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Search of human proteins with 22035550
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22035550 amyloid beta A4 precursor protein-binding, family
A, member 2 isoform a [Homo sapiens]
(749 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22035550 amyloid beta A4 precursor protein-binding, family A,... 1521 0.0
gi|194353992 amyloid beta A4 precursor protein-binding, family A... 1490 0.0
gi|22035548 amyloid beta A4 precursor protein-binding, family A,... 719 0.0
gi|11342678 amyloid beta (A4) precursor protein-binding, family ... 479 e-135
gi|55749523 syntenin isoform 3 [Homo sapiens] 61 4e-09
gi|55749515 syntenin isoform 3 [Homo sapiens] 61 4e-09
gi|55749504 syntenin isoform 2 [Homo sapiens] 61 4e-09
gi|55749490 syntenin isoform 1 [Homo sapiens] 61 4e-09
gi|56243522 syntenin isoform 1 [Homo sapiens] 61 4e-09
gi|134152672 syndecan binding protein 2 isoform a [Homo sapiens] 58 3e-08
gi|38016916 syndecan binding protein 2 isoform b [Homo sapiens] 58 3e-08
gi|112382257 InaD-like [Homo sapiens] 55 2e-07
gi|148746189 multiple PDZ domain protein [Homo sapiens] 55 2e-07
gi|4557529 post-synaptic density protein 95 isoform 1 [Homo sapi... 53 9e-07
gi|192447426 post-synaptic density protein 95 isoform 2 [Homo sa... 53 9e-07
gi|223890252 glutamate receptor interacting protein 1 [Homo sapi... 52 3e-06
gi|119943106 synapse-associated protein 102 isoform a [Homo sapi... 52 3e-06
gi|222446609 rai-like protein [Homo sapiens] 51 4e-06
gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens] 50 6e-06
gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens] 50 6e-06
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 50 6e-06
gi|218156340 chapsyn-110 isoform 3 [Homo sapiens] 50 8e-06
gi|218156338 chapsyn-110 isoform 1 [Homo sapiens] 50 8e-06
gi|91199538 chapsyn-110 isoform 2 [Homo sapiens] 50 8e-06
gi|38570142 membrane protein, palmitoylated 5 [Homo sapiens] 48 3e-05
gi|169212742 PREDICTED: similar to hCG1654128 [Homo sapiens] 47 5e-05
gi|10835173 nitric oxide synthase 1, neuronal [Homo sapiens] 46 1e-04
gi|169213065 PREDICTED: similar to hCG1654128 [Homo sapiens] 46 1e-04
gi|122937249 glutamate receptor interacting protein 2 [Homo sapi... 46 1e-04
gi|45827729 scribble isoform b [Homo sapiens] 46 1e-04
>gi|22035550 amyloid beta A4 precursor protein-binding, family A,
member 2 isoform a [Homo sapiens]
Length = 749
Score = 1521 bits (3937), Expect = 0.0
Identities = 749/749 (100%), Positives = 749/749 (100%)
Query: 1 MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE 60
MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE
Sbjct: 1 MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE 60
Query: 61 QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE 120
QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE
Sbjct: 61 QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE 120
Query: 121 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ 180
YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ
Sbjct: 121 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ 180
Query: 181 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT 240
EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT
Sbjct: 181 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT 240
Query: 241 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF 300
SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF
Sbjct: 241 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF 300
Query: 301 KPKTRTPEERLKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP 360
KPKTRTPEERLKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP
Sbjct: 301 KPKTRTPEERLKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP 360
Query: 361 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSE 420
CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSE
Sbjct: 361 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSE 420
Query: 421 GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS 480
GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS
Sbjct: 421 GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS 480
Query: 481 QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ 540
QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ
Sbjct: 481 QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ 540
Query: 541 KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM 600
KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM
Sbjct: 541 KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM 600
Query: 601 MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV 660
MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV
Sbjct: 601 MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV 660
Query: 661 LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL 720
LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL
Sbjct: 661 LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL 720
Query: 721 SNSVGEIHMKTMPAAMFRLLTGQETPLYI 749
SNSVGEIHMKTMPAAMFRLLTGQETPLYI
Sbjct: 721 SNSVGEIHMKTMPAAMFRLLTGQETPLYI 749
>gi|194353992 amyloid beta A4 precursor protein-binding, family A,
member 2 isoform b [Homo sapiens]
Length = 737
Score = 1490 bits (3858), Expect = 0.0
Identities = 737/749 (98%), Positives = 737/749 (98%), Gaps = 12/749 (1%)
Query: 1 MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE 60
MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE
Sbjct: 1 MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE 60
Query: 61 QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE 120
QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE
Sbjct: 61 QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE 120
Query: 121 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ 180
YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ
Sbjct: 121 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ 180
Query: 181 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT 240
EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT
Sbjct: 181 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT 240
Query: 241 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF 300
SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF
Sbjct: 241 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF 300
Query: 301 KPKTRTPEERLKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP 360
KPKTRTPEERLKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP
Sbjct: 301 KPKTRTPEERLKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP 360
Query: 361 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSE 420
CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVK NSE
Sbjct: 361 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVK------------NSE 408
Query: 421 GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS 480
GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS
Sbjct: 409 GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS 468
Query: 481 QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ 540
QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ
Sbjct: 469 QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ 528
Query: 541 KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM 600
KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM
Sbjct: 529 KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM 588
Query: 601 MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV 660
MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV
Sbjct: 589 MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV 648
Query: 661 LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL 720
LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL
Sbjct: 649 LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL 708
Query: 721 SNSVGEIHMKTMPAAMFRLLTGQETPLYI 749
SNSVGEIHMKTMPAAMFRLLTGQETPLYI
Sbjct: 709 SNSVGEIHMKTMPAAMFRLLTGQETPLYI 737
>gi|22035548 amyloid beta A4 precursor protein-binding, family A,
member 1 [Homo sapiens]
Length = 837
Score = 719 bits (1855), Expect = 0.0
Identities = 433/814 (53%), Positives = 520/814 (63%), Gaps = 101/814 (12%)
Query: 28 EPESEDMELPLE----GYVPEGLELAALRPESPAPEEQ--ECHNHSPDGDSSSDYVNNTS 81
E E E + P + G G L LR + EE+ EC S +S +T+
Sbjct: 33 EVEEEQQQPPQQQHYVGRHQRGRALEDLRAQLGQEEEERGECLARSASTESGFHNHTDTA 92
Query: 82 E-------EEDYD-EGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEEYLAHSA------- 126
E + YD E + E+ Y ++Y PE + Y E + E A
Sbjct: 93 EGDVIAAARDGYDAERAQDPEDESAYAVQYRPEAEEYTEQAEAEHAEATHRRALPNHLHF 152
Query: 127 HPVDTDECQEAV--------------------EEWTDSAGPHPHGHEAEGSQDYPDGQ-- 164
H ++ +E A E + D G H +E G D +
Sbjct: 153 HSLEHEEAMNAAYSGYVYTHRLFHRGEDEPYSEPYADYGGLQEHVYEEIGDAPELDARDG 212
Query: 165 LPIPEDEPSVLEAHDQEEDG----HYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLE 220
L + E E A+ QE G HY +G D +EA +PY D
Sbjct: 213 LRLYEQERDEAAAYRQEALGARLHHYDERSDGESDSPEKEAE----FAPYPRM----DSY 264
Query: 221 DQEEDIDQIVAEIKMSLSMTSITSASEASPEHGPE----PGPEDSVEACPPIKASC---- 272
+QEEDIDQIVAE+K S+S S+ A+E PE + P P P ++A
Sbjct: 265 EQEEDIDQIVAEVKQSMSSQSLDKAAEDMPEAEQDLERPPTPAGGRPDSPGLQAPAGQQR 324
Query: 273 --------------SPSRHEARPKSLNLLPEA---------KHPGDPQRGFKP------- 302
S + +A ++ + EA + P P +P
Sbjct: 325 AVGPAGGGEAGQRYSKEKRDAISLAIKDIKEAIEEVKTRTIRSPYTPDEPKEPIWVMRQD 384
Query: 303 --KTRTPEERLKWPHEQVCNGLEQPRKQQRSDLN----GPVDNNNIPETKK-VASFPSFV 355
TR +++ + G P + S + PV+ + E++K +ASFP++V
Sbjct: 385 ISPTRDCDDQRPMDGDSPSPGSSSPLGAESSSTSLHPSDPVEASTNKESRKSLASFPTYV 444
Query: 356 AVPGPCEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKK 415
VPGPC+PEDLIDGIIFAANYLGSTQLLS++ PSKN+RMMQAQEAVSR+K QK AK +K
Sbjct: 445 EVPGPCDPEDLIDGIIFAANYLGSTQLLSDKTPSKNVRMMQAQEAVSRIKMAQKLAKSRK 504
Query: 416 KANSEGDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRM 475
KA EG++Q +TEVDLFISTQRIKVLNADTQETMMDH LRTISYIADIGNIVVLMARRRM
Sbjct: 505 KA-PEGESQPMTEVDLFISTQRIKVLNADTQETMMDHPLRTISYIADIGNIVVLMARRRM 563
Query: 476 PRSASQDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINP 535
PRS SQ+ +E + +Q+GK+QYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINP
Sbjct: 564 PRSNSQENVEASHPSQDGKRQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINP 623
Query: 536 EDLSQKEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTV 595
EDLSQKEYSD++NTQ+MYNDDLIHFS SENCK++ +EK KGEILGVV+VESGWGSILPTV
Sbjct: 624 EDLSQKEYSDLLNTQDMYNDDLIHFSKSENCKDVFIEKQKGEILGVVIVESGWGSILPTV 683
Query: 596 ILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCP 655
I+ANMM+GGPA +SGKL+IGDQIMSINGTSLVGLPL+TCQ IIKGLKNQ++VKLNIV CP
Sbjct: 684 IIANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLPLSTCQSIIKGLKNQSRVKLNIVRCP 743
Query: 656 PVTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEK 715
PVTTVLI+RPDL+YQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVAT HEK
Sbjct: 744 PVTTVLIRRPDLRYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATPHEK 803
Query: 716 IVQALSNSVGEIHMKTMPAAMFRLLTGQETPLYI 749
IV LSN+VGEIHMKTMPAAM+RLLT QE P+YI
Sbjct: 804 IVHILSNAVGEIHMKTMPAAMYRLLTAQEQPVYI 837
>gi|11342678 amyloid beta (A4) precursor protein-binding, family A,
member 3 [Homo sapiens]
Length = 575
Score = 479 bits (1234), Expect = e-135
Identities = 246/408 (60%), Positives = 310/408 (75%), Gaps = 27/408 (6%)
Query: 343 PETKKVASFPSFVAVPGPCEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVS 402
PET +AS+P+ VPGPC+ EDL+DG+IF A YLGSTQL+SERNP + RM QA+EA+
Sbjct: 194 PET--LASYPAPQEVPGPCDHEDLLDGVIFGARYLGSTQLVSERNPPTSTRMAQAREAMD 251
Query: 403 RVKRMQKAAKIKKKANSEGDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIAD 462
RVK +G+ Q +TEVDLF+ST+RIKVL AD+QE MMDHAL TISY AD
Sbjct: 252 RVKA------------PDGETQPMTEVDLFVSTKRIKVLTADSQEAMMDHALHTISYTAD 299
Query: 463 IGNIVVLMARRRMPRS-ASQDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFS 521
IG ++VLMARRR+ R A QD G++ YKM+CHVF +EDAQLIAQ+IGQAF+
Sbjct: 300 IGCVLVLMARRRLARRPAPQD---------HGRRLYKMLCHVFYAEDAQLIAQAIGQAFA 350
Query: 522 VAYQEFLRANGINPEDLSQKEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGV 581
AY +FLR +GI+P SQ ++N DL HFSNS+NC+E+ LEK +GE LGV
Sbjct: 351 AAYSQFLRESGIDP---SQVGVHPSPGACHLHNGDLDHFSNSDNCREVHLEKRRGEGLGV 407
Query: 582 VVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGL 641
+VESGWGS+LPT ++AN+++GGPA RSG LSIGD++ +INGTSLVGLPLA CQ ++
Sbjct: 408 ALVESGWGSLLPTAVIANLLHGGPAERSGALSIGDRLTAINGTSLVGLPLAACQAAVRET 467
Query: 642 KNQTQVKLNIVSCPPVTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRII 701
K+QT V L+IV CPPVTT +I RP + QLGF V++GIICSL+RGGIAERGG+RVGHRII
Sbjct: 468 KSQTSVTLSIVHCPPVTTAIIHRPHAREQLGFCVEDGIICSLLRGGIAERGGIRVGHRII 527
Query: 702 EINGQSVVATAHEKIVQALSNSVGEIHMKTMPAAMFRLLTGQETPLYI 749
EINGQSVVAT H +I++ L+ + GE+H+KTMPAA +RLLTGQE P+Y+
Sbjct: 528 EINGQSVVATPHARIIELLTEAYGEVHIKTMPAATYRLLTGQEQPVYL 575
>gi|55749523 syntenin isoform 3 [Homo sapiens]
Length = 297
Score = 60.8 bits (146), Expect = 4e-09
Identities = 42/142 (29%), Positives = 69/142 (48%), Gaps = 3/142 (2%)
Query: 605 PAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKR 664
PA+ G L GDQ++ ING + G ++K + ++ + I P T+ + +
Sbjct: 145 PASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGE-KITMTIRDRPFERTITMHK 202
Query: 665 PDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSV 724
D +GF +NG I S+++ A R G+ H I EINGQ+V+ +I LS S
Sbjct: 203 -DSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADILSTSG 261
Query: 725 GEIHMKTMPAAMFRLLTGQETP 746
+ + MPA +F + + P
Sbjct: 262 TVVTITIMPAFIFEHIIKRMAP 283
>gi|55749515 syntenin isoform 3 [Homo sapiens]
Length = 297
Score = 60.8 bits (146), Expect = 4e-09
Identities = 42/142 (29%), Positives = 69/142 (48%), Gaps = 3/142 (2%)
Query: 605 PAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKR 664
PA+ G L GDQ++ ING + G ++K + ++ + I P T+ + +
Sbjct: 145 PASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGE-KITMTIRDRPFERTITMHK 202
Query: 665 PDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSV 724
D +GF +NG I S+++ A R G+ H I EINGQ+V+ +I LS S
Sbjct: 203 -DSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADILSTSG 261
Query: 725 GEIHMKTMPAAMFRLLTGQETP 746
+ + MPA +F + + P
Sbjct: 262 TVVTITIMPAFIFEHIIKRMAP 283
>gi|55749504 syntenin isoform 2 [Homo sapiens]
Length = 292
Score = 60.8 bits (146), Expect = 4e-09
Identities = 42/142 (29%), Positives = 69/142 (48%), Gaps = 3/142 (2%)
Query: 605 PAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKR 664
PA+ G L GDQ++ ING + G ++K + ++ + I P T+ + +
Sbjct: 140 PASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGE-KITMTIRDRPFERTITMHK 197
Query: 665 PDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSV 724
