Guide to the Human Genome
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Search of human proteins with 237820624

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|237820624 pleckstrin homology domain containing, family N
member 1 isoform b [Homo sapiens]
         (576 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|237820624 pleckstrin homology domain containing, family N mem...  1188   0.0  
gi|237820622 pleckstrin homology domain containing, family N mem...  1129   0.0  
gi|166064038 PAK-interacting exchange factor beta isoform a [Hom...    68   3e-11
gi|166064036 PAK-interacting exchange factor beta isoform d [Hom...    68   3e-11
gi|166064034 PAK-interacting exchange factor beta isoform c [Hom...    68   3e-11
gi|22027528 PAK-interacting exchange factor beta isoform b [Homo...    68   3e-11
gi|4505573 PAK-interacting exchange factor beta isoform a [Homo ...    68   3e-11
gi|22027525 Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo...    50   7e-06
gi|169168458 PREDICTED: hypothetical protein [Homo sapiens]            48   3e-05
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              46   8e-05
gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapi...    44   3e-04
gi|28559039 mediator complex subunit 1 [Homo sapiens]                  44   4e-04
gi|157311635 FAM83H [Homo sapiens]                                     42   0.001
gi|31324577 molecule interacting with Rab13 [Homo sapiens]             42   0.001
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   42   0.002
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   42   0.002
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   42   0.002
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    42   0.002
gi|221139926 NHS-like 1 [Homo sapiens]                                 41   0.003
gi|41281612 zinc finger protein 828 [Homo sapiens]                     41   0.003
gi|151301154 mucin 6, gastric [Homo sapiens]                           41   0.003
gi|23510413 sorting nexin 26 [Homo sapiens]                            41   0.003
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    41   0.003
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    41   0.003
gi|187937179 apoptosis-associated tyrosine kinase [Homo sapiens]       40   0.004
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]        40   0.006
gi|209862845 nuclear factor of activated T-cells, cytoplasmic, c...    40   0.008
gi|27886563 nuclear factor of activated T-cells, cytoplasmic, ca...    40   0.008
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re...    40   0.008
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re...    40   0.008

>gi|237820624 pleckstrin homology domain containing, family N member
           1 isoform b [Homo sapiens]
          Length = 576

 Score = 1188 bits (3073), Expect = 0.0
 Identities = 576/576 (100%), Positives = 576/576 (100%)

Query: 1   MGNSHCVPQAPRRLRASFSRKPSLKGNREDSARMSAGLPGPEAARSGDAAANKLFHYIPG 60
           MGNSHCVPQAPRRLRASFSRKPSLKGNREDSARMSAGLPGPEAARSGDAAANKLFHYIPG
Sbjct: 1   MGNSHCVPQAPRRLRASFSRKPSLKGNREDSARMSAGLPGPEAARSGDAAANKLFHYIPG 60

Query: 61  TDILDLENQRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELF 120
           TDILDLENQRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELF
Sbjct: 61  TDILDLENQRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELF 120

Query: 121 PAHLYFQAHGSEGLTFQGLLPLTELSVCPLEGSREHAFQITGPLPAPLLVLCPSRAELDR 180
           PAHLYFQAHGSEGLTFQGLLPLTELSVCPLEGSREHAFQITGPLPAPLLVLCPSRAELDR
Sbjct: 121 PAHLYFQAHGSEGLTFQGLLPLTELSVCPLEGSREHAFQITGPLPAPLLVLCPSRAELDR 180

Query: 181 WLYHLEKQTALLGGPRRCHSAPPQGSCGDELPWTLQRRLTRLRTASGHEPGGSAVCASRV 240
           WLYHLEKQTALLGGPRRCHSAPPQGSCGDELPWTLQRRLTRLRTASGHEPGGSAVCASRV
Sbjct: 181 WLYHLEKQTALLGGPRRCHSAPPQGSCGDELPWTLQRRLTRLRTASGHEPGGSAVCASRV 240

Query: 241 KLQHLPAQEQWDRLLVLYPTSLAIFSEELDGLCFKGELPLRAVHINLEEKEKQIRSFLIE 300
           KLQHLPAQEQWDRLLVLYPTSLAIFSEELDGLCFKGELPLRAVHINLEEKEKQIRSFLIE
Sbjct: 241 KLQHLPAQEQWDRLLVLYPTSLAIFSEELDGLCFKGELPLRAVHINLEEKEKQIRSFLIE 300

Query: 301 GPLINTIRVVCASYEDYGHWLLCLRAVTHREGAPPLPGAESFPGSQVMGSGRGSLSSGGQ 360
           GPLINTIRVVCASYEDYGHWLLCLRAVTHREGAPPLPGAESFPGSQVMGSGRGSLSSGGQ
Sbjct: 301 GPLINTIRVVCASYEDYGHWLLCLRAVTHREGAPPLPGAESFPGSQVMGSGRGSLSSGGQ 360

Query: 361 TSWDSGCLAPPSTRTSHSLPESSVPSTVGCSSQHTPLHRLSLESSPDAPDHTSETSHSPL 420
           TSWDSGCLAPPSTRTSHSLPESSVPSTVGCSSQHTPLHRLSLESSPDAPDHTSETSHSPL
Sbjct: 361 TSWDSGCLAPPSTRTSHSLPESSVPSTVGCSSQHTPLHRLSLESSPDAPDHTSETSHSPL 420

Query: 421 YADPYTPPATSHRRVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPA 480
           YADPYTPPATSHRRVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPA
Sbjct: 421 YADPYTPPATSHRRVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPA 480

Query: 481 GPYLLSKKGALQSRAAQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRS 540
           GPYLLSKKGALQSRAAQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRS
Sbjct: 481 GPYLLSKKGALQSRAAQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRS 540

Query: 541 RDPGYDHLWDETLSSSHQKCPQLGGPEASGGLVQWI 576
           RDPGYDHLWDETLSSSHQKCPQLGGPEASGGLVQWI
Sbjct: 541 RDPGYDHLWDETLSSSHQKCPQLGGPEASGGLVQWI 576


>gi|237820622 pleckstrin homology domain containing, family N member
           1 isoform a [Homo sapiens]
          Length = 611

 Score = 1129 bits (2920), Expect = 0.0
 Identities = 564/623 (90%), Positives = 564/623 (90%), Gaps = 59/623 (9%)

Query: 1   MGNSHCVPQAPRRLRASFSRKPSLKGNREDSARMSAGLPGPEAARSGDAAANKLFHYIPG 60
           MGNSHCVPQAPRRLRASFSRKPSLKGNREDSARMSAGLPGPEAARSGDAAANKLFHYIPG
Sbjct: 1   MGNSHCVPQAPRRLRASFSRKPSLKGNREDSARMSAGLPGPEAARSGDAAANKLFHYIPG 60

Query: 61  TDILDLENQRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELF 120
           TDILDLENQRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELF
Sbjct: 61  TDILDLENQRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELF 120

Query: 121 PAHLYFQAHGSEGLTFQGLLPLTELSVCPLEGSREHAFQITGPLPAPLLVLCPSRAELDR 180
           PAHLYFQAHGSEGLTFQGLLPLTELSVCPLEGSREHAFQITGPLPAPLLVLCPSRAELDR
Sbjct: 121 PAHLYFQAHGSEGLTFQGLLPLTELSVCPLEGSREHAFQITGPLPAPLLVLCPSRAELDR 180

Query: 181 WLYHLEKQTALLGGPRRCHSAPPQGSCGDELPWTLQRRLTRLRTASGHEPGGSAVCASRV 240
           WLYHLEKQTALLGGPRRCHSAPP            QRRLTRLRTASGHEPGGSAVCASRV
Sbjct: 181 WLYHLEKQTALLGGPRRCHSAPP------------QRRLTRLRTASGHEPGGSAVCASRV 228

