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Search of human proteins with 114796626
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|114796626 solute carrier family 16, member 8 [Homo sapiens]
(504 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|114796626 solute carrier family 16, member 8 [Homo sapiens] 995 0.0
gi|109288010 solute carrier family 16, member 3 [Homo sapiens] 517 e-146
gi|109288012 solute carrier family 16, member 3 [Homo sapiens] 517 e-146
gi|4759112 solute carrier family 16, member 3 [Homo sapiens] 517 e-146
gi|24431958 solute carrier family 16, member 7 [Homo sapiens] 403 e-112
gi|115583685 solute carrier family 16, member 1 [Homo sapiens] 363 e-100
gi|4759116 solute carrier family 16, member 5 [Homo sapiens] 310 2e-84
gi|23503293 solute carrier family 16, member 11 [Homo sapiens] 256 3e-68
gi|169217968 PREDICTED: similar to solute carrier family 16, mem... 256 4e-68
gi|157041233 solute carrier family 16 (monocarboxylic acid trans... 249 5e-66
gi|42475555 monocarboxylate transporter 13 [Homo sapiens] 237 2e-62
gi|40789261 solute carrier family 16, member 6 [Homo sapiens] 209 6e-54
gi|18699730 solute carrier family 16, member 10 [Homo sapiens] 182 8e-46
gi|41327156 solute carrier family 16 (monocarboxylic acid transp... 166 5e-41
gi|5730045 solute carrier family 16, member 2 [Homo sapiens] 163 3e-40
gi|4759114 solute carrier family 16, member 4 [Homo sapiens] 149 8e-36
gi|34916028 solute carrier family 16 (monocarboxylic acid transp... 135 1e-31
gi|154350196 vesicular nucleotide transporter SLC17A9 [Homo sapi... 36 0.072
gi|20336188 paired basic amino acid cleaving system 4 isoform e ... 35 0.16
gi|20336186 paired basic amino acid cleaving system 4 isoform c ... 35 0.16
gi|27894285 paired basic amino acid cleaving system 4 isoform f ... 35 0.16
gi|20336190 paired basic amino acid cleaving system 4 isoform d ... 35 0.16
gi|20336184 paired basic amino acid cleaving system 4 isoform h ... 35 0.16
gi|20336182 paired basic amino acid cleaving system 4 isoform g ... 35 0.16
gi|4505577 paired basic amino acid cleaving system 4 isoform a p... 35 0.16
gi|20336180 paired basic amino acid cleaving system 4 isoform b ... 35 0.16
gi|4885441 solute carrier family 17 (sodium phosphate), member 4... 33 0.46
gi|42476325 solute carrier family 18 (vesicular monoamine), memb... 33 0.61
gi|215272392 solute carrier family 18 (vesicular monoamine), mem... 33 0.61
gi|215272390 solute carrier family 18 (vesicular monoamine), mem... 33 0.61
>gi|114796626 solute carrier family 16, member 8 [Homo sapiens]
Length = 504
Score = 995 bits (2572), Expect = 0.0
Identities = 504/504 (100%), Positives = 504/504 (100%)
Query: 1 MGAGGPRRGEGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAWV 60
MGAGGPRRGEGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAWV
Sbjct: 1 MGAGGPRRGEGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAWV 60
Query: 61 SSIMLAMLYGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTG 120
SSIMLAMLYGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTG
Sbjct: 61 SSIMLAMLYGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTG 120
Query: 121 LGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLL 180
LGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLL
Sbjct: 121 LGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLL 180
Query: 181 GGLLLHCCACGAVMRPPPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREASPRVRPRR 240
GGLLLHCCACGAVMRPPPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREASPRVRPRR
Sbjct: 181 GGLLLHCCACGAVMRPPPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREASPRVRPRR 240
Query: 241 RLLDLAVCTDRAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLSIVGFVDI 300
RLLDLAVCTDRAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLSIVGFVDI
Sbjct: 241 RLLDLAVCTDRAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLSIVGFVDI 300
Query: 301 VARPACGALAGLARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAFGLSYGMV 360
VARPACGALAGLARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAFGLSYGMV
Sbjct: 301 VARPACGALAGLARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAFGLSYGMV 360
Query: 361 GALQFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIFYLAGSEV 420
GALQFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIFYLAGSEV
Sbjct: 361 GALQFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIFYLAGSEV 420
Query: 421 ALAGVFMAVATNCCLRCAKAAPSGPGTEGGASDTEDAEAEGDSEPLPVVAEEPGNLEALE 480
ALAGVFMAVATNCCLRCAKAAPSGPGTEGGASDTEDAEAEGDSEPLPVVAEEPGNLEALE
Sbjct: 421 ALAGVFMAVATNCCLRCAKAAPSGPGTEGGASDTEDAEAEGDSEPLPVVAEEPGNLEALE 480
Query: 481 VLSARGEPTEPEIEARPRLAAESV 504
VLSARGEPTEPEIEARPRLAAESV
Sbjct: 481 VLSARGEPTEPEIEARPRLAAESV 504
>gi|109288010 solute carrier family 16, member 3 [Homo sapiens]
Length = 465
Score = 517 bits (1331), Expect = e-146
Identities = 265/462 (57%), Positives = 322/462 (69%), Gaps = 46/462 (9%)
Query: 4 GGPRRGEGP-----PDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTA 58
GG EGP PDGGWGW VL CFV+TGF+Y FPKAVSVFF+ L+++F GYSDTA
Sbjct: 2 GGAVVDEGPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTA 61
