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Search of human proteins with 238908497
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|238908497 sciellin isoform 2 [Homo sapiens]
(668 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|238908497 sciellin isoform 2 [Homo sapiens] 1346 0.0
gi|238908499 sciellin isoform 1 [Homo sapiens] 1332 0.0
gi|238908501 sciellin isoform 3 [Homo sapiens] 1214 0.0
gi|148298722 zinc finger protein 185 [Homo sapiens] 70 5e-12
gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens] 58 3e-08
gi|163310741 LIM and calponin homology domains 1 isoform a [Homo... 56 1e-07
gi|163310749 LIM and calponin homology domains 1 isoform e [Homo... 55 3e-07
gi|163310747 LIM and calponin homology domains 1 isoform d [Homo... 55 3e-07
gi|163310745 LIM and calponin homology domains 1 isoform c [Homo... 55 3e-07
gi|163310743 LIM and calponin homology domains 1 isoform b [Homo... 55 3e-07
gi|115334679 retinoblastoma-binding protein 1 isoform III [Homo ... 43 0.001
gi|115334673 retinoblastoma-binding protein 1 isoform II [Homo s... 43 0.001
gi|115334677 retinoblastoma-binding protein 1 isoform I [Homo sa... 43 0.001
gi|222352143 TBC1 domain family, member 2 [Homo sapiens] 41 0.003
gi|239757861 PREDICTED: similar to armadillo repeat containing, ... 41 0.004
gi|55770895 ERBB2 interacting protein isoform 7 [Homo sapiens] 41 0.004
gi|8923909 ERBB2 interacting protein isoform 2 [Homo sapiens] 41 0.004
gi|71061468 centromere protein E [Homo sapiens] 39 0.012
gi|47578107 delangin isoform B [Homo sapiens] 39 0.012
gi|47578105 delangin isoform A [Homo sapiens] 39 0.012
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 39 0.015
gi|228480221 four and a half LIM domains 1 isoform 4 [Homo sapiens] 38 0.026
gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens] 38 0.026
gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens] 38 0.026
gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens] 38 0.026
gi|11415052 retinoid X receptor, beta [Homo sapiens] 38 0.026
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 38 0.026
gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens] 38 0.026
gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens] 38 0.026
gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens] 38 0.026
>gi|238908497 sciellin isoform 2 [Homo sapiens]
Length = 668
Score = 1346 bits (3483), Expect = 0.0
Identities = 668/668 (100%), Positives = 668/668 (100%)
Query: 1 MSNVTLRKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGR 60
MSNVTLRKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGR
Sbjct: 1 MSNVTLRKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGR 60
Query: 61 VVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNR 120
VVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNR
Sbjct: 61 VVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNR 120
Query: 121 SMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKKRQSWFPPPPPGYNASSSTGTR 180
SMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKKRQSWFPPPPPGYNASSSTGTR
Sbjct: 121 SMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKKRQSWFPPPPPGYNASSSTGTR 180
Query: 181 RREPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNISEELDNLIKM 240
RREPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNISEELDNLIKM
Sbjct: 181 RREPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNISEELDNLIKM 240
Query: 241 NKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRTDKDGKGIQSLGSPIKVNQRT 300
NKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRTDKDGKGIQSLGSPIKVNQRT
Sbjct: 241 NKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRTDKDGKGIQSLGSPIKVNQRT 300
Query: 301 DKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKGHENTTGKKDLDGLIKVDPET 360
DKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKGHENTTGKKDLDGLIKVDPET
Sbjct: 301 DKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKGHENTTGKKDLDGLIKVDPET 360
Query: 361 NKNITRGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGTEKSTEGGQSLDSLIKVTPER 420
NKNITRGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGTEKSTEGGQSLDSLIKVTPER
Sbjct: 361 NKNITRGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGTEKSTEGGQSLDSLIKVTPER 420
Query: 421 NRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVKNTDGKQDLDKLIKVNPEIFT 480
NRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVKNTDGKQDLDKLIKVNPEIFT
Sbjct: 421 NRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVKNTDGKQDLDKLIKVNPEIFT 480
Query: 481 NNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRNTNRDQNLENLIEVNSHVSEN 540
NNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRNTNRDQNLENLIEVNSHVSEN
Sbjct: 481 NNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRNTNRDQNLENLIEVNSHVSEN 540
Query: 541 KNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENISGKYIQTVYSTSDRSVIERDM 600
KNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENISGKYIQTVYSTSDRSVIERDM
Sbjct: 541 KNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENISGKYIQTVYSTSDRSVIERDM 600
Query: 601 CTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYS 660
CTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYS
