Search of human proteins with 23510323

Search of human proteins with 23510323

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23510323 nephroretinin [Homo sapiens]
         (1426 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23510323 nephroretinin [Homo sapiens]                             2868   0.0  
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              46   2e-04
gi|27502386 nuclear factor of activated T-cells, cytosolic compo...    45   4e-04
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi...    45   5e-04
gi|54860079 nadrin isoform 1 [Homo sapiens]                            44   0.001
gi|15451844 ADAM metallopeptidase domain 19 preproprotein [Homo ...    43   0.002
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         43   0.002
gi|13129104 coiled-coil domain containing 86 [Homo sapiens]            43   0.002
gi|222352122 hypothetical protein LOC284297 [Homo sapiens]             40   0.012
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    40   0.012
gi|157785645 SPEG complex locus [Homo sapiens]                         40   0.012
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    40   0.016
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    40   0.016
gi|54860105 nadrin isoform 2 [Homo sapiens]                            40   0.016
gi|111955326 MLX interacting protein [Homo sapiens]                    40   0.016
gi|194578898 hypothetical protein LOC100170841 [Homo sapiens]          40   0.016
gi|236459851 ubinuclein 2 [Homo sapiens]                               39   0.027
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    39   0.027
gi|197313748 SET domain containing 2 [Homo sapiens]                    39   0.027
gi|5802980 activating transcription factor 7 isoform 2 [Homo sap...    39   0.036
gi|166706868 synaptopodin 2-like isoform a [Homo sapiens]              39   0.036
gi|46276868 hypothetical protein LOC9710 [Homo sapiens]                39   0.036
gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo ...    39   0.047
gi|149944516 tet oncogene family member 3 [Homo sapiens]               39   0.047
gi|56549696 E1A binding protein p400 [Homo sapiens]                    39   0.047
gi|194239640 activating transcription factor 7 isoform 1 [Homo s...    39   0.047
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    39   0.047
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             38   0.061
gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens]       38   0.061
gi|27477095 nuclear receptor binding SET domain protein 1 isofor...    38   0.061

>gi|23510323 nephroretinin [Homo sapiens]
          Length = 1426

 Score = 2868 bits (7435), Expect = 0.0
 Identities = 1426/1426 (100%), Positives = 1426/1426 (100%)

Query: 1    MNDWHRIFTQNVLVPPHPQRARQPWKESTAFQCVLKWLDGPVIRQGVLEVLSEVECHLRV 60
            MNDWHRIFTQNVLVPPHPQRARQPWKESTAFQCVLKWLDGPVIRQGVLEVLSEVECHLRV
Sbjct: 1    MNDWHRIFTQNVLVPPHPQRARQPWKESTAFQCVLKWLDGPVIRQGVLEVLSEVECHLRV 60

Query: 61   SFFDVTYRHFFGRTWKTTVKPTKRPPSRIVFNEPLYFHTSLNHPHIVAVVEVVAEGKKRD 120
            SFFDVTYRHFFGRTWKTTVKPTKRPPSRIVFNEPLYFHTSLNHPHIVAVVEVVAEGKKRD
Sbjct: 61   SFFDVTYRHFFGRTWKTTVKPTKRPPSRIVFNEPLYFHTSLNHPHIVAVVEVVAEGKKRD 120

Query: 121  GSLQTLSCGFGILRIFSNQPDSPISASQDKRLRLYHGTPRALLHPLLQDPAEQNRHMTLI 180
            GSLQTLSCGFGILRIFSNQPDSPISASQDKRLRLYHGTPRALLHPLLQDPAEQNRHMTLI
Sbjct: 121  GSLQTLSCGFGILRIFSNQPDSPISASQDKRLRLYHGTPRALLHPLLQDPAEQNRHMTLI 180

Query: 181  ENCSLQYTLKPHPALEPAFHLLPENLLVSGLQQIPGLLPAHGESGDALRKPRLQKPITGH 240
            ENCSLQYTLKPHPALEPAFHLLPENLLVSGLQQIPGLLPAHGESGDALRKPRLQKPITGH
Sbjct: 181  ENCSLQYTLKPHPALEPAFHLLPENLLVSGLQQIPGLLPAHGESGDALRKPRLQKPITGH 240

Query: 241  LDDLFFTLYPSLEKFEEELLELHVQDHFQEGCGPLDGGALEILERRLRVGVHNGLGFVQR 300
            LDDLFFTLYPSLEKFEEELLELHVQDHFQEGCGPLDGGALEILERRLRVGVHNGLGFVQR
Sbjct: 241  LDDLFFTLYPSLEKFEEELLELHVQDHFQEGCGPLDGGALEILERRLRVGVHNGLGFVQR 300

Query: 301  PQVVVLVPEMDVALTRSASFSRKVVSSSKTSSGSQALVLRSRLRLPEMVGHPAFAVIFQL 360
            PQVVVLVPEMDVALTRSASFSRKVVSSSKTSSGSQALVLRSRLRLPEMVGHPAFAVIFQL
Sbjct: 301  PQVVVLVPEMDVALTRSASFSRKVVSSSKTSSGSQALVLRSRLRLPEMVGHPAFAVIFQL 360

Query: 361  EYVFSSPAGVDGNAASVTSLSNLACMHMVRWAVWNPLLEADSGRVTLPLQGGIQPNPSHC 420
            EYVFSSPAGVDGNAASVTSLSNLACMHMVRWAVWNPLLEADSGRVTLPLQGGIQPNPSHC
Sbjct: 361  EYVFSSPAGVDGNAASVTSLSNLACMHMVRWAVWNPLLEADSGRVTLPLQGGIQPNPSHC 420

Query: 421  LVYKVPSASMSSEEVKQVESGTLRFQFSLGSEEHLDAPTEPVSGPKVERRPSRKPPTSPS 480
            LVYKVPSASMSSEEVKQVESGTLRFQFSLGSEEHLDAPTEPVSGPKVERRPSRKPPTSPS
Sbjct: 421  LVYKVPSASMSSEEVKQVESGTLRFQFSLGSEEHLDAPTEPVSGPKVERRPSRKPPTSPS 480

Query: 481  SPPAPVPRVLAAPQNSPVGPGLSISQLAASPRSPTQHCLARPTSQLPHGSQASPAQAQEF 540
            SPPAPVPRVLAAPQNSPVGPGLSISQLAASPRSPTQHCLARPTSQLPHGSQASPAQAQEF
Sbjct: 481  SPPAPVPRVLAAPQNSPVGPGLSISQLAASPRSPTQHCLARPTSQLPHGSQASPAQAQEF 540

Query: 541  PLEAGISHLEADLSQTSLVLETSIAEQLQELPFTPLHAPIVVGTQTRSSAGQPSRASMVL 600
            PLEAGISHLEADLSQTSLVLETSIAEQLQELPFTPLHAPIVVGTQTRSSAGQPSRASMVL
Sbjct: 541  PLEAGISHLEADLSQTSLVLETSIAEQLQELPFTPLHAPIVVGTQTRSSAGQPSRASMVL 600

Query: 601  LQSSGFPEILDANKQPAEAVSATEPVTFNPQKEESDCLQSNEMVLQFLAFSRVAQDCRGT 660
            LQSSGFPEILDANKQPAEAVSATEPVTFNPQKEESDCLQSNEMVLQFLAFSRVAQDCRGT
Sbjct: 601  LQSSGFPEILDANKQPAEAVSATEPVTFNPQKEESDCLQSNEMVLQFLAFSRVAQDCRGT 660

Query: 661  SWPKTVYFTFQFYRFPPATTPRLQLVQLDEAGQPSSGALTHILVPVSRDGTFDAGSPGFQ 720
            SWPKTVYFTFQFYRFPPATTPRLQLVQLDEAGQPSSGALTHILVPVSRDGTFDAGSPGFQ
Sbjct: 661  SWPKTVYFTFQFYRFPPATTPRLQLVQLDEAGQPSSGALTHILVPVSRDGTFDAGSPGFQ 720

Query: 721  LRYMVGPGFLKPGERRCFARYLAVQTLQIDVWDGDSLLLIGSAAVQMKHLLRQGRPAVQA 780
            LRYMVGPGFLKPGERRCFARYLAVQTLQIDVWDGDSLLLIGSAAVQMKHLLRQGRPAVQA
Sbjct: 721  LRYMVGPGFLKPGERRCFARYLAVQTLQIDVWDGDSLLLIGSAAVQMKHLLRQGRPAVQA 780

Query: 781  SHELEVVATEYEQDNMVVSGDMLGFGRVKPIGVHSVVKGRLHLTLANVGHPCEQKVRGCS 840
            SHELEVVATEYEQDNMVVSGDMLGFGRVKPIGVHSVVKGRLHLTLANVGHPCEQKVRGCS
Sbjct: 781  SHELEVVATEYEQDNMVVSGDMLGFGRVKPIGVHSVVKGRLHLTLANVGHPCEQKVRGCS 840

Query: 841  TLPPSRSRVISNDGASRFSGGSLLTTGSSRRKHVVQAQKLADVDSELAAMLLTHARQGKG 900
            TLPPSRSRVISNDGASRFSGGSLLTTGSSRRKHVVQAQKLADVDSELAAMLLTHARQGKG
Sbjct: 841  TLPPSRSRVISNDGASRFSGGSLLTTGSSRRKHVVQAQKLADVDSELAAMLLTHARQGKG 900

Query: 901  PQDVSRESDATRRRKLERMRSVRLQEAGGDLGRRGTSVLAQQSVRTQHLRDLQVIAAYRE 960
            PQDVSRESDATRRRKLERMRSVRLQEAGGDLGRRGTSVLAQQSVRTQHLRDLQVIAAYRE
Sbjct: 901  PQDVSRESDATRRRKLERMRSVRLQEAGGDLGRRGTSVLAQQSVRTQHLRDLQVIAAYRE 960