Query: 59 WVSSIMLAMLYGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVL 118
W+SSI+LAMLYGTGP+ S+ V RFGCRPVML GGL AS GM+ ASF ++++YLT GV+
Sbjct: 62 WISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVI 121
Query: 119 TGLGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFL 178
TGLGLALNFQPSLIML YF +RRP+ANGLAAAGSPVFL ALSPLGQ L +R+GWRGGFL
Sbjct: 122 TGLGLALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFL 181
Query: 179 LLGGLLLHCCACGAVMRP-----PPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREAS 233
+LGGLLL+CC C A+MRP PG GP
Sbjct: 182 ILGGLLLNCCVCAALMRPLVVTAQPGSGP------------------------------- 210
Query: 234 PRVRPRRRLLDLAVCTDRAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLS 293
RP RRLLDL+V DR F +YAV +M LGLFVP + +V+YAKD GVPDT AAFLL+
Sbjct: 211 --PRPSRRLLDLSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLT 268
Query: 294 IVGFVDIVARPACGALAGLARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAF 353
I+GF+DI ARPA G +AGL ++RP+ YLFS ++ NGL DL+ + A YG LV FC+ F
Sbjct: 269 ILGFIDIFARPAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFF 328
Query: 354 GLSYGMVGALQFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIF 413
G+SYGMVGALQFEVLMA VG +F SA+GLVLL+EA AVL+GPPS G+L+D Y +F
Sbjct: 329 GISYGMVGALQFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVF 388
Query: 414 YLAGSEVALAGVFMAVATNCCLRCAKAAPSGPGTEGGASDTE 455
LAG+EV + + + + C+R P P E A++ E
Sbjct: 389 ILAGAEVLTSSLILLLGNFFCIR---KKPKEPQPEVAAAEEE 427
>gi|109288012 solute carrier family 16, member 3 [Homo sapiens]
Length = 465
Score = 517 bits (1331), Expect = e-146
Identities = 265/462 (57%), Positives = 322/462 (69%), Gaps = 46/462 (9%)
Query: 4 GGPRRGEGP-----PDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTA 58
GG EGP PDGGWGW VL CFV+TGF+Y FPKAVSVFF+ L+++F GYSDTA
Sbjct: 2 GGAVVDEGPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTA 61
Query: 59 WVSSIMLAMLYGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVL 118
W+SSI+LAMLYGTGP+ S+ V RFGCRPVML GGL AS GM+ ASF ++++YLT GV+
Sbjct: 62 WISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVI 121
Query: 119 TGLGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFL 178
TGLGLALNFQPSLIML YF +RRP+ANGLAAAGSPVFL ALSPLGQ L +R+GWRGGFL
Sbjct: 122 TGLGLALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFL 181
Query: 179 LLGGLLLHCCACGAVMRP-----PPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREAS 233
+LGGLLL+CC C A+MRP PG GP
Sbjct: 182 ILGGLLLNCCVCAALMRPLVVTAQPGSGP------------------------------- 210
Query: 234 PRVRPRRRLLDLAVCTDRAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLS 293
RP RRLLDL+V DR F +YAV +M LGLFVP + +V+YAKD GVPDT AAFLL+
Sbjct: 211 --PRPSRRLLDLSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLT 268
Query: 294 IVGFVDIVARPACGALAGLARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAF 353
I+GF+DI ARPA G +AGL ++RP+ YLFS ++ NGL DL+ + A YG LV FC+ F
Sbjct: 269 ILGFIDIFARPAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFF 328
Query: 354 GLSYGMVGALQFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIF 413
G+SYGMVGALQFEVLMA VG +F SA+GLVLL+EA AVL+GPPS G+L+D Y +F
Sbjct: 329 GISYGMVGALQFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVF 388
Query: 414 YLAGSEVALAGVFMAVATNCCLRCAKAAPSGPGTEGGASDTE 455
LAG+EV + + + + C+R P P E A++ E
Sbjct: 389 ILAGAEVLTSSLILLLGNFFCIR---KKPKEPQPEVAAAEEE 427
>gi|4759112 solute carrier family 16, member 3 [Homo sapiens]
Length = 465
Score = 517 bits (1331), Expect = e-146
Identities = 265/462 (57%), Positives = 322/462 (69%), Gaps = 46/462 (9%)
Query: 4 GGPRRGEGP-----PDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTA 58
GG EGP PDGGWGW VL CFV+TGF+Y FPKAVSVFF+ L+++F GYSDTA
Sbjct: 2 GGAVVDEGPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTA 61
Query: 59 WVSSIMLAMLYGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVL 118
W+SSI+LAMLYGTGP+ S+ V RFGCRPVML GGL AS GM+ ASF ++++YLT GV+
Sbjct: 62 WISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVI 121
Query: 119 TGLGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFL 178
TGLGLALNFQPSLIML YF +RRP+ANGLAAAGSPVFL ALSPLGQ L +R+GWRGGFL
Sbjct: 122 TGLGLALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFL 181
Query: 179 LLGGLLLHCCACGAVMRP-----PPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREAS 233
+LGGLLL+CC C A+MRP PG GP
Sbjct: 182 ILGGLLLNCCVCAALMRPLVVTAQPGSGP------------------------------- 210
Query: 234 PRVRPRRRLLDLAVCTDRAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLS 293
RP RRLLDL+V DR F +YAV +M LGLFVP + +V+YAKD GVPDT AAFLL+
Sbjct: 211 --PRPSRRLLDLSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLT 268
Query: 294 IVGFVDIVARPACGALAGLARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAF 353
I+GF+DI ARPA G +AGL ++RP+ YLFS ++ NGL DL+ + A YG LV FC+ F
Sbjct: 269 ILGFIDIFARPAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFF 328
Query: 354 GLSYGMVGALQFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIF 413
G+SYGMVGALQFEVLMA VG +F SA+GLVLL+EA AVL+GPPS G+L+D Y +F
Sbjct: 329 GISYGMVGALQFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVF 388
