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Search of human proteins with 11496885
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]
(457 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens] 969 0.0
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens] 872 0.0
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens] 426 e-119
gi|47157328 PDZ and LIM domain 7 isoform 4 [Homo sapiens] 390 e-108
gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens] 325 7e-89
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens] 322 3e-88
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 300 1e-81
gi|58533161 PDZ and LIM domain 5 isoform e [Homo sapiens] 170 2e-42
gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens] 170 2e-42
gi|109638745 transforming growth factor beta 1 induced transcrip... 167 2e-41
gi|21361591 transforming growth factor beta 1 induced transcript... 167 2e-41
gi|122056619 LIM domain binding 3 isoform 4 [Homo sapiens] 141 1e-33
gi|221316659 leupaxin isoform 1 [Homo sapiens] 135 1e-31
gi|4758670 leupaxin isoform 2 [Homo sapiens] 135 1e-31
gi|170932518 paxillin isoform 3 [Homo sapiens] 131 1e-30
gi|170932516 paxillin isoform 2 [Homo sapiens] 131 1e-30
gi|170932514 paxillin isoform 1 [Homo sapiens] 131 1e-30
gi|238859658 LIM and senescent cell antigen-like domains 2 isofo... 131 1e-30
gi|238776788 LIM and senescent cell antigen-like domains 2 isofo... 131 1e-30
gi|238776786 LIM and senescent cell antigen-like domains 2 isofo... 131 1e-30
gi|40804748 LIM and senescent cell antigen-like domains 2 isofor... 131 1e-30
gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo ... 127 2e-29
gi|13994151 PDZ and LIM domain 1 [Homo sapiens] 124 2e-28
gi|19923181 PDZ and LIM domain 4 isoform 1 [Homo sapiens] 120 3e-27
gi|166235178 PDZ and LIM domain protein 3 isoform b [Homo sapiens] 120 3e-27
gi|54112385 four and a half LIM domains 3 [Homo sapiens] 115 6e-26
gi|122056617 LIM domain binding 3 isoform 3 [Homo sapiens] 114 2e-25
gi|7662330 actin binding LIM protein family, member 3 [Homo sapi... 111 1e-24
gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens] 109 6e-24
gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens] 109 6e-24
>gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]
Length = 457
Score = 969 bits (2506), Expect = 0.0
Identities = 457/457 (100%), Positives = 457/457 (100%)
Query: 1 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS 60
MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS
Sbjct: 1 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS 60
Query: 61 LTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFG 120
LTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFG
Sbjct: 61 LTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFG 120
Query: 121 APPPADSAPQQNGQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQ 180
APPPADSAPQQNGQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQ
Sbjct: 121 APPPADSAPQQNGQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQ 180
Query: 181 DPDEEHLKKSSQVPRTEAPAPASSTPQEPWPGPTAPSPTSRPPWAVDPAFAERYAPDKTS 240
DPDEEHLKKSSQVPRTEAPAPASSTPQEPWPGPTAPSPTSRPPWAVDPAFAERYAPDKTS
Sbjct: 181 DPDEEHLKKSSQVPRTEAPAPASSTPQEPWPGPTAPSPTSRPPWAVDPAFAERYAPDKTS 240
Query: 241 TVLTRHSQPATPTPLQSRTSIVQAAAGGVPGGGSNNGKTPVCHQCHKVIRGRYLVALGHA 300
TVLTRHSQPATPTPLQSRTSIVQAAAGGVPGGGSNNGKTPVCHQCHKVIRGRYLVALGHA
Sbjct: 241 TVLTRHSQPATPTPLQSRTSIVQAAAGGVPGGGSNNGKTPVCHQCHKVIRGRYLVALGHA 300
Query: 301 YHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEIMHALKMTW 360
YHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEIMHALKMTW
Sbjct: 301 YHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEIMHALKMTW 360
Query: 361 HVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFS 420
HVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFS
Sbjct: 361 HVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFS 420
Query: 421 WHDTCFVCAICQINLEGKTFYSKKDRPLCKSHAFSHV 457
WHDTCFVCAICQINLEGKTFYSKKDRPLCKSHAFSHV
Sbjct: 421 WHDTCFVCAICQINLEGKTFYSKKDRPLCKSHAFSHV 457
>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
Length = 423
Score = 872 bits (2254), Expect = 0.0
Identities = 418/457 (91%), Positives = 419/457 (91%), Gaps = 34/457 (7%)
Query: 1 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS 60
MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS
Sbjct: 1 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS 60
Query: 61 LTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFG 120
LTHIEAQNKIRACGERLSLGLSRAQPVQSKPQK P
Sbjct: 61 LTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKVQTP----------------------- 97
Query: 121 APPPADSAPQQNGQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQ 180
+ QPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQ
Sbjct: 98 -----------DKQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQ 146
Query: 181 DPDEEHLKKSSQVPRTEAPAPASSTPQEPWPGPTAPSPTSRPPWAVDPAFAERYAPDKTS 240
DPDEEHLKKSSQVPRTEAPAPASSTPQEPWPGPTAPSPTSRPPWAVDPAFAERYAPDKTS
Sbjct: 147 DPDEEHLKKSSQVPRTEAPAPASSTPQEPWPGPTAPSPTSRPPWAVDPAFAERYAPDKTS 206
Query: 241 TVLTRHSQPATPTPLQSRTSIVQAAAGGVPGGGSNNGKTPVCHQCHKVIRGRYLVALGHA 300
TVLTRHSQPATPTPLQSRTSIVQAAAGGVPGGGSNNGKTPVCHQCHKVIRGRYLVALGHA
Sbjct: 207 TVLTRHSQPATPTPLQSRTSIVQAAAGGVPGGGSNNGKTPVCHQCHKVIRGRYLVALGHA 266
Query: 301 YHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEIMHALKMTW 360
YHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEIMHALKMTW
Sbjct: 267 YHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEIMHALKMTW 326
Query: 361 HVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFS 420
HVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFS
Sbjct: 327 HVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFS 386
Query: 421 WHDTCFVCAICQINLEGKTFYSKKDRPLCKSHAFSHV 457
WHDTCFVCAICQINLEGKTFYSKKDRPLCKSHAFSHV
Sbjct: 387 WHDTCFVCAICQINLEGKTFYSKKDRPLCKSHAFSHV 423
>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
Length = 487
Score = 426 bits (1095), Expect = e-119
Identities = 229/492 (46%), Positives = 298/492 (60%), Gaps = 45/492 (9%)
Query: 1 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS 60
M ++ V L GPAPWGFRLQGGKDFN+PL+IS L GGKAAQA V +GD VLSIDG NA
Sbjct: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
Query: 61 LTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFG 120
+TH+EAQNKI+ C L++ L RA + P+ P P T S + + A
Sbjct: 61 MTHLEAQNKIKGCTGSLNMTLQRAS---AAPKPEPVPV-QKPTVTSVCSETSQELAEGQR 116
Query: 121 APPPADSAPQQNGQPLRPLVP------------DASKQRLMENTEDWRPRPGTGQSRSFR 168
DS QQNG P + +V DASK+RL+E+TEDWRPR GT QSRSFR
Sbjct: 117 RGSQGDSK-QQNGPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFR 175
Query: 169 ILAHLTGTEFMQDPDEEHLKKS--SQVPRTEAPAPASSTPQEPWPGPTAPSPTSRPPWAV 226
ILA +TGTE +++ + ++ KK+ SQ P + + +ST P + SPTS P
Sbjct: 176 ILAQITGTEHLKESEADNTKKANNSQEPSPQLASSVASTRSMP---ESLDSPTSGRPGVT 232
Query: 227 DPAFAERYAPDKTSTVLTRHS--QPATPTPLQSRTSIVQAAAGGVPGGGSNNG------- 277
A + P ++ V+ S +P P R S +G V S G
Sbjct: 233 SLTAAAAFKPVGSTGVIKSPSWQRPNQGVPSTGRISNSATYSGSVAPANSALGQTQPSDQ 292
Query: 278 --------------KTPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEE 323
+TP+C C++VIRG +LVALG ++HPEEF C+ C + GF EE
Sbjct: 293 DTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEE 352
Query: 324 KGAIFCPPCYDVRYAPSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEE 383
KGA++C CY+ +AP C +C++KI GE++ ALK TWHV CF C AC PIRN F++E+
Sbjct: 353 KGALYCELCYEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLED 412
Query: 384 GVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSK 443
G PYCE DY +FGT CHGC+F I+AGD FLEALG++WHDTCFVC++C +LEG+TF+SK
Sbjct: 413 GEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSK 472
Query: 444 KDRPLCKSHAFS 455
KD+PLCK HA S
Sbjct: 473 KDKPLCKKHAHS 484
>gi|47157328 PDZ and LIM domain 7 isoform 4 [Homo sapiens]
Length = 222
