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Search of human proteins with 217416332
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|217416332 trinucleotide repeat containing 6C isoform 1 [Homo
sapiens]
(1726 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|217416332 trinucleotide repeat containing 6C isoform 1 [Homo ... 3576 0.0
gi|33413425 trinucleotide repeat containing 6C isoform 2 [Homo s... 3458 0.0
gi|116805348 trinucleotide repeat containing 6A [Homo sapiens] 1207 0.0
gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo ... 920 0.0
gi|148491080 trinucleotide repeat containing 6B isoform 2 [Homo ... 652 0.0
gi|67782330 trinucleotide repeat containing 6B isoform 3 [Homo s... 573 e-163
gi|57864582 hornerin [Homo sapiens] 105 5e-22
gi|62122917 filaggrin family member 2 [Homo sapiens] 81 8e-15
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 77 1e-13
gi|169173184 PREDICTED: hypothetical protein [Homo sapiens] 72 5e-12
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 70 1e-11
gi|161016767 mucin 21 [Homo sapiens] 68 7e-11
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 67 2e-10
gi|186928827 dermokine isoform 5 precursor [Homo sapiens] 60 2e-08
gi|186928829 dermokine isoform 4 precursor [Homo sapiens] 60 2e-08
gi|186928825 dermokine isoform 3 precursor [Homo sapiens] 60 2e-08
gi|33504489 dermokine isoform 2 precursor [Homo sapiens] 60 2e-08
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 59 4e-08
gi|239757861 PREDICTED: similar to armadillo repeat containing, ... 56 3e-07
gi|148833508 notch1 preproprotein [Homo sapiens] 55 6e-07
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 54 1e-06
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 54 1e-06
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 54 1e-06
gi|18644886 forkhead box P1 isoform 1 [Homo sapiens] 54 1e-06
gi|62953127 polyhomeotic 1-like [Homo sapiens] 54 2e-06
gi|109255251 loricrin [Homo sapiens] 53 3e-06
gi|221139761 zinc finger protein 853 [Homo sapiens] 52 4e-06
gi|33286444 mastermind-like 2 [Homo sapiens] 52 4e-06
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 52 4e-06
gi|48762934 alpha 2 type I collagen [Homo sapiens] 52 7e-06
>gi|217416332 trinucleotide repeat containing 6C isoform 1 [Homo
sapiens]
Length = 1726
Score = 3576 bits (9273), Expect = 0.0
Identities = 1726/1726 (100%), Positives = 1726/1726 (100%)
Query: 1 MATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSS 60
MATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSS
Sbjct: 1 MATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSS 60
Query: 61 GLAHCSVSGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVAT 120
GLAHCSVSGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVAT
Sbjct: 61 GLAHCSVSGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVAT 120
Query: 121 GNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLN 180
GNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLN
Sbjct: 121 GNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLN 180
Query: 181 TDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGS 240
TDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGS
Sbjct: 181 TDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGS 240
Query: 241 AEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDS 300
AEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDS
Sbjct: 241 AEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDS 300
Query: 301 GPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGS 360
GPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGS
Sbjct: 301 GPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGS 360
Query: 361 TGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGSTGREGTGEGR 420
TGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGSTGREGTGEGR
Sbjct: 361 TGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGSTGREGTGEGR 420
Query: 421 RRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWG 480
RRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWG
Sbjct: 421 RRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWG 480
Query: 481 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDS 540
CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDS
Sbjct: 481 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDS 540
Query: 541 ISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWA 600
ISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWA
Sbjct: 541 ISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWA 600
Query: 601 DSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLK 660
DSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLK
Sbjct: 601 DSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLK 660
Query: 661 PGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRR 720
PGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRR
Sbjct: 661 PGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRR 720
Query: 721 KMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPP 780
KMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPP
Sbjct: 721 KMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPP 780
Query: 781 HQAGTQLNRSPLLGPVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSG 840
HQAGTQLNRSPLLGPVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSG
Sbjct: 781 HQAGTQLNRSPLLGPVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSG 840
Query: 841 WGDHPAEPPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNN 900
WGDHPAEPPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNN
Sbjct: 841 WGDHPAEPPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNN 900
Query: 901 AASQESTSSCSSWGNAPKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPREPAEEALKS 960
AASQESTSSCSSWGNAPKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPREPAEEALKS
Sbjct: 901 AASQESTSSCSSWGNAPKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPREPAEEALKS 960
Query: 961 NNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPLGCRPPISKESSVDRPTFLDKDGG 1020
NNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPLGCRPPISKESSVDRPTFLDKDGG
Sbjct: 961 NNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPLGCRPPISKESSVDRPTFLDKDGG 1020
Query: 1021 LVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFGNSG 1080
LVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFGNSG
Sbjct: 1021 LVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFGNSG 1080
Query: 1081 AAQARTMQQPPQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPI 1140
AAQARTMQQPPQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPI
Sbjct: 1081 AAQARTMQQPPQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPI 1140
Query: 1141 NPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQQHQ 1200
NPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQQHQ
Sbjct: 1141 NPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQQHQ 1200
Query: 1201 RQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFA 1260
RQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFA
Sbjct: 1201 RQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFA 1260
Query: 1261 PYPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKH 1320
PYPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKH
Sbjct: 1261 PYPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKH 1320
Query: 1321 GAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSDSDKISNGSSI 1380
GAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSDSDKISNGSSI
Sbjct: 1321 GAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSDSDKISNGSSI 1380
Query: 1381 NWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSGGSSPPSSQ 1440
NWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSGGSSPPSSQ
Sbjct: 1381 NWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSGGSSPPSSQ 1440
Query: 1441 NATLPSSSAWPLSASGYSSSFSSIASAPSVAGKLSDIKSTWSSGPTSHTQASLSHELWKV 1500
NATLPSSSAWPLSASGYSSSFSSIASAPSVAGKLSDIKSTWSSGPTSHTQASLSHELWKV
