Search of human proteins with 224831262

Search of human proteins with 224831262

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|224831262 calcium channel, voltage-dependent, beta 4 subunit
isoform d [Homo sapiens]
         (458 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|224831262 calcium channel, voltage-dependent, beta 4 subunit ...   904   0.0  
gi|54607064 calcium channel, voltage-dependent, beta 4 subunit i...   857   0.0  
gi|54607066 calcium channel, voltage-dependent, beta 4 subunit i...   814   0.0  
gi|54607068 calcium channel, voltage-dependent, beta 4 subunit i...   763   0.0  
gi|147901383 calcium channel, voltage-dependent, beta 2 subunit ...   560   e-159
gi|147904948 calcium channel, voltage-dependent, beta 2 subunit ...   539   e-153
gi|45359842 calcium channel, voltage-dependent, beta 2 subunit i...   539   e-153
gi|40804468 calcium channel, voltage-dependent, beta 1 subunit i...   538   e-153
gi|40804472 calcium channel, voltage-dependent, beta 1 subunit i...   538   e-153
gi|148223541 calcium channel, voltage-dependent, beta 2 subunit ...   534   e-152
gi|147898681 calcium channel, voltage-dependent, beta 2 subunit ...   534   e-152
gi|148226485 calcium channel, voltage-dependent, beta 2 subunit ...   520   e-148
gi|45359834 calcium channel, voltage-dependent, beta 2 subunit i...   520   e-147
gi|40316928 calcium channel, voltage-dependent, beta 3 subunit [...   517   e-147
gi|148232726 calcium channel, voltage-dependent, beta 2 subunit ...   516   e-146
gi|40804470 calcium channel, voltage-dependent, beta 1 subunit i...   507   e-143
gi|119943106 synapse-associated protein 102 isoform a [Homo sapi...    45   1e-04
gi|119943108 synapse-associated protein 102 isoform b [Homo sapi...    44   4e-04
gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]           42   0.001
gi|4557529 post-synaptic density protein 95 isoform 1 [Homo sapi...    40   0.003
gi|192447426 post-synaptic density protein 95 isoform 2 [Homo sa...    40   0.003
gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]           38   0.022
gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]                      38   0.022
gi|218156270 chapsyn-110 isoform 4 [Homo sapiens]                      38   0.022
gi|21361598 membrane protein, palmitoylated 6 [Homo sapiens]           37   0.029
gi|218156338 chapsyn-110 isoform 1 [Homo sapiens]                      37   0.037
gi|91199538 chapsyn-110 isoform 2 [Homo sapiens]                       37   0.037
gi|38570142 membrane protein, palmitoylated 5 [Homo sapiens]           36   0.064
gi|186700629 calcium/calmodulin-dependent serine protein kinase ...    36   0.083
gi|186700627 calcium/calmodulin-dependent serine protein kinase ...    36   0.083

>gi|224831262 calcium channel, voltage-dependent, beta 4 subunit
           isoform d [Homo sapiens]
          Length = 458

 Score =  904 bits (2336), Expect = 0.0
 Identities = 458/458 (100%), Positives = 458/458 (100%)

Query: 1   MSSSSYAKNGTADGPHSPTSQVARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPS 60
           MSSSSYAKNGTADGPHSPTSQVARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPS
Sbjct: 1   MSSSSYAKNGTADGPHSPTSQVARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPS 60

Query: 61  DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISF 120
           DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISF
Sbjct: 61  DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISF 120

Query: 121 DAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNS 180
           DAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNS
Sbjct: 121 DAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNS 180

Query: 181 SSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQK 240
           SSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQK
Sbjct: 181 SSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQK 240

Query: 241 ALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIF 300
           ALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIF
Sbjct: 241 ALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIF 300

Query: 301 ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQ 360
           ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQ
Sbjct: 301 ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQ 360

Query: 361 LVAADKLAQCPPSQRMRHSNHSTENSPIERRSLMTSDENYHNERARKSRNRLSSSSQHSR 420
           LVAADKLAQCPPSQRMRHSNHSTENSPIERRSLMTSDENYHNERARKSRNRLSSSSQHSR
Sbjct: 361 LVAADKLAQCPPSQRMRHSNHSTENSPIERRSLMTSDENYHNERARKSRNRLSSSSQHSR 420

Query: 421 DHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL 458
           DHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL
Sbjct: 421 DHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL 458


>gi|54607064 calcium channel, voltage-dependent, beta 4 subunit
           isoform b [Homo sapiens]
          Length = 520

 Score =  857 bits (2213), Expect = 0.0
 Identities = 451/520 (86%), Positives = 452/520 (86%), Gaps = 62/520 (11%)

Query: 1   MSSSSYAKNGTADGPHSPTSQVARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPS 60
           MSSSSYAKNGTADGPHSPTSQVARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPS
Sbjct: 1   MSSSSYAKNGTADGPHSPTSQVARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPS 60

Query: 61  DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISF 120
           DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISF
Sbjct: 61  DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISF 120

Query: 121 DAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNS 180
           DAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNS
Sbjct: 121 DAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNS 180

Query: 181 SSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQK 240
           SSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQK
Sbjct: 181 SSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQK 240

Query: 241 ALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIF 300
           ALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIF
Sbjct: 241 ALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIF 300

Query: 301 ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQ 360
           ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQ
Sbjct: 301 ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQ 360

Query: 361 LVAADKLAQCPPSQ-------------------------RMRHSNHST------------ 383
           LVAADKLAQCPP                           R  H+  ST            
Sbjct: 361 LVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGS 420

Query: 384 -------------------------ENSPIERRSLMTSDENYHNERARKSRNRLSSSSQH 418
                                    ENSPIERRSLMTSDENYHNERARKSRNRLSSSSQH
Sbjct: 421 TALSPYPTAISGLQSQRMRHSNHSTENSPIERRSLMTSDENYHNERARKSRNRLSSSSQH 480

Query: 419 SRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL 458
           SRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL
Sbjct: 481 SRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL 520


>gi|54607066 calcium channel, voltage-dependent, beta 4 subunit
           isoform c [Homo sapiens]
          Length = 502

 Score =  814 bits (2103), Expect = 0.0
 Identities = 430/499 (86%), Positives = 431/499 (86%), Gaps = 62/499 (12%)