Query: 241 KLQHLPAQEQWDRLLVLYPTSLAIFSEELDGLCFKGELPLRAVHINLEEKEKQIRSFLIE 300
           KLQHLPAQEQWDRLLVLYPTSLAIFSEELDGLCFKGELPLRAVHINLEEKEKQIRSFLIE
Sbjct: 229 KLQHLPAQEQWDRLLVLYPTSLAIFSEELDGLCFKGELPLRAVHINLEEKEKQIRSFLIE 288

Query: 301 GPLINTIRVVCASYEDYGHWLLCLRAVTHREGAPPLPGAESFPGSQVMGSGRGSLSSGGQ 360
           GPLINTIRVVCASYEDYGHWLLCLRAVTHREGAPPLPGAESFPGSQVMGSGRGSLSSGGQ
Sbjct: 289 GPLINTIRVVCASYEDYGHWLLCLRAVTHREGAPPLPGAESFPGSQVMGSGRGSLSSGGQ 348

Query: 361 TSWDSGCLAPPSTRTSHSLPESSVPSTVGCSSQHTP------------------------ 396
           TSWDSGCLAPPSTRTSHSLPESSVPSTVGCSSQHTP                        
Sbjct: 349 TSWDSGCLAPPSTRTSHSLPESSVPSTVGCSSQHTPDQANSDRASIGRRRTELRRSGSSR 408

Query: 397 -----------------------LHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHR 433
                                  LHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHR
Sbjct: 409 SPGSKARAEGRGPVTPLHLDLTQLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHR 468

Query: 434 RVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQS 493
           RVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQS
Sbjct: 469 RVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQS 528

Query: 494 RAAQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRSRDPGYDHLWDETL 553
           RAAQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRSRDPGYDHLWDETL
Sbjct: 529 RAAQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRSRDPGYDHLWDETL 588

Query: 554 SSSHQKCPQLGGPEASGGLVQWI 576
           SSSHQKCPQLGGPEASGGLVQWI
Sbjct: 589 SSSHQKCPQLGGPEASGGLVQWI 611


>gi|166064038 PAK-interacting exchange factor beta isoform a [Homo
           sapiens]
          Length = 646

 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 7/141 (4%)

Query: 69  QRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELFPAHLYFQA 128
           +R+ LE   L+   +      ++ LG V + ++V ++   S++ ++ YL LFP  L   +
Sbjct: 275 KRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLS 334

Query: 129 HGSE--GLTFQGLLPLTELSVCPLEGSREH--AFQITGPLPAPLLVLCPSRAELDRWLYH 184
                 G  +QG LP T +++  LE S  H  AF+I+G +   +LV C ++ +L  W+ H
Sbjct: 335 ASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLQEWVEH 394

Query: 185 LEKQTAL--LGGPR-RCHSAP 202
           L+KQT +  +G P  + HS P
Sbjct: 395 LQKQTKVTSVGNPTIKPHSVP 415



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 51/203 (25%), Positives = 84/203 (41%), Gaps = 38/203 (18%)

Query: 232 GSAVCASRVKLQHLPAQEQWDRLLVLYPTSLAIFSEE--LDGLCFKGELPLRAVHIN-LE 288
           G+    S+V +Q   ++E+ +R L+L+P  L + S    + G  ++G+LP   + I  LE
Sbjct: 300 GNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLSASPRMSGFIYQGKLPTTGMTITKLE 359

Query: 289 EKEKQIRSFLIEGPLINTIRVVCASYEDYGHWLLCLRAVTHREGAPPLPGAESFPGSQVM 348
           + E    +F I G +I  I V C + +D   W+  L+  T                 +V 
Sbjct: 360 DSENHRNAFEISGSMIERILVSCNNQQDLQEWVEHLQKQT-----------------KVT 402

Query: 349 GSGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSV-PSTVGCSSQHTPLHRLSLESSPD 407
             G  ++               P +  SH+LP   V PS+    S+  PL   +  + P 
Sbjct: 403 SVGNPTIK--------------PHSVPSHTLPSHPVTPSSKHADSKPAPL-TPAYHTLPH 447

Query: 408 APDHTSETSHSPLYADPYTPPAT 430
              H   T H+ +   P  PP T
Sbjct: 448 PSHH--GTPHTTINWGPLEPPKT 468


>gi|166064036 PAK-interacting exchange factor beta isoform d [Homo
           sapiens]
          Length = 753

 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 7/141 (4%)

Query: 69  QRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELFPAHLYFQA 128
           +R+ LE   L+   +      ++ LG V + ++V ++   S++ ++ YL LFP  L   +
Sbjct: 403 KRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLS 462

Query: 129 HGSE--GLTFQGLLPLTELSVCPLEGSREH--AFQITGPLPAPLLVLCPSRAELDRWLYH 184
                 G  +QG LP T +++  LE S  H  AF+I+G +   +LV C ++ +L  W+ H
Sbjct: 463 ASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLQEWVEH 522

Query: 185 LEKQTAL--LGGPR-RCHSAP 202
           L+KQT +  +G P  + HS P
Sbjct: 523 LQKQTKVTSVGNPTIKPHSVP 543



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 51/203 (25%), Positives = 84/203 (41%), Gaps = 38/203 (18%)

Query: 232 GSAVCASRVKLQHLPAQEQWDRLLVLYPTSLAIFSEE--LDGLCFKGELPLRAVHIN-LE 288
           G+    S+V +Q   ++E+ +R L+L+P  L + S    + G  ++G+LP   + I  LE
Sbjct: 428 GNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLSASPRMSGFIYQGKLPTTGMTITKLE 487

Query: 289 EKEKQIRSFLIEGPLINTIRVVCASYEDYGHWLLCLRAVTHREGAPPLPGAESFPGSQVM 348
           + E    +F I G +I  I V C + +D   W+  L+  T                 +V 
Sbjct: 488 DSENHRNAFEISGSMIERILVSCNNQQDLQEWVEHLQKQT-----------------KVT 530

Query: 349 GSGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSV-PSTVGCSSQHTPLHRLSLESSPD 407
             G  ++               P +  SH+LP   V PS+    S+  PL   +  + P 
Sbjct: 531 SVGNPTIK--------------PHSVPSHTLPSHPVTPSSKHADSKPAPL-TPAYHTLPH 575

Query: 408 APDHTSETSHSPLYADPYTPPAT 430
              H   T H+ +   P  PP T
Sbjct: 576 PSHH--GTPHTTINWGPLEPPKT 596


>gi|166064034 PAK-interacting exchange factor beta isoform c [Homo
           sapiens]
          Length = 803

 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 7/141 (4%)

Query: 69  QRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELFPAHLYFQA 128
           +R+ LE   L+   +      ++ LG V + ++V ++   S++ ++ YL LFP  L   +
Sbjct: 453 KRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLS 512

Query: 129 HGSE--GLTFQGLLPLTELSVCPLEGSREH--AFQITGPLPAPLLVLCPSRAELDRWLYH 184
                 G  +QG LP T +++  LE S  H  AF+I+G +   +LV C ++ +L  W+ H
Sbjct: 513 ASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLQEWVEH 572

Query: 185 LEKQTAL--LGGPR-RCHSAP 202
           L+KQT +  +G P  + HS P
Sbjct: 573 LQKQTKVTSVGNPTIKPHSVP 593



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 51/203 (25%), Positives = 84/203 (41%), Gaps = 38/203 (18%)

Query: 232 GSAVCASRVKLQHLPAQEQWDRLLVLYPTSLAIFSEE--LDGLCFKGELPLRAVHIN-LE 288
           G+    S+V +Q   ++E+ +R L+L+P  L + S    + G  ++G+LP   + I  LE
Sbjct: 478 GNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLSASPRMSGFIYQGKLPTTGMTITKLE 537