Sbjct: 1441 NATLPSSSAWPLSASGYSSSFSSIASAPSVAGKLSDIKSTWSSGPTSHTQASLSHELWKV 1500
Query: 1501 PRNSTAPTRPPPGLTNPKPSSTWGASPLGWTSSYSSGSAWSTDTSGRTSSWLVLRNLTPQ 1560
PRNSTAPTRPPPGLTNPKPSSTWGASPLGWTSSYSSGSAWSTDTSGRTSSWLVLRNLTPQ
Sbjct: 1501 PRNSTAPTRPPPGLTNPKPSSTWGASPLGWTSSYSSGSAWSTDTSGRTSSWLVLRNLTPQ 1560
Query: 1561 IDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKAQKSLHMCVLGNTTILAEFA 1620
IDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKAQKSLHMCVLGNTTILAEFA
Sbjct: 1561 IDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKAQKSLHMCVLGNTTILAEFA 1620
Query: 1621 GEEEVNRFLAQGQALPPTSSWQSSSASSQPRLSAAGSSHGLVRSDAGHWNAPCLGGKGSS 1680
GEEEVNRFLAQGQALPPTSSWQSSSASSQPRLSAAGSSHGLVRSDAGHWNAPCLGGKGSS
Sbjct: 1621 GEEEVNRFLAQGQALPPTSSWQSSSASSQPRLSAAGSSHGLVRSDAGHWNAPCLGGKGSS 1680
Query: 1681 ELLWGGVPQYSSSLWGPPSADDSRVIGSPTPLTTLLPGDLLSGESL 1726
ELLWGGVPQYSSSLWGPPSADDSRVIGSPTPLTTLLPGDLLSGESL
Sbjct: 1681 ELLWGGVPQYSSSLWGPPSADDSRVIGSPTPLTTLLPGDLLSGESL 1726
>gi|33413425 trinucleotide repeat containing 6C isoform 2 [Homo
sapiens]
Length = 1690
Score = 3458 bits (8966), Expect = 0.0
Identities = 1680/1729 (97%), Positives = 1682/1729 (97%), Gaps = 42/1729 (2%)
Query: 1 MATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSS 60
MATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSS
Sbjct: 1 MATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSS 60
Query: 61 GLAHCSVSGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVAT 120
GLAHCSVSGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVAT
Sbjct: 61 GLAHCSVSGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVAT 120
Query: 121 GNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLN 180
GNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLN
Sbjct: 121 GNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLN 180
Query: 181 TDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGS 240
TDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGS
Sbjct: 181 TDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGS 240
Query: 241 AEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDS 300
AEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDS
Sbjct: 241 AEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDS 300
Query: 301 GPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGS 360
GPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGS
Sbjct: 301 GPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGS 360
Query: 361 TGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGSTGREGTGEGR 420
TGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGSTGREGTGEGR
Sbjct: 361 TGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGSTGREGTGEGR 420
Query: 421 RRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWG 480
RRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWG
Sbjct: 421 RRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWG 480
Query: 481 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDS 540
CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDS
Sbjct: 481 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDS 540
Query: 541 ISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWA 600
ISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWA
Sbjct: 541 ISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWA 600
Query: 601 DSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLK 660
DSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLK
Sbjct: 601 DSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLK 660
Query: 661 PGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRR 720
PGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRR
Sbjct: 661 PGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRR 720
Query: 721 KMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPP 780
KMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPP
Sbjct: 721 KMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPP 780