Score = 390 bits (1002), Expect = e-108
Identities = 192/201 (95%), Positives = 194/201 (96%)
Query: 1 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS 60
MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS
Sbjct: 1 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS 60
Query: 61 LTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFG 120
LTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFG
Sbjct: 61 LTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFG 120
Query: 121 APPPADSAPQQNGQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQ 180
APPPADSAPQQNGQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQ
Sbjct: 121 APPPADSAPQQNGQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQ 180
Query: 181 DPDEEHLKKSSQVPRTEAPAP 201
DPDEEHLKKS + E +P
Sbjct: 181 DPDEEHLKKSREKYVLELQSP 201
>gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]
Length = 596
Score = 325 bits (832), Expect = 7e-89
Identities = 166/363 (45%), Positives = 221/363 (60%), Gaps = 40/363 (11%)
Query: 130 QQNGQPLRPLVP------------DASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTE 177
QQNG P + +V DASK+RL+E+TEDWRPR GT QSRSFRILA +TGTE
Sbjct: 234 QQNGPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTE 293
Query: 178 FMQDPDEEHLKKS--SQVPRTEAPAPASSTPQEPWPGPTAPSPTSRPPWAVDPAFAERYA 235
+++ + ++ KK+ SQ P + + +ST P + SPTS P A +
Sbjct: 294 HLKESEADNTKKANNSQEPSPQLASSVASTRSMP---ESLDSPTSGRPGVTSLTAAAAFK 350
Query: 236 PDKTSTVLTRHS--QPATPTPLQSRTSIVQAAAGGVPGGGSNNG---------------- 277
P ++ V+ S +P P R S +G V S G
Sbjct: 351 PVGSTGVIKSPSWQRPNQGVPSTGRISNSATYSGSVAPANSALGQTQPSDQDTLVQRAEH 410
Query: 278 -----KTPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPC 332
+TP+C C++VIRG +LVALG ++HPEEF C+ C + GF EEKGA++C C
Sbjct: 411 IPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELC 470
Query: 333 YDVRYAPSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDY 392
Y+ +AP C +C++KI GE++ ALK TWHV CF C AC PIRN F++E+G PYCE DY
Sbjct: 471 YEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDY 530
Query: 393 EKMFGTKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSH 452
+FGT CHGC+F I+AGD FLEALG++WHDTCFVC++C +LEG+TF+SKKD+PLCK H
Sbjct: 531 YALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCKKH 590
Query: 453 AFS 455
A S
Sbjct: 591 AHS 593
Score = 124 bits (310), Expect = 2e-28
Identities = 72/146 (49%), Positives = 89/146 (60%), Gaps = 19/146 (13%)
Query: 1 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS 60
M ++ V L GPAPWGFRLQGGKDFN+PL+IS L GGKAAQA V +GD VLSIDG NA
Sbjct: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
Query: 61 LTHIEAQNKIRACGERLSLGLSRAQ--------PVQS-------KPQKASAPAADPPRYT 105
+TH+EAQNKI+ C L++ L RA PVQ KP ++PA + T
Sbjct: 61 MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKGEPKEVVKPVPITSPAVS--KVT 118
Query: 106 FAPSVSLNKTARPFG--APPPADSAP 129
+++ NK RPFG + P S P
Sbjct: 119 STNNMAYNKAPRPFGSVSSPKVTSIP 144
>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
Length = 617
Score = 322 bits (826), Expect = 3e-88
Identities = 217/614 (35%), Positives = 277/614 (45%), Gaps = 166/614 (27%)
Query: 3 SFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLT 62
S+ V L GP PWGFRLQGGKDFN+PL+ISR+TPG KAAQ+ ++ GD V++IDG N ++T
Sbjct: 2 SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61
Query: 63 HIEAQNKIRACGERLSLGLSR----------AQPVQS-------KPQKASAPAADPPRYT 105
H+EAQNKI++ LSL L + A PVQ+ + ++PA +
Sbjct: 62 HLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKVVVNSPANADYQER 121
Query: 106 FAPSV---SLNKTARP--------------------------------FGAPPPADSAPQ 130
F PS S T +P A +
Sbjct: 122 FNPSALKDSALSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQAQGSDF 181
Query: 131 QNGQPLRPLVPDA----------SKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQ 180
P++ L D+ S+ + + ++W R QSRSFRILA +TGTEFMQ
Sbjct: 182 SGSLPIKDLAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQ 241
Query: 181 DPDEEHLKKS-------------SQVPRTE--------APAPA----------------- 202
DPDEE L++S S P T APAP
Sbjct: 242 DPDEEALRRSRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPV 301
Query: 203 -------------SSTPQEPWPGPT-APSP------------TSRPPWAVDPAFAERYAP 236
S TP P P P PSP T P A P+ A Y P
Sbjct: 302 PASTYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYNP 361
Query: 237 DKTSTVLTRHSQPATPTPLQSRTSIVQAAAGG----------VPGGGSNNGKTPVCHQCH 286
+ ++PA+ P + S Q A G +P GG TP Q
Sbjct: 362 APSVAYSGGPAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGP--AYTPAGPQVP 419
Query: 287 KVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRY--------- 337
+ RG A +C C V+ G F G + P + Y
Sbjct: 420 PLARGTVQRAERFPASSRTPLCGHCNNVI-RGPFLVAMGRSWHPEEFTCAYCKTSLADVC 478
Query: 338 ------------------APSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAF 379
AP CAKC KI GE+MHAL+ TWH CF CAACK P N F
Sbjct: 479 FVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLF 538
Query: 380 YMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKT 439
+ME+G PYCE+DY +F TKCHGCDF ++AGD+F+EALG +WHDTCF+CA+C +NLEG+
Sbjct: 539 HMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQP 598
Query: 440 FYSKKDRPLCKSHA 453
FYSKKDRPLCK HA
Sbjct: 599 FYSKKDRPLCKKHA 612
>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
Length = 727
Score = 300 bits (769), Expect = 1e-81
Identities = 162/410 (39%), Positives = 223/410 (54%), Gaps = 47/410 (11%)
Query: 86 PVQSKPQKASAP-AADPPRYTFAPSVSLNKTARPFGAPPPADSAPQQNGQPLRPLVP--- 141
P ++P A++P AA PP T A ++ + A PADS P+ P V
Sbjct: 318 PASAQPPAAASPSAASPPLATAAAHTAIASASTTAPASSPADS-PRPQASSYSPAVAASS 376
Query: 142 -DASKQRLMENTEDWRPRPGTGQSRSFR--ILAHLTGTEFMQDPDEEHLKKSSQVPRTEA 198
A+ E P+P + S R + + + + P + S P T +
Sbjct: 377 APATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASTYSPSPGANY----SPTPYTPS 432
Query: 199 PAPASS---------------TPQE-----PWPGPT---APS---------PTSRPPWAV 226
PAPA + TP P P P APS P SRPPW
Sbjct: 433 PAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYNPAPSVAYSGGPAEPASRPPWVT 492
Query: 227 DPAFAERYAPDKTSTVLTRHSQP-ATPTPLQSRTSIVQAAAGGVPGGGS--NNGKTPVCH 283
D +F++++AP K++T +++ + P P + + A G V + +TP+C
Sbjct: 493 DDSFSQKFAPGKSTTSISKQTLPRGGPAYTPAGPQVPPLARGTVQRAERFPASSRTPLCG 552
Query: 284 QCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAK 343
C+ VIRG +LVA+G ++HPEEF C+ C L + F EE+ ++C CY+ +AP CAK
Sbjct: 553 HCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAK 612
Query: 344 CKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGC 403
C KI GE+MHAL+ TWH CF CAACK P N F+ME+G PYCE+DY +F TKCHGC
Sbjct: 613 CNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGC 672
Query: 404 DFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSHA 453
DF ++AGD+F+EALG +WHDTCF+CA+C +NLEG+ FYSKKDRPLCK HA
Sbjct: 673 DFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKHA 722
Score = 114 bits (284), Expect = 2e-25
Identities = 63/141 (44%), Positives = 88/141 (62%), Gaps = 7/141 (4%)
Query: 3 SFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLT 62
S+ V L GP PWGFRLQGGKDFN+PL+ISR+TPG KAAQ+ ++ GD V++IDG N ++T
Sbjct: 2 SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61
Query: 63 HIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPP----RYTFAPSVSLNKTARP 118
H+EAQNKI++ LSL L +++ + P +AP P + P++ N +
Sbjct: 62 HLEAQNKIKSASYNLSLTLQKSK--RPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVA 119
Query: 119 FGAPPPADSAPQQNGQP-LRP 138
P A ++P G P LRP
Sbjct: 120 PSPSPEARASPGTPGTPELRP 140
Score = 69.7 bits (169), Expect = 5e-12
Identities = 53/152 (34%), Positives = 67/152 (44%), Gaps = 7/152 (4%)
Query: 118 PFGAPPPADSAPQQNGQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTE 177
P G+ P D A + ++ +K + ++W R QSRSFRILA +TGTE
Sbjct: 228 PGGSLPIKDLAVDSASPVYQAVIKSQNKPE--DEADEWARRSSNLQSRSFRILAQMTGTE 285
Query: 178 FMQDPDEEHLKKSSQVPRTEAPAPASSTPQEPWPGPTAPSPTSRPPWAVDPAFAERYAPD 237
FMQDPDEE L++SS P AP S P P P + P A P A A