D +GF +NG I S+++ A R G+ H I EINGQ+V+ +I LS S
Sbjct: 198 -DSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADILSTSG 256
Query: 725 GEIHMKTMPAAMFRLLTGQETP 746
+ + MPA +F + + P
Sbjct: 257 TVVTITIMPAFIFEHIIKRMAP 278
>gi|55749490 syntenin isoform 1 [Homo sapiens]
Length = 298
Score = 60.8 bits (146), Expect = 4e-09
Identities = 42/142 (29%), Positives = 69/142 (48%), Gaps = 3/142 (2%)
Query: 605 PAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKR 664
PA+ G L GDQ++ ING + G ++K + ++ + I P T+ + +
Sbjct: 146 PASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGE-KITMTIRDRPFERTITMHK 203
Query: 665 PDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSV 724
D +GF +NG I S+++ A R G+ H I EINGQ+V+ +I LS S
Sbjct: 204 -DSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADILSTSG 262
Query: 725 GEIHMKTMPAAMFRLLTGQETP 746
+ + MPA +F + + P
Sbjct: 263 TVVTITIMPAFIFEHIIKRMAP 284
>gi|56243522 syntenin isoform 1 [Homo sapiens]
Length = 298
Score = 60.8 bits (146), Expect = 4e-09
Identities = 42/142 (29%), Positives = 69/142 (48%), Gaps = 3/142 (2%)
Query: 605 PAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKR 664
PA+ G L GDQ++ ING + G ++K + ++ + I P T+ + +
Sbjct: 146 PASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGE-KITMTIRDRPFERTITMHK 203
Query: 665 PDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSV 724
D +GF +NG I S+++ A R G+ H I EINGQ+V+ +I LS S
Sbjct: 204 -DSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADILSTSG 262
Query: 725 GEIHMKTMPAAMFRLLTGQETP 746
+ + MPA +F + + P
Sbjct: 263 TVVTITIMPAFIFEHIIKRMAP 284
>gi|134152672 syndecan binding protein 2 isoform a [Homo sapiens]
Length = 292
Score = 58.2 bits (139), Expect = 3e-08
Identities = 35/145 (24%), Positives = 69/145 (47%), Gaps = 3/145 (2%)
Query: 605 PAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKR 664
PA+ G L GDQ++ I+G G ++K V +V P +
Sbjct: 140 PASLVG-LRFGDQLLQIDGRDCAGWSSHKAHQVVKKASGDKIVV--VVRDRPFQRTVTMH 196
Query: 665 PDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSV 724
D +GF ++ G I SL++G A R G+ H + E++GQ+V+ +KI++ L+ +
Sbjct: 197 KDSMGHVGFVIKKGKIVSLVKGSSAARNGLLTNHYVCEVDGQNVIGLKDKKIMEILATAG 256
Query: 725 GEIHMKTMPAAMFRLLTGQETPLYI 749
+ + +P+ ++ + + P+ +
Sbjct: 257 NVVTLTIIPSVIYEHMVKKLPPVLL 281
>gi|38016916 syndecan binding protein 2 isoform b [Homo sapiens]
Length = 207
Score = 58.2 bits (139), Expect = 3e-08
Identities = 35/145 (24%), Positives = 69/145 (47%), Gaps = 3/145 (2%)
Query: 605 PAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKR 664
PA+ G L GDQ++ I+G G ++K V +V P +
Sbjct: 55 PASLVG-LRFGDQLLQIDGRDCAGWSSHKAHQVVKKASGDKIVV--VVRDRPFQRTVTMH 111
Query: 665 PDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSV 724
D +GF ++ G I SL++G A R G+ H + E++GQ+V+ +KI++ L+ +
Sbjct: 112 KDSMGHVGFVIKKGKIVSLVKGSSAARNGLLTNHYVCEVDGQNVIGLKDKKIMEILATAG 171
Query: 725 GEIHMKTMPAAMFRLLTGQETPLYI 749
+ + +P+ ++ + + P+ +
Sbjct: 172 NVVTLTIIPSVIYEHMVKKLPPVLL 196
>gi|112382257 InaD-like [Homo sapiens]
Length = 1801
Score = 55.5 bits (132), Expect = 2e-07
Identities = 65/283 (22%), Positives = 110/283 (38%), Gaps = 77/283 (27%)
Query: 523 AYQEFLRANGINPEDLSQKEYSDIINTQE------MYNDDLIHFSNSENCK--ELQLEKH 574
A + L NG++ + S +E + +Y D+ H+ + EN + + L+K
Sbjct: 1481 AGDQILEVNGVDLRNSSHEEAITALRQTPQKVRLVVYRDEA-HYRDEENLEIFPVDLQKK 1539
Query: 575 KGEILGVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATC 634
G LG+ +V GS V +++++ GG A G+L GDQI+S+NG + T
Sbjct: 1540 AGRGLGLSIVGKRNGS---GVFISDIVKGGAADLDGRLIQGDQILSVNGEDMRNASQETV 1596
Query: 635 QGIIKGLKNQTQVKLNIV------------------------SCPP------------VT 658
I+K + Q+++ + SC P V
Sbjct: 1597 ATILKCAQGLVQLEIGRLRAGSWTSARTTSQNSQGSQQSAHSSCHPSFAPVITGLQNLVG 1656
Query: 659 TVLIKRP------------------DLKYQLGFSVQNG----------IICSLMRGGIAE 690
T + P +L LG S+ G I + G+A
Sbjct: 1657 TKRVSDPSQKNSGTDMEPRTVEINRELSDALGISIAGGRGSPLGDIPVFIAMIQASGVAA 1716
Query: 691 R-GGVRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMKTM 732
R ++VG RI+ INGQ + +H +V L N+ G I ++ +
Sbjct: 1717 RTQKLKVGDRIVSINGQPLDGLSHADVVNLLKNAYGRIILQVV 1759
Score = 43.5 bits (101), Expect = 7e-04
Identities = 49/182 (26%), Positives = 89/182 (48%), Gaps = 23/182 (12%)
Query: 567 KELQLEKHKGEI-LGVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTS 625
+E+ +E KG LG+ +V G + L +++ + G AAR G+L GDQI+ +NG
Sbjct: 1434 QEMIIEISKGRSGLGLSIV-GGKDTPLNAIVIHEVYEEGAAARDGRLWAGDQILEVNG-- 1490
Query: 626 LVGLPLATCQGIIKGLKNQTQVKLNIV------SCPPVTTVLIKRPDLKYQ----LGFSV 675
V L ++ + I L+ QT K+ +V + I DL+ + LG S+
Sbjct: 1491 -VDLRNSSHEEAITALR-QTPQKVRLVVYRDEAHYRDEENLEIFPVDLQKKAGRGLGLSI 1548
Query: 676 ---QNG---IICSLMRGGIAERGGVRV-GHRIIEINGQSVVATAHEKIVQALSNSVGEIH 728
+NG I +++GG A+ G + G +I+ +NG+ + + E + L + G +
Sbjct: 1549 VGKRNGSGVFISDIVKGGAADLDGRLIQGDQILSVNGEDMRNASQETVATILKCAQGLVQ 1608
Query: 729 MK 730
++
Sbjct: 1609 LE 1610
Score = 41.2 bits (95), Expect = 0.004
Identities = 31/110 (28%), Positives = 57/110 (51%), Gaps = 7/110 (6%)
Query: 567 KELQLEKHKGEILGVVVVESGWGSILPT--VILANMMNGGPAARSGKLSIGDQIMSINGT 624
+ +++ + + LG+ + G GS L V +A + G AAR+ KL +GD+I+SING
Sbjct: 1675 RTVEINRELSDALGISIA-GGRGSPLGDIPVFIAMIQASGVAARTQKLKVGDRIVSINGQ 1733
Query: 625 SLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKRPDLK--YQLG 672
L GL A ++K ++ L +V+ ++ + + ++ Y LG
Sbjct: 1734 PLDGLSHADVVNLLKNAYG--RIILQVVADTNISAIAAQLENMSTGYHLG 1781
Score = 37.4 bits (85), Expect = 0.051
Identities = 39/179 (21%), Positives = 73/179 (40%), Gaps = 45/179 (25%)
Query: 595 VILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKL----- 649
V++ ++ GG A R G+L GD I+ I GT++ G+ +++ N ++ +
Sbjct: 270 VVVRTIVPGGLADRDGRLQTGDHILKIGGTNVQGMTSEQVAQVLRNCGNSVRMLVARDPA 329
Query: 650 -NIVSCPP--------VTTVLIKRPDLKYQLGFSVQN-----------GI---------- 679
+I PP + TV K P L F N GI
Sbjct: 330 GDISVTPPAPAALPVALPTVASKGPGSDSSL-FETYNVELVRKDGQSLGIRIVGYVGTSH 388
Query: 680 --------ICSLMRGGIA-ERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHM 729
+ S++ G A G ++V +I+ ++G ++ A+ +V+ L N+ +H+
Sbjct: 389 TGEASGIYVKSIIPGSAAYHNGHIQVNDKIVAVDGVNIQGFANHDVVEVLRNAGQVVHL 447
Score = 32.7 bits (73), Expect = 1.3
Identities = 15/36 (41%), Positives = 20/36 (55%)
Query: 604 GPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIK 639
GPAA G++ IGD+++ IN L G IIK
Sbjct: 1273 GPAAADGRMRIGDELLEINNQILYGRSHQNASAIIK 1308
Score = 32.0 bits (71), Expect = 2.2
Identities = 24/95 (25%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
Query: 547 INTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANMMNGGPA 606
+NT+E + +L +S EL ++ KG ++ + +++ +++ G A
Sbjct: 667 VNTEEDDDGELALWSPEVKIVEL-VKDCKGLGFSILDYQDPLDPTRSVIVIRSLVADGVA 725
Query: 607 ARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGL 641
RSG L GD+++S+N L LA I+K +
Sbjct: 726 ERSGGLLPGDRLVSVNEYCLDNTSLAEAVEILKAV 760
>gi|148746189 multiple PDZ domain protein [Homo sapiens]
Length = 2041
Score = 55.1 bits (131), Expect = 2e-07
Identities = 70/262 (26%), Positives = 113/262 (43%), Gaps = 31/262 (11%)
Query: 494 KKQYKMICHVFESEDAQLIAQSIGQAFSV---AYQEFLRANGINPEDLSQKEYSDIINTQ 550
K K+ H E+ D+Q + + G A + Q + +PE S + S +T
Sbjct: 1553 KMTVKLTIHA-ENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRS-STP 1610
Query: 551 EMYNDDLIHFSNSENCKELQLEKHKGEI-LGVVVVESGWGSILPTVILANMMNGGPAARS 609
