVYPGTEKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSAN 419
+ + SK L + + P E++T+ + S+ K TP R + + NQ+ +I + +
Sbjct: 1836 TTGRESKRLKSSQLLEPAVEETTKKEVKVSSVTKRTPRRIKRSVENQESVEIINDLKVST 1895
Query: 420 KSSEQGLDEHI-NVSPKAVKNTDGKQD 445
+S + + + + A +NT KQD
Sbjct: 1896 VTSPSRMIRKLRSTNLDASENTGNKQD 1922
>gi|38373673 synaptonemal complex protein 2 [Homo sapiens]
Length = 1530
Score = 39.3 bits (90), Expect = 0.011
Identities = 58/312 (18%), Positives = 123/312 (39%), Gaps = 25/312 (8%)
Query: 293 KVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKGHENTT---GGQSLD 349
K+ T E R+ SVAK + + + S+ L ++++P G E + +S
Sbjct: 386 KIFGATKHRESIRKQGISVAKTSLHILFDASGSQILVPESQISPVGEELVSLKEKSKSPK 445
Query: 350 NLIKVTPEVKRSNQGSKDLNNFIKVYPGTEKSTEGGQSLDSLIKVT-------------P 396
K + +K S++G+++ + K P K +E + + T P
Sbjct: 446 EFAKPSKYIKNSDKGNRNNSQLEKTTPSKRKMSEASMIVSGADRYTMRSPVLFSNTSIPP 505
Query: 397 ERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVKNTDGKQDLDKLIKVNPEI 456
R R Q + K PS +++SE +D ++ ++ + + ++DK IK +
Sbjct: 506 RRRRIKPPLQMTSSAEK--PSVSQTSENRVDNAASLKSRSSEGRHRRDNIDKHIKTAKCV 563
Query: 457 FTNNQRNQDL--ANLIKVNPAVIRNNQSQDLDNLIKVKPSALRNT--NRDQNLENLIEVN 512
+N + N ++ + + ++ D+ I P L N N+ +
Sbjct: 564 ENTENKNVEFPNQNFSELQDVIPDSQAAEKRDHTI--LPGVLDNICGNKIHSKWACWTPV 621
Query: 513 SHVSENKNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENISGKYIQTVYSTSDRS 572
+++ N ++T + QD V+ + + S S + +GK ++ +D
Sbjct: 622 TNIELCNNQRASTSSGDTLNQDIVINKKLTKQKSSSSISDHNSEGTGK-VKYKKEQTDHI 680
Query: 573 VIERDMCTYCRK 584
I++ C+K
Sbjct: 681 KIDKAEVEVCKK 692
>gi|14249338 BUD13 homolog isoform 1 [Homo sapiens]
Length = 619
Score = 38.9 bits (89), Expect = 0.015
Identities = 75/384 (19%), Positives = 140/384 (36%), Gaps = 59/384 (15%)
Query: 150 TSATTPVKKKRE--PGVHPPIPPKPSSPVSSPNQLRQDN-------------------RQ 188
+S T+P ++ R P PP P+ +S +SP ++R D+ R+
Sbjct: 184 SSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPRR 243
Query: 189 IHPPKPGVYTETNRSAE----RNIRSQDLDNIVKVATSLQRSDKGEELDNLIKMNKSLNR 244
+H P T S++ R R D V SL R+ G+ + +
Sbjct: 244 VHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWK 303
Query: 245 NQGLDSL-FRANPKVE-------EREKRAKS-------LESLIYMSTRTDKDGKGIQSLG 289
G L F N K E R+K+AKS L+S TD D +
Sbjct: 304 ESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQ 363
Query: 290 SPIKVNQRTD----KNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKG------H 339
SP + +D +N ++ +S R +T DL P G +
Sbjct: 364 SPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMY 423
Query: 340 ENTTGGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGTEKSTEGGQSLDSLIKVTPERN 399
G L ++ + E+K +Q + + Y T + G+ + ++ +R
Sbjct: 424 SGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQ-YAETVFRDKSGRKRNLKLERLEQRR 482
