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Search of human proteins with 226530313
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|226530313 microtubule associated monoxygenase, calponin and
LIM domain containing 1 isoform 2 [Homo sapiens]
(981 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|226530313 microtubule associated monoxygenase, calponin and L... 1981 0.0
gi|205360947 microtubule associated monoxygenase, calponin and L... 1353 0.0
gi|170172518 microtubule associated monoxygenase, calponin and L... 388 e-107
gi|209862793 microtubule associated monoxygenase, calponin and L... 388 e-107
gi|209862789 microtubule associated monoxygenase, calponin and L... 388 e-107
gi|7662284 microtubule associated monoxygenase, calponin and LIM... 353 4e-97
gi|31324577 molecule interacting with Rab13 [Homo sapiens] 138 2e-32
gi|33667117 MICAL-like 2 isoform 1 [Homo sapiens] 130 6e-30
gi|118918413 MICAL C-terminal like [Homo sapiens] 119 1e-26
gi|67782321 spectrin beta isoform a [Homo sapiens] 77 1e-13
gi|67782319 spectrin beta isoform b [Homo sapiens] 77 1e-13
gi|170016061 spectrin, beta, non-erythrocytic 5 [Homo sapiens] 74 5e-13
gi|150378549 tangerin [Homo sapiens] 74 9e-13
gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens] 72 2e-12
gi|4557241 actinin, alpha 3 [Homo sapiens] 71 4e-12
gi|4501893 actinin, alpha 2 [Homo sapiens] 71 4e-12
gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [... 70 1e-11
gi|194097352 actinin, alpha 1 isoform c [Homo sapiens] 69 2e-11
gi|194097350 actinin, alpha 1 isoform a [Homo sapiens] 69 2e-11
gi|4501891 actinin, alpha 1 isoform b [Homo sapiens] 69 2e-11
gi|33188445 microfilament and actin filament cross-linker protei... 68 4e-11
gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo ... 67 6e-11
gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo ... 67 6e-11
gi|12025678 actinin, alpha 4 [Homo sapiens] 67 1e-10
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof... 66 1e-10
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof... 66 1e-10
gi|116517305 cysteine-rich protein 3 [Homo sapiens] 62 2e-09
gi|224451082 cytospin A [Homo sapiens] 60 1e-08
gi|224451080 cytospin A [Homo sapiens] 60 1e-08
gi|169218211 PREDICTED: similar to plectin 1, partial [Homo sapi... 60 1e-08
>gi|226530313 microtubule associated monoxygenase, calponin and LIM
domain containing 1 isoform 2 [Homo sapiens]
Length = 981
Score = 1981 bits (5132), Expect = 0.0
Identities = 981/981 (100%), Positives = 981/981 (100%)
Query: 1 MASPTSTNPAHAHFESFLQAQLCQDVLSSFQELCGALGLEPGGGLPQYHKIKDQLNYWSA 60
MASPTSTNPAHAHFESFLQAQLCQDVLSSFQELCGALGLEPGGGLPQYHKIKDQLNYWSA
Sbjct: 1 MASPTSTNPAHAHFESFLQAQLCQDVLSSFQELCGALGLEPGGGLPQYHKIKDQLNYWSA 60
Query: 61 KSLWTKLDKRAGQPVYQQGRACTSTKCLVVGAGPCGLRVAVELALLGARVVLVEKRTKFS 120
KSLWTKLDKRAGQPVYQQGRACTSTKCLVVGAGPCGLRVAVELALLGARVVLVEKRTKFS
Sbjct: 61 KSLWTKLDKRAGQPVYQQGRACTSTKCLVVGAGPCGLRVAVELALLGARVVLVEKRTKFS 120
Query: 121 RHNVLHLWPFTIHDLRALGAKKFYGRFCTGTLDHISIRQLQLLLLKVALLLGVEIHWGVT 180
RHNVLHLWPFTIHDLRALGAKKFYGRFCTGTLDHISIRQLQLLLLKVALLLGVEIHWGVT
Sbjct: 121 RHNVLHLWPFTIHDLRALGAKKFYGRFCTGTLDHISIRQLQLLLLKVALLLGVEIHWGVT 180
Query: 181 FTGLQPPPRKGSGWRAQLQPNPPAQLANYEFDVLISAAGGKFVPEGFKVREMRGKLAIGI 240
FTGLQPPPRKGSGWRAQLQPNPPAQLANYEFDVLISAAGGKFVPEGFKVREMRGKLAIGI
Sbjct: 181 FTGLQPPPRKGSGWRAQLQPNPPAQLANYEFDVLISAAGGKFVPEGFKVREMRGKLAIGI 240
Query: 241 TANFVNGRTVEETQVPEISGVARIYNQSFFQSLLKATGIDLENIVYYKDDTHYFVMTAKK 300
TANFVNGRTVEETQVPEISGVARIYNQSFFQSLLKATGIDLENIVYYKDDTHYFVMTAKK
Sbjct: 241 TANFVNGRTVEETQVPEISGVARIYNQSFFQSLLKATGIDLENIVYYKDDTHYFVMTAKK 300
Query: 301 QCLLRLGVLRQPFWPLGTGVARGFLAAFDAAWMVKRWAEGAESLEVLAERESLYQLLSQT 360
QCLLRLGVLRQPFWPLGTGVARGFLAAFDAAWMVKRWAEGAESLEVLAERESLYQLLSQT
Sbjct: 301 QCLLRLGVLRQPFWPLGTGVARGFLAAFDAAWMVKRWAEGAESLEVLAERESLYQLLSQT 360
Query: 361 SPENMHRNVAQYGLDPATRYPNLNLRAVTPNQVRDLYDVLAKEPVQRNNDKTDTGMPATG 420
SPENMHRNVAQYGLDPATRYPNLNLRAVTPNQVRDLYDVLAKEPVQRNNDKTDTGMPATG
Sbjct: 361 SPENMHRNVAQYGLDPATRYPNLNLRAVTPNQVRDLYDVLAKEPVQRNNDKTDTGMPATG 420
Query: 421 SAGTQEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGAL 480
SAGTQEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGAL
Sbjct: 421 SAGTQEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGAL 480
Query: 481 EATAWALKVAENELGITPVVSAQAVVAGSDPLGLIAYLSHFHSAFKSMAHSPGPVSQASP 540
EATAWALKVAENELGITPVVSAQAVVAGSDPLGLIAYLSHFHSAFKSMAHSPGPVSQASP
Sbjct: 481 EATAWALKVAENELGITPVVSAQAVVAGSDPLGLIAYLSHFHSAFKSMAHSPGPVSQASP 540
Query: 541 GTSSAVLFLSKLQRTLQRSRAKENAEDAGGKKLRLEMEAETPSTEVPPDPEPGVPLTPPS 600
GTSSAVLFLSKLQRTLQRSRAKENAEDAGGKKLRLEMEAETPSTEVPPDPEPGVPLTPPS
Sbjct: 541 GTSSAVLFLSKLQRTLQRSRAKENAEDAGGKKLRLEMEAETPSTEVPPDPEPGVPLTPPS 600
Query: 601 QHQEAGAGDLCALCGEHLYVLERLCVNGHFFHRSCFRCHTCEATLWPGGYEQHPGDGHFY 660
QHQEAGAGDLCALCGEHLYVLERLCVNGHFFHRSCFRCHTCEATLWPGGYEQHPGDGHFY
Sbjct: 601 QHQEAGAGDLCALCGEHLYVLERLCVNGHFFHRSCFRCHTCEATLWPGGYEQHPGDGHFY 660
Query: 661 CLQHLPQTDHKAEGSDRGPESPELPTPSENSMPPGLSTPTASQEGAGPVPDPSQPTRRQI 720
CLQHLPQTDHKAEGSDRGPESPELPTPSENSMPPGLSTPTASQEGAGPVPDPSQPTRRQI
Sbjct: 661 CLQHLPQTDHKAEGSDRGPESPELPTPSENSMPPGLSTPTASQEGAGPVPDPSQPTRRQI 720
Query: 721 RLSSPERQRLSSLNLTPDPEMEPPPKPPRSCSALARHALESSFVGWGLPVQSPQALVAME 780
RLSSPERQRLSSLNLTPDPEMEPPPKPPRSCSALARHALESSFVGWGLPVQSPQALVAME
Sbjct: 721 RLSSPERQRLSSLNLTPDPEMEPPPKPPRSCSALARHALESSFVGWGLPVQSPQALVAME 780
Query: 781 KEEKESPFSSEEEEEDVPLDSDVEQALQTFAKTSGTMNNYPTWRRTLLRRAKEEEMKRFC 840
KEEKESPFSSEEEEEDVPLDSDVEQALQTFAKTSGTMNNYPTWRRTLLRRAKEEEMKRFC
Sbjct: 781 KEEKESPFSSEEEEEDVPLDSDVEQALQTFAKTSGTMNNYPTWRRTLLRRAKEEEMKRFC 840
Query: 841 KAQTIQRRLNEIEAALRELEAEGVKLELALRRQSSSPEQQKKLWVGQLLQLVDKKNSLVA 900
KAQTIQRRLNEIEAALRELEAEGVKLELALRRQSSSPEQQKKLWVGQLLQLVDKKNSLVA
Sbjct: 841 KAQTIQRRLNEIEAALRELEAEGVKLELALRRQSSSPEQQKKLWVGQLLQLVDKKNSLVA 900
Query: 901 EEAELMITVQELNLEEKQWQLDQELRGYMNREENLKTAADRQAEDQVLRKLVDLVNQRDA 960
EEAELMITVQELNLEEKQWQLDQELRGYMNREENLKTAADRQAEDQVLRKLVDLVNQRDA
Sbjct: 901 EEAELMITVQELNLEEKQWQLDQELRGYMNREENLKTAADRQAEDQVLRKLVDLVNQRDA 960
Query: 961 LIRFQEERRLSELALGTGAQG 981
LIRFQEERRLSELALGTGAQG
Sbjct: 961 LIRFQEERRLSELALGTGAQG 981
>gi|205360947 microtubule associated monoxygenase, calponin and LIM
domain containing 1 isoform 1 [Homo sapiens]
Length = 1067
Score = 1353 bits (3502), Expect = 0.0
Identities = 671/673 (99%), Positives = 672/673 (99%)