Query: 781 HQAGTQLNRSPLLGP---VSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSS 837
HQAGTQLNRSPLLGP VSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSS
Sbjct: 781 HQAGTQLNRSPLLGPGRKVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSS 840
Query: 838 GSGWGDHPAEPPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDV 897
GSGWGDHPAEPPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDV
Sbjct: 841 GSGWGDHPAEPPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDV 900
Query: 898 WNNAASQESTSSCSSWGNAPKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPREPAEEA 957
WNNAASQESTSSCSSWGNAPKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPREPAEEA
Sbjct: 901 WNNAASQESTSSCSSWGNAPKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPREPAEEA 960
Query: 958 LKSNNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPLGCRPPISKESSVDRPTFLDK 1017
LKSNNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPLGCRPPISKESSVDRPTFLDK
Sbjct: 961 LKSNNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPLGCRPPISKESSVDRPTFLDK 1020
Query: 1018 DGGLVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFG 1077
DGGLVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFG
Sbjct: 1021 DGGLVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFG 1080
Query: 1078 NSGAAQARTMQQPPQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLT 1137
NSGAAQARTMQQPPQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLT
Sbjct: 1081 NSGAAQARTMQQPPQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLT 1140
Query: 1138 SPINPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQ 1197
SPINPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQ
Sbjct: 1141 SPINPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQ 1200
Query: 1198 QHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPN 1257
QHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPN
Sbjct: 1201 QHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPN 1260
Query: 1258 TFAPYPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNP 1317
TFAPYPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNP
Sbjct: 1261 TFAPYPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNP 1320
Query: 1318 SKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSDSDKISNG 1377
SKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSDSDKISNG
Sbjct: 1321 SKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSDSDKISNG 1380
Query: 1378 SSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSGGSSPP 1437
SSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSGG
Sbjct: 1381 SSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSGG---- 1436
Query: 1438 SSQNATLPSSSAWPLSASGYSSSFSSIASAPSVAGKLSDIKSTWSSGPTSHTQASLSHEL 1497
S S++SS GPTSHTQASLSHEL
Sbjct: 1437 ---------------KLSDIKSTWSS--------------------GPTSHTQASLSHEL 1461
Query: 1498 WKVPRNSTAPTRPPPGLTNPKPSSTWGASPLGWTSSYSSGSAWSTDTSGRTSSWLVLRNL 1557
WKVPRNSTAPTRPPPGLTNPKPSSTWGASPLGWTSSYSSGSAWSTDTSGRTSSWLVLRNL
Sbjct: 1462 WKVPRNSTAPTRPPPGLTNPKPSSTWGASPLGWTSSYSSGSAWSTDTSGRTSSWLVLRNL 1521
Query: 1558 TPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKAQKSLHMCVLGNTTILA 1617
TPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKAQKSLHMCVLGNTTILA
Sbjct: 1522 TPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKAQKSLHMCVLGNTTILA 1581
Query: 1618 EFAGEEEVNRFLAQGQALPPTSSWQSSSASSQPRLSAAGSSHGLVRSDAGHWNAPCLGGK 1677
EFAGEEEVNRFLAQGQALPPTSSWQSSSASSQPRLSAAGSSHGLVRSDAGHWNAPCLGGK
Sbjct: 1582 EFAGEEEVNRFLAQGQALPPTSSWQSSSASSQPRLSAAGSSHGLVRSDAGHWNAPCLGGK 1641
Query: 1678 GSSELLWGGVPQYSSSLWGPPSADDSRVIGSPTPLTTLLPGDLLSGESL 1726
GSSELLWGGVPQYSSSLWGPPSADDSRVIGSPTPLTTLLPGDLLSGESL
Sbjct: 1642 GSSELLWGGVPQYSSSLWGPPSADDSRVIGSPTPLTTLLPGDLLSGESL 1690
>gi|116805348 trinucleotide repeat containing 6A [Homo sapiens]
Length = 1962
Score = 1207 bits (3124), Expect = 0.0
Identities = 794/1816 (43%), Positives = 1012/1816 (55%), Gaps = 222/1816 (12%)
Query: 1 MATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSS 60