Sbjct: 286 FMQDPDEEALRRSS-TPIEHAPVCTSQATTPLLPASAQP-PAAASPSAASPPLATAAAHT 343
Query: 238 ---KTSTVLTRHSQPATPTPLQSRTSIVQAAA 266
ST S +P P S S AA+
Sbjct: 344 AIASASTTAPASSPADSPRPQASSYSPAVAAS 375
>gi|58533161 PDZ and LIM domain 5 isoform e [Homo sapiens]
Length = 214
Score = 170 bits (431), Expect = 2e-42
Identities = 94/192 (48%), Positives = 120/192 (62%), Gaps = 7/192 (3%)
Query: 1 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS 60
M ++ V L GPAPWGFRLQGGKDFN+PL+IS L GGKAAQA V +GD VLSIDG NA
Sbjct: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
Query: 61 LTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFG 120
+TH+EAQNKI+ C L++ L RA + P+ P + T P P
Sbjct: 61 MTHLEAQNKIKGCTGSLNMTLQRA---SAAPKPEPVPVQKKTQVTNNPGT----VKIPPK 113
Query: 121 APPPADSAPQQNGQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQ 180
PP + P DASK+RL+E+TEDWRPR GT QSRSFRILA +TGTE ++
Sbjct: 114 RPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLK 173
Query: 181 DPDEEHLKKSSQ 192
+ + ++ KK+ +
Sbjct: 174 ESEADNTKKAKE 185
>gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens]
Length = 234
Score = 170 bits (431), Expect = 2e-42
Identities = 103/210 (49%), Positives = 128/210 (60%), Gaps = 23/210 (10%)
Query: 1 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS 60
M ++ V L GPAPWGFRLQGGKDFN+PL+IS L GGKAAQA V +GD VLSIDG NA
Sbjct: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
Query: 61 LTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFG 120
+TH+EAQNKI+ C L++ L RA S K P T S + + A
Sbjct: 61 MTHLEAQNKIKGCTGSLNMTLQRA----SAAPKPEPVPVQKPTVTSVCSETSQELAEGQR 116
Query: 121 APPPADSAPQQNGQ--PLRP-------------LVP---DASKQRLMENTEDWRPRPGTG 162
DS QQNG+ P RP VP DASK+RL+E+TEDWRPR GT
Sbjct: 117 RGSQGDS-KQQNGKIPPKRPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTT 175
Query: 163 QSRSFRILAHLTGTEFMQDPDEEHLKKSSQ 192
QSRSFRILA +TGTE +++ + ++ KK+ +
Sbjct: 176 QSRSFRILAQITGTEHLKESEADNTKKAKE 205
>gi|109638745 transforming growth factor beta 1 induced transcript 1
isoform 1 [Homo sapiens]
Length = 461
Score = 167 bits (422), Expect = 2e-41
Identities = 114/387 (29%), Positives = 164/387 (42%), Gaps = 42/387 (10%)
Query: 92 QKASAPAADPPRYTFAPSVSLNKTARPFGAPPPADSA--PQQNGQPLRPLVPDASKQRLM 149
++ + P PP Y P +++ G S ++ +P P P S +
Sbjct: 26 ERPAEPLTPPPSYGHQPQTGSGESSGASGDKDHLYSTVCKPRSPKPAAPAAPPFSSSSGV 85
Query: 150 ENTEDWRPRPGTGQSRSFRILAHLTGTEFMQDPDEEHLKKSSQVPRTEAPAPAS------ 203
GTG R+L L T+F + SS+V E S
Sbjct: 86 L---------GTGLCELDRLLQELNATQFNITDEIMSQFPSSKVASGEQKEDQSEDKKRP 136
Query: 204 STPQEPWPGPTAPSPTS------RPPWAVDPAFAERYAPDKTSTV-----LTRHSQPATP 252
S P P PG S TS R ++ + + P T T P+ P
Sbjct: 137 SLPSSPSPGLPKASATSATLELDRLMASLSDFRVQNHLPASGPTQPPVVSSTNEGSPSPP 196
Query: 253 TP-----LQSRTSIVQA--AAGGVPGGGSNNGKTPVCHQCHKVIRGRYLVALGHAYHPEE 305
P L + ++Q+ + GVP +C C+K I G+ + ALG A+HPE
Sbjct: 197 EPTGKGSLDTMLGLLQSDLSRRGVPTQAKG-----LCGSCNKPIAGQVVTALGRAWHPEH 251
Query: 306 FVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEIMHALKMTWHVHCF 365
FVC C L FFE+ GA FCP CY R++P C C + I +++ AL WH F
Sbjct: 252 FVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHPEHF 311
Query: 366 TCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFSWHDTC 425
C +C P + F+ EG PYC RD+ ++F +C GC I D ++ AL WH C
Sbjct: 312 CCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPI--LDNYISALSALWHPDC 369
Query: 426 FVCAICQINLEGKTFYSKKDRPLCKSH 452
FVC C G +F+ + RPLC++H
Sbjct: 370 FVCRECFAPFSGGSFFEHEGRPLCENH 396
Score = 112 bits (280), Expect = 7e-25
Identities = 55/172 (31%), Positives = 80/172 (46%), Gaps = 2/172 (1%)
Query: 279 TPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYA 338
+P C C++ IR + + ALG +HPE F C CG+ + GF E +G +C + +A
Sbjct: 284 SPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFA 343
Query: 339 PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGT 398
P C C+ I + AL WH CF C C P +F+ EG P CE + G+
Sbjct: 344 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 403
Query: 399 KCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCK 450
C C + R + ALG +H F C C L +F + +P C+
Sbjct: 404 LCATCGLPVTG--RCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQ 453
Score = 84.7 bits (208), Expect = 2e-16
Identities = 41/118 (34%), Positives = 55/118 (46%)
Query: 280 PVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 339
P C C I Y+ AL +HP+ FVC +C G FFE +G C + R
Sbjct: 344 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 403
Query: 340 SCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFG 397
CA C +TG + AL +H FTC C P+ +F G PYC+ + K+FG
Sbjct: 404 LCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLFG 461
>gi|21361591 transforming growth factor beta 1 induced transcript 1
isoform 2 [Homo sapiens]
Length = 444
Score = 167 bits (422), Expect = 2e-41
Identities = 114/387 (29%), Positives = 164/387 (42%), Gaps = 42/387 (10%)
Query: 92 QKASAPAADPPRYTFAPSVSLNKTARPFGAPPPADSA--PQQNGQPLRPLVPDASKQRLM 149
++ + P PP Y P +++ G S ++ +P P P S +
Sbjct: 9 ERPAEPLTPPPSYGHQPQTGSGESSGASGDKDHLYSTVCKPRSPKPAAPAAPPFSSSSGV 68
Query: 150 ENTEDWRPRPGTGQSRSFRILAHLTGTEFMQDPDEEHLKKSSQVPRTEAPAPAS------ 203
GTG R+L L T+F + SS+V E S
Sbjct: 69 L---------GTGLCELDRLLQELNATQFNITDEIMSQFPSSKVASGEQKEDQSEDKKRP 119
Query: 204 STPQEPWPGPTAPSPTS------RPPWAVDPAFAERYAPDKTSTV-----LTRHSQPATP 252
S P P PG S TS R ++ + + P T T P+ P
Sbjct: 120 SLPSSPSPGLPKASATSATLELDRLMASLSDFRVQNHLPASGPTQPPVVSSTNEGSPSPP 179
Query: 253 TP-----LQSRTSIVQA--AAGGVPGGGSNNGKTPVCHQCHKVIRGRYLVALGHAYHPEE 305
P L + ++Q+ + GVP +C C+K I G+ + ALG A+HPE
Sbjct: 180 EPTGKGSLDTMLGLLQSDLSRRGVPTQAKG-----LCGSCNKPIAGQVVTALGRAWHPEH 234
Query: 306 FVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEIMHALKMTWHVHCF 365
FVC C L FFE+ GA FCP CY R++P C C + I +++ AL WH F
Sbjct: 235 FVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHPEHF 294
Query: 366 TCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFSWHDTC 425
C +C P + F+ EG PYC RD+ ++F +C GC I D ++ AL WH C
Sbjct: 295 CCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPI--LDNYISALSALWHPDC 352
Query: 426 FVCAICQINLEGKTFYSKKDRPLCKSH 452
FVC C G +F+ + RPLC++H
Sbjct: 353 FVCRECFAPFSGGSFFEHEGRPLCENH 379
Score = 112 bits (280), Expect = 7e-25
Identities = 55/172 (31%), Positives = 80/172 (46%), Gaps = 2/172 (1%)
Query: 279 TPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYA 338
+P C C++ IR + + ALG +HPE F C CG+ + GF E +G +C + +A
Sbjct: 267 SPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFA 326
Query: 339 PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGT 398
P C C+ I + AL WH CF C C P +F+ EG P CE + G+
Sbjct: 327 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 386
Query: 399 KCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCK 450
C C + R + ALG +H F C C L +F + +P C+
Sbjct: 387 LCATCGLPVTG--RCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQ 436
Score = 84.7 bits (208), Expect = 2e-16
Identities = 41/118 (34%), Positives = 55/118 (46%)
Query: 280 PVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 339
P C C I Y+ AL +HP+ FVC +C G FFE +G C + R
Sbjct: 327 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 386
Query: 340 SCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFG 397
CA C +TG + AL +H FTC C P+ +F G PYC+ + K+FG
Sbjct: 387 LCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLFG 444
>gi|122056619 LIM domain binding 3 isoform 4 [Homo sapiens]
Length = 283
Score = 141 bits (356), Expect = 1e-33
Identities = 94/261 (36%), Positives = 129/261 (49%), Gaps = 62/261 (23%)
Query: 3 SFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLT 62
S+ V L GP PWGFRLQGGKDFN+PL+ISR+TPG KAAQ+ ++ GD V++IDG N ++T
Sbjct: 2 SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61
Query: 63 HIEAQNKIRACGERLSLGLSR----------AQPVQS-------KPQKASAPAADPPRYT 105
H+EAQNKI++ LSL L + A PVQ+ + ++PA +
Sbjct: 62 HLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKVVVNSPANADYQER 121