Query: 289 EKEKQIRSFLIEGPLINTIRVVCASYEDYGHWLLCLRAVTHREGAPPLPGAESFPGSQVM 348
           + E    +F I G +I  I V C + +D   W+  L+  T                 +V 
Sbjct: 538 DSENHRNAFEISGSMIERILVSCNNQQDLQEWVEHLQKQT-----------------KVT 580

Query: 349 GSGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSV-PSTVGCSSQHTPLHRLSLESSPD 407
             G  ++               P +  SH+LP   V PS+    S+  PL   +  + P 
Sbjct: 581 SVGNPTIK--------------PHSVPSHTLPSHPVTPSSKHADSKPAPL-TPAYHTLPH 625

Query: 408 APDHTSETSHSPLYADPYTPPAT 430
              H   T H+ +   P  PP T
Sbjct: 626 PSHH--GTPHTTINWGPLEPPKT 646


>gi|22027528 PAK-interacting exchange factor beta isoform b [Homo
           sapiens]
          Length = 782

 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 7/141 (4%)

Query: 69  QRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELFPAHLYFQA 128
           +R+ LE   L+   +      ++ LG V + ++V ++   S++ ++ YL LFP  L   +
Sbjct: 432 KRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLS 491

Query: 129 HGSE--GLTFQGLLPLTELSVCPLEGSREH--AFQITGPLPAPLLVLCPSRAELDRWLYH 184
                 G  +QG LP T +++  LE S  H  AF+I+G +   +LV C ++ +L  W+ H
Sbjct: 492 ASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLQEWVEH 551

Query: 185 LEKQTAL--LGGPR-RCHSAP 202
           L+KQT +  +G P  + HS P
Sbjct: 552 LQKQTKVTSVGNPTIKPHSVP 572



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 51/203 (25%), Positives = 84/203 (41%), Gaps = 38/203 (18%)

Query: 232 GSAVCASRVKLQHLPAQEQWDRLLVLYPTSLAIFSEE--LDGLCFKGELPLRAVHIN-LE 288
           G+    S+V +Q   ++E+ +R L+L+P  L + S    + G  ++G+LP   + I  LE
Sbjct: 457 GNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLSASPRMSGFIYQGKLPTTGMTITKLE 516

Query: 289 EKEKQIRSFLIEGPLINTIRVVCASYEDYGHWLLCLRAVTHREGAPPLPGAESFPGSQVM 348
           + E    +F I G +I  I V C + +D   W+  L+  T                 +V 
Sbjct: 517 DSENHRNAFEISGSMIERILVSCNNQQDLQEWVEHLQKQT-----------------KVT 559

Query: 349 GSGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSV-PSTVGCSSQHTPLHRLSLESSPD 407
             G  ++               P +  SH+LP   V PS+    S+  PL   +  + P 
Sbjct: 560 SVGNPTIK--------------PHSVPSHTLPSHPVTPSSKHADSKPAPL-TPAYHTLPH 604

Query: 408 APDHTSETSHSPLYADPYTPPAT 430
              H   T H+ +   P  PP T
Sbjct: 605 PSHH--GTPHTTINWGPLEPPKT 625


>gi|4505573 PAK-interacting exchange factor beta isoform a [Homo
           sapiens]
          Length = 646

 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 44/141 (31%), Positives = 76/141 (53%), Gaps = 7/141 (4%)

Query: 69  QRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELFPAHLYFQA 128
           +R+ LE   L+   +      ++ LG V + ++V ++   S++ ++ YL LFP  L   +
Sbjct: 275 KRKELELQILTEAIRNWEGDDIKTLGNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLS 334

Query: 129 HGSE--GLTFQGLLPLTELSVCPLEGSREH--AFQITGPLPAPLLVLCPSRAELDRWLYH 184
                 G  +QG LP T +++  LE S  H  AF+I+G +   +LV C ++ +L  W+ H
Sbjct: 335 ASPRMSGFIYQGKLPTTGMTITKLEDSENHRNAFEISGSMIERILVSCNNQQDLQEWVEH 394

Query: 185 LEKQTAL--LGGPR-RCHSAP 202
           L+KQT +  +G P  + HS P
Sbjct: 395 LQKQTKVTSVGNPTIKPHSVP 415



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 51/203 (25%), Positives = 84/203 (41%), Gaps = 38/203 (18%)

Query: 232 GSAVCASRVKLQHLPAQEQWDRLLVLYPTSLAIFSEE--LDGLCFKGELPLRAVHIN-LE 288
           G+    S+V +Q   ++E+ +R L+L+P  L + S    + G  ++G+LP   + I  LE
Sbjct: 300 GNVTYMSQVLIQCAGSEEKNERYLLLFPNVLLMLSASPRMSGFIYQGKLPTTGMTITKLE 359

Query: 289 EKEKQIRSFLIEGPLINTIRVVCASYEDYGHWLLCLRAVTHREGAPPLPGAESFPGSQVM 348
           + E    +F I G +I  I V C + +D   W+  L+  T                 +V 
Sbjct: 360 DSENHRNAFEISGSMIERILVSCNNQQDLQEWVEHLQKQT-----------------KVT 402

Query: 349 GSGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSV-PSTVGCSSQHTPLHRLSLESSPD 407
             G  ++               P +  SH+LP   V PS+    S+  PL   +  + P 
Sbjct: 403 SVGNPTIK--------------PHSVPSHTLPSHPVTPSSKHADSKPAPL-TPAYHTLPH 447

Query: 408 APDHTSETSHSPLYADPYTPPAT 430
              H   T H+ +   P  PP T
Sbjct: 448 PSHH--GTPHTTINWGPLEPPKT 468


>gi|22027525 Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo
           sapiens]
          Length = 776

 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 52/213 (24%), Positives = 85/213 (39%), Gaps = 25/213 (11%)

Query: 232 GSAVCASRVKLQHLPAQEQWDRLLVLYPTSLAIFSEE--LDGLCFKGELPLRAVHIN-LE 288
           G+ +  S+V +Q+   +E+ +R L+L+   L + S    + G  ++G++P+    +  L+
Sbjct: 448 GNVIFMSQVMVQYGACEEKEERYLMLFSNVLIMLSASPRMSGFIYQGKIPIAGTVVTRLD 507

Query: 289 EKEKQIRSFLIEGPLINTIRVVCASYEDYGHWLLCLRAVTHREGAPPLPGAESFPGSQVM 348
           E E    +F I G  +  I V C + +D+  WL  L  +       P   +     S   
Sbjct: 508 EIEGNDCTFEITGNTVERIVVHCNNNQDFQEWLEQLNRLIR----GPASCSSLSKTSSSS 563

Query: 349 GSGRGSLSSGGQ-----------TSWDSGCLAP-PSTRTSHSLPESSVPSTVGCSSQHTP 396
            S   S SS GQ             W   CL P P  R S +L      S +   S  +P
Sbjct: 564 CSAHSSFSSTGQPRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKERMSYILKESSKSP 623

Query: 397 ------LHRLSLESSPDAPDHTSETSHSPLYAD 423
                 LH+   E  P   ++    S + L  D
Sbjct: 624 KTMKKFLHKRKTERKPSEEEYVIRKSTAALEED 656



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 35/136 (25%), Positives = 62/136 (45%), Gaps = 7/136 (5%)

Query: 69  QRENLEQPFLSVFKKGRRRVPVRNLGKVVHYAKVQLRFQHSQDVSDCYLELFPAHLYFQA 128
           +R+ LE   LS   +      ++NLG V+  ++V +++   ++  + YL LF   L   +
Sbjct: 423 KRKQLELQILSEPIQAWEGEDIKNLGNVIFMSQVMVQYGACEEKEERYLMLFSNVLIMLS 482

