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Search of human proteins with 23308713
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23308713 SRY (sex determining region Y)-box 5 isoform a
[Homo sapiens]
(763 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo... 1519 0.0
gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo... 1492 0.0
gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo... 845 0.0
gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Hom... 843 0.0
gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo... 838 0.0
gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Hom... 830 0.0
gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo... 754 0.0
gi|41406089 SRY-box 13 [Homo sapiens] 431 e-120
gi|11967991 SRY-box 17 [Homo sapiens] 112 2e-24
gi|13899269 SRY-box 7 [Homo sapiens] 109 8e-24
gi|4557853 transcription factor SOX9 [Homo sapiens] 109 8e-24
gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens] 106 9e-23
gi|4507161 SRY-box 11 [Homo sapiens] 105 2e-22
gi|4759162 SRY-box 14 [Homo sapiens] 105 2e-22
gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens] 104 3e-22
gi|8924248 SRY-box 18 [Homo sapiens] 103 5e-22
gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens] 103 8e-22
gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens] 102 1e-21
gi|5902108 SRY-box 21 [Homo sapiens] 102 1e-21
gi|28195386 sex-determining region Y-box 2 [Homo sapiens] 101 2e-21
gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens] 100 7e-21
gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens] 99 1e-20
gi|4507225 sex determining region Y [Homo sapiens] 98 3e-20
gi|5902106 SRY-box 15 [Homo sapiens] 98 3e-20
gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo... 82 2e-15
gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Hom... 82 2e-15
gi|112421108 capicua homolog [Homo sapiens] 72 3e-12
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 64 5e-10
gi|195222734 lymphoid enhancer-binding factor 1 isoform 3 [Homo ... 63 9e-10
gi|226371764 transcription factor 7-like 2 isoform 1 [Homo sapiens] 61 4e-09
>gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo
sapiens]
Length = 763
Score = 1519 bits (3932), Expect = 0.0
Identities = 763/763 (100%), Positives = 763/763 (100%)
Query: 1 MLTDPDLPQEFERMSSKRPASPYGEADGEVAMVTSRQKVEEEESDGLPAFHLPLHVSFPN 60
MLTDPDLPQEFERMSSKRPASPYGEADGEVAMVTSRQKVEEEESDGLPAFHLPLHVSFPN
Sbjct: 1 MLTDPDLPQEFERMSSKRPASPYGEADGEVAMVTSRQKVEEEESDGLPAFHLPLHVSFPN 60
Query: 61 KPHSEEFQPVSLLTQETCGHRTPTSQHNTMEVDGNKVMSSFAPHNSSTSPQKAEEGGRQS 120
KPHSEEFQPVSLLTQETCGHRTPTSQHNTMEVDGNKVMSSFAPHNSSTSPQKAEEGGRQS
Sbjct: 61 KPHSEEFQPVSLLTQETCGHRTPTSQHNTMEVDGNKVMSSFAPHNSSTSPQKAEEGGRQS 120
Query: 121 GESLSSTALGTPERRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAM 180
GESLSSTALGTPERRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAM
Sbjct: 121 GESLSSTALGTPERRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAM 180
Query: 181 GSGNFGEIKGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMEL 240
GSGNFGEIKGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMEL
Sbjct: 181 GSGNFGEIKGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMEL 240
Query: 241 AKQQQEQIARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAAQQGFLL 300
AKQQQEQIARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAAQQGFLL
Sbjct: 241 AKQQQEQIARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAAQQGFLL 300
Query: 301 PPGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQQLYAAQLAAMQVSPGGKLPGI 360
PPGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQQLYAAQLAAMQVSPGGKLPGI
Sbjct: 301 PPGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQQLYAAQLAAMQVSPGGKLPGI 360
Query: 361 PQGNLGAAVSPTSIHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSDGKSPTSPTSPHMPAL 420
PQGNLGAAVSPTSIHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSDGKSPTSPTSPHMPAL
Sbjct: 361 PQGNLGAAVSPTSIHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSDGKSPTSPTSPHMPAL 420
Query: 421 RINSGAGPLKASVPAALASPSARVSTIGYLNDHDAVTKAIQEARQMKEQLRREQQVLDGK 480
RINSGAGPLKASVPAALASPSARVSTIGYLNDHDAVTKAIQEARQMKEQLRREQQVLDGK
Sbjct: 421 RINSGAGPLKASVPAALASPSARVSTIGYLNDHDAVTKAIQEARQMKEQLRREQQVLDGK 480
Query: 481 VAVVNSLGLNNCRTEKEKTTLESLTQQLAVKQNEEGKFSHAMMDFNLSGDSDGSAGVSES 540
VAVVNSLGLNNCRTEKEKTTLESLTQQLAVKQNEEGKFSHAMMDFNLSGDSDGSAGVSES
Sbjct: 481 VAVVNSLGLNNCRTEKEKTTLESLTQQLAVKQNEEGKFSHAMMDFNLSGDSDGSAGVSES 540
Query: 541 RIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNL 600
RIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNL
Sbjct: 541 RIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNL 600
Query: 601 EKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYF 660
EKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYF
Sbjct: 601 EKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYF 660
Query: 661 NVGQQAQIPIATAGVVYPGAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEP 720
NVGQQAQIPIATAGVVYPGAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEP
Sbjct: 661 NVGQQAQIPIATAGVVYPGAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEP 720
Query: 721 HIKEEIQAEDINGEIYDEYDEEEDDPDVDYGSDSENHIAGQAN 763
HIKEEIQAEDINGEIYDEYDEEEDDPDVDYGSDSENHIAGQAN
Sbjct: 721 HIKEEIQAEDINGEIYDEYDEEEDDPDVDYGSDSENHIAGQAN 763
>gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo
sapiens]
Length = 750
Score = 1492 bits (3862), Expect = 0.0
Identities = 750/750 (100%), Positives = 750/750 (100%)
Query: 14 MSSKRPASPYGEADGEVAMVTSRQKVEEEESDGLPAFHLPLHVSFPNKPHSEEFQPVSLL 73
MSSKRPASPYGEADGEVAMVTSRQKVEEEESDGLPAFHLPLHVSFPNKPHSEEFQPVSLL
Sbjct: 1 MSSKRPASPYGEADGEVAMVTSRQKVEEEESDGLPAFHLPLHVSFPNKPHSEEFQPVSLL 60
Query: 74 TQETCGHRTPTSQHNTMEVDGNKVMSSFAPHNSSTSPQKAEEGGRQSGESLSSTALGTPE 133
TQETCGHRTPTSQHNTMEVDGNKVMSSFAPHNSSTSPQKAEEGGRQSGESLSSTALGTPE
Sbjct: 61 TQETCGHRTPTSQHNTMEVDGNKVMSSFAPHNSSTSPQKAEEGGRQSGESLSSTALGTPE 120
Query: 134 RRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAMGSGNFGEIKGTPE 193
RRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAMGSGNFGEIKGTPE
Sbjct: 121 RRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAMGSGNFGEIKGTPE 180
Query: 194 SLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQIARQQQ 253
SLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQIARQQQ
Sbjct: 181 SLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQIARQQQ 240
Query: 254 QLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAAQQGFLLPPGFSYKAGCSDP 313
QLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAAQQGFLLPPGFSYKAGCSDP
Sbjct: 241 QLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAAQQGFLLPPGFSYKAGCSDP 300
Query: 314 YPVQLIPTTMAAAAAATPGLGPLQLQQLYAAQLAAMQVSPGGKLPGIPQGNLGAAVSPTS 373
YPVQLIPTTMAAAAAATPGLGPLQLQQLYAAQLAAMQVSPGGKLPGIPQGNLGAAVSPTS
Sbjct: 301 YPVQLIPTTMAAAAAATPGLGPLQLQQLYAAQLAAMQVSPGGKLPGIPQGNLGAAVSPTS 360
Query: 374 IHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSDGKSPTSPTSPHMPALRINSGAGPLKASV 433
IHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSDGKSPTSPTSPHMPALRINSGAGPLKASV
Sbjct: 361 IHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSDGKSPTSPTSPHMPALRINSGAGPLKASV 420
Query: 434 PAALASPSARVSTIGYLNDHDAVTKAIQEARQMKEQLRREQQVLDGKVAVVNSLGLNNCR 493
PAALASPSARVSTIGYLNDHDAVTKAIQEARQMKEQLRREQQVLDGKVAVVNSLGLNNCR
Sbjct: 421 PAALASPSARVSTIGYLNDHDAVTKAIQEARQMKEQLRREQQVLDGKVAVVNSLGLNNCR 480
Query: 494 TEKEKTTLESLTQQLAVKQNEEGKFSHAMMDFNLSGDSDGSAGVSESRIYRESRGRGSNE 553
TEKEKTTLESLTQQLAVKQNEEGKFSHAMMDFNLSGDSDGSAGVSESRIYRESRGRGSNE
Sbjct: 481 TEKEKTTLESLTQQLAVKQNEEGKFSHAMMDFNLSGDSDGSAGVSESRIYRESRGRGSNE 540
Query: 554 PHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLS 613
PHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLS
Sbjct: 541 PHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLS 600
Query: 614 KQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIATA 673
KQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIATA
Sbjct: 601 KQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIATA 660
Query: 674 GVVYPGAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEIQAEDING 733
GVVYPGAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEIQAEDING
Sbjct: 661 GVVYPGAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEIQAEDING 720
Query: 734 EIYDEYDEEEDDPDVDYGSDSENHIAGQAN 763
EIYDEYDEEEDDPDVDYGSDSENHIAGQAN
Sbjct: 721 EIYDEYDEEEDDPDVDYGSDSENHIAGQAN 750
>gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo
sapiens]
Length = 804
Score = 845 bits (2184), Expect = 0.0
Identities = 482/812 (59%), Positives = 572/812 (70%), Gaps = 71/812 (8%)
Query: 13 RMSSKRPASPYG-EADGEVAM---VTSRQKVEEEESDGLPAFHLPLHVSFPNKPHSEEFQ 68
RMSSK+ SP+ ADGE AM +TSR+K EE SD A HLPLH NKPHSEE
Sbjct: 3 RMSSKQATSPFACAADGEDAMTQDLTSREK--EEGSDQHVASHLPLHPIMHNKPHSEELP 60
Query: 69 PVSLLTQETCGHRTPTSQHNTMEVDGNKVMSSFAPHNSSTSPQKAEEGGRQSGESLSSTA 128
+ Q+ + S ME + NK+ S ++ N+STSP K +EG R E ++S
Sbjct: 61 TLVSTIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDR-EIMTSVT 119
Query: 129 LGTPERRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAMGSGNF-GE 187
GTPERRKGSLADVVDTLKQ+K+EE+ + E E++ +EKLLSKDWK+K+ + + GE
Sbjct: 120 FGTPERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGE 179
Query: 188 IKGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQ 247
IKGTPESLAEKERQL MI QL SLREQLLAAHDEQKKLAASQIEKQRQQM+LA+QQQEQ
Sbjct: 180 IKGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQ 239
Query: 248 IARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAA--QQGFLLPPGFS 305
IARQQQQLLQQQHKINLLQQQIQVQG +PPLMIP+FP DQRTLAAAA QQGFL PPG +
Sbjct: 240 IARQQQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGIT 299
Query: 306 YKAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQQLYAAQLAAMQVSPGGKLPGIPQG-N 364
YK G D YPVQ IP+TMAAAAA+ GL PLQLQQLYAAQLA+MQVSPG K+P PQ N
Sbjct: 300 YKPG--DNYPVQFIPSTMAAAAAS--GLSPLQLQQLYAAQLASMQVSPGAKMPSTPQPPN 355
Query: 365 LGAAVSPTSIHTDKSTNSPPPKSKDEVA-QPLNLSAKPKTSDG-KSPTSPTSPHMPALRI 422
VSPT I +K SP + KDE A QPLNLS++PKT++ KSPTSPT PA +
Sbjct: 356 TAGTVSPTGIKNEKRGTSPVTQVKDEAAAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKT 415
Query: 423 NSGAGPLKASVPAALASPSARVSTIG-----------------------YLNDHDAVTKA 459
+ P K+S+P+ + R S++G D D V KA
Sbjct: 416 SPVNLPNKSSIPSPIGGSLGRGSSLGKWKSQHQEETYELDILSSLNSPALFGDQDTVMKA 475
Query: 460 IQEARQMKEQLRREQQV-----LDGKVAVVNSLGLNNCRTEKEKTTLESLTQQLAVKQNE 514
IQEAR+M+EQ++REQQ +DGK++ +N++GLN+CR EKE+T E+L QL K NE
Sbjct: 476 IQEARKMREQIQREQQQQQPHGVDGKLSSINNMGLNSCRNEKERTRFENLGPQLTGKSNE 535
Query: 515 EGKFSHAMMDFNLSGDSDGS--------------------AGVSESRIYRESRGRGSNEP 554