Query: 22  VARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQA 81
           VARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQA
Sbjct: 4   VARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQA 63

Query: 82  AIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRL 141
           AIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRL
Sbjct: 64  AIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRL 123

Query: 142 VKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAK 201
           VKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAK
Sbjct: 124 VKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAK 183

Query: 202 QKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTA 261
           QKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTA
Sbjct: 184 QKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTA 243

Query: 262 DISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQ 321
           DISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQ
Sbjct: 244 DISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQ 303

Query: 322 LIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPSQ------- 374
           LIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPP         
Sbjct: 304 LIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDE 363

Query: 375 ------------------RMRHSNHST--------------------------------- 383
                             R  H+  ST                                 
Sbjct: 364 NQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTAISGLQSQRMRHS 423

Query: 384 ----ENSPIERRSLMTSDENYHNERARKSRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYK 439
               ENSPIERRSLMTSDENYHNERARKSRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYK
Sbjct: 424 NHSTENSPIERRSLMTSDENYHNERARKSRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYK 483

Query: 440 PHRNRGSPGGYSHDSRHRL 458
           PHRNRGSPGGYSHDSRHRL
Sbjct: 484 PHRNRGSPGGYSHDSRHRL 502


>gi|54607068 calcium channel, voltage-dependent, beta 4 subunit
           isoform a [Homo sapiens]
          Length = 486

 Score =  763 bits (1969), Expect = 0.0
 Identities = 402/471 (85%), Positives = 403/471 (85%), Gaps = 62/471 (13%)

Query: 50  GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 109
           GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE
Sbjct: 16  GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 75

Query: 110 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRG 169
           DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRG
Sbjct: 76  DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRG 135

Query: 170 RFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSL 229
           RFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSL
Sbjct: 136 RFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSL 195

Query: 230 KGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSL 289
           KGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSL
Sbjct: 196 KGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSL 255

Query: 290 AEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSR 349
           AEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSR
Sbjct: 256 AEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSR 315

Query: 350 GKSQSKHLNVQLVAADKLAQCPPSQ-------------------------RMRHSNHST- 383
           GKSQSKHLNVQLVAADKLAQCPP                           R  H+  ST 
Sbjct: 316 GKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTP 375

Query: 384 ------------------------------------ENSPIERRSLMTSDENYHNERARK 407
                                               ENSPIERRSLMTSDENYHNERARK
Sbjct: 376 MTPLLGRNLGSTALSPYPTAISGLQSQRMRHSNHSTENSPIERRSLMTSDENYHNERARK 435

Query: 408 SRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL 458
           SRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL
Sbjct: 436 SRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL 486


>gi|147901383 calcium channel, voltage-dependent, beta 2 subunit
           isoform 5 [Homo sapiens]
          Length = 622

 Score =  560 bits (1443), Expect = e-159
 Identities = 320/524 (61%), Positives = 367/524 (70%), Gaps = 96/524 (18%)

Query: 29  RRSRLKRSDGST----TSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQ 84
           R++R K SDGST    TS SF+ RQGSADSYTSRPSDSDVSLEEDREA+R+E E+QA  Q
Sbjct: 48  RKNRFKGSDGSTSSDTTSNSFV-RQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQ 106

Query: 85  LERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKE 144
           LE+AK+KPVAFAV+TNVSY  A ++DVPVP  AISF+AKDFLH+KEK+NNDWWIGRLVKE
Sbjct: 107 LEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKE 166

Query: 145 GCEIGFIPSPLRLENIRIQQEQ--KRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQ 202
           GCEIGFIPSP++LEN+R+Q EQ  K+G+F+  KS GNSSSSLG++V  + ++TP S+AKQ
Sbjct: 167 GCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAKQ 226

Query: 203 KQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTAD 262
           KQK TEH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRF+GRISITRVTAD
Sbjct: 227 KQKSTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTAD 286

Query: 263 ISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQL 322
           ISLAKRSVLNNPSK AIIERSNTRSSLAEVQSEIERIFELAR+LQLVVLDADTINHPAQL
Sbjct: 287 ISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQL 346

Query: 323 IKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPS--------- 373
            KTSLAPIIV+VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+VAADKLAQCPP          
Sbjct: 347 SKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDEN 406

Query: 374 ----------------QRMRHSNHSTENSPIERRSLMTS--------------------- 396
                            +  H   S+  +P+  R+L TS                     
Sbjct: 407 QLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRT 466

Query: 397 ------------DENYHNERARKSRNRLSSSSQH-----------------------SRD 421
                       +E    E  +KS++R SSS+ H                       SRD
Sbjct: 467 DRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRD 526

Query: 422 H-YPLVEEDYPDSYQDTYKPHRN-------RGSPGGYSHDSRHR 457
             Y   +EDY   + D Y  HR+        GS      +SRHR
Sbjct: 527 SAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 570


>gi|147904948 calcium channel, voltage-dependent, beta 2 subunit
           isoform 8 [Homo sapiens]
          Length = 608

 Score =  539 bits (1389), Expect = e-153
 Identities = 314/538 (58%), Positives = 362/538 (67%), Gaps = 110/538 (20%)

Query: 29  RRSRLKRSDGST----TSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQ 84
           R++R K SDGST    TS SF+ RQGSADSYTSRPSDSDVSLEEDREA+R+E E+QA  Q
Sbjct: 20  RKNRFKGSDGSTSSDTTSNSFV-RQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQ 78

Query: 85  LERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKE 144
           LE+AK+KPVAFAV+TNVSY  A ++DVPVP  AISF+AKDFLH+KEK+NNDWWIGRLVKE
Sbjct: 79  LEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKE 138

Query: 145 GCEIGFIPSPLRLENIRIQQEQ--KRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQ 202
           GCEIGFIPSP++LEN+R+Q EQ  K+G+F+  KS GNSSSSLG++V  + ++TP S+  +
Sbjct: 139 GCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSGAK 198

Query: 203 KQK--------------VTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH 248
                             TEH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH
Sbjct: 199 SADEQDQWKTAGLFWRFTTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH 258

Query: 249 RFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQL 308
           RF+GRISITRVTADISLAKRSVLNNPSK AIIERSNTRSSLAEVQSEIERIFELAR+LQL
Sbjct: 259 RFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQL 318