Query: 129 HGSE--GLTFQGLLPLTELSVCPLEG--SREHAFQITGPLPAPLLVLCPSRAELDRWLYH 184
                 G  +QG +P+    V  L+     +  F+ITG     ++V C +  +   WL  
Sbjct: 483 ASPRMSGFIYQGKIPIAGTVVTRLDEIEGNDCTFEITGNTVERIVVHCNNNQDFQEWLEQ 542

Query: 185 LEKQTALLGGPRRCHS 200
           L +   L+ GP  C S
Sbjct: 543 LNR---LIRGPASCSS 555


>gi|169168458 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 353

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 52/180 (28%), Positives = 69/180 (38%), Gaps = 27/180 (15%)

Query: 417 HSPLYADP---YTPPATSHRRVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPR 473
           H P    P   Y P    + R    RG     S   S R P   +PL S+P SVP +   
Sbjct: 127 HLPRQVRPGPVYKPAPARNHRPRGGRGKASPTSFHVSPRAPP--APLASMPSSVPKTSIE 184

Query: 474 SCSSGPAGPYLLSKKGALQSRAAQR---HRGSAKDGGPQPPDAPQ----LVSSAREGSPE 526
           S  S    P  LS   A +     +   HR  A    P P  + +    L S +    PE
Sbjct: 185 SLGS----PSSLSSSQASEPLCPLKHPSHRPPASTLSPNPTSSTESLGYLSSLSSSQPPE 240

Query: 527 PWLPL------TDGRSPRRSRDPGYDHLWDETLSSSHQK----CPQLGGPEASGGLVQWI 576
           P  PL        GRSP R R+PG+   W +++ +  +     CP    PE S     W+
Sbjct: 241 PLRPLKHPSHKPHGRSPPRRRNPGWVS-WSDSMQADSETDAIICPMCKAPERSCPHTWWV 299


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 65/236 (27%), Positives = 83/236 (35%), Gaps = 45/236 (19%)

Query: 330 REGAPPLPGAESFPGSQVMGSGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSVPSTVG 389
           R+  P LP   +  GS+  G+G          SW  G L+P  +R     PE ++  + G
Sbjct: 527 RKQQPQLPRPPTTGGSE--GAGAAPCPPNPANSWVPG-LSPGGSRRPPRSPERTLSPSSG 583

Query: 390 CSSQH-TPLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSAM 448
            SSQ  TP       + P A         SP  A P  P   +  R           S  
Sbjct: 584 YSSQSGTPTLPPKGLAGPPA---------SPGKAQPPKPERVTSLRSPGASVSSSLTSLC 634

Query: 449 QSARGPTPSS-----------------PLPSVPV--SVPASDPRSCSSGPAGPYLLSKKG 489
            S+  P PS                  P P VP   S P S PRS    PA P       
Sbjct: 635 SSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRS--PNPAAP------- 685

Query: 490 ALQSRAAQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRSRDPGY 545
           AL + A      S  D  PQ P  PQ   +  + SP     ++  +SP  S  P Y
Sbjct: 686 ALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESP----VISKDQSPPPSPPPSY 737


>gi|239508790 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 490

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 71/218 (32%), Positives = 83/218 (38%), Gaps = 34/218 (15%)

Query: 332 GAPPLPGAESFPGSQVMG--SGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSVPST-- 387
           G P LP   S P S V    S   SL SG   S  S   +PPS   S   P S VPS   
Sbjct: 127 GVPSLPSDVSSPPSDVPSLLSDVPSLLSG-VPSPPSDVPSPPSDVPS---PPSDVPSLLS 182

Query: 388 -VGCSSQHTPLHRLSLESSP-DAP---DHTSETSHSPLYADPYTPPATSHRRVTDVRGLE 442
            V       P     + S P D P   D  S  S  PL +D  +PP+      +DV  L 
Sbjct: 183 GVPSPPSDVPSPPSDVPSPPSDVPLLSDVPSPPSDVPLLSDVPSPPSDVPSLPSDVPSLS 242

Query: 443 EFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGS 502
                      P+P S +PS+   VP S P   S     P LLS   +L S        S
Sbjct: 243 GV---------PSPPSDVPSLLSGVP-SPPSDISPPSDVPSLLSDVPSLPSDVP-----S 287

Query: 503 AKDGGPQPP-DAPQLVSSARE-----GSPEPWLPLTDG 534
              G P PP D P L+S          SP   +PL  G
Sbjct: 288 LLSGVPSPPSDVPSLLSDVPSPPSDVPSPPSDIPLLSG 325



 Score = 32.7 bits (73), Expect = 0.93
 Identities = 45/150 (30%), Positives = 64/150 (42%), Gaps = 18/150 (12%)

Query: 392 SQHTPLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSAMQSA 451
           S H PL  +S   S  +P ++  + H PL + P+    + HR +     +   LS +   
Sbjct: 66  SPHHPL--MSPHYSLVSPQYSPVSPHCPLVS-PHYSLVSPHRPL-----VSPLLSGV--- 114

Query: 452 RGPTPSSPLPSVPVSVPASDPRSCSSGPAG-PYLLSKKGALQSRAAQRHRG--SAKDGGP 508
             P+P S +PS+   VP S P   SS P+  P LLS   +L S          S     P
Sbjct: 115 --PSPPSDVPSLLSGVP-SLPSDVSSPPSDVPSLLSDVPSLLSGVPSPPSDVPSPPSDVP 171

Query: 509 QPP-DAPQLVSSAREGSPEPWLPLTDGRSP 537
            PP D P L+S       +   P +D  SP
Sbjct: 172 SPPSDVPSLLSGVPSPPSDVPSPPSDVPSP 201


>gi|28559039 mediator complex subunit 1 [Homo sapiens]
          Length = 1581

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 51/187 (27%), Positives = 74/187 (39%), Gaps = 8/187 (4%)

Query: 338  GAESFPGSQVMGSGRGSL-SSGGQTSWDSGCLAPPSTRTSHSLPESSVPSTVGCSSQHTP 396
            G+ S   S  M S +GS  SS  + S  SG     S  T H L   S  + +    + + 
Sbjct: 1121 GSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSS 1180

Query: 397  LHRLSLESSPDAPDHT-----SETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSAMQSA 451
            L   SL     +P H+     S+   SP+   P TPP++  +           +S   S+
Sbjct: 1181 LMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSS 1240

Query: 452  RGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKDGGPQPP 511
             G   SS L S   S+    P S +S  A     S  G+  S +  +H GS+K   P   
Sbjct: 1241 SGMKSSSGLGS-SGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQH-GSSKGKSPSRN 1298

Query: 512  DAPQLVS 518
              P L +
Sbjct: 1299 KKPSLTA 1305


>gi|157311635 FAM83H [Homo sapiens]
          Length = 1179

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 68/239 (28%), Positives = 99/239 (41%), Gaps = 49/239 (20%)

Query: 329  HREGAPPLPGAESFPGSQVMGSGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSVPSTV 388
            H+E A   PGA S   +Q++ +    L   G     S  L+  S  TS    +S +P  +
Sbjct: 802  HQE-AERQPGAASLTAAQLLDT----LGRSGSDRLPSRFLSAQSHSTSPQGLDSPLP--L 854

Query: 389  GCSSQHTPLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSAM 448
              S  H  LH  S  S   A     E   SP        P  S RR +   G  E   + 
Sbjct: 855  EGSGAHQVLHNESKGSPTSA---YPERKGSPT-------PGFSTRRGSPTTGFIEQKGSP 904