Sbjct: 601 CTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYS 660
Query: 661 KIMAKWIP 668
KIMAKWIP
Sbjct: 661 KIMAKWIP 668
>gi|238908499 sciellin isoform 1 [Homo sapiens]
Length = 688
Score = 1332 bits (3448), Expect = 0.0
Identities = 667/688 (96%), Positives = 667/688 (96%), Gaps = 20/688 (2%)
Query: 1 MSNVTLRKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGR 60
MSNVTLRKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGR
Sbjct: 1 MSNVTLRKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGR 60
Query: 61 VVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNR 120
VVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNR
Sbjct: 61 VVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNR 120
Query: 121 SMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKKRQSWFPPPPPGYNASSSTGTR 180
SMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKKRQSWFPPPPPGYNASSSTGTR
Sbjct: 121 SMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKKRQSWFPPPPPGYNASSSTGTR 180
Query: 181 RREPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNI---------- 230
RREPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNI
Sbjct: 181 RREPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNIRSQDLDNIVK 240
Query: 231 ----------SEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRT 280
EELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRT
Sbjct: 241 VATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRT 300
Query: 281 DKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKG 340
DKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKG
Sbjct: 301 DKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKG 360
Query: 341 HENTTGKKDLDGLIKVDPETNKNITRGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGT 400
HENTTGKKDLDGLIKVDPETNKNITRGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGT
Sbjct: 361 HENTTGKKDLDGLIKVDPETNKNITRGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGT 420
Query: 401 EKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVK 460
EKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVK
Sbjct: 421 EKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVK 480
Query: 461 NTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRN 520
NTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRN
Sbjct: 481 NTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRN 540
Query: 521 TNRDQNLENLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENIS 580
TNRDQNLENLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENIS
Sbjct: 541 TNRDQNLENLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENIS 600
Query: 581 GKYIQTVYSTSDRSVIERDMCTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENL 640
GKYIQTVYSTSDRSVIERDMCTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENL
Sbjct: 601 GKYIQTVYSTSDRSVIERDMCTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENL 660
Query: 641 QAGDSIWIYRQTIHCEPCYSKIMAKWIP 668
QAGDSIWIYRQTIHCEPCYSKIMAKWIP
Sbjct: 661 QAGDSIWIYRQTIHCEPCYSKIMAKWIP 688
>gi|238908501 sciellin isoform 3 [Homo sapiens]
Length = 646
Score = 1214 bits (3140), Expect = 0.0
Identities = 623/688 (90%), Positives = 623/688 (90%), Gaps = 62/688 (9%)
Query: 1 MSNVTLRKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGR 60
MSNVTLRKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGR
Sbjct: 1 MSNVTLRKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGR 60
Query: 61 VVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNR 120
VVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNR
Sbjct: 61 VVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNR 120
Query: 121 SMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKKRQSWFPPPPPGYNASSSTGTR 180
SMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKKR
Sbjct: 121 SMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKKR-------------------- 160
Query: 181 RREPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNI---------- 230
EPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNI
Sbjct: 161 --EPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNIRSQDLDNIVK 218
Query: 231 ----------SEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRT 280
EELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRT
Sbjct: 219 VATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRT 278
Query: 281 DKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKG 340
DKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKG
Sbjct: 279 DKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKG 338
Query: 341 HENTTGKKDLDGLIKVDPETNKNITRGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGT 400
HE N T GQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGT
Sbjct: 339 HE--------------------NTTGGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGT 378
Query: 401 EKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVK 460
EKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVK
Sbjct: 379 EKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVK 438
Query: 461 NTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRN 520
NTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRN
Sbjct: 439 NTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRN 498