Query: 106 FAPSV---SLNKTARP--------------------------------FGAPPPADSAPQ 130
F PS S T +P A +
Sbjct: 122 FNPSALKDSALSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQAQGSDF 181
Query: 131 QNGQPLRPLVPDA----------SKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQ 180
P++ L D+ S+ + + ++W R QSRSFRILA +TGTEFMQ
Sbjct: 182 SGSLPIKDLAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQ 241
Query: 181 DPDEEHLKKSSQVPRTEAPAP 201
DPDEE L++S + TE +P
Sbjct: 242 DPDEEALRRSRERFETERNSP 262
>gi|221316659 leupaxin isoform 1 [Homo sapiens]
Length = 391
Score = 135 bits (339), Expect = 1e-31
Identities = 59/171 (34%), Positives = 88/171 (51%), Gaps = 2/171 (1%)
Query: 282 CHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSC 341
C C K I G+ + ALG ++HPE FVC+ C + + FFE G +CP Y ++P C
Sbjct: 157 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRC 216
Query: 342 AKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCH 401
A C I +++ A+ TWH F C+ C F+ ++ PYC +D+ MF KC
Sbjct: 217 AYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCG 276
Query: 402 GCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSH 452
GC+ + + +L A+ WH CFVC C + +F+ RP C+ H
Sbjct: 277 GCNRPV--LENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELH 325
Score = 122 bits (306), Expect = 7e-28
Identities = 56/172 (32%), Positives = 81/172 (47%), Gaps = 2/172 (1%)
Query: 279 TPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYA 338
+P C C I + L A+ +HPE F CS CG+V GF E+ +C + ++
Sbjct: 213 SPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 272
Query: 339 PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGT 398
P C C + + + A+ WH CF C C T +F+ +G P+CE Y GT
Sbjct: 273 PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT 332
Query: 399 KCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCK 450
CHGC I R + A+G+ +H FVCA C L F + D+ C+
Sbjct: 333 LCHGCGQPITG--RCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQ 382
Score = 77.8 bits (190), Expect = 2e-14
Identities = 39/118 (33%), Positives = 54/118 (45%)
Query: 279 TPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYA 338
+P C C++ + YL A+ +HPE FVC C G FFE G FC Y R
Sbjct: 272 SPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRG 331
Query: 339 PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMF 396
C C + ITG + A+ +H F CA C T + F + YC+ + K+F
Sbjct: 332 TLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
>gi|4758670 leupaxin isoform 2 [Homo sapiens]
Length = 386
Score = 135 bits (339), Expect = 1e-31
Identities = 59/171 (34%), Positives = 88/171 (51%), Gaps = 2/171 (1%)
Query: 282 CHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSC 341
C C K I G+ + ALG ++HPE FVC+ C + + FFE G +CP Y ++P C
Sbjct: 152 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRC 211
Query: 342 AKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCH 401
A C I +++ A+ TWH F C+ C F+ ++ PYC +D+ MF KC
Sbjct: 212 AYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCG 271
Query: 402 GCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSH 452
GC+ + + +L A+ WH CFVC C + +F+ RP C+ H
Sbjct: 272 GCNRPV--LENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELH 320
Score = 122 bits (306), Expect = 7e-28
Identities = 56/172 (32%), Positives = 81/172 (47%), Gaps = 2/172 (1%)
Query: 279 TPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYA 338
+P C C I + L A+ +HPE F CS CG+V GF E+ +C + ++
Sbjct: 208 SPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 267
Query: 339 PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGT 398
P C C + + + A+ WH CF C C T +F+ +G P+CE Y GT
Sbjct: 268 PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT 327
Query: 399 KCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCK 450
CHGC I R + A+G+ +H FVCA C L F + D+ C+
Sbjct: 328 LCHGCGQPITG--RCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQ 377
Score = 77.8 bits (190), Expect = 2e-14
Identities = 39/118 (33%), Positives = 54/118 (45%)
Query: 279 TPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYA 338
+P C C++ + YL A+ +HPE FVC C G FFE G FC Y R
Sbjct: 267 SPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRG 326
Query: 339 PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMF 396
C C + ITG + A+ +H F CA C T + F + YC+ + K+F
Sbjct: 327 TLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 384
>gi|170932518 paxillin isoform 3 [Homo sapiens]
Length = 424
Score = 131 bits (330), Expect = 1e-30
Identities = 62/173 (35%), Positives = 86/173 (49%), Gaps = 2/173 (1%)
Query: 279 TPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYA 338
+P C+ C+ I + + AL +HPE F C+QCG GF E+ G +C Y +A
Sbjct: 247 SPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 306
Query: 339 PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGT 398
P C C + I + AL WH CF C C TP N +F+ +G PYCE Y + G+
Sbjct: 307 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 366
Query: 399 KCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKS 451
C GC I R + A+ +H FVCA C L TF + D+P C++
Sbjct: 367 LCSGCQKPITG--RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQN 417
Score = 127 bits (318), Expect = 3e-29
Identities = 60/172 (34%), Positives = 84/172 (48%), Gaps = 2/172 (1%)
Query: 281 VCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPS 340
VC C K I G+ + A+G +HPE FVC+ C + + FFE G +C Y ++P
Sbjct: 190 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 249
Query: 341 CAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKC 400
C C I +++ AL TWH F CA C F+ ++G YC +DY MF KC
Sbjct: 250 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKC 309
Query: 401 HGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSH 452
GC I + ++ AL WH CFVC C +F+ +P C+ H
Sbjct: 310 GGCARAI--LENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVH 359
Score = 89.0 bits (219), Expect = 8e-18
Identities = 40/114 (35%), Positives = 60/114 (52%), Gaps = 2/114 (1%)
Query: 341 CAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKC 400
C CKK I G+++ A+ TWH F C C+ I +R F+ +G PYCE+DY +F +C
Sbjct: 191 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRC 250
Query: 401 HGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSHAF 454
+ C+ I D+ + AL +WH F CA C + F+ K + C+ F
Sbjct: 251 YYCNGPIL--DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYF 302
Score = 83.2 bits (204), Expect = 5e-16
Identities = 40/117 (34%), Positives = 55/117 (47%)
Query: 280 PVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 339
P C C + I Y+ AL +HPE FVC +C G FFE G +C Y R
Sbjct: 307 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 366
Query: 340 SCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMF 396
C+ C+K ITG + A+ +H F CA C + F + PYC+ + K+F
Sbjct: 367 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423
>gi|170932516 paxillin isoform 2 [Homo sapiens]
Length = 557
Score = 131 bits (330), Expect = 1e-30
Identities = 62/173 (35%), Positives = 86/173 (49%), Gaps = 2/173 (1%)
Query: 279 TPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYA 338
+P C+ C+ I + + AL +HPE F C+QCG GF E+ G +C Y +A
Sbjct: 380 SPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 439
Query: 339 PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGT 398
P C C + I + AL WH CF C C TP N +F+ +G PYCE Y + G+
Sbjct: 440 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 499
Query: 399 KCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKS 451
C GC I R + A+ +H FVCA C L TF + D+P C++
Sbjct: 500 LCSGCQKPITG--RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQN 550
Score = 127 bits (318), Expect = 3e-29
Identities = 60/172 (34%), Positives = 84/172 (48%), Gaps = 2/172 (1%)
Query: 281 VCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPS 340
VC C K I G+ + A+G +HPE FVC+ C + + FFE G +C Y ++P
Sbjct: 323 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 382