Query: 414 YLAGSEVALAGVFMAVATNCCLRCAKAAPSGPGTEGGASDTE 455
LAG+EV + + + + C+R P P E A++ E
Sbjct: 389 ILAGAEVLTSSLILLLGNFFCIR---KKPKEPQPEVAAAEEE 427
>gi|24431958 solute carrier family 16, member 7 [Homo sapiens]
Length = 478
Score = 403 bits (1035), Expect = e-112
Identities = 198/418 (47%), Positives = 278/418 (66%), Gaps = 7/418 (1%)
Query: 12 PPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAWVSSIMLAMLYGT 71
PPDGGWGW+V+GA F+ GF+Y FPKAV+VFF+ + + F YS+ AW+SSIMLA++Y
Sbjct: 13 PPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAWISSIMLAVMYAG 72
Query: 72 GPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGLALNFQPSL 131
GPVSS+LV ++G RPV++AGGLL GM+LASF++ +++LYLT G +TGLGLA N QP+L
Sbjct: 73 GPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPAL 132
Query: 132 IMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLLGGLLLHCCACG 191
++G YF R+RP+ANGLA AGSPVFLS+L+P Q L FGW+G FL+LG LLL+ C G
Sbjct: 133 TIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAG 192
Query: 192 AVMRPPPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREASPRVRPRRRLLDLAVCTDR 251
++MR P GP + ++ + G+ E D + +++ + LD ++ R
Sbjct: 193 SLMR-PLGP------NQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFSLFKHR 245
Query: 252 AFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLSIVGFVDIVARPACGALAG 311
F +Y +M LG F P I L YAKD G+ + AAFLLS++ FVD+ ARP+ G +A
Sbjct: 246 GFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSVGLIAN 305
Query: 312 LARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAFGLSYGMVGALQFEVLMAA 371
+RP + Y FS A++ NG+ L A+ Y +LV + V FGL +G V ++ FE LM
Sbjct: 306 SKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDL 365
Query: 372 VGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIFYLAGSEVALAGVFMAV 429
VGAPRF SA+GLV +VE VL+GPP AG+LVD+ Y+ ++ G+ V A V++ +
Sbjct: 366 VGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLI 423
>gi|115583685 solute carrier family 16, member 1 [Homo sapiens]
Length = 500
Score = 363 bits (933), Expect = e-100
Identities = 194/481 (40%), Positives = 282/481 (58%), Gaps = 13/481 (2%)
Query: 4 GGPRRGEGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAWVSSI 63
GGP G PPDGGWGW V+ F+ GF+Y FPK+++VFF+ + F A S+ +W+SSI
Sbjct: 6 GGPV-GYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSI 64
Query: 64 MLAMLYGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGL 123
MLA++YG GP+SSILV ++G R VM+ GG L+ G+I ASF + +LY+ GV+ GLGL
Sbjct: 65 MLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGL 124
Query: 124 ALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLLGGL 183
A N P+L M+G YF +RRPLANGLA AGSPVFL L+PL Q FGWRG FL+LGGL
Sbjct: 125 AFNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGL 184
Query: 184 LLHCCACGAVMRPPPGPGP----RPRRDSAGDRAGDAPGEAEADGAGLQLREASPRVRPR 239
LL+CC GA+MR P GP P + + ++ ++AG + + + A L P+ R
Sbjct: 185 LLNCCVAGALMR-PIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQEKR 243
Query: 240 ------RRLLDLAVCTDRAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLS 293
+ LDL + T R F +Y +M GLF P + L +Y K +AFLLS
Sbjct: 244 SVFQTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAFLLS 303
Query: 294 IVGFVDIVARPACGALAGLARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAF 353
I+ FVD+VARP+ G +A +RP + Y F+ +++ANG+ + + + +Y + F
Sbjct: 304 ILAFVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYAGFF 363
Query: 354 GLSYGMVGALQFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIF 413
G ++G + ++ FE LM VG RF SA+GLV +VE VL+GPP GRL D+ +Y+ +
Sbjct: 364 GFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTY 423
Query: 414 YLAGSEVALAGVFMAVATNCCLR-CAKAAPSGPGTEGGASDTEDAEAEGDSEPLPVVAEE 472
+ G + ++G+++ + R AK + + + + G + AE
Sbjct: 424 WACGVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNEVTKAAES 483
Query: 473 P 473
P
Sbjct: 484 P 484
>gi|4759116 solute carrier family 16, member 5 [Homo sapiens]
Length = 505
Score = 310 bits (795), Expect = 2e-84
Identities = 172/415 (41%), Positives = 235/415 (56%), Gaps = 12/415 (2%)
Query: 14 DGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAWVSSIMLAMLYGTGP 73
DG W WVVL A V G GFP + +FF L +F A S+T+W SI+ A+L+ GP
Sbjct: 9 DGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNSETSWFPSILTAVLHMAGP 68
Query: 74 VSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGLALNFQPSLIM 133
+ SILV RFGCR ++ GG+LAS GM+ +SF+ L +LY TAG +TGLG+ +FQ S+ +
Sbjct: 69 LCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSITV 128
Query: 134 LGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLLGGLLLHCCACGAV 193
LG YF RRR LAN LA+ G + ++ L + LLE GWRG FL+ GG+ LHCC CGA+
Sbjct: 129 LGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAI 188
Query: 194 MRP-PPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREASPRVRPRRRLLDLAVCTDRA 252
+RP P + A G A G +Q A +R +
Sbjct: 189 IRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILR-----------HNTG 237
Query: 253 FAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLSIVGFVDIVARPACGALAGL 312
+ VY + LG +P + LV YA V + AA L+SI+GF +I RP G +AG
Sbjct: 238 YCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGR 297