+GK ++D D++GS A V+E+R+YR++RGR S+EP
Sbjct: 536 DGKLGPGVIDLTRPEDAEGSKAMNGSAAKLQQYYCWPTGGATVAEARVYRDARGRASSEP 595
Query: 555 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSK 614
HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWK+M+N EKQPYYEEQARLSK
Sbjct: 596 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSK 655
Query: 615 QHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIAT-A 673
HLEKYP+YKYKPRPKRTC+VDGKKLRIGEYK +MR+RRQEMRQ+F VGQQ QIPI T
Sbjct: 656 IHLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGT 715
Query: 674 GVVYPGAIAMA-GMPSPHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEIQAEDIN 732
GVVYPGAI MA PSP + S+ SS S+SPEP +PVIQSTYG+K + + E IN
Sbjct: 716 GVVYPGAITMATTTPSPQMTSDCSSTSASPEPSLPVIQSTYGMKTDGGSLAGN---EMIN 772
Query: 733 GEIYDE-YDEEEDDPDVDYGSDSENHIAGQAN 763
GE E YD+ EDDP DY S++E A AN
Sbjct: 773 GEDEMEMYDDYEDDPKSDYSSENEAPEAVSAN 804
>gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Homo
sapiens]
Length = 801
Score = 843 bits (2179), Expect = 0.0
Identities = 481/811 (59%), Positives = 571/811 (70%), Gaps = 71/811 (8%)
Query: 14 MSSKRPASPYG-EADGEVAM---VTSRQKVEEEESDGLPAFHLPLHVSFPNKPHSEEFQP 69
MSSK+ SP+ ADGE AM +TSR+K EE SD A HLPLH NKPHSEE
Sbjct: 1 MSSKQATSPFACAADGEDAMTQDLTSREK--EEGSDQHVASHLPLHPIMHNKPHSEELPT 58
Query: 70 VSLLTQETCGHRTPTSQHNTMEVDGNKVMSSFAPHNSSTSPQKAEEGGRQSGESLSSTAL 129
+ Q+ + S ME + NK+ S ++ N+STSP K +EG R E ++S
Sbjct: 59 LVSTIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDR-EIMTSVTF 117
Query: 130 GTPERRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAMGSGNF-GEI 188
GTPERRKGSLADVVDTLKQ+K+EE+ + E E++ +EKLLSKDWK+K+ + + GEI
Sbjct: 118 GTPERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEI 177
Query: 189 KGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQI 248
KGTPESLAEKERQL MI QL SLREQLLAAHDEQKKLAASQIEKQRQQM+LA+QQQEQI
Sbjct: 178 KGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQI 237
Query: 249 ARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAA--QQGFLLPPGFSY 306
ARQQQQLLQQQHKINLLQQQIQVQG +PPLMIP+FP DQRTLAAAA QQGFL PPG +Y
Sbjct: 238 ARQQQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITY 297
Query: 307 KAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQQLYAAQLAAMQVSPGGKLPGIPQG-NL 365
K G D YPVQ IP+TMAAAAA+ GL PLQLQQLYAAQLA+MQVSPG K+P PQ N
Sbjct: 298 KPG--DNYPVQFIPSTMAAAAAS--GLSPLQLQQLYAAQLASMQVSPGAKMPSTPQPPNT 353
Query: 366 GAAVSPTSIHTDKSTNSPPPKSKDEVA-QPLNLSAKPKTSDG-KSPTSPTSPHMPALRIN 423
VSPT I +K SP + KDE A QPLNLS++PKT++ KSPTSPT PA + +
Sbjct: 354 AGTVSPTGIKNEKRGTSPVTQVKDEAAAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTS 413
Query: 424 SGAGPLKASVPAALASPSARVSTIG-----------------------YLNDHDAVTKAI 460
P K+S+P+ + R S++G D D V KAI
Sbjct: 414 PVNLPNKSSIPSPIGGSLGRGSSLGKWKSQHQEETYELDILSSLNSPALFGDQDTVMKAI 473
Query: 461 QEARQMKEQLRREQQV-----LDGKVAVVNSLGLNNCRTEKEKTTLESLTQQLAVKQNEE 515
QEAR+M+EQ++REQQ +DGK++ +N++GLN+CR EKE+T E+L QL K NE+
Sbjct: 474 QEARKMREQIQREQQQQQPHGVDGKLSSINNMGLNSCRNEKERTRFENLGPQLTGKSNED 533
Query: 516 GKFSHAMMDFNLSGDSDGS--------------------AGVSESRIYRESRGRGSNEPH 555
GK ++D D++GS A V+E+R+YR++RGR S+EPH
Sbjct: 534 GKLGPGVIDLTRPEDAEGSKAMNGSAAKLQQYYCWPTGGATVAEARVYRDARGRASSEPH 593
Query: 556 IKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQ 615
IKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWK+M+N EKQPYYEEQARLSK
Sbjct: 594 IKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLSKI 653
Query: 616 HLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIAT-AG 674
HLEKYP+YKYKPRPKRTC+VDGKKLRIGEYK +MR+RRQEMRQ+F VGQQ QIPI T G
Sbjct: 654 HLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQFFTVGQQPQIPITTGTG 713
Query: 675 VVYPGAIAMA-GMPSPHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEIQAEDING 733
VVYPGAI MA PSP + S+ SS S+SPEP +PVIQSTYG+K + + E ING
Sbjct: 714 VVYPGAITMATTTPSPQMTSDCSSTSASPEPSLPVIQSTYGMKTDGGSLAGN---EMING 770
Query: 734 EIYDE-YDEEEDDPDVDYGSDSENHIAGQAN 763
E E YD+ EDDP DY S++E A AN
Sbjct: 771 EDEMEMYDDYEDDPKSDYSSENEAPEAVSAN 801
>gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo
sapiens]
Length = 808
Score = 838 bits (2166), Expect = 0.0
Identities = 480/818 (58%), Positives = 571/818 (69%), Gaps = 78/818 (9%)
Query: 14 MSSKRPASPYG-EADGEVAM---VTSRQKVEEEESDGLPAFHLPLHVSFPNKPHSEEFQP 69
MSSK+ SP+ ADGE AM +TSR+K EE SD A HLPLH NKPHSEE
Sbjct: 1 MSSKQATSPFACAADGEDAMTQDLTSREK--EEGSDQHVASHLPLHPIMHNKPHSEELPT 58
Query: 70 VSLLTQETCGHRTPTSQHNTMEVDGNKVMSSFAPHNSSTSPQKAEEGGRQSGESLSSTAL 129
+ Q+ + S ME + NK+ S ++ N+STSP K +EG R E ++S
Sbjct: 59 LVSTIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDR-EIMTSVTF 117
Query: 130 GTPERRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAMGSGNF-GEI 188
GTPERRKGSLADVVDTLKQ+K+EE+ + E E++ +EKLLSKDWK+K+ + + GEI
Sbjct: 118 GTPERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEI 177
Query: 189 KGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQI 248
KGTPESLAEKERQL MI QL SLREQLLAAHDEQKKLAASQIEKQRQQM+LA+QQQEQI
Sbjct: 178 KGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQI 237
Query: 249 ARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAA--QQGFLLPPGFSY 306
ARQQQQLLQQQHKINLLQQQIQVQG +PPLMIP+FP DQRTLAAAA QQGFL PPG +Y
Sbjct: 238 ARQQQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITY 297