Query: 449  QSA----RG----PTP---SSPLPSVP-------VSVPASDPRS--CSSGPAGPYLLSKK 488
             SA    RG    P P   SSP+P VP       +++    P++     GP+GP  + +K
Sbjct: 905  TSAYPERRGSPVPPVPERRSSPVPPVPERRGSLTLTISGESPKAGPAEEGPSGPMEVLRK 964

Query: 489  GALQSRAAQRHRGSAK---DGG-PQP-----PDAPQLVSSAREGSPEPWLPLTDGRSPR 538
            G+L+ R     +G  +   +GG P P     P++P+ +S  +  S E     T+ R PR
Sbjct: 965  GSLRLRQLLSPKGERRMEDEGGFPVPQENGQPESPRRLSLGQGDSTE---AATEERGPR 1020


>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
          Length = 863

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 50/224 (22%), Positives = 82/224 (36%), Gaps = 31/224 (13%)

Query: 331 EGAPPLPGAESFPGS--QVMGSGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSVPSTV 388
           E  P +P     PG   ++     G  +   + + +S   APP+ R   SL + ++    
Sbjct: 275 EARPQIPTKPRVPGKLQELASPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQENLVEQA 334

Query: 389 GCSSQ-HTPLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSA 447
           G SS  +  LH L +      P   SE + +P    P+                   ++ 
Sbjct: 335 GSSSLVNGRLHELPVPKPRGTPK-PSEGTPAPRKDPPW-------------------ITL 374

Query: 448 MQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLL-SKKGALQSRAAQRHRGSAKDG 506
           +Q+     P+   PS     P+ D R   +G        S   +L+S+         +D 
Sbjct: 375 VQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEVAQPSPTASLESKPYNPFEEEEEDK 434

Query: 507 GPQPPDAPQLVSSAREGSPE-------PWLPLTDGRSPRRSRDP 543
             + P AP L +S   G PE       PW  +T   SP+  + P
Sbjct: 435 EEEAPAAPSLATSPALGHPESTPKSLHPWYGITPTSSPKTKKRP 478


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 37/177 (20%), Positives = 63/177 (35%), Gaps = 8/177 (4%)

Query: 369 APPSTRTSHSLPESSVPSTVGCSSQHTPLHRLSLESSPDAPDHTSETSHSPLYADPYTPP 428
           AP +T+++ + P+   P+T    +  TP       +   AP  T     +P    P TP 
Sbjct: 248 APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP- 306

Query: 429 ATSHRRVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKK 488
               ++       E   +  +     TP  P P+     P +      + P  P   + K
Sbjct: 307 ----KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK 362

Query: 489 GALQSRAAQRHRGSAKDGGPQPP--DAPQLVSSAREGSPEPWLPLTDGRSPRRSRDP 543
               +   +    + K+  P  P   AP    SA   + EP  P T   +P   ++P
Sbjct: 363 EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP-APTTTKSAPTTPKEP 418


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 37/177 (20%), Positives = 63/177 (35%), Gaps = 8/177 (4%)

Query: 369 APPSTRTSHSLPESSVPSTVGCSSQHTPLHRLSLESSPDAPDHTSETSHSPLYADPYTPP 428
           AP +T+++ + P+   P+T    +  TP       +   AP  T     +P    P TP 
Sbjct: 289 APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP- 347

Query: 429 ATSHRRVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKK 488
               ++       E   +  +     TP  P P+     P +      + P  P   + K
Sbjct: 348 ----KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK 403

Query: 489 GALQSRAAQRHRGSAKDGGPQPP--DAPQLVSSAREGSPEPWLPLTDGRSPRRSRDP 543
               +   +    + K+  P  P   AP    SA   + EP  P T   +P   ++P
Sbjct: 404 EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP-APTTTKSAPTTPKEP 459


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 37/177 (20%), Positives = 63/177 (35%), Gaps = 8/177 (4%)

Query: 369 APPSTRTSHSLPESSVPSTVGCSSQHTPLHRLSLESSPDAPDHTSETSHSPLYADPYTPP 428
           AP +T+++ + P+   P+T    +  TP       +   AP  T     +P    P TP 
Sbjct: 341 APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP- 399

Query: 429 ATSHRRVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKK 488
               ++       E   +  +     TP  P P+     P +      + P  P   + K
Sbjct: 400 ----KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK 455

Query: 489 GALQSRAAQRHRGSAKDGGPQPP--DAPQLVSSAREGSPEPWLPLTDGRSPRRSRDP 543
               +   +    + K+  P  P   AP    SA   + EP  P T   +P   ++P
Sbjct: 456 EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP-APTTTKSAPTTPKEP 511


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 37/177 (20%), Positives = 63/177 (35%), Gaps = 8/177 (4%)

Query: 369 APPSTRTSHSLPESSVPSTVGCSSQHTPLHRLSLESSPDAPDHTSETSHSPLYADPYTPP 428
           AP +T+++ + P+   P+T    +  TP       +   AP  T     +P    P TP 
Sbjct: 382 APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP- 440

Query: 429 ATSHRRVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKK 488
               ++       E   +  +     TP  P P+     P +      + P  P   + K
Sbjct: 441 ----KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK 496

Query: 489 GALQSRAAQRHRGSAKDGGPQPP--DAPQLVSSAREGSPEPWLPLTDGRSPRRSRDP 543
               +   +    + K+  P  P   AP    SA   + EP  P T   +P   ++P
Sbjct: 497 EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP-APTTTKSAPTTPKEP 552


>gi|221139926 NHS-like 1 [Homo sapiens]
          Length = 1606

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 53/217 (24%), Positives = 75/217 (34%), Gaps = 42/217 (19%)

Query: 334  PPLPGAESFPGSQV----MGSGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSVPSTVG 389
            P LP +E  P   +    M   R   ++ GQ     G L PPST+   S P   + +T  
Sbjct: 1013 PLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSLRPPSTKEETSRPPMPLITTEA 1072

Query: 390  CSS-QHTPLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSAM 448
                Q  P+ + S   +    + T++   +P+    +  P                 SA 
Sbjct: 1073 LQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKP-----------------SAF 1115

Query: 449  QSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKDGGP 508
              +R  T      S P SV +S P    S   G                 H  +A+ GGP
Sbjct: 1116 LKSRNSTNEMESESQPASVTSSLPTPAKSSSQGD----------------HGSAAERGGP 1159

Query: 509  --QPPDAPQLVSSAREGSPEPWLPLTDGRSPRRSRDP 543
              + P AP    +    SP    PL D  SP R   P
Sbjct: 1160 VSRSPGAPSAGEAEARPSPST-TPLPDS-SPSRKPPP 1194



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 51/203 (25%), Positives = 74/203 (36%), Gaps = 23/203 (11%)

Query: 334  PPLPGAESFPGSQVMGSGRGSLSSGGQTSWDSGCLAP--PSTRTSHSLPESSVPST-VGC 390
            P +P  +S   S V  S   +  S   ++  SG +    P+  +  + P   VPS    C
Sbjct: 883  PKVPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPC 942

Query: 391  SSQHTPLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSAMQS 450
             +  +P         P  P  T  +  SPL   P  PP      +      +  LS  + 
Sbjct: 943  PADRSPF-------LPPPPPVTDCSQGSPLPHSPVFPPPPPEALIPFCSPPDWCLSPPRP 995

Query: 451  ARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKD--GGP 508
            A  P     LP  PVS+P   P   SS P     L  K    +R    + G  +   G  
Sbjct: 996  ALSPI----LPDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSL 1051

Query: 509  QPPDAPQLVSSAREGSPEPWLPL 531
            +PP       S +E +  P +PL
Sbjct: 1052 RPP-------STKEETSRPPMPL 1067


>gi|41281612 zinc finger protein 828 [Homo sapiens]
          Length = 812

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 55/214 (25%), Positives = 78/214 (36%), Gaps = 35/214 (16%)