Query: 341 CAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKC 400
C C I +++ AL TWH F CA C F+ ++G YC +DY MF KC
Sbjct: 383 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKC 442
Query: 401 HGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSH 452
GC I + ++ AL WH CFVC C +F+ +P C+ H
Sbjct: 443 GGCARAI--LENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVH 492
Score = 89.0 bits (219), Expect = 8e-18
Identities = 40/114 (35%), Positives = 60/114 (52%), Gaps = 2/114 (1%)
Query: 341 CAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKC 400
C CKK I G+++ A+ TWH F C C+ I +R F+ +G PYCE+DY +F +C
Sbjct: 324 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRC 383
Query: 401 HGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSHAF 454
+ C+ I D+ + AL +WH F CA C + F+ K + C+ F
Sbjct: 384 YYCNGPIL--DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYF 435
Score = 83.2 bits (204), Expect = 5e-16
Identities = 40/117 (34%), Positives = 55/117 (47%)
Query: 280 PVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 339
P C C + I Y+ AL +HPE FVC +C G FFE G +C Y R
Sbjct: 440 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 499
Query: 340 SCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMF 396
C+ C+K ITG + A+ +H F CA C + F + PYC+ + K+F
Sbjct: 500 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
>gi|170932514 paxillin isoform 1 [Homo sapiens]
Length = 591
Score = 131 bits (330), Expect = 1e-30
Identities = 62/173 (35%), Positives = 86/173 (49%), Gaps = 2/173 (1%)
Query: 279 TPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYA 338
+P C+ C+ I + + AL +HPE F C+QCG GF E+ G +C Y +A
Sbjct: 414 SPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 473
Query: 339 PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGT 398
P C C + I + AL WH CF C C TP N +F+ +G PYCE Y + G+
Sbjct: 474 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 533
Query: 399 KCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKS 451
C GC I R + A+ +H FVCA C L TF + D+P C++
Sbjct: 534 LCSGCQKPITG--RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQN 584
Score = 127 bits (318), Expect = 3e-29
Identities = 60/172 (34%), Positives = 84/172 (48%), Gaps = 2/172 (1%)
Query: 281 VCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPS 340
VC C K I G+ + A+G +HPE FVC+ C + + FFE G +C Y ++P
Sbjct: 357 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 416
Query: 341 CAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKC 400
C C I +++ AL TWH F CA C F+ ++G YC +DY MF KC
Sbjct: 417 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKC 476
Query: 401 HGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSH 452
GC I + ++ AL WH CFVC C +F+ +P C+ H
Sbjct: 477 GGCARAI--LENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVH 526
Score = 89.0 bits (219), Expect = 8e-18
Identities = 40/114 (35%), Positives = 60/114 (52%), Gaps = 2/114 (1%)
Query: 341 CAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKC 400
C CKK I G+++ A+ TWH F C C+ I +R F+ +G PYCE+DY +F +C
Sbjct: 358 CGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRC 417
Query: 401 HGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSHAF 454
+ C+ I D+ + AL +WH F CA C + F+ K + C+ F
Sbjct: 418 YYCNGPIL--DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYF 469
Score = 83.2 bits (204), Expect = 5e-16
Identities = 40/117 (34%), Positives = 55/117 (47%)
Query: 280 PVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 339
P C C + I Y+ AL +HPE FVC +C G FFE G +C Y R
Sbjct: 474 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 533
Query: 340 SCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMF 396
C+ C+K ITG + A+ +H F CA C + F + PYC+ + K+F
Sbjct: 534 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 590
>gi|238859658 LIM and senescent cell antigen-like domains 2 isoform
1 [Homo sapiens]
Length = 363
Score = 131 bits (329), Expect = 1e-30
Identities = 64/171 (37%), Positives = 94/171 (54%), Gaps = 4/171 (2%)
Query: 281 VCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPS 340
+C +CH VI + L+ AYHP+ F C+ CGK L E KG ++C PC+D P
Sbjct: 161 ICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAR-ELKGELYCLPCHDKMGVPI 219
Query: 341 CAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKC 400
C C++ I G +++AL WHV F CA C+ P Y ++G+ YCE Y ++FG C
Sbjct: 220 CGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVC 279
Query: 401 HGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKD-RPLCK 450
+ C I+ GD + AL +W +CF C+ C L K + + D +P+CK
Sbjct: 280 YNCSHVIE-GD-VVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCK 328
Score = 87.8 bits (216), Expect = 2e-17
Identities = 40/116 (34%), Positives = 63/116 (54%), Gaps = 1/116 (0%)
Query: 280 PVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 339
P+C C + I GR + ALG +H E FVC++C K +E+KG +C Y+ +
Sbjct: 218 PICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGD 277
Query: 340 SCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYME-EGVPYCERDYEK 394
C C I G+++ AL W V CF+C+ C + + + ++E + P C+R YEK
Sbjct: 278 VCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333
Score = 75.9 bits (185), Expect = 7e-14
Identities = 46/158 (29%), Positives = 68/158 (43%), Gaps = 9/158 (5%)
Query: 281 VCHQCHKVIRG--RYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYA 338
VC +C R + + G YH FVC+QC + EG F+E +G +C + + +A
Sbjct: 36 VCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFA 95
Query: 339 PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYC----ERDYEK 394
P C C + I G ++ A+ WH CF C C + + F G C R+ K
Sbjct: 96 PCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAK 155
Query: 395 MFGTK-CHGCDFKIDAGDRFLEALGFSWHDTCFVCAIC 431
G C C ID ++ L ++H F C C
Sbjct: 156 GLGKYICQRCHLVID--EQPLMFRSDAYHPDHFNCTHC 191
Score = 35.0 bits (79), Expect = 0.14
Identities = 15/51 (29%), Positives = 23/51 (45%)
Query: 400 CHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCK 450
C C + +R + + G +H+ CFVCA C FY + R C+
Sbjct: 37 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCE 87
>gi|238776788 LIM and senescent cell antigen-like domains 2 isoform
5 [Homo sapiens]
Length = 336
Score = 131 bits (329), Expect = 1e-30
Identities = 64/171 (37%), Positives = 94/171 (54%), Gaps = 4/171 (2%)
Query: 281 VCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPS 340
+C +CH VI + L+ AYHP+ F C+ CGK L E KG ++C PC+D P
Sbjct: 134 ICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAR-ELKGELYCLPCHDKMGVPI 192
Query: 341 CAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKC 400
C C++ I G +++AL WHV F CA C+ P Y ++G+ YCE Y ++FG C
Sbjct: 193 CGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVC 252
Query: 401 HGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKD-RPLCK 450
+ C I+ GD + AL +W +CF C+ C L K + + D +P+CK
Sbjct: 253 YNCSHVIE-GD-VVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCK 301
Score = 87.8 bits (216), Expect = 2e-17
Identities = 40/116 (34%), Positives = 63/116 (54%), Gaps = 1/116 (0%)
Query: 280 PVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 339
P+C C + I GR + ALG +H E FVC++C K +E+KG +C Y+ +
Sbjct: 191 PICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGD 250
Query: 340 SCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYME-EGVPYCERDYEK 394
C C I G+++ AL W V CF+C+ C + + + ++E + P C+R YEK
Sbjct: 251 VCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 306
Score = 75.9 bits (185), Expect = 7e-14
Identities = 46/158 (29%), Positives = 68/158 (43%), Gaps = 9/158 (5%)
Query: 281 VCHQCHKVIRG--RYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYA 338
VC +C R + + G YH FVC+QC + EG F+E +G +C + + +A
Sbjct: 9 VCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFA 68
Query: 339 PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYC----ERDYEK 394