Query: 961  RTKAESIASLLSLAITTEHTLHATLGVAEFFEFVLKNPHNTQHTVTVEIDNPELSVIVDS 1020
            RTKAESIASLLSLAITTEHTLHATLGVAEFFEFVLKNPHNTQHTVTVEIDNPELSVIVDS
Sbjct: 961  RTKAESIASLLSLAITTEHTLHATLGVAEFFEFVLKNPHNTQHTVTVEIDNPELSVIVDS 1020

Query: 1021 QEWRDFKGAAGLHTPVEEDMFHLRGSLAPQLYLRPHETAHVPFKFQSFSAGQLAMVQASP 1080
            QEWRDFKGAAGLHTPVEEDMFHLRGSLAPQLYLRPHETAHVPFKFQSFSAGQLAMVQASP
Sbjct: 1021 QEWRDFKGAAGLHTPVEEDMFHLRGSLAPQLYLRPHETAHVPFKFQSFSAGQLAMVQASP 1080

Query: 1081 GLSNEKGMDAVSPWKSSAVPTKHAKVLFRASGGKPIAVLCLTVELQPHVVDQVFRFYHPE 1140
            GLSNEKGMDAVSPWKSSAVPTKHAKVLFRASGGKPIAVLCLTVELQPHVVDQVFRFYHPE
Sbjct: 1081 GLSNEKGMDAVSPWKSSAVPTKHAKVLFRASGGKPIAVLCLTVELQPHVVDQVFRFYHPE 1140

Query: 1141 LSFLKKAIRLPPWHTFPGAPVGMLGEDPPVHVRCSDPNVICETQNVGPGEPRDIFLKVAS 1200
            LSFLKKAIRLPPWHTFPGAPVGMLGEDPPVHVRCSDPNVICETQNVGPGEPRDIFLKVAS
Sbjct: 1141 LSFLKKAIRLPPWHTFPGAPVGMLGEDPPVHVRCSDPNVICETQNVGPGEPRDIFLKVAS 1200

Query: 1201 GPSPEIKDFFVIIYSDRWLATPTQTWQVYLHSLQRVDVSCVAGQLTRLSLVLRGTQTVRK 1260
            GPSPEIKDFFVIIYSDRWLATPTQTWQVYLHSLQRVDVSCVAGQLTRLSLVLRGTQTVRK
Sbjct: 1201 GPSPEIKDFFVIIYSDRWLATPTQTWQVYLHSLQRVDVSCVAGQLTRLSLVLRGTQTVRK 1260

Query: 1261 VRAFTSHPQELKTDPKGVFVLPPRGVQDLHVGVRPLRAGSRFVHLNLVDVDCHQLVASWL 1320
            VRAFTSHPQELKTDPKGVFVLPPRGVQDLHVGVRPLRAGSRFVHLNLVDVDCHQLVASWL
Sbjct: 1261 VRAFTSHPQELKTDPKGVFVLPPRGVQDLHVGVRPLRAGSRFVHLNLVDVDCHQLVASWL 1320

Query: 1321 VCLCCRQPLISKAFEIMLAAGEGKGVNKRITYTNPYPSRRTFHLHSDHPELLRFREDSFQ 1380
            VCLCCRQPLISKAFEIMLAAGEGKGVNKRITYTNPYPSRRTFHLHSDHPELLRFREDSFQ
Sbjct: 1321 VCLCCRQPLISKAFEIMLAAGEGKGVNKRITYTNPYPSRRTFHLHSDHPELLRFREDSFQ 1380

Query: 1381 VGGGETYTIGLQFAPSQRVGEEEILIYINDHEDKNEEAFCVKVIYQ 1426
            VGGGETYTIGLQFAPSQRVGEEEILIYINDHEDKNEEAFCVKVIYQ
Sbjct: 1381 VGGGETYTIGLQFAPSQRVGEEEILIYINDHEDKNEEAFCVKVIYQ 1426


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 69/283 (24%), Positives = 99/283 (34%), Gaps = 50/283 (17%)

Query: 400 ADSGRVTLPLQG----------GIQPNPSHCLVYKVPSASMSSEEVKQVESGT------- 442
           + SG  TLP +G             P P      + P AS+SS       S +       
Sbjct: 586 SQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDR 645

Query: 443 --------LRFQFSLGSEEHLDAPTEPVSGPKVERRPSRKPPTSPSSPPAPVPRVLAAPQ 494
                   L  +F +     + AP  P         P+     +P+  P PV    A+PQ
Sbjct: 646 SGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQ 705

Query: 495 NSPVGPGLSISQLAASP-----------RSPTQHCLARPTS------QLPHGSQAS--PA 535
           + P  P  +++ L  SP             P+ H    PT       + P  S+ +  P 
Sbjct: 706 SPPT-PQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPL 764

Query: 536 QAQEFPLEAGISHLEADLSQTSLVL-ETSIAEQLQELPFTPLHAPIVVGTQTRSSAGQPS 594
           Q   +P     +  E DLS       E +        P  P  +P +V +   SS    S
Sbjct: 765 QDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASS----S 820

Query: 595 RASMVLLQSSGFPEILDANKQPAEAVSATEPVTFNPQKEESDC 637
            A+ + +Q  G P+   A   PA A SA   V   PQKE   C
Sbjct: 821 SATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGC 863



 Score = 33.5 bits (75), Expect = 1.5
 Identities = 30/116 (25%), Positives = 45/116 (38%), Gaps = 24/116 (20%)

Query: 437  QVESGTLRFQFSLGSEE-HLDAPTEPVSGPKVER------------RPSRKPPTSPSSPP 483
            Q  + T  F FS GS +  L+ P  P +   ++R            RP + P  SP +PP
Sbjct: 964  QSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPP 1023

Query: 484  APVPRVLAAPQNSPVGPGLSISQLAASPRSPTQHCLARPTSQLPHGSQASPAQAQE 539
             PV R  +     P  P    ++   +P          PT+ LPH    +  +  E
Sbjct: 1024 -PVARKPSVGVPPPASPSYPRAEPLTAP----------PTNGLPHTQDRTKRELAE 1068


>gi|27502386 nuclear factor of activated T-cells, cytosolic
           component 1 isoform C [Homo sapiens]
          Length = 930

 Score = 45.4 bits (106), Expect = 4e-04
 Identities = 43/165 (26%), Positives = 64/165 (38%), Gaps = 13/165 (7%)

Query: 410 QGGIQPNPSHCLVYK----------VPSASMSSEEVKQVESGTLRFQFSLGSEEHLDAPT 459
           Q  + P+PS CLV            +P+A   S ++  +         +     HL  P 
Sbjct: 720 QLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQ 779

Query: 460 EPVSGPKVER--RPSRKPPTSPSSPP-APVPRVLAAPQNSPVGPGLSISQLAASPRSPTQ 516
                P V+   RP    P SP  PP A +P+ ++AP +S   PGL  S   +SP  P  
Sbjct: 780 PAGEAPAVQDVPRPVATHPGSPGQPPPALLPQQVSAPPSSSCPPGLEHSLCPSSPSPPLP 839

Query: 517 HCLARPTSQLPHGSQASPAQAQEFPLEAGISHLEADLSQTSLVLE 561
                PT   P      PA  +   L + +   E+  +   L+ E
Sbjct: 840 PATQEPTCLQPCSPACPPATGRPQHLPSTVRRDESPTAGPRLLPE 884


>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 673

 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 91/370 (24%), Positives = 129/370 (34%), Gaps = 43/370 (11%)

Query: 365 SSPAGVDGNAASVTSLSNLACMHMVRWAVWNPLLEADSGRVTLPLQGGIQPNPSHCLVYK 424
           +SP G    A+   + S  + M M+  A    +L   S    +     I   P    + +
Sbjct: 284 ASPTGTPSRASLSMTPSTASLMRMLPRASPTGMLSRTS-LTKMDSTASISRTPPRASITR 342

Query: 425 VPS-ASMSSEEVKQVESGTLRFQFSLGSEEHLDAPTEPVSGPKVERRPSRKPP-TSPSSP 482
            PS AS + +      +GT       GS       T  ++G      P+  PP  SP+  
Sbjct: 343 TPSRASPTGKPSTASPTGTPSRASPTGSPS-----TASLTGLSSTASPTGTPPRASPTGT 397

Query: 483 PAPVPRVLAAPQNSPVG--PGLSISQL--AASP-RSPTQHCLARPTSQLPHGS------Q 531
           P+        P+ SP G     SI+++   ASP R+P +   A PT   P  S      +
Sbjct: 398 PSTASLTRKPPRASPTGMLSRTSITKMDSTASPTRTPPR---ASPTGTPPRASPTGTPSR 454

Query: 532 ASPAQAQEFPLEAGISHLEADLSQTSLVLETSIAEQLQELPFTPLHAPIVVGTQTRSSAG 591
           ASP   Q      G     +     S    T    +   L  TP  A +     T S   
Sbjct: 455 ASPTGTQSTASPTGSPSTASPTGSPSTASPTGSPSRAS-LTRTPSRASLTKMESTASITR 513

Query: 592 QPSRASMVLLQSSGFPEILDANKQPAEAVSATEP----VTFNPQKEESDCLQSNEMVLQF 647
            PSRAS     S+  P        P+ A++   P    +T  P +     L         
Sbjct: 514 TPSRASPTWTPSTASP-----TGSPSTALAMGSPSRAALTRTPSRAS---LTRTPSRASL 565

Query: 648 LAFSRVAQDCRGTSWPKTVYFTFQFYRFPPATTPRLQLVQLDEAGQPSSGALTHILVPVS 707
              SR +     T  P TV  T    R PP+ +P     +    G PSS  LT +    S
Sbjct: 566 TTPSRASL----TRTPSTVLLT----RMPPSASPTGMPSRTSPTGMPSSALLTKMDSTAS 617