Query: 307 KAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQ--------------------------- 339
K G D YPVQ IP+TMAAAAA+ GL PLQLQ
Sbjct: 298 KPG--DNYPVQFIPSTMAAAAAS--GLSPLQLQKGHVSHPQINQRLKGLSDRFGRNLDTF 353
Query: 340 --------------QLYAAQLAAMQVSPGGKLPGIPQG-NLGAAVSPTSIHTDKSTNSPP 384
QLYAAQLA+MQVSPG K+P PQ N VSPT I +K SP
Sbjct: 354 EHGGGHSYNHKQIEQLYAAQLASMQVSPGAKMPSTPQPPNTAGTVSPTGIKNEKRGTSPV 413
Query: 385 PKSKDEVA-QPLNLSAKPKTSDG-KSPTSPTSPHMPALRINSGAGPLKASVPAALASPSA 442
+ KDE A QPLNLS++PKT++ KSPTSPT PA + + P K+S+P+ +
Sbjct: 414 TQVKDEAAAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTSPVNLPNKSSIPSPIGGSLG 473
Query: 443 RVSTIGYLN---------DHDAVTKAIQEARQMKEQLRREQQV-----LDGKVAVVNSLG 488
R S++ L+ D D V KAIQEAR+M+EQ++REQQ +DGK++ +N++G
Sbjct: 474 RGSSLDILSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQQPHGVDGKLSSINNMG 533
Query: 489 LNNCRTEKEKTTLESLTQQLAVKQNEEGKFSHAMMDFNLSGDSDGSAGVSESRIYRESRG 548
LN+CR EKE+T E+L QL K NE+GK ++D D++G A V+E+R+YR++RG
Sbjct: 534 LNSCRNEKERTRFENLGPQLTGKSNEDGKLGPGVIDLTRPEDAEGGATVAEARVYRDARG 593
Query: 549 RGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEE 608
R S+EPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWK+M+N EKQPYYEE
Sbjct: 594 RASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEE 653
Query: 609 QARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQI 668
QARLSK HLEKYP+YKYKPRPKRTC+VDGKKLRIGEYK +MR+RRQEMRQ+F VGQQ QI
Sbjct: 654 QARLSKIHLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEMRQFFTVGQQPQI 713
Query: 669 PIAT-AGVVYPGAIAMA-GMPSPHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEI 726
PI T GVVYPGAI MA PSP + S+ SS S+SPEP +PVIQSTYG+K + +
Sbjct: 714 PITTGTGVVYPGAITMATTTPSPQMTSDCSSTSASPEPSLPVIQSTYGMKTDGGSLAGN- 772
Query: 727 QAEDINGEIYDE-YDEEEDDPDVDYGSDSENHIAGQAN 763
E INGE E YD+ EDDP DY S++E A AN
Sbjct: 773 --EMINGEDEMEMYDDYEDDPKSDYSSENEAPEAVSAN 808
>gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Homo
sapiens]
Length = 841
Score = 830 bits (2144), Expect = 0.0
Identities = 482/839 (57%), Positives = 573/839 (68%), Gaps = 98/839 (11%)
Query: 13 RMSSKRPASPYG-EADGEVAM---VTSRQKVEEEESDGLPAFHLPLHVSFPNKPHSEEFQ 68
RMSSK+ SP+ ADGE AM +TSR+K EE SD A HLPLH NKPHSEE
Sbjct: 13 RMSSKQATSPFACAADGEDAMTQDLTSREK--EEGSDQHVASHLPLHPIMHNKPHSEELP 70
Query: 69 PVSLLTQETCGHRTPTSQHNTMEVDGNKVMSSFAPHNSSTSPQKAEEGGRQSGESLSSTA 128
+ Q+ + S ME + NK+ S ++ N+STSP K +EG R E ++S
Sbjct: 71 TLVSTIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSRDR-EIMTSVT 129
Query: 129 LGTPERRKGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAMGSGNF-GE 187
GTPERRKGSLADVVDTLKQ+K+EE+ + E E++ +EKLLSKDWK+K+ + + GE
Sbjct: 130 FGTPERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGE 189
Query: 188 IKGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQ 247
IKGTPESLAEKERQL MI QL SLREQLLAAHDEQKKLAASQIEKQRQQM+LA+QQQEQ
Sbjct: 190 IKGTPESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQ 249
Query: 248 IARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAA--QQGFLLPPGFS 305
IARQQQQLLQQQHKINLLQQQIQVQG +PPLMIP+FP DQRTLAAAA QQGFL PPG +
Sbjct: 250 IARQQQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGIT 309
Query: 306 YKAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQ-------------------------- 339
YK G D YPVQ IP+TMAAAAA+ GL PLQLQ
Sbjct: 310 YKPG--DNYPVQFIPSTMAAAAAS--GLSPLQLQKGHVSHPQINQRLKGLSDRFGRNLDT 365
Query: 340 ---------------QLYAAQLAAMQVSPGGKLPGIPQG-NLGAAVSPTSIHTDKSTNSP 383
QLYAAQLA+MQVSPG K+P PQ N VSPT I +K SP
Sbjct: 366 FEHGGGHSYNHKQIEQLYAAQLASMQVSPGAKMPSTPQPPNTAGTVSPTGIKNEKRGTSP 425
Query: 384 PPKSKDEVA-QPLNLSAKPKTSDG-KSPTSPTSPHMPALRINSGAGPLKASVPAALASPS 441
+ KDE A QPLNLS++PKT++ KSPTSPT PA + + P K+S+P+ +
Sbjct: 426 VTQVKDEAAAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTSPVNLPNKSSIPSPIGGSL 485
Query: 442 ARVSTIGYLN---------DHDAVTKAIQEARQMKEQLRREQQV-----LDGKVAVVNSL 487
R S++ L+ D D V KAIQEAR+M+EQ++REQQ +DGK++ +N++
Sbjct: 486 GRGSSLDILSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQQPHGVDGKLSSINNM 545
Query: 488 GLNNCRTEKEKTTLESLTQQLAVKQNEEGKFSHAMMDFNLSGDSDGS------------- 534
GLN+CR EKE+T E+L QL K NE+GK ++D D++GS
Sbjct: 546 GLNSCRNEKERTRFENLGPQLTGKSNEDGKLGPGVIDLTRPEDAEGSKAMNGSAAKLQQY 605
Query: 535 -------AGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNIS 587
A V+E+R+YR++RGR S+EPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNIS
Sbjct: 606 YCWPTGGATVAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNIS 665
Query: 588 KILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKA 647
KILGSRWK+M+N EKQPYYEEQARLSK HLEKYP+YKYKPRPKRTC+VDGKKLRIGEYK
Sbjct: 666 KILGSRWKSMSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQ 725
Query: 648 IMRNRRQEMRQYFNVGQQAQIPIAT-AGVVYPGAIAMA-GMPSPHLPSEHSSVSSSPEPG 705
+MR+RRQEMRQ+F VGQQ QIPI T GVVYPGAI MA PSP + S+ SS S+SPEP
Sbjct: 726 LMRSRRQEMRQFFTVGQQPQIPITTGTGVVYPGAITMATTTPSPQMTSDCSSTSASPEPS 785
Query: 706 MPVIQSTYGVKGEEPHIKEEIQAEDINGEIYDE-YDEEEDDPDVDYGSDSENHIAGQAN 763
+PVIQSTYG+K + + E INGE E YD+ EDDP DY S++E A AN
Sbjct: 786 LPVIQSTYGMKTDGGSLAGN---EMINGEDEMEMYDDYEDDPKSDYSSENEAPEAVSAN 841
>gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo
sapiens]
Length = 377
Score = 754 bits (1948), Expect = 0.0
Identities = 375/375 (100%), Positives = 375/375 (100%)