Query: 521 TNRDQNLENLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENIS 580
TNRDQNLENLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENIS
Sbjct: 499 TNRDQNLENLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENIS 558
Query: 581 GKYIQTVYSTSDRSVIERDMCTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENL 640
GKYIQTVYSTSDRSVIERDMCTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENL
Sbjct: 559 GKYIQTVYSTSDRSVIERDMCTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENL 618
Query: 641 QAGDSIWIYRQTIHCEPCYSKIMAKWIP 668
QAGDSIWIYRQTIHCEPCYSKIMAKWIP
Sbjct: 619 QAGDSIWIYRQTIHCEPCYSKIMAKWIP 646
>gi|148298722 zinc finger protein 185 [Homo sapiens]
Length = 689
Score = 70.5 bits (171), Expect = 5e-12
Identities = 30/63 (47%), Positives = 41/63 (65%), Gaps = 2/63 (3%)
Query: 600 MCTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCY 659
+CTYC + + K+ L+ L ICCH CFKC IC +P+ +L D I+I+R TIHC CY
Sbjct: 628 ICTYCNREIRDCPKITLEHLGICCHEYCFKCGICSKPMGDLL--DQIFIHRDTIHCGKCY 685
Query: 660 SKI 662
K+
Sbjct: 686 EKL 688
>gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens]
Length = 1349
Score = 57.8 bits (138), Expect = 3e-08
Identities = 36/119 (30%), Positives = 55/119 (46%), Gaps = 6/119 (5%)
Query: 541 KNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENISGKYIQTVYSTSDRSVIERDM 600
+N SS+ AG T + T V ++SP + S Q+ +RSV + +
Sbjct: 1226 RNPSSSVPPPSAGSVKT---STTGVATTQSPTP---RSHSPSASQSGSQLRNRSVSGKRI 1279
Query: 601 CTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCY 659
C+YC LG MI++ L +C H CFKC C+ L +G + I ++C CY
Sbjct: 1280 CSYCNNILGKGAAMIIESLGLCYHLHCFKCVACECDLGGSSSGAEVRIRNHQLYCNDCY 1338
Score = 29.6 bits (65), Expect = 9.4
Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 9/68 (13%)
Query: 7 RKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGRV-VLNR 65
++ P+G E++ +QQ E+ KR DNSWI++R E ++ R
Sbjct: 1122 KEQVPSGAELE--------RQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRR 1173
Query: 66 HNSHDALD 73
S D LD
Sbjct: 1174 GESLDNLD 1181
>gi|163310741 LIM and calponin homology domains 1 isoform a [Homo
sapiens]
Length = 1083
Score = 55.8 bits (133), Expect = 1e-07
Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 1/94 (1%)
Query: 569 KSPKDGYQENISGKYIQTVYSTS-DRSVIERDMCTYCRKPLGVETKMILDELQICCHSTC 627
KSP++ +Q T S +RS+ + +C+ C PLG MI++ L + H C
Sbjct: 980 KSPREHFQAGPFSPCSPTPPGQSPNRSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQC 1039
Query: 628 FKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSK 661
F+C ICK L + +G + I ++C CY +
Sbjct: 1040 FRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMR 1073
>gi|163310749 LIM and calponin homology domains 1 isoform e [Homo
sapiens]
Length = 890
Score = 54.7 bits (130), Expect = 3e-07
Identities = 43/177 (24%), Positives = 75/177 (42%), Gaps = 24/177 (13%)
Query: 503 QSQDLDNLIKVKPSALRNTNRDQNLENLIE---------VNSHVSENKNGSSNTGAKQAG 553
Q D D L+K R ++R + +L E V+ V E+ + GA G
Sbjct: 710 QGDDSDLLLKT-----RESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCG 764
Query: 554 PQDTVVYTRTYVENSKSPKDGYQENISGKYI-------QTVYSTSDR--SVIERDMCTYC 604
+ + + + +P E++ K + + S S+R S+ + +C+ C
Sbjct: 765 TNPQLAQDPSQNQQTSNPTHS-SEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSC 823
Query: 605 RKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSK 661
PLG MI++ L + H CF+C ICK L + +G + I ++C CY +
Sbjct: 824 GLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMR 880
>gi|163310747 LIM and calponin homology domains 1 isoform d [Homo
sapiens]
Length = 902
Score = 54.7 bits (130), Expect = 3e-07
Identities = 43/177 (24%), Positives = 75/177 (42%), Gaps = 24/177 (13%)
Query: 503 QSQDLDNLIKVKPSALRNTNRDQNLENLIE---------VNSHVSENKNGSSNTGAKQAG 553
Q D D L+K R ++R + +L E V+ V E+ + GA G
Sbjct: 722 QGDDSDLLLKT-----RESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCG 776
Query: 554 PQDTVVYTRTYVENSKSPKDGYQENISGKYI-------QTVYSTSDR--SVIERDMCTYC 604
+ + + + +P E++ K + + S S+R S+ + +C+ C
Sbjct: 777 TNPQLAQDPSQNQQTSNPTHS-SEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSC 835
Query: 605 RKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSK 661
PLG MI++ L + H CF+C ICK L + +G + I ++C CY +
Sbjct: 836 GLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMR 892
>gi|163310745 LIM and calponin homology domains 1 isoform c [Homo
sapiens]
Length = 1056
Score = 54.7 bits (130), Expect = 3e-07
Identities = 43/177 (24%), Positives = 75/177 (42%), Gaps = 24/177 (13%)
Query: 503 QSQDLDNLIKVKPSALRNTNRDQNLENLIE---------VNSHVSENKNGSSNTGAKQAG 553
Q D D L+K R ++R + +L E V+ V E+ + GA G
Sbjct: 876 QGDDSDLLLKT-----RESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCG 930
Query: 554 PQDTVVYTRTYVENSKSPKDGYQENISGKYI-------QTVYSTSDR--SVIERDMCTYC 604
+ + + + +P E++ K + + S S+R S+ + +C+ C
Sbjct: 931 TNPQLAQDPSQNQQTSNPTHS-SEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSC 989
Query: 605 RKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSK 661
PLG MI++ L + H CF+C ICK L + +G + I ++C CY +
Sbjct: 990 GLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMR 1046
>gi|163310743 LIM and calponin homology domains 1 isoform b [Homo