Query: 708 RDGTFDAGSP 717
              T    SP
Sbjct: 618 ITRTPPRASP 627


>gi|54860079 nadrin isoform 1 [Homo sapiens]
          Length = 881

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 46/170 (27%), Positives = 64/170 (37%), Gaps = 32/170 (18%)

Query: 399 EADSGRVTLPLQGGI-----------QPNPSHCLVYKVPSASMSSEEV----KQVESGTL 443
           E+ SG  T+P   GI            P P   +   VP+   ++ ++     Q ++   
Sbjct: 550 ESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAG 609

Query: 444 RFQFSLGSEEHLDAPTEPVSGPKVERRPSRKP---PTSPSSPPAPVPRVLAAPQNSPVGP 500
             Q S+G   +   P+     P   RR  +KP   P  P +PP   P   ++   S   P
Sbjct: 610 SHQLSMGQPHNAAGPS-----PHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPP 664

Query: 501 GLSISQLAASPRSPTQHCLARP-----TSQLP----HGSQASPAQAQEFP 541
            LS      SP  PTQH    P      SQL     + S  SP QA   P
Sbjct: 665 SLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHP 714


>gi|15451844 ADAM metallopeptidase domain 19 preproprotein [Homo
           sapiens]
          Length = 918

 Score = 43.1 bits (100), Expect = 0.002
 Identities = 28/74 (37%), Positives = 41/74 (55%), Gaps = 12/74 (16%)

Query: 462 VSGPKVERRPSRKPPTSP------SSPPAPVPRVLA-APQNSPVGPGLSISQLAASPRSP 514
           ++ P++ R+PS+ PP  P       SPPAP+P  L+ A +NSP GPG  I +  +S R P
Sbjct: 777 INTPEILRKPSQPPPRPPPDYLRGGSPPAPLPAHLSRAARNSP-GPGSQIERTESSRRPP 835

Query: 515 TQHCLARPTSQLPH 528
                +RP    P+
Sbjct: 836 P----SRPIPPAPN 845


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 43.1 bits (100), Expect = 0.002
 Identities = 57/223 (25%), Positives = 86/223 (38%), Gaps = 32/223 (14%)

Query: 425  VPSASMSSEEVKQVESGTLRFQFSLGSEEHLDAP-----TEPVSGPKVERRP------SR 473
            +P++S  +  V    S  L     +     L AP     T P+S P            S 
Sbjct: 1417 IPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSV 1476

Query: 474  KPPTSPSSPPAPVPRVL----AAPQNSPVGPGLSISQLAASPRSPTQHCLARPTSQLPHG 529
             PP +P  P AP P  L    A+P  S +  GL+ +   +S ++P    L  PTS    G
Sbjct: 1477 TPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPG 1536

Query: 530  SQAS----------PAQAQEFPLEAGISHLEADLSQTSLVLETSIAEQLQELPFTPLHAP 579
              ++          PA A   P  +  +   A   Q SL+   S A Q    P  P+ AP
Sbjct: 1537 LNSTVAPACSPVLVPASALASPFPSAPNPAPA---QASLLAPASSASQALATPLAPMAAP 1593

Query: 580  IVVGTQTRSSAGQPSRASM-VLLQSSGFPEILDANKQPAEAVS 621
                T   + +  P  A + VL  S G   +L +++ P   ++
Sbjct: 1594 ---QTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMA 1633



 Score = 36.6 bits (83), Expect = 0.18
 Identities = 52/223 (23%), Positives = 79/223 (35%), Gaps = 53/223 (23%)

Query: 459  TEPVSGPKVER--RPSRKPPTSPSSPPAPVPRVLAAPQNSPV------------------ 498
            T P   P  ER  RP+ +P  +P+S PA +P ++  P ++PV                  
Sbjct: 2425 TPPRCSPARERVPRPAPRPRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPS 2484

Query: 499  ---------------GPGLSISQLAASPRSPTQHCLARPTSQLPHGSQASPAQAQEFPLE 543
                            P  + +   A    P Q CL  P+S L  G  + P  A    L 
Sbjct: 2485 PPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLP 2544

Query: 544  AGISHLEADL------SQTSLVLETSIAEQLQELPFTP----LHAPIVVGTQTRSSAGQP 593
             G+   EA+L      S  SL L +  + +   L   P    L   + +   +  +    
Sbjct: 2545 LGL-RPEAELCAQALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLT 2603

Query: 594  SRASMVLLQSSGFPEILDANKQPAEAVSATEPVTFN--PQKEE 634
              A  + L++   P     N Q  EA  + E  T    P+ EE
Sbjct: 2604 PSAPSLTLEAGSIP-----NGQEQEAPDSAEGTTLTVLPEGEE 2641



 Score = 31.2 bits (69), Expect = 7.5
 Identities = 45/195 (23%), Positives = 63/195 (32%), Gaps = 18/195 (9%)

Query: 457  APTEPVSGPKVERRPSRKPPTSPSSPPAPVP------RVLAAPQNSPVGPGLSISQLAAS 510
            A   PV  P     PS      P+  P+P+P       +  AP  +P   G S SQ  + 
Sbjct: 1643 ASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSL 1702

Query: 511  PRSPTQHCLARPTSQLPHGSQASPAQAQEFPLEAGISHLEADLSQTSLVLETSIAEQLQE 570
                 Q      T  L   S   P  AQ   L  G       L  T  +           
Sbjct: 1703 GTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPG-----PPLGPTQTLSLAPAPPLAPA 1757

Query: 571  LPFTPLHAPIVVGTQTRSSAGQPSRASMVLLQSSGFPEILDANKQPAEAVSATEPVTFNP 630
             P  P  A  +      SSA   + AS+  L  S  P        P    +A + +   P
Sbjct: 1758 SPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAP-------VPTLGPAAAQTLALAP 1810

Query: 631  QKEESDCLQSNEMVL 645
               +S   Q++ +V+
Sbjct: 1811 ASTQSPASQASSLVV 1825


>gi|13129104 coiled-coil domain containing 86 [Homo sapiens]
          Length = 360

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 58/206 (28%), Positives = 84/206 (40%), Gaps = 37/206 (17%)

Query: 452 EEHLDAPTEPVSGPKVERR----PSRKPPTSPSSPPAPVPRVLAAPQNSPVGPGLSISQL 507
           E + +   EP S P V+R     P R P TSP SP       L +PQ  P  PG      
Sbjct: 36  ESNPEETREPGSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQP-EPG------ 88

Query: 508 AASPRSPTQHCLARPTSQ---LPHGSQASPAQAQEFPLEAGISHLEADLSQTSLVLETSI 564
           AASP+      L  P  Q    P   +  P  ++E P            SQ   VL + +
Sbjct: 89  AASPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAP----------KCSQDQGVLASEL 138

Query: 565 AEQLQEL-PFTPLH-APIVVGTQ-----TRSSAGQPSRASMVLL-QSSGFPEILDANKQP 616
           A+  +EL P  P H  P V G+       ++   +PS+  + L  ++ G P       +P
Sbjct: 139 AQNKEELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPR---GQHEP 195

Query: 617 AEAVSATEPVT--FNPQKEESDCLQS 640
           ++   A E VT  F  +K +    Q+
Sbjct: 196 SKPPPAGETVTGGFGAKKRKGSSSQA 221


>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
          Length = 1573

 Score = 40.4 bits (93), Expect = 0.012
 Identities = 39/152 (25%), Positives = 59/152 (38%), Gaps = 14/152 (9%)

Query: 465  PKVERRPSRKPPTSPSSPPAPVPRVLAAPQNSPVGPGLSISQLAASPRSPTQHCLARPTS 524
            P  ERRP R P  + ++PP P P     P  SP  PG +++  ++   +P     +  TS
Sbjct: 988  PWPERRPPR-PAATRTAPPTPSP----GPSASPGPPGPALTSDSSRELTPHSALTSEATS 1042

Query: 525  QLPHGSQASPAQAQEFPLEAGISHLEADLSQTSLVLETSIAEQLQELPFTPLHAPIVVGT 584
              P  S  +P  A         S    DL  TS     S  +       TP  +P  + T
Sbjct: 1043 DAPDTSPPTPDPA---------SRTNPDLILTSPDFALSTPDSSVVPALTPEPSPTPLPT 1093

Query: 585  QTRSSAGQPSRASMVLLQSSGFPEILDANKQP 616
              +     PS  S V   S    ++ +++  P
Sbjct: 1094 LPKELTSDPSTPSEVTSLSPTSEQVPESDTTP 1125


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 40.4 bits (93), Expect = 0.012
 Identities = 41/131 (31%), Positives = 54/131 (41%), Gaps = 17/131 (12%)

Query: 452 EEHLDAPTE---PVSGPKVERRPSRKPPTSPSSPPAPVPRVLAAPQNSPVGP---GLSIS 505
           E  L+AP     P+  P  E   S  P  SP+SPP    R+   P+  P  P    L +S
Sbjct: 427 EPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLS 486

Query: 506 Q-LAASPRSPTQHCLARPTSQLPHGSQASPAQAQEFPLEAGISHLEADLSQTSLVLETSI 564
           + L  SP SP       P S  P  S  SP   +E PL         + S  S  LET +
Sbjct: 487 RPLEESPLSPPPE--ESPLSPPPESSPFSP--LEESPLS------PPEESPPSPALETPL 536

Query: 565 AEQLQELPFTP 575
           +   +  P +P
Sbjct: 537 SPPPEASPLSP 547



 Score = 38.1 bits (87), Expect = 0.061
 Identities = 40/152 (26%), Positives = 63/152 (41%), Gaps = 16/152 (10%)

Query: 446  QFSLGSEEHLDAPTEPVSGPKVERRPSRKPPTSPSSPPAPVPRVLAAPQ-NSPVGPGLSI 504
            ++  G++   D P  P++ P +E  P   PP +  + P PVP ++  P   SPVGP   I
Sbjct: 958  EYPFGAKGDSD-PESPLAAPILET-PISPPPEANCTDPEPVPPMILPPSPGSPVGPASPI 1015

