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Search of human proteins with 114155158
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|114155158 Ras association (RalGDS/AF-6) domain family
(N-terminal) member 9 [Homo sapiens]
(435 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|114155158 Ras association (RalGDS/AF-6) domain family (N-term... 869 0.0
gi|122937480 Ras association (RalGDS/AF-6) domain family (N-term... 238 6e-63
gi|23503243 Ras association (RalGDS/AF-6) domain family (N-termi... 81 2e-15
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 49 9e-06
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 49 9e-06
gi|4503179 oral-facial-digital syndrome 1 [Homo sapiens] 45 1e-04
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 44 3e-04
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 44 3e-04
gi|45439327 periplakin [Homo sapiens] 44 4e-04
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 43 6e-04
gi|109255234 centrosomal protein 290kDa [Homo sapiens] 42 8e-04
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 42 0.001
gi|71061468 centromere protein E [Homo sapiens] 42 0.001
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 41 0.002
gi|119943086 Tax1 (human T-cell leukemia virus type I) binding p... 40 0.003
gi|21361682 Tax1 (human T-cell leukemia virus type I) binding pr... 40 0.003
gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens] 40 0.003
gi|55770834 centromere protein F [Homo sapiens] 40 0.004
gi|21735569 claspin [Homo sapiens] 40 0.005
gi|7705415 hook homolog 1 [Homo sapiens] 40 0.005
gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens] 40 0.005
gi|5031741 DnaJ subfamily A member 2 [Homo sapiens] 39 0.007
gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 39 0.007
gi|64085252 hypothetical protein LOC145508 [Homo sapiens] 39 0.009
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 39 0.012
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 39 0.012
gi|126362969 Nck-associated protein 5 isoform 2 [Homo sapiens] 38 0.016
gi|126362967 Nck-associated protein 5 isoform 1 [Homo sapiens] 38 0.016
gi|41872583 Rho-associated, coiled-coil containing protein kinas... 38 0.021
gi|31982906 cingulin-like 1 [Homo sapiens] 38 0.021
>gi|114155158 Ras association (RalGDS/AF-6) domain family
(N-terminal) member 9 [Homo sapiens]
Length = 435
Score = 869 bits (2245), Expect = 0.0
Identities = 435/435 (100%), Positives = 435/435 (100%)
Query: 1 MAPFGRNLLKTRHKNRSPTKDMDSEEKEIVVWVCQEEKLVCGLTKRTTSADVIQALLEEH 60
MAPFGRNLLKTRHKNRSPTKDMDSEEKEIVVWVCQEEKLVCGLTKRTTSADVIQALLEEH
Sbjct: 1 MAPFGRNLLKTRHKNRSPTKDMDSEEKEIVVWVCQEEKLVCGLTKRTTSADVIQALLEEH 60
Query: 61 EATFGEKRFLLGKPSDYCIIEKWRGSERVLPPLTRILKLWKAWGDEQPNMQFVLVKADAF 120
EATFGEKRFLLGKPSDYCIIEKWRGSERVLPPLTRILKLWKAWGDEQPNMQFVLVKADAF
Sbjct: 61 EATFGEKRFLLGKPSDYCIIEKWRGSERVLPPLTRILKLWKAWGDEQPNMQFVLVKADAF 120
Query: 121 LPVPLWRTAEAKLVQNTEKLWELSPANYMKTLPPDKQKRIVRKTFRKLAKIKQDTVSHDR 180
LPVPLWRTAEAKLVQNTEKLWELSPANYMKTLPPDKQKRIVRKTFRKLAKIKQDTVSHDR
Sbjct: 121 LPVPLWRTAEAKLVQNTEKLWELSPANYMKTLPPDKQKRIVRKTFRKLAKIKQDTVSHDR 180
Query: 181 DNMETLVHLIISQDHTIHQQVKRMKELDLEIEKCEAKFHLDRVENDGENYVQDAYLMPSF 240
DNMETLVHLIISQDHTIHQQVKRMKELDLEIEKCEAKFHLDRVENDGENYVQDAYLMPSF
Sbjct: 181 DNMETLVHLIISQDHTIHQQVKRMKELDLEIEKCEAKFHLDRVENDGENYVQDAYLMPSF 240
Query: 241 SEVEQNLDLQYEENQTLEDLSESDGIEQLEERLKYYRILIDKLSAEIEKEVKSVCIDINE 300
SEVEQNLDLQYEENQTLEDLSESDGIEQLEERLKYYRILIDKLSAEIEKEVKSVCIDINE
Sbjct: 241 SEVEQNLDLQYEENQTLEDLSESDGIEQLEERLKYYRILIDKLSAEIEKEVKSVCIDINE 300
Query: 301 DAEGEAASELESSNLESVKCDLEKSMKAGLKIHSHLSGIQKEIKYSDSLLQMKAKEYELL 360
DAEGEAASELESSNLESVKCDLEKSMKAGLKIHSHLSGIQKEIKYSDSLLQMKAKEYELL
Sbjct: 301 DAEGEAASELESSNLESVKCDLEKSMKAGLKIHSHLSGIQKEIKYSDSLLQMKAKEYELL 360
Query: 361 AKEFNSLHISNKDGCQLKENRAKESEVPSSNGEIPPFTQRVFSNYTNDTDSDTGISSNHS 420
AKEFNSLHISNKDGCQLKENRAKESEVPSSNGEIPPFTQRVFSNYTNDTDSDTGISSNHS
Sbjct: 361 AKEFNSLHISNKDGCQLKENRAKESEVPSSNGEIPPFTQRVFSNYTNDTDSDTGISSNHS 420
Query: 421 QDSETTVGDVVLLST 435
QDSETTVGDVVLLST
Sbjct: 421 QDSETTVGDVVLLST 435
>gi|122937480 Ras association (RalGDS/AF-6) domain family
(N-terminal) member 10 [Homo sapiens]
Length = 615
Score = 238 bits (608), Expect = 6e-63
Identities = 171/500 (34%), Positives = 257/500 (51%), Gaps = 97/500 (19%)
Query: 22 MDSEEKEIVVWVCQEEKLVCGLTKRTTSADVIQALLEEHEATFGEKR------------- 68
MD EK+I VW+CQEEKLV GL++RTT +DV++ LLE+ +R
Sbjct: 109 MDPSEKKISVWICQEEKLVSGLSRRTTCSDVVRVLLEDGCRRRRRQRRSRRLGSAGDPHG 168
Query: 69 ----------------------FLLGKPSDYCIIEKWRGSERVLPPLTRILKLWKAWGDE 106
L G P YCI+EKWRG ER+LP TRIL+LW AWG+E
Sbjct: 169 PGELPEPPNEDDEDDDEALPQGMLCGPPQCYCIVEKWRGFERILPNKTRILRLWAAWGEE 228
Query: 107 QPNMQFVLVKADAFLPVPLWRTAEAKLVQNTEKLWEL--SPANYMKTLPPDKQKRIVRKT 164
Q N++FVLV+++A LP R+AEA++V + E+ +PA + +KQ+R+VRK
Sbjct: 229 QENVRFVLVRSEASLPNAGPRSAEARVVLSRERPCPARGAPARPSLAMTQEKQRRVVRKA 288
Query: 165 FRKLAKI----KQDTVS-------------------HDR---DNMETLVHLIISQDHTIH 198
FRKLAK+ +Q T S H+ + METLVHL++SQDHTI
Sbjct: 289 FRKLAKLNRRRQQQTPSSCSSTSSSTASSCSSSPRTHESASVERMETLVHLVLSQDHTIR 348
Query: 199 QQVKRMKELDLEIEKCEAKFHLDRVENDGENYVQDAYLMPSFSEVE--------QNLDLQ 250
QQV+R+ ELD EI+ EAK HLDR+ G NYVQD YL+ + E++ + + +
Sbjct: 349 QQVQRLHELDREIDHYEAKVHLDRMRRHGVNYVQDTYLVGAGIELDGSRPGEEPEEVAAE 408
Query: 251 YEE------------NQTLEDLS-ESDGIEQLEERLKYYRILIDKLSAEIEKEVKSVCID 297
EE LE+L+ D + +L+E+ L+++LSAEI++E+ +
Sbjct: 409 AEEAAAAPPLAGEAQAAALEELARRCDDLLRLQEQRVQQEELLERLSAEIQEELNQRWMR 468
Query: 298 INEDAEGEAASELESS---------NLESVKCDLEKSMKAGLKIHSHLSGIQKEIKYSDS 348
++ LE E V+ L S+ GL++++ L ++ ++ YS
Sbjct: 469 RRQEELAAREEPLEPDGGPDGELLLEQERVRTQLSTSLYIGLRLNTDLEAVKSDLDYSQQ 528
Query: 349 LLQMKAKEYELLAKEFNSLHIS-NKDGCQLKENRAKESEVPSSNGEIPPFTQR--VFSNY 405
K +E + L + ++L ++ DG + ++E P + ++ R S
Sbjct: 529 QWDSKKRELQGLLQTLHTLELTVAPDGAPGSGSPSREPG-PQACADMWVDQARGLAKSGP 587
Query: 406 TNDTDSDTGISSNHSQDSET 425
ND DSDTG+SS HSQDS++
Sbjct: 588 GNDEDSDTGLSSMHSQDSDS 607
>gi|23503243 Ras association (RalGDS/AF-6) domain family
(N-terminal) member 8 [Homo sapiens]
Length = 392
Score = 81.3 bits (199), Expect = 2e-15
Identities = 88/403 (21%), Positives = 167/403 (41%), Gaps = 63/403 (15%)
Query: 28 EIVVWVCQEEKLVCGLTKRTTSADVIQALLEEHEATFGEKRFLLGKPSDYCIIEKWRGSE 87