Query: 313 ARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAFGLSYGMVGALQFEVLMAAV 372
H YLFSLALL NGLT+L A + + LV +C+A+ +S +GAL F+VLM V
Sbjct: 298 PAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIV 357
Query: 373 GAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIFYLAGSEVALAGVFM 427
+FP ALGL +++ A LI PP AG L+D N+ +FY++ + A +FM
Sbjct: 358 PMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFM 412
>gi|23503293 solute carrier family 16, member 11 [Homo sapiens]
Length = 471
Score = 256 bits (655), Expect = 3e-68
Identities = 167/438 (38%), Positives = 223/438 (50%), Gaps = 36/438 (8%)
Query: 11 GPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAWVSSIMLAMLYG 70
GPPDGGWGWVV A F + G +YG +++ + F L FD DTAW+S++ LA+
Sbjct: 31 GPPDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTAWISALALAVQQA 90
Query: 71 TGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGLALNFQPS 130
PV S L TR+G RPV++ GG+LAS G + ++FA+ LL LYL G+L G G AL F P+
Sbjct: 91 ASPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFGWALVFAPA 150
Query: 131 LIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLLGGLLLHCCAC 190
L L YF RRR LA GLA G+ L+P Q LL+ FGWRG LLLG + LH C
Sbjct: 151 LGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPC 210
Query: 191 GAVMRPPPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREASPRVRPRRRLLDLAVCTD 250
GA++ P PG P AP + GL L T
Sbjct: 211 GALLLPLVLPGDPP-----------APPRSPLAALGLSL------------------FTR 241
Query: 251 RAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLSIVGFVDIVARPACGALA 310
RAF+++A+ L+ G FVP + L +A D G+ AA ++++ D AR CG LA
Sbjct: 242 RAFSIFALGTALVGGGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLA 301
Query: 311 G-----LARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAFGLSYGMVGALQF 365
L RL L L L GL + G L+A VA+GLS G L F
Sbjct: 302 DQGWVPLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVF 361
Query: 366 EVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIFYLAGSEVALAGV 425
VL VG A GLV+++ + L+GPP +G L D ++ F L+GS + L+G
Sbjct: 362 GVLPGLVGVGGVVQATGLVMMLMSLGGLLGPPLSGFLRDETGDFTASFLLSGS-LILSGS 420
Query: 426 FMAVATNCCL-RCAKAAP 442
F+ + L C A+P
Sbjct: 421 FIYIGLPRALPSCGPASP 438
>gi|169217968 PREDICTED: similar to solute carrier family 16, member
5 [Homo sapiens]
Length = 453
Score = 256 bits (653), Expect = 4e-68
Identities = 146/356 (41%), Positives = 201/356 (56%), Gaps = 12/356 (3%)
Query: 73 PVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGLALNFQPSLI 132
P+ SILV RFGCR ++ GG+LAS GM+ +SF+ L +LY TAG +TGLG+ +FQ S+
Sbjct: 16 PLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSIT 75
Query: 133 MLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLLGGLLLHCCACGA 192
+LG YF RRR LAN LA+ G + ++ L + LLE GWRG FL+ GG+ LHCC CGA
Sbjct: 76 VLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGA 135
Query: 193 VMRP-PPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREASPRVRPRRRLLDLAVCTDR 251
++RP P + A G A G +Q A +R +
Sbjct: 136 IIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILR-----------HNT 184
Query: 252 AFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLSIVGFVDIVARPACGALAG 311
+ VY + LG +P + LV YA V + AA L+SI+GF +I RP G +AG
Sbjct: 185 GYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAG 244
Query: 312 LARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAFGLSYGMVGALQFEVLMAA 371
H YLFSLALL NGLT+L A + + LV +C+A+ +S +GAL F+VLM
Sbjct: 245 RPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDI 304
Query: 372 VGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIFYLAGSEVALAGVFM 427
V +FP ALGL +++ A LI PP AG L+D N+ +FY++ + A +FM
Sbjct: 305 VPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFM 360
>gi|157041233 solute carrier family 16 (monocarboxylic acid
transporters), member 12 [Homo sapiens]
Length = 486
Score = 249 bits (635), Expect = 5e-66
Identities = 156/435 (35%), Positives = 217/435 (49%), Gaps = 24/435 (5%)
Query: 8 RGEGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAWVSSIMLAM 67
R PPDGGWGW+++ CF+VT + +S+FF F Y+ TAW+ SI+ +
Sbjct: 8 RSTSPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFTQDYAQTAWIHSIVDCV 67
Query: 68 LYGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGLALNF 127
P+ S++ C+ ++ GGLLAS G+IL+SFAT L LYLT GVLTGLG AL +
Sbjct: 68 TMLCAPLGSVVSNHLSCQVGIMLGGLLASTGLILSSFATSLKHLYLTLGVLTGLGFALCY 127
Query: 128 QPSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLLGGLLLHC 187
P++ M+G YF RR+ LA G+A +GS + L+P+ Q L+E+F WRG L+LGG +L+
Sbjct: 128 SPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNL 187
Query: 188 CACGAVMRPPPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREASPRVRPRRRLLDLAV 247
C CGA+MRP + D + D ++ SP + +
Sbjct: 188 CVCGALMRP-----ITLKEDHTTPEQNHVCRTQKED-----IKRVSPYSSLTKEWAQTCL 237
Query: 248 C----------TDRAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLSIVGF 297
C F V AV+ MA G + LV YA GV AAFL+SI+G
Sbjct: 238 CCCLQQEYSFLLMSDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHQQAAFLMSILGV 297
Query: 298 VDIVARPACGALAGLARLR--PHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAFGL 355
+DI+ G L L+ +V YLF++ + +GL L +S LV F FG