MA+G+ G G + + G N +V S SN +GS+ WG + G+
Sbjct: 271 MASGNTGGEKDG-LRNSTGLGSQNKFVVGSSSNNVG--------HGSSTGPWGFSHGAII 321
Query: 61 GLAHCSVSGGDGKMDTMIGDGRSQNCWG--ASNSNAGINLN-LNPNANPAAWPVLGHEGT 117
SV + K ++ N WG +S+SN G+N + LN +N AWPVL + G
Sbjct: 322 STCQVSVDAPESKSES---SNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGL 378
Query: 118 VATGNPSSICSPV----SAIGQNMGNQNGNPT----GTLGAWGNLLPQESTEPQTSTSQN 169
G S S + S IGQ NQ+ N T G WG+L QE+ E + S +Q
Sbjct: 379 ALKGPVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTWGSL--QETCESEVSGTQK 436
Query: 170 VSFSAQPQNLNTD--GPNNT-NPMNSSPNPINAMQTNGLPNWGM-AVGMGAIIPPHLQGL 225
VSFS QPQN+ T+ GPNNT N M SS ++Q N LP+ A + + P +Q
Sbjct: 437 VSFSGQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAP 496
Query: 226 PGANGSSVSQVSGGSAE--GISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQ-N 282
G NG+S+S +S G ++ G + WG N + + Q NGDTVN+ L N
Sbjct: 497 SGMNGTSLSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNATLMQPGVN 556
Query: 283 G--SSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVN 340
G ++ GG W+SG A +WG G+G N G+ WG P+++T +
Sbjct: 557 GPMGTNFQVNTNKGGGVWESGA-ANSQSTSWGSGNGANSGGSRRG--WGTPAQNTGTNLP 613
Query: 341 G-EWGK-PPNQHSNSDINGKGST---GWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTA 395
EW K P NQHSN NG G T GW+S Q E + WAK + GT
Sbjct: 614 SVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAK--TGGTVE 671
Query: 396 SEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQ---LPRNDLDPRVLSNTGWGQT 452
S+GS++ +G E +GTGE + RD+ IDQ + + R DLDPRVLSN+GWGQT
Sbjct: 672 SDGSTESTGRLEE-----KGTGESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQT 726
Query: 453 PVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNA 512
P+KQNTAW+ E SPR ERK DNGTEAWG +ATQ NSG D + N +TSSVSGW +
Sbjct: 727 PIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACIDKTSPNGNDTSSVSGWGDP 786
Query: 513 PPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWG 572
PA WGDS K + G W D S A + W N +++ W
Sbjct: 787 KPAL-----RWGDS--KGSNCQGGWEDD------SAATGMVKSNQWG---NCKEEKAAWN 830
Query: 573 EPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWND 632
+ K K Q WGDGQ+S+ WS D +S H G+ K S +DS+RS SGWN+
Sbjct: 831 DSQKNK-QGWGDGQKSSQGWSVSASDNWGETSRNNHWGEANKKSSSGGSDSDRSVSGWNE 889
Query: 633 TTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGA---------- 682
++ + WGN+ N N + W E+ KP P Q W P+ N WG +
Sbjct: 890 LGKTSSFTWGNNINP--NNSSGWDESSKPTPSQGWGDPPKSNQSLGWGDSSKPVSSPDWN 947
Query: 683 -------------ASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTS 729
A+ K GTGW+GGP+P K+ E TGWEEPSP SIRRKMEIDDGTS
Sbjct: 948 KQQDIVGSWGIPPATGKPPGTGWLGGPIPAPAKEE-EPTGWEEPSPESIRRKMEIDDGTS 1006
Query: 730 AWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNR 789
AWGDPS YN K VNMW++N P S + H++ TP A N+
Sbjct: 1007 AWGDPSKYNYKNVNMWNKNVPNGNSRSDQQAQV----------HQLLTP----ASAISNK 1052
Query: 790 SPLLGPVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPP 849
G SGWGE WGEPS+P+T VDNGT+AWGKP SG WG+ A
Sbjct: 1053 EASSG---SGWGE----------PWGEPSTPATTVDNGTSAWGKPIDSGPSWGEPIAAAS 1099
Query: 850 VAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQ---WEDEEG---DVWNNAAS 903
+ V AL K KSMQ+GW GD+M L ++ WE+EE +WN+ +S
Sbjct: 1100 STSTWGSSSVGPQALSKSGPKSMQDGWC--GDDMPLPGNRPTGWEEEEDVEIGMWNSNSS 1157
Query: 904 QESTSSCSSWGNAPKKGLQKG------------MKTSGKQDEAWIMSRLIKQLTDMGFPR 951
QE SS + W KK KG MK KQ+EAWI + +KQ +++ F R
Sbjct: 1158 QELNSSLN-WPPYTKKMSSKGLSGKKRRRERGMMKGGNKQEEAWI-NPFVKQFSNISFSR 1215
Query: 952 EPAEEALKSNNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPLGCRPPISKESSVDR 1011
+ EE ++SN M+L M L +K++++DK L + D+N K G RP ISKESS++R
Sbjct: 1216 DSPEENVQSNKMDLSGGM--LQDKRMEIDKHSLNIGDYNRTVGKGPGSRPQISKESSMER 1273
Query: 1012 PTFLDKDGGLVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSG 1071
+ DKDG + +E F+ S S+KLP S+SALP+QALG IA GLGMQNLNS RQ +G
Sbjct: 1274 NPYFDKDGIVADESQNMQFMSSQSMKLPPSNSALPNQALGSIA-GLGMQNLNSVRQ--NG 1330
Query: 1072 NLGMFG-NSGAAQARTMQQPPQPPVQPLNSSQPSLRAQVPQ-FLSPQVQAQLLQFAAKNI 1129