E+ VWV +++VCG+T+ TT +V+ AL + +G+ Y +IEKWR +E
Sbjct: 2 ELKVWVDGVQRIVCGVTEVTTCQEVVIALAQA-----------IGRTGRYTLIEKWRDTE 50
Query: 88 RVLPPLTRILKLWKAWGDEQPNMQFVLVKADAFLPVPLWRTAEAKLVQNTEKLWELSPAN 147
R L P + WG ++Q +L + L + A++ + T L P
Sbjct: 51 RHLAPHENPIISLNKWGQYASDVQLILRRTGPSLSERPTSDSVARIPERTLYRQSLPP-- 108
Query: 148 YMKTLPPDKQKRIVRK-------TFR-------------KLAKIKQDTVSHDRDNMETLV 187
+ L P K I R+ TF K + KQ +++ + + L
Sbjct: 109 -LAKLRPQIDKSIKRREPKRKSLTFTGGAKGLMDIFGKGKETEFKQKVLNNCKTTADELK 167
Query: 188 HLIISQDHTIHQQVKRMKELDLEIEKCEAKFHLDRVE-----------NDGENYVQDAYL 236
LI Q + K+++ ++EI E K++ + E ND E ++ +
Sbjct: 168 KLIRLQTEKLQSIEKQLESNEIEIRFWEQKYNSNLEEEIVRLEQKIKRNDVEIEEEEFW- 226
Query: 237 MPSFSEVEQNLDLQYEENQTLEDLSES--DGIEQLEERLKYYRILIDKLSAEIEKEVKSV 294
E L ++ E + L+D + I + E +LK Y I + + +E E
Sbjct: 227 -------ENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEAEKLQ- 278
Query: 295 CIDINEDAEGEAASELESSNLESVKCDLEKSMKAGLKIHSHLSGIQKEIKYSDSLLQMKA 354
E E + E + VK +++ + L++ + + +++ + + LQ K
Sbjct: 279 ----REVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQATKRLQDKE 334
Query: 355 KEYELLAKEFNSLHIS---NKDGCQLKENRAKESEVPSSNGEI 394
+E E L KE +++ + G ++ A+ E+ +S+ +I
Sbjct: 335 QELEQLTKELRQVNLQQFIQQTGTKVTVLPAEPIEIEASHADI 377
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 48.9 bits (115), Expect = 9e-06
Identities = 53/232 (22%), Positives = 103/232 (44%), Gaps = 24/232 (10%)
Query: 156 KQKRIVRKTFRKLAKIKQDTVSHDRDNMETLVHLIISQDHTIHQQVKRMKELDLEIEKCE 215
KQ +++ + KL ++Q V+ + M ++ + + + Q+ K L+ E+++ +
Sbjct: 691 KQNQLILE-ISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQ 749
Query: 216 AKFHL-DRVENDGENYVQDAYLMPSFSEVEQNLDLQYEENQTLEDLSESDGIEQLEERLK 274
K L ++ + EN +Q+ F+++E + +E +TLED+ + EERL
Sbjct: 750 LKTELLEKQMKEKENDLQE-----KFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLI 804
Query: 275 YYRILIDKLSAEI-EKEV----------KSVCIDINEDAEGEAAS-ELESSNLESVKCDL 322
+ + K + EKE+ K CI +NE+ E + + N E +L
Sbjct: 805 FLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQEL 864
Query: 323 EKSMKAGLKIHSHL--SGIQKEIKYSDSLLQMKAKEYELLAKEFNSLHISNK 372
++ LK+ L S ++E++Y L KA EL + N + K
Sbjct: 865 QEEYACLLKVKDDLEDSKNKQELEYKSKL---KALNEELHLQRINPTTVKMK 913
Score = 32.7 bits (73), Expect = 0.66
Identities = 36/166 (21%), Positives = 69/166 (41%), Gaps = 23/166 (13%)
Query: 164 TFRKLAKIKQDTVSHDRDNMETLVHLIISQDHTIHQQVKRMKELDLEIEKCEAKFHLDRV 223
T L + KQ ++H + E QDH + K+ ++ ++I + K + +
Sbjct: 259 TAADLLQAKQQILTHQQQLEE--------QDHLLEDYQKKKEDFTMQISFLQEKIKVYEM 310
Query: 224 ENDG--ENYVQDAYLMPSFSEVEQNLDLQYEENQTLEDLSESDGIEQLEERLKYYRILID 281
E D EN ++ E N + EE +TLE L+++L L+
Sbjct: 311 EQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLE----------LKDKLTTADKLLG 360
Query: 282 KLSAEI---EKEVKSVCIDINEDAEGEAASELESSNLESVKCDLEK 324
+L +I +E+K++ +++ + E S E L +L+K
Sbjct: 361 ELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQK 406
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 48.9 bits (115), Expect = 9e-06
Identities = 53/232 (22%), Positives = 103/232 (44%), Gaps = 24/232 (10%)
Query: 156 KQKRIVRKTFRKLAKIKQDTVSHDRDNMETLVHLIISQDHTIHQQVKRMKELDLEIEKCE 215
KQ +++ + KL ++Q V+ + M ++ + + + Q+ K L+ E+++ +
Sbjct: 691 KQNQLILE-ISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQ 749
Query: 216 AKFHL-DRVENDGENYVQDAYLMPSFSEVEQNLDLQYEENQTLEDLSESDGIEQLEERLK 274
K L ++ + EN +Q+ F+++E + +E +TLED+ + EERL
Sbjct: 750 LKTELLEKQMKEKENDLQE-----KFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLI 804
Query: 275 YYRILIDKLSAEI-EKEV----------KSVCIDINEDAEGEAAS-ELESSNLESVKCDL 322
+ + K + EKE+ K CI +NE+ E + + N E +L
Sbjct: 805 FLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQEL 864
Query: 323 EKSMKAGLKIHSHL--SGIQKEIKYSDSLLQMKAKEYELLAKEFNSLHISNK 372
++ LK+ L S ++E++Y L KA EL + N + K
Sbjct: 865 QEEYACLLKVKDDLEDSKNKQELEYKSKL---KALNEELHLQRINPTTVKMK 913
Score = 32.7 bits (73), Expect = 0.66
Identities = 36/166 (21%), Positives = 69/166 (41%), Gaps = 23/166 (13%)
Query: 164 TFRKLAKIKQDTVSHDRDNMETLVHLIISQDHTIHQQVKRMKELDLEIEKCEAKFHLDRV 223
T L + KQ ++H + E QDH + K+ ++ ++I + K + +
Sbjct: 259 TAADLLQAKQQILTHQQQLEE--------QDHLLEDYQKKKEDFTMQISFLQEKIKVYEM 310
Query: 224 ENDG--ENYVQDAYLMPSFSEVEQNLDLQYEENQTLEDLSESDGIEQLEERLKYYRILID 281
E D EN ++ E N + EE +TLE L+++L L+
Sbjct: 311 EQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLE----------LKDKLTTADKLLG 360
Query: 282 KLSAEI---EKEVKSVCIDINEDAEGEAASELESSNLESVKCDLEK 324
+L +I +E+K++ +++ + E S E L +L+K
Sbjct: 361 ELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQK 406
>gi|4503179 oral-facial-digital syndrome 1 [Homo sapiens]
Length = 1012
Score = 45.1 bits (105), Expect = 1e-04
Identities = 53/240 (22%), Positives = 103/240 (42%), Gaps = 23/240 (9%)
Query: 176 VSHDRDNMETLVHL------IISQDHTIHQQVKRMKELDLEIEKCEAKFHLDRVENDGEN 229
+ +R N E VHL I S+ ++Q V R+KEL+LE+E +A+ +N N
Sbjct: 369 IEDERKNKEKAVHLQEELIAINSKKEELNQSVNRVKELELELESVKAQSLAITKQNHMLN 428
Query: 230 YVQDAYLMPSFSEVEQNLDLQYEENQTLEDLSESDGI-EQLEERLKYYRILIDKLSAEIE 288
+V++ D + + LE L+++ + +QLEE L+++L+
Sbjct: 429 -----------EKVKEMSDYSLLKEEKLELLAQNKLLKQQLEESRNENLRLLNRLA---- 473
Query: 289 KEVKSVCIDINEDAEGEAASELESSNLESVKCDLEKSMKAGLKIHSHLSGIQKEIKYSDS 348
+ + + E + E A +E ES + L K ++ ++ + L K S
Sbjct: 474 QPAPELAVFQKELRKAEKAIVVEHEEFESCRQALHKQLQDEIEHSAQLKAQILGYKASVK 533
Query: 349 LLQMKAKEYELLAKEFNSLHISNKDGCQLKENRAKESEVPSSNGEIPPFTQRVFSNYTND 408
L + + +L K+ + + N+ C K++ S NG + P + ++ N+
Sbjct: 534 SLTTQVADLKLQLKQTQTA-LENEVYCNPKQSVIDRSVNGLINGNVVPCNGEISGDFLNN 592
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 43.9 bits (102), Expect = 3e-04
Identities = 54/245 (22%), Positives = 109/245 (44%), Gaps = 21/245 (8%)
Query: 155 DKQKRIVRKTFRKLAKIKQDTVSHDRDN---------METLVHLIISQDHTIHQQVKRMK 205
+K +R ++T R+L K+K + +R+N ++T + + +Q++ + Q+ ++
Sbjct: 1028 NKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQ 1087
Query: 206 ELDLEIEKCEAKFHLDRVENDGENYVQDAYLMPSFSEVEQNLDLQYEENQTLEDLSESDG 265
+ +++ + EN ++ S S + QN L +++ +LE+ +ES
Sbjct: 1088 RQTVSLQEQNTTLQTQNAKLQVENSTLNSQ---STSLMNQNAQLLIQQS-SLENENESV- 1142
Query: 266 IEQLEERLKYYRILI---DKLSAEIEKEVKSVCIDINEDAEGEAASELESSNLESVKCDL 322
I++ E+ Y LI +KL E++ I++ ++A + NLE DL