Query: 309 LRQPFWPLGTGVARGFLAAFDAAWMVKRWAEGAESLEVLAERESLYQLLSQTSPENMHRN 368
L +PFWPLGTGVARGFLAAFDAAWMVKRWAEGAESLEVLAERESLYQLLSQTSPENMHRN
Sbjct: 395 LVEPFWPLGTGVARGFLAAFDAAWMVKRWAEGAESLEVLAERESLYQLLSQTSPENMHRN 454
Query: 369 VAQYGLDPATRYPNLNLRAVTPNQVRDLYDVLAKEPVQRNNDKTDTGMPATGSAGTQEEL 428
VAQYGLDPATRYPNLNLRAVTPNQVRDLYDVLAKEPVQRNNDKTDTGMPATGSAGTQEEL
Sbjct: 455 VAQYGLDPATRYPNLNLRAVTPNQVRDLYDVLAKEPVQRNNDKTDTGMPATGSAGTQEEL 514
Query: 429 LRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATAWALK 488
LRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATAWALK
Sbjct: 515 LRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATAWALK 574
Query: 489 VAENELGITPVVSAQAVVAGSDPLGLIAYLSHFHSAFKSMAHSPGPVSQASPGTSSAVLF 548
VAENELGITPVVSAQAVVAGSDPLGLIAYLSHFHSAFKSMAHSPGPVSQASPGTSSAVLF
Sbjct: 575 VAENELGITPVVSAQAVVAGSDPLGLIAYLSHFHSAFKSMAHSPGPVSQASPGTSSAVLF 634
Query: 549 LSKLQRTLQRSRAKENAEDAGGKKLRLEMEAETPSTEVPPDPEPGVPLTPPSQHQEAGAG 608
LSKLQRTLQRSRAKENAEDAGGKKLRLEMEAETPSTEVPPDPEPGVPLTPPSQHQEAGAG
Sbjct: 635 LSKLQRTLQRSRAKENAEDAGGKKLRLEMEAETPSTEVPPDPEPGVPLTPPSQHQEAGAG 694
Query: 609 DLCALCGEHLYVLERLCVNGHFFHRSCFRCHTCEATLWPGGYEQHPGDGHFYCLQHLPQT 668
DLCALCGEHLYVLERLCVNGHFFHRSCFRCHTCEATLWPGGYEQHPGDGHFYCLQHLPQT
Sbjct: 695 DLCALCGEHLYVLERLCVNGHFFHRSCFRCHTCEATLWPGGYEQHPGDGHFYCLQHLPQT 754
Query: 669 DHKAEGSDRGPESPELPTPSENSMPPGLSTPTASQEGAGPVPDPSQPTRRQIRLSSPERQ 728
DHKAEGSDRGPESPELPTPSENSMPPGLSTPTASQEGAGPVPDPSQPTRRQIRLSSPERQ
Sbjct: 755 DHKAEGSDRGPESPELPTPSENSMPPGLSTPTASQEGAGPVPDPSQPTRRQIRLSSPERQ 814
Query: 729 RLSSLNLTPDPEMEPPPKPPRSCSALARHALESSFVGWGLPVQSPQALVAMEKEEKESPF 788
RLSSLNLTPDPEMEPPPKPPRSCSALARHALESSFVGWGLPVQSPQALVAMEKEEKESPF
Sbjct: 815 RLSSLNLTPDPEMEPPPKPPRSCSALARHALESSFVGWGLPVQSPQALVAMEKEEKESPF 874
Query: 789 SSEEEEEDVPLDSDVEQALQTFAKTSGTMNNYPTWRRTLLRRAKEEEMKRFCKAQTIQRR 848
SSEEEEEDVPLDSDVEQALQTFAKTSGTMNNYPTWRRTLLRRAKEEEMKRFCKAQTIQRR
Sbjct: 875 SSEEEEEDVPLDSDVEQALQTFAKTSGTMNNYPTWRRTLLRRAKEEEMKRFCKAQTIQRR 934
Query: 849 LNEIEAALRELEAEGVKLELALRRQSSSPEQQKKLWVGQLLQLVDKKNSLVAEEAELMIT 908
LNEIEAALRELEAEGVKLELALRRQSSSPEQQKKLWVGQLLQLVDKKNSLVAEEAELMIT
Sbjct: 935 LNEIEAALRELEAEGVKLELALRRQSSSPEQQKKLWVGQLLQLVDKKNSLVAEEAELMIT 994
Query: 909 VQELNLEEKQWQLDQELRGYMNREENLKTAADRQAEDQVLRKLVDLVNQRDALIRFQEER 968
VQELNLEEKQWQLDQELRGYMNREENLKTAADRQAEDQVLRKLVDLVNQRDALIRFQEER
Sbjct: 995 VQELNLEEKQWQLDQELRGYMNREENLKTAADRQAEDQVLRKLVDLVNQRDALIRFQEER 1054
Query: 969 RLSELALGTGAQG 981
RLSELALGTGAQG
Sbjct: 1055 RLSELALGTGAQG 1067
Score = 635 bits (1638), Expect = 0.0
Identities = 313/315 (99%), Positives = 313/315 (99%), Gaps = 1/315 (0%)
Query: 1 MASPTSTNPAHAHFESFLQAQLCQDVLSSFQELCGALGLEPGGGLPQYHKIKDQLNYWSA 60
MASPTSTNPAHAHFESFLQAQLCQDVLSSFQELCGALGLEPGGGLPQYHKIKDQLNYWSA
Sbjct: 1 MASPTSTNPAHAHFESFLQAQLCQDVLSSFQELCGALGLEPGGGLPQYHKIKDQLNYWSA 60
Query: 61 KSLWTKLDKRAGQPVYQQGRACTSTKCLVVGAGPCGLRVAVELALLGARVVLVEKRTKFS 120
KSLWTKLDKRAGQPVYQQGRACTSTKCLVVGAGPCGLRVAVELALLGARVVLVEKRTKFS
Sbjct: 61 KSLWTKLDKRAGQPVYQQGRACTSTKCLVVGAGPCGLRVAVELALLGARVVLVEKRTKFS 120
Query: 121 RHNVLHLWPFTIHDLRALGAKKFYGRFCTGTLDHISIRQLQLLLLKVALLLGVEIHWGVT 180
RHNVLHLWPFTIHDLRALGAKKFYGRFCTGTLDHISIRQLQLLLLKVALLLGVEIHWGVT
Sbjct: 121 RHNVLHLWPFTIHDLRALGAKKFYGRFCTGTLDHISIRQLQLLLLKVALLLGVEIHWGVT 180
Query: 181 FTGLQPPPRKGSGWRAQLQPNPPAQLANYEFDVLISAAGGKFVPEGFKVREMRGKLAIGI 240
FTGLQPPPRKGSGWRAQLQPNPPAQLANYEFDVLISAAGGKFVPEGFKVREMRGKLAIGI
Sbjct: 181 FTGLQPPPRKGSGWRAQLQPNPPAQLANYEFDVLISAAGGKFVPEGFKVREMRGKLAIGI 240
Query: 241 TANFVNGRTVEETQVPEISGVARIYNQSFFQSLLKATGIDLENIVYYKDDTHYFVMTAKK 300
TANFVNGRTVEETQVPEISGVARIYNQSFFQSLLKATGIDLENIVYYKDDTHYFVMTAKK
Sbjct: 241 TANFVNGRTVEETQVPEISGVARIYNQSFFQSLLKATGIDLENIVYYKDDTHYFVMTAKK 300
Query: 301 QCLLRLGVLRQPFWP 315
QCLLRLGVLRQ WP
Sbjct: 301 QCLLRLGVLRQD-WP 314
>gi|170172518 microtubule associated monoxygenase, calponin and LIM
domain containing 3 isoform 3 [Homo sapiens]
Length = 966
Score = 388 bits (996), Expect = e-107
Identities = 191/306 (62%), Positives = 231/306 (75%), Gaps = 5/306 (1%)
Query: 8 NPAHAHFESFLQAQLCQDVLSSFQELCGALGLEPGGGLPQYHKIKDQLNYWSAKSLWTKL 67
NPAH F+ F+QA C+ L +FQELC L L+P YHK+K +LNYW AK+LW KL
Sbjct: 10 NPAHVLFDRFVQATTCKGTLKAFQELCDHLELKPKDYRSFYHKLKSKLNYWKAKALWAKL 69
Query: 68 DKRAGQPVYQQGRACTSTKCLVVGAGPCGLRVAVELALLGARVVLVEKRTKFSRHNVLHL 127
DKR Y++G+ACT+TKCL++GAGPCGLR A++L+LLGA+VV++EKR FSR+NVLHL
Sbjct: 70 DKRGSHKDYKKGKACTNTKCLIIGAGPCGLRTAIDLSLLGAKVVVIEKRDAFSRNNVLHL 129
Query: 128 WPFTIHDLRALGAKKFYGRFCTGTLDHISIRQLQLLLLKVALLLGVEIHWGVTFTGLQPP 187
WPFTIHDLR LGAKKFYG+FC G +DHISIRQLQL+LLKVAL+LG+EIH V F GL P
Sbjct: 130 WPFTIHDLRGLGAKKFYGKFCAGAIDHISIRQLQLILLKVALILGIEIHVNVEFQGLIQP 189
Query: 188 P----RKGSGWRAQLQPNPPAQLANYEFDVLISAAGGKFVPEGFKVREMRGKLAIGITAN 243
P + GWRA + P ++ YEF+V+I G + EGF+ +E RGKLAI ITAN
Sbjct: 190 PEDQENERIGWRALVHPK-THPVSEYEFEVIIGGDGRRNTLEGFRRKEFRGKLAIAITAN 248
Query: 244 FVNGRTVEETQVPEISGVARIYNQSFFQSLLKATGIDLENIVYYKDDTHYFVMTAKKQCL 303
F+N T E +V EISGVA I+NQ FFQ L +ATGIDLENIVYYKDDTHYFVMTAKKQ L
Sbjct: 249 FINRNTTAEAKVEEISGVAFIFNQKFFQELREATGIDLENIVYYKDDTHYFVMTAKKQSL 308
Query: 304 LRLGVL 309
L GV+
Sbjct: 309 LDKGVI 314
Score = 266 bits (681), Expect = 5e-71
Identities = 169/501 (33%), Positives = 238/501 (47%), Gaps = 74/501 (14%)
Query: 309 LRQPFWPLGTGVARGFLAAFDAAWMVKRWAEGAESLEVLAERESLYQLLSQTSPENMHRN 368
L +PFWP+GTG+ARGFLAA D+AWMV+ W+ G LEVLAERES+Y+LL QT+PEN+ +N
Sbjct: 400 LLEPFWPMGTGIARGFLAAMDSAWMVRSWSLGTSPLEVLAERESIYRLLPQTTPENVSKN 459
Query: 369 VAQYGLDPATRYPNLNLRAVTPNQVRDLYDVLAKEPVQRN-----NDKTDTGMPATGSAG 423
+QY +DP TRYPN+N+ + P+QVR LYD + + N +T + S
Sbjct: 460 FSQYSIDPVTRYPNINVNFLRPSQVRHLYDTGETKDIHLEMESLVNSRTTPKLTRNESVA 519
Query: 424 TQEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEAT 483
+LL WCQ QT GY GV+V+DL+ SW GLALCA+++R +P L++ L +
Sbjct: 520 RSSKLLGWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNVEKNN 579
Query: 484 AWALKVAENELGITPVVSAQ--AVVAGSDPLGLIAYLSHFHSAFKSMAHSPGPVSQAS-- 539
A +AE ELGI+P+++ + A V D L ++ YL+ F+ FK S + +
Sbjct: 580 QLAFDIAEKELGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMFKDSLPSSDTLDLNAEE 639
Query: 540 -----PGTSSAVLFLSKLQRTLQRSRA----KENAEDAGGKKLRLEMEAETPSTEVPPDP 590
T S + FLSKL +T+ R R+ KE D GK+ + E +
Sbjct: 640 KAVLIASTRSPISFLSKLGQTISRKRSPKDKKEKDLDGAGKRRKTSQSEEEEAPRGHRGE 699
Query: 591 EPGVPLT------------------------------PPSQH--------------QEAG 606