Query: 400 RTNQGNQDLENLIKVIP--SANKSSEQGLDEHINVSPKAVKNTDGKQDLDKLIKVNPEIF 457
+ + ++ E + + ++ +Q +++ + K + +DLD++++
Sbjct: 483 KAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARYIDDEDLDRMLR------ 536
Query: 458 TNNQRNQDLANLIKVNPAVIRNNQ 481
+ +AN IK N A N+
Sbjct: 537 EQEREGDPMANFIKKNKAKENKNK 560
>gi|115334679 retinoblastoma-binding protein 1 isoform III [Homo
sapiens]
Length = 1188
Score = 38.5 bits (88), Expect = 0.019
Identities = 73/422 (17%), Positives = 160/422 (37%), Gaps = 45/422 (10%)
Query: 183 RQDNRQIHPPKPGVYTET-----NRSAERNIRSQDLDNIVKVATSLQRSDKGEELDNLIK 237
RQ +++ PP + +++A +S + + +L+++ EEL +
Sbjct: 661 RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEKNLINEELSLKDE 720
Query: 238 MNKSLNRNQGLDSLFRANPKVEE---REKRAKSLESLIYMSTRTDKDGKGIQSLGSPIK- 293
+ K+ N N D L NPK+ +E ++ L + ++ + +Q G+ ++
Sbjct: 721 LEKNENLND--DKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGNKMEK 778
Query: 294 ---VNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKGHENTTGGQSLDN 350
V + +K+ KG+ ++ + K S ++ + +E + + H N
Sbjct: 779 TEEVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQN-EAGSEPHIEAHSLELSSLDNKN 837
Query: 351 LIKVTPEVKRSNQGSKDLNNFIKVYPGTEKSTEGGQSLDSLIKVTPERNRTNQGNQDLEN 410
T + K L I EK ++ V+ ER G++ ++N
Sbjct: 838 FSSATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNTVSQERTSDCIGSEGMKN 897
Query: 411 LI-------------KVIPSANKSSEQGLDEHINVSPKAVKNTDGKQDLDKLIKVNPEIF 457
L +I +N+ +Q E + + N K+D D + + PE
Sbjct: 898 LNFEQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPLIGPETL 957
Query: 458 TNNQRNQDLANLIKVNPAVIRN--NQSQDLDNLIKVKPSALRNTNRDQNLENLIEVNSHV 515
++ DL +L + + I + +S + ++L+ + P+ L +++ N V
Sbjct: 958 VCHE--VDLDDLDEKDKTSIEDVAVESSESNSLVSIPPA----------LPPVVQHNFSV 1005
Query: 516 SENKNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENISGKYIQTVYSTSDRSVIE 575
+ S + D + + E S ++G E S +T ++ S+I
Sbjct: 1006 ASPLTLSQDESRSVKSESDITIEVDSIAEES---QEGLCERESANGFETNVASGTCSIIV 1062
Query: 576 RD 577
++
Sbjct: 1063 QE 1064
>gi|115334673 retinoblastoma-binding protein 1 isoform II [Homo
sapiens]
Length = 1203
Score = 38.5 bits (88), Expect = 0.019
Identities = 73/422 (17%), Positives = 160/422 (37%), Gaps = 45/422 (10%)
Query: 183 RQDNRQIHPPKPGVYTET-----NRSAERNIRSQDLDNIVKVATSLQRSDKGEELDNLIK 237
RQ +++ PP + +++A +S + + +L+++ EEL +
Sbjct: 661 RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEKNLINEELSLKDE 720
Query: 238 MNKSLNRNQGLDSLFRANPKVEE---REKRAKSLESLIYMSTRTDKDGKGIQSLGSPIK- 293
+ K+ N N D L NPK+ +E ++ L + ++ + +Q G+ ++
Sbjct: 721 LEKNENLND--DKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGNKMEK 778
Query: 294 ---VNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKGHENTTGGQSLDN 350
V + +K+ KG+ ++ + K S ++ + +E + + H N