sapiens]
Length = 1057
Score = 54.7 bits (130), Expect = 3e-07
Identities = 43/177 (24%), Positives = 75/177 (42%), Gaps = 24/177 (13%)
Query: 503 QSQDLDNLIKVKPSALRNTNRDQNLENLIE---------VNSHVSENKNGSSNTGAKQAG 553
Q D D L+K R ++R + +L E V+ V E+ + GA G
Sbjct: 877 QGDDSDLLLKT-----RESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCG 931
Query: 554 PQDTVVYTRTYVENSKSPKDGYQENISGKYI-------QTVYSTSDR--SVIERDMCTYC 604
+ + + + +P E++ K + + S S+R S+ + +C+ C
Sbjct: 932 TNPQLAQDPSQNQQTSNPTHS-SEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSC 990
Query: 605 RKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSK 661
PLG MI++ L + H CF+C ICK L + +G + I ++C CY +
Sbjct: 991 GLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMR 1047
>gi|115334679 retinoblastoma-binding protein 1 isoform III [Homo
sapiens]
Length = 1188
Score = 42.7 bits (99), Expect = 0.001
Identities = 76/392 (19%), Positives = 160/392 (40%), Gaps = 39/392 (9%)
Query: 220 TETNRSAERN-ISEELDNLIKMNKSLNRNQGLDSLFRANPKVEE---REKRAKSLESLIY 275
+ET + E+N I+EEL ++ K+ N N D L NPK+ +E ++ L
Sbjct: 700 SETEDALEKNLINEELSLKDELEKNENLND--DKLDEENPKISAHILKENDRTQMQPLET 757
Query: 276 MSTRTDKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATE 335
+ ++ + +Q G+ + +K E+ ++ E K R +KT S ++ +
Sbjct: 758 LKLEVGENEQIVQIFGN------KMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEI---IK 808
Query: 336 VNPKGHENTTGKKDLDG-LIKVDPETNKNITRG--QSLDNLIKVTPEVKRSNQGSKDLNN 392
++ G + ++ +++ NKN + +D +K ++KR G
Sbjct: 809 ISSFGQNEAGSEPHIEAHSLELSSLDNKNFSSATEDEIDQCVK-EKKLKRKILGQSSPEK 867
Query: 393 FIKVYPGTEKSTEGGQSLDS-LIKVTPERNRTNQGNQDLEN--LIKVIPSANKSSEQGLD 449
I++ G E + Q S I +N + + + EN + +I +N+ +Q
Sbjct: 868 KIRIENGMEMTNTVSQERTSDCIGSEGMKNLNFEQHFERENEGMPSLIAESNQCIQQLTS 927
Query: 450 EHINVSPKAVKNTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRN--NQSQDL 507
E + + N K+D D + + PE ++ DL +L + + I + +S +
Sbjct: 928 ERFDSPAEETVNIPLKEDEDAMPLIGPETLVCHE--VDLDDLDEKDKTSIEDVAVESSES 985
Query: 508 DNLIKVKPSALRNTNRDQNLENLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTRTYVEN 567
++L+ + P+ L +++ N V+ S + D + + E
Sbjct: 986 NSLVSIPPA----------LPPVVQHNFSVASPLTLSQDESRSVKSESDITIEVDSIAEE 1035
Query: 568 SKSPKDGYQENISGKYIQTVYSTSDRSVIERD 599
S ++G E S +T ++ S+I ++
Sbjct: 1036 S---QEGLCERESANGFETNVASGTCSIIVQE 1064
>gi|115334673 retinoblastoma-binding protein 1 isoform II [Homo
sapiens]
Length = 1203
Score = 42.7 bits (99), Expect = 0.001
Identities = 76/392 (19%), Positives = 160/392 (40%), Gaps = 39/392 (9%)
Query: 220 TETNRSAERN-ISEELDNLIKMNKSLNRNQGLDSLFRANPKVEE---REKRAKSLESLIY 275
+ET + E+N I+EEL ++ K+ N N D L NPK+ +E ++ L
Sbjct: 700 SETEDALEKNLINEELSLKDELEKNENLND--DKLDEENPKISAHILKENDRTQMQPLET 757
Query: 276 MSTRTDKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATE 335
+ ++ + +Q G+ + +K E+ ++ E K R +KT S ++ +
Sbjct: 758 LKLEVGENEQIVQIFGN------KMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEI---IK 808
Query: 336 VNPKGHENTTGKKDLDG-LIKVDPETNKNITRG--QSLDNLIKVTPEVKRSNQGSKDLNN 392
++ G + ++ +++ NKN + +D +K ++KR G
Sbjct: 809 ISSFGQNEAGSEPHIEAHSLELSSLDNKNFSSATEDEIDQCVK-EKKLKRKILGQSSPEK 867
Query: 393 FIKVYPGTEKSTEGGQSLDS-LIKVTPERNRTNQGNQDLEN--LIKVIPSANKSSEQGLD 449
I++ G E + Q S I +N + + + EN + +I +N+ +Q
Sbjct: 868 KIRIENGMEMTNTVSQERTSDCIGSEGMKNLNFEQHFERENEGMPSLIAESNQCIQQLTS 927
Query: 450 EHINVSPKAVKNTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRN--NQSQDL 507
E + + N K+D D + + PE ++ DL +L + + I + +S +
Sbjct: 928 ERFDSPAEETVNIPLKEDEDAMPLIGPETLVCHE--VDLDDLDEKDKTSIEDVAVESSES 985
Query: 508 DNLIKVKPSALRNTNRDQNLENLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTRTYVEN 567
++L+ + P+ L +++ N V+ S + D + + E
Sbjct: 986 NSLVSIPPA----------LPPVVQHNFSVASPLTLSQDESRSVKSESDITIEVDSIAEE 1035
Query: 568 SKSPKDGYQENISGKYIQTVYSTSDRSVIERD 599
S ++G E S +T ++ S+I ++
Sbjct: 1036 S---QEGLCERESANGFETNVASGTCSIIVQE 1064
>gi|115334677 retinoblastoma-binding protein 1 isoform I [Homo
sapiens]
Length = 1257
Score = 42.7 bits (99), Expect = 0.001
Identities = 76/392 (19%), Positives = 160/392 (40%), Gaps = 39/392 (9%)
Query: 220 TETNRSAERN-ISEELDNLIKMNKSLNRNQGLDSLFRANPKVEE---REKRAKSLESLIY 275
+ET + E+N I+EEL ++ K+ N N D L NPK+ +E ++ L
Sbjct: 700 SETEDALEKNLINEELSLKDELEKNENLND--DKLDEENPKISAHILKENDRTQMQPLET 757
Query: 276 MSTRTDKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATE 335
+ ++ + +Q G+ + +K E+ ++ E K R +KT S ++ +
Sbjct: 758 LKLEVGENEQIVQIFGN------KMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEI---IK 808
Query: 336 VNPKGHENTTGKKDLDG-LIKVDPETNKNITRG--QSLDNLIKVTPEVKRSNQGSKDLNN 392
++ G + ++ +++ NKN + +D +K ++KR G
Sbjct: 809 ISSFGQNEAGSEPHIEAHSLELSSLDNKNFSSATEDEIDQCVK-EKKLKRKILGQSSPEK 867
Query: 393 FIKVYPGTEKSTEGGQSLDS-LIKVTPERNRTNQGNQDLEN--LIKVIPSANKSSEQGLD 449
I++ G E + Q S I +N + + + EN + +I +N+ +Q
Sbjct: 868 KIRIENGMEMTNTVSQERTSDCIGSEGMKNLNFEQHFERENEGMPSLIAESNQCIQQLTS 927
Query: 450 EHINVSPKAVKNTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRN--NQSQDL 507
E + + N K+D D + + PE ++ DL +L + + I + +S +
Sbjct: 928 ERFDSPAEETVNIPLKEDEDAMPLIGPETLVCHE--VDLDDLDEKDKTSIEDVAVESSES 985
Query: 508 DNLIKVKPSALRNTNRDQNLENLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTRTYVEN 567
