Guide to the Human Genome
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Name: ROCK2 Sequence: fasta or formatted (1388aa) NCBI GI: 41872583
Description:

Rho-associated, coiled-coil containing protein kinase 2

Referenced in:

Coiled-Coil Proteins
Rho and Rac

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.0         83           3
 C cysteine            1.4         20           1
 D aspartate           6.5         90           2
 E glutamate          11.2        156           3
 F phenylalanine       2.7         37           2
 G glycine             3.3         46           2
 H histidine           1.9         27           1
 I isoleucine          4.8         66           2
 K lysine             10.4        144           2
 L leucine            10.7        149           4
 M methionine          3.0         41           2
 N asparagine          4.8         67           2
 P proline             3.5         49           3
 Q glutamine           6.6         91           2
 R arginine            5.5         76           2
 S serine              6.1         85           3
 T threonine           4.2         58           1
 V valine              4.3         59           2
 W tryptophan          0.8         11           2
 Y tyrosine            2.4         33           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   Rho-associated, coiled-coil containing protein kinas... 
ROCK1                 0.639   Rho-associated, coiled-coil containing protein kinase...
CDC42BPB              0.161   CDC42-binding protein kinase beta 
CDC42BPA              0.159   CDC42-binding protein kinase alpha isoform B 
CDC42BPA              0.156   CDC42-binding protein kinase alpha isoform A 
CIT                   0.151   citron 
CDC42BPG              0.145   CDC42 binding protein kinase gamma (DMPK-like) [Hom...
DMPK                  0.125   myotonic dystrophy protein kinase isoform 4 
DMPK                  0.125   myotonic dystrophy protein kinase isoform 3 
DMPK                  0.124   myotonic dystrophy protein kinase isoform 2 
DMPK                  0.117   myotonic dystrophy protein kinase isoform 1 
PRKACB                0.074   cAMP-dependent protein kinase catalytic subunit beta...
PRKACB                0.073   cAMP-dependent protein kinase catalytic subunit beta ...
PRKX                  0.072   protein kinase, X-linked 
MAST1                 0.071   microtubule associated serine/threonine kinase 1 [Ho...
MAST4                 0.070   microtubule associated serine/threonine kinase fami...
PRKACG                0.070   protein kinase, cAMP-dependent, catalytic, gamma [Ho...
PRKACA                0.070   cAMP-dependent protein kinase catalytic subunit alph...
PRKACA                0.070   cAMP-dependent protein kinase catalytic subunit alpha...
MAST2                 0.069   microtubule associated serine/threonine kinase 2 [H...
MAST3                 0.069   microtubule associated serine/threonine kinase 3 [H...
PRKCE                 0.066   protein kinase C, epsilon 
PRKCQ                 0.064   protein kinase C, theta 
PRKCB                 0.064   protein kinase C, beta isoform 1 
LOC727758             0.063   PREDICTED: similar to Rho-associated, coiled-coil c...
PRKG1                 0.063   protein kinase, cGMP-dependent, type I isoform 1 [H...
PRKG1                 0.063   protein kinase, cGMP-dependent, type I isoform 2 [Ho...
PRKCH                 0.062   protein kinase C, eta 
AKT2                  0.062   AKT2 kinase 
RPS6KA2               0.062   ribosomal protein S6 kinase, 90kDa, polypeptide 2 is...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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