++ D C E +E KG LG+ +V G ++L +I+ + G A +
Sbjct: 1611 AIFASDPATCPIIPGC-ETTIEISKGRTGLGLSIV-GGSDTLLGAIIIHEVYEEGAACKD 1668
Query: 610 GKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQ-VKLNIVS----------CPPVT 658
G+L GDQI+ +NG + L AT I L+ Q V+L + C +T
Sbjct: 1669 GRLWAGDQILEVNG---IDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLT 1725
Query: 659 TVLIKRPDLKYQLGFSV-----QNGIICS-LMRGGIAERGG-VRVGHRIIEINGQSVVAT 711
L K+P LG S+ G+ S +++GGIA+ G + G +I+ +NG+ V
Sbjct: 1726 IELQKKPG--KGLGLSIVGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNA 1783
Query: 712 AHEKIVQALSNSVGEIHMKTMP 733
E + L S G + T P
Sbjct: 1784 TQEAVAALLKVSEGSLSSFTFP 1805
Score = 53.1 bits (126), Expect = 9e-07
Identities = 66/265 (24%), Positives = 110/265 (41%), Gaps = 52/265 (19%)
Query: 523 AYQEFLRANGINPEDLSQKEYSDIINTQE---------MYNDDLIHFSNSENCKEL--QL 571
A + L NGI DL + + + IN +Y D+ + E C L +L
Sbjct: 1673 AGDQILEVNGI---DLRKATHDEAINVLRQTPQRVRLTLYRDEA-PYKEEEVCDTLTIEL 1728
Query: 572 EKHKGEILGVVVVESGWGSILPT-VILANMMNGGPAARSGKLSIGDQIMSINGTSL---- 626
+K G+ LG+ +V G T V +++++ GG A G+L GDQI+ +NG +
Sbjct: 1729 QKKPGKGLGLSIV----GKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNAT 1784
Query: 627 ---VGLPLATCQGII-------------KGLKNQTQVKLNIVSCPPVTTVLIKRPDLKYQ 670
V L +G + + L++ ++ + TV +K+
Sbjct: 1785 QEAVAALLKVSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGLRTVEMKKGPTD-S 1843
Query: 671 LGFSVQNG---------IICSLMR--GGIAERGGVRVGHRIIEINGQSVVATAHEKIVQA 719
LG S+ G I ++M G A+ +RVG RI+ I G S H + V
Sbjct: 1844 LGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTSTEGMTHTQAVNL 1903
Query: 720 LSNSVGEIHMKTMPAAMFRLLTGQE 744
L N+ G I M+ + ++TG +
Sbjct: 1904 LKNASGSIEMQVVAGGDVSVVTGHQ 1928
Score = 52.8 bits (125), Expect = 1e-06
Identities = 37/118 (31%), Positives = 61/118 (51%), Gaps = 10/118 (8%)
Query: 534 NPEDLSQKEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILP 593
N E+L KE + T +D + S+ +N + L+L K +G LG+ + E L
Sbjct: 1453 NSENLQNKETEPTVTT----SDAAVDLSSFKNVQHLELPKDQGG-LGIAISEE---DTLS 1504
Query: 594 TVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNI 651
VI+ ++ G AA G+L +GDQI++++ +VG P+ ++K K VKL I
Sbjct: 1505 GVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAK--MTVKLTI 1560
Score = 50.1 bits (118), Expect = 8e-06
Identities = 50/216 (23%), Positives = 92/216 (42%), Gaps = 45/216 (20%)
Query: 561 SNSENCKELQLEKHKGEILGVVVVESGWGSILPTV--ILANMMNGGPAARSGKLSIGDQI 618
S + + ++++K + LG+ + G GS L V +A M G AA++ KL +GD+I
Sbjct: 1826 SEIQGLRTVEMKKGPTDSLGISIA-GGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRI 1884
Query: 619 MSINGTSLVGLPLATCQGIIKGLKNQTQVKL------------------NIVSCPPVTTV 660
++I GTS G+ ++K ++++ + +S +T+
Sbjct: 1885 VTICGTSTEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSS 1944
Query: 661 LIKRPDL-------------KYQLGFSVQNG-----------IICSLMRGGIAERGGVRV 696
I + DL LGFS+ G + +G +E G ++
Sbjct: 1945 SIFQDDLGPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKR 2004
Query: 697 GHRIIEINGQSVVATAHEKIVQALSNSVGEIHMKTM 732
G +II +NGQS+ HE+ V L + G + + +
Sbjct: 2005 GDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLMVL 2040
Score = 39.3 bits (90), Expect = 0.014
Identities = 31/99 (31%), Positives = 50/99 (50%), Gaps = 10/99 (10%)
Query: 547 INTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSI---LPTVILANMMNG 603
+ + ++ DDL CK + LE+ + LG +V G+GS LP + + +
Sbjct: 1941 LTSSSIFQDDL----GPPQCKSITLERGP-DGLGFSIV-GGYGSPHGDLP-IYVKTVFAK 1993
Query: 604 GPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLK 642
G A+ G+L GDQI+++NG SL G+ I+K K
Sbjct: 1994 GAASEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTK 2032
Score = 36.2 bits (82), Expect = 0.11
Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 12/90 (13%)
Query: 586 SGWGSILPTVI----LANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGL 641
SG G L + + +++ GP SGKL GD+++ +NG +L+G Q ++ L
Sbjct: 563 SGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELLEVNGITLLG---ENHQDVVNIL 619
Query: 642 KNQTQVKLNIVSC----PPVTTVLIKRPDL 667
K + +++ +V C PP T + DL
Sbjct: 620 K-ELPIEVTMVCCRRTVPPTTQSELDSLDL 648
Score = 34.7 bits (78), Expect = 0.33
Identities = 14/45 (31%), Positives = 31/45 (68%)
Query: 595 VILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIK 639
+I+ ++++GG +R G+++IGD I+SIN S + + A + +++
Sbjct: 1031 MIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLR 1075
Score = 33.1 bits (74), Expect = 0.97
Identities = 18/74 (24%), Positives = 39/74 (52%), Gaps = 7/74 (9%)
Query: 560 FSNSENCKELQLEKHKGEILGVVVVES-GWGS------ILPTVILANMMNGGPAARSGKL 612
+SN + ++L + + LG+ +V G GS ++ + + +++ PA ++G L
Sbjct: 1143 YSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNGTL 1202
Query: 613 SIGDQIMSINGTSL 626
GD+I+ ++G L
Sbjct: 1203 KPGDRIVEVDGMDL 1216
Score = 32.3 bits (72), Expect = 1.7
Identities = 41/188 (21%), Positives = 74/188 (39%), Gaps = 48/188 (25%)
Query: 595 VILANMMNGGPAARSGKLSIGDQIMSINGTSLVGL----------------PLATCQGII 638
VI+ ++ GG A + G+L GD I+ I T L G+ L +G I
Sbjct: 279 VIVKTILPGGVADQHGRLCSGDHILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAI 338
Query: 639 KGLKNQTQVKLNIVSCPPVTTVLIKRPDLKYQLG-----FSVQ----------------- 676
+ T + + + S P T L R D Q G F V+
Sbjct: 339 EERTAPTALGITLSSSPTSTPEL--RVDASTQKGEESETFDVELTKNVQGLGITIAGYIG 396
Query: 677 ------NGI-ICSLMRGGIAERGG-VRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIH 728
+GI + S+ + E G +++G +II ++G ++ +++ V+ L ++ +
Sbjct: 397 DKKLEPSGIFVKSITKSSAVEHDGRIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVL 456
Query: 729 MKTMPAAM 736
+ M M
Sbjct: 457 LTLMRRGM 464
Score = 32.3 bits (72), Expect = 1.7
Identities = 22/93 (23%), Positives = 46/93 (49%), Gaps = 2/93 (2%)
Query: 567 KELQLEK-HKGEILGVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTS 625
+ ++LEK KG ++ + +I+ +++ GG A + G+L GD++M +N +
Sbjct: 699 QHIELEKGSKGLGFSILDYQDPIDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVN 758
Query: 626 LVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVT 658
L L +KG + T V++ + P++
Sbjct: 759 LENSSLEEAVEALKGAPSGT-VRIGVAKPLPLS 790
Score = 32.0 bits (71), Expect = 2.2
Identities = 15/54 (27%), Positives = 27/54 (50%)
Query: 594 TVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQV 647
+V + + G A + G+L I D+++ ING L G IIK ++ ++
Sbjct: 1374 SVFIVGIDPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKI 1427
>gi|4557529 post-synaptic density protein 95 isoform 1 [Homo
sapiens]
Length = 767
Score = 53.1 bits (126), Expect = 9e-07
Identities = 42/157 (26%), Positives = 76/157 (48%), Gaps = 25/157 (15%)
Query: 593 PTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQ-TQVKLNI 651
P++ + ++ GG AA+ G+L + D I+ +N V + T ++ LK + V+L +
Sbjct: 135 PSIFITKIIPGGAAAQDGRLRVNDSILFVNE---VDVREVTHSAAVEALKEAGSIVRLYV 191
Query: 652 V-SCPPVTTV----LIKRPDLKYQLGFSVQNGI------------ICSLMRGGIAERGG- 693
+ PP V LIK P LGFS+ G+ + ++ GG A + G
Sbjct: 192 MRRKPPAEKVMEIKLIKGPK---GLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGR 248
Query: 694 VRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMK 730
+++G +I+ +N + HE V AL N+ +++K
Sbjct: 249 LQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLK 285
Score = 35.8 bits (81), Expect = 0.15
Identities = 23/56 (41%), Positives = 33/56 (58%), Gaps = 8/56 (14%)