Query: 309 VVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLA 368
           VVLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+VAADKLA
Sbjct: 319 VVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLA 378

Query: 369 QCPPS-------------------------QRMRHSNHSTENSPIERRSLMTS------- 396
           QCPP                           +  H   S+  +P+  R+L TS       
Sbjct: 379 QCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPT 438

Query: 397 --------------------------DENYHNERARKSRNRLSSSSQH------------ 418
                                     +E    E  +KS++R SSS+ H            
Sbjct: 439 LASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLS 498

Query: 419 -----------SRDH-YPLVEEDYPDSYQDTYKPHRN-------RGSPGGYSHDSRHR 457
                      SRD  Y   +EDY   + D Y  HR+        GS      +SRHR
Sbjct: 499 RQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 556


>gi|45359842 calcium channel, voltage-dependent, beta 2 subunit
           isoform 4 [Homo sapiens]
          Length = 636

 Score =  539 bits (1389), Expect = e-153
 Identities = 314/538 (58%), Positives = 362/538 (67%), Gaps = 110/538 (20%)

Query: 29  RRSRLKRSDGST----TSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQ 84
           R++R K SDGST    TS SF+ RQGSADSYTSRPSDSDVSLEEDREA+R+E E+QA  Q
Sbjct: 48  RKNRFKGSDGSTSSDTTSNSFV-RQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQ 106

Query: 85  LERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKE 144
           LE+AK+KPVAFAV+TNVSY  A ++DVPVP  AISF+AKDFLH+KEK+NNDWWIGRLVKE
Sbjct: 107 LEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKE 166

Query: 145 GCEIGFIPSPLRLENIRIQQEQ--KRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQ 202
           GCEIGFIPSP++LEN+R+Q EQ  K+G+F+  KS GNSSSSLG++V  + ++TP S+  +
Sbjct: 167 GCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSGAK 226

Query: 203 KQK--------------VTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH 248
                             TEH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH
Sbjct: 227 SADEQDQWKTAGLFWRFTTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKH 286

Query: 249 RFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQL 308
           RF+GRISITRVTADISLAKRSVLNNPSK AIIERSNTRSSLAEVQSEIERIFELAR+LQL
Sbjct: 287 RFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQL 346

Query: 309 VVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLA 368
           VVLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+VAADKLA
Sbjct: 347 VVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLA 406

Query: 369 QCPPS-------------------------QRMRHSNHSTENSPIERRSLMTS------- 396
           QCPP                           +  H   S+  +P+  R+L TS       
Sbjct: 407 QCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPT 466

Query: 397 --------------------------DENYHNERARKSRNRLSSSSQH------------ 418
                                     +E    E  +KS++R SSS+ H            
Sbjct: 467 LASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLS 526

Query: 419 -----------SRDH-YPLVEEDYPDSYQDTYKPHRN-------RGSPGGYSHDSRHR 457
                      SRD  Y   +EDY   + D Y  HR+        GS      +SRHR
Sbjct: 527 RQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 584


>gi|40804468 calcium channel, voltage-dependent, beta 1 subunit
           isoform 1 [Homo sapiens]
          Length = 598

 Score =  538 bits (1385), Expect = e-153
 Identities = 277/380 (72%), Positives = 321/380 (84%), Gaps = 16/380 (4%)

Query: 8   KNGTADGPHSPTSQVARGT---------TTRRSRLKRSDGST----TSTSFILRQGSADS 54
           K   + GP+ P+ ++             + R+ R KRSDGST    TS SF+ RQGSA+S
Sbjct: 4   KTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFV-RQGSAES 62

Query: 55  YTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVP 114
           YTSRPSDSDVSLEEDREA+R+E E+QA  QLE+AK+KPVAFAV+TNV Y  +  ++VPV 
Sbjct: 63  YTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQ 122

Query: 115 STAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQK--RGRFH 172
             AI+F+ KDFLHIKEKYNNDWWIGRLVKEGCE+GFIPSP++L+++R+ QEQK  + R  
Sbjct: 123 GVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLG 182

Query: 173 GGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKGY 232
             KS  NSSSSLG++V+GT R TP ++AKQKQK TEH+PPYDVVPSMRP++LVGPSLKGY
Sbjct: 183 SSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVGPSLKGY 242

Query: 233 EVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEV 292
           EVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSK  IIERSNTRSSLAEV
Sbjct: 243 EVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEV 302

Query: 293 QSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKS 352
           QSEIERIFELAR+LQLV LDADTINHPAQL KTSLAPIIV++K++SPKVLQRLIKSRGKS
Sbjct: 303 QSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKS 362

Query: 353 QSKHLNVQLVAADKLAQCPP 372
           QSKHLNVQ+ A++KLAQCPP
Sbjct: 363 QSKHLNVQIAASEKLAQCPP 382


>gi|40804472 calcium channel, voltage-dependent, beta 1 subunit
           isoform 3 [Homo sapiens]
          Length = 478

 Score =  538 bits (1385), Expect = e-153
 Identities = 277/380 (72%), Positives = 321/380 (84%), Gaps = 16/380 (4%)

Query: 8   KNGTADGPHSPTSQVARGT---------TTRRSRLKRSDGST----TSTSFILRQGSADS 54
           K   + GP+ P+ ++             + R+ R KRSDGST    TS SF+ RQGSA+S
Sbjct: 4   KTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFV-RQGSAES 62

Query: 55  YTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVP 114
           YTSRPSDSDVSLEEDREA+R+E E+QA  QLE+AK+KPVAFAV+TNV Y  +  ++VPV 
Sbjct: 63  YTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQ 122

Query: 115 STAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQK--RGRFH 172
             AI+F+ KDFLHIKEKYNNDWWIGRLVKEGCE+GFIPSP++L+++R+ QEQK  + R  
Sbjct: 123 GVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLG 182

Query: 173 GGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKGY 232
             KS  NSSSSLG++V+GT R TP ++AKQKQK TEH+PPYDVVPSMRP++LVGPSLKGY
Sbjct: 183 SSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVGPSLKGY 242

Query: 233 EVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEV 292
           EVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSK  IIERSNTRSSLAEV
Sbjct: 243 EVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEV 302