N MFG + AAQ R MQQPP QPL+SSQP+LRAQVP LSPQV LL++A N
Sbjct: 1331 NPSMFGVGNTAAQPRGMQQPP---AQPLSSSQPNLRAQVPPPLLSPQVPVSLLKYAPNNG 1387
Query: 1130 GLNPALLTSPINPQHMTMLNQLYQL-QLAY----QRLQIQQQMLQAQRNVSGSMRQQEQQ 1184
GLNP PQ + MLNQL QL QL+ QRL QQQ Q+QR+V R Q+ Q
Sbjct: 1388 GLNPLF-----GPQQVAMLNQLSQLNQLSQISQLQRLLAQQQRAQSQRSVPSGNRPQQDQ 1442
Query: 1185 VARTITNLQQQIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGL 1244
R ++ +QQQ+ Q RQL LLVKQ PP LH A KS +D+ H
Sbjct: 1443 QGRPLS-VQQQMMQQSRQLDPNLLVKQQTPPSQQQ--PLHQPAMKSFLDNVMPHTT---- 1495
Query: 1245 PDLQTKEQQSSPNTFAPYPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMD 1304
P+LQ + S N F+ +P+ GLN N+NVN MDM S+K+P QSRL +WT +S+
Sbjct: 1496 PELQ--KGPSPINAFSNFPI-GLNSNLNVN-MDMN---SIKEP---QSRLRKWTTVDSI- 1544
Query: 1305 NLPSAASPLEQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSW 1364
S + L+QN SKHGAI G + + + YD + +S SPASPP ++ W
Sbjct: 1545 ---SVNTSLDQNSSKHGAISSGFRLE-------ESPFVPYDFMNSSTSPASPPGSIGDGW 1594
Query: 1365 SRAKSDSDKISNGSSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDV 1424
RAKS + SS+NWPPEF PG PWKG NIDPE DP VTPGSV +INT +++V
Sbjct: 1595 PRAKSPN----GSSSVNWPPEFRPGEPWKGYPNIDPETDPYVTPGSVINNLSINT-VREV 1649
Query: 1425 NRYLLKSGGSSPPSSQNATLPSSSAWP-LSASGYSSSFSSIASAPSVAGKLSDIKSTWSS 1483
+ ++ GSS SS N TLPS+SAW + AS Y+ SS +A S + + SD K TWS
Sbjct: 1650 DHLRDRNSGSS--SSLNTTLPSTSAWSSIRASNYNVPLSS--TAQSTSARNSDSKLTWSP 1705
Query: 1484 GPTSHTQASLSHELWKVP---RNSTAPTRPPPGLTNPKPS-STWGASPL----GWTSS-- 1533
G ++T SL+HELWKVP +N TAP+RPPPGLT KP STW SPL GW +S
Sbjct: 1706 GSVTNT--SLAHELWKVPLPPKNITAPSRPPPGLTGQKPPLSTWDNSPLRIGGGWGNSDA 1763
Query: 1534 -YSSGSAWSTDTSGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRY 1592
Y+ GS+W +SGR ++WLVL+NLTPQIDGSTLRTLC+QHGPLITFHLNL GNA+VRY
Sbjct: 1764 RYTPGSSWGESSSGRITNWLVLKNLTPQIDGSTLRTLCMQHGPLITFHLNLPHGNALVRY 1823
Query: 1593 SSKEEAAKAQKSLHMCVLGNTTILAEFAGEEEVNRFLAQGQALPPTSSWQSSSASSQPRL 1652
SSKEE KAQKSLHMCVLGNTTILAEFA EEE++RF AQ Q+L P+ WQ S SSQ RL
Sbjct: 1824 SSKEEVVKAQKSLHMCVLGNTTILAEFASEEEISRFFAQSQSLTPSPGWQ-SLGSSQSRL 1882
Query: 1653 SAAGSSHGL-VRSDAGHWNAPCLGGKGSSEL----LWGGVPQYSSSLWGPPSADDSRVIG 1707
+ SH R+D HWN L G +L LW G P YS+SLWGPPS+ D R I
Sbjct: 1883 GSLDCSHSFSSRTDLNHWNGAGLSGTNCGDLHGTSLW-GTPHYSTSLWGPPSSSDPRGIS 1941
Query: 1708 SPTPLTTLLPGDLLSG 1723
SP+P+ L D L G
Sbjct: 1942 SPSPINAFLSVDHLGG 1957
>gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo
sapiens]
Length = 1833
Score = 920 bits (2378), Expect = 0.0
Identities = 686/1820 (37%), Positives = 887/1820 (48%), Gaps = 305/1820 (16%)
Query: 14 TKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGLAHC-------S 66
T+ ++ N N + S +S L ++ G ++ ++G+ L S
Sbjct: 208 TESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKS 267
Query: 67 VSGGDGKMDTMIGDGRSQNCWGASNSNAGINL-NLNPNANPAAWPVLGHEGTVATG---- 121
V + + G G +N G G N NPN+NP+AWP L EGT G
Sbjct: 268 VQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALET 327
Query: 122 NPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLNT 181
+ S+ + VS +GQ Q +S + VS Q Q NT
Sbjct: 328 DNSNSSAQVSTVGQTSREQ-----------------QSKMENAGVNFVVSGREQAQIHNT 370
Query: 182 DGPNN--TNPMN-SSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSG 238
DGP N TN +N SSPNP+ N GM GMG G + + SQ +G
Sbjct: 371 DGPKNGNTNSLNLSSPNPME--------NKGMPFGMGL-------GNTSRSTDAPSQSTG 415
Query: 239 GSAEGISNSVWGLSPGNPAT----GNSNSGFSQGNG----DTVNSALSAKQNGSS--SAV 288
G S WG + G T G SNSG + NG D+ A K GS S
Sbjct: 416 DRKTGSVGS-WGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWD 474
Query: 289 QKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKP-- 346
S G +W+ GP WG G N + G W P+ S + GEW P
Sbjct: 475 NNNRSTGGSWNFGPQDSNDN-KWGEG--NKMTSGVSQGEWKQPTGSDELKI-GEWSGPNQ 530
Query: 347 PNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNH 406
PN + + N KG P +Q P W +++SS + G S GS NH
Sbjct: 531 PNSSTGAWDNQKGH-----PLPENQGNAQAP------CWGRSSSSTGSEVGGQSTGS-NH 578