Sbjct: 1143 IKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHK----NLEVEHRDL 1198
Query: 323 EKSMKAGLKIHSHLSGIQKEIKYSDSLLQMKAKEYELLAKEFNSLHISNKDGCQLKENRA 382
E LK L ++K +K + ++ K +E +A E+ L N
Sbjct: 1199 EDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLL 1258
Query: 383 KESEV 387
KE+EV
Sbjct: 1259 KETEV 1263
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 43.9 bits (102), Expect = 3e-04
Identities = 54/245 (22%), Positives = 109/245 (44%), Gaps = 21/245 (8%)
Query: 155 DKQKRIVRKTFRKLAKIKQDTVSHDRDN---------METLVHLIISQDHTIHQQVKRMK 205
+K +R ++T R+L K+K + +R+N ++T + + +Q++ + Q+ ++
Sbjct: 1027 NKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQ 1086
Query: 206 ELDLEIEKCEAKFHLDRVENDGENYVQDAYLMPSFSEVEQNLDLQYEENQTLEDLSESDG 265
+ +++ + EN ++ S S + QN L +++ +LE+ +ES
Sbjct: 1087 RQTVSLQEQNTTLQTQNAKLQVENSTLNSQ---STSLMNQNAQLLIQQS-SLENENESV- 1141
Query: 266 IEQLEERLKYYRILI---DKLSAEIEKEVKSVCIDINEDAEGEAASELESSNLESVKCDL 322
I++ E+ Y LI +KL E++ I++ ++A + NLE DL
Sbjct: 1142 IKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHK----NLEVEHRDL 1197
Query: 323 EKSMKAGLKIHSHLSGIQKEIKYSDSLLQMKAKEYELLAKEFNSLHISNKDGCQLKENRA 382
E LK L ++K +K + ++ K +E +A E+ L N
Sbjct: 1198 EDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLL 1257
Query: 383 KESEV 387
KE+EV
Sbjct: 1258 KETEV 1262
>gi|45439327 periplakin [Homo sapiens]
Length = 1756
Score = 43.5 bits (101), Expect = 4e-04
Identities = 38/178 (21%), Positives = 76/178 (42%), Gaps = 25/178 (14%)
Query: 179 DRDNMETLVHLIISQDHTIHQQVKRMKELDLEIEKCEAKFHLDRVENDGENYVQDAYLMP 238
D + E VH + + + + QQV+R + + FH ++ +Q +P
Sbjct: 696 DLERQEAEVHKLGQRFNNLRQQVERRAQSLQSAKAAYEHFHRGH-----DHVLQFLVSIP 750
Query: 239 SFSEVEQNLDLQYEENQTLEDLSESDGIEQLEERLKYYRILIDKLSAEIEKEVKSVCIDI 298
S+ E+D + Q+E +LK + L+D++++ E+EV+ +C +
Sbjct: 751 SYEP------------------QETDSLSQMETKLKNQKNLLDEIASR-EQEVQKICANS 791
Query: 299 NEDAEGEAASELESSNLESVKCDLEKSMKAGLKIHSHLSGIQKEIKYSDSLLQMKAKE 356
+ + ELE+ L S+ DLE + + + L ++K ++ L K E
Sbjct: 792 QQYQQAVKDYELEAEKLRSL-LDLENGRSSHVSKRARLQSPATKVKEEEAALAAKFTE 848
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 42.7 bits (99), Expect = 6e-04
Identities = 57/235 (24%), Positives = 104/235 (44%), Gaps = 36/235 (15%)
Query: 171 IKQDTVSHDRDNMETLVHLIISQDHTIHQQVKRMKELDLEIEKCEAKFHLDRVENDGENY 230
IK+ VS R + L I + + ++ K +KE +E EA + R E + +
Sbjct: 740 IKEHEVSIQRTE-KALKDQINQLELLLKERDKHLKEHQAHVENLEAD--IKRSEGELQQA 796
Query: 231 VQDAYLMPSFSEVEQNLDLQYEENQTLEDLSESDGIEQLEERL---KYYRILIDKLSAEI 287
+ S+ YEE + QL+++L + RIL+ K AE+
Sbjct: 797 SAKLDVFQSYQSATHEQTKAYEEQ-----------LAQLQQKLLDLETERILLTKQVAEV 845
Query: 288 EKEVKSVCIDINEDAEGEAASELESSNLESVKCDLEKSMKAGLKIH-SHLSGIQKE---- 342
E + K VC ++ DA +L LE ++E+ +K+ +++ S L KE
Sbjct: 846 EAQKKDVCTEL--DAHKIQVQDL-MQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQT 902
Query: 343 ----IKYSDSLLQMK---AKEYELLAKEF----NSLHISNKDGCQLKENRAKESE 386
++ + +LQM+ KE E+L ++ +S+HI N++ +N+ K+ E
Sbjct: 903 KQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKME 957
Score = 37.7 bits (86), Expect = 0.021
Identities = 71/350 (20%), Positives = 152/350 (43%), Gaps = 61/350 (17%)
Query: 123 VPLWRTAEAKLVQNTEKLWELSPANYMKTLPPDKQKRIVRKTFRKLAKIKQDT------- 175
V + + + + + +KL E A + L Q R + F++ K+ +
Sbjct: 467 VDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTR--EREFQEQMKVALEKSQSEYLK 524
Query: 176 VSHDRDNMETLV--HLIISQDHTIHQQVKRMKELDLEIEK-----CEAKFHLDRVENDGE 228
+S +++ E+L L + + + + ++++L E E E + L++ + +
Sbjct: 525 ISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENK 584
Query: 229 NYVQD--AYLMPSFSEVEQNLDLQYEENQT-LEDLS-ESDGI--EQLEERLKYYRILIDK 282
N +D +L ++ + + + E+++T LE L + D + E+L+ + Y+ ++K
Sbjct: 585 NQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEK 644
Query: 283 LSAEIEKEVKSVCID--INEDAEGEAASE-------LESSNLESVKCDLEKSMKAGLKIH 333
L + E+E +++ D I A E +E ++ + LES+ +L + +KA K+
Sbjct: 645 LREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLE 704
Query: 334 SHLSGIQKEIKYSDSLLQMK---------------AKEYEL--------LAKEFNSLHIS 370
LS ++ + L+ K KE+E+ L + N L +
Sbjct: 705 EELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELL 764
Query: 371 NKD-GCQLKENRAK----ESEVPSSNGEIPPFTQR--VFSNYTNDTDSDT 413
K+ LKE++A E+++ S GE+ + + VF +Y + T T
Sbjct: 765 LKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQT 814
Score = 32.0 bits (71), Expect = 1.1
Identities = 84/412 (20%), Positives = 166/412 (40%), Gaps = 75/412 (18%)
Query: 9 LKTRHKNRSPTKDMDSEEKEIVVWVCQEEKLVCGLTKRTTSA--DVIQALLEEHEATFGE 66
L+ +K + TK + E++ +++ + + +K + + SA D I L EE+E
Sbjct: 892 LEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYET---- 947
Query: 67 KRFLLGKPSDYCIIEKWRGSERVLPPLTRILKLWKAWGDEQPNMQFVLVKADAFLPVPLW 126
K++ E+ + + + K + Q ++ L+ +A L L
Sbjct: 948 ---------------KFKNQEKKMEKVKQKAK------EMQETLKKKLLDQEAKLKKELE 986
Query: 127 RTA---EAKLVQNTEKLWELSPANYMKTLPPDKQKRIVRKTFRKLAKIKQDTVSHDRDNM 183
TA K Q K+ E++ AN + R + +I+ T H R+
Sbjct: 987 NTALELSQKEKQFNAKMLEMAQANSAGI-----SDAVSRLETNQKEQIESLTEVHRRE-- 1039
Query: 184 ETLVHLIISQDHTIHQQVKRMKEL--------DLEIEKCEAKFHLDRVENDGENYVQDAY 235
L +I + ++QQ + ++E+ + E+ + + K L E + N + +
Sbjct: 1040 --LNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNK-EITW 1096
Query: 236 LMPSFSEVEQNLDLQYEENQTLEDLSESDGIEQLEERLKYYRILIDKLSAEIEKEVKS-- 293
L V+Q+ L + Q + + + + Q E +LK + ++KL ++ K +K
Sbjct: 1097 LKEE--GVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAH---LEKLEVDLNKSLKENT 1151
Query: 294 ------VCIDINEDAEGEAASELESS------NLESVKCDLEKSMKA------GLKIHSH 335
V + + + + SEL S +S+K EKS K+ K S
Sbjct: 1152 FLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSE 1211
Query: 336 LSGIQKEI--KYSDSLLQMKAKEYELLAKEFNSLHISNKDGCQLKENRAKES 385
IQ +I K +++LL+ K E ++ + +S CQ + + KE+
Sbjct: 1212 ELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEA 1263
>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
Length = 2479
Score = 42.4 bits (98), Expect = 8e-04
Identities = 52/210 (24%), Positives = 88/210 (41%), Gaps = 10/210 (4%)
Query: 190 IISQDHTIHQQVKRMKELDLEIEKCEAKFHLDRVEND---GENYVQDAYLMPSFSEVEQN 246
I S DH +Q + + L L E E KF L++ D +N V+D M F + E+
Sbjct: 2049 IESDDHCQREQELQKENLKLSSENIELKFQLEQANKDLPRLKNQVRDLKEMCEFLKKEK- 2107