P + T P+Q Q G
Sbjct: 700 RPTLVSTLTDRRMDVAVGNQNKVKYMATQLLAKFEENAPAQSIGIRRQGSMKKEFPQNLG 759
Query: 607 AGDLCALCGEHLYVLERLCVNGHFFHRSCFRCHTCEATLWPGGYEQHPGDGHFYCLQH-- 664
D C C + +YV+ERL G FFHRSCF+C C TL Y DG FYC H
Sbjct: 760 GSDTCYFCQKRVYVMERLSAEGKFFHRSCFKCEYCATTLRLSAYAYDIEDGKFYCKPHYC 819
Query: 665 -----LPQTDHKAEGSDRGPES----PELPTPSENSMPPGLSTPTASQEGAGPVPDPSQP 715
Q A G E+ + T N +++ T G+G V +P
Sbjct: 820 YRLSGYAQRKRPAVAPLSGKEAKGPLQDGATTDANGRANAVASSTERTPGSG-VNGLEEP 878
Query: 716 TRRQIRLSSPERQRLSSLNLT 736
+ + +PER L + L+
Sbjct: 879 SIAKRLRGTPERIELENYRLS 899
>gi|209862793 microtubule associated monoxygenase, calponin and LIM
domain containing 3 isoform 2 [Homo sapiens]
Length = 1073
Score = 388 bits (996), Expect = e-107
Identities = 191/306 (62%), Positives = 231/306 (75%), Gaps = 5/306 (1%)
Query: 8 NPAHAHFESFLQAQLCQDVLSSFQELCGALGLEPGGGLPQYHKIKDQLNYWSAKSLWTKL 67
NPAH F+ F+QA C+ L +FQELC L L+P YHK+K +LNYW AK+LW KL
Sbjct: 10 NPAHVLFDRFVQATTCKGTLKAFQELCDHLELKPKDYRSFYHKLKSKLNYWKAKALWAKL 69
Query: 68 DKRAGQPVYQQGRACTSTKCLVVGAGPCGLRVAVELALLGARVVLVEKRTKFSRHNVLHL 127
DKR Y++G+ACT+TKCL++GAGPCGLR A++L+LLGA+VV++EKR FSR+NVLHL
Sbjct: 70 DKRGSHKDYKKGKACTNTKCLIIGAGPCGLRTAIDLSLLGAKVVVIEKRDAFSRNNVLHL 129
Query: 128 WPFTIHDLRALGAKKFYGRFCTGTLDHISIRQLQLLLLKVALLLGVEIHWGVTFTGLQPP 187
WPFTIHDLR LGAKKFYG+FC G +DHISIRQLQL+LLKVAL+LG+EIH V F GL P
Sbjct: 130 WPFTIHDLRGLGAKKFYGKFCAGAIDHISIRQLQLILLKVALILGIEIHVNVEFQGLIQP 189
Query: 188 P----RKGSGWRAQLQPNPPAQLANYEFDVLISAAGGKFVPEGFKVREMRGKLAIGITAN 243
P + GWRA + P ++ YEF+V+I G + EGF+ +E RGKLAI ITAN
Sbjct: 190 PEDQENERIGWRALVHPK-THPVSEYEFEVIIGGDGRRNTLEGFRRKEFRGKLAIAITAN 248
Query: 244 FVNGRTVEETQVPEISGVARIYNQSFFQSLLKATGIDLENIVYYKDDTHYFVMTAKKQCL 303
F+N T E +V EISGVA I+NQ FFQ L +ATGIDLENIVYYKDDTHYFVMTAKKQ L
Sbjct: 249 FINRNTTAEAKVEEISGVAFIFNQKFFQELREATGIDLENIVYYKDDTHYFVMTAKKQSL 308
Query: 304 LRLGVL 309
L GV+
Sbjct: 309 LDKGVI 314
Score = 227 bits (578), Expect = 5e-59
Identities = 123/319 (38%), Positives = 178/319 (55%), Gaps = 18/319 (5%)
Query: 309 LRQPFWPLGTGVARGFLAAFDAAWMVKRWAEGAESLEVLAERESLYQLLSQTSPENMHRN 368
L +PFWP+GTG+ARGFLAA D+AWMV+ W+ G LEVLAERES+Y+LL QT+PEN+ +N
Sbjct: 400 LLEPFWPMGTGIARGFLAAMDSAWMVRSWSLGTSPLEVLAERESIYRLLPQTTPENVSKN 459
Query: 369 VAQYGLDPATRYPNLNLRAVTPNQVRDLYDVLAKEPVQRN-----NDKTDTGMPATGSAG 423
+QY +DP TRYPN+N+ + P+QVR LYD + + N +T + S
Sbjct: 460 FSQYSIDPVTRYPNINVNFLRPSQVRHLYDTGETKDIHLEMESLVNSRTTPKLTRNESVA 519
Query: 424 TQEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEAT 483
+LL WCQ QT GY GV+V+DL+ SW GLALCA+++R +P L++ L +
Sbjct: 520 RSSKLLGWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNVEKNN 579
Query: 484 AWALKVAENELGITPVVSAQ--AVVAGSDPLGLIAYLSHFHSAFKSMAHSPGPVSQAS-- 539
A +AE ELGI+P+++ + A V D L ++ YL+ F+ FK S + +
Sbjct: 580 QLAFDIAEKELGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMFKDSLPSSDTLDLNAEE 639
Query: 540 -----PGTSSAVLFLSKLQRTLQRSRA----KENAEDAGGKKLRLEMEAETPSTEVPPDP 590
T S + FLSKL +T+ R R+ KE D GK+ + E +
Sbjct: 640 KAVLIASTRSPISFLSKLGQTISRKRSPKDKKEKDLDGAGKRRKTSQSEEEEAPRGHRGE 699
Query: 591 EPGVPLTPPSQHQEAGAGD 609
P + T + + G+
Sbjct: 700 RPTLVSTLTDRRMDVAVGN 718
Score = 67.4 bits (163), Expect = 6e-11
Identities = 29/62 (46%), Positives = 33/62 (53%)
Query: 603 QEAGAGDLCALCGEHLYVLERLCVNGHFFHRSCFRCHTCEATLWPGGYEQHPGDGHFYCL 662
Q G D C C + +YV+ERL G FFHRSCF+C C TL Y DG FYC
Sbjct: 880 QNLGGSDTCYFCQKRVYVMERLSAEGKFFHRSCFKCEYCATTLRLSAYAYDIEDGKFYCK 939
Query: 663 QH 664
H
Sbjct: 940 PH 941
>gi|209862789 microtubule associated monoxygenase, calponin and LIM
domain containing 3 isoform 1 [Homo sapiens]
Length = 2002
Score = 388 bits (996), Expect = e-107
Identities = 191/306 (62%), Positives = 231/306 (75%), Gaps = 5/306 (1%)
Query: 8 NPAHAHFESFLQAQLCQDVLSSFQELCGALGLEPGGGLPQYHKIKDQLNYWSAKSLWTKL 67
NPAH F+ F+QA C+ L +FQELC L L+P YHK+K +LNYW AK+LW KL
Sbjct: 10 NPAHVLFDRFVQATTCKGTLKAFQELCDHLELKPKDYRSFYHKLKSKLNYWKAKALWAKL 69
Query: 68 DKRAGQPVYQQGRACTSTKCLVVGAGPCGLRVAVELALLGARVVLVEKRTKFSRHNVLHL 127
DKR Y++G+ACT+TKCL++GAGPCGLR A++L+LLGA+VV++EKR FSR+NVLHL
Sbjct: 70 DKRGSHKDYKKGKACTNTKCLIIGAGPCGLRTAIDLSLLGAKVVVIEKRDAFSRNNVLHL 129
Query: 128 WPFTIHDLRALGAKKFYGRFCTGTLDHISIRQLQLLLLKVALLLGVEIHWGVTFTGLQPP 187
WPFTIHDLR LGAKKFYG+FC G +DHISIRQLQL+LLKVAL+LG+EIH V F GL P
Sbjct: 130 WPFTIHDLRGLGAKKFYGKFCAGAIDHISIRQLQLILLKVALILGIEIHVNVEFQGLIQP 189
Query: 188 P----RKGSGWRAQLQPNPPAQLANYEFDVLISAAGGKFVPEGFKVREMRGKLAIGITAN 243
P + GWRA + P ++ YEF+V+I G + EGF+ +E RGKLAI ITAN
Sbjct: 190 PEDQENERIGWRALVHPK-THPVSEYEFEVIIGGDGRRNTLEGFRRKEFRGKLAIAITAN 248
Query: 244 FVNGRTVEETQVPEISGVARIYNQSFFQSLLKATGIDLENIVYYKDDTHYFVMTAKKQCL 303
F+N T E +V EISGVA I+NQ FFQ L +ATGIDLENIVYYKDDTHYFVMTAKKQ L
Sbjct: 249 FINRNTTAEAKVEEISGVAFIFNQKFFQELREATGIDLENIVYYKDDTHYFVMTAKKQSL 308
Query: 304 LRLGVL 309
L GV+
Sbjct: 309 LDKGVI 314
Score = 270 bits (691), Expect = 4e-72
Identities = 186/563 (33%), Positives = 262/563 (46%), Gaps = 87/563 (15%)
Query: 309 LRQPFWPLGTGVARGFLAAFDAAWMVKRWAEGAESLEVLAERESLYQLLSQTSPENMHRN 368
L +PFWP+GTG+ARGFLAA D+AWMV+ W+ G LEVLAERES+Y+LL QT+PEN+ +N
Sbjct: 400 LLEPFWPMGTGIARGFLAAMDSAWMVRSWSLGTSPLEVLAERESIYRLLPQTTPENVSKN 459
Query: 369 VAQYGLDPATRYPNLNLRAVTPNQVRDLYDVLAKEPVQRN-----NDKTDTGMPATGSAG 423
+QY +DP TRYPN+N+ + P+QVR LYD + + N +T + S
Sbjct: 460 FSQYSIDPVTRYPNINVNFLRPSQVRHLYDTGETKDIHLEMESLVNSRTTPKLTRNESVA 519
Query: 424 TQEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEAT 483
+LL WCQ QT GY GV+V+DL+ SW GLALCA+++R +P L++ L +
Sbjct: 520 RSSKLLGWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNVEKNN 579
Query: 484 AWALKVAENELGITPVVSAQ--AVVAGSDPLGLIAYLSHFHSAFKSMAHSPGPVSQAS-- 539
A +AE ELGI+P+++ + A V D L ++ YL+ F+ FK S + +
Sbjct: 580 QLAFDIAEKELGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMFKDSLPSSDTLDLNAEE 639
Query: 540 -----PGTSSAVLFLSKLQRTLQRSRA----KENAEDAGGKKLRLEMEAETPSTEVPPDP 590
T S + FLSKL +T+ R R+ KE D GK+ + E +
Sbjct: 640 KAVLIASTRSPISFLSKLGQTISRKRSPKDKKEKDLDGAGKRRKTSQSEEEEAPRGHRGE 699
Query: 591 EPGVPLT------------------------------PPSQH--------------QEAG 606
P + T P+Q Q G
Sbjct: 700 RPTLVSTLTDRRMDVAVGNQNKVKYMATQLLAKFEENAPAQSIGIRRQGSMKKEFPQNLG 759
Query: 607 AGDLCALCGEHLYVLERLCVNGHFFHRSCFRCHTCEATLWPGGYEQHPGDGHFYCLQH-- 664
D C C + +YV+ERL G FFHRSCF+C C TL Y DG FYC H
Sbjct: 760 GSDTCYFCQKRVYVMERLSAEGKFFHRSCFKCEYCATTLRLSAYAYDIEDGKFYCKPHYC 819
