Guide to the Human Genome
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Name: ACTN4 Sequence: fasta or formatted (911aa) NCBI GI: 12025678
Description:

actinin, alpha 4

Referenced in:

Spectrin and Plectin Families
Tripartite Motif Family

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.5         77           2
 C cysteine            0.9          8           1
 D aspartate           6.9         63           2
 E glutamate           9.5         87           2
 F phenylalanine       3.3         30           1
 G glycine             4.5         41           4
 H histidine           3.4         31           1
 I isoleucine          6.6         60           2
 K lysine              6.4         58           1
 L leucine             9.2         84           3
 M methionine          2.6         24           1
 N asparagine          5.0         46           2
 P proline             3.2         29           2
 Q glutamine           6.1         56           2
 R arginine            5.6         51           2
 S serine              5.2         47           2
 T threonine           4.5         41           2
 V valine              4.1         37           2
 W tryptophan          1.8         16           1
 Y tyrosine            2.7         25           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   actinin, alpha 4 
ACTN1                 0.853   actinin, alpha 1 isoform b 
ACTN1                 0.845   actinin, alpha 1 isoform a 
ACTN1                 0.835   actinin, alpha 1 isoform c 
ACTN2                 0.771   actinin, alpha 2 
ACTN3                 0.753   actinin, alpha 3 
SPTBN1                0.234   spectrin, beta, non-erythrocytic 1 isoform 1 
SPTBN1                0.234   spectrin, beta, non-erythrocytic 1 isoform 2 
SPTBN2                0.231   spectrin, beta, non-erythrocytic 2 
SPTB                  0.228   spectrin beta isoform a 
SPTB                  0.228   spectrin beta isoform b 
SPTBN4                0.212   spectrin, beta, non-erythrocytic 4 isoform sigma1 [...
SPTBN5                0.173   spectrin, beta, non-erythrocytic 5 
SPTAN1                0.146   spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) ...
SPTAN1                0.146   spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) ...
PLEC1                 0.126   plectin 1 isoform 1 
PLEC1                 0.125   plectin 1 isoform 8 
PLEC1                 0.124   plectin 1 isoform 11 
PLEC1                 0.124   plectin 1 isoform 10 
PLEC1                 0.124   plectin 1 isoform 7 
PLEC1                 0.124   plectin 1 isoform 6 
PLEC1                 0.124   plectin 1 isoform 3 
PLEC1                 0.124   plectin 1 isoform 2 
LOC652460             0.122   PREDICTED: similar to plectin 1, partial 
DST                   0.120   dystonin isoform 4 
DST                   0.120   dystonin isoform 3 
DST                   0.120   dystonin isoform 2 
DST                   0.120   dystonin isoform 1 
MACF1                 0.115   microfilament and actin filament cross-linker protei...
UTRN                  0.105   utrophin 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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