BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo sapiens] (750 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo... 1492 0.0 gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo... 1492 0.0 gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Hom... 843 0.0 gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo... 843 0.0 gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo... 838 0.0 gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Hom... 828 0.0 gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo... 754 0.0 gi|41406089 SRY-box 13 [Homo sapiens] 431 e-120 gi|11967991 SRY-box 17 [Homo sapiens] 112 2e-24 gi|13899269 SRY-box 7 [Homo sapiens] 109 8e-24 gi|4557853 transcription factor SOX9 [Homo sapiens] 109 8e-24 gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens] 106 9e-23 gi|4507161 SRY-box 11 [Homo sapiens] 105 2e-22 gi|4759162 SRY-box 14 [Homo sapiens] 105 2e-22 gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens] 104 3e-22 gi|8924248 SRY-box 18 [Homo sapiens] 103 4e-22 gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens] 103 8e-22 gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens] 102 1e-21 gi|5902108 SRY-box 21 [Homo sapiens] 102 1e-21 gi|28195386 sex-determining region Y-box 2 [Homo sapiens] 101 2e-21 gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens] 100 6e-21 gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens] 99 1e-20 gi|4507225 sex determining region Y [Homo sapiens] 98 2e-20 gi|5902106 SRY-box 15 [Homo sapiens] 98 3e-20 gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo... 82 2e-15 gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Hom... 82 2e-15 gi|112421108 capicua homolog [Homo sapiens] 72 2e-12 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 64 5e-10 gi|195222734 lymphoid enhancer-binding factor 1 isoform 3 [Homo ... 63 9e-10 gi|226371764 transcription factor 7-like 2 isoform 1 [Homo sapiens] 61 4e-09 >gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo sapiens] Length = 750 Score = 1492 bits (3862), Expect = 0.0 Identities = 750/750 (100%), Positives = 750/750 (100%) Query: 1 MSSKRPASPYGEADGEVAMVTSRQKVEEEESDGLPAFHLPLHVSFPNKPHSEEFQPVSLL 60 MSSKRPASPYGEADGEVAMVTSRQKVEEEESDGLPAFHLPLHVSFPNKPHSEEFQPVSLL Sbjct: 1 MSSKRPASPYGEADGEVAMVTSRQKVEEEESDGLPAFHLPLHVSFPNKPHSEEFQPVSLL 60 Query: 61 TQETCGHRTPTSQHNTMEVDGNKVMSSFAPHNSSTSPQKAEEGGRQSGESLSSTALGTPE 120 TQETCGHRTPTSQHNTMEVDGNKVMSSFAPHNSSTSPQKAEEGGRQSGESLSSTALGTPE Sbjct: 61 TQETCGHRTPTSQHNTMEVDGNKVMSSFAPHNSSTSPQKAEEGGRQSGESLSSTALGTPE 120 Query: 121 RRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAMGSGNFGEIKGTPE 180 RRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAMGSGNFGEIKGTPE Sbjct: 121 RRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAMGSGNFGEIKGTPE 180 Query: 181 SLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQIARQQQ 240 SLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQIARQQQ Sbjct: 181 SLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQIARQQQ 240 Query: 241 QLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAAQQGFLLPPGFSYKAGCSDP 300 QLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAAQQGFLLPPGFSYKAGCSDP Sbjct: 241 QLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAAQQGFLLPPGFSYKAGCSDP 300 Query: 301 YPVQLIPTTMAAAAAATPGLGPLQLQQLYAAQLAAMQVSPGGKLPGIPQGNLGAAVSPTS 360 YPVQLIPTTMAAAAAATPGLGPLQLQQLYAAQLAAMQVSPGGKLPGIPQGNLGAAVSPTS Sbjct: 301 YPVQLIPTTMAAAAAATPGLGPLQLQQLYAAQLAAMQVSPGGKLPGIPQGNLGAAVSPTS 360 Query: 361 IHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSDGKSPTSPTSPHMPALRINSGAGPLKASV 420 IHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSDGKSPTSPTSPHMPALRINSGAGPLKASV Sbjct: 361 IHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSDGKSPTSPTSPHMPALRINSGAGPLKASV 420 Query: 421 PAALASPSARVSTIGYLNDHDAVTKAIQEARQMKEQLRREQQVLDGKVAVVNSLGLNNCR 480 PAALASPSARVSTIGYLNDHDAVTKAIQEARQMKEQLRREQQVLDGKVAVVNSLGLNNCR Sbjct: 421 PAALASPSARVSTIGYLNDHDAVTKAIQEARQMKEQLRREQQVLDGKVAVVNSLGLNNCR 480 Query: 481 TEKEKTTLESLTQQLAVKQNEEGKFSHAMMDFNLSGDSDGSAGVSESRIYRESRGRGSNE 540 TEKEKTTLESLTQQLAVKQNEEGKFSHAMMDFNLSGDSDGSAGVSESRIYRESRGRGSNE Sbjct: 481 TEKEKTTLESLTQQLAVKQNEEGKFSHAMMDFNLSGDSDGSAGVSESRIYRESRGRGSNE 540 Query: 541 PHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLS 600 PHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLS Sbjct: 541 PHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLS 600 Query: 601 KQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIATA 660 KQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIATA Sbjct: 601 KQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIATA 660 Query: 661 GVVYPGAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEIQAEDING 720 GVVYPGAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEIQAEDING Sbjct: 661 GVVYPGAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEIQAEDING 720 Query: 721 EIYDEYDEEEDDPDVDYGSDSENHIAGQAN 750 EIYDEYDEEEDDPDVDYGSDSENHIAGQAN Sbjct: 721 EIYDEYDEEEDDPDVDYGSDSENHIAGQAN 750 >gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo sapiens] Length = 763 Score = 1492 bits (3862), Expect = 0.0 Identities = 750/750 (100%), Positives = 750/750 (100%) Query: 1 