++L+ + P+ L +++ N V+ S + D + + E
Sbjct: 986 NSLVSIPPA----------LPPVVQHNFSVASPLTLSQDESRSVKSESDITIEVDSIAEE 1035
Query: 568 SKSPKDGYQENISGKYIQTVYSTSDRSVIERD 599
S ++G E S +T ++ S+I ++
Sbjct: 1036 S---QEGLCERESANGFETNVASGTCSIIVQE 1064
>gi|222352143 TBC1 domain family, member 2 [Homo sapiens]
Length = 917
Score = 41.2 bits (95), Expect = 0.003
Identities = 33/145 (22%), Positives = 63/145 (43%), Gaps = 8/145 (5%)
Query: 174 SSSTGTRRREPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNISEE 233
+S T REP P PKPS +S + ++ N G+ NR+A+ ++
Sbjct: 254 ASDASTPGREPEDSPKPAPKPSLTISFAQKAKRQNNTFPFFSEGI--TRNRTAQEKVAAL 311
Query: 234 LDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRTDKDGKGI--QSLG 291
++ + K L + L + + ++EKRA S Y++ DKD + +
Sbjct: 312 EQQVLMLTKELKSQKELVKILHKALEAAQQEKRASS----AYLAAAEDKDRLELVRHKVR 367
Query: 292 SPIKVNQRTDKNEKGRQNLESVAKV 316
++ +R + E+ R++L A +
Sbjct: 368 QIAELGRRVEALEQERESLAHTASL 392
>gi|239757861 PREDICTED: similar to armadillo repeat containing,
X-linked 4 [Homo sapiens]
Length = 2382
Score = 40.8 bits (94), Expect = 0.004
Identities = 107/549 (19%), Positives = 186/549 (33%), Gaps = 68/549 (12%)
Query: 73 DRKVNERDVP--------KATISRYSSDDTLDRISDRNDAAKTYKANTLD--NQLTNRSM 122
D KV R P KA + S + L D++ A D + L+
Sbjct: 507 DAKVKNRGNPNAMTKAGAKANLRANSQVEALPDARDKSRGNPNVMAKVGDGTDMLSCTQP 566
Query: 123 SMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKK----RQSWFPPPPPGYNASSSTG 178
+ S++ L G NT+ A +K + Q P G +
Sbjct: 567 QLVASVQADTLSDGKIKVRGNVNTMPKEGAGVDMKAQGMAQSQGEALPNTRGKARGKAKA 626
Query: 179 TRRREPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNISEELDNLI 238
+ PG+ +P + V +P + D+R P ++ A++ + + L+
Sbjct: 627 KCKTGPGMDMKTCTQPQAGVKTPAEALLDSRVDGRGNPNATSKAGTKADQRVCGQ--PLV 684
Query: 239 KMNKSLNRNQGLDSLFRANP----KVEEREKRAKSLESLIYMSTR------TDKDGKGIQ 288
N G + + NP KV E S + +S + T KG
Sbjct: 685 VANPQGEALPGAKNKVKGNPHTVLKVGAGEGTTDSAQPEAVVSFQGEALLGTKNKVKGNP 744
Query: 289 SLGSPIKVNQ--------RTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKG 340
++ +V + + + KG L+S KV N S+ D V P+
Sbjct: 745 NVVLKAEVGEGAMGTAQLQIMASSKGEALLDSKNKVKGNSNAVSKAGAGTDTTGSVQPQI 804
Query: 341 HENTTGK--KDLDGLIKVDPETNKNITRGQSLDNLIKVTPEVKRSNQGS--KDLNNFIKV 396
N+ G+ I+ +P T N G + P+ ++QG N +K
Sbjct: 805 VANSQGEVLPGAKNKIRGNPTTVPNSGVGPYTTD--SARPQAVANSQGEVLPGAKNKVKA 862
Query: 397 YPGTEKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSP 456
E G ++ N + +N ++ +A + G+D + P
Sbjct: 863 NLNAVSKAEAGMGATGSVQPQAVANSHCETLPGAKNKVRGNWNAVSKAGAGMDTRGSAQP 922
Query: 457 KAVKNTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPS 516
+AV N+ G +V P N +K NP V+ +++ D + +P
Sbjct: 923 QAVANSQG--------EVLP----------GAKNKVKGNPNVVSKAGARE-DTVGSTQPQ 963
Query: 517 ALRNTNRDQNLENLIEVNSHVSENKNGSSNTGAKQ-----AGPQDTVVYTRTYVENSKSP 571
L ++ R E L + V N N S GA++ A PQ R + +++
Sbjct: 964 VLASSQR----ETLPGARNKVKGNSNVVSKAGAREDTMGSAQPQVVANSQRETLPGARNK 1019
Query: 572 KDGYQENIS 580
G IS
Sbjct: 1020 VKGNSNAIS 1028
>gi|55770895 ERBB2 interacting protein isoform 7 [Homo sapiens]
Length = 1302
Score = 40.8 bits (94), Expect = 0.004
Identities = 73/355 (20%), Positives = 143/355 (40%), Gaps = 55/355 (15%)
Query: 221 ETNRSAERNISEELDNLIKMNKSLNRNQGL---DSLFRANPKVEEREKRAKSLESLIYMS 277
ETN + R++ D + +N++ G+ +S KV+EREK +I S
Sbjct: 509 ETNEDSGRDLKPHEDQ-----QDINKDVGVKTSESTTTVKSKVDEREKY------MIGNS 557
Query: 278 TRTDKDGKGIQSLGS-PIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEV 336
+ + + S GS P+ N + +N K N + V + + ++ S++ E+
Sbjct: 558 VQKISEPEAEISPGSLPVTANMKASENLKHIVNHDDVFEESEELS-----SDEEMKMAEM 612
Query: 337 NPKGHENTTGKKDLDGLIKVDPETNKNITRGQSLDNLIKVTPEVKRSNQGSKDLNNFIKV 396
P E + + + L + K SL + + SNQ + + ++ ++
Sbjct: 613 RPPLIETSINQPKVVALSNNKKDDTKET---DSLSDEV-----THNSNQNNSNCSSPSRM 664
Query: 397 YPGTEKSTEGGQ--SLDSLIKVT--PERNRTNQGNQDLENLIKVIPSANKSSEQ------ 446
+T+ Q SL S +K T ++ Q +++ +L++ N S+E+
Sbjct: 665 SDSVSLNTDSSQDTSLCSPVKQTHIDINSKIRQEDENFNSLLQNGDILNSSTEEKFKAHD 724
Query: 447 -----------GLDEHINVSPKAVKNTDGKQDLDKLIKVNP---EIFTNNQRNQDLANLI 492
++E + + K+V +T D KL +N ++ TN+ ++
Sbjct: 725 KKDFNLPEYDLNVEERLVLIEKSVDSTATADDTHKLDHINMNLNKLITNDTFQPEIMERS 784
Query: 493 KVNPAVIRNNQSQDLDNLIKVKPSALRNTNRDQNLENLIEVNSHVSENKNGSSNT 547
K V+ + L K + L N N+ NLE++ +VN H E + T
Sbjct: 785 KTQDIVLGTSF---LSINSKEETEHLENGNKYPNLESVNKVNGHSEETSQSPNRT 836
>gi|8923909 ERBB2 interacting protein isoform 2 [Homo sapiens]
Length = 1371
Score = 40.8 bits (94), Expect = 0.004
Identities = 73/355 (20%), Positives = 143/355 (40%), Gaps = 55/355 (15%)
Query: 221 ETNRSAERNISEELDNLIKMNKSLNRNQGL---DSLFRANPKVEEREKRAKSLESLIYMS 277
ETN + R++ D + +N++ G+ +S KV+EREK +I S
Sbjct: 509 ETNEDSGRDLKPHEDQ-----QDINKDVGVKTSESTTTVKSKVDEREKY------MIGNS 557
Query: 278 TRTDKDGKGIQSLGS-PIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEV 336
+ + + S GS P+ N + +N K N + V + + ++ S++ E+
Sbjct: 558 VQKISEPEAEISPGSLPVTANMKASENLKHIVNHDDVFEESEELS-----SDEEMKMAEM 612
Query: 337 NPKGHENTTGKKDLDGLIKVDPETNKNITRGQSLDNLIKVTPEVKRSNQGSKDLNNFIKV 396
P E + + + L + K SL + + SNQ + + ++ ++
Sbjct: 613 RPPLIETSINQPKVVALSNNKKDDTKET---DSLSDEV-----THNSNQNNSNCSSPSRM 664