Query: 389 DEVAQPLNLSAKPKTSDGKSPTSPTSPHMPALRINSGAGPLKASVPAALASPSARVSTIG 448
DEVAQPLNLSAKPKTSDGKSPTSPTSPHMPALRINSGAGPLKASVPAALASPSARVSTIG
Sbjct: 3 DEVAQPLNLSAKPKTSDGKSPTSPTSPHMPALRINSGAGPLKASVPAALASPSARVSTIG 62
Query: 449 YLNDHDAVTKAIQEARQMKEQLRREQQVLDGKVAVVNSLGLNNCRTEKEKTTLESLTQQL 508
YLNDHDAVTKAIQEARQMKEQLRREQQVLDGKVAVVNSLGLNNCRTEKEKTTLESLTQQL
Sbjct: 63 YLNDHDAVTKAIQEARQMKEQLRREQQVLDGKVAVVNSLGLNNCRTEKEKTTLESLTQQL 122
Query: 509 AVKQNEEGKFSHAMMDFNLSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAK 568
AVKQNEEGKFSHAMMDFNLSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAK
Sbjct: 123 AVKQNEEGKFSHAMMDFNLSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAK 182
Query: 569 DERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPR 628
DERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPR
Sbjct: 183 DERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPR 242
Query: 629 PKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIATAGVVYPGAIAMAGMPS 688
PKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIATAGVVYPGAIAMAGMPS
Sbjct: 243 PKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQIPIATAGVVYPGAIAMAGMPS 302
Query: 689 PHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEIQAEDINGEIYDEYDEEEDDPDV 748
PHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEIQAEDINGEIYDEYDEEEDDPDV
Sbjct: 303 PHLPSEHSSVSSSPEPGMPVIQSTYGVKGEEPHIKEEIQAEDINGEIYDEYDEEEDDPDV 362
Query: 749 DYGSDSENHIAGQAN 763
DYGSDSENHIAGQAN
Sbjct: 363 DYGSDSENHIAGQAN 377
>gi|41406089 SRY-box 13 [Homo sapiens]
Length = 622
Score = 431 bits (1107), Expect = e-120
Identities = 285/641 (44%), Positives = 365/641 (56%), Gaps = 95/641 (14%)
Query: 107 STSPQKAEEGG-RQSGESLSSTALGTPERRKGSLADVVDTLKQRKMEELIKNEPEETPSI 165
S PQ +G R S + S G+PE ++ +++ +++ + +N E P+I
Sbjct: 58 SADPQAPAQGNFRGSWDCSSPEGNGSPEPKRPGVSEAASGSQEKL--DFNRNLKEVVPAI 115
Query: 166 EKLLSKDWKDKLLAMGSGNFGEIKGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKK 225
EKLLS DWK++ L S ++KGT ESLAEKE QL+ MI+QL++LR+QLL AH EQK
Sbjct: 116 EKLLSSDWKERFLGRNSMEAKDVKGTQESLAEKELQLLVMIHQLSTLRDQLLTAHSEQKN 175
Query: 226 LAASQIEKQRQQMELAKQQQEQIARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPP 285
+AA EKQ+QQMELA+QQQEQIA+QQQQL+QQQHKINLLQQQIQ Q +P +MIP FPP
Sbjct: 176 MAAMLFEKQQQQMELARQQQEQIAKQQQQLIQQQHKINLLQQQIQ-QVNMPYVMIPAFPP 234
Query: 286 DQRTLAAAAQQGFLLPPGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQQLYAAQ 345
+ L LP +Q IP P++ Y Q
Sbjct: 235 SHQPLPVTPDSQLALP--------------IQPIPCK------------PVE----YPLQ 264
Query: 346 LAAMQVSPGGKLPGIPQGNLGAAVSPTSIHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSD 405
L +P K PG +T+ P E +QPLNL+AKPK
Sbjct: 265 LLHSPPAPVVKRPGA-----------------MATHHP----LQEPSQPLNLTAKPK--- 300
Query: 406 GKSPTSPTSPHMPALRINSGAG-PLKASVPAALASPSARVSTIGYLNDHDAVTKAIQEAR 464
+P P + P+L+++S P P S +G+L + DAVTKAIQ+AR
Sbjct: 301 --APELPNTSSSPSLKMSSCVPRPPSHGGPTRDLQSSPPSLPLGFLGEGDAVTKAIQDAR 358
Query: 465 QMKEQLRREQQVLDGKVAVVNSLGLNNCRTEKEKTTLESLTQQLAVKQNEEGKFSHAMMD 524
Q+ L LDG N K+ +L+S K+ E H + +
Sbjct: 359 QL---LHSHSGALDGSP---------NTPFRKDLISLDSSP----AKERLEDGCVHPLEE 402
Query: 525 FNLSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNS 584
LS D DGS ESR N HIKRPMNAFMVWAKDERRKILQAFPDMHNS
Sbjct: 403 AMLSCDMDGSRHFPESR----------NSSHIKRPMNAFMVWAKDERRKILQAFPDMHNS 452
Query: 585 NISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGE 644
+ISKILGSRWK+MTN EKQPYYEEQARLS+QHLEKYPDYKYKPRPKRTC+V+GK+LR+GE
Sbjct: 453 SISKILGSRWKSMTNQEKQPYYEEQARLSRQHLEKYPDYKYKPRPKRTCIVEGKRLRVGE 512
Query: 645 YKAIMRNRRQEMRQYFNVGQQA-QIPIATAGVVYPGAIAMAGMPSPHLPSEHSSVSSSPE 703
YKA+MR RRQ+ RQ + + QA Q+ ++++ V+YP A AGMP EH V S +
Sbjct: 513 YKALMRTRRQDARQSYVIPPQAGQVQMSSSDVLYPRA---AGMPLAQPLVEH-YVPRSLD 568
Query: 704 PGMPVIQSTYGVKGEEPHIKEEIQAEDINGEIYDEYDEEED 744
P MPVI +T ++ E + D GE+Y Y E+ED
Sbjct: 569 PNMPVIVNTCSLREEGEGTDDRHSVAD--GEMY-RYSEDED 606
>gi|11967991 SRY-box 17 [Homo sapiens]
Length = 414
Score = 112 bits (279), Expect = 2e-24
Identities = 49/108 (45%), Positives = 73/108 (67%), Gaps = 5/108 (4%)
Query: 524 DFNLSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHN 583
D + G++ ++G + GR E I+RPMNAFMVWAKDER+++ Q PD+HN
Sbjct: 41 DMKVKGEAPANSGAPAG-----AAGRAKGESRIRRPMNAFMVWAKDERKRLAQQNPDLHN 95
Query: 584 SNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKR 631
+ +SK+LG WKA+T EK+P+ EE RL QH++ +P+YKY+PR ++
Sbjct: 96 AELSKMLGKSWKALTLAEKRPFVEEAERLRVQHMQDHPNYKYRPRRRK 143
>gi|13899269 SRY-box 7 [Homo sapiens]
Length = 388
Score = 109 bits (273), Expect = 8e-24
Identities = 51/102 (50%), Positives = 72/102 (70%), Gaps = 1/102 (0%)
Query: 530 DSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKI 589
D++ S G S + R +GS E I+RPMNAFMVWAKDER+++ PD+HN+ +SK+
Sbjct: 20 DAELSDGQSPPAVPRPPGDKGS-ESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKM 78
Query: 590 LGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKR 631
LG WKA+T +K+PY +E RL QH++ YP+YKY+PR K+
Sbjct: 79 LGKSWKALTLSQKRPYVDEAERLRLQHMQDYPNYKYRPRRKK 120
>gi|4557853 transcription factor SOX9 [Homo sapiens]
Length = 509
Score = 109 bits (273), Expect = 8e-24
Identities = 60/165 (36%), Positives = 87/165 (52%), Gaps = 18/165 (10%)
Query: 548 GRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYE 607