Sbjct: 298 IDIIGNITFGWLTDRRCLKNYQYVCYLFAVGM--DGLCYLCLPMLQSLPLLVPFSCTFGY 355
Query: 356 SYGMVGALQFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIFYL 415
G L V VG SALG+V + A L+ PP AGRLVD +Y F L
Sbjct: 356 FDGAYVTLIPVVTTEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGRLVDTTGSYTAAFLL 415
Query: 416 AGSEVALAGVFMAVA 430
G + + V + A
Sbjct: 416 CGFSMIFSSVLLGFA 430
>gi|42475555 monocarboxylate transporter 13 [Homo sapiens]
Length = 426
Score = 237 bits (605), Expect = 2e-62
Identities = 166/453 (36%), Positives = 229/453 (50%), Gaps = 44/453 (9%)
Query: 7 RRGEGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAWVSSIMLA 66
RR E PPDGGWGWVV+ + F + +G ++ VFF + F+ + +W++SI +A
Sbjct: 3 RRTE-PPDGGWGWVVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQAARVSWIASIGIA 61
Query: 67 MLYGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGLALN 126
+ PV S L T+FG RPV++ GG+LA+ GM+LASFAT L LYL+ G+L+G G AL
Sbjct: 62 VQQFGSPVGSALSTKFGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALT 121
Query: 127 FQPSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLLGGLLLH 186
F P+L L YF RRR LA GLA G + +P Q LL + WRG LL+ L LH
Sbjct: 122 FAPTLACLSCYFSRRRSLATGLALTGVGLSSFTFAPFFQWLLSHYAWRGSLLLVSALSLH 181
Query: 187 CCACGAVMRPPPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREASPRVRPRRRLLDLA 246
ACGA++RPP L E PR +L L
Sbjct: 182 LVACGALLRPP------------------------------SLAEDPAVGGPRAQLTSLL 211
Query: 247 VCTDRAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLSIVGFVDIVARPAC 306
F Y V L+ G F+P + LV + +D AAFLLS+V D+V R
Sbjct: 212 --HHGPFLRYTVALTLINTGYFIPYLHLVAHLQDLDWDPLPAAFLLSVVAISDLVGRVVS 269
Query: 307 GALAGLARLRPHVPYLFSLALLANGLTDLSSAR---ARSYGALVAFCVAFGLSYGMVGAL 363
G L G A P + L +L LT +S A A++ ALVA VA+G + G + L
Sbjct: 270 GWL-GDAVPGP----VTRLLMLWTTLTGVSLALFPVAQAPTALVALAVAYGFTSGALAPL 324
Query: 364 QFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIFYLAGS-EVAL 422
F VL +G R LGL+ ++E+ L+GPP +G L DV NY F +AG+ ++
Sbjct: 325 AFSVLPELIGTRRIYCGLGLLQMIESIGGLLGPPLSGYLRDVTGNYTASFVVAGAFLLSG 384
Query: 423 AGVFMAVATNCCLRCAKAAPSGPGTEGGASDTE 455
+G+ + + C + P TE A DT+
Sbjct: 385 SGILLTLPHFFCFSTTTSGPQDLVTE--ALDTK 415
>gi|40789261 solute carrier family 16, member 6 [Homo sapiens]
Length = 523
Score = 209 bits (531), Expect = 6e-54
Identities = 139/469 (29%), Positives = 220/469 (46%), Gaps = 39/469 (8%)
Query: 13 PDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAWVSSIMLAMLYGTG 72
PDGGWGW V + F V F YG K VFF LM F+ S +W+ SI + +L +
Sbjct: 19 PDGGWGWAVAVSFFFVEVFTYGIIKTFGVFFNDLMDSFNESNSRISWIISICVFVLTFSA 78
Query: 73 PVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGLALNFQPSLI 132
P++++L RFG R V++ GGLL S GM+ ASF+ + +Y+ G+++GLG +F P++
Sbjct: 79 PLATVLSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVAIGIISGLGYCFSFLPTVT 138
Query: 133 MLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLLGGLLLHCCACGA 192
+L YF +RR + +A+ G + A +P L ER GWR L +G L L+ GA
Sbjct: 139 ILSQYFGKRRSIVTAVASTGECFAVFAFAPAIMALKERIGWRYSLLFVGLLQLNIVIFGA 198
Query: 193 VMRPPPGPGPRPRRDSAGDRAGDAPGEAEAD---------GAGLQLR------------- 230
++RP GP + + +A E + +G++L
Sbjct: 199 LLRPIFIRGPASPKIVIQENRKEAQYMLENEKTRTSIDSIDSGVELTTSPKNVPTHTNLE 258
Query: 231 ------------EASPRVRPRRR-LLDLAVCTDRAFAVYAVTKFLMALGLFVPAILLVNY 277
+ SPR ++ LLD ++ +++F YA+ LG F P++ ++
Sbjct: 259 LEPKADMQQVLVKTSPRPSEKKAPLLDFSILKEKSFICYALFGLFATLGFFAPSLYIIPL 318
Query: 278 AKDAGVPDTDAAFLLSIVGFVDIVARPACGALAGLARLRPHVPYLFSLALLANGLTDLSS 337
G+ AAFLLS + ++ R G + +R L + LL L +
Sbjct: 319 GISLGIDQDRAAFLLSTMAIAEVFGRIGAGFVLNREPIRKIYIELICVILLTVSL--FAF 376
Query: 338 ARARSYGALVAFCVAFGLSYGMVGALQFEVLMA--AVGAPRFPSALGLVLLVEAAAVLIG 395
A + L++ + FG G +G +L VG + SA G+ + +++ A L G
Sbjct: 377 TFATEFWGLMSCSIFFGFMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYIFIQSIAGLAG 436
Query: 396 PPSAGRLVDVLKNYEIIFYLAGSEVALAGVFMAVATNCCLRCAKAAPSG 444
PP AG LVD K Y FY + +ALA V +A+ C + + SG
Sbjct: 437 PPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKMGLCQHHHSG 485
>gi|18699730 solute carrier family 16, member 10 [Homo sapiens]
Length = 515
Score = 182 bits (461), Expect = 8e-46
Identities = 123/432 (28%), Positives = 199/432 (46%), Gaps = 33/432 (7%)
Query: 6 PRRGEGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSD-----TAWV 60
P PP+GGWGW+V+ A G +G A V F +++ F + D TAWV
Sbjct: 58 PHEPPEPPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVFKTAWV 117
Query: 61 SSIMLAMLYGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTG 120
S+ + M++ P+ S+ FGCR + G + G++ +SF + + LYLT G++
Sbjct: 118 GSLSMGMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGIIFA 177
Query: 121 LGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLL 180
G + +QPSL++LG YF++R L NG+ AGS VF L L + L++ G +L
Sbjct: 178 CGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFYTLRVL 237
Query: 181 GGLLLHCCACGAVMRPPPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREASPRVRPRR 240
+ G RP + + E+ G+G L + + P +
Sbjct: 238 CIFMFVLFLAGFTYRP----------------LATSTKDKESGGSGSSL-FSRKKFSPPK 280
Query: 241 RLLDLAVCTDRAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLSIVGFVDI 300