Query: 247 LDLQYEENQTLEDLSESDGIEQLEERLKYYRILIDKLSAEIEKEVKSVCIDINED-AEGE 305
++Q + I +LE+ + + +++K+ E E+ K+ I +E A E
Sbjct: 2108 AEVQRKLGHVRGSGRSGKTIPELEKTIGLMKKVVEKVQRENEQLKKASGILTSEKMANIE 2167
Query: 306 AASELESSNLESVKCDLEKSMKAGLKIHSHLSGIQKEIKYSDSLLQMKAKEYELLAK--- 362
+E + LE +K L + + S G +K I ++ L + KE + K
Sbjct: 2168 QENEKLKAELEKLKAHLGHQL--SMHYESKTKGTEKIIAENERLRKELKKETDAAEKLRI 2225
Query: 363 EFNSLHISNKDGCQLKENRAKESEVPSSNG 392
N+L I N+ E K + S G
Sbjct: 2226 AKNNLEILNEKMTVQLEETGKRLQFAESRG 2255
Score = 36.6 bits (83), Expect = 0.046
Identities = 54/304 (17%), Positives = 124/304 (40%), Gaps = 58/304 (19%)
Query: 132 KLVQNTEKLWELSPANYMKTLPPDKQKRIVRKTFRKLAKIKQDTVSHDRDNMETLVHLII 191
+L+Q +++ L+ AN + + ++ + ++ +++ K+ + + + M+ +VH
Sbjct: 214 ELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKM-----TDEYNRMKAIVH--- 265
Query: 192 SQDHTIHQQVKRMKELDLEIEKCEAKFHLDRVEND--------------------GENYV 231
D+ I Q K L++++ E+D + +
Sbjct: 266 QTDNVIDQLKKENDHYQLQVQELTDLLKSKNEEDDPIMVAVNAKVEEWKLILSSKDDEII 325
Query: 232 QDAYLMPSFSEVEQNLDLQYEENQTL---EDLSESDG-IEQLEERLKYYRILIDK----- 282
+ ++ + E +N L +++ + + + E D I+ L E+++ Y ++K
Sbjct: 326 EYQQMLHNLREKLKNAQLDADKSNVMALQQGIQERDSQIKMLTEQVEQYTKEMEKNTCII 385
Query: 283 ---------------LSAEIEKEVKSVCIDINEDA-EGEAASELESSNLESVKCDLEKSM 326
LS + +++S + E E E +EL ++ +L +++
Sbjct: 386 EDLKNELQRNKGASTLSQQTHMKIQSTLDILKEKTKEAERTAELAEADAREKDKELVEAL 445
Query: 327 KAGLKIHSHLSGIQK---EIKYSDSLLQMKAKEYELLAKEFNSLHISNKDGCQLKENRAK 383
K S + G++ EIK + ++++ +E E+L KE N L + D L EN A
Sbjct: 446 KRLKDYESGVYGLEDAVVEIKNCKNQIKIRDREIEILTKEINKLELKISD--FLDENEAL 503
Query: 384 ESEV 387
V
Sbjct: 504 RERV 507
Score = 29.3 bits (64), Expect = 7.3
Identities = 25/130 (19%), Positives = 59/130 (45%), Gaps = 13/130 (10%)
Query: 166 RKLAKIKQDTVSHDRDNMETLVHLIISQDHTIHQQVKRMKELDLEIEKCEAKFHLDRVEN 225
++L ++K+ + + D + H + +D + ++L L+ + K H
Sbjct: 1984 KELEELKKRNLDLENDILYMRAHQALPRDSVV-------EDLHLQNRYLQEKLHALE--- 2033
Query: 226 DGENYVQDAYLMPSFSEVEQNLDLQYEENQTLEDLSESDGIEQLEERLKYYRILIDKLSA 285
+ + +D Y PS S +E + Q E+ E+L S +L+ +L+ + +L
Sbjct: 2034 --KQFSKDTYSKPSISGIESDDHCQREQELQKENLKLSSENIELKFQLEQANKDLPRLKN 2091
Query: 286 EIEKEVKSVC 295
++ +++K +C
Sbjct: 2092 QV-RDLKEMC 2100
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 42.0 bits (97), Expect = 0.001
Identities = 67/313 (21%), Positives = 128/313 (40%), Gaps = 37/313 (11%)
Query: 150 KTLPPDKQKRIVRKTFRKLAKIKQDTVSHD----------RDNMETL----VHLIISQDH 195
+TL + ++VR+ ++A++++D S RD E L L + D
Sbjct: 1102 ETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDT 1161
Query: 196 TIHQQVKRMKELDLEIEKCEAKFHLDRVENDGENYVQDAYLM--PSFSEVEQNLDLQYEE 253
T QQ R K E E E K L+ + E +QD + E+ + L+
Sbjct: 1162 TAAQQELRTKR---EQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRF 1218
Query: 254 NQTLEDLSESDGIEQLEERLKYYRILIDKLSAEIEKEVKSVCIDINE----DAEG----- 304
LE G+E + L ++ ++ AE E + K + + E +EG
Sbjct: 1219 KANLE--KNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRV 1276
Query: 305 ---EAASELESSNLESVKCDLEKSMKAGLKIHSHLSGIQKEIKYSDSLLQMKAKEYELLA 361
E AS+L++ L++V LE++ K G+K + ++ +++ + LLQ + ++ L+
Sbjct: 1277 ELAEKASKLQNE-LDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLS 1335
Query: 362 KEFNSLHISNKDGCQLKENRAKESEVPSSNGEIPPFTQRVFSNYTNDTDSDTGISSNHSQ 421
L ++ L+E + +E E + + Q ++ D D G + +
Sbjct: 1336 SRIRQL---EEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEE 1392
Query: 422 DSETTVGDVVLLS 434
+ + D LS
Sbjct: 1393 AKKKLLKDAEALS 1405
Score = 36.6 bits (83), Expect = 0.046
Identities = 43/188 (22%), Positives = 86/188 (45%), Gaps = 20/188 (10%)
Query: 180 RDNMETLVHLIISQDHTIHQQVKRMKELDLEIEKCEAKFHLDRVENDGENYVQDAYLMPS 239
R +ME L+ +H+ K + L+ ++E E + L+ +E++ + +DA L
Sbjct: 1510 RADMEDLMSSKDDVGKNVHELEKSKRALEQQVE--EMRTQLEELEDELQA-TEDAKL--- 1563
Query: 240 FSEVEQNLDLQYEENQTLEDLSESDGIEQLEERLKYYRILIDKLSAEIEKEVKSVCIDIN 299
+++Q + Q DL D EQ EE+ + + +L AE+E E K + +
Sbjct: 1564 ----RLEVNMQAMKAQFERDLQTRD--EQNEEKKRLLIKQVRELEAELEDERKQRALAV- 1616
Query: 300 EDAEGEAASELESSNLESVKCDLEKSMKAGLKIHSHLSGIQKEIK-YSDSLLQMKAKEYE 358
A+ + +L+ ++ +E + KA ++ L +Q ++K Y L + +A E
Sbjct: 1617 ------ASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDE 1670
Query: 359 LLAKEFNS 366
+ A+ S
Sbjct: 1671 IFAQSKES 1678
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 42.0 bits (97), Expect = 0.001
Identities = 63/308 (20%), Positives = 139/308 (45%), Gaps = 39/308 (12%)
Query: 133 LVQNTEKLWELSPANY--MKTLPPDKQKRIVRKTFRKLAKIKQDTVSHDRDNMETLVHLI 190
L ++ KL E P + + LP K+ ++T +L + + + + D + +
Sbjct: 1271 LEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMER 1330
Query: 191 ISQDHTIHQQVKRMKELDLEIEKCEAKFHLDRVENDG-ENYVQD--AYLMPSFSEVEQNL 247
+ + + + +K L E + + V++D + ++++ A + S S+ EQ+L
Sbjct: 1331 LRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSL 1390
Query: 248 DLQYEENQTLEDLSESDGIEQLEE---RLKYYRILIDKLSAEIEKEVKSVCIDINEDAEG 304
+++ ++N+T + +SE + + + R++ + + K E E+KSV + ++
Sbjct: 1391 NMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRL 1450
Query: 305 EAASELESSNL-ESVK------CDLEKSMKAG-------------LKIH-----SHLSGI 339
+ + ES L E++K + E+ +K L+++ + +S I
Sbjct: 1451 QEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTI 1510
Query: 340 QKEIKYSDSLLQMKAKEYELLAKEFNSLHISN-----KDGCQLKENR-AKESEVPSSNGE 393
QK+++ + LQ K +E ++FN IS + Q KE+R AK+S + S +
Sbjct: 1511 QKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESK 1570
Query: 394 IPPFTQRV 401
+ T R+
Sbjct: 1571 MLELTNRL 1578
Score = 32.3 bits (72), Expect = 0.86
Identities = 41/200 (20%), Positives = 91/200 (45%), Gaps = 30/200 (15%)
Query: 160 IVRKTFRKLAKIKQDTVSHDRDNMETLVHLIISQDHTIHQQVKRMKELDLEIE------K 213
+ +K L ++K +V +RDN+ + + + + + ++ K DLEI+ +
Sbjct: 1873 LAQKLHENLEEMK--SVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTAR 1930
Query: 214 CEAKFHLDRVENDGENYVQDAYLMPSFSEVEQNLDLQYEENQTLEDLSESDGIEQLEERL 273
+K H + V+ E + S+++++LD +E Q I++L++
Sbjct: 1931 MLSKEHKETVDKLREKISEKTI---QISDIQKDLDKSKDELQ--------KKIQELQK-- 1977
Query: 274 KYYRILIDKLSAEIEKEVKSVCIDINEDAEGEAASELESSNLESVKCDLEKSMKAGLKIH 333
K ++L ++++V INE + + E ++ +++SV+ D + + K+H
Sbjct: 1978 KELQLL------RVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMD---NFQLTKKLH 2028
Query: 334 SHLSGIQKEIKYSDSLLQMK 353
L I+ K D L ++K