Query: 665 -----LPQTDHKAEGSDRGPES----PELPTPSENSMPPGLSTPTASQEGAGPVPDPSQP 715
Q A G E+ + T N +++ T G+G V +P
Sbjct: 820 YRLSGYAQRKRPAVAPLSGKEAKGPLQDGATTDANGRANAVASSTERTPGSG-VNGLEEP 878
Query: 716 TRRQIRLSSPERQRLSS--LNLTPDPEMEPPPKPPRSCSALARHALESSFVGWGLPVQSP 773
+ + +PER L + L+L ++ P+ + A H L SS + G
Sbjct: 879 SIAKRLRGTPERIELENYRLSLRQAEALQEVPEETQ-----AEHNL-SSVLDTG-----A 927
Query: 774 QALVAMEKEEKESPFSSEEEEED 796
+ VA E E EEEEE+
Sbjct: 928 EEDVASSSSESEMEEEGEEEEEE 950
Score = 125 bits (314), Expect = 2e-28
Identities = 104/346 (30%), Positives = 166/346 (47%), Gaps = 49/346 (14%)
Query: 672 AEGSDRGPESPELPTPSENSMPPGLSTPTASQEGAGPVPDPSQP-------------TRR 718
++G +R P+SP PT S P L S+E P D P +++
Sbjct: 1640 SQGKERRPDSPTRPT-LRGSEEPTLKHEATSEEVLSPPSDSGGPDGSFTSSEGSSGKSKK 1698
Query: 719 QIRLSSPERQRLSSLNLTPDPEMEPPPKPPRS----CSALARHALESSFVGW-------- 766
+ L SP R + + E PP KP + +A + +S F G+
Sbjct: 1699 RSSLFSPRRNKKEKKS---KGEGRPPEKPSSNLLEEAAAKPKSLWKSVFSGYKKDKKKKA 1755
Query: 767 -----------GLPVQSPQ--ALVAMEKEEKESPFSSEEEEEDVPLDSDVEQALQTFAK- 812
G V S + L + E + S E+ D+ D +E++ Q +
Sbjct: 1756 DDKSCPSTPSSGATVDSGKHRVLPVVRAELQLRRQLSFSEDSDLSSDDVLEKSSQKSRRE 1815
Query: 813 ----TSGTMNNYPTWR--RTLLRRAKEEEMKRFCKAQTIQRRLNEIEAALRELEAEGVKL 866
T +N T R + R+AK+EE+KR +AQ IQR+L ++E R LE GV +
Sbjct: 1816 PRTYTEEELNAKLTRRVQKAARRQAKQEELKRLHRAQIIQRQLQQVEERQRRLEERGVAV 1875
Query: 867 ELALRRQSSSPEQQKKLWVGQLLQLVDKKNSLVAEEAELMITVQELNLEEKQWQLDQELR 926
E ALR ++ ++ + + +LV +KN++V E+ELMI +EL LE++Q +L QELR
Sbjct: 1876 EKALRGEAGMGKKDDPKLMQEWFKLVQEKNAMVRYESELMIFARELELEDRQSRLQQELR 1935
Query: 927 GYMNREENLKTAADRQAEDQVLRKLVDLVNQRDALIRFQEERRLSE 972
M E++LKT + E Q+L +++++V QRD+L+ EE+RL E
Sbjct: 1936 ERMAVEDHLKTEEELSEEKQILNEMLEVVEQRDSLVALLEEQRLRE 1981
Score = 39.7 bits (91), Expect = 0.014
Identities = 41/183 (22%), Positives = 63/183 (34%), Gaps = 32/183 (17%)
Query: 671 KAEGSDRGPESPELPTPSENSMPPGLSTPTASQEGAGPVPDPSQPTRRQIRLSSPERQRL 730
K+ ++ P+ L S+P L P E +P P P+ R++R + ER+ L
Sbjct: 1364 KSYSVEKSPQDEGLHLLKPLSIPKRLGLPKPEGEPLS-LPTPRSPSDRELRSAQEERREL 1422
Query: 731 SSLN--------------------------LTPDPEMEPPPKPPRSCSALARHALESSFV 764
SS + LTP PPP P + L R E+
Sbjct: 1423 SSSSGLGLHGSSSNMKTLGSQSFNTSDSAMLTPPSSPPPPPPPGEEPATLRRKLREAEPN 1482
Query: 765 GWGLPVQSPQALVAMEKEEKESP-----FSSEEEEEDVPLDSDVEQALQTFAKTSGTMNN 819
+P P + +E + P S E E++P DVE + S
Sbjct: 1483 ASVVPPPLPATWMRPPREPAQPPREEVRKSFVESVEEIPFADDVEDTYDDKTEDSSLQEK 1542
Query: 820 YPT 822
+ T
Sbjct: 1543 FFT 1545
>gi|7662284 microtubule associated monoxygenase, calponin and LIM
domain containing 2 [Homo sapiens]
Length = 1124
Score = 353 bits (906), Expect = 4e-97
Identities = 179/300 (59%), Positives = 219/300 (73%), Gaps = 5/300 (1%)
Query: 14 FESFLQAQLCQDVLSSFQELCGALGLEPGGGLPQYHKIKDQLNYWSAKSLWTKLDKRAGQ 73
FE+F+QA C+ L +F L L L+P Y K+K ++ W AK+LW KLDKR
Sbjct: 16 FENFVQASTCKGTLQAFNILTRHLDLDPLDHRNFYSKLKSKVTTWKAKALWYKLDKRGSH 75
Query: 74 PVYQQGRACTSTKCLVVGAGPCGLRVAVELALLGARVVLVEKRTKFSRHNVLHLWPFTIH 133
Y++G++CT+TKCL+VG GPCGLR A+ELA LGA+VV+VEKR FSR+NVLHLWPFTIH
Sbjct: 76 KEYKRGKSCTNTKCLIVGGGPCGLRTAIELAYLGAKVVVVEKRDSFSRNNVLHLWPFTIH 135
Query: 134 DLRALGAKKFYGRFCTGTLDHISIRQLQLLLLKVALLLGVEIHWGVTFTGLQPPP----R 189
DLR LGAKKFYG+FC G++DHISIRQLQL+L KVAL+LGVEIH V F + PP
Sbjct: 136 DLRGLGAKKFYGKFCAGSIDHISIRQLQLILFKVALMLGVEIHVNVEFVKVLEPPEDQEN 195
Query: 190 KGSGWRAQLQPNPPAQLANYEFDVLISAAGGKFVPEGFKVREMRGKLAIGITANFVNGRT 249
+ GWRA+ P + L+ +EFDV+I A G + EGF+ +E RGKLAI ITANF+N +
Sbjct: 196 QKIGWRAEFLPTDHS-LSEFEFDVIIGADGRRNTLEGFRRKEFRGKLAIAITANFINRNS 254
Query: 250 VEETQVPEISGVARIYNQSFFQSLLKATGIDLENIVYYKDDTHYFVMTAKKQCLLRLGVL 309
E +V EISGVA I+NQ FFQ L + TGIDLENIVYYKD THYFVMTAKKQ LL GV+
Sbjct: 255 TAEAKVEEISGVAFIFNQKFFQDLKEETGIDLENIVYYKDCTHYFVMTAKKQSLLDKGVI 314
Score = 209 bits (531), Expect = 1e-53
Identities = 108/229 (47%), Positives = 145/229 (63%), Gaps = 5/229 (2%)
Query: 309 LRQPFWPLGTGVARGFLAAFDAAWMVKRWAEGAESLEVLAERESLYQLLSQTSPENMHRN 368
L +PFWP+GTG ARGFLAAFD AWMVK W +G LE+LAERESLY+LL QT+PEN+++N
Sbjct: 400 LLEPFWPMGTGCARGFLAAFDTAWMVKSWNQGTPPLELLAERESLYRLLPQTTPENINKN 459
Query: 369 VAQYGLDPATRYPNLNLRAVTPNQVRDLY--DVLAKEPVQR-NNDKTDTGMPATGSAGTQ 425
QY LDP TRYPNLN V P+QV+ LY L P++R + + + S
Sbjct: 460 FEQYTLDPGTRYPNLNSHCVRPHQVKHLYITKELEHYPLERLGSVRRSVNLSRKESDIRP 519
Query: 426 EELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATAW 485
+LL WCQ+QT GY V+V+DL++SW GLALCA+++R +P L+ L A+E
Sbjct: 520 SKLLTWCQQQTEGYQHVNVTDLTTSWRSGLALCAIIHRFRPELINFDSLNEDDAVENNQL 579
Query: 486 ALKVAENELGITPVVSAQAVVAGSDP--LGLIAYLSHFHSAFKSMAHSP 532
A VAE E GI PV + + + + +P L ++ YLS F+ F+ P
Sbjct: 580 AFDVAEREFGIPPVTTGKEMASAQEPDKLSMVMYLSKFYELFRGTPLRP 628
Score = 70.9 bits (172), Expect = 6e-12
Identities = 48/187 (25%), Positives = 67/187 (35%), Gaps = 41/187 (21%)
Query: 520 HFHSAFKSMAHSPGPVSQASPGTSSAVLFLSKLQRTLQRSRAKENAEDAGGKKLRLEMEA 579
HFH + H V + S G +A L L R +A+ + D + +
Sbjct: 937 HFHPSHLRTVHPQLTVGKVSSGIGAAAEVLVNLYMNDHRPKAQATSPDLESMRKSFPLNL 996
Query: 580 ETPSTEVPPDPEPGVPLTPPSQHQEAGAGDLCALCGEHLYVLERLCVNGHFFHRSCFRCH 639
G D C C + +YV+ERL GHFFHR CFRC
Sbjct: 997 --------------------------GGSDTCYFCKKRVYVMERLSAEGHFFHRECFRCS 1030
Query: 640 TCEATLWPGGYEQHPGDGHFYCLQHL---------------PQTDHKAEGSDRGPESPEL 684
C TL Y +G FYC H + + E + + E+P
Sbjct: 1031 ICATTLRLAAYTFDCDEGKFYCKPHFIHCKTNSKQRKRRAELKQQREEEATWQEQEAPRR 1090
Query: 685 PTPSENS 691
TP+E+S
Sbjct: 1091 DTPTESS 1097
>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
Length = 863
Score = 138 bits (348), Expect = 2e-32
Identities = 100/358 (27%), Positives = 150/358 (41%), Gaps = 49/358 (13%)
Query: 422 AGTQEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALE 481
AG + LL WC+ Q GY GV + DLSSS+ DGLA CA+++R +P LL+ L E
Sbjct: 2 AGPRGALLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFE 61
Query: 482 ATAWALKVAENELGITPVVSAQAVVAGSDP--LGLIAYLSHFHSAFKSMAHSPGPVSQAS 539
A +VAE ELGI ++ +V+ S P L ++ Y+S +++ F SPG +
Sbjct: 62 NNRLAFEVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHF----CSPGQAGVSP 117
Query: 540 PGTSSAVLFLSKLQRTLQRSRAKENAEDAGGKKLRLEMEAETPSTEVPPDPEPGVPLTPP 599
P A + T E+ L + +TPS+
Sbjct: 118 PRKGLAPCSPPSVAPTPVEPEDVAQGEELSSGSLSEQGTGQTPSS--------------- 162
Query: 600 SQHQEAGAGDLCALCGEHLYVLERLCVNGHFFHRSCFRCHTCEATLWPGGYEQHPGDGHF 659
CA C +H+++++R +G +HR CFRC C +TL PG YE P +G F