++ + A+ A+AV+AV L G FVP + L+ + + + + +L +G
Sbjct: 281 KIFNFAIFKVTAYAVWAVGIPLALFGYFVPYVHLMKHVNERFQDEKNKEVVLMCIGVTSG 340
Query: 301 VARPACGALAGLARLRPHVP-----YLFSLALLANGLTDLSSARARSYGALVAFCVAFGL 355
V R G R+ +VP YL L+ GL + +GAL+A C+ GL
Sbjct: 341 VGRLLFG------RIADYVPGVKKVYLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGL 394
Query: 356 SYGMVGALQFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIFYL 415
G ++ + VGA A+G +L + + +GPP AG L D L +Y++ FYL
Sbjct: 395 FDGCFISIMAPIAFELVGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYL 454
Query: 416 AGSEVALAGVFM 427
AG + G +
Sbjct: 455 AGVPPLIGGAVL 466
>gi|41327156 solute carrier family 16 (monocarboxylic acid
transporters), member 14 [Homo sapiens]
Length = 510
Score = 166 bits (420), Expect = 5e-41
Identities = 122/475 (25%), Positives = 201/475 (42%), Gaps = 60/475 (12%)
Query: 14 DGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAWVSSIMLAMLYGTGP 73
DGGW W+++ + F V G A+ V + +F TAWVSS+ + + GP
Sbjct: 29 DGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRGLTAWVSSLSMGITLIVGP 88
Query: 74 VSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGLALNFQPSLIM 133
+ + GCR + GGL+ S G +L+++A + L++T GV GLG + + P+++M
Sbjct: 89 FIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVHYLFITFGVAAGLGSGMAYLPAVVM 148
Query: 134 LGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLLGGLLLHCCACGAV 193
+G YF++RR LA GL+ G+ ++ L + L +GWR L+ G + L+ C CGA+
Sbjct: 149 VGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMLIQGAVSLNLCVCGAL 208
Query: 194 MRP-PPGPGPR----------PRRDSAGDRAGDAPGEAEADGAG---------LQLREAS 233
MRP PG P P + ++ G E G LQ +E
Sbjct: 209 MRPLSPGKNPNDPGEKDVRGLPAHSTESVKSTGQQGRTEEKDGGLGNEETLCDLQAQECP 268
Query: 234 PRVRPRRRLLDLAVC----------------------------TDRAFAVYAVTKFLMAL 265
+ R+ + L + T+R F +
Sbjct: 269 DQAGHRKNMCALRILKTVSWLTMRVRKGFEDWYSGYFGTASLFTNRMFVAFIFWALFAYS 328
Query: 266 GLFVPAILLVNYAKDAGVPDTDAAF-LLSIVGFVDIVARPACGALAGLARLRPHVPYLFS 324
+P I L + + + F L SI+ V I + G +A L + +++
Sbjct: 329 SFVIPFIHLPEIVNLYNLSEQNDVFPLTSIIAIVHIFGKVILGVIADLPCIS-----VWN 383
Query: 325 LALLANGLTDLS---SARARSYGALVAFCVAFGLSYGMVGALQFEVLMAAVGAPRFPSAL 381
+ LLAN LS +Y L C G S G +L V VG +A
Sbjct: 384 VFLLANFTLVLSIFILPLMHTYAGLAVICALIGFSSGYF-SLMPVVTEDLVGIEHLANAY 442
Query: 382 GLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIFYLAGSEVALAGVFMAVATNCCLR 436
G+++ + L+GPP AG + D+ + Y+ FY+ G + +F+ + C+R
Sbjct: 443 GIIICANGISALLGPPFAGWIYDITQKYDFSFYICGLLYMIGILFLLIQP--CIR 495
>gi|5730045 solute carrier family 16, member 2 [Homo sapiens]
Length = 613
Score = 163 bits (413), Expect = 3e-40
Identities = 119/432 (27%), Positives = 190/432 (43%), Gaps = 33/432 (7%)
Query: 5 GPRRGEGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDT----AWV 60
G RG PP+GG+GWVV+ A G +G +V + + L+ + AWV
Sbjct: 161 GTARGFQPPEGGFGWVVVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNRQVEFQAAWV 220
Query: 61 SSIMLAMLYGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTG 120
++ + M++ P+ SI R GCR AG +A G+ +SF + L Y T G+L G
Sbjct: 221 GALAMGMIFFCSPIVSIFTDRLGCRITATAGAAVAFIGLHTSSFTSSLSLRYFTYGILFG 280
Query: 121 LGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLL 180
G + FQPSL++LG YF+RR LANG+ +AGS +F + L + L ++ F +L
Sbjct: 281 CGCSFAFQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIRMLGDKIKLAQTFQVL 340
Query: 181 GGLLLHCCACGAVMRPPPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREASPR-VRPR 239
+ RP P + G +R R +
Sbjct: 341 STFMFVLMLLSLTYRP-----LLPSSQDTPSKRG--------------VRTLHQRFLAQL 381
Query: 240 RRLLDLAVCTDRAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLSIVGFVD 299
R+ ++ V R + ++A ALG FVP + L+ Y ++ + LL +G
Sbjct: 382 RKYFNMRVFRQRTYRIWAFGIAAAALGYFVPYVHLMKYVEEEFSEIKETWVLLVCIGATS 441
Query: 300 IVARPACG----ALAGLARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAFGL 355
+ R G ++ GL ++ YL L+ L GL + R +G L+ C+ GL
Sbjct: 442 GLGRLVSGHISDSIPGLKKI-----YLQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGL 496
Query: 356 SYGMVGALQFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIFYL 415
G + + VG + A+G +L + A ++ GPP AG L + +Y + FY
Sbjct: 497 CDGFFITIMAPIAFELVGPMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFGDYHVAFYF 556
Query: 416 AGSEVALAGVFM 427
AG + V +
Sbjct: 557 AGVPPIIGAVIL 568
>gi|4759114 solute carrier family 16, member 4 [Homo sapiens]
Length = 487
Score = 149 bits (375), Expect = 8e-36
Identities = 111/459 (24%), Positives = 198/459 (43%), Gaps = 50/459 (10%)
Query: 14 DGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAWVSSIMLAMLYGTGP 73
DGGWGW+++ F+V F G K ++FF +F+ W+ SIM ++ + GP
Sbjct: 16 DGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFCAGP 75
Query: 74 VSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGLALNFQPSLIM 133
+ +I+ G + + G + + G +++S+AT + L +T G+L GLG A +Q + ++
Sbjct: 76 LVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVAAVV 135
Query: 134 LGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLLGGLLLHCCACGAV 193
YF++R L+ +A +G + L+P + L++ + W G +L G + L+ +
Sbjct: 136 TTKYFKKRLALSTAIARSGMGLTF-LLAPFTKFLIDLYDWTGALILFGAIALNLVPSSML 194