Query: 574 HKGEI-LGVVVV--ESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSL 626
H+G LG +V E G G + ++ ++ GGPA SG+L GDQI+S+NG L
Sbjct: 360 HRGSTGLGFNIVGGEDGEG-----IFISFILAGGPADLSGELRKGDQILSVNGVDL 410
Score = 31.2 bits (69), Expect = 3.7
Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 7/60 (11%)
Query: 671 LGFSVQNG------IICSLMRGGIAERGG-VRVGHRIIEINGQSVVATAHEKIVQALSNS 723
LGF++ G I ++ GG A+ G +R G +I+ +NG + +HE+ AL N+
Sbjct: 366 LGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNA 425
>gi|192447426 post-synaptic density protein 95 isoform 2 [Homo
sapiens]
Length = 721
Score = 53.1 bits (126), Expect = 9e-07
Identities = 42/157 (26%), Positives = 76/157 (48%), Gaps = 25/157 (15%)
Query: 593 PTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQ-TQVKLNI 651
P++ + ++ GG AA+ G+L + D I+ +N V + T ++ LK + V+L +
Sbjct: 89 PSIFITKIIPGGAAAQDGRLRVNDSILFVNE---VDVREVTHSAAVEALKEAGSIVRLYV 145
Query: 652 V-SCPPVTTV----LIKRPDLKYQLGFSVQNGI------------ICSLMRGGIAERGG- 693
+ PP V LIK P LGFS+ G+ + ++ GG A + G
Sbjct: 146 MRRKPPAEKVMEIKLIKGPK---GLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGR 202
Query: 694 VRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMK 730
+++G +I+ +N + HE V AL N+ +++K
Sbjct: 203 LQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLK 239
Score = 35.8 bits (81), Expect = 0.15
Identities = 23/56 (41%), Positives = 33/56 (58%), Gaps = 8/56 (14%)
Query: 574 HKGEI-LGVVVV--ESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSL 626
H+G LG +V E G G + ++ ++ GGPA SG+L GDQI+S+NG L
Sbjct: 314 HRGSTGLGFNIVGGEDGEG-----IFISFILAGGPADLSGELRKGDQILSVNGVDL 364
Score = 31.2 bits (69), Expect = 3.7
Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 7/60 (11%)
Query: 671 LGFSVQNG------IICSLMRGGIAERGG-VRVGHRIIEINGQSVVATAHEKIVQALSNS 723
LGF++ G I ++ GG A+ G +R G +I+ +NG + +HE+ AL N+
Sbjct: 320 LGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNA 379
>gi|223890252 glutamate receptor interacting protein 1 [Homo
sapiens]
Length = 1076
Score = 51.6 bits (122), Expect = 3e-06
Identities = 38/163 (23%), Positives = 73/163 (44%), Gaps = 20/163 (12%)
Query: 595 VILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLN---- 650
V++ + GGPA R G + GD+++S++G L+G A I+K + + +
Sbjct: 180 VVITCVRPGGPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSILKQCGQEAALLIEYDVS 239
Query: 651 -----IVSCPPVTTVLIKRPDLKYQLGFSVQNGIICS--------LMRGGIAER-GGVRV 696
+ P+ + K P LG ++ + C+ + IA+R G + V
Sbjct: 240 VMDSVATASGPLLVEVAKTPGA--SLGVALTTSMCCNKQVIVIDKIKSASIADRCGALHV 297
Query: 697 GHRIIEINGQSVVATAHEKIVQALSNSVGEIHMKTMPAAMFRL 739
G I+ I+G S+ + Q L+N+ ++ ++ +P RL
Sbjct: 298 GDHILSIDGTSMEYCTLAEATQFLANTTDQVKLEILPHHQTRL 340
Score = 47.8 bits (112), Expect = 4e-05
Identities = 42/173 (24%), Positives = 81/173 (46%), Gaps = 24/173 (13%)
Query: 569 LQLEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVG 628
++L K +G LG+ V P V +N+ GG AARS +L +GD I ++NG +L
Sbjct: 54 VELMKKEGTTLGLTVSGGIDKDGKPRV--SNLRQGGIAARSDQLDVGDYIKAVNGINLAK 111
Query: 629 LPLATCQGIIKGLKNQTQVKLNIVSCPPV----TTVLIKRPDLKYQ-----LGFSVQNG- 678
++K + + +++ PPV ++V+ + ++ GF ++ G
Sbjct: 112 FRHDEIISLLKNVGERVVLEVE-YELPPVSVQGSSVIFRTVEVTLHKEGNTFGFVIRGGA 170
Query: 679 ----------IICSLMRGGIAER-GGVRVGHRIIEINGQSVVATAHEKIVQAL 720
+I + GG A+R G ++ G R++ ++G ++ T H + + L
Sbjct: 171 HDDRNKSRPVVITCVRPGGPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSIL 223
Score = 47.4 bits (111), Expect = 5e-05
Identities = 49/203 (24%), Positives = 89/203 (43%), Gaps = 27/203 (13%)
Query: 531 NGINPEDLSQKEYSDIIN--------TQEMYNDDLIHFSNSENCKELQLEKHKGEILGVV 582
NGI ED + +E S ++ T E+ D S ++L K LG+
Sbjct: 476 NGIPTEDSTFEEASQLLRDSSITSKVTLEIEFDVAESVIPSSGTFHVKLPKKHNVELGIT 535
Query: 583 VVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLK 642
+ ++++++ G A R+G L +GD++++I+ L + I++ +
Sbjct: 536 ISSPSSRKPGDPLVISDIKKGSVAHRTGTLELGDKLLAIDNIRLDNCSMEDAVQILQQCE 595
Query: 643 NQTQVKL---------NIVSCPPVTTVLIKRPDLKYQLGFSVQNG-------IICSLMRG 686
+ ++K+ S + TV +KR LG ++ II SL +G
Sbjct: 596 DLVKLKIRKDEDNSDEQESSGAIIYTVELKR--YGGPLGITISGTEEPFDPIIISSLTKG 653
Query: 687 GIAER-GGVRVGHRIIEINGQSV 708
G+AER G + +G RI+ IN S+
Sbjct: 654 GLAERTGAIHIGDRILAINSSSL 676
Score = 43.9 bits (102), Expect = 5e-04
Identities = 31/108 (28%), Positives = 56/108 (51%), Gaps = 5/108 (4%)
Query: 528 LRANGINPEDLSQ--KEYSDIINTQEMYNDDLIHFSNSENCKELQLE-KHKGEILGVVVV 584
+R + + ED Q ++ D++ + ++D S +E K G LG+ +
Sbjct: 577 IRLDNCSMEDAVQILQQCEDLVKLKIRKDEDNSDEQESSGAIIYTVELKRYGGPLGITI- 635
Query: 585 ESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLA 632
SG +I++++ GG A R+G + IGD+I++IN +SL G PL+
Sbjct: 636 -SGTEEPFDPIIISSLTKGGLAERTGAIHIGDRILAINSSSLKGKPLS 682
Score = 35.0 bits (79), Expect = 0.25
Identities = 33/143 (23%), Positives = 60/143 (41%), Gaps = 17/143 (11%)
Query: 605 PAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNI------VSCPPVT 658
PA R G L IGD++M+ING +++ ++V L I P
Sbjct: 459 PAERCGVLQIGDRVMAINGIPTEDSTFEEASQLLRDSSITSKVTLEIEFDVAESVIPSSG 518
Query: 659 TVLIKRPDL-KYQLGFSVQNG---------IICSLMRGGIAER-GGVRVGHRIIEINGQS 707
T +K P +LG ++ + +I + +G +A R G + +G +++ I+
Sbjct: 519 TFHVKLPKKHNVELGITISSPSSRKPGDPLVISDIKKGSVAHRTGTLELGDKLLAIDNIR 578
Query: 708 VVATAHEKIVQALSNSVGEIHMK 730
+ + E VQ L + +K
Sbjct: 579 LDNCSMEDAVQILQQCEDLVKLK 601
Score = 32.0 bits (71), Expect = 2.2
Identities = 23/64 (35%), Positives = 34/64 (53%), Gaps = 9/64 (14%)
Query: 671 LGFSVQNGI-------ICSLMRGGIAERGG-VRVGHRIIEINGQSVVATAHEKIVQALSN 722
LG +V GI + +L +GGIA R + VG I +NG ++ H++I+ L N
Sbjct: 64 LGLTVSGGIDKDGKPRVSNLRQGGIAARSDQLDVGDYIKAVNGINLAKFRHDEIISLLKN 123
Query: 723 SVGE 726
VGE
Sbjct: 124 -VGE 126
>gi|119943106 synapse-associated protein 102 isoform a [Homo
sapiens]
Length = 817
Score = 51.6 bits (122), Expect = 3e-06
Identities = 33/151 (21%), Positives = 70/151 (46%), Gaps = 13/151 (8%)
Query: 593 PTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIV 652
P + + ++ GG AA G+L + D ++ +N + + + +K ++ +
Sbjct: 158 PGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVSEVVHSRAVEALKEAGPVVRLVVRRR 217
Query: 653 SCPPVTTVLIKRPDLKYQLGFSVQNGI------------ICSLMRGGIAERGG-VRVGHR 699
PP T + + LGFS+ GI I ++ GG A++ G +++G R
Sbjct: 218 QPPPETIMEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDR 277
Query: 700 IIEINGQSVVATAHEKIVQALSNSVGEIHMK 730
++ +N ++ HE+ V +L N+ +++K
Sbjct: 278 LLAVNNTNLQDVRHEEAVASLKNTSDMVYLK 308
Score = 35.4 bits (80), Expect = 0.20
Identities = 23/56 (41%), Positives = 34/56 (60%), Gaps = 8/56 (14%)
Query: 574 HKGEI-LGVVVV--ESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSL 626
HKG LG +V E G G + ++ ++ GGPA SG+L GD+I+S+NG +L
Sbjct: 390 HKGSTGLGFNIVGGEDGEG-----IFVSFILAGGPADLSGELRRGDRILSVNGVNL 440
Score = 30.4 bits (67), Expect = 6.3
Identities = 18/60 (30%), Positives = 31/60 (51%), Gaps = 7/60 (11%)
Query: 671 LGFSVQNG------IICSLMRGGIAERGG-VRVGHRIIEINGQSVVATAHEKIVQALSNS 723
LGF++ G + ++ GG A+ G +R G RI+ +NG ++ HE+ AL +
Sbjct: 396 LGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRA 455
>gi|222446609 rai-like protein [Homo sapiens]
Length = 630
Score = 50.8 bits (120), Expect = 4e-06
Identities = 55/270 (20%), Positives = 111/270 (41%), Gaps = 52/270 (19%)
Query: 307 PEERLKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGPCEP--- 363