Query: 505  SQLAASPR-SP-TQHCLARPTSQLPHGSQASPAQAQEFPLEAGISHLEADLSQTSLVLET 562
                  P+ SP  QH L      +P  S  S       PL      + + LS    V+  
Sbjct: 1016 LMEPLPPQCSPLLQHSL------VPQNSPPSQCSPPALPLS-----VPSPLSPIGKVVGV 1064

Query: 563  SIAEQLQELPFTPLHAPIVVGTQTRSSAGQPS 594
            S   +L E+    +  P     +  +++  PS
Sbjct: 1065 SDEAELHEMETEKVSEPECPALEPSATSPLPS 1096



 Score = 36.6 bits (83), Expect = 0.18
 Identities = 40/140 (28%), Positives = 55/140 (39%), Gaps = 31/140 (22%)

Query: 452 EEHLDAPTE--PVSGPKVERRPSRKPPTSPSSPPAPVPRVLAAPQNSPVGPGLSISQLA- 508
           E  L  P E  P+S P    R S  P  SP SPP         P+ SP+ P   +S+L+ 
Sbjct: 605 ESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPP---------PEESPMSPPPEVSRLSP 655

Query: 509 ------------ASPRSPTQHCLARPTSQLPHGSQASPAQAQEFPLEAGISHLEADLSQT 556
                        SP SP       PTS  P  S+ SP      P ++  S    D   +
Sbjct: 656 LPVVSRLSPPPEESPLSPPPE--ESPTSPPPEASRLSPP-----PEDSPTSPPPEDSPAS 708

Query: 557 SLVLETSIAEQLQELPFTPL 576
               ++ ++  L+E P  PL
Sbjct: 709 PPPEDSLMSLPLEESPLLPL 728



 Score = 36.6 bits (83), Expect = 0.18
 Identities = 48/181 (26%), Positives = 66/181 (36%), Gaps = 24/181 (13%)

Query: 459  TEPVSGPKVERRPSRKPPTS------PSSPPAPVPRVLAAPQN-----SPVGP-GLSISQ 506
            T+P + P +  RP   PP S       S P  P  RV A+PQ+     SP+ P  LS   
Sbjct: 2375 TDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEA 2434

Query: 507  LAASPRSP---TQHCLARPTSQLPHGSQASPAQAQEFPLEAGISHLEADLSQTSLVLETS 563
               SP +P   +    +RP S+       +P      P    ++     L+ TSL     
Sbjct: 2435 FCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLG-AGG 2493

Query: 564  IAEQLQELPFTPLHAPIVVGTQ--------TRSSAGQPSRASMVLLQSSGFPEILDANKQ 615
                L   P   LHA +  G          T +  G PS       Q+ G P +     Q
Sbjct: 2494 FPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQ 2553

Query: 616  P 616
            P
Sbjct: 2554 P 2554



 Score = 35.8 bits (81), Expect = 0.30
 Identities = 32/100 (32%), Positives = 39/100 (39%), Gaps = 7/100 (7%)

Query: 447 FSLGSEEHLDAPTEPVSGPKVERRPSRKPPTSPSSPPAPVPRVLAAPQNSPVGPGLSISQ 506
           FS   E  L  P E    P +E   S  P  SP SPP     +   P+  P  P    S+
Sbjct: 512 FSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASR 571

Query: 507 LA----ASPRSPTQHCLARPTSQLPHGSQASPAQAQEFPL 542
           L+     SP SP       P S  P  S+  P   +E PL
Sbjct: 572 LSPPPEESPMSPPPE--ESPMSPPPEASRLFP-PFEESPL 608



 Score = 33.9 bits (76), Expect = 1.1
 Identities = 46/206 (22%), Positives = 72/206 (34%), Gaps = 33/206 (16%)

Query: 458  PTEPVSGPKVERRP----SRKPPTSPSSPPAPVPRVLAAPQNSPVGPGLSISQLAASP-- 511
            P E    P++E+ P      KPP  P   PAP    L  P   P     S+S L   P  
Sbjct: 846  PEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEP-----SLSPLLGEPAL 900

Query: 512  RSPTQHCLARPTSQLPHGSQASPAQAQEF----PLEAGISHLEADLSQTSL----VLETS 563
              P +  L+    +LP      P+ + +     PL   +S +    +  +L     LE  
Sbjct: 901  SEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYP 960

Query: 564  IAEQLQELPFTPLHAPIV---VGTQTRSSAGQPSRASMVLLQSSGFPEILDANKQPAEAV 620
               +    P +PL API+   +     ++   P     ++L  S           P   V
Sbjct: 961  FGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPS-----------PGSPV 1009

Query: 621  SATEPVTFNPQKEESDCLQSNEMVLQ 646
                P+   P   +   L  + +V Q
Sbjct: 1010 GPASPILMEPLPPQCSPLLQHSLVPQ 1035



 Score = 32.7 bits (73), Expect = 2.6
 Identities = 45/193 (23%), Positives = 73/193 (37%), Gaps = 17/193 (8%)

Query: 456 DAPTEP------VSGPKVERRPSRKPPTSPSSPPAPVPRVLAAPQNSPVGPGLSISQLAA 509
           + PT P      +S P  E   S  P  SP SPP    R+    + SP+ P    S L+ 
Sbjct: 560 ELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSP 619

Query: 510 SPRS------PTQHCLARPTSQLPHGSQASPAQAQEFPLEAGIS--HLEADLSQTSLVLE 561
            P +      P    ++ P  + P       ++    P+ + +S    E+ LS       
Sbjct: 620 PPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESP 679

Query: 562 TSIAEQLQELPFTPLHAPIVVGTQTRSSAGQPSRASMVLLQSSGFPEILDANKQPAEAVS 621
           TS   +   L   P  +P     +  S A  P   S++ L     P +L   ++P +   
Sbjct: 680 TSPPPEASRLSPPPEDSPTSPPPED-SPASPPPEDSLMSLPLEESP-LLPLPEEP-QLCP 736

Query: 622 ATEPVTFNPQKEE 634
            +E    +P+ EE
Sbjct: 737 RSEGPHLSPRPEE 749



 Score = 32.0 bits (71), Expect = 4.4
 Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 13/82 (15%)

Query: 469  RRPSRKPPTSPSSPPAPVPRVLAAPQNSPV----------GPGLSISQLAASPRSPTQHC 518
            R+ S  PP  PS PP+P+    A+P   P+           P  S   LA+SP S     
Sbjct: 4904 RQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKP 4963

Query: 519  LARPTSQLPHGSQASPAQAQEF 540
             ARP  +   G  + P + +++
Sbjct: 4964 RARPPEE---GEDSRPPRLKKW 4982


>gi|157785645 SPEG complex locus [Homo sapiens]
          Length = 3267

 Score = 40.4 bits (93), Expect = 0.012
 Identities = 32/114 (28%), Positives = 52/114 (45%), Gaps = 15/114 (13%)

Query: 447  FSLGSEEHLDAPTEPVSGPKVERRPSR-KPPTSPSS------PPAPV-PRVLAAPQNSPV 498
            F  G+++    P+       V  RP+R +PP SP+S      P AP  P V  +P + P 
Sbjct: 2767 FVRGTQDSSAVPSAAHQEAPVTSRPARARPPDSPTSLAPPLAPAAPTPPSVTVSPSSPPT 2826

Query: 499  GPGLSISQLAA---SPRSPTQH----CLARPTSQLPHGSQASPAQAQEFPLEAG 545
             P  ++S L A    P++P +       ARP       +  +P++ + F L+ G
Sbjct: 2827 PPSQALSSLKAVGPPPQTPPRRHRGLQAARPAEPTLPSTHVTPSEPKPFVLDTG 2880



 Score = 38.5 bits (88), Expect = 0.047
 Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 2/77 (2%)

Query: 456  DAPTEPVSGPKVERRPSRKPPTSPSSPPAPVPRVL--AAPQNSPVGPGLSISQLAASPRS 513
            DAP  P   P  ++ P  +P    +S PAP P+ L   A   +P    +   QL+   + 
Sbjct: 2201 DAPQPPAPQPAQDKAPEPRPEPVRASKPAPPPQALQTLALPLTPYAQIIQSLQLSGHAQG 2260

Query: 514  PTQHCLARPTSQLPHGS 530
            P+Q   A P+   PH +
Sbjct: 2261 PSQGPAAPPSEPKPHAA 2277



 Score = 35.4 bits (80), Expect = 0.40
 Identities = 32/101 (31%), Positives = 43/101 (42%), Gaps = 20/101 (19%)

Query: 428 ASMSSEEVKQVESGTLRFQFSL----GSEEHLDAPT----------EPVSGPKVERRPSR 473
           AS  SE+   V S      FSL        H+  P           +P    +  RRP++
Sbjct: 241 ASWGSEDSLSVASDLYGSAFSLYRGRALSIHVSVPQSGLRREEPDLQPQLASEAPRRPAQ 300

Query: 474 KPPTSPSSPPAPVPRVLAAPQNSPVGPGLSISQLAASPRSP 514
            PP+  +  P P PRV    + SP GP    +Q AA+P SP
Sbjct: 301 PPPSKSALLPPPSPRV---GKRSPPGPP---AQPAATPTSP 335


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 40.0 bits (92), Expect = 0.016
 Identities = 38/136 (27%), Positives = 53/136 (38%), Gaps = 7/136 (5%)

Query: 408 PLQGGIQPNPSHCLVYKVPSASMSSEEVKQVESGTLRFQFSLGSEEHLDAPTEPVSGPKV 467
           PLQ    P  S  L    P A+ S +    +    L+  FS      + AP  P + P V
Sbjct: 404 PLQAPPSPPASPPLS---PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 460

Query: 468 --ERRPSRKPPTSPSSPPAPVPRVLAAPQNSPVGPGLSISQLAASPRSPTQHCLARPTSQ 525
                P  + P S ++PP  VP   + P + P+ P  +    A  P +     LA+P  Q
Sbjct: 461 SPSATPPSQAPPSLAAPPLQVPP--SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ 518