Query: 194 MRP-------------------PPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREASP 234
+RP GP + ++ AGL + +
Sbjct: 195 LRPIHIKSENNSGIKDKGSSLSAHGPEAHATETHCHETEESTIKDSTTQKAGLPSKNLTV 254
Query: 235 RVRP---------RRRLL-------------------DLAVCTDRAFAVYAVTKFLMALG 266
R RLL D+++ + F ++ + L L
Sbjct: 255 SQNQSEEFYNGPNRNRLLLKSDEESDKVISWSCKQLFDISLFRNPFFYIFTWSFLLSQLA 314
Query: 267 LFVPAILLVNYAKDAGVPDTDAAFLLSIVGFVDIVARPACGALAGLARLRPHVPYLFSLA 326
F+P LV AK G+ DA++L+S+ G ++ V++ G +A ++ + +
Sbjct: 315 YFIPTFHLVARAKTLGIDIMDASYLVSVAGILETVSQIISGWVADQNWIKKY--HYHKSY 372
Query: 327 LLANGLTDLSSARARSYGALVAFCVAFGLSYGMVGALQFEVLMAAVGAPRFPSALGLVLL 386
L+ G+T+L + A ++ L+ + + F + G AL VL+ LGL
Sbjct: 373 LILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLALILPVLVDLCRNSTVNRFLGLASF 432
Query: 387 VEAAAVLIGPPSAGRLVDVLKNYEIIFYLAGSEVALAGV 425
AVL GPP AG L D + Y FY +G L+ V
Sbjct: 433 FAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLLSSV 471
>gi|34916028 solute carrier family 16 (monocarboxylic acid
transporters), member 9 [Homo sapiens]
Length = 509
Score = 135 bits (339), Expect = 1e-31
Identities = 70/184 (38%), Positives = 105/184 (57%)
Query: 13 PDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAWVSSIMLAMLYGTG 72
PDGGWGWV++ F+ YG P AV V + + F G TAWV S+ +
Sbjct: 7 PDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLLAS 66
Query: 73 PVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGLALNFQPSLI 132
PV S+ V+ FG RPV + G + + G++L+SFA + L+ + G++ GLG L + ++
Sbjct: 67 PVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTATVT 126
Query: 133 MLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLLGGLLLHCCACGA 192
+ YF+ RR LA GL + GS V L + L + L+E +G G L++G L L+ ACG+
Sbjct: 127 ITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILACGS 186
Query: 193 VMRP 196
+MRP
Sbjct: 187 LMRP 190
Score = 64.3 bits (155), Expect = 2e-10
Identities = 51/205 (24%), Positives = 89/205 (43%), Gaps = 9/205 (4%)
Query: 245 LAVCTDRAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAF-LLSIVGFVDIVAR 303
+A+ ++ F+ + L +G F P++L+ + A+ + V + + L+SI+G + V +
Sbjct: 298 VALFKNKVFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGK 357
Query: 304 PACGALAGLARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAFGLSYGMVGAL 363
G LA + + YL+ L+ GL + A+SY L G G
Sbjct: 358 LLLGILADFKWI--NTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNWSIF 415
Query: 364 QFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIFYLAGSEVALA 423
+ V VG + A G+++ +GPP G D + Y+I FY +G V L
Sbjct: 416 PY-VTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLG 474
Query: 424 GVFMAVAT-----NCCLRCAKAAPS 443
G + +A C + K AP+
Sbjct: 475 GFILLLAALPSWDTCNKQLPKPAPT 499
>gi|154350196 vesicular nucleotide transporter SLC17A9 [Homo
sapiens]
Length = 436
Score = 36.2 bits (82), Expect = 0.072
Identities = 45/187 (24%), Positives = 70/187 (37%), Gaps = 11/187 (5%)
Query: 5 GPRRGEGPPDGGW-GWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAWVSSI 63
G + P W G ++LG C + Y ++ + ++ +DF + V S
Sbjct: 14 GDTQWSRPECQAWTGTLLLGTCLL-----YCARSSMPICTVSMSQDFGWNKKEAGIVLSS 68
Query: 64 MLAMLYGTGPVSSILVTRFGCRPVML----AGGLLASAGMILASFATRLLELYLTAGVLT 119
T V L R G V+L A G + + +LA ++ L + +L
Sbjct: 69 FFWGYCLTQVVGGHLGDRIGGEKVILLSASAWGSITAVTPLLAHLSSAHLAFMTFSRILM 128
Query: 120 GLGLALNFQPSLIMLGLYF-ERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFL 178
GL + F +L E R + AGS +G LLE +GW+ F
Sbjct: 129 GLLQGVYFPALTSLLSQKVRESERAFTYSIVGAGSQFGTLLTGAVGSLLLEWYGWQSIFY 188
Query: 179 LLGGLLL 185
GGL L
Sbjct: 189 FSGGLTL 195
>gi|20336188 paired basic amino acid cleaving system 4 isoform e
preproprotein [Homo sapiens]
Length = 623
Score = 35.0 bits (79), Expect = 0.16
Identities = 27/56 (48%), Positives = 30/56 (53%), Gaps = 5/56 (8%)
Query: 195 RPPPGPGPR--PRRDSAGDRAGDAPGEAEADGA-GLQLREASPRVRPRRRLLDLAV 247
R PP PGPR PR +A D A A G A GA G R +P RP R LL LA+
Sbjct: 4 RAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAP--RPWRWLLLLAL 57
>gi|20336186 paired basic amino acid cleaving system 4 isoform c
preproprotein [Homo sapiens]
Length = 487
Score = 35.0 bits (79), Expect = 0.16
Identities = 27/56 (48%), Positives = 30/56 (53%), Gaps = 5/56 (8%)
Query: 195 RPPPGPGPR--PRRDSAGDRAGDAPGEAEADGA-GLQLREASPRVRPRRRLLDLAV 247
R PP PGPR PR +A D A A G A GA G R +P RP R LL LA+
Sbjct: 4 RAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAP--RPWRWLLLLAL 57
>gi|27894285 paired basic amino acid cleaving system 4 isoform f
preproprotein [Homo sapiens]
Length = 664
Score = 35.0 bits (79), Expect = 0.16
Identities = 27/56 (48%), Positives = 30/56 (53%), Gaps = 5/56 (8%)
Query: 195 RPPPGPGPR--PRRDSAGDRAGDAPGEAEADGA-GLQLREASPRVRPRRRLLDLAV 247
R PP PGPR PR +A D A A G A GA G R +P RP R LL LA+
Sbjct: 4 RAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAP--RPWRWLLLLAL 57
>gi|20336190 paired basic amino acid cleaving system 4 isoform d
preproprotein [Homo sapiens]
Length = 652
Score = 35.0 bits (79), Expect = 0.16
Identities = 27/56 (48%), Positives = 30/56 (53%), Gaps = 5/56 (8%)
Query: 195 RPPPGPGPR--PRRDSAGDRAGDAPGEAEADGA-GLQLREASPRVRPRRRLLDLAV 247
R PP PGPR PR +A D A A G A GA G R +P RP R LL LA+