MSSKRPASPYGEADGEVAMVTSRQKVEEEESDGLPAFHLPLHVSFPNKPHSEEFQPVSLL 60 MSSKRPASPYGEADGEVAMVTSRQKVEEEESDGLPAFHLPLHVSFPNKPHSEEFQPVSLL Sbjct: 14 MSSKRPASPYGEADGEVAMVTSRQKVEEEESDGLPAFHLPLHVSFPNKPHSEEFQPVSLL 73 Query: 61 TQETCGHRTPTSQHNTMEVDGNKVMSSFAPHNSSTSPQKAEEGGRQSGESLSSTALGTPE 120 TQETCGHRTPTSQHNTMEVDGNKVMSSFAPHNSSTSPQKAEEGGRQSGESLSSTALGTPE Sbjct: 74 TQETCGHRTPTSQHNTMEVDGNKVMSSFAPHNSSTSPQKAEEGGRQSGESLSSTALGTPE 133 Query: 121 RRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAMGSGNFGEIKGTPE 180 RRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAMGSGNFGEIKGTPE Sbjct: 134 RRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAMGSGNFGEIKGTPE 193 Query: 181 SLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQIARQQQ 240 SLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQIARQQQ Sbjct: 194 SLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQIARQQQ 253 Query: 241 QLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAAQQGFLLPPGFSYKAGCSDP 300 QLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAAQQGFLLPPGFSYKAGCSDP Sbjct: 254 QLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAAQQGFLLPPGFSYKAGCSDP 313 Query: 301 YPVQLIPTTMAAAAAATPGLGPLQLQQLYAAQLAAMQVSPGGKLPGIPQGNLGAAVSPTS 360 YPVQLIPTTMAAAAAATPGLGPLQLQQLYAAQLAAMQVSPGGKLPGIPQGNLGAAVSPTS Sbjct: 314 YPVQLIPTTMAAAAAATPGLGPLQLQQLYAAQLAAMQVSPGGKLPGIPQGNLGAAVSPTS 373 Query: 361 IHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSDGKSPTSPTSPHMPALRINSGAGPLKASV 420 IHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSDGKSPTSPTSPHMPALRINSGAGPLKASV Sbjct: 374 IHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSDGKSPTSPTSPHMPALRINSGAGPLKASV 433 Query: 421 PAALASPSARVSTIGYLNDHDAVTKAIQEARQMKEQLRREQQVLDGKVAVVNSLGLNNCR 480 PAALASPSARVSTIGYLNDHDAVTKAIQEARQMKEQLRREQQVLDGKVAVVNSLGLNNCR Sbjct: 434 PAALASPSARVSTIGYLNDHDAVTKAIQEARQMKEQLRREQQVLDGKVAVVNSLGLNNCR 493 Query: 481 TEKEKTTLESLTQQLAVKQNEEGKFSHAMMDFNLSGDSDGSAGVSESRIYRESRGRGSNE 540 TEKEKTTLESLTQQLAVKQNEEGKFSHAMMDFNLSGDSDGSAGVSESRIYRESRGRGSNE Sbjct: 494 TEKEKTTLESLTQQLAVKQNEEGKFSHAMMDFNLSGDSDGSAGVSESRIYRESRGRGSNE 553 Query: 541 PHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLS 600 PHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLS Sbjct: 554 PHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLS 613 Query: 601 KQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIATA 660 KQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIATA Sbjct: 614 KQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIATA 673 Query: 661 GVVYPGAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEIQAEDING 720 GVVYPGAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEIQAEDING Sbjct: 674 GVVYPGAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEIQAEDING 733 Query: 721 EIYDEYDEEEDDPDVDYGSDSENHIAGQAN 750 EIYDEYDEEEDDPDVDYGSDSENHIAGQAN Sbjct: 734 EIYDEYDEEEDDPDVDYGSDSENHIAGQAN 763 >gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Homo sapiens] Length = 801 Score = 843 bits (2179), Expect = 0.0 Identities = 481/811 (59%), Positives = 571/811 (70%), Gaps = 71/811 (8%) Query: 1 MSSKRPASPYG-EADGEVAM---VTSRQKVEEEESDGLPAFHLPLHVSFPNKPHSEEFQP 56 MSSK+ SP+ ADGE AM +TSR+K EE SD A HLPLH NKPHSEE Sbjct: 1 MSSKQATSPFACAADGEDAMTQDLTSREK--EEGSDQHVASHLPLHPIMHNKPHSEELPT 58 Query: 57 VSLLTQETCGHRTPTSQHNTMEVDGNKVMSSFAPHNSSTSPQKAEEGGRQSGESLSSTAL 116 + Q+ + S ME + NK+ S ++ N+STSP K +EG R E ++S Sbjct: 59 LVSTIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDR-EIMTSVTF 117 Query: 117 GTPERRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAMGSGNF-GEI 175 GTPERRKGSLADVVDTLKQ+K+EE+ + E E++ +EKLLSKDWK+K+ + + GEI Sbjct: 118 GTPERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEI 177 Query: 176 KGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQI 235 KGTPESLAEKERQL MI QL SLREQLLAAHDEQKKLAASQIEKQRQQM+LA+QQQEQI Sbjct: 178 KGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQI 237 Query: 236 ARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAA--QQGFLLPPGFSY 293 ARQQQQLLQQQHKINLLQQQIQVQG +PPLMIP+FP DQRTLAAAA QQGFL PPG +Y Sbjct: 238 ARQQQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITY 297 Query: 294 KAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQQLYAAQLAAMQVSPGGKLPGIPQG-NL 352 K G D YPVQ IP+TMAAAAA+ GL PLQLQQLYAAQLA+MQVSPG K+P PQ N Sbjct: 298 KPG--DNYPVQFIPSTMAAAAAS--GLSPLQLQQLYAAQLASMQVSPGAKMPSTPQPPNT 353 Query: 353 GAAVSPTSIHTDKSTNSPPPKSKDEVA-QPLNLSAKPKTSDG-KSPTSPTSPHMPALRIN 410 VSPT I +K SP + KDE A QPLNLS++PKT++ KSPTSPT PA + + Sbjct: 354 AGTVSPTGIKNEKRGTSPVTQVKDEAAAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTS 413 Query: 411 SGAGPLKASVPAALASPSARVSTIG-----------------------YLNDHDAVTKAI 447 P K+S+P+ + R S++G D D V KAI Sbjct: 414 PVNLPNKSSIPSPIGGSLGRGSSLGKWKSQHQEETYELDILSSLNSPALFGDQDTVMKAI 473 Query: 448 QEARQMKEQLRREQQV-----LDGKVAVVNSLGLNNCRTEKEKTTLESLTQQLAVKQNEE 502 QEAR+M+EQ++REQQ +DGK++ +N++GLN+CR EKE+T E+L QL K NE+ Sbjct: 474 QEARKMREQIQREQQQQQPHGVDGKLSSINNMGLNSCRNEKERTRFENLGPQLTGKSNED 533 Query: 503 GKFSHAMMDFNLSGDSDGS--------------------AGVSESRIYRESRGRGSNEPH 542 GK ++D D++GS A V+E+R+YR++RGR S+EPH Sbjct: 534 GKLGPGVIDLTRPEDAEGSKAMNGSAAKLQQYYCWPTGGATVAEARVYRDARGRASSEPH 593 Query: 543 IKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQ 602 IKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWK+M+N EKQPYYEEQARLSK Sbjct: 594 IKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKI 653 Query: 603 HLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIAT-AG 661 HLEKYP+YKYKPRPKRTC+VDGKKLRIGEYK +MR+RRQEMRQ+F VGQQ QIPI T G Sbjct: 654 HLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGTG 713 Query: 662 VVYPGAIAMA-GMPSPHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEIQAEDING 720 VVYPGAI MA PSP + S+ SS S+SPEP +PVIQSTYG+K + + E ING Sbjct: 714 VVYPGAITMATTTPSPQMTSDCSSTSASPEPSLPVIQSTYGMKTDGGSLAGN---EMING 770 Query: 721 EIYDE-YDEEEDDPDVDYGSDSENHIAGQAN 750 E E YD+ EDDP DY S++E A AN Sbjct: 771 EDEMEMYDDYEDDPKSDYSSENEAPEAVSAN 801 >gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo sapiens] Length = 804 Score = 843 bits (2179), Expect = 0.0 Identities = 481/811 (59%), Positives = 571/811 (70%), Gaps = 71/811 (8%) Query: 1 MSSKRPASPYG-EADGEVAM---VTSRQKVEEEESDGLPAFHLPLHVSFPNKPHSEEFQP 56 MSSK+ SP+ ADGE AM +TSR+K EE SD A HLPLH NKPHSEE Sbjct: 4 MSSKQATSPFACAADGEDAMTQDLTSREK--EEGSDQHVASHLPLHPIMHNKPHSEELPT 61 Query: 57 VSLLTQETCGHRTPTSQHNTMEVDGNKVMSSFAPHNSSTSPQKAEEGGRQSGESLSSTAL 116 + Q+ + S ME + NK+ S ++ N+STSP K +EG R E ++S Sbjct: 62 LVSTIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDR-EIMTSVTF 120 Query: 117 GTPERRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAMGSGNF-GEI 175 GTPERRKGSLADVVDTLKQ+K+EE+ + E E++ +EKLLSKDWK+K+ + + GEI Sbjct: 121 GTPERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEI 180 Query: 176 KGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQI 235 KGTPESLAEKERQL MI QL SLREQLLAAHDEQKKLAASQIEKQRQQM+LA+QQQEQI Sbjct: 181 KGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQI 240 Query: 236 ARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAA--QQGFLLPPGFSY 293 ARQQQQLLQQQHKINLLQQQIQVQG +PPLMIP+FP DQRTLAAAA QQGFL PPG +Y Sbjct: 241 ARQQQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITY 300 Query: 294 KAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQQLYAAQLAAMQVSPGGKLPGIPQG-NL 352 K G D YPVQ IP+TMAAAAA+ GL PLQLQQLYAAQLA+MQVSPG K+P PQ N Sbjct: 301 KPG--DNYPVQFIPSTMAAAAAS--GLSPLQLQQLYAAQLASMQVSPGAKMPSTPQPPNT 356 Query: 353 GAAVSPTSIHTDKSTNSPPPKSKDEVA-QPLNLSAKPKTSDG-KSPTSPTSPHMPALRIN 410 VSPT I +K SP + KDE A QPLNLS++PKT++ KSPTSPT PA + + Sbjct: 357 AGTVSPTGIKNEKRGTSPVTQVKDEAAAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTS 416 Query: 411 SGAGPLKASVPAALASPSARVSTIG-----------------------YLNDHDAVTKAI 447 P K+S+P+ + R S++G D D V KAI Sbjct: 417 PVNLPNKSSIPSPIGGSLGRGSSLGKWKSQHQEETYELDILSSLNSPALFGDQDTVMKAI 476 Query: 448 QEARQMKEQLRREQQV-----LDGKVAVVNSLGLNNCRTEKEKTTLESLTQQLAVKQNEE 502 QEAR+M+EQ++REQQ +DGK++ +N++GLN+CR EKE+T E+L QL K NE+ Sbjct: 477 QEARKMREQIQREQQQQQPHGVDGKLSSINNMGLNSCRNEKERTRFENLGPQLTGKSNED 536 Query: 503 GKFSHAMMDFNLSGDSDGS--------------------AGVSESRIYRESRGRGSNEPH 542 GK ++D D++GS A V+E+R+YR++RGR S+EPH Sbjct: 537 GKLGPGVIDLTRPEDAEGSKAMNGSAAKLQQYYCWPTGGATVAEARVYRDARGRASSEPH 596 Query: 543 IKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQ 602 IKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWK+M+N EKQPYYEEQARLSK Sbjct: 597 IKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKI 656 Query: 603 HLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIAT-AG 661 HLEKYP+YKYKPRPKRTC+VDGKKLRIGEYK +MR+RRQEMRQ+F VGQQ QIPI T G Sbjct: 657 HLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGTG 716 Query: 662 VVYPGAIAMA-GMPSPHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEIQAEDING 720 VVYPGAI MA PSP + S+ SS S+SPEP +PVIQSTYG+K + + E ING Sbjct: 717 VVYPGAITMATTTPSPQMTSDCSSTSASPEPSLPVIQSTYGMKTDGGSLAGN---EMING 773 Query: 721 EIYDE-YDEEEDDPDVDYGSDSENHIAGQAN 750 E E YD+ EDDP DY S++E A AN Sbjct: 774 EDEMEMYDDYEDDPKSDYSSENEAPEAVSAN 804 >gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo sapiens] Length = 808 Score = 838 bits (2166), Expect = 0.0 Identities = 480/818 (58%), Positives = 571/818 (69%), Gaps = 78/818 (9%) Query: 1 MSSKRPASPYG-EADGEVAM---VTSRQKVEEEESDGLPAFHLPLHVSFPNKPHSEEFQP 56 MSSK+ SP+ ADGE AM +TSR+K EE SD A HLPLH NKPHSEE Sbjct: 1 MSSKQATSPFACAADGEDAMTQDLTSREK--EEGSDQHVASHLPLHPIMHNKPHSEELPT 58 Query: 57 VSLLTQETCGHRTPTSQHNTMEVDGNKVMSSFAPHNSSTSPQKAEEGGRQSGESLSSTAL 116 + Q+ + S ME + NK+ S ++ N+STSP K +EG R E ++S Sbjct: 59 LVSTIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDR-EIMTSVTF 117 Query: 117 GTPERRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAMGSGNF-GEI 175 GTPERRKGSLADVVDTLKQ+K+EE+ + E E++ +EKLLSKDWK+K+ + + GEI Sbjct: 118 GTPERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEI 177 Query: 176 KGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQI 235 KGTPESLAEKERQL MI QL SLREQLLAAHDEQKKLAASQIEKQRQQM+LA+QQQEQI Sbjct: 178 KGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQI 237 Query: 236 ARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAA--QQGFLLPPGFSY 293 ARQQQQLLQQQHKINLLQQQIQVQG +PPLMIP+FP DQRTLAAAA QQGFL PPG +Y Sbjct: 238 ARQQQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITY 297 Query: 294 KAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQ--------------------------- 326 K G D YPVQ IP+TMAAAAA+ GL PLQLQ Sbjct: 298 