Query: 526 LPHGSQASPAQAQEFP 541
            P      P QA   P
Sbjct: 519 APPALATPPLQALPSP 534



 Score = 38.9 bits (89), Expect = 0.036
 Identities = 41/150 (27%), Positives = 55/150 (36%), Gaps = 17/150 (11%)

Query: 407 LPLQGGIQPNPSHCLVYKVPSASMSSEEVKQVESGTLRFQFSLGSEEHLD--APTEPVSG 464
           LPL       P        P A+  S+    + S TL+   S      L   A   P + 
Sbjct: 338 LPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP 397

Query: 465 PKVERRPSRKPPTSPSSPP-----APVPR--------VLAAPQNSPVGPGLSISQLAASP 511
           P +   P + PP+ P+SPP      P P+        +L AP + P  P   +    + P
Sbjct: 398 PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP--PVQAPFSPP 455

Query: 512 RSPTQHCLARPTSQLPHGSQASPAQAQEFP 541
            SP     A P SQ P    A P Q    P
Sbjct: 456 ASPPVSPSATPPSQAPPSLAAPPLQVPPSP 485



 Score = 37.7 bits (86), Expect = 0.080
 Identities = 50/177 (28%), Positives = 67/177 (37%), Gaps = 20/177 (11%)

Query: 427 SASMSSEEVKQVESGTLRFQFSLG------SEEHLDAPTEPVSGPKVERRPSRKPPTSPS 480
           S S +SE      S   R + S G      +   L +   P+S P      +R  P +P+
Sbjct: 208 SVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPA 267

Query: 481 SPPAPVPRVLAAPQNSPVGPGLSISQLAASPRSPTQHCLARPTSQLPHGSQASPAQAQEF 540
            P  P P+ L A +   V P    +  A  P S +   LA P+      SQA P      
Sbjct: 268 HPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP--LATPSPSAALQSQAPPT----L 321

Query: 541 PLEAGISHLEADLSQTSLVL---ETSIAEQLQELPFTPLHAPIVVGTQTRSSAGQPS 594
           P     S L   L+ T L L     S    LQ LP  P   P    +Q  +S G P+
Sbjct: 322 PATPHSSSLTCQLA-TPLPLAPPSPSAPPSLQTLPSPPATPP----SQATTSLGSPT 373



 Score = 32.3 bits (72), Expect = 3.3
 Identities = 28/80 (35%), Positives = 34/80 (42%), Gaps = 13/80 (16%)

Query: 458 PTEPVSGP-KVERRPSRKPPTSP-SSPPAPVPRVLAAPQ-NSPVGPGLSISQLAASPRSP 514
           P+ P S P +    PS   P SP ++PP   P VLAAP    P  P          P SP
Sbjct: 532 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP----------PASP 581

Query: 515 TQHCLARPTSQLPHGSQASP 534
           T     RP +  P  S + P
Sbjct: 582 TLQAPRRPPTPGPDTSVSGP 601


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 40.0 bits (92), Expect = 0.016
 Identities = 38/136 (27%), Positives = 53/136 (38%), Gaps = 7/136 (5%)

Query: 408 PLQGGIQPNPSHCLVYKVPSASMSSEEVKQVESGTLRFQFSLGSEEHLDAPTEPVSGPKV 467
           PLQ    P  S  L    P A+ S +    +    L+  FS      + AP  P + P V
Sbjct: 365 PLQAPPSPPASPPLS---PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 421

Query: 468 --ERRPSRKPPTSPSSPPAPVPRVLAAPQNSPVGPGLSISQLAASPRSPTQHCLARPTSQ 525
                P  + P S ++PP  VP   + P + P+ P  +    A  P +     LA+P  Q
Sbjct: 422 SPSATPPSQAPPSLAAPPLQVPP--SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ 479

Query: 526 LPHGSQASPAQAQEFP 541
            P      P QA   P
Sbjct: 480 APPALATPPLQALPSP 495



 Score = 38.1 bits (87), Expect = 0.061
 Identities = 37/131 (28%), Positives = 51/131 (38%), Gaps = 17/131 (12%)

Query: 426 PSASMSSEEVKQVESGTLRFQFSLGSEEHLD--APTEPVSGPKVERRPSRKPPTSPSSPP 483
           P A+  S+    + S TL+   S      L   A   P + P +   P + PP+ P+SPP
Sbjct: 318 PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPP 377

Query: 484 -----APVPR--------VLAAPQNSPVGPGLSISQLAASPRSPTQHCLARPTSQLPHGS 530
                 P P+        +L AP + P  P   +    + P SP     A P SQ P   
Sbjct: 378 LSPLATPSPQAPNALAVHLLQAPFSPPPSP--PVQAPFSPPASPPVSPSATPPSQAPPSL 435

Query: 531 QASPAQAQEFP 541
            A P Q    P
Sbjct: 436 AAPPLQVPPSP 446



 Score = 36.2 bits (82), Expect = 0.23
 Identities = 42/159 (26%), Positives = 61/159 (38%), Gaps = 10/159 (6%)

Query: 427 SASMSSEEVKQVESGTLRFQFSLG------SEEHLDAPTEPVSGPKVERRPSRKPPTSPS 480
           S S +SE      S   R + S G      +   L +   P+S P      +R  P +P+
Sbjct: 199 SVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPA 258

Query: 481 SPPAPVPRVLAAPQNSPVGPGLSISQLAASPRSPTQHCLARPTSQLPHGSQASPAQAQEF 540
            P  P P+ L A +   V P    +  A  P S +   LA P+   P  S ++P   Q  
Sbjct: 259 HPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP--LATPSPSAP-PSPSAPPSLQTL 315

Query: 541 PLEAGISHLEADLSQTSLVLETSIAEQLQELPFTPLHAP 579
           P        +A  S  S  L+ +    L   P +PL  P
Sbjct: 316 PSPPATPPSQATTSLGSPTLQAT-HSFLPSPPLSPLATP 353



 Score = 32.3 bits (72), Expect = 3.3
 Identities = 28/80 (35%), Positives = 34/80 (42%), Gaps = 13/80 (16%)

Query: 458 PTEPVSGP-KVERRPSRKPPTSP-SSPPAPVPRVLAAPQ-NSPVGPGLSISQLAASPRSP 514
           P+ P S P +    PS   P SP ++PP   P VLAAP    P  P          P SP
Sbjct: 493 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP----------PASP 542

Query: 515 TQHCLARPTSQLPHGSQASP 534
           T     RP +  P  S + P
Sbjct: 543 TLQAPRRPPTPGPDTSVSGP 562


>gi|54860105 nadrin isoform 2 [Homo sapiens]
          Length = 803

 Score = 40.0 bits (92), Expect = 0.016
 Identities = 39/143 (27%), Positives = 55/143 (38%), Gaps = 21/143 (14%)

Query: 415 PNPSHCLVYKVPSASMSSEEV----KQVESGTLRFQFSLGSEEHLDAPTEPVSGPKVERR 470
           P P   +   VP+   ++ ++     Q ++     Q S+G   +   P+     P   RR
Sbjct: 499 PKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPS-----PHTLRR 553

Query: 471 PSRKP---PTSPSSPPAPVPRVLAAPQNSPVGPGLSISQLAASPRSPTQHCLARP----- 522
             +KP   P  P +PP   P   ++   S   P LS      SP  PTQH    P     
Sbjct: 554 AVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSA 613

Query: 523 TSQLP----HGSQASPAQAQEFP 541
            SQL     + S  SP QA   P
Sbjct: 614 PSQLSAPRRYSSSLSPIQAPNHP 636


>gi|111955326 MLX interacting protein [Homo sapiens]
          Length = 919

 Score = 40.0 bits (92), Expect = 0.016
 Identities = 21/62 (33%), Positives = 31/62 (50%), Gaps = 4/62 (6%)

Query: 480 SSPPAPVPRVLAAPQNSPVGPGLSISQLAASPRSPTQHCLARPTSQLPHGSQASPAQAQE 539
           SSPPAPV R+  +    P+G G  +     SP    Q  +  P+   P+  QASP  +++
Sbjct: 639 SSPPAPVSRLFPSTAQDPLGKGEQVPLHGGSP----QVTVTGPSRDCPNSGQASPCASEQ 694

Query: 540 FP 541
            P
Sbjct: 695 SP 696


>gi|194578898 hypothetical protein LOC100170841 [Homo sapiens]
          Length = 379

 Score = 40.0 bits (92), Expect = 0.016
 Identities = 30/91 (32%), Positives = 34/91 (37%), Gaps = 10/91 (10%)

Query: 457 APTEPVSGPKVERRPSRKPPTSPSSPPAPVPRVLAAPQNSPVGPGLSISQLAASPRSPTQ 516
           AP  P  G + +R P+  PP  PSS P   P   A     P GPG      A  P  P Q
Sbjct: 156 APPRPAPGLEPQRGPAASPPQEPSSRPPSPP---AGLSTEPAGPG-----TAPRPFLPGQ 207

Query: 517 --HCLARPTSQLPHGSQASPAQAQEFPLEAG 545
                  P    P    ASP+ A   P   G
Sbjct: 208 PAEVDGNPPPAAPEAPAASPSTASPAPAAPG 238


>gi|236459851 ubinuclein 2 [Homo sapiens]
          Length = 1347

 Score = 39.3 bits (90), Expect = 0.027
 Identities = 64/246 (26%), Positives = 94/246 (38%), Gaps = 54/246 (21%)

Query: 317  SASFSRKVVSSSKTSSGSQALVLRSRLRLPEMVGHPAFAVIFQLEYVFSSPAGVDGNAAS 376
            S+S   ++ +SS     S+A    S  ++ ++  H A     Q  YV    A +  +  +
Sbjct: 898  SSSSQAQIAASSHALGTSEAQDASSLTQVTKVHQHSAV----QQNYVSPLQATISKSQTN 953