Sbjct: 2029 ESLEEIRIVAKERDELRRIK 2048
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 41.2 bits (95), Expect = 0.002
Identities = 55/241 (22%), Positives = 110/241 (45%), Gaps = 16/241 (6%)
Query: 138 EKLWELSPANYMKTLPPDKQKRIVRKTFRKLAKIKQDT--VSHDRDNMETLVHLIISQDH 195
EK+ L K +K K + K ++L +++T V + +++ + + +
Sbjct: 951 EKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMR 1010
Query: 196 TIHQQVKRMKELDLEIEKCEAKFHLDRVE-NDGENYVQDAYLMPSFSEVEQNLDLQYEE- 253
+ Q + K L LE EK + +++ N+ E+ ++D + +N LQ E
Sbjct: 1011 DLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIED------LTRQLRNSTLQCETI 1064
Query: 254 NQTLEDLSESDGIEQLEERLKYYRIL-IDKLSAEIEKEVKSVCIDINEDAEGEAASELES 312
N EDL Q +L +IL + + A ++KE+++ + + + A + E
Sbjct: 1065 NSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNE- 1123
Query: 313 SNLESVKCDLEKSMKAGLKIHSHLSGIQKEIKYSDSLLQMKAKEYELLAKEFNSLHISNK 372
LE ++ L+K K K L ++K+ + + +L+ M+ +YE L KE N ++NK
Sbjct: 1124 --LEELQVQLQKEKKQLQKTMQELELVKKDAQQT-TLMNMEIADYERLMKELNQ-KLTNK 1179
Query: 373 D 373
+
Sbjct: 1180 N 1180
Score = 40.8 bits (94), Expect = 0.002
Identities = 53/263 (20%), Positives = 114/263 (43%), Gaps = 41/263 (15%)
Query: 169 AKIKQDTVSHDRDNMETLVHLIISQDHTIHQQVKRMKELDLEIEKCEAKF--HLDRVEND 226
A+ +Q +S ++N I + V +M + E+E+ + ++ ++N+
Sbjct: 86 AETEQQCLSLKKEN--------IKMKQEVEDSVTKMGDAHKELEQSHINYVKEIENLKNE 137
Query: 227 ----GENYVQDAYLMPSFSEVEQNLDLQYEENQTLEDLSESDGIEQLEERLKYYRILIDK 282
Y +D + E N L+ E ++ SE D +++L+E ++ R ++
Sbjct: 138 LMAVRSKYSEDKANLQKQLEEAMNTQLELSEQLKFQNNSE-DNVKKLQEEIEKIRPGFEE 196
Query: 283 LSAEIEKEVKSVCIDINEDAEGEAASELESSNLESVKCDLEKSMKAGLKIHSHLSGI-QK 341
++K+ +D D + E ++L++ +E+ +K++ + + L I Q+
Sbjct: 197 QILYLQKQ-----LDATTDEKKETVTQLQNI-IEANSQHYQKNINSLQEELLQLKAIHQE 250
Query: 342 EIKYSDSLLQMKAKEYELLAKEFNSLHISNKDGCQLKENRAKESEVPSSNGEIPPFTQRV 401
E+K ++ AKE+E E N L+ +LKEN K+ E N +
Sbjct: 251 EVKELMCQIEASAKEHE---AEINKLN-------ELKENLVKQCEASEKN---------I 291
Query: 402 FSNYTNDTDSDTGISSNHSQDSE 424
Y + ++ +SN +QD++
Sbjct: 292 QKKYECELENLRKATSNANQDNQ 314
Score = 38.9 bits (89), Expect = 0.009
Identities = 48/214 (22%), Positives = 92/214 (42%), Gaps = 43/214 (20%)
Query: 130 EAKLVQNTEKLWE-LSPANYMKTLPPD--KQKRIVRKTFRKLAKIKQDTVSHDRDNMETL 186
EA+ +Q +K+ E + N ++ L K+K+ ++KT ++L +K+D NME
Sbjct: 1104 EAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNME-- 1161
Query: 187 VHLIISQDHTIHQQVKRMKELDLEIEKCEAKFHLDRVENDGENYVQDAYLMPSFSEVEQN 246
I + MKEL+ ++ + N ++D +EQ
Sbjct: 1162 ----------IADYERLMKELNQKL-------------TNKNNKIED---------LEQE 1189
Query: 247 LDLQYEENQTLED--LSESDGIEQLEERLKYYRILIDKLSAEI--EKEVKSVCIDINEDA 302
+ +Q ++ +TL++ S ++Q EE+ + L+ K E+ K+ ++ + +
Sbjct: 1190 IKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQASL 1249
Query: 303 EGEAASELESSNLESVKCDLEKSMKAGLKIHSHL 336
+GE E +E K L + KIH HL
Sbjct: 1250 KGEL--EASQQQVEVYKIQLAEITSEKHKIHEHL 1281
>gi|119943086 Tax1 (human T-cell leukemia virus type I) binding
protein 1 isoform b [Homo sapiens]
Length = 747
Score = 40.4 bits (93), Expect = 0.003
Identities = 55/277 (19%), Positives = 112/277 (40%), Gaps = 25/277 (9%)
Query: 144 SPANYMKTLPPD-KQKRIVRKTFRKLAKIKQDTVSHDRDNMETLVHLIISQDHTIHQQVK 202
SP + T+ + +V T L ++K + +++ + L+ ++ + + +QV
Sbjct: 124 SPVEELLTMEDEGNSDMLVVTTKAGLLELKIEKTMKEKEELLKLIAVLEKETAQLREQVG 183
Query: 203 RM-KELDLEIEKCEAKFHLDRVENDGENYVQDAYLMPSFSEVEQNLDLQYEENQTLEDL- 260
RM +EL+ E E+C+ + E G V + M + ++ D + +Q ED+
Sbjct: 184 RMERELNHEKERCDQL----QAEQKGLTEVTQSLKMENEEFKKRFSDATSKAHQLEEDIV 239
Query: 261 -------SESDGIEQLEERLKYYRILIDKLSAEIEKEVKSVCIDINEDAEGEAASELESS 313
+ ++ L+++LK A+ E+E + +D + L+++
Sbjct: 240 SVTHKAIEKETELDSLKDKLK---------KAQHEREQLECQLKTEKDEKELYKVHLKNT 290
Query: 314 NLESVKCDLEKSMKAGLKIHSHLSGIQKEIKYSDSLLQMKAKEYELLAKEFNSLHISNKD 373
+E+ K L ++ + + + K LQ+ E E L + F S +D
Sbjct: 291 EIENTK--LMSEVQTLKNLDGNKESVITHFKEEIGRLQLCLAEKENLQRTFLLTTSSKED 348
Query: 374 GCQLKENRAKESEVPSSNGEIPPFTQRVFSNYTNDTD 410
C LKE K E + + F + S+ N D
Sbjct: 349 TCFLKEQLRKAEEQVQATRQEVVFLAKELSDAVNVRD 385
>gi|21361682 Tax1 (human T-cell leukemia virus type I) binding
protein 1 isoform a [Homo sapiens]
Length = 789
Score = 40.4 bits (93), Expect = 0.003
Identities = 55/277 (19%), Positives = 112/277 (40%), Gaps = 25/277 (9%)
Query: 144 SPANYMKTLPPD-KQKRIVRKTFRKLAKIKQDTVSHDRDNMETLVHLIISQDHTIHQQVK 202
SP + T+ + +V T L ++K + +++ + L+ ++ + + +QV
Sbjct: 124 SPVEELLTMEDEGNSDMLVVTTKAGLLELKIEKTMKEKEELLKLIAVLEKETAQLREQVG 183
Query: 203 RM-KELDLEIEKCEAKFHLDRVENDGENYVQDAYLMPSFSEVEQNLDLQYEENQTLEDL- 260
RM +EL+ E E+C+ + E G V + M + ++ D + +Q ED+
Sbjct: 184 RMERELNHEKERCDQL----QAEQKGLTEVTQSLKMENEEFKKRFSDATSKAHQLEEDIV 239
Query: 261 -------SESDGIEQLEERLKYYRILIDKLSAEIEKEVKSVCIDINEDAEGEAASELESS 313
+ ++ L+++LK A+ E+E + +D + L+++
Sbjct: 240 SVTHKAIEKETELDSLKDKLK---------KAQHEREQLECQLKTEKDEKELYKVHLKNT 290
Query: 314 NLESVKCDLEKSMKAGLKIHSHLSGIQKEIKYSDSLLQMKAKEYELLAKEFNSLHISNKD 373
+E+ K L ++ + + + K LQ+ E E L + F S +D
Sbjct: 291 EIENTK--LMSEVQTLKNLDGNKESVITHFKEEIGRLQLCLAEKENLQRTFLLTTSSKED 348
Query: 374 GCQLKENRAKESEVPSSNGEIPPFTQRVFSNYTNDTD 410
C LKE K E + + F + S+ N D
Sbjct: 349 TCFLKEQLRKAEEQVQATRQEVVFLAKELSDAVNVRD 385
>gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens]
Length = 971
Score = 40.4 bits (93), Expect = 0.003
Identities = 56/265 (21%), Positives = 112/265 (42%), Gaps = 46/265 (17%)
Query: 155 DKQKRIVRKTFRKLAKIKQDTVSHDRDNMETLVHLIISQDHTIHQQVKRM-----KELDL 209
D++K R +++K + + +S + N+E + +SQ T QQ++ + L
Sbjct: 556 DREKNAARDSWQKKVEDLLNQISLLKQNLE----IQLSQSQTSLQQLQAQFTQERQRLTQ 611
Query: 210 EIEKCEAKFHLDRVENDGENYVQDAYLMPSFSEVEQNL---DLQYEENQTLEDLSESDGI 266
E+E+ E + H R ++ E +V M E EQ LQ + + L+ L ++
Sbjct: 612 ELEELEEQ-HQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHLQQKHSAELQSLKDAH-- 668
Query: 267 EQLEERLKYYRILIDK----LSAEIEKEVKSVCIDINEDAEGEAASELE------SSNLE 316
E ++ +RI +++ L E+E E K++ + + + A+ ++ L
Sbjct: 669 ---RESMEGFRIEMEQELQTLRFELEDEGKAMLASLRSELNHQHAAAIDLLRHNHHQELA 725
Query: 317 SVKCDLEKSM---KAGLKIH---------------SHLSGIQKEIKYSDSLLQMKAKEYE 358
+ K +LE+S+ + K H H+S + KE+++ + KE E
Sbjct: 726 AAKMELERSIDISRRQSKEHICRITDLQEELRHREHHISELDKEVQHLHENISALTKELE 785
Query: 359 LLAKEFNSLHISNKDGCQLKENRAK 383
KE + + +L+E K
Sbjct: 786 FKGKEILRIRSESNQQIRLEEMEEK 810