P +L+ + +G P P ++ + A P +PGP EP
Sbjct: 115 PRLKLQESRDPGSSGPSSPETSLSRSGTAPPPQQDLVGHRATALTPDSCPLPGPGEPTLR 174
Query: 364 --------EDLID-GIIFAANYLGSTQLL-SERNPSKNIRMMQAQEAVSR---------- 403
+ L+ G+ + Y+G ++L S R+ +R +EA+SR
Sbjct: 175 SRQDRHFLQHLLGMGMNYCVRYMGCVEVLQSMRSLDFGMRTQVTREAISRLCEAVPGANG 234
Query: 404 -VKRMQKAAKIKKKANSEGDAQ-TLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIA 461
+K+ + K + + Q + + L IST + ++N D Q+ + +H +++IS+ +
Sbjct: 235 AIKKRKPPVKFLSTVLGKSNLQFSGMNIKLTISTCSLTLMNLDNQQIIANHHMQSISFAS 294
Query: 462 ----DIGNIVVLMARRRMPRSASQDCIETTPGAQEGKKQYKMICHVFESED--AQLIAQS 515
D + V +A+ + + A CH+ E + AQ + +
Sbjct: 295 GGDPDTTDYVAYVAKDPVNQRA---------------------CHILECHNGMAQDVIST 333
Query: 516 IGQAFSVAYQEFLRANGINPEDLSQKEYSD 545
IGQAF + ++++L+ +N S++ + D
Sbjct: 334 IGQAFELRFKQYLKNPSLNTSCESEEVHID 363
>gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]
Length = 904
Score = 50.4 bits (119), Expect = 6e-06
Identities = 38/161 (23%), Positives = 80/161 (49%), Gaps = 20/161 (12%)
Query: 594 TVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQ-TQVKLNIV 652
++ + ++ GG AA+ G+L + D I+ +N V + T ++ LK + V+L +
Sbjct: 252 SIFITKIITGGAAAQDGRLRVNDCILRVNE---VDVRDVTHSKAVEALKEAGSIVRLYVK 308
Query: 653 SCPPVTTVLIKRPDLK--YQLGFSVQNGI------------ICSLMRGGIAERGG-VRVG 697
PV+ +++ +K LGFS+ G+ + ++ GG A + G +++G
Sbjct: 309 RRKPVSEKIMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIG 368
Query: 698 HRIIEINGQSVVATAHEKIVQALSNSVGEIHMK-TMPAAMF 737
+++ +N + HE+ V AL N+ +++K P +M+
Sbjct: 369 DKLLAVNNVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMY 409
Score = 38.1 bits (87), Expect = 0.030
Identities = 44/192 (22%), Positives = 72/192 (37%), Gaps = 65/192 (33%)
Query: 594 TVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQ--------- 644
++ + ++ GG A + GKL IGD+++++N V L T + + LKN
Sbjct: 347 SIYVTKIIEGGAAHKDGKLQIGDKLLAVNN---VCLEEVTHEEAVTALKNTSDFVYLKVA 403
Query: 645 --TQVKLNIVSCPPVTTVLIKRP-----------------DLKYQ--------------- 670
T + +N PP T +P +Y
Sbjct: 404 KPTSMYMNDGYAPPDITNSSSQPVDNHVSPSSFLGQTPASPARYSPVSKAVLGDDEITRE 463
Query: 671 ------------LGFSVQNG------IICSLMRGGIAERGG-VRVGHRIIEINGQSVVAT 711
LGF++ G I ++ GG A+ G +R G RII +N + A
Sbjct: 464 PRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAA 523
Query: 712 AHEKIVQALSNS 723
+HE+ AL N+
Sbjct: 524 SHEQAAAALKNA 535
Score = 32.3 bits (72), Expect = 1.7
Identities = 27/76 (35%), Positives = 40/76 (52%), Gaps = 11/76 (14%)
Query: 574 HKGEI-LGVVVV--ESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLP 630
H+G LG +V E G G + ++ ++ GGPA SG+L GD+I+S+N V L
Sbjct: 470 HRGSTGLGFNIVGGEDGEG-----IFISFILAGGPADLSGELRKGDRIISVNS---VDLR 521
Query: 631 LATCQGIIKGLKNQTQ 646
A+ + LKN Q
Sbjct: 522 AASHEQAAAALKNAGQ 537
>gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]
Length = 926
Score = 50.4 bits (119), Expect = 6e-06
Identities = 38/161 (23%), Positives = 80/161 (49%), Gaps = 20/161 (12%)
Query: 594 TVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQ-TQVKLNIV 652
++ + ++ GG AA+ G+L + D I+ +N V + T ++ LK + V+L +
Sbjct: 252 SIFITKIITGGAAAQDGRLRVNDCILRVNE---VDVRDVTHSKAVEALKEAGSIVRLYVK 308
Query: 653 SCPPVTTVLIKRPDLK--YQLGFSVQNGI------------ICSLMRGGIAERGG-VRVG 697
PV+ +++ +K LGFS+ G+ + ++ GG A + G +++G
Sbjct: 309 RRKPVSEKIMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIG 368
Query: 698 HRIIEINGQSVVATAHEKIVQALSNSVGEIHMK-TMPAAMF 737
+++ +N + HE+ V AL N+ +++K P +M+
Sbjct: 369 DKLLAVNNVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMY 409
Score = 38.1 bits (87), Expect = 0.030
Identities = 44/192 (22%), Positives = 72/192 (37%), Gaps = 65/192 (33%)
Query: 594 TVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQ--------- 644
++ + ++ GG A + GKL IGD+++++N V L T + + LKN
Sbjct: 347 SIYVTKIIEGGAAHKDGKLQIGDKLLAVNN---VCLEEVTHEEAVTALKNTSDFVYLKVA 403
Query: 645 --TQVKLNIVSCPPVTTVLIKRP-----------------DLKYQ--------------- 670
T + +N PP T +P +Y
Sbjct: 404 KPTSMYMNDGYAPPDITNSSSQPVDNHVSPSSFLGQTPASPARYSPVSKAVLGDDEITRE 463
Query: 671 ------------LGFSVQNG------IICSLMRGGIAERGG-VRVGHRIIEINGQSVVAT 711
LGF++ G I ++ GG A+ G +R G RII +N + A
Sbjct: 464 PRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAA 523
Query: 712 AHEKIVQALSNS 723
+HE+ AL N+
Sbjct: 524 SHEQAAAALKNA 535
Score = 32.3 bits (72), Expect = 1.7
Identities = 27/76 (35%), Positives = 40/76 (52%), Gaps = 11/76 (14%)
Query: 574 HKGEI-LGVVVV--ESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLP 630
H+G LG +V E G G + ++ ++ GGPA SG+L GD+I+S+N V L
Sbjct: 470 HRGSTGLGFNIVGGEDGEG-----IFISFILAGGPADLSGELRKGDRIISVNS---VDLR 521
Query: 631 LATCQGIIKGLKNQTQ 646
A+ + LKN Q
Sbjct: 522 AASHEQAAAALKNAGQ 537
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 50.4 bits (119), Expect = 6e-06
Identities = 67/286 (23%), Positives = 101/286 (35%), Gaps = 41/286 (14%)
Query: 28 EPESEDMELPLEGYVPEGLELAALRPESPAPEEQECHNHSPDGDSSSDYVNNTSEEEDYD 87
+PESED+E P + ++PES E E + S + + E+E
Sbjct: 1884 QPESEDVETPEAEW--------EVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPES 1935
Query: 88 EG--------LPEEEEGITYYIRYCPEDDSYLEGMDCNGEEYLAHSAHPVDTDECQ-EAV 138
EG +E EG T E E E+ A V+T E + EA
Sbjct: 1936 EGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVE-VETQEAEGEAQ 1994
Query: 139 EEWTDSAGPHPHG------HEAEGSQDYPDGQLPIPEDEPSVLEAHDQEEDGHYCASKEG 192
E D P G EA+ D + Q +E +E Q+ +G +G
Sbjct: 1995 PESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDG 2054
Query: 193 YQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMTSITSASEASPEH 252
+ EA + ++ +G+ + ED+D AE EA PE
Sbjct: 2055 VE---APEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAE-------------GEAQPES 2098
Query: 253 GPEPGPEDSVEACPPIKASCSPSRHEARPKSLNL-LPEAKHPGDPQ 297
PE EA + EA+P+S + PEA+ P+
Sbjct: 2099 EGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPE 2144
Score = 34.7 bits (78), Expect = 0.33
Identities = 65/322 (20%), Positives = 118/322 (36%), Gaps = 64/322 (19%)
Query: 10 GSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEEQECHNHSPD 69
GSG D+ Q+P D +E EG +PES E E +
Sbjct: 1807 GSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEG----EAQPESEGVEAPEA-----E 1857
Query: 70 GDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEEYLAHSAHPV 129
GD+ +E E PE E+ +E + GE + V
Sbjct: 1858 GDA----------QEAEGEAQPESED---------------VEAPEAEGEAQ--PESEDV 1890
Query: 130 DTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQEEDGHYCAS 189
+T E + V+ ++ A EA+ + + EDEP A QE + A+
Sbjct: 1891 ETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEE---AA 1947
Query: 190 KEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMTSITSASEAS 249
+E PE + + + + + + ED++ + E++ EA
Sbjct: 1948 QEAEGQTQPE-------SEVIESQEAEEEAQPESEDVEALEVEVE----------TQEAE 1990
Query: 250 PEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGFKPKTRTPEE 309
E PE + VEA P + + EA+P+S + + K G+ + + +T +
Sbjct: 1991 GEAQPE---SEDVEA-PEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGET----Q 2042
Query: 310 RLKWPHEQVCNGLEQPRKQQRS 331
+ + + +G+E P ++ +
Sbjct: 2043 KTEGDAQPESDGVEAPEAEEEA 2064
>gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]
Length = 749
Score = 50.1 bits (118), Expect = 8e-06
Identities = 40/154 (25%), Positives = 73/154 (47%), Gaps = 19/154 (12%)
Query: 593 PTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQ-VKLNI 651