Query: 397 YPGTEKSTEGGQ--SLDSLIKVT--PERNRTNQGNQDLENLIKVIPSANKSSEQ------ 446
+T+ Q SL S +K T ++ Q +++ +L++ N S+E+
Sbjct: 665 SDSVSLNTDSSQDTSLCSPVKQTHIDINSKIRQEDENFNSLLQNGDILNSSTEEKFKAHD 724
Query: 447 -----------GLDEHINVSPKAVKNTDGKQDLDKLIKVNP---EIFTNNQRNQDLANLI 492
++E + + K+V +T D KL +N ++ TN+ ++
Sbjct: 725 KKDFNLPEYDLNVEERLVLIEKSVDSTATADDTHKLDHINMNLNKLITNDTFQPEIMERS 784
Query: 493 KVNPAVIRNNQSQDLDNLIKVKPSALRNTNRDQNLENLIEVNSHVSENKNGSSNT 547
K V+ + L K + L N N+ NLE++ +VN H E + T
Sbjct: 785 KTQDIVLGTSF---LSINSKEETEHLENGNKYPNLESVNKVNGHSEETSQSPNRT 836
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 39.3 bits (90), Expect = 0.012
Identities = 88/473 (18%), Positives = 180/473 (38%), Gaps = 27/473 (5%)
Query: 32 EVNKRRTFLQDNSWIKKRPEEEKDENYGRVVLNRHNSHDALDRKVNERDVPKATISRY-S 90
EV + R +QD S EKD+ + VV L+ +D T S Y S
Sbjct: 755 EVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKS 814
Query: 91 SDDTLDRISDRN-DAAKTYKANTLDNQLTNRSMSMFRSLEVTKLQPG-GSLNANTS-NTI 147
+D + D + YK +N+ N+ + S E K G+L S T
Sbjct: 815 TDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNL-SKEAQKFDSSLGALKTELSYKTQ 873
Query: 148 ASTSATTPVKKKRQSWFPPPPPGYNASSSTGTRRREPGVHPPIPPKPSSPVSSPNQLRQD 207
T V+++ N S+ T RE + + V + Q + D
Sbjct: 874 ELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDD 933
Query: 208 NRQIHPP--------KPGVYTETNRS--AERNISEELDNLIKMNKSLNRNQG-LDSLFRA 256
+Q+ K ++ N + + + L++L + +++N + +
Sbjct: 934 LKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSR 993
Query: 257 NPKVEER--EKRAKSLESLIYMSTRTDKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVA 314
N +EE E + + + ++ + + D + K Q+L + +K N+ ++ K ++
Sbjct: 994 NLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKN 1053
Query: 315 KVNARMNKTSRRSEDLDNATEVNPKGHENTTGKKDLDGLIKVDPETNKNITRGQSLDNLI 374
++ + E L + N E T ++ L+ + + + I Q ++ I
Sbjct: 1054 ELQQMLESVIAEKEQLKTDLKENI---EMTIENQEELRLLGDELKKQQEIV-AQEKNHAI 1109
Query: 375 KVTPEVKRSNQGSKDLNNFIKVYPGTEKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLI 434
K E+ R+ ++ +K EKS + + L+ V E + + ++ENL
Sbjct: 1110 KKEGELSRTCDRLAEVEEKLK-----EKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLK 1164
Query: 435 KVIPSANKSSEQGLDEHINVSPKAVKNTDGKQDLDKLIKVNPEIFTNNQRNQD 487
+ + + E E + ++ K +N + + + K KV E+ + + +D
Sbjct: 1165 NELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERD 1217
>gi|47578107 delangin isoform B [Homo sapiens]
Length = 2697
Score = 39.3 bits (90), Expect = 0.012
Identities = 78/361 (21%), Positives = 120/361 (33%), Gaps = 59/361 (16%)
Query: 133 LQPGGSLNANTSNTIASTSATTPVKKKRQSWFPPPPPGYNASSSTGTRRREPGVHPPIPP 192
L G +++ S T S S P + K+ + P G+ + P HP P
Sbjct: 545 LHQAGRVDSQASITQDSDSIKKPEEIKQCN---DAPVSVLQEDIVGSLKSTPENHPETPK 601
Query: 193 KPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNISEELDNLIKMNKSLNRNQGLDS 252
K S P S ++++Q ++ KP NR E SE
Sbjct: 602 KKSDPELSKSEMKQSESRLAESKP----NENRLVETKSSEN------------------- 638
Query: 253 LFRANPKVEEREKRAKSLESLIYMSTRTDKDGKGIQSLGSPIKVNQRTDKNEKGRQNLES 312
+ KVE + + K ES RT + + ++ P K N+ + K N ++
Sbjct: 639 --KLETKVETQTEELKQNES------RTTECKQNESTIVEP-KQNENRLSDTKPNDNKQN 689
Query: 313 VAKVNARMNKTSRRSEDLDNATEVNPK-------GHENTTGKKDLDGLIKVDPETNKNIT 365
N R T R E E P+ GH T +K DG PET K
Sbjct: 690 ----NGRSETTKSRPETPKQKGESRPETPKQKSDGHPETPKQKG-DG----RPETPKQ-- 738
Query: 366 RGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGTEKSTEGGQSLDSLIKVTPERNRTNQ 425
+G+S K E + + N P TEK E + +P
Sbjct: 739 KGESRPETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVSKHKQDTKSDSPRL----- 793
Query: 426 GNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVKNTDGKQDLDKLIKVNPEIFTNNQRN 485
+ +K P SE +H N + + D+ PE ++ RN
Sbjct: 794 -KSERAEALKQRPDGRSVSESLRRDHDNKQKSDDRGESERHRGDQSRVRRPETLRSSSRN 852
Query: 486 Q 486
+
Sbjct: 853 E 853
Score = 34.3 bits (77), Expect = 0.38
Identities = 115/593 (19%), Positives = 213/593 (35%), Gaps = 94/593 (15%)
Query: 16 MKSTTQG--TTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGRVVLNRHNSHDALD 73
+KST + T K++ E++K ++ + +P E + ++ +S + L+
Sbjct: 589 LKSTPENHPETPKKKSDPELSKSEMKQSESRLAESKPNENR-------LVETKSSENKLE 641
Query: 74 RKVN------ERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNRSMSMFRS 127
KV +++ + T + + ++ + N + T K N DN+ N +S
Sbjct: 642 TKVETQTEELKQNESRTTECKQNESTIVEPKQNENRLSDT-KPN--DNKQNNGRSETTKS 698
Query: 128 LEVTKLQPGGSLNANTSNTIASTSATTPVKKKRQSWFPPPPPGYNASSSTGTRRREPGVH 187
T Q G S T S P K++ P P S T +++
Sbjct: 699 RPETPKQKGES----RPETPKQKSDGHPETPKQKGDGRPETPKQKGESRPETPKQKNEGR 754
Query: 188 PPIPP----------KPSSPVSSP-NQLRQDNRQIHPPKPGVYTET--NRSAERNISEEL 234
P P KPS+ ++ +QD + P E R R++SE L
Sbjct: 755 PETPKHRHDNRRDSGKPSTEKKPEVSKHKQDTKSDSPRLKSERAEALKQRPDGRSVSESL 814
Query: 235 DNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRTDKDGKGIQSLGSPI 294
NK + ++G R + + R +R ++L S + ++ GI+S S
Sbjct: 815 RR-DHDNKQKSDDRGESERHRGD---QSRVRRPETLRS-------SSRNEHGIKSDSSKT 863
Query: 295 KVNQRTDKNEKG--RQNLESVAKVN------ARMNKTSRRSEDLDNATEVNPKGHENTTG 346
+R ++E G R+ S + + + +++ D K + T G
Sbjct: 864 DKLERKHRHESGDSRERPSSGEQKSRPDSPRVKQGDSNKSRSDKLGFKSPTSKDDKRTEG 923
Query: 347 KKDLDGLIKVDPETNKNIT------RGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGT 400
K K P+ R +L N V P++KR G+ V T