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 40.0 bits (92), Expect = 0.004
Identities = 63/295 (21%), Positives = 128/295 (43%), Gaps = 48/295 (16%)
Query: 132 KLVQNTEKLWELSPANYMK-----TLPPDKQKRIVRKTFRKLAKIKQDTVSHDRDNMETL 186
K ++N +L ++ ++++ T + +R + + +K A++ Q+ +S +++ +
Sbjct: 2591 KNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAEL-QEELSGEKNRLAGE 2649
Query: 187 VHLIISQDHTIHQQVKRMKELDLEIEKCEAKFHLDRVENDGENYVQDAYLMPSFSEVE-- 244
+ L++ + + Q+K + + E++K H D+VE +G+ + A E E
Sbjct: 2650 LQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKK 2709
Query: 245 -QNLDLQYEENQTLEDLSESDGIEQLEERLKYYRILID-------------KLSAEIEKE 290
Q L L + +E + + + EE L ++ ID K + +I +E
Sbjct: 2710 HQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEE 2769
Query: 291 VKSVCID----------INEDAEGEAASELES-SNLESVKCDLEKSM----------KAG 329
+K +D NE A+G+ ++S LE K L+K + K G
Sbjct: 2770 LKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTG 2829
Query: 330 LKIHSHLSGIQKEIKYSDSLLQMKAKEYELLAKEFNSLHISNKDGCQLKENRAKE 384
+ + + + EIK L+ K KE + ++ SL IS++ K +AKE
Sbjct: 2830 TVMDTKVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHE-----KLEKAKE 2879
Score = 36.6 bits (83), Expect = 0.046
Identities = 61/263 (23%), Positives = 109/263 (41%), Gaps = 28/263 (10%)
Query: 129 AEAKLVQNTEKLWELSPANYMKTLPPDKQKRIVRKTFRKLAKIKQDTVSHDRDNMETLVH 188
A K +KL +L+ + + + + + ++ K Q+ +S + + +TL
Sbjct: 353 ASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQ 412
Query: 189 LIISQDHTIHQQVKRMKELD--LEIEKCEAKFHLDRVENDGENYVQ------DAYLMPSF 240
I + Q++++ K + L+ E + ++EN+ E + Q A+
Sbjct: 413 ECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQI 472
Query: 241 SEVE--QNLDLQYEENQTLEDLSESDGIE--QLEERLKYYRILIDKLS--AEIEKEVKSV 294
E E ++++ +EN L+ SE E LE LK + +++ AE K +
Sbjct: 473 KENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTS 532
Query: 295 CIDINEDAEGEAASELESSNLESVK---CDLEKSMKAG---LKIHSH--------LSGIQ 340
+ D + + + S LE +K DLEK LK H LS +
Sbjct: 533 QETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTE 592
Query: 341 KEIKYSDSLLQMKAKEYELLAKE 363
KE K S L++K KEYE L +E
Sbjct: 593 KESKALLSALELKKKEYEELKEE 615
Score = 33.5 bits (75), Expect = 0.39
Identities = 45/173 (26%), Positives = 79/173 (45%), Gaps = 22/173 (12%)
Query: 192 SQDHTIHQQVKRMKELDLEIEKCEAK-FHLDRV------ENDG-ENYVQDAYLMPSFSEV 243
S +HQ + +++L + IE E K H+ END ++ V++ SE
Sbjct: 2109 STQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEE 2168
Query: 244 EQNLDLQYEENQTLEDLSESDGIEQLEERLKYYRILIDKLSAEIEKEVKSVCIDINEDAE 303
Q L + EN E + IE++ LK + + + L +E E K + ++ +
Sbjct: 2169 NQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQI-----QEKQ 2223
Query: 304 GEAASELESSNLESVKCDLEKSMKAGLKIHSHLSGIQKEIKYSDSLLQMKAKE 356
G+ SEL+ L S K LE+ +A ++ I++E K + +LQ + KE
Sbjct: 2224 GQ-LSELDKL-LSSFKSLLEEKEQAEIQ-------IKEESKTAVEMLQNQLKE 2267
Score = 31.6 bits (70), Expect = 1.5
Identities = 27/114 (23%), Positives = 56/114 (49%), Gaps = 11/114 (9%)
Query: 252 EENQTLEDL--SESDGIEQLEERLKYYRILIDKLSAEIEKEVKSVCIDINEDAEGEAASE 309
EEN T ++ + + G+E+LE + YR ++KL ++E + I ++ E + +
Sbjct: 1533 EENLTRKETPSAPAKGVEELESLCEVYRQSLEKLEEKMESQ------GIMKNKEIQELEQ 1586
Query: 310 LESSNLESVKCDLEKSMKAGLKIHSHLSGIQKEIKYSDSLLQMKAKEYELLAKE 363
L SS + + C ++ + + L+ + E+ +S L + K+ E L+ E
Sbjct: 1587 LLSSERQELDCLRKQYLSENEQWQQKLTSVTLEM---ESKLAAEKKQTEQLSLE 1637
Score = 31.6 bits (70), Expect = 1.5
Identities = 48/228 (21%), Positives = 86/228 (37%), Gaps = 36/228 (15%)
Query: 186 LVHLIISQDHTIHQQVKRMKELDLEIE--------KCEAKFHLDRVENDGENYVQD---- 233
L+H+I +D + + MKELD ++ K EA L+++ + + D
Sbjct: 1786 LLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEK 1845
Query: 234 -AYLMPSFSEVEQNLDLQYEENQTLEDLSESDGIEQLEERL----------------KYY 276
Y E+ Q ++ N LE ++ E + + + +
Sbjct: 1846 LEYFSCDHQELLQRVETSEGLNSDLEMHADKSSREDIGDNVAKVNDSWKERFLDVENELS 1905
Query: 277 RILIDKLSAEIEKEVKSVCIDINEDAEGEAASELESSNLESVKCDLEKSMKAGLKIHSHL 336
RI +K A IE E + D+ + E ++ N + V LE+ + + L
Sbjct: 1906 RIRSEK--ASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQL 1963
Query: 337 SG----IQKEIKYSDSLLQ-MKAKEYELLAKEFNSLHISNKDGCQLKE 379
G + K+ D L + MK K EL + + LH ++KE
Sbjct: 1964 RGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKE 2011
Score = 30.0 bits (66), Expect = 4.3
Identities = 49/230 (21%), Positives = 99/230 (43%), Gaps = 28/230 (12%)
Query: 161 VRKTFRKLAKIKQDTVSHDRDNMETLVHLIISQDHTIHQQVKRMKELDLEIEKCEAKFHL 220
V +T ++++K+++DT +H ETL L + KEL L +K E +
Sbjct: 878 VAETSQRISKLQEDTSAHQNVVAETLSAL-----------ENKEKELQLLNDKVETEQAE 926
Query: 221 DRVENDGENYVQDAYLMPSFSEVEQNLDLQYEENQTLEDLSESDGIEQLEER---LKYYR 277
+ + ++D+ + + + L L+ +E ++ L++ + IE+L + LK
Sbjct: 927 IQELKKSNHLLEDS--LKELQLLSETLSLEKKEMSSIISLNKRE-IEELTQENGTLKEIN 983
Query: 278 ILIDKLSAEIEKEVKSVCIDINEDAEGEAASELESSNLESVKCDLEKSMKAGLKIHSHLS 337
+++ + ++ +S I+E ++ SEL + L++ + G
Sbjct: 984 ASLNQEKMNLIQKSESFANYIDE--REKSISELSDQYKQEKLILLQRCEETG-------- 1033
Query: 338 GIQKEIKYSDSLLQMKAKEYELLAKEFNSLHISNKDGC-QLKENRAKESE 386
+++ Q K + E L E SL + K+ QLKE AKE +
Sbjct: 1034 NAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQ 1083
>gi|21735569 claspin [Homo sapiens]
Length = 1339
Score = 39.7 bits (91), Expect = 0.005
Identities = 58/256 (22%), Positives = 98/256 (38%), Gaps = 46/256 (17%)
Query: 107 QPNMQFVLVKADAFLPV--------------PLWRTAEAKLVQNTEKLWELSPANYMKTL 152
+ + Q L+ AD FL V PL E + N ++L +L +
Sbjct: 864 EDDTQSQLLDADGFLNVRNHRNQYQALKPRLPLASMDENAMDANMDELLDLCTGKFTS-- 921
Query: 153 PPDKQKRIVRKTFRKLAKIKQDTVSHDRDNMETLVHL----IISQDHT------IHQQVK 202
+K + RK+ +K +NME L++L SQD + +++Q K
Sbjct: 922 --QAEKHLPRKSDKK-------------ENMEELLNLCSGKFTSQDASTPASSELNKQEK 966
Query: 203 RMK---ELDLEIEKCEAKFHLDRVENDGENYVQDAYLMPSFSEVEQNLDLQYEENQ--TL 257
++ + C F D+ E D E D L+ + +E + + D + L
Sbjct: 967 ESSMGDPMEEALALCSGSFPTDKEEEDEEEEFGDFRLVSNDNEFDSDEDEHSDSGNDLAL 1026
Query: 258 EDLSESDGIEQLEERLKYYRILIDKLSAEIEKEVKSVCIDINEDAEGEAASELESSNLES 317
ED + D E L+ K R + + E E EV + ++ +GE E E ++
Sbjct: 1027 EDHEDDDEEELLKRSEKLKRQMRLRKYLEDEAEVSGSDVGSEDEYDGEEIDEYEEDVIDE 1086
Query: 318 VKCDLEKSMKAGLKIH 333
V E+ KIH
Sbjct: 1087 VLPSDEELQSQIKKIH 1102
Score = 29.6 bits (65), Expect = 5.6
Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 12/83 (14%)