Query: 407 NEGSTGREGTGEGRRRDKGIIDQGHIQ--LPRNDLDPRVLSNTGWGQTPVKQNTAWEFEE 464
GS+ +G R Q +Q L R DLDPRVLSNTGWGQT +KQ+T W+ EE
Sbjct: 579 KAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEE 638
Query: 465 SPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWG 524
PR E K+D GTE W AATQ NSGG D S + SGW + A+T W
Sbjct: 639 VPRPEGKSDKGTEGWESAATQTKNSGGWGDAP---SQSNQMKSGW-----GELSASTEWK 690
Query: 525 DSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGD 584
D P G W D ++ + + W G E +W E P K Q WG
Sbjct: 691 D-----PKNTGGWNDYKNNNSSN----------WGGGRPDEKTPSSWNENPS-KDQGWGG 734
Query: 585 GQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNS 644
G++ N WS+G W + D KN S W++ +++ SGW + ++ WGN
Sbjct: 735 GRQPNQGWSSGKNGWGEEV-------DQTKN-SNWESSASKPVSGWGEGGQNEIGTWGNG 786
Query: 645 TNTKANPGTNWGETLKPGPQQNWASK--------------------PQDNNVSNWGGA-- 682
N W E K P N + PQ +WGG
Sbjct: 787 GNASLASKGGW-EDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPP 845
Query: 683 ---ASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNN 739
+V+ + + W GP P KD E +GWEEPSP SI RKM+IDDGTSAWGDP++YN
Sbjct: 846 PPPGNVRPSNSSWSSGPQPATPKDE-EPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNY 904
Query: 740 KTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPVSSG 799
K VN+WD+N+ + N T T
Sbjct: 905 KNVNLWDKNSQGGPAPREPNLPTPMT---------------------------------- 930
Query: 800 WGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPV 859
SK+ + W + + P+ DNGT+AWG+P S GWG+ G P
Sbjct: 931 --------SKSASVWSKSTPPAP--DNGTSAWGEPNESSPGWGEMDDTGASTTGWGNTPA 980
Query: 860 AASALCKPASKSMQEGWG-SGGDEMNLSTSQWEDEE-GDVWNNAASQESTSS--CSSWGN 915
A KP SKSMQ+GWG S G WE+EE G VWN SQ S SS +SWG
Sbjct: 981 NAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQ 1040
Query: 916 APKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPREPAEEALKSNNMNLDQAMSALLEK 975
KK ++ +K G +++W M+ L KQ ++MG + + + +D ++ +L +K
Sbjct: 1041 GGKKQMKCSLK--GGNNDSW-MNPLAKQFSNMGLLSQTEDNP----SSKMDLSVGSLSDK 1093
Query: 976 KVDVDKRGLGVTDHNGMAAKPL-GCRPPISKE-SSVDRPTFLDK--------DGGLVEEP 1025
K DVDKR + + D N + K G RPP SK+ + D + +K DG L +E
Sbjct: 1094 KFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKLTLPFSNQDGCLGDEA 1153
Query: 1026 TPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFGNSGAAQAR 1085
SPF PSPS KL S S LP+ +LG I +GL QN ++RQ G+ G+FGNS AQ+R
Sbjct: 1154 PCSPFSPSPSYKLSPSGSTLPNVSLGAIGTGLNPQNF-AARQ--GGSHGLFGNS-TAQSR 1209
Query: 1086 TMQQPPQPPVQPLNSSQPSLRAQVP-QFLSPQVQAQLLQFAAKNIGLNPALLT--SPINP 1142
+ P VQPLNSS PSLRAQVP QF+SPQV A +L+ N GL+P L ++P
Sbjct: 1210 GLHTP----VQPLNSS-PSLRAQVPPQFISPQVSASMLK-QFPNSGLSPGLFNVGPQLSP 1263
Query: 1143 QHMTMLNQLYQL---QLAYQRL---QIQQQMLQAQRNVSGSMRQQ-EQQVARTITNLQQQ 1195
Q + ML+QL Q+ QLA Q L Q QQQ+LQ QR +S ++RQQ EQQ+AR ++ LQQQ
Sbjct: 1264 QQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQ 1323
Query: 1196 IQQHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSS 1255
QQ QRQ P H HP K +D+ + GLPDLQTK
Sbjct: 1324 QQQQQRQ-------------PGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKG---- 1366
Query: 1256 PNTFAPYPLAGLNPNMNVNSMD--MTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPL 1313
P+ G + MD M GG + ++SR QWT + M+ LPS A+
Sbjct: 1367 -------PIPGYGSGFSSGGMDYGMVGGKE----AGTESRFKQWT--SMMEGLPSVATQ- 1412
Query: 1314 EQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSD-SD 1372
E N K+GAI PGK+ Y ++D+I A SW AKS ++
Sbjct: 1413 EANMHKNGAIVA------PGKTRGGSPYNQFDIIPGDTLGGHTGPA-GDSWLPAKSPPTN 1465
Query: 1373 KI-SNGSSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKS 1431
KI S S+ +WPPEF PGVPWKG+QNIDPE+DP VTPGSV G T + I D + LL+
Sbjct: 1466 KIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSV-LGGTATSPIVDTDHQLLRD 1524
Query: 1432 GGSSPPSSQNATLPSSSAWPLSASGYSSSFSSIASAPSVAGKLSDIKSTWSSGPTSHTQA 1491
+ SS N +LPS AWP YS+S +S + S + K D KSTWS P H
Sbjct: 1525 NTTGSNSSLNTSLPSPGAWP-----YSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPT 1579
Query: 1492 SLSHELWK---VPRNSTAPTRPPPGLTNPKPSSTWGA----SPLGW---TSSYSSGSAWS 1541