Query: 377  -VTSLSN---LACMHMVRWAVWNPLLEADSGRVTLPLQGGIQPNP------SHCLVYK-V 425
             V  LSN   L+C   +      PL+        LPL     P+P      SH LV + V
Sbjct: 954  PVVKLSNNPQLSCSSSLIKTSDKPLM------YRLPLS---TPSPGNGSQGSHPLVSRTV 1004

Query: 426  PSASMSSEE-----VKQVESGTLRFQFSLGSEEHLDAPTEPVSGPKVERRPSRKPPTSPS 480
            PS + SS       V Q+ +   +  FS+ +   L A  +P + P        KP  SP 
Sbjct: 1005 PSTTTSSNYLAKAMVSQISTQGFKSPFSMAASPKLAASPKPATSP--------KPLPSPK 1056

Query: 481  SPPAPVPRVLAAPQNSPVGPGLSISQLAASPRSPTQHCLARPTSQLP--------HGSQA 532
               +P P + A P         S+S    S  +PT      P+S  P        H S  
Sbjct: 1057 PSASPKPSLSAKP---------SVSTKLISKSNPTPKPTVSPSSSSPNALVAQGSHSSTN 1107

Query: 533  SPAQAQ 538
            SP   Q
Sbjct: 1108 SPVHKQ 1113


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 39.3 bits (90), Expect = 0.027
 Identities = 32/85 (37%), Positives = 40/85 (47%), Gaps = 14/85 (16%)

Query: 461 PVSGPKVERRPS--RKPPTSPSSPPAP-VPRVLAAPQ-NSPVGPGLSISQLAASPRSPTQ 516
           P++ P ++  PS    PP SPS+ P P VP +LAAP    P  P  S+      P SP  
Sbjct: 729 PLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASL------PMSP-- 780

Query: 517 HCLARPTSQLPHGSQASPAQAQEFP 541
             LA+P  Q P      P QA   P
Sbjct: 781 --LAKPPPQAPPALATPPLQALPSP 803



 Score = 37.7 bits (86), Expect = 0.080
 Identities = 54/179 (30%), Positives = 69/179 (38%), Gaps = 19/179 (10%)

Query: 454 HLDAPTEPVSGPKVERRPS---RKPPTSPSS---PPAPVPRVLAAPQNSPVGPGLSISQL 507
           HL+ P  P   P ++  PS     PP +PSS   PP   P  LA+P    + P   +S L
Sbjct: 557 HLETPPCPAPCP-LQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGL-PSPPLSPL 614

Query: 508 AASPRSPTQHCLARPTSQLPHGSQASPAQAQ-EFPLEAGISHLEADLSQTSLVLETSIAE 566
            A+P       LA P  Q P    ASP  +    P     + L   L Q       S   
Sbjct: 615 -ATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV 673

Query: 567 QLQELPFTPLHAPIVVGTQTRSSAGQPSRASMVLLQSSGFPEILDANKQPAEAVSATEP 625
           Q    PF+P  +P V  + T  S   PS A+  L      P        P  + SAT P
Sbjct: 674 Q---APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP------ASPPMSPSATPP 723



 Score = 35.8 bits (81), Expect = 0.30
 Identities = 57/226 (25%), Positives = 80/226 (35%), Gaps = 51/226 (22%)

Query: 457 APTEPVSGPKVERRPS------------------RKPPTSPSSPPAPVPRVLAAP--QNS 496
           AP  P + P ++  PS                  + PP+  + PP  VP  L +P  Q  
Sbjct: 344 APPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAP 403

Query: 497 PVGPGLSISQLAASPRSPTQHCLARPTSQLPHGSQAS------PAQA--QEFPLEAGISH 548
           P    LS  Q   S  SPT        +  P  +QAS      PA       PL+A +S 
Sbjct: 404 PSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSL 463

Query: 549 LEADLSQTSLVLETS-------------IAEQLQELPFTPLHAPIVVGTQTRSSAGQPS- 594
             +   QTSL    S             ++      P  PL + I+   +T+SS   PS 
Sbjct: 464 PASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL 523

Query: 595 ---RASMVLLQSSGFPEILDANKQPAEAVSATEPVTFNPQKEESDC 637
               AS+        P +      P    +A+ P+T  P  E   C
Sbjct: 524 QTPPASLTTPPLENLPSL-----APPPLQTASAPLT-TPHLETPPC 563



 Score = 34.3 bits (77), Expect = 0.88
 Identities = 49/186 (26%), Positives = 63/186 (33%), Gaps = 20/186 (10%)

Query: 408 PLQGGIQPNPSHCLVYKVPSASMSSEEVKQVESGTLRFQFSLGSEEHLDAPTEPVSGPKV 467
           PLQ    P  S  L    P A+ S +    +    L+  FS      + AP  P + P V
Sbjct: 629 PLQAPPSPPASPPLS---PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 685

Query: 468 ERR---PSRKPPT----------SPSSPPAPVPRVLAAPQNSPVGPGLSISQLAASPRSP 514
                 PS+ PP+          SP + P   P     PQ  P      +    + P SP
Sbjct: 686 SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP 745

Query: 515 TQHCLARPTSQLPHGSQASPAQAQEF-PLEAGISHLEADLSQTSLVLETSIAEQLQELPF 573
                A P  ++P    A P Q     P    +S L     Q    L T     LQ LP 
Sbjct: 746 PMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALAT---PPLQALPS 802

Query: 574 TPLHAP 579
            P   P
Sbjct: 803 PPASFP 808



 Score = 33.9 bits (76), Expect = 1.1
 Identities = 32/111 (28%), Positives = 41/111 (36%), Gaps = 14/111 (12%)

Query: 465 PKVERRPSRKPPTSPSSPPAPVPRVLAAP--------QNSPVGPGLSISQLAASPRSPTQ 516
           P  +   +  P T P SPP   P  LA P        Q  P  P    SQ   S  +P  
Sbjct: 318 PPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPM 377

Query: 517 HC----LARPTSQLPHGSQASPAQAQEFPLEAGISHLEADLSQTSLVLETS 563
                    P  Q+PH   +   QA   PL   +S L+A  S  S  L+ +
Sbjct: 378 QAPPSLQTIPPIQVPHSLTSPSLQAPPSPL--ALSSLQATTSLGSPTLQAT 426



 Score = 32.3 bits (72), Expect = 3.3
 Identities = 28/80 (35%), Positives = 34/80 (42%), Gaps = 13/80 (16%)

Query: 458 PTEPVSGP-KVERRPSRKPPTSP-SSPPAPVPRVLAAPQ-NSPVGPGLSISQLAASPRSP 514
           P+ P S P +    PS   P SP ++PP   P VLAAP    P  P          P SP
Sbjct: 801 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP----------PASP 850

Query: 515 TQHCLARPTSQLPHGSQASP 534
           T     RP +  P  S + P
Sbjct: 851 TLQAPRRPPTPGPDTSVSGP 870



 Score = 32.0 bits (71), Expect = 4.4
 Identities = 32/114 (28%), Positives = 47/114 (41%), Gaps = 11/114 (9%)

Query: 427 SASMSSEEVKQVESGTLRFQFSLG------SEEHLDAPTEPVSGPKVERRPSRKPPTSPS 480
           S S +SE      S   R + S G      +   L +   P+S P      +R  P +P+
Sbjct: 208 SVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPA 267

Query: 481 SPPAPVPRVLAAPQNSPVGPGLSISQLAASPRSPTQHCLARPTSQLPHGSQASP 534
            P  P P+ L A +   V P    +  A  P S +   LA P+   P G++A P
Sbjct: 268 HPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP--LATPS---PSGTKARP 316


>gi|197313748 SET domain containing 2 [Homo sapiens]
          Length = 2564

 Score = 39.3 bits (90), Expect = 0.027
 Identities = 46/175 (26%), Positives = 70/175 (40%), Gaps = 18/175 (10%)

Query: 407 LPLQGGIQPNPSHCLVYKVPSASMSSEEVKQVESGTLRFQFSL--GSEEHLDAPTEPVSG 464
           +PLQ    P     +   + +A  SS    +VE G + F+  L   +   L A T  V+ 
Sbjct: 106 VPLQVDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLHVTSRPLLATTTAVAS 165

Query: 465 PKVERRP-------SRKPPTSPSSPPAPVPRVLAAPQNSPVGPGLSISQLAASPRSPTQH 517
           P     P       S    + PSSPP P P   A   +SP      +++  A P +P   
Sbjct: 166 PPTHAAPLPAVIAESTTVDSPPSSPPPPPPPAQATTLSSPA----PVTEPVALPHTPITV 221

Query: 518 CLARPTSQLPHGSQASPAQAQEFPLEAGISHLEADLSQTSL--VLETSIAEQLQE 570
            +A P   +P     +    +E P+      LEAD  Q ++   LE  + + L E
Sbjct: 222 LMAAP---VPLPVDVAVRSLKEPPIIIVPESLEADTKQDTISNSLEEHVTQILNE 273


>gi|5802980 activating transcription factor 7 isoform 2 [Homo
           sapiens]
          Length = 483

 Score = 38.9 bits (89), Expect = 0.036
 Identities = 43/159 (27%), Positives = 66/159 (41%), Gaps = 28/159 (17%)

Query: 431 SSEEVKQVESGTLRFQFSLGSEEHLDAPTE-PVSGPKVERRPSRKPPTSPSSPP------ 483
           + E+ K+  +G L    SL S   +    E PV   +V+  P   P +SP SPP      
Sbjct: 82  ADEDEKKAAAGPL--DMSLPSTPDIKIKEEEPV---EVDSSPPDSPASSPCSPPLKEKEV 136

Query: 484 APVPRVLAAPQNSPVGPGLSISQLAASPRSPTQHCLARPTSQLPHGSQASPAQAQEFPLE 543
            P P +++ P  + V PG     L   P  PT   L  PTS +   +QA P+  Q     
Sbjct: 137 TPKPVLISTPTPTIVRPGSLPLHLGYDPLHPT---LPSPTSVI---TQAPPSNRQ----- 185