Sbjct: 4 RAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAP--RPWRWLLLLAL 57
>gi|20336184 paired basic amino acid cleaving system 4 isoform h
preproprotein [Homo sapiens]
Length = 962
Score = 35.0 bits (79), Expect = 0.16
Identities = 27/56 (48%), Positives = 30/56 (53%), Gaps = 5/56 (8%)
Query: 195 RPPPGPGPR--PRRDSAGDRAGDAPGEAEADGA-GLQLREASPRVRPRRRLLDLAV 247
R PP PGPR PR +A D A A G A GA G R +P RP R LL LA+
Sbjct: 4 RAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAP--RPWRWLLLLAL 57
>gi|20336182 paired basic amino acid cleaving system 4 isoform g
preproprotein [Homo sapiens]
Length = 975
Score = 35.0 bits (79), Expect = 0.16
Identities = 27/56 (48%), Positives = 30/56 (53%), Gaps = 5/56 (8%)
Query: 195 RPPPGPGPR--PRRDSAGDRAGDAPGEAEADGA-GLQLREASPRVRPRRRLLDLAV 247
R PP PGPR PR +A D A A G A GA G R +P RP R LL LA+
Sbjct: 4 RAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAP--RPWRWLLLLAL 57
>gi|4505577 paired basic amino acid cleaving system 4 isoform a
preproprotein [Homo sapiens]
Length = 969
Score = 35.0 bits (79), Expect = 0.16
Identities = 27/56 (48%), Positives = 30/56 (53%), Gaps = 5/56 (8%)
Query: 195 RPPPGPGPR--PRRDSAGDRAGDAPGEAEADGA-GLQLREASPRVRPRRRLLDLAV 247
R PP PGPR PR +A D A A G A GA G R +P RP R LL LA+
Sbjct: 4 RAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAP--RPWRWLLLLAL 57
>gi|20336180 paired basic amino acid cleaving system 4 isoform b
preproprotein [Homo sapiens]
Length = 956
Score = 35.0 bits (79), Expect = 0.16
Identities = 27/56 (48%), Positives = 30/56 (53%), Gaps = 5/56 (8%)
Query: 195 RPPPGPGPR--PRRDSAGDRAGDAPGEAEADGA-GLQLREASPRVRPRRRLLDLAV 247
R PP PGPR PR +A D A A G A GA G R +P RP R LL LA+
Sbjct: 4 RAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAP--RPWRWLLLLAL 57
>gi|4885441 solute carrier family 17 (sodium phosphate), member 4
[Homo sapiens]
Length = 497
Score = 33.5 bits (75), Expect = 0.46
Identities = 40/163 (24%), Positives = 68/163 (41%), Gaps = 23/163 (14%)
Query: 42 FFRALMRDFDA---GYSDTAWVSSIMLAML-YGT--GPVSSILVTR-FGCRPVMLAGGLL 94
++ +++F A Y + + I+L+ L YG+ P+ S V FG + V+
Sbjct: 88 YWNETLKEFKAMAPAYDWSPEIQGIILSSLNYGSFLAPIPSGYVAGIFGAKYVV------ 141
Query: 95 ASAGMILASFATRLLELYLTAGV--LTGLGLALNFQPSLIMLGLYF-------ERRRPLA 145
AG+ ++SF T + L AGV L L + +++ G Y R
Sbjct: 142 -GAGLFISSFLTLFIPLAANAGVALLIVLRIVQGIAQVMVLTGQYSIWVKWAPPLERSQL 200
Query: 146 NGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLLGGLLLHCC 188
+A +GS + + G L + GW F + GG+ CC
Sbjct: 201 TTIAGSGSMLGSFIVLLAGGLLCQTIGWPYVFYIFGGIGCACC 243
>gi|42476325 solute carrier family 18 (vesicular monoamine), member
2 [Homo sapiens]
Length = 514
Score = 33.1 bits (74), Expect = 0.61
Identities = 31/117 (26%), Positives = 49/117 (41%), Gaps = 3/117 (2%)
Query: 71 TGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGLALNFQPS 130
T P +L R G + AG + I+ +F++ L L A L G+G + +
Sbjct: 145 TNPFIGLLTNRIGYPIPIFAGFCIMFVSTIMFAFSSSYAFL-LIARSLQGIGSSCSSVAG 203
Query: 131 LIMLGLYF--ERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLLGGLLL 185
+ ML + + R G+A G + + P G L E G FL+L L+L
Sbjct: 204 MGMLASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVLYEFVGKTAPFLVLAALVL 260
>gi|215272392 solute carrier family 18 (vesicular monoamine), member
1 isoform c [Homo sapiens]
Length = 472
Score = 33.1 bits (74), Expect = 0.61
Identities = 31/115 (26%), Positives = 48/115 (41%), Gaps = 3/115 (2%)
Query: 73 PVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGLALNFQPSLI 132
P L R G M AG ++ ++ +F+ L++ A L G+G + + L
Sbjct: 155 PFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFV-ARTLQGIGSSFSSVAGLG 213
Query: 133 MLGLYF--ERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLLGGLLL 185
ML + + R A G A G + L +P G + E G FL+L L L
Sbjct: 214 MLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLILAFLAL 268
>gi|215272390 solute carrier family 18 (vesicular monoamine), member
1 isoform b [Homo sapiens]
Length = 493
Score = 33.1 bits (74), Expect = 0.61
Identities = 31/115 (26%), Positives = 48/115 (41%), Gaps = 3/115 (2%)
Query: 73 PVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGLALNFQPSLI 132
P L R G M AG ++ ++ +F+ L++ A L G+G + + L
Sbjct: 155 PFVGPLTNRIGYHIPMFAGFVIMFLSTVMFAFSGTYTLLFV-ARTLQGIGSSFSSVAGLG 213
Query: 133 MLGLYF--ERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLLGGLLL 185
ML + + R A G A G + L +P G + E G FL+L L L
Sbjct: 214 MLASVYTDDHERGRAMGTALGGLALGLLVGAPFGSVMYEFVGKSAPFLILAFLAL 268
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.141 0.428
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,664,841
Number of Sequences: 37866
Number of extensions: 1044145
Number of successful extensions: 5497
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 65
Number of HSP's that attempted gapping in prelim test: 5325
Number of HSP's gapped (non-prelim): 201
length of query: 504
length of database: 18,247,518
effective HSP length: 107
effective length of query: 397
effective length of database: 14,195,856
effective search space: 5635754832
effective search space used: 5635754832
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.