Guide to the Human Genome
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Name: MACF1 Sequence: fasta or formatted (5430aa) NCBI GI: 33188445
Description:

microfilament and actin filament cross-linker protein isoform a

Referenced in:

Additional Cell Cycle Functions
Cytoskeleton
Spectrin and Plectin Families

Other entries for this name:
alt prot [5938aa] microfilament and actin filament cross-linker protein isoform b
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.9        375           3
 C cysteine            1.2         63           2
 D aspartate           5.6        302           2
 E glutamate          11.0        595           4
 F phenylalanine       2.4        131           2
 G glycine             3.8        208           3
 H histidine           2.3        125           2
 I isoleucine          4.3        232           2
 K lysine              7.4        401           3
 L leucine            11.9        644           3
 M methionine          2.2        118           2
 N asparagine          3.3        179           2
 P proline             2.7        146           3
 Q glutamine           8.4        454           3
 R arginine            5.4        295           3
 S serine              7.9        430           4
 T threonine           5.2        282           3
 V valine              5.4        291           2
 W tryptophan          1.4         77           1
 Y tyrosine            1.5         82           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   microfilament and actin filament cross-linker protei... 
MACF1                 0.717   microfilament and actin filament cross-linker protei...
DST                   0.559   dystonin isoform 3 
DST                   0.559   dystonin isoform 2 
DST                   0.559   dystonin isoform 4 
DST                   0.553   dystonin isoform 1 
DST                   0.499   dystonin isoform 1eA precursor 
PLEC1                 0.132   plectin 1 isoform 1 
PLEC1                 0.128   plectin 1 isoform 11 
PLEC1                 0.128   plectin 1 isoform 7 
PLEC1                 0.128   plectin 1 isoform 3 
PLEC1                 0.128   plectin 1 isoform 10 
PLEC1                 0.128   plectin 1 isoform 8 
PLEC1                 0.128   plectin 1 isoform 6 
PLEC1                 0.128   plectin 1 isoform 2 
LOC652460             0.106   PREDICTED: similar to plectin 1, partial 
DST                   0.103   dystonin isoform 1eB precursor 
DST                   0.098   dystonin isoform 1e precursor 
DSP                   0.050   desmoplakin isoform I 
DSP                   0.046   desmoplakin isoform II 
SPTBN1                0.032   spectrin, beta, non-erythrocytic 1 isoform 1 
SPTBN1                0.032   spectrin, beta, non-erythrocytic 1 isoform 2 
SYNE1                 0.031   spectrin repeat containing, nuclear envelope 1 isofo...
SYNE1                 0.031   spectrin repeat containing, nuclear envelope 1 isof...
DMD                   0.031   dystrophin Dp427c isoform 
DMD                   0.031   dystrophin Dp427p2 isoform 
DMD                   0.031   dystrophin Dp427p1 isoform 
DMD                   0.031   dystrophin Dp427l isoform 
DMD                   0.031   dystrophin Dp427m isoform 
SPTBN5                0.030   spectrin, beta, non-erythrocytic 5 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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