G N+PH+KRPMNAFMVWA+ RRK+ +P +HN+ +SK LG W+ + EK+P+ E
Sbjct: 97 GSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVE 156
Query: 608 EQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNVGQQAQ 667
E RL QH + +PDYKY+PR + K ++ G+ +A +E + ++ A
Sbjct: 157 EAERLRVQHKKDHPDYKYQPRRR-------KSVKNGQAEA------EEATEQTHISPNAI 203
Query: 668 IPIATAGVVYPGAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQST 712
A + + +GM H P EHS S P P P T
Sbjct: 204 FKALQADSPH----SSSGMSEVHSPGEHSGQSQGP-PTPPTTPKT 243
>gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]
Length = 391
Score = 106 bits (264), Expect = 9e-23
Identities = 51/114 (44%), Positives = 70/114 (61%)
Query: 526 NLSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSN 585
NLSG + G G +N+ +KRPMNAFMVW++ +RRK+ Q P MHNS
Sbjct: 21 NLSGPAGAGGGGGGGGGGGGGGGAKANQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSE 80
Query: 586 ISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKK 639
ISK LG+ WK M+ EK+P+ +E RL H++++PDYKY+PR K L+ K
Sbjct: 81 ISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLLKKDK 134
>gi|4507161 SRY-box 11 [Homo sapiens]
Length = 441
Score = 105 bits (262), Expect = 2e-22
Identities = 47/76 (61%), Positives = 57/76 (75%)
Query: 555 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSK 614
HIKRPMNAFMVW+K ERRKI++ PDMHN+ ISK LG RWK + + EK P+ E RL
Sbjct: 48 HIKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRL 107
Query: 615 QHLEKYPDYKYKPRPK 630
+H+ YPDYKY+PR K
Sbjct: 108 KHMADYPDYKYRPRKK 123
>gi|4759162 SRY-box 14 [Homo sapiens]
Length = 240
Score = 105 bits (261), Expect = 2e-22
Identities = 45/76 (59%), Positives = 59/76 (77%)
Query: 555 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSK 614
HIKRPMNAFMVW++ +RRK+ Q P MHNS ISK LG+ WK ++ EK+PY +E RL
Sbjct: 7 HIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRA 66
Query: 615 QHLEKYPDYKYKPRPK 630
QH++++PDYKY+PR K
Sbjct: 67 QHMKEHPDYKYRPRRK 82
>gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens]
Length = 446
Score = 104 bits (260), Expect = 3e-22
Identities = 50/114 (43%), Positives = 72/114 (63%), Gaps = 3/114 (2%)
Query: 526 NLSGDSDGSAGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSN 585
N +G ++ G S G G+++ +KRPMNAFMVW++ +RRK+ P MHNS
Sbjct: 112 NAAGGANSGGGSSGGA---SGGGGGTDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSE 168
Query: 586 ISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKK 639
ISK LG+ WK +T+ EK+P+ +E RL H+++YPDYKY+PR K L+ K
Sbjct: 169 ISKRLGADWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDK 222
>gi|8924248 SRY-box 18 [Homo sapiens]
Length = 384
Score = 103 bits (258), Expect = 5e-22
Identities = 47/88 (53%), Positives = 64/88 (72%), Gaps = 4/88 (4%)
Query: 548 GRG----SNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQ 603
GRG ++E I+RPMNAFMVWAKDER+++ Q PD+HN+ +SK+LG WK + EK+
Sbjct: 73 GRGERQAADESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGKAWKELNAAEKR 132
Query: 604 PYYEEQARLSKQHLEKYPDYKYKPRPKR 631
P+ EE RL QHL +P+YKY+PR K+
Sbjct: 133 PFVEEAERLRVQHLRDHPNYKYRPRRKK 160
>gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens]
Length = 315
Score = 103 bits (256), Expect = 8e-22
Identities = 45/76 (59%), Positives = 57/76 (75%)
Query: 555 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSK 614
HIKRPMNAFMVW++ ERRKI+ +PDMHN+ ISK LG RW+ + + EK P+ E RL
Sbjct: 39 HIKRPMNAFMVWSQHERRKIMDQWPDMHNAEISKRLGRRWQLLQDSEKIPFVREAERLRL 98
Query: 615 QHLEKYPDYKYKPRPK 630
+H+ YPDYKY+PR K
Sbjct: 99 KHMADYPDYKYRPRKK 114
>gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]
Length = 474
Score = 102 bits (255), Expect = 1e-21
Identities = 45/76 (59%), Positives = 57/76 (75%)
Query: 555 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSK 614
HIKRPMNAFMVW++ ERRKI++ PDMHN+ ISK LG RWK + + +K P+ E RL
Sbjct: 58 HIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRL 117
Query: 615 QHLEKYPDYKYKPRPK 630
+H+ YPDYKY+PR K
Sbjct: 118 KHMADYPDYKYRPRKK 133
>gi|5902108 SRY-box 21 [Homo sapiens]
Length = 276
Score = 102 bits (255), Expect = 1e-21
Identities = 45/85 (52%), Positives = 61/85 (71%)
Query: 555 HIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSK 614
H+KRPMNAFMVW++ +RRK+ Q P MHNS ISK LG+ WK +T EK+P+ +E RL
Sbjct: 7 HVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRA 66
Query: 615 QHLEKYPDYKYKPRPKRTCLVDGKK 639
H++++PDYKY+PR K L+ K
Sbjct: 67 MHMKEHPDYKYRPRRKPKTLLKKDK 91
>gi|28195386 sex-determining region Y-box 2 [Homo sapiens]
Length = 317
Score = 101 bits (252), Expect = 2e-21
Identities = 52/121 (42%), Positives = 72/121 (59%), Gaps = 3/121 (2%)
Query: 522 MMDFNLS--GDSDGSAGVSESRIYRESRGRGSNEP-HIKRPMNAFMVWAKDERRKILQAF 578
MM+ L G S G + + G N P +KRPMNAFMVW++ +RRK+ Q
Sbjct: 4 MMETELKPPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQEN 63
Query: 579 PDMHNSNISKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGK 638
P MHNS ISK LG+ WK ++ EK+P+ +E RL H++++PDYKY+PR K L+
Sbjct: 64 PKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKD 123
Query: 639 K 639
K
Sbjct: 124 K 124
>gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens]
Length = 466
Score = 100 bits (248), Expect = 7e-21
Identities = 40/84 (47%), Positives = 59/84 (70%)
Query: 548 GRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYE 607