Query: 333 APPLPGAESFPGSQVMGSGRGSLSSGGQTSWDSGCLAPPSTRTSHSLP-ESSVPSTVGCS 391
           +PPLP  +  P +        +LS   +T      L+P S + +   P E   P +V   
Sbjct: 108 SPPLPEHQKIPCNSAEPKSIPALSM--ETQKLGSVLSPESPKPTPLTPLEPQKPGSVVSP 165

Query: 392 SQHTPLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSAMQSA 451
              TPL       SP+     S +S  P    P + P    +++  V   E    A  S 
Sbjct: 166 ELQTPL------PSPEPSKPASVSSPEP----PKSVPVCESQKLAPVPSPEPQKPAPVSP 215

Query: 452 RG--PTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKDGGPQ 509
                T S+P P      P +     +S P  P L +               S +  GP 
Sbjct: 216 ESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAA---------------SPEPWGPS 260

Query: 510 PPDAPQLVSSAREGSPEPWLPLTDGRSPRRSRDP 543
           P  +P+   SAR  SPEP  P     SP  S +P
Sbjct: 261 PAASPESRKSARTTSPEPRKP-----SPSESPEP 289


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 43/131 (32%), Positives = 59/131 (45%), Gaps = 16/131 (12%)

Query: 375  TSHSLPESSVPSTVGCSSQHT--PLHRLSLES----SPDAPDHTSETSHSPLYADPYTPP 428
            +SHS P++S PS VG SS     P+H  +L S    S      T+  S SPL+  P +P 
Sbjct: 2147 SSHSSPQTSSPS-VGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLF--PSSPA 2203

Query: 429  ATSHRRVT------DVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGP 482
            A++  R T          L   L        PTPSS L S  ++ P S PR+ +S    P
Sbjct: 2204 ASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFP-STPRTTASTHTAP 2262

Query: 483  YLLSKKGALQS 493
               S+    +S
Sbjct: 2263 AFSSQSTTSRS 2273



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 53/208 (25%), Positives = 76/208 (36%), Gaps = 26/208 (12%)

Query: 335  PLPGAESFPGSQVMGSGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSVPSTVGCSSQH 394
            P P +   P   V  SG     S   T+  S  L   ++ T H  PE +  ST   +  H
Sbjct: 1716 PNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHH--PEVTSTSTTSITPNH 1773

Query: 395  T------PLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSAM 448
            T      P+   +  +S   P  T  T+HSP      T P +S   VT         S  
Sbjct: 1774 TSTGTRTPVAHTTSATSSRLP--TPFTTHSPPTG---TTPISSTGPVTAT-------SFQ 1821

Query: 449  QSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKDGGP 508
             +   PTPS P  ++P  VP+      +  P+   ++       + +A  H  S   G  
Sbjct: 1822 TTTTYPTPSHPHTTLPTHVPSFSTSLVT--PSTHTVIIPTHTQMATSASIH--SMPTGTI 1877

Query: 509  QPPDAPQLVSSAREGSPEPWLPLTDGRS 536
             PP   +   S    +  P  P T G S
Sbjct: 1878 PPPTTIKATGSTH--TAPPMTPTTSGTS 1903



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 36/116 (31%), Positives = 52/116 (44%), Gaps = 18/116 (15%)

Query: 362  SWDSGCLAPPST----RTSHSLPESSVPSTVGCSSQHTPLHRLSLESSPDAPDHTSETSH 417
            S  +G + PP+T     ++H+ P  + P+T G S   +P    + ++S   P HTS T H
Sbjct: 1871 SMPTGTIPPPTTIKATGSTHTAPPMT-PTTSGTSQ--SPSSFSTAKTSTSLPYHTSSTHH 1927

Query: 418  ---SPLYADPYTPPATSHRRVTDVRGLEEFLSAMQSARGPTP----SSPLPSVPVS 466
               +P      TP  TS    T  R      ++  S+R PTP    S P  S P S
Sbjct: 1928 PEVTPTSTTNITPKHTS----TGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFS 1979



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 35/119 (29%), Positives = 49/119 (41%), Gaps = 12/119 (10%)

Query: 356  SSGGQTSWDSGCLAPP----STRTSHSLPESSVPSTVGCSSQHTPLHRLSLESSPDA-PD 410
            +S    S  +G + PP    +T ++H+ P  + P+T G S  H+     S   +P +   
Sbjct: 1472 TSASNHSAPTGTIPPPTTLKATGSTHTAPPIT-PTTSGTSQAHS---SFSTNKTPTSLHS 1527

Query: 411  HTSETSH---SPLYADPYTPPATSHRRVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVS 466
            HTS T H   +P      TP  TS R  T V       S+       T S P  S P S
Sbjct: 1528 HTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFS 1586


>gi|23510413 sorting nexin 26 [Homo sapiens]
          Length = 1126

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 52/182 (28%), Positives = 69/182 (37%), Gaps = 42/182 (23%)

Query: 348  MGSGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSVPSTVGCSSQHTPLHR-----LSL 402
            +G+  GS  SG   SW              S+P   + ++ G   Q  PLHR     LS 
Sbjct: 928  IGASEGSPYSGPTRSWSP----------FRSMPPDRLNASYGMLGQSPPLHRSPDFLLSY 977

Query: 403  ESSPDA--PDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSAMQSARGPTPSSPL 460
              +P    PDH             Y+ P    RR T    L  +++     RGP+P+S  
Sbjct: 978  PPAPSCFPPDHLG-----------YSAPQHPARRPTPPEPL--YVNLALGPRGPSPASSS 1024

Query: 461  PSVPVSVPAS--DPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKDGGPQPPDAPQLVS 518
             S P + P S  DP     GP  P L  K+     RA    R   +  GP  P  P L+ 
Sbjct: 1025 SSSPPAHPRSRSDP-----GPPVPRLPQKQ-----RAPWGPRTPHRVPGPWGPPEPLLLY 1074

Query: 519  SA 520
             A
Sbjct: 1075 RA 1076



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 56/218 (25%), Positives = 74/218 (33%), Gaps = 14/218 (6%)

Query: 337 PGAESFPGSQVMGSGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPES----SVPSTVGCSS 392
           PG  S+     +G G  S+       W  G  APP  + S S P++    S  S    SS
Sbjct: 586 PGGSSWKTFFALGRGP-SVPRKKPLPWLGGTRAPP--QPSGSRPDTVTLRSAKSEESLSS 642

Query: 393 QHTPLHRLSLESSPDAPDHTSETSHSPLYADPYTPPAT--SHRRVTDVRGLE--EFLSAM 448
           Q +    L    +P +   T   S          P     +   +TD    E    L   
Sbjct: 643 QASGAELLGAGGAPASATPTPALSPGRSLRPHLIPLLLRGAEAPLTDACQQEMCSKLRGA 702

Query: 449 QSARGPTPSSPLPSVPVSV--PASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKDG 506
           Q   GP   SPLP  P+S+  P   P      PA    L+     Q  A Q+ +     G
Sbjct: 703 QGPLGPDMESPLPPPPLSLLRPGGAPPPPPKNPARLMALALAERAQQVAEQQSQQEC-GG 761

Query: 507 GPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRSRDPG 544
            P    +P   S + E   EP      G  P     PG
Sbjct: 762 TPPASQSPFHRSLSLEVGGEPLGTSGSGPPPNSLAHPG 799


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 62/212 (29%), Positives = 72/212 (33%), Gaps = 47/212 (22%)

Query: 325 RAVTHREGAPPLPGAESFPGSQVMGSGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSV 384
           R   HRE  PP P   + P   V  + R S SS            PP    S   P    
Sbjct: 274 RPSIHREAVPPPPPQNNKP--PVPSTPRPSASSQAP---------PPPPPPSRPGPPPLP 322