Query: 293 QSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKS 352
           QSEIERIFELAR+LQLV LDADTINHPAQL KTSLAPIIV++K++SPKVLQRLIKSRGKS
Sbjct: 303 QSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKS 362

Query: 353 QSKHLNVQLVAADKLAQCPP 372
           QSKHLNVQ+ A++KLAQCPP
Sbjct: 363 QSKHLNVQIAASEKLAQCPP 382


>gi|148223541 calcium channel, voltage-dependent, beta 2 subunit
           isoform 6 [Homo sapiens]
          Length = 632

 Score =  534 bits (1376), Expect = e-152
 Identities = 318/562 (56%), Positives = 367/562 (65%), Gaps = 134/562 (23%)

Query: 29  RRSRLKRSDGST----TSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQ 84
           R++R K SDGST    TS SF+ RQGSADSYTSRPSDSDVSLEEDREA+R+E E+QA  Q
Sbjct: 20  RKNRFKGSDGSTSSDTTSNSFV-RQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQ 78

Query: 85  LERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKE 144
           LE+AK+KPVAFAV+TNVSY  A ++DVPVP  AISF+AKDFLH+KEK+NNDWWIGRLVKE
Sbjct: 79  LEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKE 138

Query: 145 GCEIGFIPSPLRLENIRIQQEQ--KRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTA-- 200
           GCEIGFIPSP++LEN+R+Q EQ  K+G+F+  KS GNSSSSLG++V  + ++TP S+A  
Sbjct: 139 GCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAID 198

Query: 201 --------------------------------KQKQ----KVTEHIPPYDVVPSMRPVVL 224
                                           K+K+    K TEH PPYDVVPSMRPVVL
Sbjct: 199 IDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVL 258

Query: 225 VGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSN 284
           VGPSLKGYEVTDMMQKALFDFLKHRF+GRISITRVTADISLAKRSVLNNPSK AIIERSN
Sbjct: 259 VGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSN 318

Query: 285 TRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQR 344
           TRSSLAEVQSEIERIFELAR+LQLVVLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQR
Sbjct: 319 TRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQR 378

Query: 345 LIKSRGKSQSKHLNVQLVAADKLAQCPPS-------------------------QRMRHS 379
           LIKSRGKSQ+KHLNVQ+VAADKLAQCPP                           +  H 
Sbjct: 379 LIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHP 438

Query: 380 NHSTENSPIERRSLMTS---------------------------------DENYHNERAR 406
             S+  +P+  R+L TS                                 +E    E  +
Sbjct: 439 PSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVK 498

Query: 407 KSRNRLSSSSQH-----------------------SRDH-YPLVEEDYPDSYQDTYKPHR 442
           KS++R SSS+ H                       SRD  Y   +EDY   + D Y  HR
Sbjct: 499 KSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHR 558

Query: 443 N-------RGSPGGYSHDSRHR 457
           +        GS      +SRHR
Sbjct: 559 DHNHRDETHGSSDHRHRESRHR 580


>gi|147898681 calcium channel, voltage-dependent, beta 2 subunit
           isoform 2 [Homo sapiens]
          Length = 660

 Score =  534 bits (1376), Expect = e-152
 Identities = 318/562 (56%), Positives = 367/562 (65%), Gaps = 134/562 (23%)

Query: 29  RRSRLKRSDGST----TSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQ 84
           R++R K SDGST    TS SF+ RQGSADSYTSRPSDSDVSLEEDREA+R+E E+QA  Q
Sbjct: 48  RKNRFKGSDGSTSSDTTSNSFV-RQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQ 106

Query: 85  LERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKE 144
           LE+AK+KPVAFAV+TNVSY  A ++DVPVP  AISF+AKDFLH+KEK+NNDWWIGRLVKE
Sbjct: 107 LEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKE 166

Query: 145 GCEIGFIPSPLRLENIRIQQEQ--KRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTA-- 200
           GCEIGFIPSP++LEN+R+Q EQ  K+G+F+  KS GNSSSSLG++V  + ++TP S+A  
Sbjct: 167 GCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAID 226

Query: 201 --------------------------------KQKQ----KVTEHIPPYDVVPSMRPVVL 224
                                           K+K+    K TEH PPYDVVPSMRPVVL
Sbjct: 227 IDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVL 286

Query: 225 VGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSN 284
           VGPSLKGYEVTDMMQKALFDFLKHRF+GRISITRVTADISLAKRSVLNNPSK AIIERSN
Sbjct: 287 VGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSN 346

Query: 285 TRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQR 344
           TRSSLAEVQSEIERIFELAR+LQLVVLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQR
Sbjct: 347 TRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQR 406

Query: 345 LIKSRGKSQSKHLNVQLVAADKLAQCPPS-------------------------QRMRHS 379
           LIKSRGKSQ+KHLNVQ+VAADKLAQCPP                           +  H 
Sbjct: 407 LIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHP 466

Query: 380 NHSTENSPIERRSLMTS---------------------------------DENYHNERAR 406
             S+  +P+  R+L TS                                 +E    E  +
Sbjct: 467 PSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVK 526

Query: 407 KSRNRLSSSSQH-----------------------SRDH-YPLVEEDYPDSYQDTYKPHR 442
           KS++R SSS+ H                       SRD  Y   +EDY   + D Y  HR
Sbjct: 527 KSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHR 586

Query: 443 N-------RGSPGGYSHDSRHR 457
           +        GS      +SRHR
Sbjct: 587 DHNHRDETHGSSDHRHRESRHR 608


>gi|148226485 calcium channel, voltage-dependent, beta 2 subunit
           isoform 3 [Homo sapiens]
          Length = 606

 Score =  520 bits (1340), Expect = e-148
 Identities = 306/544 (56%), Positives = 354/544 (65%), Gaps = 129/544 (23%)

Query: 43  TSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVS 102
           T +I+  GSADSYTSRPSDSDVSLEEDREA+R+E E+QA  QLE+AK+KPVAFAV+TNVS
Sbjct: 11  TKYIIPGGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVS 70

Query: 103 YCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRI 162
           Y  A ++DVPVP  AISF+AKDFLH+KEK+NNDWWIGRLVKEGCEIGFIPSP++LEN+R+
Sbjct: 71  YSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRL 130