Query: 244 EQNLDLQYEENQTLEDLSESDGIEQLEERLKYYRILIDKLSAEIEKEVKSVCIDINEDAE 303
E + + EE + + D SE DG E++E+ K ++L E EKE + E+
Sbjct: 625 EDGFEEEEEEEEEMTDESEEDGEEKVEKEEKE-----EELEEEEEKEEEE-----EEEGN 674
Query: 304 GEAASELESSNLESVKCDLEKSM 326
E A L SS E ++ EK M
Sbjct: 675 QETAEFLLSS--EEIETKDEKEM 695
>gi|7705415 hook homolog 1 [Homo sapiens]
Length = 728
Score = 39.7 bits (91), Expect = 0.005
Identities = 48/215 (22%), Positives = 102/215 (47%), Gaps = 14/215 (6%)
Query: 142 ELSPANYMKTLPPDKQKRIVRKTFRKLAKIKQ--DTVSHDRDNMETLVHLIISQDHTIHQ 199
EL AN +T + KR V+ KL+ + DT++ + +E ++ + + +
Sbjct: 360 ELKKANAART-QLETYKRQVQDLHVKLSSESKRADTLAFEMKRLEEKHEALLKEKERLIE 418
Query: 200 QVKRMKELDLEIEKCEAKF-HLDRVENDGENYVQD--AYLMP-SFSEVEQNLDLQYEENQ 255
Q +KE + E+ + + HL++ + ++ A +MP + EV L + + +
Sbjct: 419 QRDTLKETNEELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEYREVFIRLQHENKMLR 478
Query: 256 TLEDLSESDGIEQLEERLKYYRILID------KLSAEIEKEVKSVCIDINEDAEGEAASE 309
++ SE++ IE+L+E+L+ ++ +LS E +E++ D+ + + E S+
Sbjct: 479 LQQEGSENERIEELQEQLEQKHRKMNELETEQRLSKERIRELQQQIEDLQKSLQ-EQGSK 537
Query: 310 LESSNLESVKCDLEKSMKAGLKIHSHLSGIQKEIK 344
E + +K LE M+ ++H L Q+ I+
Sbjct: 538 SEGESSSKLKQKLEAHMEKLTEVHEELQKKQELIE 572
>gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens]
Length = 1140
Score = 39.7 bits (91), Expect = 0.005
Identities = 58/272 (21%), Positives = 115/272 (42%), Gaps = 49/272 (18%)
Query: 155 DKQKRIVRKTFRKLAKIKQDTVSHDRDNMETLVHLIISQDHTIHQQVKRM-----KELDL 209
D++K R +++K + + +S + N+E + +SQ T QQ++ + L
Sbjct: 676 DREKNAARDSWQKKVEDLLNQISLLKQNLE----IQLSQSQTSLQQLQAQFTQERQRLTQ 731
Query: 210 EIEKCEAKFHLDRVENDGENYVQDAYLMPSFSEVEQNL---DLQYEENQTLEDLSESDGI 266
E+E+ E + H R ++ E +V M E EQ LQ + + L+ L ++
Sbjct: 732 ELEELEEQ-HQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHLQQKHSAELQSLKDAH-- 788
Query: 267 EQLEERLKYYRILIDK----LSAEIEKEVKSVCIDINEDAEGEAASELE------SSNLE 316
E ++ +RI +++ L E+E E K++ + + + A+ ++ L
Sbjct: 789 ---RESMEGFRIEMEQELQTLRFELEDEGKAMLASLRSELNHQHAAAIDLLRHNHHQELA 845
Query: 317 SVKCDLEKSM---KAGLKIH---------------SHLSGIQKEIKYSDSLLQMKAKEYE 358
+ K +LE+S+ + K H H+S + KE+++ + KE E
Sbjct: 846 AAKMELERSIDISRRQSKEHICRITDLQEELRHREHHISELDKEVQHLHENISALTKELE 905
Query: 359 LLAKEFNSLHISNKDGCQLKE---NRAKESEV 387
KE + + +L E N+ E E+
Sbjct: 906 FKGKEILRIRSESNQQIRLHEQDLNKRLEKEL 937
>gi|5031741 DnaJ subfamily A member 2 [Homo sapiens]
Length = 412
Score = 39.3 bits (90), Expect = 0.007
Identities = 29/109 (26%), Positives = 57/109 (52%), Gaps = 13/109 (11%)
Query: 277 RILIDKLSAEIEKEVKSVCIDINEDAEGEAASELES----------SNLESVKCDLEKSM 326
RI+I +L+ + ++++SVC D N EGE +E + ++ ++ ++K M
Sbjct: 168 RIMIRQLAPGMVQQMQSVCSDCN--GEGEVINEKDRCKKCEGKKVIKEVKILEVHVDKGM 225
Query: 327 KAGLKIHSHLSGIQKE-IKYSDSLLQMKAKEYELLAKEFNSLHISNKDG 374
K G +I Q ++ D +L ++ KE+E+ ++ N LH++ K G
Sbjct: 226 KHGQRITFTGEADQAPGVEPGDIVLLLQEKEHEVFQRDGNDLHMTYKIG 274
>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
Length = 976
Score = 39.3 bits (90), Expect = 0.007
Identities = 42/209 (20%), Positives = 83/209 (39%), Gaps = 10/209 (4%)
Query: 194 DHTIHQQVKRMKELDLEIEKCEAKFHLDRVENDGENYVQDAYLMPSFSEVEQNLDLQYEE 253
D T + + E D E + + D + +Q +P +V N D Y+E
Sbjct: 31 DSTFFKSFNKCTEDDFEFPFAKTNLSKNGENIDSDPALQKVNFLPVLEQVG-NSDCHYQE 89
Query: 254 NQTLEDLSESDGIEQLEERLKYYRILIDKLSAEIEKEVKSVCIDINE-----DAEGEAAS 308
DL S+G+ ++ +L I K E E++ + E +A+ +A
Sbjct: 90 GLKDSDLENSEGLSRVYSKLYKEAEKIKKWKVSTEAELRQKESKLQENRKIIEAQRKAIQ 149
Query: 309 ELESSNLESVKCDLEKSMKAG---LKIHSHLSGIQKEIKYSDSLLQMKAKEYELLAKEFN 365
EL+ N E V LE+ ++ +K ++ + +K + + K K+YE +E
Sbjct: 150 ELQFGN-EKVSLKLEEGIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYEREETR 208
Query: 366 SLHISNKDGCQLKENRAKESEVPSSNGEI 394
+++ + + +E V + N +
Sbjct: 209 QVYMDLNNNIEKMITAFEELRVQAENSRL 237
Score = 39.3 bits (90), Expect = 0.007
Identities = 70/376 (18%), Positives = 158/376 (42%), Gaps = 40/376 (10%)
Query: 16 RSPTKDMDSEEKEIVVWVCQEEKLVCGLTKRTTSADVIQALLEEHEATFGEKRFLLGKPS 75
R+ + ++ E ++ + + +K L + T + + LEE + GEK LL +
Sbjct: 392 RTEQQRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENK 451
Query: 76 DY-CIIEKWRGSERVLPPLTRILKLWKAWGDEQPNMQFVLVKADAFLPVPLWRTAEAKLV 134
+ I E+ +G+E+ ++ L +A E +++ L + K
Sbjct: 452 QFEKIAEELKGTEQ------ELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTE 505
Query: 135 QNTEKLWELSPANYMKTLPPDKQKRIVRKTFRKLAKIK--QDTVSHDRDNMETLVHLIIS 192
EKL ++ L + K + ++T ++K Q+ +++++ E ++ I +
Sbjct: 506 LENEKLKNTELTSHCNKLSLE-NKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIEN 564
Query: 193 QDHT---IHQQVKRMKELDLEIEKCEAKFHLDRVENDGENYVQDAYLMPSFSEVEQNLDL 249
T + +++ ++E +L+ ++ E K LD+ E + N L + ++
Sbjct: 565 LQETETQLRNELEYVRE-ELKQKRDEVKCKLDKSEENCNN------LRKQVENKNKYIEE 617
Query: 250 QYEENQTLEDLSESDGIEQLEERLKYYRILIDKLSAEIEK---------EVKSVCIDINE 300
+EN+ L+ ++ ++L Y I ++KL E+E + I+ +
Sbjct: 618 LQQENKALKKKGTAE-----SKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKK 672
Query: 301 DAEGEAASELESSNL---ESVKCDLEKSMKAGLKIHSHLSGIQKEIKYSDSLLQMKAKE- 356
+E E+E + + E+VK E + KI ++ ++K D +++ + E
Sbjct: 673 ISEENLLEEVEKAKVIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSEL 732
Query: 357 --YELLAKEFNSLHIS 370
Y+ +E +SL S
Sbjct: 733 GLYKSKEQEQSSLRAS 748
>gi|64085252 hypothetical protein LOC145508 [Homo sapiens]
Length = 1094
Score = 38.9 bits (89), Expect = 0.009
Identities = 45/197 (22%), Positives = 87/197 (44%), Gaps = 28/197 (14%)
Query: 172 KQDTVSHDRDNMETLVHLIISQDHTIHQQVKRMKELDLEIEKCEA-KFHLDRVENDGENY 230
K +H +E L + + + Q + R+KE+ + CEA + H D ++ +
Sbjct: 391 KDKEKAHLASQVENLTRELENGEKQQLQMLDRLKEIQNHFDTCEAERKHADLQISELTRH 450
Query: 231 VQDAYLMPS--FSEVEQNLDLQYEENQTLEDLSESDGIEQLEERLKYYRILIDKLSAEIE 288
+DA SE++Q+ L+ E + EDL + +E ++ +++ KL +E
Sbjct: 451 AEDATKQAERYLSELQQSEALKEEAEKRREDLK-----LKAQESIRQWKLKHKKLERALE 505
Query: 289 KEVKSVCIDINEDAEGEAASELESSNLESV--KCDLEKSMKAGLKIHSHLSGIQKEIKYS 346
K + E EL N + + K +L+ + A L+ + ++KE+ +
Sbjct: 506 K-------------QSETVDELTGKNNQILKEKDELKTQLYAALQ---QIENLRKEL--N 547
Query: 347 DSLLQMKAKEYELLAKE 363
D L + +E EL +KE
Sbjct: 548 DVLTKRALQEEELHSKE 564
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sapiens]
Length = 1116
Score = 38.5 bits (88), Expect = 0.012
Identities = 60/276 (21%), Positives = 122/276 (44%), Gaps = 35/276 (12%)