Sbjct: 163 ----------TCAACQQHVHLVQRYLADGRLYHRHCFRCRRCSSTLLPGAYENGPEEGTF 212
Query: 660 YCLQHLPQTDHKAEGSDR-GP--------------ESPELPTPSENSMPPG---LSTPTA 701
C +H + R GP ++ ++P +S P P A
Sbjct: 213 VCAEHCARLGPGTRSGTRPGPFSQPKQQHQQQLAEDAKDVPGGGPSSSAPAGAEADGPKA 272
Query: 702 SQEGAGPVPDPSQPTRRQIRLSSPERQRLSSLNLTPDPEMEPPPKPPRSCSALARHAL 759
S E +P + + L+SP R + P P PR S+L + L
Sbjct: 273 SPEARPQIPTKPRVPGKLQELASPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQENL 330
Score = 77.4 bits (189), Expect = 6e-14
Identities = 74/300 (24%), Positives = 129/300 (43%), Gaps = 19/300 (6%)
Query: 678 GPESPELPTPSENSMPPGLSTPTASQEGAGPVPDPSQPTRRQIRLSSPERQRLSSLNLTP 737
G E E P ++S P + P + S + ++ E+ +S L P
Sbjct: 524 GAELLEPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAP 583
Query: 738 DPEMEPPPKPPRSCSALARHALESSFVGWGLPVQSPQAL---VAMEKEEKESPFSSEEEE 794
P+P + CS L VG PV SP + + ++ KE+PF+ +
Sbjct: 584 RTRGSSGPQPAKPCSGATPTPL--LLVGDRSPVPSPGSSSPQLQVKSSCKENPFNRKPSP 641
Query: 795 EDVPLDSDVEQALQTFAKTSGTMNNYPTWRRTLLRRAKEEEMKRFCKAQTIQRRLNEIEA 854
P + + + + +P +R + + ++ + I ++ IE
Sbjct: 642 AASPATKKATKGSKP-VRPPAPGHGFPLIKRKV-------QADQYIPEEDIHGEMDTIER 693
Query: 855 ALRELEAEGVKLELALRRQSSSPEQQKKL--WVGQLLQLVDKKNSLVAEEAELMITVQEL 912
L LE GV LE LR + + L W +L+ +K+ LV E+EL+ ++
Sbjct: 694 RLDALEHRGVLLEEKLRGGLNEGREDDMLVDW----FKLIHEKHLLVRRESELIYVFKQQ 749
Query: 913 NLEEKQWQLDQELRGYMNREENLKTAADRQAEDQVLRKLVDLVNQRDALIRFQEERRLSE 972
NLE++Q ++ ELR +N+ E T DR E ++++LV L+ QR+A+I +E R E
Sbjct: 750 NLEQRQADVEYELRCLLNKPEKDWTEEDRAREKVLMQELVTLIEQRNAIINCLDEDRQRE 809
>gi|33667117 MICAL-like 2 isoform 1 [Homo sapiens]
Length = 904
Score = 130 bits (327), Expect = 6e-30
Identities = 94/345 (27%), Positives = 153/345 (44%), Gaps = 55/345 (15%)
Query: 428 LLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATAWAL 487
L +WC++Q GY V++ ++++S+ DGLA CA+++R +P L+ S L+ E A
Sbjct: 7 LQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYENNKLAF 66
Query: 488 KVAENELGITPVVSAQAVVAGSDP--LGLIAYLSHFHSAFKSMAHSPGPVSQASPGTSSA 545
+VAE LGI ++ A+ +VA P L ++ Y+S +++ F H P+ G +
Sbjct: 67 RVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYF----HGRSPI-----GGMAG 117
Query: 546 VLFLSKLQRTLQRSRAKENAEDAGGKKLRLE---MEAETPSTEVPPDPEPGVPLT----- 597
V + ++++ E+ GKK ++ + + P+ + P P P+
Sbjct: 118 V-----------KRASEDSEEEPSGKKAPVQAAKLPSPAPARKPPLSPAQTNPVVQRRNE 166
Query: 598 ----PPSQHQEAGAGDL----CALCGEHLYVLERLCVNGHFFHRSCFRCHTCEATLWPGG 649
PP + +A AG L C +CG+H+++++R +G +HRSCFRC C TL G
Sbjct: 167 GAGGPPPKTDQALAGSLVSSTCGVCGKHVHLVQRHLADGRLYHRSCFRCKQCSCTLHSGA 226
Query: 650 YEQHPGDGHFYCLQHLPQT-------------DHKAEGSDRGPESPELPTPSENSMPPGL 696
Y+ G F C HLP A G D N P
Sbjct: 227 YKATGEPGTFVCTSHLPAAASASPKLTGLVPRQPGAMGVDSRTSCSPQKAQEANKARPSA 286
Query: 697 STPTASQEGA----GPVPDPSQPTRRQIRLSSPERQRLSSLNLTP 737
P A A P+P+ + + + SP R S L TP
Sbjct: 287 WEPAAGNSPARASVPAAPNPAATSATSVHVRSPARPSESRLAPTP 331
Score = 71.2 bits (173), Expect = 4e-12
Identities = 46/134 (34%), Positives = 73/134 (54%), Gaps = 2/134 (1%)
Query: 839 FCKAQTIQRRLNEIEAALRELEAEGVKLELALRRQSSSPEQQKKLWVGQLLQLVDKKNSL 898
+ + IQR+L +IE L LE GV+LE LR + + + L V L+ +K L
Sbjct: 734 YLSPEEIQRQLQDIERRLDALELRGVELEKRLRA-AEGDDAEDSLMV-DWFWLIHEKQLL 791
Query: 899 VAEEAELMITVQELNLEEKQWQLDQELRGYMNREENLKTAADRQAEDQVLRKLVDLVNQR 958
+ +E+ELM + LEE+Q ++ ELR M + E LK+ +R+ E ++L + V VN R
Sbjct: 792 LRQESELMYKSKAQRLEEQQLDIEGELRRLMAKPEALKSLQERRREQELLEQYVSTVNDR 851
Query: 959 DALIRFQEERRLSE 972
++ +E RL E
Sbjct: 852 SDIVDSLDEDRLRE 865
>gi|118918413 MICAL C-terminal like [Homo sapiens]
Length = 695
Score = 119 bits (298), Expect = 1e-26
Identities = 81/238 (34%), Positives = 126/238 (52%), Gaps = 20/238 (8%)
Query: 737 PDPEMEPPPKPPRSCSALARHALESSFVGWGLPVQSPQALVAMEKEEKESPFSSEEEEED 796
P P PPP PP + A +++ P+++ Q A S S++EE
Sbjct: 459 PPPPPPPPPPPPTAGGADSKN----------FPLRA-QVTEASSSASSTSSSSADEE--- 504
Query: 797 VPLDSDVEQALQTFAKTSGTMNNYPTWRRTLLRRAKEEEMKRFCKAQTIQRRLNEIEAAL 856
D + +LQ K T+ + + + K+EE+KR KAQ IQR+L E+E
Sbjct: 505 ----FDPQLSLQL--KEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQ 558
Query: 857 RELEAEGVKLELALRRQSSSPEQQKKLWVGQLLQLVDKKNSLVAEEAELMITVQELNLEE 916
R E +GV+LE ALR ++ S Q + + + +LV +KN L+ E+EL+I QEL LE+
Sbjct: 559 RASEIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELED 618
Query: 917 KQWQLDQELRGYMNREENLKTAADRQAEDQVLRKLVDLVNQRDALIRFQEERRLSELA 974
Q +L+Q+LR M +EE+ K D E +V +L+ ++ QRD L+ EE+R+ E A
Sbjct: 619 HQSRLEQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKA 676
>gi|67782321 spectrin beta isoform a [Homo sapiens]
Length = 2328
Score = 76.6 bits (187), Expect = 1e-13
Identities = 40/105 (38%), Positives = 62/105 (59%), Gaps = 1/105 (0%)
Query: 425 QEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATA 484
++ LL WCQ +TAGYP V+V++ +SSW DGLA AL+++ +P L++ +L+ A
Sbjct: 176 KDALLLWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDKLKDSNARHNLE 235
Query: 485 WALKVAENELGITPVVSAQAV-VAGSDPLGLIAYLSHFHSAFKSM 528
A VAE +LGI P++ + V D +I Y+ F+ F M
Sbjct: 236 HAFNVAERQLGIIPLLDPEDVFTENPDEKSIITYVVAFYHYFSKM 280
>gi|67782319 spectrin beta isoform b [Homo sapiens]
Length = 2137
Score = 76.6 bits (187), Expect = 1e-13
Identities = 40/105 (38%), Positives = 62/105 (59%), Gaps = 1/105 (0%)
Query: 425 QEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATA 484
++ LL WCQ +TAGYP V+V++ +SSW DGLA AL+++ +P L++ +L+ A
Sbjct: 176 KDALLLWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDKLKDSNARHNLE 235
Query: 485 WALKVAENELGITPVVSAQAV-VAGSDPLGLIAYLSHFHSAFKSM 528
A VAE +LGI P++ + V D +I Y+ F+ F M
Sbjct: 236 HAFNVAERQLGIIPLLDPEDVFTENPDEKSIITYVVAFYHYFSKM 280
>gi|170016061 spectrin, beta, non-erythrocytic 5 [Homo sapiens]
Length = 3639
Score = 74.3 bits (181), Expect = 5e-13
Identities = 43/114 (37%), Positives = 64/114 (56%), Gaps = 2/114 (1%)
Query: 410 DKTDTGMPATGSAGTQEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLL 469
DK + G A T+E LL WCQ +TA Y V+++D S SW+DGL AL++ +P LL
Sbjct: 131 DKEEFGASAA-LLSTKEALLVWCQRKTASYTNVNITDFSRSWSDGLGFNALIHAHRPDLL 189
Query: 470 EPSELQGLGALEATAWALKVAENELGITPVVSAQAVVAGS-DPLGLIAYLSHFH 522
+ L+ L A+A VAE ELGI ++ + V A D ++ Y+S ++
Sbjct: 190 DYGSLRPDRPLHNLAFAFLVAEQELGIAQLLDPEDVAAAQPDERSIMTYVSLYY 243
>gi|150378549 tangerin [Homo sapiens]
Length = 1523
Score = 73.6 bits (179), Expect = 9e-13