P C C + I G ++ A+ WH CF C C + + F G C R+ K
Sbjct: 69 PCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAK 128
Query: 395 MFGTK-CHGCDFKIDAGDRFLEALGFSWHDTCFVCAIC 431
G C C ID ++ L ++H F C C
Sbjct: 129 GLGKYICQRCHLVID--EQPLMFRSDAYHPDHFNCTHC 164
Score = 35.0 bits (79), Expect = 0.14
Identities = 15/51 (29%), Positives = 23/51 (45%)
Query: 400 CHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCK 450
C C + +R + + G +H+ CFVCA C FY + R C+
Sbjct: 10 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCE 60
>gi|238776786 LIM and senescent cell antigen-like domains 2 isoform
3 [Homo sapiens]
Length = 341
Score = 131 bits (329), Expect = 1e-30
Identities = 64/171 (37%), Positives = 94/171 (54%), Gaps = 4/171 (2%)
Query: 281 VCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPS 340
+C +CH VI + L+ AYHP+ F C+ CGK L E KG ++C PC+D P
Sbjct: 139 ICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAR-ELKGELYCLPCHDKMGVPI 197
Query: 341 CAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKC 400
C C++ I G +++AL WHV F CA C+ P Y ++G+ YCE Y ++FG C
Sbjct: 198 CGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVC 257
Query: 401 HGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKD-RPLCK 450
+ C I+ GD + AL +W +CF C+ C L K + + D +P+CK
Sbjct: 258 YNCSHVIE-GD-VVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCK 306
Score = 87.8 bits (216), Expect = 2e-17
Identities = 40/116 (34%), Positives = 63/116 (54%), Gaps = 1/116 (0%)
Query: 280 PVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 339
P+C C + I GR + ALG +H E FVC++C K +E+KG +C Y+ +
Sbjct: 196 PICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGD 255
Query: 340 SCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYME-EGVPYCERDYEK 394
C C I G+++ AL W V CF+C+ C + + + ++E + P C+R YEK
Sbjct: 256 VCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 311
Score = 75.9 bits (185), Expect = 7e-14
Identities = 46/158 (29%), Positives = 68/158 (43%), Gaps = 9/158 (5%)
Query: 281 VCHQCHKVIRG--RYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYA 338
VC +C R + + G YH FVC+QC + EG F+E +G +C + + +A
Sbjct: 14 VCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFA 73
Query: 339 PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYC----ERDYEK 394
P C C + I G ++ A+ WH CF C C + + F G C R+ K
Sbjct: 74 PCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAK 133
Query: 395 MFGTK-CHGCDFKIDAGDRFLEALGFSWHDTCFVCAIC 431
G C C ID ++ L ++H F C C
Sbjct: 134 GLGKYICQRCHLVID--EQPLMFRSDAYHPDHFNCTHC 169
Score = 35.0 bits (79), Expect = 0.14
Identities = 15/51 (29%), Positives = 23/51 (45%)
Query: 400 CHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCK 450
C C + +R + + G +H+ CFVCA C FY + R C+
Sbjct: 15 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCE 65
>gi|40804748 LIM and senescent cell antigen-like domains 2 isoform 2
[Homo sapiens]
Length = 365
Score = 131 bits (329), Expect = 1e-30
Identities = 64/171 (37%), Positives = 94/171 (54%), Gaps = 4/171 (2%)
Query: 281 VCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPS 340
+C +CH VI + L+ AYHP+ F C+ CGK L E KG ++C PC+D P
Sbjct: 163 ICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEAR-ELKGELYCLPCHDKMGVPI 221
Query: 341 CAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKC 400
C C++ I G +++AL WHV F CA C+ P Y ++G+ YCE Y ++FG C
Sbjct: 222 CGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVC 281
Query: 401 HGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKD-RPLCK 450
+ C I+ GD + AL +W +CF C+ C L K + + D +P+CK
Sbjct: 282 YNCSHVIE-GD-VVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCK 330
Score = 87.8 bits (216), Expect = 2e-17
Identities = 40/116 (34%), Positives = 63/116 (54%), Gaps = 1/116 (0%)
Query: 280 PVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 339
P+C C + I GR + ALG +H E FVC++C K +E+KG +C Y+ +
Sbjct: 220 PICGACRRPIEGRVVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGD 279
Query: 340 SCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYME-EGVPYCERDYEK 394
C C I G+++ AL W V CF+C+ C + + + ++E + P C+R YEK
Sbjct: 280 VCYNCSHVIEGDVVSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 335
Score = 75.9 bits (185), Expect = 7e-14
Identities = 46/158 (29%), Positives = 68/158 (43%), Gaps = 9/158 (5%)
Query: 281 VCHQCHKVIRG--RYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYA 338
VC +C R + + G YH FVC+QC + EG F+E +G +C + + +A
Sbjct: 38 VCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFA 97
Query: 339 PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYC----ERDYEK 394
P C C + I G ++ A+ WH CF C C + + F G C R+ K
Sbjct: 98 PCCGSCGEFIIGRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAK 157
Query: 395 MFGTK-CHGCDFKIDAGDRFLEALGFSWHDTCFVCAIC 431
G C C ID ++ L ++H F C C
Sbjct: 158 GLGKYICQRCHLVID--EQPLMFRSDAYHPDHFNCTHC 193
Score = 35.0 bits (79), Expect = 0.14
Identities = 15/51 (29%), Positives = 23/51 (45%)
Query: 400 CHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCK 450
C C + +R + + G +H+ CFVCA C FY + R C+
Sbjct: 39 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCE 89
>gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo
sapiens]
Length = 325
Score = 127 bits (320), Expect = 2e-29
Identities = 60/171 (35%), Positives = 91/171 (53%), Gaps = 4/171 (2%)
Query: 281 VCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPS 340
+C +CH +I + L+ YHP+ F C+ CGK L E KG ++C PC+D P
Sbjct: 134 ICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADAR-ELKGELYCLPCHDKMGVPI 192
Query: 341 CAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKC 400
C C++ I G +++A+ WHV F CA C+ P Y +G+ YCE Y ++FG C
Sbjct: 193 CGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVC 252
Query: 401 HGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKD-RPLCK 450
C+ ++ GD + AL +W CF C+ C L K + + D +P+CK
Sbjct: 253 FHCN-RVIEGD-VVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCK 301
Score = 88.2 bits (217), Expect = 1e-17
Identities = 39/116 (33%), Positives = 63/116 (54%), Gaps = 1/116 (0%)
Query: 280 PVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 339
P+C C + I GR + A+G +H E FVC++C K +E KG +C Y+ +
Sbjct: 191 PICGACRRPIEGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGD 250
Query: 340 SCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYME-EGVPYCERDYEK 394
C C + I G+++ AL W V+CF C+ C T + + ++E + P C++ YEK
Sbjct: 251 VCFHCNRVIEGDVVSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEK 306
Score = 79.7 bits (195), Expect = 5e-15
Identities = 53/216 (24%), Positives = 79/216 (36%), Gaps = 61/216 (28%)
Query: 298 GHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEIMHALK 357
G YH + FVC+QC + EG F+E +G +C + + +AP C +C + I G ++ A+
Sbjct: 28 GELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIKAMN 87
Query: 358 MTWHVHCFTCAACKTPIRNRAFYMEEGVPYCE--------RDYEKMFGTKCH-------- 401
+WH CF C C+ + + F G C R K KCH
Sbjct: 88 NSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPL 147
Query: 402 -----------------GCDFKIDAGD----------------------------RFLEA 416
G + DA + R + A
Sbjct: 148 IFKNDPYHPDHFNCANCGKELTADARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNA 207
Query: 417 LGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSH 452
+G WH FVCA C+ G Y +K C++H
Sbjct: 208 MGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETH 243
Score = 32.0 bits (71), Expect = 1.2
Identities = 14/51 (27%), Positives = 22/51 (43%)
Query: 400 CHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCK 450
C C ++ + + G +H+ CFVCA C FY + R C+
Sbjct: 10 CERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCE 60
>gi|13994151 PDZ and LIM domain 1 [Homo sapiens]
Length = 329
Score = 124 bits (311), Expect = 2e-28
Identities = 95/338 (28%), Positives = 147/338 (43%), Gaps = 40/338 (11%)
Query: 1 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS 60