Query: 544 AGISHLEADLSQTSLVLETSIAEQLQELPFTPLHAPIVV 582
                + +      LV+  +  + +  LP  P+  P V+
Sbjct: 186 -----MGSPTGSLPLVMHLANGQTMPVLPGPPVQMPSVI 219


>gi|166706868 synaptopodin 2-like isoform a [Homo sapiens]
          Length = 977

 Score = 38.9 bits (89), Expect = 0.036
 Identities = 47/178 (26%), Positives = 70/178 (39%), Gaps = 32/178 (17%)

Query: 373 NAASVTSLSNLACMHMVRWAVWNPLLEADSGRVTLPLQ-----GGIQPNPSHCLVYKVPS 427
           N  S T+LS+ + M          L++A   ++ L +Q     G +Q    H L    P 
Sbjct: 57  NGVSCTNLSHASAMS---------LIDASGNQLVLTVQRLADEGPVQSPSPHELQVLSPL 107

Query: 428 ASMSSEEV-----KQVESGTLRFQFSLGSEEHLDAPTEPVSGPKVE---RRPSRKPPTSP 479
           + +S E       + ++ G+LR      SE +         GP  +   RRP R+ PT P
Sbjct: 108 SPLSPEPPGAPVPQPLQPGSLRSPPD--SEAYYGETDSDADGPATQEKPRRPRRRGPTRP 165

Query: 480 SSPPAPVPRVL-----AAPQNSPVGPGLSISQLAASPRSPTQHCLARPTSQ---LPHG 529
           + P AP   V      A P  +  GP        +SP       L  P ++   LPHG
Sbjct: 166 TPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPPAEALLLPHG 223


>gi|46276868 hypothetical protein LOC9710 [Homo sapiens]
          Length = 1070

 Score = 38.9 bits (89), Expect = 0.036
 Identities = 40/133 (30%), Positives = 54/133 (40%), Gaps = 25/133 (18%)

Query: 468 ERRPSRKPPTSPSSPPAPVPRVLAAPQNSPV--GPGLSISQLAASPRSPT----QHCLAR 521
           E++     P  PS P  P PR   A  ++P+   PGL+  Q +   + P     QH L  
Sbjct: 681 EQKAGAMQPQQPSLPVPPPPRAPQAGAHTPLTPQPGLAPQQQSPKQQQPQVQYYQHLLQP 740

Query: 522 PTSQLP-----------HGSQASPAQAQEFPLE-----AGISHLEADLSQTSLV---LET 562
              Q P           HGS   PAQA    L       GIS L +DL    LV   ++ 
Sbjct: 741 IGPQQPPPQPRAPGKWVHGSSQQPAQAVGAGLSPLGQWPGISDLSSDLYSLGLVSSYMDN 800

Query: 563 SIAEQLQELPFTP 575
            ++E L + P  P
Sbjct: 801 VMSEVLGQKPQGP 813


>gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo
           sapiens]
          Length = 834

 Score = 38.5 bits (88), Expect = 0.047
 Identities = 57/214 (26%), Positives = 77/214 (35%), Gaps = 40/214 (18%)

Query: 460 EPVSGPKVERRPSRKPP---------TSPSSPPAPVPR--------VLAAPQNS----PV 498
           E  + P+    PS  P          TSPSSP AP           +  AP  S    P 
Sbjct: 269 ETTTKPQATSAPSPAPKQSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPT 328

Query: 499 GPGLSISQLAASPRS-PTQHCLARPTSQLPHGSQASPAQAQEFPLEAGI---SHLEADLS 554
            PG S+S  A S  S PT      PT Q    S   PA     PL A     +   A   
Sbjct: 329 PPGPSVSATAPSSSSLPTTTSTTAPTFQPVFSSMGPPASV---PLPAPFFKQTTTPATAP 385

Query: 555 QTSLVLETSIAEQLQELPFTPLHAPIVVGTQTRSSAGQPSRASMVLLQSSGFPEILDANK 614
            T+  L T +A        T   API   + +  SA +P+    +   SS        + 
Sbjct: 386 TTTAPLFTGLASA------TSAVAPITSASPSTDSASKPAFGFGINSVSSS-----SVST 434

Query: 615 QPAEAVSATEPVTFN-PQKEESDCLQSNEMVLQF 647
             + A +A++P  F  PQ   +    +   + QF
Sbjct: 435 TTSTATAASQPFLFGAPQASAASFTPAMGSIFQF 468


>gi|149944516 tet oncogene family member 3 [Homo sapiens]
          Length = 1660

 Score = 38.5 bits (88), Expect = 0.047
 Identities = 35/120 (29%), Positives = 49/120 (40%), Gaps = 8/120 (6%)

Query: 415 PNPSHCLVYKVPSASMSSEEVKQVESGT---LRFQFSLGSEEHLD----APTEPVSGPKV 467
           P PS  L  + P+ S   +  ++ ++     L  + SL  E+  D    AP+EP S P  
Sbjct: 366 PAPSPVLQREAPTPSSEPDTHQKAQTALQQHLHHKRSLFLEQVHDTSFPAPSEP-SAPGW 424

Query: 468 ERRPSRKPPTSPSSPPAPVPRVLAAPQNSPVGPGLSISQLAASPRSPTQHCLARPTSQLP 527
              PS   P  P  PP    + L  P   PVG   +   +  S R P Q   +RP    P
Sbjct: 425 WPPPSSPVPRLPDRPPKEKKKKLPTPAGGPVGTEKAAPGIKPSVRKPIQIKKSRPREAQP 484


>gi|56549696 E1A binding protein p400 [Homo sapiens]
          Length = 3122

 Score = 38.5 bits (88), Expect = 0.047
 Identities = 33/136 (24%), Positives = 56/136 (41%), Gaps = 9/136 (6%)

Query: 397  LLEADSGRVTLPLQ-----GGIQPNPSHCLVYKVPSASMSSEEVKQVESGTLRFQFSLGS 451
            L++  +G+ + P++        Q NP H  V    S     + +  ++  +LR +  +  
Sbjct: 2430 LMKMTAGKRSPPIKPLLGMNPFQKNPKHASVL-AESGINYDKPLPPIQVASLRAE-RIAK 2487

Query: 452  EEHLDAPTEPVSGPKVERRP--SRKPPTSPSSPPAPVPRVLAAPQNSPVGPGLSISQLAA 509
            E+   A  +    P V + P    +PP  P  PP P+P+  AA    P GP     Q   
Sbjct: 2488 EKKALADQQKAQQPAVAQPPPPQPQPPPPPQQPPPPLPQPQAAGSQPPAGPPAVQPQPQP 2547

Query: 510  SPRSPTQHCLARPTSQ 525
             P++  Q   A   +Q
Sbjct: 2548 QPQTQPQPVQAPAKAQ 2563


>gi|194239640 activating transcription factor 7 isoform 1 [Homo
           sapiens]
          Length = 494

 Score = 38.5 bits (88), Expect = 0.047
 Identities = 36/129 (27%), Positives = 54/129 (41%), Gaps = 25/129 (19%)

Query: 460 EPVSGPKVERRPSRKPPTSPSSPP------APVPRVLAAPQNSPVGPGLSISQLAASPRS 513
           EPV   +V+  P   P +SP SPP       P P +++ P  + V PG     L   P  
Sbjct: 121 EPV---EVDSSPPDSPASSPCSPPLKEKEVTPKPVLISTPTPTIVRPGSLPLHLGYDPLH 177

Query: 514 PTQHCLARPTSQLPHGSQASPAQAQEFPLEAGISHLEADLSQTSLVLETSIAEQLQELPF 573
           PT   L  PTS +   +QA P+  Q          + +      LV+  +  + +  LP 
Sbjct: 178 PT---LPSPTSVI---TQAPPSNRQ----------MGSPTGSLPLVMHLANGQTMPVLPG 221

Query: 574 TPLHAPIVV 582
            P+  P V+
Sbjct: 222 PPVQMPSVI 230


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
           sapiens]
          Length = 1560

 Score = 38.5 bits (88), Expect = 0.047
 Identities = 45/148 (30%), Positives = 56/148 (37%), Gaps = 15/148 (10%)

Query: 440 SGTLRFQFSLGSEEHLDAP------TEPVSGPKVERRPSRKPPTSPSSPPAPVPRV--LA 491
           S +L  Q  LG   HL +P      + P S P+   RP  +PP  P  PP   P +  + 
Sbjct: 776 SPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIF 835

Query: 492 APQNSPVGPGLSISQLAASPRSPTQHCLARPTSQLPHGSQASPAQAQEFPLEAGISHLEA 551
             QN  +G     S  A +   P Q  L RP SQ P G    P         +  S   A
Sbjct: 836 VIQNQ-LGVPPPASNPAPTAPGPPQPPL-RPQSQPPEG----PLPPAPHLPPSSTSSAVA 889

Query: 552 DLSQTSLVLETSIAEQLQELPFTPLHAP 579
             S+TS  L        Q L F P   P
Sbjct: 890 SSSETSSRLPAPTPSDFQ-LQFPPSQGP 916



 Score = 35.4 bits (80), Expect = 0.40
 Identities = 43/152 (28%), Positives = 64/152 (42%), Gaps = 22/152 (14%)

Query: 412 GIQPNPSHCLVYKVPSASMSS---EEVKQVESGTLRFQFSLGSE-EHLDAPTEP-VSGPK 466
           G+  +P   ++ + PSA+ ++   ++  Q+     R Q  L +E  HL  P    VS P 
Sbjct: 669 GLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPP 728

Query: 467 VERRPSRKPPTS------PSSP-----PAPVPRVLAAPQNSPVGPGLSIS-----QLAAS 510
             + P+   P +      P +P     PAP P++ AA      GP  S S      L  S
Sbjct: 729 PAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDS 788

