Guide to the Human Genome
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Name: ACTN2 Sequence: fasta or formatted (894aa) NCBI GI: 4501893
Description:

actinin, alpha 2

Referenced in:

LIM Domain Proteins
Spectrin and Plectin Families

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.4         75           2
 C cysteine            1.1         10           1
 D aspartate           6.0         54           2
 E glutamate          10.3         92           3
 F phenylalanine       3.1         28           1
 G glycine             3.9         35           1
 H histidine           2.6         23           1
 I isoleucine          7.4         66           2
 K lysine              5.9         53           2
 L leucine             9.4         84           3
 M methionine          3.2         29           1
 N asparagine          5.1         46           2
 P proline             3.1         28           2
 Q glutamine           6.2         55           2
 R arginine            6.7         60           2
 S serine              4.3         38           3
 T threonine           4.8         43           2
 V valine              3.7         33           1
 W tryptophan          1.8         16           1
 Y tyrosine            2.9         26           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   actinin, alpha 2 
ACTN3                 0.823   actinin, alpha 3 
ACTN1                 0.816   actinin, alpha 1 isoform c 
ACTN1                 0.808   actinin, alpha 1 isoform a 
ACTN1                 0.808   actinin, alpha 1 isoform b 
ACTN4                 0.789   actinin, alpha 4 
SPTBN1                0.230   spectrin, beta, non-erythrocytic 1 isoform 2 
SPTBN1                0.229   spectrin, beta, non-erythrocytic 1 isoform 1 
SPTBN2                0.229   spectrin, beta, non-erythrocytic 2 
SPTB                  0.221   spectrin beta isoform a 
SPTB                  0.221   spectrin beta isoform b 
SPTBN4                0.211   spectrin, beta, non-erythrocytic 4 isoform sigma1 [...
SPTBN5                0.181   spectrin, beta, non-erythrocytic 5 
SPTAN1                0.144   spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) ...
SPTAN1                0.144   spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) ...
PLEC1                 0.122   plectin 1 isoform 2 
PLEC1                 0.121   plectin 1 isoform 8 
PLEC1                 0.121   plectin 1 isoform 11 
PLEC1                 0.121   plectin 1 isoform 10 
PLEC1                 0.121   plectin 1 isoform 7 
PLEC1                 0.121   plectin 1 isoform 6 
PLEC1                 0.121   plectin 1 isoform 3 
PLEC1                 0.121   plectin 1 isoform 1 
DST                   0.120   dystonin isoform 1 
LOC652460             0.120   PREDICTED: similar to plectin 1, partial 
DST                   0.118   dystonin isoform 4 
DST                   0.118   dystonin isoform 3 
DST                   0.118   dystonin isoform 2 
MACF1                 0.115   microfilament and actin filament cross-linker protei...
SPTA1                 0.102   spectrin, alpha, erythrocytic 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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