Query: 166 RKLAKIKQDTVSHDRDNMETLVHLIISQDHTIHQQVKRMKELDLEIEKCEAKF----HLD 221
R++ + K ++ S + ++ L+ ++ ++ + + K++ EL+ +++ K H +
Sbjct: 742 REITRYKDES-SKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKE 800
Query: 222 RVENDGENYVQDAYLMPSFSEVEQNLDLQYEENQTLEDL--SESDGIEQLEERLKYYRIL 279
+VE + A ++ E NL+ + +Q L+D + D IE+LEE L+ +
Sbjct: 801 QVEKK-----KSAQMLEEARRREDNLN---DSSQQLQDSLRKKDDRIEELEEALRESVQI 852
Query: 280 IDKLSAEIEKEVKSVCIDINEDAEGEAASELESSNLESVKCDLEKSMKAGLKIHSHLSGI 339
+ + +E + + E A E LES+K L + ++ + +HL+ +
Sbjct: 853 TAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNL 912
Query: 340 QKE-IKYSDSLLQMKAKEYELLAKEFNSLHISNKDG----CQLKENRAK-ESEVPSSNGE 393
+ E K+ + +L+M K+ LLA IS KD +L ++ K + EV + E
Sbjct: 913 RAERRKHLEEVLEM--KQEALLAA------ISEKDANIALLELSSSKKKTQEEVAALKRE 964
Query: 394 IPPFTQRVFSNYTN------DTDSDTGISSNHSQDS 423
Q++ N D D S+HS +
Sbjct: 965 KDRLVQQLKQQTQNRMKLMADNYEDDHFKSSHSNQT 1000
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 38.5 bits (88), Expect = 0.012
Identities = 60/276 (21%), Positives = 122/276 (44%), Gaps = 35/276 (12%)
Query: 166 RKLAKIKQDTVSHDRDNMETLVHLIISQDHTIHQQVKRMKELDLEIEKCEAKF----HLD 221
R++ + K ++ S + ++ L+ ++ ++ + + K++ EL+ +++ K H +
Sbjct: 714 REITRYKDES-SKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKE 772
Query: 222 RVENDGENYVQDAYLMPSFSEVEQNLDLQYEENQTLEDL--SESDGIEQLEERLKYYRIL 279
+VE + A ++ E NL+ + +Q L+D + D IE+LEE L+ +
Sbjct: 773 QVEKK-----KSAQMLEEARRREDNLN---DSSQQLQDSLRKKDDRIEELEEALRESVQI 824
Query: 280 IDKLSAEIEKEVKSVCIDINEDAEGEAASELESSNLESVKCDLEKSMKAGLKIHSHLSGI 339
+ + +E + + E A E LES+K L + ++ + +HL+ +
Sbjct: 825 TAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNL 884
Query: 340 QKE-IKYSDSLLQMKAKEYELLAKEFNSLHISNKDG----CQLKENRAK-ESEVPSSNGE 393
+ E K+ + +L+M K+ LLA IS KD +L ++ K + EV + E
Sbjct: 885 RAERRKHLEEVLEM--KQEALLAA------ISEKDANIALLELSSSKKKTQEEVAALKRE 936
Query: 394 IPPFTQRVFSNYTN------DTDSDTGISSNHSQDS 423
Q++ N D D S+HS +
Sbjct: 937 KDRLVQQLKQQTQNRMKLMADNYEDDHFKSSHSNQT 972
>gi|126362969 Nck-associated protein 5 isoform 2 [Homo sapiens]
Length = 590
Score = 38.1 bits (87), Expect = 0.016
Identities = 40/177 (22%), Positives = 79/177 (44%), Gaps = 34/177 (19%)
Query: 156 KQKRIVRKTFRKLAKIKQDTVSHDRDNMETLVHLIISQDHTIHQQVKRMKELDLEIEKCE 215
++K V + R++A+ + H++ L+H + + H Q KR++E+ LE E+
Sbjct: 48 REKLAVARLQREVAQRTSEGAMHEK-----LIHELEEERHLRLQSEKRLQEVTLESER-- 100
Query: 216 AKFHLDRVENDGENYVQDAYLMPSFSEVEQNLDLQYEENQTLEDLSESDGI-EQLEERLK 274
N +Q L FS +E +T+ +L +S G EQ +E
Sbjct: 101 -------------NRIQMRSLQQQFSRME----------ETVRNLLQSQGSPEQKKEETV 137
Query: 275 YYRILIDKLSAEIEKE---VKSVCIDINEDAEGEAASELESSNLESVKCDLEKSMKA 328
+ +KLS E K ++ + + ++ED+ E++S E + + K+++A
Sbjct: 138 NIMVYQEKLSEEERKHKEALEDLHMVVDEDSRSESSSTDEGKEKTKLLLERLKALEA 194
>gi|126362967 Nck-associated protein 5 isoform 1 [Homo sapiens]
Length = 1909
Score = 38.1 bits (87), Expect = 0.016
Identities = 40/177 (22%), Positives = 79/177 (44%), Gaps = 34/177 (19%)
Query: 156 KQKRIVRKTFRKLAKIKQDTVSHDRDNMETLVHLIISQDHTIHQQVKRMKELDLEIEKCE 215
++K V + R++A+ + H++ L+H + + H Q KR++E+ LE E+
Sbjct: 48 REKLAVARLQREVAQRTSEGAMHEK-----LIHELEEERHLRLQSEKRLQEVTLESER-- 100
Query: 216 AKFHLDRVENDGENYVQDAYLMPSFSEVEQNLDLQYEENQTLEDLSESDGI-EQLEERLK 274
N +Q L FS +E +T+ +L +S G EQ +E
Sbjct: 101 -------------NRIQMRSLQQQFSRME----------ETVRNLLQSQGSPEQKKEETV 137
Query: 275 YYRILIDKLSAEIEKE---VKSVCIDINEDAEGEAASELESSNLESVKCDLEKSMKA 328
+ +KLS E K ++ + + ++ED+ E++S E + + K+++A
Sbjct: 138 NIMVYQEKLSEEERKHKEALEDLHMVVDEDSRSESSSTDEGKEKTKLLLERLKALEA 194
>gi|41872583 Rho-associated, coiled-coil containing protein kinase 2
[Homo sapiens]
Length = 1388
Score = 37.7 bits (86), Expect = 0.021
Identities = 53/249 (21%), Positives = 105/249 (42%), Gaps = 28/249 (11%)
Query: 156 KQKRIVRKTFRKLA-KIKQDT-----VSHDRDNMETLVHLIISQDHTIHQQVKRMKELDL 209
KQK ++ + R L KI+Q+T +D V+ + + + Q+ + E+ +
Sbjct: 780 KQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKM 839
Query: 210 EIEKCEAKFHLDRVENDGENYVQDAYLMPSFSEVEQNLDLQYEENQTLEDLSESDGIEQL 269
+EK A+ +R + DG+ E++ L+ + + TL + E+
Sbjct: 840 NLEKQNAELRKERQDADGQ-----------MKELQDQLEAE-QYFSTLYKTQVRELKEEC 887
Query: 270 EERLKYYRILIDKLSAEIEKEVKSVCIDINEDAEGEAASELESSNLESVKCDLEK-SMKA 328
EE+ K + L K E++ E S+ + + +L S E DLEK +
Sbjct: 888 EEKTKLGKELQQK-KQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMK 946
Query: 329 GLKIHSHLSGIQKEIKYSDSLL-------QMKAKEYELLAKEFNSLHISNKDGCQLKENR 381
L+I ++ ++E+ D+ + + + LA E L+ KD Q + +R
Sbjct: 947 ELEIKEMMARHKQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKD-VQEQLSR 1005
Query: 382 AKESEVPSS 390
K+ E+ ++
Sbjct: 1006 LKDEEISAA 1014
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 37.7 bits (86), Expect = 0.021
Identities = 52/232 (22%), Positives = 107/232 (46%), Gaps = 30/232 (12%)
Query: 141 WELSPANYMKTLPPDKQKRIVRKTFRKLAKIKQDTVSHDRDNMETLVHLIISQDHTIHQQ 200
+EL +++K D + R+V++ K+++++ + + +R+N + L I + Q
Sbjct: 1047 YELEAKSHLK----DDRSRLVKQMEDKVSQLEME-LEEERNNSDLLSERISRSREQMEQL 1101
Query: 201 -----VKRMKELDLEIEKCEAKFHLDRVENDGENYVQDAYLMPSFSEVEQNLDLQYEEN- 254
+R DLE +K L+R D ++ + +L S+ ++ L +Q E
Sbjct: 1102 RNELLQERAARQDLECDKIS----LERQNKDLKSRI--IHLEGSYRSSKEGLVVQMEARI 1155
Query: 255 QTLEDLSESDGIEQ---------LEERLKYYRILIDK--LSAEIEKEVKSVCIDINEDAE 303
LED ES+ ++ LE ++K + +D LS +K+ S+ + +
Sbjct: 1156 AELEDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLRLKAMKRQV 1215
Query: 304 GEAASELESSNLESVKCDLEKSMKAGLKIHSHLSGIQKEIKYSDSLLQMKAK 355
EA E++ LES K L++ ++ + ++ HL G +K L ++ +K
Sbjct: 1216 EEAEEEID--RLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPSK 1265
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,338,730
Number of Sequences: 37866
Number of extensions: 734065
Number of successful extensions: 2382
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 205
Number of HSP's that attempted gapping in prelim test: 2230
Number of HSP's gapped (non-prelim): 346
length of query: 435
length of database: 18,247,518
effective HSP length: 105
effective length of query: 330
effective length of database: 14,271,588
effective search space: 4709624040
effective search space used: 4709624040
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.