Query: 163 QQEQ--KRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTA-------------------- 200
           Q EQ  K+G+F+  KS GNSSSSLG++V  + ++TP S+A                    
Sbjct: 131 QHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHR 190

Query: 201 --------------KQKQ----KVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKAL 242
                         K+K+    K TEH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKAL
Sbjct: 191 SPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKAL 250

Query: 243 FDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFEL 302
           FDFLKHRF+GRISITRVTADISLAKRSVLNNPSK AIIERSNTRSSLAEVQSEIERIFEL
Sbjct: 251 FDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFEL 310

Query: 303 ARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLV 362
           AR+LQLVVLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+V
Sbjct: 311 ARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMV 370

Query: 363 AADKLAQCPPS-------------------------QRMRHSNHSTENSPIERRSLMTS- 396
           AADKLAQCPP                           +  H   S+  +P+  R+L TS 
Sbjct: 371 AADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSS 430

Query: 397 --------------------------------DENYHNERARKSRNRLSSSSQH------ 418
                                           +E    E  +KS++R SSS+ H      
Sbjct: 431 LPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSG 490

Query: 419 -----------------SRDH-YPLVEEDYPDSYQDTYKPHRN-------RGSPGGYSHD 453
                            SRD  Y   +EDY   + D Y  HR+        GS      +
Sbjct: 491 TSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRE 550

Query: 454 SRHR 457
           SRHR
Sbjct: 551 SRHR 554


>gi|45359834 calcium channel, voltage-dependent, beta 2 subunit
           isoform 7 [Homo sapiens]
          Length = 612

 Score =  520 bits (1339), Expect = e-147
 Identities = 310/554 (55%), Positives = 357/554 (64%), Gaps = 131/554 (23%)

Query: 33  LKRSDGSTTSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKP 92
           LKR+ G     S I   GSADSYTSRPSDSDVSLEEDREA+R+E E+QA  QLE+AK+KP
Sbjct: 9   LKRAKGGRLKNSDIC--GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKP 66

Query: 93  VAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIP 152
           VAFAV+TNVSY  A ++DVPVP  AISF+AKDFLH+KEK+NNDWWIGRLVKEGCEIGFIP
Sbjct: 67  VAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIP 126

Query: 153 SPLRLENIRIQQEQ--KRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTA---------- 200
           SP++LEN+R+Q EQ  K+G+F+  KS GNSSSSLG++V  + ++TP S+A          
Sbjct: 127 SPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDA 186

Query: 201 ------------------------KQKQ----KVTEHIPPYDVVPSMRPVVLVGPSLKGY 232
                                   K+K+    K TEH PPYDVVPSMRPVVLVGPSLKGY
Sbjct: 187 EENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGY 246

Query: 233 EVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEV 292
           EVTDMMQKALFDFLKHRF+GRISITRVTADISLAKRSVLNNPSK AIIERSNTRSSLAEV
Sbjct: 247 EVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEV 306

Query: 293 QSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKS 352
           QSEIERIFELAR+LQLVVLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQRLIKSRGKS
Sbjct: 307 QSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKS 366

Query: 353 QSKHLNVQLVAADKLAQCPPS-------------------------QRMRHSNHSTENSP 387
           Q+KHLNVQ+VAADKLAQCPP                           +  H   S+  +P
Sbjct: 367 QAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNP 426

Query: 388 IERRSLMTS---------------------------------DENYHNERARKSRNRLSS 414
           +  R+L TS                                 +E    E  +KS++R SS
Sbjct: 427 LLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSS 486

Query: 415 SSQH-----------------------SRDH-YPLVEEDYPDSYQDTYKPHRN------- 443
           S+ H                       SRD  Y   +EDY   + D Y  HR+       
Sbjct: 487 SAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDET 546

Query: 444 RGSPGGYSHDSRHR 457
            GS      +SRHR
Sbjct: 547 HGSSDHRHRESRHR 560


>gi|40316928 calcium channel, voltage-dependent, beta 3 subunit
           [Homo sapiens]
          Length = 484

 Score =  517 bits (1332), Expect = e-147
 Identities = 294/461 (63%), Positives = 326/461 (70%), Gaps = 69/461 (14%)

Query: 50  GSADSYTSRPS-DSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALD 108
           GSADSYTSRPS DSDVSLEEDRE+ R+E E QA  QLERAK KPVAFAV+TNVSYCG LD
Sbjct: 16  GSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLD 75

Query: 109 EDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKR 168
           E+ PV  + ++F+AKDFLHIKEKY+NDWWIGRLVKEG +I FIPSP RLE+IR++QEQK 
Sbjct: 76  EECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPSPQRLESIRLKQEQKA 135

Query: 169 GRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPS 228
            R      SGN SS L ++  G  R+ P S AKQKQK  EH+PPYDVVPSMRPVVLVGPS
Sbjct: 136 RR------SGNPSS-LSDI--GNRRSPPPSLAKQKQKQAEHVPPYDVVPSMRPVVLVGPS 186

Query: 229 LKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSS 288
           LKGYEVTDMMQKALFDFLKHRFDGRISITRVTAD+SLAKRSVLNNP KR IIERS+ RSS
Sbjct: 187 LKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSARSS 246

Query: 289 LAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKS 348
           +AEVQSEIERIFELA+SLQLVVLDADTINHPAQL KTSLAPIIV VKVSSPKVLQRLI+S
Sbjct: 247 IAEVQSEIERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRS 306

Query: 349 RGKSQSKHLNVQLVAADKLAQCPPSQ-------------------------RMRH----- 378
           RGKSQ KHL VQ++A DKL QCPP                           R  H     
Sbjct: 307 RGKSQMKHLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLAEYLEVYWRATHHPAPG 366

Query: 379 -------------------SNHSTENSPIERRSLMTSDENYHNERARKSRNRLSSSSQHS 419
                                   E+SP+ER SLM SD     E +  SR   + SSQ S
Sbjct: 367 PGLLGPPSAIPGLQNQQLLGERGEEHSPLERDSLMPSD-----EASESSRQAWTGSSQRS 421

Query: 420 RDHYPLVEEDYPDSYQDTYKPHRNR--GSPGGYSHDSRHRL 458
             H   +EEDY D+YQD Y+PHR    G P    HD + RL
Sbjct: 422 SRH---LEEDYADAYQDLYQPHRQHTSGLPSANGHDPQDRL 459