Sbjct: 779 TEEVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQN-EAGSEPHIEAHSLELSSLDNKN 837
Query: 351 LIKVTPEVKRSNQGSKDLNNFIKVYPGTEKSTEGGQSLDSLIKVTPERNRTNQGNQDLEN 410
T + K L I EK ++ V+ ER G++ ++N
Sbjct: 838 FSSATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNTVSQERTSDCIGSEGMKN 897
Query: 411 LI-------------KVIPSANKSSEQGLDEHINVSPKAVKNTDGKQDLDKLIKVNPEIF 457
L +I +N+ +Q E + + N K+D D + + PE
Sbjct: 898 LNFEQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPLIGPETL 957
Query: 458 TNNQRNQDLANLIKVNPAVIRN--NQSQDLDNLIKVKPSALRNTNRDQNLENLIEVNSHV 515
++ DL +L + + I + +S + ++L+ + P+ L +++ N V
Sbjct: 958 VCHE--VDLDDLDEKDKTSIEDVAVESSESNSLVSIPPA----------LPPVVQHNFSV 1005
Query: 516 SENKNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENISGKYIQTVYSTSDRSVIE 575
+ S + D + + E S ++G E S +T ++ S+I
Sbjct: 1006 ASPLTLSQDESRSVKSESDITIEVDSIAEES---QEGLCERESANGFETNVASGTCSIIV 1062
Query: 576 RD 577
++
Sbjct: 1063 QE 1064
>gi|115334677 retinoblastoma-binding protein 1 isoform I [Homo
sapiens]
Length = 1257
Score = 38.5 bits (88), Expect = 0.019
Identities = 73/422 (17%), Positives = 160/422 (37%), Gaps = 45/422 (10%)
Query: 183 RQDNRQIHPPKPGVYTET-----NRSAERNIRSQDLDNIVKVATSLQRSDKGEELDNLIK 237
RQ +++ PP + +++A +S + + +L+++ EEL +
Sbjct: 661 RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEKNLINEELSLKDE 720
Query: 238 MNKSLNRNQGLDSLFRANPKVEE---REKRAKSLESLIYMSTRTDKDGKGIQSLGSPIK- 293
+ K+ N N D L NPK+ +E ++ L + ++ + +Q G+ ++
Sbjct: 721 LEKNENLND--DKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGNKMEK 778
Query: 294 ---VNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKGHENTTGGQSLDN 350
V + +K+ KG+ ++ + K S ++ + +E + + H N
Sbjct: 779 TEEVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQN-EAGSEPHIEAHSLELSSLDNKN 837
Query: 351 LIKVTPEVKRSNQGSKDLNNFIKVYPGTEKSTEGGQSLDSLIKVTPERNRTNQGNQDLEN 410
T + K L I EK ++ V+ ER G++ ++N
Sbjct: 838 FSSATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNTVSQERTSDCIGSEGMKN 897
Query: 411 LI-------------KVIPSANKSSEQGLDEHINVSPKAVKNTDGKQDLDKLIKVNPEIF 457
L +I +N+ +Q E + + N K+D D + + PE
Sbjct: 898 LNFEQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPLIGPETL 957
Query: 458 TNNQRNQDLANLIKVNPAVIRN--NQSQDLDNLIKVKPSALRNTNRDQNLENLIEVNSHV 515
++ DL +L + + I + +S + ++L+ + P+ L +++ N V
Sbjct: 958 VCHE--VDLDDLDEKDKTSIEDVAVESSESNSLVSIPPA----------LPPVVQHNFSV 1005
Query: 516 SENKNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENISGKYIQTVYSTSDRSVIE 575
+ S + D + + E S ++G E S +T ++ S+I
Sbjct: 1006 ASPLTLSQDESRSVKSESDITIEVDSIAEES---QEGLCERESANGFETNVASGTCSIIV 1062
Query: 576 RD 577
++
Sbjct: 1063 QE 1064
>gi|228480221 four and a half LIM domains 1 isoform 4 [Homo sapiens]
Length = 194
Score = 38.1 bits (87), Expect = 0.025
Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Query: 579 CTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLEN 617
C CRKP+G ++K + + + H TCF+C C PL N
Sbjct: 40 CVECRKPIGADSKEVHYKNRFW-HDTCFRCAKCLHPLAN 77
>gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 38.1 bits (87), Expect = 0.025
Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Query: 579 CTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLEN 617
C CRKP+G ++K + + + H TCF+C C PL N
Sbjct: 40 CVECRKPIGADSKEVHYKNRFW-HDTCFRCAKCLHPLAN 77
>gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens]
Length = 323
Score = 38.1 bits (87), Expect = 0.025
Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Query: 579 CTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLEN 617
C CRKP+G ++K + + + H TCF+C C PL N
Sbjct: 40 CVECRKPIGADSKEVHYKNRFW-HDTCFRCAKCLHPLAN 77
>gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 38.1 bits (87), Expect = 0.025
Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Query: 579 CTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLEN 617
C CRKP+G ++K + + + H TCF+C C PL N
Sbjct: 40 CVECRKPIGADSKEVHYKNRFW-HDTCFRCAKCLHPLAN 77
>gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]
Length = 309
Score = 38.1 bits (87), Expect = 0.025
Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Query: 579 CTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLEN 617
C CRKP+G ++K + + + H TCF+C C PL N
Sbjct: 69 CVECRKPIGADSKEVHYKNRFW-HDTCFRCAKCLHPLAN 106
>gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]
Length = 296
Score = 38.1 bits (87), Expect = 0.025
Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Query: 579 CTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLEN 617
C CRKP+G ++K + + + H TCF+C C PL N
Sbjct: 56 CVECRKPIGADSKEVHYKNRFW-HDTCFRCAKCLHPLAN 93
>gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 38.1 bits (87), Expect = 0.025
Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Query: 579 CTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLEN 617
C CRKP+G ++K + + + H TCF+C C PL N
Sbjct: 40 CVECRKPIGADSKEVHYKNRFW-HDTCFRCAKCLHPLAN 77
>gi|55770895 ERBB2 interacting protein isoform 7 [Homo sapiens]
Length = 1302
Score = 37.7 bits (86), Expect = 0.033
Identities = 74/359 (20%), Positives = 143/359 (39%), Gaps = 57/359 (15%)
Query: 212 DLDNIVKVATSLQRSDKGEELDNLIKMN-------KSLNRNQGL---DSLFRANPKVEER 261
+L N+VK ++ K EE + + + +N++ G+ +S KV+ER
Sbjct: 490 ELKNMVKTVQTIVHRLKDEETNEDSGRDLKPHEDQQDINKDVGVKTSESTTTVKSKVDER 549
Query: 262 EKRAKSLESLIYMSTRTDKDGKGIQSLGS-PIKVNQRTDKNEKGRQNLESVAKVNARMNK 320
EK +I S + + + S GS P+ N + +N K N + V + + ++
Sbjct: 550 EKY------MIGNSVQKISEPEAEISPGSLPVTANMKASENLKHIVNHDDVFEESEELSS 603