G ++PH+KRPMNAFMVWA+ RRK+ +P +HN+ +SK LG W+ + +K+P+ E
Sbjct: 96 GASKSKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESDKRPFIE 155
Query: 608 EQARLSKQHLEKYPDYKYKPRPKR 631
E RL QH + +PDYKY+PR ++
Sbjct: 156 EAERLRMQHKKDHPDYKYQPRRRK 179
>gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens]
Length = 446
Score = 99.4 bits (246), Expect = 1e-20
Identities = 40/80 (50%), Positives = 59/80 (73%)
Query: 553 EPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEEQARL 612
+PH+KRPMNAFMVWA+ RRK+ +P +HN+ +SK LG W+ ++ EK+P+ EE RL
Sbjct: 99 KPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERL 158
Query: 613 SKQHLEKYPDYKYKPRPKRT 632
QH + +PDYKY+PR +++
Sbjct: 159 RVQHKKDHPDYKYQPRRRKS 178
>gi|4507225 sex determining region Y [Homo sapiens]
Length = 204
Score = 98.2 bits (243), Expect = 3e-20
Identities = 43/86 (50%), Positives = 60/86 (69%)
Query: 549 RGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQPYYEE 608
+G+ + +KRPMNAF+VW++D+RRK+ P M NS ISK LG +WK +T EK P+++E
Sbjct: 53 KGNVQDRVKRPMNAFIVWSRDQRRKMALENPRMRNSEISKQLGYQWKMLTEAEKWPFFQE 112
Query: 609 QARLSKQHLEKYPDYKYKPRPKRTCL 634
+L H EKYP+YKY+PR K L
Sbjct: 113 AQKLQAMHREKYPNYKYRPRRKAKML 138
>gi|5902106 SRY-box 15 [Homo sapiens]
Length = 233
Score = 97.8 bits (242), Expect = 3e-20
Identities = 50/104 (48%), Positives = 64/104 (61%), Gaps = 7/104 (6%)
Query: 534 SAGVSESRIYRESRGRGSNEP-------HIKRPMNAFMVWAKDERRKILQAFPDMHNSNI 586
+A S S +E G GS +KRPMNAFMVW+ +RR++ Q P MHNS I
Sbjct: 20 TAAASSSSGPQEREGAGSPAAPGTLPLEKVKRPMNAFMVWSSAQRRQMAQQNPKMHNSEI 79
Query: 587 SKILGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPK 630
SK LG++WK + EK+P+ EE RL +HL YPDYKY+PR K
Sbjct: 80 SKRLGAQWKLLDEDEKRPFVEEAKRLRARHLRDYPDYKYRPRRK 123
>gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo
sapiens]
Length = 501
Score = 82.0 bits (201), Expect = 2e-15
Identities = 36/95 (37%), Positives = 60/95 (63%), Gaps = 6/95 (6%)
Query: 535 AGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRW 594
AG+ ++ ++ G H+KRPMNAFMVWA+ R + +A P +N+ IS LG W
Sbjct: 322 AGIPDTPFSKDRNG------HVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEW 375
Query: 595 KAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRP 629
++ +K+PYY+E ++ ++H E++P + Y+PRP
Sbjct: 376 NKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRP 410
>gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Homo
sapiens]
Length = 753
Score = 82.0 bits (201), Expect = 2e-15
Identities = 36/95 (37%), Positives = 60/95 (63%), Gaps = 6/95 (6%)
Query: 535 AGVSESRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRW 594
AG+ ++ ++ G H+KRPMNAFMVWA+ R + +A P +N+ IS LG W
Sbjct: 322 AGIPDTPFSKDRNG------HVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEW 375
Query: 595 KAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRP 629
++ +K+PYY+E ++ ++H E++P + Y+PRP
Sbjct: 376 NKLSEEQKKPYYDEAQKIKEKHREEFPGWVYQPRP 410
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 71.6 bits (174), Expect = 3e-12
Identities = 37/117 (31%), Positives = 62/117 (52%), Gaps = 3/117 (2%)
Query: 545 ESRGRGSNE---PHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLE 601
E GR N+ HI+RPMNAFM+++K R + Q P+ N +SKILG W A+ E
Sbjct: 186 EKDGRSPNKREKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKE 245
Query: 602 KQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQ 658
KQ Y++ ++ + H + +PD+K+ + ++ + K +G R + M +
Sbjct: 246 KQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPTSLGLAGGHKETRERSMSE 302
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 63.9 bits (154), Expect = 5e-10
Identities = 98/394 (24%), Positives = 158/394 (40%), Gaps = 84/394 (21%)
Query: 70 VSLLTQETCGHRTPTSQHNTMEVDGNKVMSSFAPHNSSTSPQKAEEGGRQSGESLSSTAL 129
V++L Q+ G P H + + ++V+SS PQ A++G G L +
Sbjct: 3807 VAVLQQQHPGALGPQGPHRQVLMTQSRVLSS---------PQLAQQGQGLMGHRLVTAQQ 3857
Query: 130 GTPERR---KGSLADVVDTLKQRKMEELIKNEPEETPSIEKLLSKDWKDKLLAMGSGNFG 186
+++ +GS+A + L+Q L+S + KL A G+
Sbjct: 3858 QQQQQQHQQQGSMAGL-SHLQQ------------------SLMSHSGQPKLSAQPMGSLQ 3898
Query: 187 EIKGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQE 246
+++ ++Q + QL ++Q L +Q++L Q+++Q+QQ +L +QQQ+
Sbjct: 3899 QLQ---------QQQQLQQQQQLQQQQQQQL---QQQQQLQQQQLQQQQQQQQLQQQQQQ 3946
Query: 247 QIARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAA---AAQQGFLLPPG 303
Q+ +QQQQL QQQ + QQ Q Q Q+ L RTL + QQ L PG
Sbjct: 3947 QLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLL------NQSRTLLSPQQQQQQQVALGPG 4000
Query: 304 FSYKAGCSDPYPVQLIPTTM-----------AAAAAATPGL-----GPLQLQQLYAAQLA 347
K P L PT + A ++ AT G GPL +
Sbjct: 4001 MPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAI----GTTPE 4056
Query: 348 AMQVSPGGKLPGIPQGNLGAAVSPTSIHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSDGK 407
+M PG P + + V P P S ++ PL L + +
Sbjct: 4057 SMATEPGEVKPSLSGDSQLLLVQP---------QPQPQPSSLQLQPPLRLPGQQQQQVSL 4107
Query: 408 SPTSPTSPHMPALRINSGAGPLKASVPAALASPS 441
T+ H ++ SG+ +SVP LA PS
Sbjct: 4108 LHTAGGGSHG---QLGSGSSSEASSVPHLLAQPS 4138
Score = 36.6 bits (83), Expect = 0.090
Identities = 26/80 (32%), Positives = 43/80 (53%), Gaps = 5/80 (6%)
Query: 222 EQKKLAASQIEKQRQQMELAKQQQEQIARQQQQLLQQQHKINLLQ-QQIQVQGQLPPLMI 280
+ + L Q++ Q+Q+M+LA++ Q+ QQQQ QQQH + + QQ Q QG