Identities = 73/303 (24%), Positives = 126/303 (41%), Gaps = 54/303 (17%)
Query: 676 DRGPESPELPTPSE--------NSMPPG-----LSTPTASQEGAGPVPDPSQPTRRQIRL 722
D G E+P P+E + PG L P+ + E P + + +R
Sbjct: 1220 DGGAEAPRESRPAEVPAEGLVNGAGAPGGGGVRLRRPSVNGEPGSVPPPRAHGSFSHVRD 1279
Query: 723 SSPERQRLSSLNLTPDPEMEPPPKPPRSCSALARHALESSFVGWGLPVQSPQALVAMEKE 782
+ ++R S L + M+ P +A A + S P P +
Sbjct: 1280 ADLLKKRRSRLRNSSSFSMDDPDAGAMGAAAAEGQAPDPS------PAPGPPTAA----D 1329
Query: 783 EKESPFSSEEEEEDVPLDSDVEQALQTFAKTSGTMNNYPTWRRTLLRRAKEEEMKRFCKA 842
++ P S EE P + E LQ F TS
Sbjct: 1330 SQQPPGGSSPSEEPPPSPGE-EAGLQRFQDTS---------------------------- 1360
Query: 843 QTIQRRLNEIEAALRELEAEGVKLELALRR--QSSSPEQQKKLWVGQLLQLVDKKNSLVA 900
Q + L +E R+++ ++E+ LR +S + + Q+++ + + LV+KKN+L+
Sbjct: 1361 QYVCAELQALEQEQRQIDGRAAEVEMQLRSLMESGANKLQEEVLIQEWFTLVNKKNALIR 1420
Query: 901 EEAELMITVQELNLEEKQWQLDQELRGYMNREENLKTAADRQAEDQVLRKLVDLVNQRDA 960
+ +L + ++E +LE + L +ELR + E+ KT+A + E +L +LV LVNQRD
Sbjct: 1421 RQDQLQLLMEEQDLERRFELLSRELRAMLAIEDWQKTSAQQHREQLLLEELVSLVNQRDE 1480
Query: 961 LIR 963
L+R
Sbjct: 1481 LVR 1483
Score = 67.4 bits (163), Expect = 6e-11
Identities = 119/562 (21%), Positives = 206/562 (36%), Gaps = 87/562 (15%)
Query: 401 AKEPVQRNNDKTDTGMPATGS-AGTQEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCA 459
A P + D+ G A + + + LL WCQE T GY GV +++ ++SW +GLA CA
Sbjct: 1015 ASSPEKAEEDRRLPGSQAPPALVSSSQSLLEWCQEVTTGYRGVRITNFTTSWRNGLAFCA 1074
Query: 460 LVYRLQPGLLEPSELQGLGALEATAWALKVAENELGITPVVSAQAVVAGS--DPLGLIAY 517
+++R P ++ + L L + A LG++ ++ +V S D L ++ Y
Sbjct: 1075 ILHRFYPDKIDYASLDPLNIKQNNKQAFD-GFAALGVSRLLEPADMVLLSVPDKLIVMTY 1133
Query: 518 LSHFHS-------------------AFKSMAHSPGPVSQASPGTSSAVLFLSKLQRTLQR 558
L + ++ + P P G + L + +
Sbjct: 1134 LCQIRAFCTGQELQLVQLEGGGGAGTYRVGSAQPSPPDDLDAGGLAQRLRGHGAEGPQEP 1193
Query: 559 SRAKENAEDAG-GKKLRLEMEAETPSTEVPPDPEPGVPLTPPSQHQEAGAGDLCALCGEH 617
A + A+ A G R + P P P++ GAG G
Sbjct: 1194 KEAADRADGAAPGVASRNAVAGRASKDGGAEAPRESRPAEVPAEGLVNGAG----APGGG 1249
Query: 618 LYVLERLCVNGHFFHRSCFRCHTCEATLWPGGYEQHPGDGHFYCLQHLPQTDHKAEGSDR 677
L R VNG PG G F H+ D + R
Sbjct: 1250 GVRLRRPSVNGE-----------------PGSVPPPRAHGSF---SHVRDADLLKKRRSR 1289
Query: 678 GPESPELPTPSENSMPPGLSTPTASQEGA----GPVPDPSQPTRRQIRLSSPERQRLSSL 733
NS + P A GA G PDPS S + SS
Sbjct: 1290 ----------LRNSSSFSMDDPDAGAMGAAAAEGQAPDPSPAPGPPTAADSQQPPGGSS- 1338
Query: 734 NLTPDPEMEPPPKPPRSCSALARHALESSFVGWGLPVQSPQALVAMEKEEKESPFSSEEE 793
P EPPP P + L R S +V L A+E+E+++
Sbjct: 1339 -----PSEEPPPSPGEE-AGLQRFQDTSQYV--------CAELQALEQEQRQ--IDGRAA 1382
Query: 794 EEDVPLDSDVEQALQTFAKTSGTMNNYPTWRRTLLRRAKEEEMKRFCKAQTIQRRLNEIE 853
E ++ L S +E + + + ++++++ + Q ++RR E
Sbjct: 1383 EVEMQLRSLMESGANKLQEEVLIQEWFTLVNKKNALIRRQDQLQLLMEEQDLERR---FE 1439
Query: 854 AALRELEAEGVKLELALRRQSSSPEQQKKLWVGQLLQLVDKKNSLV--AEEAELMITVQE 911
REL A L + +++S+ + +++L + +L+ LV++++ LV + E + ++
Sbjct: 1440 LLSRELRA---MLAIEDWQKTSAQQHREQLLLEELVSLVNQRDELVRDLDHKERIALEED 1496
Query: 912 LNLEEKQWQLDQELRGYMNREE 933
LE Q ++L ++R E
Sbjct: 1497 ERLERGLEQRRRKLSRQLSRRE 1518
Score = 30.4 bits (67), Expect = 8.5
Identities = 17/58 (29%), Positives = 37/58 (63%), Gaps = 1/58 (1%)
Query: 914 LEEKQWQLD-QELRGYMNREENLKTAADRQAEDQVLRKLVDLVNQRDALIRFQEERRL 970
LE++Q Q+D + M +++ A++ E+ ++++ LVN+++ALIR Q++ +L
Sbjct: 1370 LEQEQRQIDGRAAEVEMQLRSLMESGANKLQEEVLIQEWFTLVNKKNALIRRQDQLQL 1427
>gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens]
Length = 2390
Score = 72.4 bits (176), Expect = 2e-12
Identities = 39/105 (37%), Positives = 62/105 (59%), Gaps = 1/105 (0%)
Query: 425 QEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATA 484
++ LL WCQ +TAGYP V+V + ++SW DGLA A+V++ +P LL+ L+ A
Sbjct: 179 KDALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQ 238
Query: 485 WALKVAENELGITPVVSAQAV-VAGSDPLGLIAYLSHFHSAFKSM 528
A +AE ELG+T ++ + V V D +I Y++ ++ F M
Sbjct: 239 NAFNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKM 283
>gi|4557241 actinin, alpha 3 [Homo sapiens]
Length = 901
Score = 71.2 bits (173), Expect = 4e-12
Identities = 39/103 (37%), Positives = 62/103 (60%), Gaps = 2/103 (1%)
Query: 425 QEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATA 484
+E LL WCQ +TA Y V+V + +SW DGLALCAL++R +P L++ ++L+ +
Sbjct: 161 KEGLLLWCQRKTAPYRNVNVQNFHTSWKDGLALCALIHRHRPDLIDYAKLRKDDPIGNLN 220
Query: 485 WALKVAENELGITPVVSAQAVV--AGSDPLGLIAYLSHFHSAF 525
A +VAE L I ++ A+ +V D ++ Y+S F+ AF
Sbjct: 221 TAFEVAEKYLDIPKMLDAEDIVNTPKPDEKAIMTYVSCFYHAF 263
>gi|4501893 actinin, alpha 2 [Homo sapiens]
Length = 894
Score = 71.2 bits (173), Expect = 4e-12
Identities = 37/103 (35%), Positives = 61/103 (59%), Gaps = 2/103 (1%)
Query: 425 QEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATA 484
+E LL WCQ +TA Y V++ + +SW DGL LCAL++R +P L++ S+L +
Sbjct: 154 KEGLLLWCQRKTAPYRNVNIQNFHTSWKDGLGLCALIHRHRPDLIDYSKLNKDDPIGNIN 213
Query: 485 WALKVAENELGITPVVSAQAVV--AGSDPLGLIAYLSHFHSAF 525
A+++AE L I ++ A+ +V D ++ Y+S F+ AF
Sbjct: 214 LAMEIAEKHLDIPKMLDAEDIVNTPKPDERAIMTYVSCFYHAF 256
Score = 30.8 bits (68), Expect = 6.5
Identities = 40/212 (18%), Positives = 92/212 (43%), Gaps = 16/212 (7%)
Query: 770 VQSPQALVAMEKEEKES-PFSSEEEEEDVPLDSDVEQALQTFAKTSGTMNNYPTWRRTLL 828
++ Q+L+ ++ K + P + E + + + ++VE+ +Q++ + N Y T L
Sbjct: 548 IEEIQSLITAHEQFKATLPEADGERQSIMAIQNEVEKVIQSYNIRISSSNPYSTVTMDEL 607
Query: 829 RRAKEEEMKRF--CKAQTIQRRLNEIEAALRELEAEGVKLELALRRQSSSPEQQKKL--- 883
R K +++K+ + Q++Q L R+ E ++ + A + + P Q K+
Sbjct: 608 -RTKWDKVKQLVPIRDQSLQEEL------ARQHANERLRRQFAAQANAIGPWIQNKMEEI 660
Query: 884 ---WVGQLLQLVDKKNSLVAEEAELMITVQELNLEEKQWQLDQELRGYMNREENLKTAAD 940
+ L D+ N L E ++ ++ E QL QE + N+ N
Sbjct: 661 ARSSIQITGALEDQMNQLKQYEHNIINYKNNIDKLEGDHQLIQEALVFDNKHTNYTMEHI 720
Query: 941 RQAEDQVLRKLVDLVNQRDALIRFQEERRLSE 972
R + +L + +N+ + I ++ + +++
Sbjct: 721 RVGWELLLTTIARTINEVETQILTRDAKGITQ 752
>gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1
[Homo sapiens]
Length = 2564
Score = 69.7 bits (169), Expect = 1e-11
Identities = 37/105 (35%), Positives = 60/105 (57%), Gaps = 1/105 (0%)
Query: 425 QEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATA 484
++ LL WCQ +TAGYP V++ + ++SW DGLA AL++R +P L++ S+L A
Sbjct: 183 KDALLLWCQMKTAGYPEVNIQNFTTSWRDGLAFNALIHRHRPDLVDFSKLTKSNANYNLQ 242
Query: 485 WALKVAENELGITPVVSAQAV-VAGSDPLGLIAYLSHFHSAFKSM 528
A + AE LG+ ++ + V + D +I Y+ F+ F M