KPG--DNYPVQFIPSTMAAAAAS--GLSPLQLQKGHVSHPQINQRLKGLSDRFGRNLDTF 353 Query: 327 --------------QLYAAQLAAMQVSPGGKLPGIPQG-NLGAAVSPTSIHTDKSTNSPP 371 QLYAAQLA+MQVSPG K+P PQ N VSPT I +K SP Sbjct: 354 EHGGGHSYNHKQIEQLYAAQLASMQVSPGAKMPSTPQPPNTAGTVSPTGIKNEKRGTSPV 413 Query: 372 PKSKDEVA-QPLNLSAKPKTSDG-KSPTSPTSPHMPALRINSGAGPLKASVPAALASPSA 429 + KDE A QPLNLS++PKT++ KSPTSPT PA + + P K+S+P+ + Sbjct: 414 TQVKDEAAAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTSPVNLPNKSSIPSPIGGSLG 473 Query: 430 RVSTIGYLN---------DHDAVTKAIQEARQMKEQLRREQQV-----LDGKVAVVNSLG 475 R S++ L+ D D V KAIQEAR+M+EQ++REQQ +DGK++ +N++G Sbjct: 474 RGSSLDILSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQQPHGVDGKLSSINNMG 533 Query: 476 LNNCRTEKEKTTLESLTQQLAVKQNEEGKFSHAMMDFNLSGDSDGSAGVSESRIYRESRG 535 LN+CR EKE+T E+L QL K NE+GK ++D D++G A V+E+R+YR++RG Sbjct: 534 LNSCRNEKERTRFENLGPQLTGKSNEDGKLGPGVIDLTRPEDAEGGATVAEARVYRDARG 593 Query: 536 RGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEE 595 R S+EPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWK+M+N EKQPYYEE Sbjct: 594 RASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEE 653 Query: 596 QARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQI 655 QARLSK HLEKYP+YKYKPRPKRTC+VDGKKLRIGEYK +MR+RRQEMRQ+F VGQQ QI Sbjct: 654 QARLSKIHLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQFFTVGQQPQI 713 Query: 656 PIAT-AGVVYPGAIAMA-GMPSPHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEI 713 PI T GVVYPGAI MA PSP + S+ SS S+SPEP +PVIQSTYG+K + + Sbjct: 714 PITTGTGVVYPGAITMATTTPSPQMTSDCSSTSASPEPSLPVIQSTYGMKTDGGSLAGN- 772 Query: 714 QAEDINGEIYDE-YDEEEDDPDVDYGSDSENHIAGQAN 750 E INGE E YD+ EDDP DY S++E A AN Sbjct: 773 --EMINGEDEMEMYDDYEDDPKSDYSSENEAPEAVSAN 808 >gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Homo sapiens] Length = 841 Score = 828 bits (2139), Expect = 0.0 Identities = 481/838 (57%), Positives = 572/838 (68%), Gaps = 98/838 (11%) Query: 1 MSSKRPASPYG-EADGEVAM---VTSRQKVEEEESDGLPAFHLPLHVSFPNKPHSEEFQP 56 MSSK+ SP+ ADGE AM +TSR+K EE SD A HLPLH NKPHSEE Sbjct: 14 MSSKQATSPFACAADGEDAMTQDLTSREK--EEGSDQHVASHLPLHPIMHNKPHSEELPT 71 Query: 57 VSLLTQETCGHRTPTSQHNTMEVDGNKVMSSFAPHNSSTSPQKAEEGGRQSGESLSSTAL 116 + Q+ + S ME + NK+ S ++ N+STSP K +EG R E ++S Sbjct: 72 LVSTIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDR-EIMTSVTF 130 Query: 117 GTPERRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAMGSGNF-GEI 175 GTPERRKGSLADVVDTLKQ+K+EE+ + E E++ +EKLLSKDWK+K+ + + GEI Sbjct: 131 GTPERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEI 190 Query: 176 KGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQI 235 KGTPESLAEKERQL MI QL SLREQLLAAHDEQKKLAASQIEKQRQQM+LA+QQQEQI Sbjct: 191 KGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQI 250 Query: 236 ARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAA--QQGFLLPPGFSY 293 ARQQQQLLQQQHKINLLQQQIQVQG +PPLMIP+FP DQRTLAAAA QQGFL PPG +Y Sbjct: 251 ARQQQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITY 310 Query: 294 KAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQ--------------------------- 326 K G D YPVQ IP+TMAAAAA+ GL PLQLQ Sbjct: 311 KPG--DNYPVQFIPSTMAAAAAS--GLSPLQLQKGHVSHPQINQRLKGLSDRFGRNLDTF 366 Query: 327 --------------QLYAAQLAAMQVSPGGKLPGIPQG-NLGAAVSPTSIHTDKSTNSPP 371 QLYAAQLA+MQVSPG K+P PQ N VSPT I +K SP Sbjct: 367 EHGGGHSYNHKQIEQLYAAQLASMQVSPGAKMPSTPQPPNTAGTVSPTGIKNEKRGTSPV 426 Query: 372 PKSKDEVA-QPLNLSAKPKTSDG-KSPTSPTSPHMPALRINSGAGPLKASVPAALASPSA 429 + KDE A QPLNLS++PKT++ KSPTSPT PA + + P K+S+P+ + Sbjct: 427 TQVKDEAAAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTSPVNLPNKSSIPSPIGGSLG 486 Query: 430 RVSTIGYLN---------DHDAVTKAIQEARQMKEQLRREQQV-----LDGKVAVVNSLG 475 R S++ L+ D D V KAIQEAR+M+EQ++REQQ +DGK++ +N++G Sbjct: 487 RGSSLDILSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQQPHGVDGKLSSINNMG 546 Query: 476 LNNCRTEKEKTTLESLTQQLAVKQNEEGKFSHAMMDFNLSGDSDGS-------------- 521 LN+CR EKE+T E+L QL K NE+GK ++D D++GS Sbjct: 547 LNSCRNEKERTRFENLGPQLTGKSNEDGKLGPGVIDLTRPEDAEGSKAMNGSAAKLQQYY 606 Query: 522 ------AGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISK 575 A V+E+R+YR++RGR S+EPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISK Sbjct: 607 CWPTGGATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISK 666 Query: 576 ILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAI 635 ILGSRWK+M+N EKQPYYEEQARLSK HLEKYP+YKYKPRPKRTC+VDGKKLRIGEYK + Sbjct: 667 ILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQL 726 Query: 636 MRNRRQEMRQYFNVGQQAQIPIAT-AGVVYPGAIAMA-GMPSPHLPSEHSSVSSSPEPGM 693 MR+RRQEMRQ+F VGQQ QIPI T GVVYPGAI MA PSP + S+ SS S+SPEP + Sbjct: 727 MRSRRQEMRQFFTVGQQPQIPITTGTGVVYPGAITMATTTPSPQMTSDCSSTSASPEPSL 786 Query: 694 PVIQSTYGVKGEEPHIKEEIQAEDINGEIYDE-YDEEEDDPDVDYGSDSENHIAGQAN 750 PVIQSTYG+K + + E INGE E YD+ EDDP DY S++E A AN Sbjct: 787 PVIQSTYGMKTDGGSLAGN---EMINGEDEMEMYDDYEDDPKSDYSSENEAPEAVSAN 841 >gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo sapiens] Length = 377 Score = 754 bits (1948), Expect = 0.0 Identities = 375/375 (100%), Positives = 375/375 (100%) Query: 376 DEVAQPLNLSAKPKTSDGKSPTSPTSPHMPALRINSGAGPLKASVPAALASPSARVSTIG 435 DEVAQPLNLSAKPKTSDGKSPTSPTSPHMPALRINSGAGPLKASVPAALASPSARVSTIG Sbjct: 3 