Sbjct: 3712 DSRLLQERQLQLQQQRMQLAQKLQQ----QQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQ 3767
Query: 281 PVFPPDQRTLAAAAQQGFLL 300
+ P Q + ++ QG L+
Sbjct: 3768 ALGPKPQGLMPPSSHQGLLV 3787
Score = 35.4 bits (80), Expect = 0.20
Identities = 33/137 (24%), Positives = 51/137 (37%), Gaps = 2/137 (1%)
Query: 276 PPLMIPVFPPDQRTLAAAAQQGFLLPPGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGP 335
PP P+ PP + + + + L P F P L P A+ + P P
Sbjct: 575 PPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSP 634
Query: 336 LQLQQLYAAQLAAMQVSPGGKLPGIPQGNLGAAVSPTSIHTDKSTNSPPPKSKDEVAQPL 395
+ + +VS LP + + + SP S ++S SPPP++ P
Sbjct: 635 MSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPE 694
Query: 396 NLSAKPKTSDGKSPTSP 412
+ P D SP SP
Sbjct: 695 DSPTSPPPED--SPASP 709
Score = 33.9 bits (76), Expect = 0.58
Identities = 51/188 (27%), Positives = 71/188 (37%), Gaps = 31/188 (16%)
Query: 200 RQLMGMINQLTSLREQLLAAHDEQKKLAASQI----------EKQRQQMELAKQQQEQIA 249
+QL+ M QL L EQ+ +K L A Q E ++++L +QQ +I
Sbjct: 3518 QQLLQM--QLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQ 3575
Query: 250 RQQQQLLQQQHK-INLL---------QQQIQVQGQLPPLMIPVFPPDQRTLAAAAQQGFL 299
+Q Q+ +QQ + NL+ QQQ Q Q Q + P Q G L
Sbjct: 3576 KQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQL 3635
Query: 300 LP-PGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGPL-------QLQQLYAAQLAAMQV 351
LP G G L T A PG GP Q QQ ++ ++
Sbjct: 3636 LPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPG-GPFLNTALAQQQQQQHSGGAGSLAG 3694
Query: 352 SPGGKLPG 359
GG PG
Sbjct: 3695 PSGGFFPG 3702
Score = 32.7 bits (73), Expect = 1.3
Identities = 48/184 (26%), Positives = 68/184 (36%), Gaps = 48/184 (26%)
Query: 277 PLMIPVFPPDQRTLAAAAQQGFLLPPGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGPL 336
P +P+ P + +L+ L+PP DP P L P AAA P L P
Sbjct: 912 PEELPLSPSGEPSLSPQ-----LMPP---------DPLPPPLSP---IITAAAPPALSP- 953
Query: 337 QLQQLYAAQLAAMQVSPGGKLPGIPQGNLGAAVSPTSIHTDKSTNSPPPKSK---DEVAQ 393
L ++ G K P+ L A + T I SPPP++ E
Sbjct: 954 ---------LGELEYPFGAKGDSDPESPLAAPILETPI-------SPPPEANCTDPEPVP 997
Query: 394 PLNLSAKPKTSDGKSPTSP---------TSPHMPALRINSGAGPLKASVPAALASPSARV 444
P+ L P + G P SP SP + + + P + S PA S + +
Sbjct: 998 PMILPPSPGSPVG--PASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPL 1055
Query: 445 STIG 448
S IG
Sbjct: 1056 SPIG 1059
Score = 30.4 bits (67), Expect = 6.4
Identities = 41/169 (24%), Positives = 55/169 (32%), Gaps = 22/169 (13%)
Query: 248 IARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAAQQGFLLPPGFSYK 307
+ +QQQQL QQQ + + + P P A L PG
Sbjct: 2810 LQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVP 2869
Query: 308 AGCSDPYPVQL---IPTTMAAAAAATPGLGPLQLQQLYAAQLAAMQVSPGGKLPGIPQGN 364
++L + + PG GP Q + Y +++ P+G
Sbjct: 2870 GPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLA--------PEGL 2921
Query: 365 LGAAVSPTSIHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSDGKSPTSPT 413
G AVS PP K A LN S P T K PT PT
Sbjct: 2922 RGLAVS----------GLPPQKPSAPPAPELNNSLHP-TPHTKGPTLPT 2959
Score = 30.4 bits (67), Expect = 6.4
Identities = 17/56 (30%), Positives = 29/56 (51%)
Query: 192 PESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMELAKQQQEQ 247
PE+ AEK + + +++ +Q+ E L A KQ+QQ + +QQQ+Q
Sbjct: 3557 PEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQ 3612
>gi|195222734 lymphoid enhancer-binding factor 1 isoform 3 [Homo
sapiens]
Length = 386
Score = 63.2 bits (152), Expect = 9e-10
Identities = 34/139 (24%), Positives = 70/139 (50%), Gaps = 16/139 (11%)
Query: 543 YRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEK 602
+ + + + PHIK+P+NAFM++ K+ R ++ ++ I++ILG RW A++ E+
Sbjct: 258 HEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQ 317
Query: 603 QPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNV 662
YYE + + H++ YP + + GKK + +R+++++ +
Sbjct: 318 AKYYELARKERQLHMQLYPGWSARDN-------YGKK---------KKRKREKLQESASG 361
Query: 663 GQQAQIPIATAGVVYPGAI 681
G+++ P A PG +
Sbjct: 362 GKRSSFPTCKAKAATPGPL 380
>gi|226371764 transcription factor 7-like 2 isoform 1 [Homo sapiens]
Length = 602
Score = 60.8 bits (146), Expect = 4e-09
Identities = 30/94 (31%), Positives = 54/94 (57%), Gaps = 1/94 (1%)
Query: 531 SDGSAGVSESRIYRESRGRGSNE-PHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKI 589
S G S +++S+ + PHIK+P+NAFM++ K+ R K++ ++ I++I
Sbjct: 324 SQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQI 383
Query: 590 LGSRWKAMTNLEKQPYYEEQARLSKQHLEKYPDY 623
LG RW A++ E+ YYE + + H++ YP +
Sbjct: 384 LGRRWHALSREEQAKYYELARKERQLHMQLYPGW 417
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.127 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,252,667
Number of Sequences: 37866
Number of extensions: 1695100
Number of successful extensions: 16226
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 288
Number of HSP's successfully gapped in prelim test: 552
Number of HSP's that attempted gapping in prelim test: 9514
Number of HSP's gapped (non-prelim): 3841
length of query: 763
length of database: 18,247,518
effective HSP length: 110
effective length of query: 653
effective length of database: 14,082,258
effective search space: 9195714474
effective search space used: 9195714474
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.