Sbjct: 243 RAFRTAEQHLGLARLLDPEDVNMEAPDEKSIITYVVSFYHYFSKM 287
Score = 32.3 bits (72), Expect = 2.2
Identities = 27/116 (23%), Positives = 56/116 (48%), Gaps = 9/116 (7%)
Query: 843 QTIQRRLNEIEAALRELEAEGVKLELALRRQSS-----SPEQQKKLWVGQLLQLVDKKNS 897
Q +Q+ + + + RE++A G +LE L R + SPE + V + L+ + +
Sbjct: 1548 QAVQQHIKKNQGLRREIQAHGPRLEEVLERAGALASLRSPEAEA---VRRGLEQLQSAWA 1604
Query: 898 LVAEEAELMITVQELNLEEKQWQLD-QELRGYMNREENLKTAADRQAEDQVLRKLV 952
+ E AE V + + +Q+ D E+ ++ +E L + D+ ++Q +L+
Sbjct: 1605 GLREAAERRQQVLDAAFQVEQYYFDVAEVEAWLGEQELLMMSEDKGKDEQSTLQLL 1660
>gi|194097352 actinin, alpha 1 isoform c [Homo sapiens]
Length = 887
Score = 69.3 bits (168), Expect = 2e-11
Identities = 38/103 (36%), Positives = 58/103 (56%), Gaps = 2/103 (1%)
Query: 425 QEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATA 484
+E LL WCQ +TA Y V++ + SW DGL CAL++R +P L++ +L+ L
Sbjct: 147 KEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTNLN 206
Query: 485 WALKVAENELGITPVVSAQAVV--AGSDPLGLIAYLSHFHSAF 525
A VAE L I ++ A+ +V A D ++ Y+S F+ AF
Sbjct: 207 TAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAF 249
>gi|194097350 actinin, alpha 1 isoform a [Homo sapiens]
Length = 914
Score = 69.3 bits (168), Expect = 2e-11
Identities = 38/103 (36%), Positives = 58/103 (56%), Gaps = 2/103 (1%)
Query: 425 QEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATA 484
+E LL WCQ +TA Y V++ + SW DGL CAL++R +P L++ +L+ L
Sbjct: 147 KEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTNLN 206
Query: 485 WALKVAENELGITPVVSAQAVV--AGSDPLGLIAYLSHFHSAF 525
A VAE L I ++ A+ +V A D ++ Y+S F+ AF
Sbjct: 207 TAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAF 249
>gi|4501891 actinin, alpha 1 isoform b [Homo sapiens]
Length = 892
Score = 69.3 bits (168), Expect = 2e-11
Identities = 38/103 (36%), Positives = 58/103 (56%), Gaps = 2/103 (1%)
Query: 425 QEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATA 484
+E LL WCQ +TA Y V++ + SW DGL CAL++R +P L++ +L+ L
Sbjct: 147 KEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTNLN 206
Query: 485 WALKVAENELGITPVVSAQAVV--AGSDPLGLIAYLSHFHSAF 525
A VAE L I ++ A+ +V A D ++ Y+S F+ AF
Sbjct: 207 TAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAF 249
>gi|33188445 microfilament and actin filament cross-linker protein
isoform a [Homo sapiens]
Length = 5430
Score = 68.2 bits (165), Expect = 4e-11
Identities = 39/108 (36%), Positives = 61/108 (56%), Gaps = 2/108 (1%)
Query: 419 TGSAGTQEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLG 478
+G +E+LL W Q+ TAGY G+ ++ SS W+DG AL++R +P L++ +Q
Sbjct: 191 SGDMSAKEKLLLWTQKVTAGYTGIKCTNFSSCWSDGKMFNALIHRYRPDLVDMERVQIQS 250
Query: 479 ALEATAWALKVAENELGITPVVSAQAV-VAGSDPLGLIAYLSHFHSAF 525
E A +VAE LG+T ++ A+ V V D +I Y+S + AF
Sbjct: 251 NRENLEQAFEVAE-RLGVTRLLDAEDVDVPSPDEKSVITYVSSIYDAF 297
>gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo
sapiens]
Length = 2155
Score = 67.4 bits (163), Expect = 6e-11
Identities = 34/105 (32%), Positives = 61/105 (58%), Gaps = 1/105 (0%)
Query: 425 QEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATA 484
++ LL WCQ +TAGYP V++ + ++SW DG+A AL+++ +P L++ +L+ A
Sbjct: 163 KDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQ 222
Query: 485 WALKVAENELGITPVVSAQAV-VAGSDPLGLIAYLSHFHSAFKSM 528
A +AE LG+T ++ + + V D +I Y+ ++ F M
Sbjct: 223 NAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYVVTYYHYFSKM 267
>gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo
sapiens]
Length = 2364
Score = 67.4 bits (163), Expect = 6e-11
Identities = 34/105 (32%), Positives = 61/105 (58%), Gaps = 1/105 (0%)
Query: 425 QEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATA 484
++ LL WCQ +TAGYP V++ + ++SW DG+A AL+++ +P L++ +L+ A
Sbjct: 176 KDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQ 235
Query: 485 WALKVAENELGITPVVSAQAV-VAGSDPLGLIAYLSHFHSAFKSM 528
A +AE LG+T ++ + + V D +I Y+ ++ F M
Sbjct: 236 NAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYVVTYYHYFSKM 280
>gi|12025678 actinin, alpha 4 [Homo sapiens]
Length = 911
Score = 66.6 bits (161), Expect = 1e-10
Identities = 39/103 (37%), Positives = 59/103 (57%), Gaps = 2/103 (1%)
Query: 425 QEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATA 484
+E LL WCQ +TA Y V+V + SW DGLA AL++R +P L+E +L+ +
Sbjct: 166 KEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPELIEYDKLRKDDPVTNLN 225
Query: 485 WALKVAENELGITPVVSAQAVV--AGSDPLGLIAYLSHFHSAF 525
A +VAE L I ++ A+ +V A D ++ Y+S F+ AF
Sbjct: 226 NAFEVAEKYLDIPKMLDAEDIVNTARPDEKAIMTYVSSFYHAF 268
>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform
5 [Homo sapiens]
Length = 6907
Score = 66.2 bits (160), Expect = 1e-10
Identities = 48/179 (26%), Positives = 84/179 (46%), Gaps = 5/179 (2%)
Query: 395 DLYDVLAKEPVQRNNDKTDTGMPATGSAGTQEELLRWCQEQTAGYPGVHVSDLSSSWADG 454
D V+ P K + + A ++ LL W QEQ A Y V+V+D SSW +G
Sbjct: 154 DDVSVVDSSPASSPPAKKCSKVQARWQMSARKALLLWAQEQCATYESVNVTDFKSSWRNG 213
Query: 455 LALCALVYRLQPGLLEPSELQGLGALEATAWALKVAENELGITPVVSAQAV-VAGSDPLG 513
+A A+++ L+P L++ ++ + A ++AE EL I ++ + V V D
Sbjct: 214 MAFLAIIHALRPDLIDMKSVKHRSNKDNLREAFRIAEQELKIPRLLEPEDVDVVDPDEKS 273
Query: 514 LIAYLSHFHSAFKSMAHSPGPVSQASPGTSSAVLFLSKLQRTLQRSRAKENAEDAGGKK 572
++ Y++ F K +PG +A A+ +L+ LQ+ + K++ D KK
Sbjct: 274 IMTYVAQFLQYSKD---APGTGEEAQGKVKDAMGWLT-LQKEKLQKLLKDSENDTYFKK 328
Score = 30.8 bits (68), Expect = 6.5
Identities = 41/192 (21%), Positives = 80/192 (41%), Gaps = 21/192 (10%)
Query: 799 LDSDVEQALQTFA---KTSGTMNNYPTWRRTLLRRAKEEEMKRFCKAQTIQRRLNEIEAA 855
+ S V++ +TFA + M+N TW + + + C Q IQ+RL E +
Sbjct: 6010 IGSRVKKLKETFAFIQQLDKNMSNLRTWLARIESELSKPVVYDVCDDQEIQKRLAEQQDL 6069
Query: 856 LRELEAEGVKLE-------LALRRQSSSPEQQKKLWVGQLLQLVDKK-NSLVAEEAELMI 907
R++E +E + L + + + + Q + +D++ ++ A E +
Sbjct: 6070 QRDIEQHSAGVESVFNICDVLLHDSDACANETECDSIQQTTRSLDRRWRNICAMSMERRM 6129
Query: 908 TVQELNLEEKQWQLDQELRGYMNREENLKTAADRQA----EDQVLRKLVDLVNQRDALIR 963
++E W+L Q+ +R E+ +A+R A +VL +R +
Sbjct: 6130 KIEE------TWRLWQKFLDDYSRFEDWLKSAERTAACPNSSEVLYTSAKEELKRFEAFQ 6183
Query: 964 FQEERRLSELAL 975
Q RL++L L
Sbjct: 6184 RQIHERLTQLEL 6195
Score = 30.4 bits (67), Expect = 8.5
Identities = 31/145 (21%), Positives = 67/145 (46%), Gaps = 20/145 (13%)
Query: 834 EEMKRFCKAQTIQRRLNEIEA---ALRE--------LEAEGVKLELALRRQSSSPEQQKK 882
EE K F +I+R L+E++ LRE + A +KL AL P Q +