M + ++ L+GP PWGFRL GGKDF PL+ISR+TPG KAA A + +GD + +IDGEN +
Sbjct: 1 MTTQQIDLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSN 60
Query: 61 LTHIEAQNKIRACGERLSLGLSRAQ--------PVQSKPQKASAPAADPPRYTFAPSVSL 112
+TH+EAQN+I+ C + L+L ++R++ + K A P+ +
Sbjct: 61 MTHLEAQNRIKGCTDNLTLTVARSEHKVWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAH 120
Query: 113 NKTARPFGAPPPADSAPQQ-NGQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILA 171
N++A PF A P + + + Q P +S+ N +G + R L
Sbjct: 121 NRSAMPFTASPASSTTARVITNQYNNPAGLYSSENISNFNNALESKTAASGVEANSRPLD 180
Query: 172 HLTGTEFMQDPDEEHLKKSSQVPRTEAPAPASSTPQEPWPGPTAPSPTSRPPWAVDPAFA 231
H Q P + K S+V + + P P + V
Sbjct: 181 HA------QPPSSLVIDKESEVYKMLQEKQELNEP-----------PKQSTSFLVLQEIL 223
Query: 232 ERYAPDKTSTVLTRHSQPATPTPLQSRTSIVQAAAGGVPGGGSNNGKTPVCHQCHKVIRG 291
E P P+ +S + V A + N K P+C +C I G
Sbjct: 224 ES----------EEKGDPNKPSGFRSVKAPVTKVAASI----GNAQKLPMCDKCGTGIVG 269
Query: 292 RYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFC 329
++ HPE +VC+ CG L++ G F + I+C
Sbjct: 270 VFVKLRDRHRHPECYVCTDCGTNLKQKGHFFVEDQIYC 307
Score = 36.6 bits (83), Expect = 0.049
Identities = 15/52 (28%), Positives = 22/52 (42%)
Query: 339 PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCER 390
P C KC I G + H C+ C C T ++ + + E YCE+
Sbjct: 258 PMCDKCGTGIVGVFVKLRDRHRHPECYVCTDCGTNLKQKGHFFVEDQIYCEK 309
Score = 32.0 bits (71), Expect = 1.2
Identities = 13/36 (36%), Positives = 19/36 (52%)
Query: 422 HDTCFVCAICQINLEGKTFYSKKDRPLCKSHAFSHV 457
H C+VC C NL+ K + +D+ C+ HA V
Sbjct: 280 HPECYVCTDCGTNLKQKGHFFVEDQIYCEKHARERV 315
>gi|19923181 PDZ and LIM domain 4 isoform 1 [Homo sapiens]
Length = 330
Score = 120 bits (301), Expect = 3e-27
Identities = 109/363 (30%), Positives = 153/363 (42%), Gaps = 84/363 (23%)
Query: 6 VVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLTHIE 65
V L GP+PWGFRL GG+DF+ PL+ISR+ G KAA A + GD + +I+GE+ +TH+E
Sbjct: 5 VTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELMTHLE 64
Query: 66 AQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFGAPPPA 125
AQN+I+ C + L+L +SR P+ S P+A P
Sbjct: 65 AQNRIKGCHDHLTLSVSR-------PEGRSWPSA------------------------PD 93
Query: 126 DSAPQQNGQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQDPDEE 185
DS Q + + P + D S T RP GTG TG E D
Sbjct: 94 DSKAQAHRIHIDPEIQDGSP------TTSRRP-SGTG-----------TGPE---DGRPS 132
Query: 186 HLKKSSQVPRTEAPAPASSTPQEPWPGPTAPSPTSRPPWAVDPAFAERYAPD-------K 238
Q PR P P + + + P + S PP + DPA + D +
Sbjct: 133 LGSPYGQPPR--FPVPHNGSSEATLPAQMSTLHVSPPP-SADPARGLPRSRDCRVDLGSE 189
Query: 239 TSTVLTRHSQPATPTPLQSRT-----SIVQAAAGG---VPGGGSNNGKT----------- 279
+L ++P P QS + +++A GG PGG N T
Sbjct: 190 VYRMLREPAEPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPRNLKPTASKLGAPLSGL 249
Query: 280 ---PVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVR 336
P C +C I G + A YHPE F+CS CG L++ G+F ++C R
Sbjct: 250 QGLPECTRCGHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGYFFLDERLYCESHAKAR 309
Query: 337 YAP 339
P
Sbjct: 310 VKP 312
Score = 37.0 bits (84), Expect = 0.037
Identities = 21/75 (28%), Positives = 37/75 (49%), Gaps = 14/75 (18%)
Query: 383 EGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYS 442
+G+P C R + GT + A D+ +H CF+C+ C +NL+ + ++
Sbjct: 250 QGLPECTRCGHGIVGTI-------VKARDKL-------YHPECFMCSDCGLNLKQRGYFF 295
Query: 443 KKDRPLCKSHAFSHV 457
+R C+SHA + V
Sbjct: 296 LDERLYCESHAKARV 310
>gi|166235178 PDZ and LIM domain protein 3 isoform b [Homo sapiens]
Length = 316
Score = 120 bits (301), Expect = 3e-27
Identities = 94/324 (29%), Positives = 142/324 (43%), Gaps = 35/324 (10%)
Query: 6 VVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLTHIE 65
V+L GPAPWGFRL GG DFN PL I+R+TPG KAA A + GD +L+IDG S+TH +
Sbjct: 5 VILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHAD 64
Query: 66 AQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFGAPPPA 125
AQ++I+A +L L + R + PQ + A P + ++L + F P
Sbjct: 65 AQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFK------INLESEPQEF---KPI 115
Query: 126 DSAPQQNGQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQDPDEE 185
+A + QP K++++ S S+ L T +QD
Sbjct: 116 GTAHNRRAQPFVAAANIDDKRQVV--------------SASYNSPIGLYSTSNIQDALHG 161
Query: 186 HLKKSSQVPRTEAPAPASSTPQEPWPGPTAPSPTSRPPWAVDPAFAERYAPDKTSTVLTR 245
L+ +P + P +S P E + P P + + +
Sbjct: 162 QLR--GLIPSSPQNEPTASVPPESDVYRMLHDNRNEP---TQPRQSGSFRVLQGMVDDGS 216
Query: 246 HSQPATPTPLQSRTSIVQAAAGGVPGGGSNNGKTPVCHQCHKVIRGRYLVALGHAYHPEE 305
+PA T V+A V GG + P+C +C I G + A HPE
Sbjct: 217 DDRPA-------GTRSVRAPVTKVHGGSGGAQRMPLCDKCGSGIVGAVVKARDKYRHPEC 269
Query: 306 FVCSQCGKVLEEGGFFEEKGAIFC 329
FVC+ C L++ G+F +G ++C
Sbjct: 270 FVCADCNLNLKQKGYFFIEGELYC 293
Score = 44.3 bits (103), Expect = 2e-04
Identities = 18/51 (35%), Positives = 25/51 (49%)
Query: 339 PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCE 389
P C KC I G ++ A H CF CA C ++ + ++ EG YCE
Sbjct: 244 PLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCE 294
Score = 34.7 bits (78), Expect = 0.18
Identities = 13/32 (40%), Positives = 20/32 (62%)
Query: 422 HDTCFVCAICQINLEGKTFYSKKDRPLCKSHA 453
H CFVCA C +NL+ K ++ + C++HA
Sbjct: 266 HPECFVCADCNLNLKQKGYFFIEGELYCETHA 297
>gi|54112385 four and a half LIM domains 3 [Homo sapiens]
Length = 280
Score = 115 bits (289), Expect = 6e-26
Identities = 56/173 (32%), Positives = 83/173 (47%), Gaps = 4/173 (2%)
Query: 282 CHQCHKVIR--GRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 339
C C + + R L G +H F+CS C + L F +KGA +C PCY+ ++AP
Sbjct: 101 CSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAP 160
Query: 340 SCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTK 399
CA+C K +T + WH C C C+TP+ + F + PYC + ++F K
Sbjct: 161 RCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPK 220
Query: 400 CHGCDFKID--AGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCK 450
C C I G +++ WH CF CA C +L G+ F D+ LC+
Sbjct: 221 CSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQ 273
Score = 94.4 bits (233), Expect = 2e-19
Identities = 49/172 (28%), Positives = 77/172 (44%), Gaps = 6/172 (3%)
Query: 282 CHQCHKVIR--GRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 339
C +C ++I R L +H F C +C + L + F + + C CY ++
Sbjct: 40 CAECQQLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSS 99
Query: 340 SCAKCKKKIT--GEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFG 397
C+ C + + + TWH HCF C+ C+ P+ +R+F ++G YC YE F
Sbjct: 100 QCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFA 159
Query: 398 TKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLC 449
+C C + G + WH C VC CQ L G+ F S+ + P C
Sbjct: 160 PRCARCSKTLTQGG--VTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYC 209
Score = 87.4 bits (215), Expect = 2e-17
Identities = 42/148 (28%), Positives = 69/148 (46%), Gaps = 2/148 (1%)
Query: 304 EEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEIMHALKMTWHVH 363
E F C++C + L + + +C PCYD +A +CA+C++ I + H H
Sbjct: 3 ESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFH 62
Query: 364 --CFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFSW 421
CF C C+ + + F ++ C Y F ++C C + G R LE G +W
Sbjct: 63 EGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTW 122
Query: 422 HDTCFVCAICQINLEGKTFYSKKDRPLC 449
H+ CF+C+ C+ L ++F K C
Sbjct: 123 HEHCFLCSGCEQPLGSRSFVPDKGAHYC 150
Score = 58.5 bits (140), Expect = 1e-08
Identities = 31/118 (26%), Positives = 49/118 (41%), Gaps = 4/118 (3%)
Query: 276 NGKTPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDV 335
N P C +C K + + +H E VC+ C L F +C C+
Sbjct: 156 NKFAPRCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGE 215
Query: 336 RYAPSCAKCKKKIT----GEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCE 389
+AP C+ CK+ I G+ + WH +CF+CA C T + + F + C+
Sbjct: 216 LFAPKCSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQ 273