>gi|148232726 calcium channel, voltage-dependent, beta 2 subunit
           isoform 1 [Homo sapiens]
          Length = 605

 Score =  516 bits (1330), Expect = e-146
 Identities = 304/537 (56%), Positives = 350/537 (65%), Gaps = 129/537 (24%)

Query: 50  GSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDE 109
           GSADSYTSRPSDSDVSLEEDREA+R+E E+QA  QLE+AK+KPVAFAV+TNVSY  A ++
Sbjct: 17  GSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHED 76

Query: 110 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQ--K 167
           DVPVP  AISF+AKDFLH+KEK+NNDWWIGRLVKEGCEIGFIPSP++LEN+R+Q EQ  K
Sbjct: 77  DVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAK 136

Query: 168 RGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTA--------------------------- 200
           +G+F+  KS GNSSSSLG++V  + ++TP S+A                           
Sbjct: 137 QGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSAN 196

Query: 201 -------KQKQ----KVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 249
                  K+K+    K TEH PPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR
Sbjct: 197 SVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHR 256

Query: 250 FDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLV 309
           F+GRISITRVTADISLAKRSVLNNPSK AIIERSNTRSSLAEVQSEIERIFELAR+LQLV
Sbjct: 257 FEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLV 316

Query: 310 VLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQ 369
           VLDADTINHPAQL KTSLAPIIV+VK+SSPKVLQRLIKSRGKSQ+KHLNVQ+VAADKLAQ
Sbjct: 317 VLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQ 376

Query: 370 CPPS-------------------------QRMRHSNHSTENSPIERRSLMTS-------- 396
           CPP                           +  H   S+  +P+  R+L TS        
Sbjct: 377 CPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTL 436

Query: 397 -------------------------DENYHNERARKSRNRLSSSSQH------------- 418
                                    +E    E  +KS++R SSS+ H             
Sbjct: 437 ASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSR 496

Query: 419 ----------SRDH-YPLVEEDYPDSYQDTYKPHRN-------RGSPGGYSHDSRHR 457
                     SRD  Y   +EDY   + D Y  HR+        GS      +SRHR
Sbjct: 497 QETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHR 553


>gi|40804470 calcium channel, voltage-dependent, beta 1 subunit
           isoform 2 [Homo sapiens]
          Length = 523

 Score =  507 bits (1305), Expect = e-143
 Identities = 272/425 (64%), Positives = 317/425 (74%), Gaps = 61/425 (14%)

Query: 8   KNGTADGPHSPTSQVARGT---------TTRRSRLKRSDGST----TSTSFILRQGSADS 54
           K   + GP+ P+ ++             + R+ R KRSDGST    TS SF+ RQGSA+S
Sbjct: 4   KTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFV-RQGSAES 62

Query: 55  YTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVP 114
           YTSRPSDSDVSLEEDREA+R+E E+QA  QLE+AK+KPVAFAV+TNV Y  +  ++VPV 
Sbjct: 63  YTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQ 122

Query: 115 STAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQK--RGRFH 172
             AI+F+ KDFLHIKEKYNNDWWIGRLVKEGCE+GFIPSP++L+++R+ QEQK  + R  
Sbjct: 123 GVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLG 182

Query: 173 GGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQ---------------------------- 204
             KS  NSSSSLG++V+GT R TP ++  +                              
Sbjct: 183 SSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNLAFELDPLELEEEEAELGEQSGSAKTS 242

Query: 205 -----------------KVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLK 247
                            K TEH+PPYDVVPSMRP++LVGPSLKGYEVTDMMQKALFDFLK
Sbjct: 243 VSSVTTPPPHGKRIPFFKKTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLK 302

Query: 248 HRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQ 307
           HRFDGRISITRVTADISLAKRSVLNNPSK  IIERSNTRSSLAEVQSEIERIFELAR+LQ
Sbjct: 303 HRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQ 362

Query: 308 LVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKL 367
           LV LDADTINHPAQL KTSLAPIIV++K++SPKVLQRLIKSRGKSQSKHLNVQ+ A++KL
Sbjct: 363 LVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKL 422

Query: 368 AQCPP 372
           AQCPP
Sbjct: 423 AQCPP 427


>gi|119943106 synapse-associated protein 102 isoform a [Homo
           sapiens]
          Length = 817

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 61/274 (22%), Positives = 109/274 (39%), Gaps = 29/274 (10%)

Query: 110 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRLENIRIQQEQ 166
           D  +PS  +SF   D LH+    +++WW  RLV    E  +IG IPS  R+E  + +   
Sbjct: 517 DSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEK-KERARL 575

Query: 167 KRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIP-PYDVVPSMRPVVLV 225
           K  +FH       S+     +    + A   +   Q+  +  + P     +   RPV+++
Sbjct: 576 KTVKFHARTGMIESNRDFPGLSDDYYGA--KNLKGQEDAILSYEPVTRQEIHYARPVIIL 633

Query: 226 GPSLKGYEVTDMMQKALFDFLKHRFDGRI-SITRVTAD---------ISLAKRSVLNNPS 275
           GP      + D +   L     H+F   +   TR   D           +++  +  +  
Sbjct: 634 GP------MKDRVNDDLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQ 687

Query: 276 KRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVK 335
               IE      +L    + I+ +  +A   +  +LD    N   +L +  L PI + +K
Sbjct: 688 DNKFIEAGQFNDNL--YGTSIQSVRAVAERGKHCILDVSG-NAIKRLQQAQLYPIAIFIK 744

Query: 336 VSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQ 369
              PK ++ L++   +   +  N     A KL Q
Sbjct: 745 ---PKSIEALMEMNRRQTYEQANKIYDKAMKLEQ 775


>gi|119943108 synapse-associated protein 102 isoform b [Homo
           sapiens]
          Length = 512

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 66/303 (21%), Positives = 118/303 (38%), Gaps = 55/303 (18%)

Query: 110 DVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRLE-------- 158
           D  +PS  +SF   D LH+    +++WW  RLV    E  +IG IPS  R+E        
Sbjct: 180 DSCLPSQGLSFSYGDILHVINASDDEWWQARLVTPHGESEQIGVIPSKKRVEKKERARLK 239