Query: 321 TSRRS---------EDLDNATEVNPKGHENTTGGQSLDNLIKVTPEVKR-SNQGSKDLNN 370
E N +V + + D+L + EV SNQ + + ++
Sbjct: 604 DEEMKMAEMRPPLIETSINQPKVVALSNNKKDDTKETDSL---SDEVTHNSNQNNSNCSS 660
Query: 371 FIKVYPGTEKSTEGGQ--SLDSLIKVT--PERNRTNQGNQDLENLIKVIPSANKSSEQ-- 424
++ +T+ Q SL S +K T ++ Q +++ +L++ N S+E+
Sbjct: 661 PSRMSDSVSLNTDSSQDTSLCSPVKQTHIDINSKIRQEDENFNSLLQNGDILNSSTEEKF 720
Query: 425 ---------------GLDEHINVSPKAVKNTDGKQDLDKLIKVNP---EIFTNNQRNQDL 466
++E + + K+V +T D KL +N ++ TN+ ++
Sbjct: 721 KAHDKKDFNLPEYDLNVEERLVLIEKSVDSTATADDTHKLDHINMNLNKLITNDTFQPEI 780
Query: 467 ANLIKVNPAVIRNNQSQDLDNLIKVKPSALRNTNRDQNLENLIEVNSHVSENKNGSSNT 525
K V+ + L K + L N N+ NLE++ +VN H E + T
Sbjct: 781 MERSKTQDIVLGTSF---LSINSKEETEHLENGNKYPNLESVNKVNGHSEETSQSPNRT 836
>gi|8923909 ERBB2 interacting protein isoform 2 [Homo sapiens]
Length = 1371
Score = 37.7 bits (86), Expect = 0.033
Identities = 74/359 (20%), Positives = 143/359 (39%), Gaps = 57/359 (15%)
Query: 212 DLDNIVKVATSLQRSDKGEELDNLIKMN-------KSLNRNQGL---DSLFRANPKVEER 261
+L N+VK ++ K EE + + + +N++ G+ +S KV+ER
Sbjct: 490 ELKNMVKTVQTIVHRLKDEETNEDSGRDLKPHEDQQDINKDVGVKTSESTTTVKSKVDER 549
Query: 262 EKRAKSLESLIYMSTRTDKDGKGIQSLGS-PIKVNQRTDKNEKGRQNLESVAKVNARMNK 320
EK +I S + + + S GS P+ N + +N K N + V + + ++
Sbjct: 550 EKY------MIGNSVQKISEPEAEISPGSLPVTANMKASENLKHIVNHDDVFEESEELSS 603
Query: 321 TSRRS---------EDLDNATEVNPKGHENTTGGQSLDNLIKVTPEVKR-SNQGSKDLNN 370
E N +V + + D+L + EV SNQ + + ++
Sbjct: 604 DEEMKMAEMRPPLIETSINQPKVVALSNNKKDDTKETDSL---SDEVTHNSNQNNSNCSS 660
Query: 371 FIKVYPGTEKSTEGGQ--SLDSLIKVT--PERNRTNQGNQDLENLIKVIPSANKSSEQ-- 424
++ +T+ Q SL S +K T ++ Q +++ +L++ N S+E+
Sbjct: 661 PSRMSDSVSLNTDSSQDTSLCSPVKQTHIDINSKIRQEDENFNSLLQNGDILNSSTEEKF 720
Query: 425 ---------------GLDEHINVSPKAVKNTDGKQDLDKLIKVNP---EIFTNNQRNQDL 466
++E + + K+V +T D KL +N ++ TN+ ++
Sbjct: 721 KAHDKKDFNLPEYDLNVEERLVLIEKSVDSTATADDTHKLDHINMNLNKLITNDTFQPEI 780
Query: 467 ANLIKVNPAVIRNNQSQDLDNLIKVKPSALRNTNRDQNLENLIEVNSHVSENKNGSSNT 525
K V+ + L K + L N N+ NLE++ +VN H E + T
Sbjct: 781 MERSKTQDIVLGTSF---LSINSKEETEHLENGNKYPNLESVNKVNGHSEETSQSPNRT 836
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.126 0.351
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,917,635
Number of Sequences: 37866
Number of extensions: 1199912
Number of successful extensions: 5908
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 226
Number of HSP's that attempted gapping in prelim test: 5357
Number of HSP's gapped (non-prelim): 527
length of query: 646
length of database: 18,247,518
effective HSP length: 109
effective length of query: 537
effective length of database: 14,120,124
effective search space: 7582506588
effective search space used: 7582506588
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.