Sbjct: 341 EEKKSFLDVLSIKRDLDELDKDHLQLREAWDGLDHQINAWKIKLNYAL----PPPLHQTE 396
Query: 883 LWVGQLLQLVDKKNSLVAEEAELMITVQE-----LNLEEKQWQLDQELRGYMNREENLKT 937
W+ ++ +L+D+ S + ++ + +QE +L ++ L + N++EN
Sbjct: 397 AWLQEVEELMDEDLSASQDHSQAVTLIQEKMTLFKSLMDRFEHHSNILLTFENKDENHLP 456
Query: 938 AADRQAEDQVLRKLVDLVNQRDALI 962
+++ R++ +++ ++ L+
Sbjct: 457 LVPPNKLEEMKRRINNILEKKFILL 481
>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform
1 [Homo sapiens]
Length = 6885
Score = 66.2 bits (160), Expect = 1e-10
Identities = 48/179 (26%), Positives = 84/179 (46%), Gaps = 5/179 (2%)
Query: 395 DLYDVLAKEPVQRNNDKTDTGMPATGSAGTQEELLRWCQEQTAGYPGVHVSDLSSSWADG 454
D V+ P K + + A ++ LL W QEQ A Y V+V+D SSW +G
Sbjct: 154 DDVSVVDSSPASSPPAKKCSKVQARWQMSARKALLLWAQEQCATYESVNVTDFKSSWRNG 213
Query: 455 LALCALVYRLQPGLLEPSELQGLGALEATAWALKVAENELGITPVVSAQAV-VAGSDPLG 513
+A A+++ L+P L++ ++ + A ++AE EL I ++ + V V D
Sbjct: 214 MAFLAIIHALRPDLIDMKSVKHRSNKDNLREAFRIAEQELKIPRLLEPEDVDVVDPDEKS 273
Query: 514 LIAYLSHFHSAFKSMAHSPGPVSQASPGTSSAVLFLSKLQRTLQRSRAKENAEDAGGKK 572
++ Y++ F K +PG +A A+ +L+ LQ+ + K++ D KK
Sbjct: 274 IMTYVAQFLQYSKD---APGTGEEAQGKVKDAMGWLT-LQKEKLQKLLKDSENDTYFKK 328
Score = 30.8 bits (68), Expect = 6.5
Identities = 41/192 (21%), Positives = 80/192 (41%), Gaps = 21/192 (10%)
Query: 799 LDSDVEQALQTFA---KTSGTMNNYPTWRRTLLRRAKEEEMKRFCKAQTIQRRLNEIEAA 855
+ S V++ +TFA + M+N TW + + + C Q IQ+RL E +
Sbjct: 6010 IGSRVKKLKETFAFIQQLDKNMSNLRTWLARIESELSKPVVYDVCDDQEIQKRLAEQQDL 6069
Query: 856 LRELEAEGVKLE-------LALRRQSSSPEQQKKLWVGQLLQLVDKK-NSLVAEEAELMI 907
R++E +E + L + + + + Q + +D++ ++ A E +
Sbjct: 6070 QRDIEQHSAGVESVFNICDVLLHDSDACANETECDSIQQTTRSLDRRWRNICAMSMERRM 6129
Query: 908 TVQELNLEEKQWQLDQELRGYMNREENLKTAADRQA----EDQVLRKLVDLVNQRDALIR 963
++E W+L Q+ +R E+ +A+R A +VL +R +
Sbjct: 6130 KIEE------TWRLWQKFLDDYSRFEDWLKSAERTAACPNSSEVLYTSAKEELKRFEAFQ 6183
Query: 964 FQEERRLSELAL 975
Q RL++L L
Sbjct: 6184 RQIHERLTQLEL 6195
Score = 30.4 bits (67), Expect = 8.5
Identities = 31/145 (21%), Positives = 67/145 (46%), Gaps = 20/145 (13%)
Query: 834 EEMKRFCKAQTIQRRLNEIEA---ALRE--------LEAEGVKLELALRRQSSSPEQQKK 882
EE K F +I+R L+E++ LRE + A +KL AL P Q +
Sbjct: 341 EEKKSFLDVLSIKRDLDELDKDHLQLREAWDGLDHQINAWKIKLNYAL----PPPLHQTE 396
Query: 883 LWVGQLLQLVDKKNSLVAEEAELMITVQE-----LNLEEKQWQLDQELRGYMNREENLKT 937
W+ ++ +L+D+ S + ++ + +QE +L ++ L + N++EN
Sbjct: 397 AWLQEVEELMDEDLSASQDHSQAVTLIQEKMTLFKSLMDRFEHHSNILLTFENKDENHLP 456
Query: 938 AADRQAEDQVLRKLVDLVNQRDALI 962
+++ R++ +++ ++ L+
Sbjct: 457 LVPPNKLEEMKRRINNILEKKFILL 481
>gi|116517305 cysteine-rich protein 3 [Homo sapiens]
Length = 204
Score = 62.4 bits (150), Expect = 2e-09
Identities = 34/89 (38%), Positives = 45/89 (50%), Gaps = 7/89 (7%)
Query: 581 TPSTEVPPDPEPGVPL---TPPSQHQEAGAGDLCALCGEHLYVLERLCVNGHFFHRSCFR 637
+PS+ PP P G+P +PP G LC CGE +Y E++ G +HR C R
Sbjct: 91 SPSSFSPPRPRTGLPQGKKSPPHMKTFTGETSLCPGCGEPVYFAEKVMSLGRNWHRPCLR 150
Query: 638 CHTCEATLWPGGYEQHPGDGHFYCLQHLP 666
C C TL G + +H DG YC H+P
Sbjct: 151 CQRCHKTLTAGSHAEH--DGVPYC--HVP 175
Score = 47.0 bits (110), Expect = 9e-05
Identities = 33/115 (28%), Positives = 49/115 (42%), Gaps = 24/115 (20%)
Query: 611 CALCGEHLYVLERLCVNGHFFHRSCFRCHTCEATLWPGGYEQHPGDGHFYCLQHLPQTDH 670
C C + ++ E++ G +HR C +C C + L PGG+ +H +G YC H P
Sbjct: 5 CPRCQQPVFFAEKVSSLGKNWHRFCLKCERCHSILSPGGHAEH--NGRPYC--HKP---- 56
Query: 671 KAEGSDRGPESPEL----------PTPSENSMPPGLSTPTASQEGAGPVPDPSQP 715
G+ GP + PTPS PG +TP + + P P P
Sbjct: 57 -CYGALFGPRGVNIGGVGSYLYNPPTPS-----PGCTTPLSPSSFSPPRPRTGLP 105
>gi|224451082 cytospin A [Homo sapiens]
Length = 1117
Score = 60.1 bits (144), Expect = 1e-08
Identities = 45/179 (25%), Positives = 82/179 (45%), Gaps = 12/179 (6%)
Query: 357 LSQTSPENMHRNV-AQYGLDPATRYPNLNLRAVTPNQVRDLYDVLAKEPVQRNNDKTDTG 415
+S+ S E + R++ AQ G PA+ + + +P + P R+ + +
Sbjct: 943 VSRRSSEEVKRDISAQEGASPASL---MAMGTTSPQLSLSSSPTASVTPTTRSRIREERK 999
Query: 416 MPATGSA-----GTQEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLE 470
P + A + LL+WCQ++T GY + +++ SSSW DGLA CAL++ P +
Sbjct: 1000 DPLSALAREYGGSKRNALLKWCQKKTEGYQNIDITNFSSSWNDGLAFCALLHTYLPAHIP 1059
Query: 471 PSELQGLGALEATAWALKVAENELGITPVVSAQAVVAGSDP--LGLIAYLSHFHSAFKS 527
EL A + AE+ +GI + +V P ++ Y++ + F++
Sbjct: 1060 YQELNSQDKRRNFMLAFQAAES-VGIKSTLDINEMVRTERPDWQNVMLYVTAIYKYFET 1117
>gi|224451080 cytospin A [Homo sapiens]
Length = 1117
Score = 60.1 bits (144), Expect = 1e-08
Identities = 45/179 (25%), Positives = 82/179 (45%), Gaps = 12/179 (6%)
Query: 357 LSQTSPENMHRNV-AQYGLDPATRYPNLNLRAVTPNQVRDLYDVLAKEPVQRNNDKTDTG 415
+S+ S E + R++ AQ G PA+ + + +P + P R+ + +
Sbjct: 943 VSRRSSEEVKRDISAQEGASPASL---MAMGTTSPQLSLSSSPTASVTPTTRSRIREERK 999
Query: 416 MPATGSA-----GTQEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLE 470
P + A + LL+WCQ++T GY + +++ SSSW DGLA CAL++ P +
Sbjct: 1000 DPLSALAREYGGSKRNALLKWCQKKTEGYQNIDITNFSSSWNDGLAFCALLHTYLPAHIP 1059
Query: 471 PSELQGLGALEATAWALKVAENELGITPVVSAQAVVAGSDP--LGLIAYLSHFHSAFKS 527
EL A + AE+ +GI + +V P ++ Y++ + F++
Sbjct: 1060 YQELNSQDKRRNFMLAFQAAES-VGIKSTLDINEMVRTERPDWQNVMLYVTAIYKYFET 1117
>gi|169218211 PREDICTED: similar to plectin 1, partial [Homo
sapiens]
Length = 1369
Score = 60.1 bits (144), Expect = 1e-08
Identities = 33/101 (32%), Positives = 55/101 (54%), Gaps = 1/101 (0%)
Query: 425 QEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATA 484
+E+LL W Q GY G+ + +SSW DG A+++R +P L++ +++ LE
Sbjct: 294 KEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNAIIHRHKPLLIDMNKVYRQTNLENLD 353
Query: 485 WALKVAENELGITPVVSAQAV-VAGSDPLGLIAYLSHFHSA 524
A VAE +LG+T ++ + V V D +I Y+S + A
Sbjct: 354 QAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVSSLYDA 394
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,071,730
Number of Sequences: 37866
Number of extensions: 2355322
Number of successful extensions: 17198
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 121
Number of HSP's successfully gapped in prelim test: 652
Number of HSP's that attempted gapping in prelim test: 14195
Number of HSP's gapped (non-prelim): 3447
length of query: 981
length of database: 18,247,518
effective HSP length: 112
effective length of query: 869
effective length of database: 14,006,526
effective search space: 12171671094
effective search space used: 12171671094
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.