Query: 159 -------------NIRIQQEQKRG-------RFHGGKSSGNSSSSLGEM-VSGTFRATPT 197
                        N  I+ ++K+         F+  K +    SS+ E  V+     + +
Sbjct: 240 TVKFHARTGMIESNRSIKTKRKKSFRLSRKFPFYKSKENMAQESSIQEQGVTSNTSDSES 299

Query: 198 STAKQKQKVTEHIP-PYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRI-S 255
           S+  Q+  +  + P     +   RPV+++GP      + D +   L     H+F   +  
Sbjct: 300 SSKGQEDAILSYEPVTRQEIHYARPVIILGP------MKDRVNDDLISEFPHKFGSCVPH 353

Query: 256 ITRVTAD---------ISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSL 306
            TR   D           +++  +  +      IE      +L    + I+ +  +A   
Sbjct: 354 TTRPRRDNEVDGQDYHFVVSREQMEKDIQDNKFIEAGQFNDNL--YGTSIQSVRAVAERG 411

Query: 307 QLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADK 366
           +  +LD    N   +L +  L PI + +K   PK ++ L++   +   +  N     A K
Sbjct: 412 KHCILDVSG-NAIKRLQQAQLYPIAIFIK---PKSIEALMEMNRRQTYEQANKIYDKAMK 467

Query: 367 LAQ 369
           L Q
Sbjct: 468 LEQ 470


>gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]
          Length = 904

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 31/128 (24%), Positives = 57/128 (44%), Gaps = 10/128 (7%)

Query: 109 EDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRLENIRIQQE 165
           +D  +PS  ++F   D LH+    +++WW  R V    E  E+G IPS  R+E  + +  
Sbjct: 596 KDSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVEK-KERAR 654

Query: 166 QKRGRFHG-GKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSM----- 219
            K  +F+   +  G     +G        +  + +    +   E++  Y+ V        
Sbjct: 655 LKTVKFNSKTRDKGEIPDDMGSKGLKHVTSNASDSESSYRGQEEYVLSYEPVNQQEVNYT 714

Query: 220 RPVVLVGP 227
           RPV+++GP
Sbjct: 715 RPVIILGP 722


>gi|4557529 post-synaptic density protein 95 isoform 1 [Homo
           sapiens]
          Length = 767

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 36/117 (30%), Positives = 52/117 (44%), Gaps = 25/117 (21%)

Query: 115 STAISFDAKDFLHIKEKYNNDWWIGRLV---KEGCEIGFIPSPLRLENIRIQQEQKRGRF 171
           S A+SF   D LH+ +  + +WW  R V    E  +IGFIPS  R+E    ++E  R + 
Sbjct: 492 SQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVE----RREWSRLK- 546

Query: 172 HGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPS 228
              K  G+SS S G   S     T T                  V   RP++++GP+
Sbjct: 547 --AKDWGSSSGSQGREDSVLSYETVTQME---------------VHYARPIIILGPT 586


>gi|192447426 post-synaptic density protein 95 isoform 2 [Homo
           sapiens]
          Length = 721

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 36/117 (30%), Positives = 52/117 (44%), Gaps = 25/117 (21%)

Query: 115 STAISFDAKDFLHIKEKYNNDWWIGRLV---KEGCEIGFIPSPLRLENIRIQQEQKRGRF 171
           S A+SF   D LH+ +  + +WW  R V    E  +IGFIPS  R+E    ++E  R + 
Sbjct: 446 SQALSFRFGDVLHVIDASDEEWWQARRVHSDSETDDIGFIPSKRRVE----RREWSRLK- 500

Query: 172 HGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPS 228
              K  G+SS S G   S     T T                  V   RP++++GP+
Sbjct: 501 --AKDWGSSSGSQGREDSVLSYETVTQME---------------VHYARPIIILGPT 540


>gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]
          Length = 926

 Score = 37.7 bits (86), Expect = 0.022
 Identities = 19/53 (35%), Positives = 29/53 (54%), Gaps = 3/53 (5%)

Query: 109 EDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRLE 158
           +D  +PS  ++F   D LH+    +++WW  R V    E  E+G IPS  R+E
Sbjct: 596 KDSGLPSQGLNFKFGDILHVINASDDEWWQARQVTPDGESDEVGVIPSKRRVE 648


>gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]
          Length = 749

 Score = 37.7 bits (86), Expect = 0.022
 Identities = 34/126 (26%), Positives = 57/126 (45%), Gaps = 13/126 (10%)

Query: 109 EDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRLENIRIQQE 165
           +D  +PS  +SF   D LH+    +++WW  R V    +  E+G IPS  R+E  + +  
Sbjct: 448 KDSGLPSQGLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPSKRRVER-KERAR 506

Query: 166 QKRGRFH---GGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIP-PYDVVPSMRP 221
            K  +F+   G   S      LG+   GT      +   Q+  +  + P     +   RP
Sbjct: 507 LKTVKFNAKPGVIDSKGDIPGLGDDGYGT-----KTLRGQEDLILSYEPVTRQEINYTRP 561

Query: 222 VVLVGP 227
           V+++GP
Sbjct: 562 VIILGP 567


>gi|218156270 chapsyn-110 isoform 4 [Homo sapiens]
          Length = 334

 Score = 37.7 bits (86), Expect = 0.022
 Identities = 34/126 (26%), Positives = 57/126 (45%), Gaps = 13/126 (10%)

Query: 109 EDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRLENIRIQQE 165
           +D  +PS  +SF   D LH+    +++WW  R V    +  E+G IPS  R+E  + +  
Sbjct: 33  KDSGLPSQGLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPSKRRVER-KERAR 91

Query: 166 QKRGRFH---GGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIP-PYDVVPSMRP 221
            K  +F+   G   S      LG+   GT      +   Q+  +  + P     +   RP
Sbjct: 92  LKTVKFNAKPGVIDSKGDIPGLGDDGYGT-----KTLRGQEDLILSYEPVTRQEINYTRP 146

Query: 222 VVLVGP 227
           V+++GP
Sbjct: 147 VIILGP 152


>gi|21361598 membrane protein, palmitoylated 6 [Homo sapiens]
          Length = 540

