Guide to the Human Genome
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Name: ARHGEF7 Sequence: fasta or formatted (646aa) NCBI GI: 4505573
Description:

PAK-interacting exchange factor beta isoform a

Referenced in:

Rho and Rac

Other entries for this name:
alt prot [803aa] PAK-interacting exchange factor beta isoform c
alt prot [753aa] PAK-interacting exchange factor beta isoform d
alt mRNA [646aa] PAK-interacting exchange factor beta isoform a
alt prot [782aa] PAK-interacting exchange factor beta isoform b
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.8         31           2
 C cysteine            1.5         10           1
 D aspartate           3.4         22           2
 E glutamate           9.6         62           3
 F phenylalanine       2.2         14           1
 G glycine             4.0         26           2
 H histidine           2.5         16           2
 I isoleucine          3.6         23           2
 K lysine              8.5         55           2
 L leucine            10.8         70           3
 M methionine          2.6         17           1
 N asparagine          5.1         33           2
 P proline             6.7         43           2
 Q glutamine           5.0         32           2
 R arginine            4.2         27           1
 S serine              8.8         57           3
 T threonine           7.4         48           2
 V valine              5.4         35           2
 W tryptophan          1.2          8           2
 Y tyrosine            2.6         17           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   PAK-interacting exchange factor beta isoform a 
ARHGEF7               1.000   PAK-interacting exchange factor beta isoform a [Hom...
ARHGEF7               0.863   PAK-interacting exchange factor beta isoform d [Hom...
ARHGEF7               0.863   PAK-interacting exchange factor beta isoform c [Hom...
ARHGEF7               0.863   PAK-interacting exchange factor beta isoform b [Homo...
ARHGEF6               0.611   Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo...
ARHGEF4               0.084   Rho guanine nucleotide exchange factor 4 isoform a [...
ARHGEF4               0.084   Rho guanine nucleotide exchange factor 4 isoform b [...
SPATA13               0.076   spermatogenesis associated 13 
PLEKHG1               0.072   pleckstrin homology domain containing, family G (wit...
ARHGEF9               0.066   Cdc42 guanine exchange factor 9 
ITSN2                 0.064   intersectin 2 isoform 3 
ITSN2                 0.064   intersectin 2 isoform 1 
ITSN1                 0.061   intersectin 1 isoform ITSN-l 
PREX1                 0.058   phosphatidylinositol-3,4,5-trisphosphate-dependent R...
PREX2                 0.056   DEP domain containing 2 isoform b 
PREX2                 0.056   DEP domain containing 2 isoform a 
FARP1                 0.049   FERM, RhoGEF, and pleckstrin domain protein 1 isoform...
PLEKHG2               0.048   common-site lymphoma/leukemia guanine nucleotide ex...
FGD4                  0.042   FYVE, RhoGEF and PH domain containing 4 
FARP2                 0.042   FERM, RhoGEF and pleckstrin domain protein 2 
TRIO                  0.042   triple functional domain (PTPRF interacting) 
KALRN                 0.042   kalirin, RhoGEF kinase isoform 1 
KALRN                 0.042   kalirin, RhoGEF kinase isoform 2 
TIAM1                 0.042   T-cell lymphoma invasion and metastasis 1 
TIAM2                 0.042   T-cell lymphoma invasion and metastasis 2 isoform b ...
TIAM2                 0.042   T-cell lymphoma invasion and metastasis 2 isoform a ...
DNMBP                 0.038   dynamin binding protein 
PLEKHG3               0.038   pleckstrin homology domain containing, family G, mem...
SH3KBP1               0.037   SH3-domain kinase binding protein 1 isoform a 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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