>gi|122056617 LIM domain binding 3 isoform 3 [Homo sapiens]
Length = 330
Score = 114 bits (284), Expect = 2e-25
Identities = 63/141 (44%), Positives = 88/141 (62%), Gaps = 7/141 (4%)
Query: 3 SFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLT 62
S+ V L GP PWGFRLQGGKDFN+PL+ISR+TPG KAAQ+ ++ GD V++IDG N ++T
Sbjct: 2 SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61
Query: 63 HIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPP----RYTFAPSVSLNKTARP 118
H+EAQNKI++ LSL L +++ + P +AP P + P++ N +
Sbjct: 62 HLEAQNKIKSASYNLSLTLQKSK--RPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVA 119
Query: 119 FGAPPPADSAPQQNGQP-LRP 138
P A ++P G P LRP
Sbjct: 120 PSPSPEARASPGTPGTPELRP 140
Score = 61.2 bits (147), Expect = 2e-09
Identities = 34/84 (40%), Positives = 47/84 (55%), Gaps = 2/84 (2%)
Query: 118 PFGAPPPADSAPQQNGQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTE 177
P G+ P D A + ++ +K + ++W R QSRSFRILA +TGTE
Sbjct: 228 PGGSLPIKDLAVDSASPVYQAVIKSQNKPE--DEADEWARRSSNLQSRSFRILAQMTGTE 285
Query: 178 FMQDPDEEHLKKSSQVPRTEAPAP 201
FMQDPDEE L++S + TE +P
Sbjct: 286 FMQDPDEEALRRSRERFETERNSP 309
>gi|7662330 actin binding LIM protein family, member 3 [Homo
sapiens]
Length = 683
Score = 111 bits (278), Expect = 1e-24
Identities = 71/187 (37%), Positives = 86/187 (45%), Gaps = 18/187 (9%)
Query: 282 CHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGA-IFCPPCYD------ 334
C C I G + ALG YHP+ FVCS C K G G C C
Sbjct: 82 CDSCRDFITGEVISALGRTYHPKCFVCSLCRKPFPIGDKVTFSGKECVCQTCSQSMASSK 141
Query: 335 ---VRYAPSCAKCKKKIT-GEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCER 390
+R CA CK++I G+ + AL WHV CF C C I + ++GVPYCE
Sbjct: 142 PIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQTCSV-ILTGEYISKDGVPYCES 200
Query: 391 DYEKMFGTKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAIC-QINLEGKTFY---SKKDR 446
DY FG KC CD I R LEA G +H TC C C Q+ EG+ Y S+
Sbjct: 201 DYHAQFGIKCETCDRYISG--RVLEAGGKHYHPTCARCVRCHQMFTEGEEMYLTGSEVWH 258
Query: 447 PLCKSHA 453
P+CK A
Sbjct: 259 PICKQAA 265
Score = 94.4 bits (233), Expect = 2e-19
Identities = 61/194 (31%), Positives = 85/194 (43%), Gaps = 19/194 (9%)
Query: 270 PGGGSNNGKTPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFC 329
P G SN C++C +G + + +H F C CG L + GFF + C
Sbjct: 14 PRGSSN---VIQCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSGFFFKNQEYIC 70
Query: 330 PPCYDVRYAPSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPI---RNRAFYMEEGVP 386
Y Y C C+ ITGE++ AL T+H CF C+ C+ P F +E V
Sbjct: 71 TQDYQQLYGTRCDSCRDFITGEVISALGRTYHPKCFVCSLCRKPFPIGDKVTFSGKECV- 129
Query: 387 YCERDYEKMFGTK---------CHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEG 437
C+ + M +K C GC +I G L AL WH +CF C C + L G
Sbjct: 130 -CQTCSQSMASSKPIKIRGPSHCAGCKEEIKHGQSLL-ALDKQWHVSCFKCQTCSVILTG 187
Query: 438 KTFYSKKDRPLCKS 451
+ + SK P C+S
Sbjct: 188 E-YISKDGVPYCES 200
>gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 109 bits (272), Expect = 6e-24
Identities = 56/176 (31%), Positives = 78/176 (44%), Gaps = 5/176 (2%)
Query: 279 TPVCHQCHK-VIRGRYLVAL-GHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVR 336
+P C C K ++ G V G +H + F CS C +V+ G FF + +C C++ +
Sbjct: 98 SPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETK 157
Query: 337 YAPSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMF 396
+A C KC K IT + WH CF C C + + F E YC Y+
Sbjct: 158 FAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFV 217
Query: 397 GTKCHGCDFKIDA---GDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLC 449
KC GC I G + G SWHD CF C C +NL K F +++ C
Sbjct: 218 AKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 273
Score = 87.0 bits (214), Expect = 3e-17
Identities = 45/148 (30%), Positives = 69/148 (46%), Gaps = 2/148 (1%)
Query: 304 EEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEI--MHALKMTWH 361
E+F C C L+ + ++ G C C+D A +C +C+K I + +H WH
Sbjct: 3 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
Query: 362 VHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFSW 421
CF CA C P+ N F ++ C + + KC GC I AGD+ +E G W
Sbjct: 63 DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
Query: 422 HDTCFVCAICQINLEGKTFYSKKDRPLC 449
H CF C+ C+ + +F+ K + C
Sbjct: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYC 150
Score = 76.3 bits (186), Expect = 6e-14
Identities = 51/172 (29%), Positives = 72/172 (41%), Gaps = 6/172 (3%)
Query: 282 CHQCHKVIRG--RYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 339
C +C K I + + +H F C++C L F + I C C +P
Sbjct: 40 CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99
Query: 340 SCAKCKKKI-TGEIMHALKMT-WHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFG 397
C C K I G+ K T WH CFTC+ CK I +F+ + YC +E F
Sbjct: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 159
Query: 398 TKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLC 449
C C+ I +G + WH CFVC C L G+ F + +D+ C
Sbjct: 160 KHCVKCNKAITSGG--ITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 209
>gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 109 bits (272), Expect = 6e-24
Identities = 56/176 (31%), Positives = 78/176 (44%), Gaps = 5/176 (2%)
Query: 279 TPVCHQCHK-VIRGRYLVAL-GHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVR 336
+P C C K ++ G V G +H + F CS C +V+ G FF + +C C++ +
Sbjct: 98 SPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETK 157
Query: 337 YAPSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMF 396
+A C KC K IT + WH CF C C + + F E YC Y+
Sbjct: 158 FAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFV 217
Query: 397 GTKCHGCDFKIDA---GDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLC 449
KC GC I G + G SWHD CF C C +NL K F +++ C
Sbjct: 218 AKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 273
Score = 87.0 bits (214), Expect = 3e-17
Identities = 45/148 (30%), Positives = 69/148 (46%), Gaps = 2/148 (1%)
Query: 304 EEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEI--MHALKMTWH 361
E+F C C L+ + ++ G C C+D A +C +C+K I + +H WH
Sbjct: 3 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
Query: 362 VHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFSW 421
CF CA C P+ N F ++ C + + KC GC I AGD+ +E G W
Sbjct: 63 DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
Query: 422 HDTCFVCAICQINLEGKTFYSKKDRPLC 449
H CF C+ C+ + +F+ K + C
Sbjct: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYC 150
Score = 76.3 bits (186), Expect = 6e-14
Identities = 51/172 (29%), Positives = 72/172 (41%), Gaps = 6/172 (3%)
Query: 282 CHQCHKVIRG--RYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 339
C +C K I + + +H F C++C L F + I C C +P
Sbjct: 40 CVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSP 99
Query: 340 SCAKCKKKI-TGEIMHALKMT-WHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFG 397
C C K I G+ K T WH CFTC+ CK I +F+ + YC +E F
Sbjct: 100 KCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFA 159
Query: 398 TKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLC 449
C C+ I +G + WH CFVC C L G+ F + +D+ C
Sbjct: 160 KHCVKCNKAITSGG--ITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 209
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.435
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,637,103
Number of Sequences: 37866
Number of extensions: 1342557
Number of successful extensions: 12533
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 245
Number of HSP's successfully gapped in prelim test: 615
Number of HSP's that attempted gapping in prelim test: 9042
Number of HSP's gapped (non-prelim): 2988
length of query: 457
length of database: 18,247,518
effective HSP length: 106
effective length of query: 351
effective length of database: 14,233,722
effective search space: 4996036422
effective search space used: 4996036422
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.