P + + ++ GG AA G+L + D I+ +N V + + ++ LK V+L +
Sbjct: 74 PGIFITKIIPGGAAAEDGRLRVNDCILRVNE---VDVSEVSHSKAVEALKEAGSIVRLYV 130
Query: 652 VSCPPV--TTVLIKRPDLKYQLGFSVQNGI------------ICSLMRGGIAERGG-VRV 696
P+ T V IK LGFS+ G+ + ++ GG A++ G ++V
Sbjct: 131 RRRRPILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQV 190
Query: 697 GHRIIEINGQSVVATAHEKIVQALSNSVGEIHMK 730
G R++ +N S+ HE+ V L N+ +++K
Sbjct: 191 GDRLLMVNNYSLEEVTHEEAVAILKNTSEVVYLK 224
Score = 39.3 bits (90), Expect = 0.014
Identities = 27/70 (38%), Positives = 37/70 (52%), Gaps = 8/70 (11%)
Query: 574 HKGEI-LGVVVV--ESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLP 630
HKG LG +V E G G + ++ ++ GGPA SG+L GDQI+S+NG L G
Sbjct: 322 HKGSTGLGFNIVGGEDGEG-----IFVSFILAGGPADLSGELQRGDQILSVNGIDLRGAS 376
Query: 631 LATCQGIIKG 640
+KG
Sbjct: 377 HEQAAAALKG 386
Score = 33.5 bits (75), Expect = 0.74
Identities = 20/72 (27%), Positives = 40/72 (55%), Gaps = 5/72 (6%)
Query: 594 TVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVS 653
++ + +++GG A + G+L +GD+++ +N SL + T + + LKN ++V V
Sbjct: 170 SIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEV---THEEAVAILKNTSEVVYLKVG 226
Query: 654 CPPVTTVLIKRP 665
P TT+ + P
Sbjct: 227 KP--TTIYMTDP 236
>gi|218156338 chapsyn-110 isoform 1 [Homo sapiens]
Length = 975
Score = 50.1 bits (118), Expect = 8e-06
Identities = 40/154 (25%), Positives = 73/154 (47%), Gaps = 19/154 (12%)
Query: 593 PTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQ-VKLNI 651
P + + ++ GG AA G+L + D I+ +N V + + ++ LK V+L +
Sbjct: 230 PGIFITKIIPGGAAAEDGRLRVNDCILRVNE---VDVSEVSHSKAVEALKEAGSIVRLYV 286
Query: 652 VSCPPV--TTVLIKRPDLKYQLGFSVQNGI------------ICSLMRGGIAERGG-VRV 696
P+ T V IK LGFS+ G+ + ++ GG A++ G ++V
Sbjct: 287 RRRRPILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQV 346
Query: 697 GHRIIEINGQSVVATAHEKIVQALSNSVGEIHMK 730
G R++ +N S+ HE+ V L N+ +++K
Sbjct: 347 GDRLLMVNNYSLEEVTHEEAVAILKNTSEVVYLK 380
Score = 39.3 bits (90), Expect = 0.014
Identities = 27/70 (38%), Positives = 37/70 (52%), Gaps = 8/70 (11%)
Query: 574 HKGEI-LGVVVV--ESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLP 630
HKG LG +V E G G + ++ ++ GGPA SG+L GDQI+S+NG L G
Sbjct: 530 HKGSTGLGFNIVGGEDGEG-----IFVSFILAGGPADLSGELQRGDQILSVNGIDLRGAS 584
Query: 631 LATCQGIIKG 640
+KG
Sbjct: 585 HEQAAAALKG 594
Score = 33.5 bits (75), Expect = 0.74
Identities = 20/72 (27%), Positives = 40/72 (55%), Gaps = 5/72 (6%)
Query: 594 TVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVS 653
++ + +++GG A + G+L +GD+++ +N SL + T + + LKN ++V V
Sbjct: 326 SIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEV---THEEAVAILKNTSEVVYLKVG 382
Query: 654 CPPVTTVLIKRP 665
P TT+ + P
Sbjct: 383 KP--TTIYMTDP 392
>gi|91199538 chapsyn-110 isoform 2 [Homo sapiens]
Length = 870
Score = 50.1 bits (118), Expect = 8e-06
Identities = 40/154 (25%), Positives = 73/154 (47%), Gaps = 19/154 (12%)
Query: 593 PTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQ-VKLNI 651
P + + ++ GG AA G+L + D I+ +N V + + ++ LK V+L +
Sbjct: 125 PGIFITKIIPGGAAAEDGRLRVNDCILRVNE---VDVSEVSHSKAVEALKEAGSIVRLYV 181
Query: 652 VSCPPV--TTVLIKRPDLKYQLGFSVQNGI------------ICSLMRGGIAERGG-VRV 696
P+ T V IK LGFS+ G+ + ++ GG A++ G ++V
Sbjct: 182 RRRRPILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQV 241
Query: 697 GHRIIEINGQSVVATAHEKIVQALSNSVGEIHMK 730
G R++ +N S+ HE+ V L N+ +++K
Sbjct: 242 GDRLLMVNNYSLEEVTHEEAVAILKNTSEVVYLK 275
Score = 39.3 bits (90), Expect = 0.014
Identities = 27/70 (38%), Positives = 37/70 (52%), Gaps = 8/70 (11%)
Query: 574 HKGEI-LGVVVV--ESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLP 630
HKG LG +V E G G + ++ ++ GGPA SG+L GDQI+S+NG L G
Sbjct: 425 HKGSTGLGFNIVGGEDGEG-----IFVSFILAGGPADLSGELQRGDQILSVNGIDLRGAS 479
Query: 631 LATCQGIIKG 640
+KG
Sbjct: 480 HEQAAAALKG 489
Score = 33.5 bits (75), Expect = 0.74
Identities = 20/72 (27%), Positives = 40/72 (55%), Gaps = 5/72 (6%)
Query: 594 TVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVS 653
++ + +++GG A + G+L +GD+++ +N SL + T + + LKN ++V V
Sbjct: 221 SIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEV---THEEAVAILKNTSEVVYLKVG 277
Query: 654 CPPVTTVLIKRP 665
P TT+ + P
Sbjct: 278 KP--TTIYMTDP 287
>gi|38570142 membrane protein, palmitoylated 5 [Homo sapiens]
Length = 675
Score = 48.1 bits (113), Expect = 3e-05
Identities = 74/341 (21%), Positives = 130/341 (38%), Gaps = 74/341 (21%)
Query: 293 PGDPQRGFKPKTRTPE-ERLKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASF 351
PGD P R+ + ER++ E + E+ K+Q DLN + KK+A
Sbjct: 40 PGDLGTRMMPIRRSAQLERIRQQQEDMRRRREEEGKKQELDLNSSM------RLKKLAQI 93
Query: 352 PSFVAVPGPCEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAA 411
P + P D +GI+ +P +++++ ++ S +K +Q
Sbjct: 94 PPKTGIDNPMF--DTEEGIVL-------------ESPHYAVKILEIEDLFSSLKHIQHTL 138
Query: 412 KIKKKANSEGDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMA 471
D+Q+ ++ L + V N D Q H N + +
Sbjct: 139 V---------DSQSQEDISLLLQL----VQNKDFQNAFKIH------------NAITVHM 173
Query: 472 RRRMPR----SASQDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEF 527
+ P S +QD AQE + K + H E L+ QA +A+ +
Sbjct: 174 NKASPPFPLISNAQDL------AQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKV 227
Query: 528 LRANGINPEDLSQKEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESG 587
Q+ + I + +Y I E K +++EK + LG V
Sbjct: 228 AE----------QEMQLEPITDERVYES--IGQYGGETVKIVRIEKARDIPLGATVRNE- 274
Query: 588 WGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVG 628
+ +VI++ ++ GG A +SG L GD+++ ING + G
Sbjct: 275 ----MDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311
>gi|169212742 PREDICTED: similar to hCG1654128 [Homo sapiens]
Length = 1015
Score = 47.4 bits (111), Expect = 5e-05
Identities = 61/219 (27%), Positives = 86/219 (39%), Gaps = 39/219 (17%)
Query: 53 PESPAPEEQECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLE 112
PE +P E + + +S + ++ED E E G+ PED E
Sbjct: 236 PEDASPTEHDVGQEEDGPEDASPTEHGVDQQEDGPEDASPTEHGVDQQ-EDGPEDARPTE 294
Query: 113 -GMDC--NGEEYLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPE 169
G+D +G E + + H VD E + + A P HG + E DG PE
Sbjct: 295 HGVDQEEDGPEDASLTEHGVDQQE------DGPEDASPTEHGIDQE-----EDG----PE 339
Query: 170 DEPSVLEAHDQEEDGHYCASKEGYQDYYPEEANGNTGASP--YRLRRGDG--DLEDQEED 225
D DQEEDG AS ++ +E +G ASP + + + DG D E
Sbjct: 340 DASPTEHGVDQEEDGPEDASPTEHEHGVDQEEDGPEDASPTEHGVDQEDGPEDARPTEHG 399
Query: 226 IDQIVAEIKMSLSMTSITSASEASP-EHG--PEPGPEDS 261
+DQ +A P EHG E GPED+
Sbjct: 400 VDQ-------------EDGPEDARPTEHGVDQEDGPEDA 425
>gi|10835173 nitric oxide synthase 1, neuronal [Homo sapiens]
Length = 1434
Score = 46.2 bits (108), Expect = 1e-04
Identities = 28/85 (32%), Positives = 48/85 (56%), Gaps = 3/85 (3%)
Query: 565 NCKELQLEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGT 624
N ++L K K LG +V E P VI+++++ GG A +SG + GD I+++NG
Sbjct: 14 NVISVRLFKRKVGGLGFLVKER---VSKPPVIISDLIRGGAAEQSGLIQAGDIILAVNGR 70
Query: 625 SLVGLPLATCQGIIKGLKNQTQVKL 649
LV L + +++G+ ++T V L
Sbjct: 71 PLVDLSYDSALEVLRGIASETHVVL 95
Score = 35.8 bits (81), Expect = 0.15
Identities = 17/52 (32%), Positives = 31/52 (59%), Gaps = 1/52 (1%)
Query: 679 IICSLMRGGIAERGG-VRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHM 729
II L+RGG AE+ G ++ G I+ +NG+ +V +++ ++ L E H+
