Guide to the Human Genome
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Name: ARHGEF6 Sequence: fasta or formatted (776aa) NCBI GI: 22027525
Description:

Rac/Cdc42 guanine nucleotide exchange factor 6

Referenced in:

Rho and Rac

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.3         33           2
 C cysteine            2.8         22           1
 D aspartate           3.4         26           2
 E glutamate           9.8         76           3
 F phenylalanine       3.1         24           1
 G glycine             4.9         38           2
 H histidine           1.5         12           1
 I isoleucine          5.2         40           2
 K lysine              7.1         55           2
 L leucine            11.1         86           2
 M methionine          2.3         18           1
 N asparagine          4.9         38           3
 P proline             4.8         37           2
 Q glutamine           5.5         43           2
 R arginine            4.6         36           2
 S serine              9.7         75           4
 T threonine           6.1         47           2
 V valine              5.8         45           2
 W tryptophan          0.9          7           2
 Y tyrosine            2.3         18           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo... 
ARHGEF7               0.528   PAK-interacting exchange factor beta isoform b [Homo...
ARHGEF7               0.520   PAK-interacting exchange factor beta isoform c [Hom...
ARHGEF7               0.512   PAK-interacting exchange factor beta isoform a [Hom...
ARHGEF7               0.512   PAK-interacting exchange factor beta isoform a 
ARHGEF7               0.500   PAK-interacting exchange factor beta isoform d [Hom...
PLEKHG1               0.059   pleckstrin homology domain containing, family G (wit...
SPATA13               0.057   spermatogenesis associated 13 
ARHGEF4               0.055   Rho guanine nucleotide exchange factor 4 isoform a [...
ARHGEF4               0.055   Rho guanine nucleotide exchange factor 4 isoform b [...
ITSN1                 0.049   intersectin 1 isoform ITSN-l 
PREX1                 0.049   phosphatidylinositol-3,4,5-trisphosphate-dependent R...
ITSN2                 0.049   intersectin 2 isoform 3 
ITSN2                 0.049   intersectin 2 isoform 1 
PLEKHG2               0.043   common-site lymphoma/leukemia guanine nucleotide ex...
ARHGEF9               0.042   Cdc42 guanine exchange factor 9 
PREX2                 0.041   DEP domain containing 2 isoform b 
PREX2                 0.041   DEP domain containing 2 isoform a 
TIAM2                 0.040   T-cell lymphoma invasion and metastasis 2 isoform b ...
TIAM2                 0.040   T-cell lymphoma invasion and metastasis 2 isoform a ...
TRIO                  0.040   triple functional domain (PTPRF interacting) 
KALRN                 0.039   kalirin, RhoGEF kinase isoform 1 
KALRN                 0.039   kalirin, RhoGEF kinase isoform 2 
VAV3                  0.034   vav 3 guanine nucleotide exchange factor isoform 1 ...
TIAM1                 0.034   T-cell lymphoma invasion and metastasis 1 
ARHGEF17              0.032   Rho guanine nucleotide exchange factor (GEF) 17 [Hom...
VAV2                  0.031   vav 2 guanine nucleotide exchange factor isoform 1 ...
FGD4                  0.030   FYVE, RhoGEF and PH domain containing 4 
PLEKHG3               0.030   pleckstrin homology domain containing, family G, mem...
SH3KBP1               0.030   SH3-domain kinase binding protein 1 isoform a 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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