Query: 385 PSTVGCS-SQHTPLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEE 443
           PS+ G   +   P   LSL SS   P   S     PL      PP  S R    VR    
Sbjct: 323 PSSSGNDETPRLPQRNLSLSSS--TPPLPSPGRSGPL------PPPPSERPPPPVRD--- 371

Query: 444 FLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSG-PAGPYLLSKKGALQSRAAQRHRGS 502
                     P  S PLP  P   P S   S S   PA P L S+ G    R+       
Sbjct: 372 ---------PPGRSGPLPPPP---PVSRNGSTSRALPATPQLPSRSGVDSPRS------- 412

Query: 503 AKDGGPQPPDAPQLVSSAREGSPEPWLPLTDG 534
               GP+PP  P   S+     P P   + +G
Sbjct: 413 ----GPRPPLPPDRPSAGAPPPPPPSTSIRNG 440



 Score = 33.1 bits (74), Expect = 0.71
 Identities = 54/231 (23%), Positives = 75/231 (32%), Gaps = 63/231 (27%)

Query: 324 LRAVTHREGAPPLPGAES----------FPGSQVMGSGRGSLSSGGQTSWDSGCLAPPST 373
           +++  H  G+PP+PG             FPG++    G GS+     +S       PP  
Sbjct: 194 IQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPP-- 251

Query: 374 RTSHSLPESSVPSTVGCSSQHTPLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHR 433
                LP              TP   L  +  P  P   +  S   ++ +   PP     
Sbjct: 252 -----LPP-------------TPSRALDDKPPPPPPPVGNRPS---IHREAVPPPPP--- 287

Query: 434 RVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQS 493
                          Q+ + P PS+P PS     P   P     GP  P   S  G  ++
Sbjct: 288 ---------------QNNKPPVPSTPRPSASSQAPPPPPPPSRPGPP-PLPPSSSGNDET 331

Query: 494 -RAAQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRSRDP 543
            R  QR+   +          P L S  R G   P  P    R P   RDP
Sbjct: 332 PRLPQRNLSLSS-------STPPLPSPGRSG---PLPPPPSERPPPPVRDP 372


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 62/212 (29%), Positives = 72/212 (33%), Gaps = 47/212 (22%)

Query: 325 RAVTHREGAPPLPGAESFPGSQVMGSGRGSLSSGGQTSWDSGCLAPPSTRTSHSLPESSV 384
           R   HRE  PP P   + P   V  + R S SS            PP    S   P    
Sbjct: 274 RPSIHREAVPPPPPQNNKP--PVPSTPRPSASSQAP---------PPPPPPSRPGPPPLP 322

Query: 385 PSTVGCS-SQHTPLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEE 443
           PS+ G   +   P   LSL SS   P   S     PL      PP  S R    VR    
Sbjct: 323 PSSSGNDETPRLPQRNLSLSSS--TPPLPSPGRSGPL------PPPPSERPPPPVRD--- 371

Query: 444 FLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSG-PAGPYLLSKKGALQSRAAQRHRGS 502
                     P  S PLP  P   P S   S S   PA P L S+ G    R+       
Sbjct: 372 ---------PPGRSGPLPPPP---PVSRNGSTSRALPATPQLPSRSGVDSPRS------- 412

Query: 503 AKDGGPQPPDAPQLVSSAREGSPEPWLPLTDG 534
               GP+PP  P   S+     P P   + +G
Sbjct: 413 ----GPRPPLPPDRPSAGAPPPPPPSTSIRNG 440



 Score = 33.1 bits (74), Expect = 0.71
 Identities = 54/231 (23%), Positives = 75/231 (32%), Gaps = 63/231 (27%)

Query: 324 LRAVTHREGAPPLPGAES----------FPGSQVMGSGRGSLSSGGQTSWDSGCLAPPST 373
           +++  H  G+PP+PG             FPG++    G GS+     +S       PP  
Sbjct: 194 IQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPP-- 251

Query: 374 RTSHSLPESSVPSTVGCSSQHTPLHRLSLESSPDAPDHTSETSHSPLYADPYTPPATSHR 433
                LP              TP   L  +  P  P   +  S   ++ +   PP     
Sbjct: 252 -----LPP-------------TPSRALDDKPPPPPPPVGNRPS---IHREAVPPPPP--- 287

Query: 434 RVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQS 493
                          Q+ + P PS+P PS     P   P     GP  P   S  G  ++
Sbjct: 288 ---------------QNNKPPVPSTPRPSASSQAPPPPPPPSRPGPP-PLPPSSSGNDET 331

Query: 494 -RAAQRHRGSAKDGGPQPPDAPQLVSSAREGSPEPWLPLTDGRSPRRSRDP 543
            R  QR+   +          P L S  R G   P  P    R P   RDP
Sbjct: 332 PRLPQRNLSLSS-------STPPLPSPGRSG---PLPPPPSERPPPPVRDP 372


>gi|187937179 apoptosis-associated tyrosine kinase [Homo sapiens]
          Length = 1374

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 68/243 (27%), Positives = 97/243 (39%), Gaps = 41/243 (16%)

Query: 318 GHWLLCLRAVTHRE-----GAPPLPGAESFPGSQ--VMGSGRGSLSSGGQTSWDSGCLAP 370
           G  LL L+A + +E     G P L  A+    +   V  S   + SSGG        LA 
Sbjct: 725 GEPLLGLQAASAQEPGCCPGLPHLCSAQGLAPAPCLVTPSWTETASSGGDHPQAEPKLAT 784

Query: 371 PSTRTSHS-LPESSVPSTVGCSSQHTPLHRLSLESSPDAPDHTSETSHSPLYADPYTPPA 429
            +  T+   LP  SVPS    S +  PL      S+PDAPD           A P +P  
Sbjct: 785 EAEGTTGPRLPLPSVPSP---SQEGAPLPSEEA-SAPDAPD-----------ALPDSPTP 829

Query: 430 TSHRRVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKG 489
            +   V+ ++        + SA   + SSP     V  P+S+    +   +G +  +   
Sbjct: 830 ATGGEVSAIK--------LASALNGSSSSP----EVEAPSSEDEDTAEATSGIFTDTSSD 877

Query: 490 ALQSR---AAQRHRGSAKD-GGPQPPDAPQLVSSAREGSPEPWLPLTDGRS--PRRSRDP 543
            LQ+R        R   K  G P   D+  + SSA +G  E + P   G S    R+ D 
Sbjct: 878 GLQARRPDVVPAFRSLQKQVGTPDSLDSLDIPSSASDGGYEVFSPSATGPSGGQPRALDS 937

Query: 544 GYD 546
           GYD
Sbjct: 938 GYD 940



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 27/90 (30%), Positives = 38/90 (42%), Gaps = 7/90 (7%)

Query: 456 PSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRA--AQRHRGSAKDGGPQPPDA 513
           P  PL  +  +  A +P  C   P  P+L S +G   +          +A  GG  P   
Sbjct: 724 PGEPLLGLQAA-SAQEPGCC---PGLPHLCSAQGLAPAPCLVTPSWTETASSGGDHPQAE 779

Query: 514 PQLVSSAREGSPEPWLPLTDGRSPRRSRDP 543
           P+L + A EG+  P LPL    SP +   P
Sbjct: 780 PKLATEA-EGTTGPRLPLPSVPSPSQEGAP 808


>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
          Length = 2089

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 64/233 (27%), Positives = 84/233 (36%), Gaps = 33/233 (14%)

Query: 332  GAPPLPGAESFP---GSQVMGSGRGS-LSSGGQTSWDSGCLAPPSTRTSHSLPESSVP-- 385
            GA  LPG  S P   GSQ    GRGS +S          C  PP+ + S       V   
Sbjct: 972  GAGDLPGPTSAPVPSGSQ--SGGRGSPVSPRRHQKGLLNCKMPPAEKASRIRAAEKVSRG 1029