Sbjct: 42 IISDLIRGGAAEQSGLIQAGDIILAVNGRPLVDLSYDSALEVLRGIASETHV 93
>gi|169213065 PREDICTED: similar to hCG1654128 [Homo sapiens]
Length = 851
Score = 45.8 bits (107), Expect = 1e-04
Identities = 67/234 (28%), Positives = 93/234 (39%), Gaps = 29/234 (12%)
Query: 42 VPEGLELAALRPESPAPEEQECHNHSPDGD-SSSDYVNNTSEEEDYDEGLPEEEEGITYY 100
VP GL E + + GD +S ++ +EED E E G+
Sbjct: 27 VPGGLTAGTRIIHLRETERRSSQRRAELGDCDASPTEHDVGQEEDGPEDASPTEHGVDQQ 86
Query: 101 IRYCPEDDSYLE-GMDC-NGEEYLAHSAHPVDTDECQEAVEEWTDSAGPHPHG--HEAEG 156
PED S E G++ +G E + + H VD E + + A P HG E +G
Sbjct: 87 -EDGPEDASPTEHGVNQEDGPEDASPTEHGVDQQE------DGPEDARPTEHGIDQEEDG 139
Query: 157 SQDYP------DGQLPIPEDEPSVLEAHDQEEDGHYCASKEGYQDYYPEEANGNTGASPY 210
+D D Q PED DQEEDG AS ++ +E +G ASP
Sbjct: 140 PEDASLTEHGVDQQEDGPEDASPTEHGIDQEEDGPEDASPTEHEHGVDQEEDGPEDASP- 198
Query: 211 RLRRGDGDLEDQEEDIDQIVAEIKMSLSMTSITSASEASP-EHG--PEPGPEDS 261
G DQEED + + + + +A P EHG E GPED+
Sbjct: 199 -TEHG----VDQEEDGPEDASPTEHGVDQED--GPEDARPTEHGVDQEDGPEDA 245
>gi|122937249 glutamate receptor interacting protein 2 [Homo
sapiens]
Length = 1141
Score = 45.8 bits (107), Expect = 1e-04
Identities = 43/173 (24%), Positives = 77/173 (44%), Gaps = 23/173 (13%)
Query: 569 LQLEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVG 628
++L K +G LG+ + P V +N+ GG AARS L+IGD I S+NG L
Sbjct: 146 VELIKKEGSTLGLTISGGTDKDGKPRV--SNLRPGGLAARSDLLNIGDYIRSVNGIHLTR 203
Query: 629 LPLATCQGIIKGLKNQTQVKLNIVSCPPV----TTVLIKRPDLKY-----QLGFSVQNG- 678
L ++K + + +++ PP ++ K D+ GF ++ G
Sbjct: 204 LRHDEIITLLKNVGERVVLEVEYELPPPAPENNPRIISKTVDVSLYKEGNSFGFVLRGGA 263
Query: 679 ----------IICSLMRGGIAER-GGVRVGHRIIEINGQSVVATAHEKIVQAL 720
++ + GG A+R G ++VG R++ ++G + +H + L
Sbjct: 264 HEDGHKSRPLVLTYVRPGGPADREGSLKVGDRLLSVDGIPLHGASHATALATL 316
Score = 43.5 bits (101), Expect = 7e-04
Identities = 33/155 (21%), Positives = 75/155 (48%), Gaps = 16/155 (10%)
Query: 595 VILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQT--QVKLNIV 652
++L + GGPA R G L +GD+++S++G L G AT ++ ++ QV+ ++
Sbjct: 273 LVLTYVRPGGPADREGSLKVGDRLLSVDGIPLHGASHATALATLRQCSHEALFQVEYDVA 332
Query: 653 -------SCPPVTTVLIKRPDLKYQLGF---SVQNGIICSLMR---GGIAER-GGVRVGH 698
+ P+ ++K P + S++N + ++ R + +R G + G
Sbjct: 333 TPDTVANASGPLMVEIVKTPGSALGISLTTTSLRNKSVITIDRIKPASVVDRSGALHPGD 392
Query: 699 RIIEINGQSVVATAHEKIVQALSNSVGEIHMKTMP 733
I+ I+G S+ + + + L++ ++ ++ +P
Sbjct: 393 HILSIDGTSMEHCSLLEATKLLASISEKVRLEILP 427
Score = 42.4 bits (98), Expect = 0.002
Identities = 47/206 (22%), Positives = 93/206 (45%), Gaps = 28/206 (13%)
Query: 528 LRANGINPEDLSQKEYSDIINTQEMYNDDLIHFS--------NSENCKELQLEKHKGEIL 579
L NGI ED + +E + ++ + + ++ S ++L K + L
Sbjct: 607 LSINGIATEDGTMEEANQLLRDAALAHKVVLEVEFDVAESVIPSSGTFHVKLPKKRSVEL 666
Query: 580 GVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIK 639
G+ + + P +I++++ G A R+G L GD++++I+ L P+ I++
Sbjct: 667 GITISSASRKRGEP-LIISDIKKGSVAHRTGTLEPGDKLLAIDNIRLDNCPMEDAVQILR 725
Query: 640 GLKNQTQVKL--------NIVSCPPVT-TVLIKRPDLKYQLGFSVQNG-------IICSL 683
++ ++K+ + + V+ TV +KR LG ++ +I L
Sbjct: 726 QCEDLVKLKIRKDEDNSDELETTGAVSYTVELKR--YGGPLGITISGTEEPFDPIVISGL 783
Query: 684 MRGGIAER-GGVRVGHRIIEINGQSV 708
+ G+AER G + VG RI+ IN S+
Sbjct: 784 TKRGLAERTGAIHVGDRILAINNVSL 809
Score = 38.9 bits (89), Expect = 0.018
Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 2/60 (3%)
Query: 573 KHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLA 632
K G LG+ + SG ++++ + G A R+G + +GD+I++IN SL G PL+
Sbjct: 758 KRYGGPLGITI--SGTEEPFDPIVISGLTKRGLAERTGAIHVGDRILAINNVSLKGRPLS 815
Score = 33.5 bits (75), Expect = 0.74
Identities = 32/142 (22%), Positives = 60/142 (42%), Gaps = 16/142 (11%)
Query: 605 PAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNI------VSCPPVT 658
PA R G L +GD+++SING + + +++ +V L + P
Sbjct: 593 PAERCGLLQVGDRVLSINGIATEDGTMEEANQLLRDAALAHKVVLEVEFDVAESVIPSSG 652
Query: 659 TVLIKRPDLK-YQLGFSVQNG--------IICSLMRGGIAER-GGVRVGHRIIEINGQSV 708
T +K P + +LG ++ + II + +G +A R G + G +++ I+ +
Sbjct: 653 TFHVKLPKKRSVELGITISSASRKRGEPLIISDIKKGSVAHRTGTLEPGDKLLAIDNIRL 712
Query: 709 VATAHEKIVQALSNSVGEIHMK 730
E VQ L + +K
Sbjct: 713 DNCPMEDAVQILRQCEDLVKLK 734
>gi|45827729 scribble isoform b [Homo sapiens]
Length = 1630
Score = 45.8 bits (107), Expect = 1e-04
Identities = 46/155 (29%), Positives = 75/155 (48%), Gaps = 27/155 (17%)
Query: 593 PTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIV 652
P V ++ ++ G AARSG L +GD+I+++NG + AT Q + L ++L+++
Sbjct: 1034 PGVFISKVLPRGLAARSG-LRVGDRILAVNGQDVRD---ATHQEAVSALLRPC-LELSLL 1088
Query: 653 ----SCPPVTTVLIKRPDLKYQLGFSVQNG----------------IICSLMRGGIAERG 692
PP L + +LG S++ G I + G A R
Sbjct: 1089 VRRDPAPPGLRELCIQKAPGERLGISIRGGARGHAGNPRDPTDEGIFISKVSPTGAAGRD 1148
Query: 693 G-VRVGHRIIEINGQSVVATAHEKIVQALSNSVGE 726
G +RVG R++E+N QS++ H + VQ L SVG+
Sbjct: 1149 GRLRVGLRLLEVNQQSLLGLTHGEAVQLL-RSVGD 1182
Score = 44.3 bits (103), Expect = 4e-04
Identities = 44/187 (23%), Positives = 66/187 (35%), Gaps = 61/187 (32%)
Query: 595 VILANMMNGGPAARSGKLSIGDQIMSINGTSL--------------------------VG 628
+ ++ + GG A R+G L +GD+++SING + G
Sbjct: 892 IFVSRIAEGGAAHRAGTLQVGDRVLSINGVDVTEARHDHAVSLLTAASPTIALLLEREAG 951
Query: 629 LPL--------------------ATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKRPDLK 668
PL T + GL + L P I+ P
Sbjct: 952 GPLPPSPLPHSSPPTAAVATTSITTATPGVPGLPSLAPSLLAAALEGPYPVEEIRLPRAG 1011
Query: 669 YQLGFSVQNG---------------IICSLMRGGIAERGGVRVGHRIIEINGQSVVATAH 713
LG S+ G I ++ G+A R G+RVG RI+ +NGQ V H
Sbjct: 1012 GPLGLSIVGGSDHSSHPFGVQEPGVFISKVLPRGLAARSGLRVGDRILAVNGQDVRDATH 1071
Query: 714 EKIVQAL 720
++ V AL
Sbjct: 1072 QEAVSAL 1078
Score = 43.1 bits (100), Expect = 0.001
Identities = 39/180 (21%), Positives = 68/180 (37%), Gaps = 54/180 (30%)
Query: 595 VILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKL---NI 651
+ ++ + GPAAR+G + +GD+++ +NG +L G ++G Q+++ +
Sbjct: 758 IFISRVSEEGPAARAG-VRVGDKLLEVNGVALQGAEHHEAVEALRGAGTAVQMRVWRERM 816
Query: 652 VSCPPVTTVLIKRPDLKYQ------------------------------------LGFSV 675
V T+ RP+ Y LGFS+
Sbjct: 817 VEPENAVTITPLRPEDDYSPRERRGGGLRLPLLPPESPGPLRQRHVACLARSERGLGFSI 876
Query: 676 QNG-------------IICSLMRGGIAERGG-VRVGHRIIEINGQSVVATAHEKIVQALS 721
G + + GG A R G ++VG R++ ING V H+ V L+
Sbjct: 877 AGGKGSTPYRAGDAGIFVSRIAEGGAAHRAGTLQVGDRVLSINGVDVTEARHDHAVSLLT 936
Score = 37.0 bits (84), Expect = 0.067
Identities = 16/44 (36%), Positives = 27/44 (61%)
Query: 687 GIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMK 730
G A R GVRVG +++E+NG ++ H + V+AL + + M+
Sbjct: 767 GPAARAGVRVGDKLLEVNGVALQGAEHHEAVEALRGAGTAVQMR 810
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.131 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,843,310
Number of Sequences: 37866
Number of extensions: 1786738
Number of successful extensions: 6905
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 133
Number of HSP's successfully gapped in prelim test: 211
Number of HSP's that attempted gapping in prelim test: 6039
Number of HSP's gapped (non-prelim): 957
length of query: 749
length of database: 18,247,518
effective HSP length: 110
effective length of query: 639
effective length of database: 14,082,258
effective search space: 8998562862
effective search space used: 8998562862
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.