DEVAQPLNLSAKPKTSDGKSPTSPTSPHMPALRINSGAGPLKASVPAALASPSARVSTIG 62 Query: 436 YLNDHDAVTKAIQEARQMKEQLRREQQVLDGKVAVVNSLGLNNCRTEKEKTTLESLTQQL 495 YLNDHDAVTKAIQEARQMKEQLRREQQVLDGKVAVVNSLGLNNCRTEKEKTTLESLTQQL Sbjct: 63 YLNDHDAVTKAIQEARQMKEQLRREQQVLDGKVAVVNSLGLNNCRTEKEKTTLESLTQQL 122 Query: 496 AVKQNEEGKFSHAMMDFNLSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAK 555 AVKQNEEGKFSHAMMDFNLSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAK Sbjct: 123 AVKQNEEGKFSHAMMDFNLSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAK 182 Query: 556 DERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPR 615 DERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPR Sbjct: 183 DERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPR 242 Query: 616 PKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIATAGVVYPGAIAMAGMPS 675 PKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIATAGVVYPGAIAMAGMPS Sbjct: 243 PKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIATAGVVYPGAIAMAGMPS 302 Query: 676 PHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEIQAEDINGEIYDEYDEEEDDPDV 735 PHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEIQAEDINGEIYDEYDEEEDDPDV Sbjct: 303 PHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEIQAEDINGEIYDEYDEEEDDPDV 362 Query: 736 DYGSDSENHIAGQAN 750 DYGSDSENHIAGQAN Sbjct: 363 DYGSDSENHIAGQAN 377 >gi|41406089 SRY-box 13 [Homo sapiens] Length = 622 Score = 431 bits (1107), Expect = e-120 Identities = 285/641 (44%), Positives = 365/641 (56%), Gaps = 95/641 (14%) Query: 94 STSPQKAEEGG-RQSGESLSSTALGTPERRKGSLADVVDTLKQRKMEELIKNEPEETPSI 152 S PQ +G R S + S G+PE ++ +++ +++ + +N E P+I Sbjct: 58 SADPQAPAQGNFRGSWDCSSPEGNGSPEPKRPGVSEAASGSQEKL--DFNRNLKEVVPAI 115 Query: 153 EKLLSKDWKDKLLAMGSGNFGEIKGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKK 212 EKLLS DWK++ L S ++KGT ESLAEKE QL+ MI+QL++LR+QLL AH EQK Sbjct: 116 EKLLSSDWKERFLGRNSMEAKDVKGTQESLAEKELQLLVMIHQLSTLRDQLLTAHSEQKN 175 Query: 213 LAASQIEKQRQQMELAKQQQEQIARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPP 272 +AA EKQ+QQMELA+QQQEQIA+QQQQL+QQQHKINLLQQQIQ Q +P +MIP FPP Sbjct: 176 MAAMLFEKQQQQMELARQQQEQIAKQQQQLIQQQHKINLLQQQIQ-QVNMPYVMIPAFPP 234 Query: 273 DQRTLAAAAQQGFLLPPGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQQLYAAQ 332 + L LP +Q IP P++ Y Q Sbjct: 235 SHQPLPVTPDSQLALP--------------IQPIPCK------------PVE----YPLQ 264 Query: 333 LAAMQVSPGGKLPGIPQGNLGAAVSPTSIHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSD 392 L +P K PG +T+ P E +QPLNL+AKPK Sbjct: 265 LLHSPPAPVVKRPGA-----------------MATHHP----LQEPSQPLNLTAKPK--- 300 Query: 393 GKSPTSPTSPHMPALRINSGAG-PLKASVPAALASPSARVSTIGYLNDHDAVTKAIQEAR 451 +P P + P+L+++S P P S +G+L + DAVTKAIQ+AR Sbjct: 301 --APELPNTSSSPSLKMSSCVPRPPSHGGPTRDLQSSPPSLPLGFLGEGDAVTKAIQDAR 358 Query: 452 QMKEQLRREQQVLDGKVAVVNSLGLNNCRTEKEKTTLESLTQQLAVKQNEEGKFSHAMMD 511 Q+ L LDG N K+ +L+S K+ E H + + Sbjct: 359 QL---LHSHSGALDGSP---------NTPFRKDLISLDSSP----AKERLEDGCVHPLEE 402 Query: 512 FNLSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNS 571 LS D DGS ESR N HIKRPMNAFMVWAKDERRKILQAFPDMHNS Sbjct: 403 AMLSCDMDGSRHFPESR----------NSSHIKRPMNAFMVWAKDERRKILQAFPDMHNS 452 Query: 572 NISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGE 631 +ISKILGSRWK+MTN EKQPYYEEQARLS+QHLEKYPDYKYKPRPKRTC+V+GK+LR+GE Sbjct: 453 SISKILGSRWKSMTNQEKQPYYEEQARLSRQHLEKYPDYKYKPRPKRTCIVEGKRLRVGE 512 Query: 632 YKAIMRNRRQEMRQYFNVGQQA-QIPIATAGVVYPGAIAMAGMPSPHLPSEHSSVSSSPE 690 YKA+MR RRQ+ RQ + + QA Q+ ++++ V+YP A AGMP EH V S + Sbjct: 513 YKALMRTRRQDARQSYVIPPQAGQVQMSSSDVLYPRA---AGMPLAQPLVEH-YVPRSLD 568 Query: 691 PGMPVIQSTYGVKGEEPHIKEEIQAEDINGEIYDEYDEEED 731 P MPVI +T ++ E + D GE+Y Y E+ED Sbjct: 569 PNMPVIVNTCSLREEGEGTDDRHSVAD--GEMY-RYSEDED 606 >gi|11967991 SRY-box 17 [Homo sapiens] Length = 414 Score = 112 bits (279), Expect = 2e-24 Identities = 49/108 (45%), Positives = 73/108 (67%), Gaps = 5/108 (4%) Query: 511 DFNLSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHN 570 D + G++ ++G + GR E I+RPMNAFMVWAKDER+++ Q PD+HN Sbjct: 41 DMKVKGEAPANSGAPAG-----AAGRAKGESRIRRPMNAFMVWAKDERKRLAQQNPDLHN 95 Query: 571 SNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKR 618 + +SK+LG WKA+T EK+P+ EE RL QH++ +P+YKY+PR ++ Sbjct: 96 AELSKMLGKSWKALTLAEKRPFVEEAERLRVQHMQDHPNYKYRPRRRK 143 >gi|13899269 SRY-box 7 [Homo sapiens] Length = 388 Score = 109 bits (273), Expect = 8e-24 Identities = 51/102 (50%), Positives = 72/102 (70%), Gaps = 1/102 (0%) Query: 517 DSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKI 576 D++ S G S + R +GS E I+RPMNAFMVWAKDER+++ PD+HN+ +SK+ Sbjct: 20 DAELSDGQSPPAVPRPPGDKGS-ESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKM 78 Query: 577 LGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKR 618 LG WKA+T +K+PY +E RL QH++ YP+YKY+PR K+ Sbjct: 79 LGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKK 120 >gi|4557853 transcription factor SOX9 [Homo sapiens] Length = 509 Score = 109 bits (273), Expect = 8e-24 Identities = 60/165 (36%), Positives = 87/165 (52%), Gaps = 18/165 (10%) Query: 535 GRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYE 594 G N+PH+KRPMNAFMVWA+ RRK+ +P +HN+ +SK LG W+ + EK+P+ E Sbjct: 97 GSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVE 156 Query: 595 EQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQ 654 E RL QH + +PDYKY+PR + K ++ G+ +A +E + ++ A Sbjct: 157 EAERLRVQHKKDHPDYKYQPRRR-------KSVKNGQAEA------EEATEQTHISPNAI 203 Query: 655 IPIATAGVVYPGAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQST 699 A + + +GM H P EHS S P P P T Sbjct: 204 FKALQADSPH----SSSGMSEVHSPGEHSGQSQGP-PTPPTTPKT 243 >gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens] Length = 391 Score = 106 bits (264), Expect = 9e-23 Identities = 51/114 (44%), Positives = 70/114 (61%) Query: 513 NLSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSN 572 NLSG + G G +N+ +KRPMNAFMVW++ +RRK+ Q P MHNS Sbjct: 21 NLSGPAGAGGGGGGGGGGGGGGGAKANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSE 80 Query: 573 ISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKK 626 ISK LG+ WK M+ EK+P+ +E RL H++++PDYKY+PR K L+ K Sbjct: 81 ISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLLKKDK 134 >gi|4507161 SRY-box 11 [Homo sapiens] Length = 441 Score = 105 bits (262), Expect = 2e-22 Identities = 47/76 (61%), Positives = 57/76 (75%) Query: 542 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSK 601 HIKRPMNAFMVW+K ERRKI++ PDMHN+ ISK LG RWK + + EK P+ E RL Sbjct: 48 HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107 Query: 602 QHLEKYPDYKYKPRPK 617 +H+ YPDYKY+PR K Sbjct: 108 KHMADYPDYKYRPRKK 123 >gi|4759162 SRY-box 14 [Homo sapiens] Length = 240 Score = 105 bits (261), Expect = 2e-22 Identities = 45/76 (59%), Positives = 59/76 (77%) Query: 542 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSK 601 HIKRPMNAFMVW++ +RRK+ Q P MHNS ISK LG+ WK ++ EK+PY +E RL Sbjct: 7 HIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRA 66 Query: 602 QHLEKYPDYKYKPRPK 617 QH++++PDYKY+PR K Sbjct: 67 QHMKEHPDYKYRPRRK 82 >gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens] Length = 446 Score = 104 bits (260), Expect = 3e-22 Identities = 50/114 (43%), Positives = 72/114 (63%), Gaps = 3/114 (2%) Query: 513 NLSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSN 572 N +G ++ G S G G+++ +KRPMNAFMVW++ +RRK+ P MHNS Sbjct: 112 NAAGGANSGGGSSGGA---SGGGGGTDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSE 168 Query: 573 ISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKK 626 ISK LG+ WK +T+ EK+P+ +E RL H+++YPDYKY+PR K L+ K Sbjct: 169 ISKRLGADWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDK 222 >gi|8924248 SRY-box 18 [Homo sapiens] Length = 384 Score = 103 bits (258), Expect = 4e-22 Identities = 47/88 (53%), Positives = 64/88 (72%), Gaps = 4/88 (4%) Query: 535 GRG----SNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQ 590 GRG ++E I+RPMNAFMVWAKDER+++ Q PD+HN+ +SK+LG WK + EK+ Sbjct: 73 GRGERQAADESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGKAWKELNAAEKR 132 Query: 591 PYYEEQARLSKQHLEKYPDYKYKPRPKR 618 P+ EE RL QHL +P+YKY+PR K+ Sbjct: 133 PFVEEAERLRVQHLRDHPNYKYRPRRKK 160 >gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens] Length = 315 Score = 103 bits (256), Expect = 8e-22 Identities = 45/76 (59%), Positives = 57/76 (75%) Query: 542 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSK 601 HIKRPMNAFMVW++ ERRKI+ +PDMHN+ ISK LG RW+ + + EK P+ E RL Sbjct: 39 HIKRPMNAFMVWSQHERRKIMDQWPDMHNAEISKRLGRRWQLLQDSEKIPFVREAERLRL 98 Query: 602 QHLEKYPDYKYKPRPK 617 +H+ YPDYKY+PR K Sbjct: 99 KHMADYPDYKYRPRKK 114 >gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens] Length = 474 Score = 102 bits (255), Expect = 1e-21 Identities = 45/76 (59%), Positives = 57/76 (75%) Query: 542 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSK 601 HIKRPMNAFMVW++ ERRKI++ PDMHN+ ISK LG RWK + + +K P+ E RL Sbjct: 58 HIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRL 117 Query: 602 QHLEKYPDYKYKPRPK 617 +H+ YPDYKY+PR K Sbjct: 118 KHMADYPDYKYRPRKK 133 >gi|5902108 SRY-box 21 [Homo sapiens] Length = 276 Score = 102 bits (255), Expect = 1e-21 Identities = 45/85 (52%), Positives = 61/85 (71%) Query: 542 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSK 601 H+KRPMNAFMVW++ +RRK+ Q P MHNS ISK LG+ WK +T EK+P+ +E RL Sbjct: 7 HVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRA 66 Query: 602 QHLEKYPDYKYKPRPKRTCLVDGKK 626 H++++PDYKY+PR K L+ K Sbjct: 67 MHMKEHPDYKYRPRRKPKTLLKKDK 91 >gi|28195386 sex-determining region Y-box 2 [Homo sapiens] Length = 317 Score = 101 bits (252), Expect = 2e-21 Identities = 52/121 (42%), Positives = 72/121 (59%), Gaps = 3/121 (2%) Query: 509 MMDFNLS--GDSDGSAGVSESRIYRESRGRGSNEP-HIKRPMNAFMVWAKDERRKILQAF 565 MM+ L G S G + + G N P +KRPMNAFMVW++ +RRK+ Q Sbjct: 4 MMETELKPPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQEN 63 Query: 566 PDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGK 625 P MHNS ISK LG+ WK ++ EK+P+ +E RL H++++PDYKY+PR K L+ Sbjct: 64 PKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKD 123 Query: 626 K 626 K Sbjct: 124 K 124 >gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens] Length = 466 Score = 100 bits (248), Expect = 6e-21 Identities = 40/84 (47%), Positives = 59/84 (70%) Query: 535 GRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYE 594 G ++PH+KRPMNAFMVWA+ RRK+ +P +HN+ +SK LG W+ + +K+P+ E Sbjct: 96 GASKSKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESDKRPFIE 155 Query: 595 EQARLSKQHLEKYPDYKYKPRPKR 618 E RL QH + +PDYKY+PR ++ Sbjct: 156 EAERLRMQHKKDHPDYKYQPRRRK 179 >gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens] Length = 446 Score = 99.4 bits (246), Expect = 1e-20 Identities = 40/80 (50%), Positives = 59/80 (73%) Query: 540 EPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARL 599 +PH+KRPMNAFMVWA+ RRK+ +P +HN+ +SK LG W+ ++ EK+P+ EE RL Sbjct: 99 KPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERL 158 Query: 600 SKQHLEKYPDYKYKPRPKRT 619 QH + +PDYKY+PR +++ Sbjct: 159 RVQHKKDHPDYKYQPRRRKS 178 >gi|4507225 sex determining region Y [Homo sapiens] Length = 204 Score = 98.2 bits (243), Expect = 2e-20 Identities = 43/86 (50%), Positives = 60/86 (69%) Query: 536 RGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEE 595 +G+ + +KRPMNAF+VW++D+RRK+ P M NS ISK LG +WK +T EK P+++E Sbjct: 53 KGNVQDRVKRPMNAFIVWSRDQRRKMALENPRMRNSEISKQLGYQWKMLTEAEKWPFFQE 112 Query: 596 QARLSKQHLEKYPDYKYKPRPKRTCL 621 +L H EKYP+YKY+PR K L Sbjct: 113 AQKLQAMHREKYPNYKYRPRRKAKML 138 >gi|5902106 SRY-box 15 [Homo sapiens] Length = 233 Score = 97.8 bits (242), Expect = 3e-20 Identities = 50/104 (48%), Positives = 64/104 (61%), Gaps = 7/104 (6%) Query: 521 SAGVSESRIYRESRGRGSNEP-------HIKRPMNAFMVWAKDERRKILQAFPDMHNSNI 573 +A S S +E G GS +KRPMNAFMVW+ +RR++ Q P MHNS I Sbjct: 20 TAAASSSSGPQEREGAGSPAAPGTLPLEKVKRPMNAFMVWSSAQRRQMAQQNPKMHNSEI 79 Query: 574 SKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPK 617 SK LG++WK + EK+P+ EE RL +HL YPDYKY+PR K Sbjct: 80 SKRLGAQWKLLDEDEKRPFVEEAKRLRARHLRDYPDYKYRPRRK 123 >gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo sapiens] Length = 501 Score = 82.0 bits (201), Expect = 2e-15 Identities = 36/95 (37%), Positives = 60/95 (63%), Gaps = 6/95 (6%) Query: 522 AGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRW 581 AG+ ++ ++ G H+KRPMNAFMVWA+ R + +A P +N+ IS LG W Sbjct: 322 AGIPDTPFSKDRNG------HVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEW 375 Query: 582 KAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRP 616 ++ +K+PYY+E ++ ++H E++P + Y+PRP Sbjct: 376 NKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRP 410 >gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Homo sapiens] Length = 753 Score = 82.0 bits (201), Expect = 2e-15 Identities = 36/95 (37%), Positives = 60/95 (63%), Gaps = 6/95 (6%) Query: 522 AGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRW 581 AG+ ++ ++ G H+KRPMNAFMVWA+ R + +A P +N+ IS LG W Sbjct: 322 AGIPDTPFSKDRNG------HVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEW 375 Query: 582 KAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRP 616 ++ +K+PYY+E ++ ++H E++P + Y+PRP Sbjct: 376 NKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRP 410 >gi|112421108 capicua homolog [Homo sapiens] Length = 1608 Score = 71.6 bits (174), Expect = 2e-12 Identities = 37/117 (31%), Positives = 62/117 (52%), Gaps = 3/117 (2%) Query: 532 ESRGRGSNE---PHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLE 588 E GR N+ HI+RPMNAFM+++K R + Q P+ N +SKILG W A+ E Sbjct: 186 EKDGRSPNKREKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKE 245 Query: 589 KQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQ 645 KQ Y++ ++ + H + +PD+K+ + ++ + K +G R + M + Sbjct: 246 KQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLGLAGGHKETRERSMSE 302 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 63.9 bits (154), Expect = 5e-10 Identities = 98/394 (24%), Positives = 158/394 (40%), Gaps = 84/394 (21%) Query: 57 VSLLTQETCGHRTPTSQHNTMEVDGNKVMSSFAPHNSSTSPQKAEEGGRQSGESLSSTAL 116 V++L Q+ G P H + + ++V+SS PQ A++G G L + Sbjct: 3807 VAVLQQQHPGALGPQGPHRQVLMTQSRVLSS---------PQLAQQGQGLMGHRLVTAQQ 3857 Query: 117 GTPERR---KGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAMGSGNFG 173 +++ +GS+A + L+Q L+S + KL A G+ Sbjct: 3858 QQQQQQHQQQGSMAGL-SHLQQ------------------SLMSHSGQPKLSAQPMGSLQ 3898 Query: 174 EIKGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQE 233 +++ ++Q + QL ++Q L +Q++L Q+++Q+QQ +L +QQQ+ Sbjct: 3899 QLQ---------QQQQLQQQQQLQQQQQQQL---QQQQQLQQQQLQQQQQQQQLQQQQQQ 3946 Query: 234 QIARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAA---AAQQGFLLPPG 290 Q+ +QQQQL QQQ + QQ Q Q Q+ L RTL + QQ L PG Sbjct: 3947 QLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLL------NQSRTLLSPQQQQQQQVALGPG 4000 Query: 291 FSYKAGCSDPYPVQLIPTTM-----------AAAAAATPGL-----GPLQLQQLYAAQLA 334 K P L PT + A ++ AT G GPL + Sbjct: 4001 MPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAI----GTTPE 4056 Query: 335 AMQVSPGGKLPGIPQGNLGAAVSPTSIHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSDGK 394 +M PG P + + V P P S ++ PL L + + Sbjct: 4057 SMATEPGEVKPSLSGDSQLLLVQP---------QPQPQPSSLQLQPPLRLPGQQQQQVSL 4107 Query: 395 SPTSPTSPHMPALRINSGAGPLKASVPAALASPS 428 T+ H ++ SG+ +SVP LA PS Sbjct: 4108 LHTAGGGSHG---QLGSGSSSEASSVPHLLAQPS 4138 Score = 36.6 bits (83), Expect = 0.088 Identities = 26/80 (32%), Positives = 43/80 (53%), Gaps = 5/80 (6%) Query: 209 EQKKLAASQIEKQRQQMELAKQQQEQIARQQQQLLQQQHKINLLQ-QQIQVQGQLPPLMI 267 + + L Q++ Q+Q+M+LA++ Q+ QQQQ QQQH + + QQ Q QG Sbjct: 3712 DSRLLQERQLQLQQQRMQLAQKLQQ----QQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQ 3767 Query: 268 PVFPPDQRTLAAAAQQGFLL 287 + P Q + ++ QG L+ Sbjct: 3768 ALGPKPQGLMPPSSHQGLLV 3787 Score = 35.4 bits (80), Expect = 0.20 Identities = 33/137 (24%), Positives = 51/137 (37%), Gaps = 2/137 (1%) Query: 263 PPLMIPVFPPDQRTLAAAAQQGFLLPPGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGP 322 PP P+ PP + + + + L P F P L P A+ + P P Sbjct: 575 PPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSP 634 Query: 323 LQLQQLYAAQLAAMQVSPGGKLPGIPQGNLGAAVSPTSIHTDKSTNSPPPKSKDEVAQPL 382 + + +VS LP + + + SP S ++S SPPP++ P Sbjct: 635 MSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPE 694 Query: 383 NLSAKPKTSDGKSPTSP 399 + P D SP SP Sbjct: 695 DSPTSPPPED--SPASP 709 Score = 33.9 bits (76), Expect = 0.57 Identities = 51/188 (27%), Positives = 71/188 (37%), Gaps = 31/188 (16%) Query: 187 RQLMGMINQLTSLREQLLAAHDEQKKLAASQI----------EKQRQQMELAKQQQEQIA 236 +QL+ M QL L EQ+ +K L A Q E ++++L +QQ +I Sbjct: 3518 QQLLQM--QLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQ 3575 Query: 237 RQQQQLLQQQHK-INLL---------QQQIQVQGQLPPLMIPVFPPDQRTLAAAAQQGFL 286 +Q Q+ +QQ + NL+ QQQ Q Q Q + P Q G L Sbjct: 3576 KQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQL 3635 Query: 287 LP-PGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGPL-------QLQQLYAAQLAAMQV 338 LP G G L T A PG GP Q QQ ++ ++ Sbjct: 3636 LPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPG-GPFLNTALAQQQQQQHSGGAGSLAG 3694 Query: 339 SPGGKLPG 346 GG PG Sbjct: 3695 PSGGFFPG 3702 Score = 32.7 bits (73), Expect = 1.3 Identities = 48/184 (26%), Positives = 68/184 (36%), Gaps = 48/184 (26%) Query: 264 PLMIPVFPPDQRTLAAAAQQGFLLPPGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGPL 323 P +P+ P + +L+ L+PP DP P L P AAA P L P Sbjct: 912 PEELPLSPSGEPSLSPQ-----LMPP---------DPLPPPLSP---IITAAAPPALSP- 953 Query: 324 QLQQLYAAQLAAMQVSPGGKLPGIPQGNLGAAVSPTSIHTDKSTNSPPPKSK---DEVAQ 380 L ++ G K P+ L A + T I SPPP++ E Sbjct: 954 ---------LGELEYPFGAKGDSDPESPLAAPILETPI-------SPPPEANCTDPEPVP 997 Query: 381 PLNLSAKPKTSDGKSPTSP---------TSPHMPALRINSGAGPLKASVPAALASPSARV 431 P+ L P + G P SP SP + + + P + S PA S + + Sbjct: 998 PMILPPSPGSPVG--PASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPL 1055 Query: 432 STIG 435 S IG Sbjct: 1056 SPIG 1059 Score = 30.4 bits (67), Expect = 6.3 Identities = 41/169 (24%), Positives = 55/169 (32%), Gaps = 22/169 (13%) Query: 235 IARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAAQQGFLLPPGFSYK 294 + +QQQQL QQQ + + + P P A L PG Sbjct: 2810 LQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVP 2869 Query: 295 AGCSDPYPVQL---IPTTMAAAAAATPGLGPLQLQQLYAAQLAAMQVSPGGKLPGIPQGN 351 ++L + + PG GP Q + Y +++ P+G Sbjct: 2870 GPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLA--------PEGL 2921 Query: 352 LGAAVSPTSIHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSDGKSPTSPT 400 G AVS PP K A LN S P T K PT PT Sbjct: 2922 RGLAVS----------GLPPQKPSAPPAPELNNSLHP-TPHTKGPTLPT 2959 Score = 30.4 bits (67), Expect = 6.3 Identities = 17/56 (30%), Positives = 29/56 (51%) Query: 179 PESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQ 234 PE+ AEK + + +++ +Q+ E L A KQ+QQ + +QQQ+Q Sbjct: 3557 PEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQ 3612 >gi|195222734 lymphoid enhancer-binding factor 1 isoform 3 [Homo sapiens] Length = 386 Score = 63.2 bits (152), Expect = 9e-10 Identities = 34/139 (24%), Positives = 70/139 (50%), Gaps = 16/139 (11%) Query: 530 YRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEK 589 + + + + PHIK+P+NAFM++ K+ R ++ ++ I++ILG RW A++ E+ Sbjct: 258 HEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQ 317 Query: 590 QPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNV 649 YYE + + H++ YP + + GKK + +R+++++ + Sbjct: 318 AKYYELARKERQLHMQLYPGWSARDN-------YGKK---------KKRKREKLQESASG 361 Query: 650 GQQAQIPIATAGVVYPGAI 668 G+++ P A PG + Sbjct: 362 GKRSSFPTCKAKAATPGPL 380 >gi|226371764 transcription factor 7-like 2 isoform 1 [Homo sapiens] Length = 602 Score = 60.8 bits (146), Expect = 4e-09 Identities = 30/94 (31%), Positives = 54/94 (57%), Gaps = 1/94 (1%) Query: 518 SDGSAGVSESRIYRESRGRGSNE-PHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKI 576 S G S +++S+ + PHIK+P+NAFM++ K+ R K++ ++ I++I Sbjct: 324 SQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQI 383 Query: 577 LGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDY 610 LG RW A++ E+ YYE + + H++ YP + Sbjct: 384 LGRRWHALSREEQAKYYELARKERQLHMQLYPGW 417 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.310 0.127 0.356 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 31,617,953 Number of Sequences: 37866 Number of extensions: 1660805 Number of successful extensions: 16126 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 288 Number of HSP's successfully gapped in prelim test: 552 Number of HSP's that attempted gapping in prelim test: 9426 Number of HSP's gapped (non-prelim): 3833 length of query: 750 length of database: 18,247,518 effective HSP length: 110 effective length of query: 640 effective length of database: 14,082,258 effective search space: 9012645120 effective search space used: 9012645120 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.