 Score = 37.4 bits (85), Expect = 0.029
 Identities = 36/140 (25%), Positives = 52/140 (37%), Gaps = 14/140 (10%)

Query: 92  PVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFI 151
           P    VK +  Y    D  +P     + F   + L I  + + +WW    VKEG   G I
Sbjct: 215 PQQVFVKCHFDYNPYNDNLIPCKEAGLKFSKGEILQIVNREDPNWWQASHVKEGGSAGLI 274

Query: 152 PSPLRLENIRIQQEQKRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIP 211
           PS           E+KR  F   +   NS    G + S   +     T +  +     I 
Sbjct: 275 PSQF--------LEEKRKAF-VRRDWDNSGPFCGTISSKKKKKMMYLTTRNAEFDRHEIQ 325

Query: 212 PYDVVPSMRP-----VVLVG 226
            Y+ V  M P     +VL+G
Sbjct: 326 IYEEVAKMPPFQRKTLVLIG 345


>gi|218156338 chapsyn-110 isoform 1 [Homo sapiens]
          Length = 975

 Score = 37.0 bits (84), Expect = 0.037
 Identities = 33/139 (23%), Positives = 59/139 (42%), Gaps = 21/139 (15%)

Query: 109 EDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRLENIRIQQE 165
           +D  +PS  +SF   D LH+    +++WW  R V    +  E+G IPS  R+E  + +  
Sbjct: 656 KDSGLPSQGLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPSKRRVER-KERAR 714

Query: 166 QKRGRFHGGKSSGNSSSSLGEMVSGTF------------RATPTSTAKQKQKVTEHIPPY 213
            K  +F+      +S  S  +    +F              +   T+  ++   + I  Y
Sbjct: 715 LKTVKFNAKPGVIDSKGSFNDKRKKSFIFSRKFPFYKNKEQSEQETSDPERGQEDLILSY 774

Query: 214 DVVPSM-----RPVVLVGP 227
           + V        RPV+++GP
Sbjct: 775 EPVTRQEINYTRPVIILGP 793


>gi|91199538 chapsyn-110 isoform 2 [Homo sapiens]
          Length = 870

 Score = 37.0 bits (84), Expect = 0.037
 Identities = 33/139 (23%), Positives = 59/139 (42%), Gaps = 21/139 (15%)

Query: 109 EDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK---EGCEIGFIPSPLRLENIRIQQE 165
           +D  +PS  +SF   D LH+    +++WW  R V    +  E+G IPS  R+E  + +  
Sbjct: 551 KDSGLPSQGLSFKYGDILHVINASDDEWWQARRVMLEGDSEEMGVIPSKRRVER-KERAR 609

Query: 166 QKRGRFHGGKSSGNSSSSLGEMVSGTF------------RATPTSTAKQKQKVTEHIPPY 213
            K  +F+      +S  S  +    +F              +   T+  ++   + I  Y
Sbjct: 610 LKTVKFNAKPGVIDSKGSFNDKRKKSFIFSRKFPFYKNKEQSEQETSDPERGQEDLILSY 669

Query: 214 DVVPSM-----RPVVLVGP 227
           + V        RPV+++GP
Sbjct: 670 EPVTRQEINYTRPVIILGP 688


>gi|38570142 membrane protein, palmitoylated 5 [Homo sapiens]
          Length = 675

 Score = 36.2 bits (82), Expect = 0.064
 Identities = 63/292 (21%), Positives = 113/292 (38%), Gaps = 36/292 (12%)

Query: 84  QLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVK 143
           Q++   +K     VK +  Y  + D  VP     +SF   D LH+  + + +WW  +  +
Sbjct: 337 QIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWW--QAYR 394

Query: 144 EGCE-----IGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNSSSSLGEMVSGTFRATPTS 198
           EG E      G +P     ++ + Q+E  +      K    S        +   R     
Sbjct: 395 EGDEDNQPLAGLVPG----KSFQQQREAMKQTIEEDKEPEKSGKLWCAKKNKKKRKKVLY 450

Query: 199 TA-KQKQKVTEHIPPYDVVP-------SMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRF 250
            A K      E I  Y+ +          RP++L+GP   G    + +++ L +  K RF
Sbjct: 451 NANKNDDYDNEEILTYEEMSLYHQPANRKRPIILIGPQNCG---QNELRQRLMNKEKDRF 507

Query: 251 DGRI-SITRVTADISLAKRSVLNNPSKRA---------IIERSNTRSSLAEVQSEIERIF 300
              +   TR   D  +A R   +  S++A          IE      +L    + I+ + 
Sbjct: 508 ASAVPHTTRSRRDQEVAGRD-YHFVSRQAFEADIAAGKFIEHGEFEKNL--YGTSIDSVR 564

Query: 301 ELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKS 352
           ++  S ++ +L   T      L  + L P I+ +   S + L+ L+   GK+
Sbjct: 565 QVINSGKICLLSLRT-QSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKN 615


>gi|186700629 calcium/calmodulin-dependent serine protein kinase
           isoform 3 [Homo sapiens]
          Length = 897

 Score = 35.8 bits (81), Expect = 0.083
 Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 1/59 (1%)

Query: 97  VKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLV-KEGCEIGFIPSP 154
           V+    Y  A D+ +P     I F   D + I  K +++WW G+L   +    G IPSP
Sbjct: 588 VRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSP 646


>gi|186700627 calcium/calmodulin-dependent serine protein kinase
           isoform 2 [Homo sapiens]
          Length = 898

 Score = 35.8 bits (81), Expect = 0.083
 Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 1/59 (1%)

Query: 97  VKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLV-KEGCEIGFIPSP 154
           V+    Y  A D+ +P     I F   D + I  K +++WW G+L   +    G IPSP
Sbjct: 594 VRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSP 652


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.127    0.356 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,933,196
Number of Sequences: 37866
Number of extensions: 725771
Number of successful extensions: 3110
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 41
Number of HSP's successfully gapped in prelim test: 42
Number of HSP's that attempted gapping in prelim test: 2986
Number of HSP's gapped (non-prelim): 136
length of query: 458
length of database: 18,247,518
effective HSP length: 106
effective length of query: 352
effective length of database: 14,233,722
effective search space: 5010270144
effective search space used: 5010270144
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.