Sbjct: 924 NKSKVDTNKAHPDNKAEFPSYLLGGRSGALKNF--VIPKIKRDKDGN--------VTQET 973
Query: 401 EKSTEGGQSLDSLIKVTPERNRTNQGNQ--------DLENLIKVIPSANKSSEQGLDEHI 452
+K G+ D + K+ + N+G + L+++ K+I S L
Sbjct: 974 KKMEMKGEPKDKVEKIGLVED-LNKGAKPVVVLQKLSLDDVQKLIKDREDKSRSSLKP-- 1030
Query: 453 NVSPKAVKNTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVN----------PAVIRNN 502
+ K K+ G D L ++ PE+ + L +K+N P +
Sbjct: 1031 -IKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVNEKPKYAEIS 1089
Query: 503 QSQDLDNLIKVKPSALRNTNRDQNLENLIEVNSHVS--ENKNGSSNTGAKQAG 553
+D D+ + S R+ D E + S ++G S+ G + +G
Sbjct: 1090 SDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHEGRRSSG 1142
>gi|47578105 delangin isoform A [Homo sapiens]
Length = 2804
Score = 39.3 bits (90), Expect = 0.012
Identities = 78/361 (21%), Positives = 120/361 (33%), Gaps = 59/361 (16%)
Query: 133 LQPGGSLNANTSNTIASTSATTPVKKKRQSWFPPPPPGYNASSSTGTRRREPGVHPPIPP 192
L G +++ S T S S P + K+ + P G+ + P HP P
Sbjct: 545 LHQAGRVDSQASITQDSDSIKKPEEIKQCN---DAPVSVLQEDIVGSLKSTPENHPETPK 601
Query: 193 KPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNISEELDNLIKMNKSLNRNQGLDS 252
K S P S ++++Q ++ KP NR E SE
Sbjct: 602 KKSDPELSKSEMKQSESRLAESKP----NENRLVETKSSEN------------------- 638
Query: 253 LFRANPKVEEREKRAKSLESLIYMSTRTDKDGKGIQSLGSPIKVNQRTDKNEKGRQNLES 312
+ KVE + + K ES RT + + ++ P K N+ + K N ++
Sbjct: 639 --KLETKVETQTEELKQNES------RTTECKQNESTIVEP-KQNENRLSDTKPNDNKQN 689
Query: 313 VAKVNARMNKTSRRSEDLDNATEVNPK-------GHENTTGKKDLDGLIKVDPETNKNIT 365
N R T R E E P+ GH T +K DG PET K
Sbjct: 690 ----NGRSETTKSRPETPKQKGESRPETPKQKSDGHPETPKQKG-DG----RPETPKQ-- 738
Query: 366 RGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGTEKSTEGGQSLDSLIKVTPERNRTNQ 425
+G+S K E + + N P TEK E + +P
Sbjct: 739 KGESRPETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVSKHKQDTKSDSPRL----- 793
Query: 426 GNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVKNTDGKQDLDKLIKVNPEIFTNNQRN 485
+ +K P SE +H N + + D+ PE ++ RN
Sbjct: 794 -KSERAEALKQRPDGRSVSESLRRDHDNKQKSDDRGESERHRGDQSRVRRPETLRSSSRN 852
Query: 486 Q 486
+
Sbjct: 853 E 853
Score = 34.3 bits (77), Expect = 0.38
Identities = 115/593 (19%), Positives = 213/593 (35%), Gaps = 94/593 (15%)
Query: 16 MKSTTQG--TTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGRVVLNRHNSHDALD 73
+KST + T K++ E++K ++ + +P E + ++ +S + L+
Sbjct: 589 LKSTPENHPETPKKKSDPELSKSEMKQSESRLAESKPNENR-------LVETKSSENKLE 641
Query: 74 RKVN------ERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNRSMSMFRS 127
KV +++ + T + + ++ + N + T K N DN+ N +S
Sbjct: 642 TKVETQTEELKQNESRTTECKQNESTIVEPKQNENRLSDT-KPN--DNKQNNGRSETTKS 698
Query: 128 LEVTKLQPGGSLNANTSNTIASTSATTPVKKKRQSWFPPPPPGYNASSSTGTRRREPGVH 187
T Q G S T S P K++ P P S T +++
Sbjct: 699 RPETPKQKGES----RPETPKQKSDGHPETPKQKGDGRPETPKQKGESRPETPKQKNEGR 754
Query: 188 PPIPP----------KPSSPVSSP-NQLRQDNRQIHPPKPGVYTET--NRSAERNISEEL 234
P P KPS+ ++ +QD + P E R R++SE L
Sbjct: 755 PETPKHRHDNRRDSGKPSTEKKPEVSKHKQDTKSDSPRLKSERAEALKQRPDGRSVSESL 814
Query: 235 DNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRTDKDGKGIQSLGSPI 294
NK + ++G R + + R +R ++L S + ++ GI+S S
Sbjct: 815 RR-DHDNKQKSDDRGESERHRGD---QSRVRRPETLRS-------SSRNEHGIKSDSSKT 863
Query: 295 KVNQRTDKNEKG--RQNLESVAKVN------ARMNKTSRRSEDLDNATEVNPKGHENTTG 346
+R ++E G R+ S + + + +++ D K + T G
Sbjct: 864 DKLERKHRHESGDSRERPSSGEQKSRPDSPRVKQGDSNKSRSDKLGFKSPTSKDDKRTEG 923
Query: 347 KKDLDGLIKVDPETNKNIT------RGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGT 400
K K P+ R +L N V P++KR G+ V T
Sbjct: 924 NKSKVDTNKAHPDNKAEFPSYLLGGRSGALKNF--VIPKIKRDKDGN--------VTQET 973
Query: 401 EKSTEGGQSLDSLIKVTPERNRTNQGNQ--------DLENLIKVIPSANKSSEQGLDEHI 452
+K G+ D + K+ + N+G + L+++ K+I S L
Sbjct: 974 KKMEMKGEPKDKVEKIGLVED-LNKGAKPVVVLQKLSLDDVQKLIKDREDKSRSSLKP-- 1030
Query: 453 NVSPKAVKNTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVN----------PAVIRNN 502
+ K K+ G D L ++ PE+ + L +K+N P +
Sbjct: 1031 -IKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVNEKPKYAEIS 1089
Query: 503 QSQDLDNLIKVKPSALRNTNRDQNLENLIEVNSHVS--ENKNGSSNTGAKQAG 553
+D D+ + S R+ D E + S ++G S+ G + +G
Sbjct: 1090 SDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHEGRRSSG 1142
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 38.9 bits (89), Expect = 0.015
Identities = 72/337 (21%), Positives = 131/337 (38%), Gaps = 42/337 (12%)
Query: 176 STGTRRREPGVHP-PIPPKP-SSPVSSPNQLRQDNRQIHPPKPGVYTETNRS----AERN 229
ST T+R++P VH + KP SS VS+ N++I K TE +ERN
Sbjct: 54 STDTKRQKPSVHSRQLVSKPLSSSVSN-------NKRIVSTKGKSATEYKNEEYQRSERN 106
Query: 230 ISEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKS------------LESLIYMS 277
+ D I+++ S +R + + + + E+RAKS ++ S
Sbjct: 107 KRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRS 166
Query: 278 TRTDKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVN 337
+++ K+ + GS + +E+G V + + ED + EV+
Sbjct: 167 SQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVD 226
Query: 338 PKGHENTTGKKDLDGLIKVDPETNKNITRGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVY 397
G E +++ + + + E + R Q + T + S+ GS+ ++
Sbjct: 227 EDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDT-RSEASDSGSESVS------ 279