Query: 386  ---STVGCSSQHTPLHRLSLESSPDAPDHTSETSH--SPLYADPYTPPATSHRRVTDVRG 440
               S   C     P       + P  P ++    H   P    P  P      R T   G
Sbjct: 1030 DQESPDACLPPTVP----EAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDG 1085

Query: 441  LEEFLSAMQSAR----GPTP------SSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGA 490
             +E   A  S+      P P      SS +   P +  A +P   S+  A P  ++ K  
Sbjct: 1086 SQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHP-STSTAQP--VTPKPT 1142

Query: 491  LQSRAAQRHRGSAKDGGPQPPDAPQLVSSAREGSP---EPWLPLTDGRSPRRS 540
             Q+  ++ +R S K   P  P AP+L  S     P   EP   +T GR  R S
Sbjct: 1143 SQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSS 1195



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 50/197 (25%), Positives = 74/197 (37%), Gaps = 26/197 (13%)

Query: 361  TSWDSGCLAPPSTRTSHSLPESSVPSTVGCSSQHTPLHRLSLESS-PDAPDHTSETSHSP 419
            TS D      P++RT+ S    S   T        P  ++S  +  P  P  TS T+ S 
Sbjct: 1295 TSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSR 1354

Query: 420  LYAD------------PYTPPATSHRR-VTDVRGLEEFLSAMQSARGPTPSSPLPSVPVS 466
                            P  PP+TS  + VT              + G TP + +P+ P  
Sbjct: 1355 TNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAP-- 1412

Query: 467  VPASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKDGGPQPPDAPQL---VSSAREG 523
                +P + +  P  P   S     Q+   + +R S K      P AP+L    S+ +  
Sbjct: 1413 --KLEPSTSTDQPVTPEPTS-----QATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPV 1465

Query: 524  SPEPWLPLTDGRSPRRS 540
            +PEP    T GR+ R S
Sbjct: 1466 TPEPTSQATRGRTDRSS 1482



 Score = 33.9 bits (76), Expect = 0.42
 Identities = 49/196 (25%), Positives = 79/196 (40%), Gaps = 31/196 (15%)

Query: 351  GRGSLSSGG--QTSWDSGCLAPPSTRTSHSL-PESSVPSTVGCSSQHTPLHRLSLESSPD 407
            GR + SSG   +T   +     PST T   + PE +  +T G +++ +   +      P 
Sbjct: 1394 GRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSV--KTPETVVPT 1451

Query: 408  APDHTSETSHSPLYADPYTPPATSHRRVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSV 467
            AP+    TS       P TP  TS                 Q+ RG T  S + +    V
Sbjct: 1452 APELQPSTSTD----QPVTPEPTS-----------------QATRGRTDRSSVKTPETVV 1490

Query: 468  PASDPRSCSSGPAGPYLLSKKGALQSRAAQRHRGSAKDGGPQPPDAPQL---VSSAREGS 524
            P +     S+    P  ++ +   ++   +++R S K      P AP+L    S+ +  +
Sbjct: 1491 PTAPELQASASTDQP--VTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVT 1548

Query: 525  PEPWLPLTDGRSPRRS 540
            PEP    T GR+ R S
Sbjct: 1549 PEPTSRATRGRTNRSS 1564


>gi|209862845 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 4 isoform 1 [Homo sapiens]
          Length = 964

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 31/78 (39%), Positives = 36/78 (46%), Gaps = 4/78 (5%)

Query: 452 RGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRA-AQRHRGSAKDGGPQP 510
           RGP  S  L S P   PAS PR  S  P G    S  G   S + A   RGS  + G +P
Sbjct: 304 RGPEDSWLLLSAPGPTPAS-PRPAS--PCGKRRYSSSGTPSSASPALSRRGSLGEEGSEP 360

Query: 511 PDAPQLVSSAREGSPEPW 528
           P  P L  +   GSP P+
Sbjct: 361 PPPPPLPLARDPGSPGPF 378


>gi|27886563 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 4 isoform 2 [Homo sapiens]
          Length = 902

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 31/78 (39%), Positives = 36/78 (46%), Gaps = 4/78 (5%)

Query: 452 RGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLSKKGALQSRA-AQRHRGSAKDGGPQP 510
           RGP  S  L S P   PAS PR  S  P G    S  G   S + A   RGS  + G +P
Sbjct: 241 RGPEDSWLLLSAPGPTPAS-PRPAS--PCGKRRYSSSGTPSSASPALSRRGSLGEEGSEP 297

Query: 511 PDAPQLVSSAREGSPEPW 528
           P  P L  +   GSP P+
Sbjct: 298 PPPPPLPLARDPGSPGPF 315


>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a2 isoform a [Homo sapiens]
          Length = 1590

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 51/189 (26%), Positives = 67/189 (35%), Gaps = 37/189 (19%)

Query: 332 GAPPLPGAESFPGSQ---VMGSGRGSLSSGGQTSWDSG-CLAPPSTRTSHSLPE--SSVP 385
           GA P PG    PG     ++G   G   S G      G    PPS   SH +P   S+  
Sbjct: 8   GAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSV--SHPMPTMGSTDF 65

Query: 386 STVGCSSQHTPL------------HRLSLESSPDAPDH-------TSETSHSPLYADPYT 426
              G    H P+            H  S++ +   P H       +    HS  Y  P+ 
Sbjct: 66  PQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPPHPGMGPPQSPMDQHSQGYMSPHP 125

Query: 427 PPATSHRRVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLS 486
            P           G  E +S+  S  GPTP    PS P ++   DP++ S    GP   S
Sbjct: 126 SPL----------GAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNRGPSPFS 175

Query: 487 KKGALQSRA 495
                Q RA
Sbjct: 176 PVQLHQLRA 184


>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a2 isoform b [Homo sapiens]
          Length = 1572

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 51/189 (26%), Positives = 67/189 (35%), Gaps = 37/189 (19%)

Query: 332 GAPPLPGAESFPGSQ---VMGSGRGSLSSGGQTSWDSG-CLAPPSTRTSHSLPE--SSVP 385
           GA P PG    PG     ++G   G   S G      G    PPS   SH +P   S+  
Sbjct: 8   GAMPHPGPSPGPGPSPGPILGPSPGPGPSPGSVHSMMGPSPGPPSV--SHPMPTMGSTDF 65

Query: 386 STVGCSSQHTPL------------HRLSLESSPDAPDH-------TSETSHSPLYADPYT 426
              G    H P+            H  S++ +   P H       +    HS  Y  P+ 
Sbjct: 66  PQEGMHQMHKPIDGIHDKGIVEDIHCGSMKGTGMRPPHPGMGPPQSPMDQHSQGYMSPHP 125

Query: 427 PPATSHRRVTDVRGLEEFLSAMQSARGPTPSSPLPSVPVSVPASDPRSCSSGPAGPYLLS 486
            P           G  E +S+  S  GPTP    PS P ++   DP++ S    GP   S
Sbjct: 126 SPL----------GAPEHVSSPMSGGGPTPPQMPPSQPGALIPGDPQAMSQPNRGPSPFS 175

Query: 487 KKGALQSRA 495
                Q RA
Sbjct: 176 PVQLHQLRA 184


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,502,427
Number of Sequences: 37866
Number of extensions: 1626804
Number of successful extensions: 9170
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 469
Number of HSP's that attempted gapping in prelim test: 8260
Number of HSP's gapped (non-prelim): 1349
length of query: 576
length of database: 18,247,518
effective HSP length: 108
effective length of query: 468
effective length of database: 14,157,990
effective search space: 6625939320
effective search space used: 6625939320
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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