Query: 511 PRSPTQHCLARPTSQLPHGSQASPAQAQEFPL 542
           P  P+ H   RP S+ P   Q+      E PL
Sbjct: 789 PHLPSPH-PTRPPSRPPSRPQSVSRPPSEPPL 819



 Score = 33.9 bits (76), Expect = 1.1
 Identities = 30/127 (23%), Positives = 47/127 (37%), Gaps = 9/127 (7%)

Query: 476 PTSPSSPPAPVPRVLAAPQNSPVGPGLSISQLAASPRSPTQHCLARPTSQLPHGSQASPA 535
           P +   P AP P+  A PQ +   P   ++       SP +  L +P S  P       +
Sbjct: 642 PQAQQPPQAPTPQAAAPPQATTPQPSPGLAS------SPEKIVLGQPPSATPTAILTQDS 695

Query: 536 QAQEFPLEAGISHLEAD---LSQTSLVLETSIAEQLQELPFTPLHAPIVVGTQTRSSAGQ 592
                P E     L A+   LS  + V+ ++        P TP+     +G Q   S   
Sbjct: 696 LQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQAS 755

Query: 593 PSRASMV 599
           P+ A  +
Sbjct: 756 PAPAPQI 762



 Score = 31.2 bits (69), Expect = 7.5
 Identities = 56/242 (23%), Positives = 84/242 (34%), Gaps = 38/242 (15%)

Query: 413 IQPNPSHCLVYKV------PSASMSSEEVKQVESGTLRFQ--------FSLGSEEHLDAP 458
           IQP P+  L  K+      P A   +    Q E G L  Q        F    +   +  
Sbjct: 351 IQPKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVV 410

Query: 459 TEPVSGPKVERRPSRKPP--TSPSSPPAPVPRVLAAPQNSPVGPGLSISQLAASPRSPTQ 516
                 P ++    ++PP  T+ ++PP P P  L+ P +      + +    +S   P Q
Sbjct: 411 LSGFPAPALQANVFKQPPATTTGAAPPQP-PGALSKPMS------VHLLNQGSSIVIPAQ 463

Query: 517 HCL---------ARPTSQLPHGSQASPAQAQEFPLEAGISHLEADLSQTSLVLETSIAEQ 567
           H L           P  QLP    A PA      L A   H    L    ++   ++A  
Sbjct: 464 HMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGP 523

Query: 568 LQELPFTPLHA---PIVVGTQTRSSAGQPSRASMVLLQSSGFPEILDANKQPAEAVSATE 624
           L   P    H+      + +      GQP+   M +  ++G    L    QPA A  A  
Sbjct: 524 LSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAG---SLPTQSQPAPAGPAAT 580

Query: 625 PV 626
            V
Sbjct: 581 TV 582


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 38.1 bits (87), Expect = 0.061
 Identities = 86/396 (21%), Positives = 146/396 (36%), Gaps = 66/396 (16%)

Query: 166  LLQDPAEQNRHMTLIENCSLQYTLKPHPALEPAFHLLPENLLVS--GLQQI----PGLLP 219
            LL+D A  + H    E        K   +   + HLL E L ++  G++ +    P L  
Sbjct: 730  LLEDQAPAHFHRNFPEQVFQDLQRKSPESEILSLHLLVEELRLNPDGVETVNDTKPELNV 789

Query: 220  AHGESGDALRK---------PRLQKPITGHLDDLFFTLYPSLEKFEEELLELHVQDHFQE 270
            A  E G+  R+         P  Q    G+ + +     P L++         V+D    
Sbjct: 790  ASSEGGEMERRDSDSFLNIFPEKQVTKAGNTEPVLEEWIPVLQRPSRTAAVPTVKDALDA 849

Query: 271  GC-GPLDGGALEILERRLRVGVHNGLGFVQRPQVVVLVPEMDVALTRSASFSRKVVSSSK 329
                P +G ++        V    G   V     +V  P  D+ +    S   + V+++ 
Sbjct: 850  ALPSPEEGTSIAA------VPAPEGTAVVA---ALVPFPHEDILVASIVSLEEEDVTAAA 900

Query: 330  TSSGSQALVLRSRLRLPEMVGHPAFAVIFQLEYVFSSPAGVDGNAASVTSLSNLACMHMV 389
             S+  +A V    + +PE  G  A A +       SSP       A+  +   ++ +   
Sbjct: 901  VSAPERATVPAVTVSVPE--GTAAVAAV-------SSPEETAPAVAAAITQEGMSAV--- 948

Query: 390  RWAVWNPLLEADSGRVTLPLQGGIQPNPSHCLVYKVPSASMSSEEVKQVESGTLRFQFSL 449
              A ++P   A +  V +  + G    P        P+ ++ + E  + ++  +R    +
Sbjct: 949  --AGFSPEWAALAITVPITEEDGTPEGPV------TPATTVHAPE--EPDTAAVR----V 994

Query: 450  GSEEHLDAPTEPVSGPKVERRPSRKPPT--SPSSPPAPVPRVLAAPQNSPVGPGLSISQL 507
             + E   +P   V  P+    P+   PT   P+SP A VP     P   P  P  ++   
Sbjct: 995  STPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP-----PPEEPTSPAAAVP-- 1047

Query: 508  AASPRSPTQHCLARPTSQLPHGSQASPAQAQEFPLE 543
              +P  PT    A PT + P     SPA A   P E
Sbjct: 1048 --TPEEPTSPAAAVPTPEEP----TSPAAAVPTPEE 1077


>gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens]
          Length = 1243

 Score = 38.1 bits (87), Expect = 0.061
 Identities = 46/167 (27%), Positives = 69/167 (41%), Gaps = 21/167 (12%)

Query: 472  SRKPPTSPSSPPAPVPRVLAAPQNSPVGPGLSISQLAASPRSPTQHCLARPTSQLPHGSQ 531
            S  P     SPPAP   + + P   PV PG           SP+ H     T+++   S+
Sbjct: 943  SPSPGLLSQSPPAPPSPLPSLPLPPPVAPG--------GQESPSPH-----TAEVE--SE 987

Query: 532  ASPAQAQEFPLEAGISHL--EADLSQTSLVLETSIAEQLQELPFTPLHAPIVVGTQTRSS 589
            ASP  A+  P EA ++ +  E           TS  E  + LP  P  +P + G+   S+
Sbjct: 988  ASPPPARPLPGEARLAPISEEGKPQLVGRFQVTSSKEPAEPLPLQPT-SPTLSGSPKPST 1046

Query: 590  AGQPSRASMVLLQSSGFPEILDANKQPAEAVSATEPVTFNPQKEESD 636
                S +S     + G PE  +A    AE+  A E +    ++E  D
Sbjct: 1047 PQLTSESSDTEDSAGGGPETREA---LAESDRAAEGLGAGVEEEGDD 1090



 Score = 30.8 bits (68), Expect = 9.7
 Identities = 29/116 (25%), Positives = 42/116 (36%), Gaps = 17/116 (14%)

Query: 625 PVTFNPQKEESDCLQSNEMVLQFLAFSRVAQDCRGTSWPKTVYFTFQFYRFPPATTPRLQ 684
           P  F P+ EE +  Q    + +  ++S    DC    +  +  F         A+ P LQ
Sbjct: 551 PSVFPPEPEEPEADQHQPFLFRHASYSSTTSDCETDGYLSSSGFL-------DASDPALQ 603

Query: 685 LVQLDEAGQPSSGALTHILVP------VSRDGTFDAGSPGFQLRYMVGPGFLKPGE 734
                  G PSS A +H+ +P      + R G     SPG         G    GE
Sbjct: 604 ----PPGGVPSSLAESHLCLPSAFALSIPRSGPGSDFSPGDSYASDAASGLSDVGE 655


>gi|27477095 nuclear receptor binding SET domain protein 1 isoform a
            [Homo sapiens]
          Length = 2427

 Score = 38.1 bits (87), Expect = 0.061
 Identities = 55/215 (25%), Positives = 95/215 (44%), Gaps = 40/215 (18%)

Query: 433  EEVKQVESGTLRFQFSLGSEEHLDAPTEPVSGPKVERRPSRKPPTSPSSPPAPVPRVLAA 492
            ++V+ +     + Q  + S+  LD P   V+GP+ +      P TSPSS P+    V + 
Sbjct: 2025 DKVRDLAGSGTKSQSLVSSQRPLDRPPA-VAGPRPQLSDKPSPVTSPSSSPS----VRSQ 2079

Query: 493  PQNSPVG---PGLSISQLAASPRSPTQHCLARPTS-QLPHGSQ----ASP-AQAQEFPLE 543
            P   P+G   P L  S  AASPR  +    + PT  +LP   +    +SP  Q  + P +
Sbjct: 2080 PLERPLGTADPRLDKSIGAASPRPQSLEKTSVPTGLRLPPPDRLLITSSPKPQTSDRPTD 2139

Query: 544  AGISHLEADL----SQTSLVLETSIAEQLQELPFTPLHAPIVVGTQTRSSAGQPSRASMV 599
               + L   L       S V++T +A++           P+   TQ++      +RA++V
Sbjct: 2140 KPHASLSQRLPPPEKVLSAVVQTLVAKE-------KALRPVDQNTQSK------NRAALV 2186

Query: 600  LLQSSGFPEILDANKQPAEAVSATEPVTFNPQKEE 634
            +       +++D   +  E  ++   VT  PQ +E
Sbjct: 2187 M-------DLIDLTPRQKERAASPHQVT--PQADE 2212


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,918,370
Number of Sequences: 37866
Number of extensions: 3057898
Number of successful extensions: 15024
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 423
Number of HSP's that attempted gapping in prelim test: 12880
Number of HSP's gapped (non-prelim): 2097
length of query: 1426
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1311
effective length of database: 13,892,928
effective search space: 18213628608
effective search space used: 18213628608
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.