Query: 398 PGTEKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPK 457
T+ S G D + ER R + + + S + + + E ++ S +
Sbjct: 280 -FTDGSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASESYAGSEKKHEKLSSSVR 338
Query: 458 AVKNTDGKQDLDKLIKVNPE-----IFTNNQRNQDLA 489
AV+ K KL V + I +NN N LA
Sbjct: 339 AVR----KDQTSKLKYVLQDARFFLIKSNNHENVSLA 371
>gi|228480221 four and a half LIM domains 1 isoform 4 [Homo sapiens]
Length = 194
Score = 38.1 bits (87), Expect = 0.026
Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Query: 601 CTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLEN 639
C CRKP+G ++K + + + H TCF+C C PL N
Sbjct: 40 CVECRKPIGADSKEVHYKNRFW-HDTCFRCAKCLHPLAN 77
>gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 38.1 bits (87), Expect = 0.026
Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Query: 601 CTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLEN 639
C CRKP+G ++K + + + H TCF+C C PL N
Sbjct: 40 CVECRKPIGADSKEVHYKNRFW-HDTCFRCAKCLHPLAN 77
>gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens]
Length = 323
Score = 38.1 bits (87), Expect = 0.026
Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Query: 601 CTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLEN 639
C CRKP+G ++K + + + H TCF+C C PL N
Sbjct: 40 CVECRKPIGADSKEVHYKNRFW-HDTCFRCAKCLHPLAN 77
>gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 38.1 bits (87), Expect = 0.026
Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Query: 601 CTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLEN 639
C CRKP+G ++K + + + H TCF+C C PL N
Sbjct: 40 CVECRKPIGADSKEVHYKNRFW-HDTCFRCAKCLHPLAN 77
>gi|11415052 retinoid X receptor, beta [Homo sapiens]
Length = 533
Score = 38.1 bits (87), Expect = 0.026
Identities = 27/70 (38%), Positives = 34/70 (48%), Gaps = 13/70 (18%)
Query: 135 PGGSLNANTSNTIASTSATTPVKKKRQSWFPPPPPGYN---ASSSTGTRRREPGVHPPIP 191
PG L +T+ ++ + A P PPPP G SSS G+ PG+ PP P
Sbjct: 101 PGPPLPPSTAPSLGGSGAPPPPP------MPPPPLGSPFPVISSSMGS----PGLPPPAP 150
Query: 192 PKPSSPVSSP 201
P S PVSSP
Sbjct: 151 PGFSGPVSSP 160
Score = 30.8 bits (68), Expect = 4.2
Identities = 16/37 (43%), Positives = 17/37 (45%), Gaps = 1/37 (2%)
Query: 165 PPPPPGYNASSSTGTRRREPGVHPPIPPKPSSPVSSP 201
PP PPG ST G PP PP P P+ SP
Sbjct: 97 PPSPPGPPLPPSTAPSLGGSGAPPP-PPMPPPPLGSP 132
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 38.1 bits (87), Expect = 0.026
Identities = 48/194 (24%), Positives = 71/194 (36%), Gaps = 31/194 (15%)
Query: 48 KRPEEEKDENYGRVVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKT 107
K PE + YG V N ++ + K ++ + KA I S+ + + D
Sbjct: 165 KNPEITTNRFYGPQVNNISHTKEKKKGKAKKKRLTKADIGTPSNFQHIGHVGW--DPNTG 222
Query: 108 YKANTLDNQLTNR------SMSMFRSLEVTK-----LQPGGSLNANTSNTIASTSATTPV 156
+ N LD +L N S + + E +K ++ G + A + A P
Sbjct: 223 FDLNNLDPELKNLFDMCGISEAQLKDRETSKVIYDFIEKTGGVEAVKNEL--RRQAPPPP 280
Query: 157 KKKRQSWFPPPPPGYNASSSTGTRR----------REPGVHPPIPP--KPSSPVSSPNQL 204
R PPPPP +N+ R R P PP PP +PS V P
Sbjct: 281 PPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPP--- 337
Query: 205 RQDNRQIHPPKPGV 218
NR PP P +
Sbjct: 338 -PPNRMYPPPPPAL 350
Score = 34.7 bits (78), Expect = 0.29
Identities = 20/58 (34%), Positives = 25/58 (43%), Gaps = 12/58 (20%)
Query: 164 FPPPPPGYNASSSTGTRRREP---GVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGV 218
+PPPPP +S+ +G P GV P PP P P P PP PG+
Sbjct: 343 YPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGP---------PPPPGL 391
>gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]
Length = 309
Score = 38.1 bits (87), Expect = 0.026
Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Query: 601 CTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLEN 639
C CRKP+G ++K + + + H TCF+C C PL N
Sbjct: 69 CVECRKPIGADSKEVHYKNRFW-HDTCFRCAKCLHPLAN 106
>gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]
Length = 296
Score = 38.1 bits (87), Expect = 0.026
Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Query: 601 CTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLEN 639
C CRKP+G ++K + + + H TCF+C C PL N
Sbjct: 56 CVECRKPIGADSKEVHYKNRFW-HDTCFRCAKCLHPLAN 93
>gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 38.1 bits (87), Expect = 0.026
Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Query: 601 CTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLEN 639
C CRKP+G ++K + + + H TCF+C C PL N
Sbjct: 40 CVECRKPIGADSKEVHYKNRFW-HDTCFRCAKCLHPLAN 77
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.126 0.356
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,129,377
Number of Sequences: 37866
Number of extensions: 1391642
Number of successful extensions: 8188
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 46
Number of HSP's successfully gapped in prelim test: 372
Number of HSP's that attempted gapping in prelim test: 7001
Number of HSP's gapped (non-prelim): 1211
length of query: 668
length of database: 18,247,518
effective HSP length: 109
effective length of query: 559
effective length of database: 14,120,124
effective search space: 7893149316
effective search space used: 7893149316
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.