LS+++WK RN+T RPPPGLTNPKPSS W + S GW S +S S WS
Sbjct: 1580 HLSNKMWKNHISSRNTTPLPRPPPGLTNPKPSSPWSSTAPRSVRGWGTQDSRLASASTWS 1639
Query: 1542 TDTSGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKA 1601
S R S WLVL NLTPQIDGSTLRT+C+QHGPL+TFHLNLTQG A++RYS+K+EAAKA
Sbjct: 1640 DGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKA 1699
Query: 1602 QKSLHMCVLGNTTILAEFAGEEEVNRFLAQGQ-----ALP--PTSSWQSSSASSQ----- 1649
Q +LHMCVLGNTTILAEFA ++EV+RFLAQ Q A P P + WQS
Sbjct: 1700 QTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPV 1759
Query: 1650 -PRLSAAGSSHGLVRSDAGHWNAPCLGGKG---SSELLWGGVPQYSSSLWGPPSADDSRV 1705
P L+ G S GL G W++ G G + LW G P YSSSLWG P+ +D
Sbjct: 1760 GPALNLFGGSTGL-----GQWSSSAGGSSGADLAGASLW-GPPNYSSSLWGVPTVEDPHR 1813
Query: 1706 IGSPTPLTTLLPGDLLSGES 1725
+GSP P LLPGDLL G S
Sbjct: 1814 MGSPAP---LLPGDLLGGGS 1830
Score = 43.9 bits (102), Expect = 0.001
Identities = 96/497 (19%), Positives = 178/497 (35%), Gaps = 86/497 (17%)
Query: 481 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWG----DSNNKAPSGPGV 536
C A A+ + + G+++ S + ++ + A+ AN+ WG +N +P+ +
Sbjct: 127 CTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHI 186
Query: 537 WGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSA-- 594
W I W A+++ +S + + + G + + P +
Sbjct: 187 WDKVI--------VDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSN 238
Query: 595 -GGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKA---- 649
G G S+S + N W +D +++T N+G GN N
Sbjct: 239 KGKGSQCQSAS-----SGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRI 293
Query: 650 ---------NPGTN---WGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPV 697
NP +N W ++ G + A + ++N S ++V QT
Sbjct: 294 GPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSS--AQVSTVGQTSR------- 344
Query: 698 PVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRN---NPVIQS 754
+Q+ E G + ++ DG P N N ++N+ N N +
Sbjct: 345 --EQQSKMENAGVNFVVSGREQAQIHNTDG------PKNGNTNSLNLSSPNPMENKGMPF 396
Query: 755 STTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPVSSGW---GEMPNVHSKTE 811
T+ +T S +T +T G R P SG G N + E
Sbjct: 397 GMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAA--RGPSGTDTVSGQSNSGNNGNNGKERE 454
Query: 812 NSW-GEPSSPSTLVDN-----------GTAAWGKPPSSGSGWGD-HPAEPPVAFGRAGAP 858
+SW G ST N G+ +G S+ + WG+ + V+ G P
Sbjct: 455 DSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQP 514
Query: 859 VAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWG-NAP 917
S ++ G SG ++ N ST W++++G + + + WG ++
Sbjct: 515 T--------GSDELKIGEWSGPNQPNSSTGAWDNQKG---HPLPENQGNAQAPCWGRSSS 563
Query: 918 KKGLQKGMKTSGKQDEA 934
G + G +++G +A
Sbjct: 564 STGSEVGGQSTGSNHKA 580
>gi|148491080 trinucleotide repeat containing 6B isoform 2 [Homo
sapiens]
Length = 1723
Score = 652 bits (1682), Expect = 0.0
Identities = 592/1826 (32%), Positives = 814/1826 (44%), Gaps = 356/1826 (19%)
Query: 18 NGNNG-TNGALVQSPSNQSALGA-GGANSNGSAARVWGVATGSSSGLAHCSVSGGDGKMD 75
N NN GAL+QS S + GGA ++ A WG S++G + + D
Sbjct: 133 NPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIH----IWD 188
Query: 76 TMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVATGNPSSICSPVSAIGQ 135
+I DG W S + + N N +A + G+ + P S S Q
Sbjct: 189 KVIVDGSDMEEWPCIASKDTESSSENTTDNNSA----SNPGSEKSTLPGSTTSNKGKGSQ 244
Query: 136 NMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLNTD-------GPNNTN 188
+GN LG W + +S + ST++N + +N++ G +N N
Sbjct: 245 CQSASSGNECN-LGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFN 303
Query: 189 PMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVS--GGSAEGISN 246
P NS+P+ A+ G G L N +S +QVS G ++ +
Sbjct: 304 P-NSNPSAWPALVQEGTSRKG--------------ALETDNSNSSAQVSTVGQTSREQQS 348
Query: 247 SVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPPAGP 306
+ +G + +G +NG+++++ N P
Sbjct: 349 KMENAGVNFVVSGREQAQIHNTDGP---------KNGNTNSL-------NLSSPNPMENK 392
Query: 307 GILAWGRGSGNNGVGNIHSGAWGHPSRSTSN---GVNGEWGKPPNQHSNSDINGKGSTGW 363
G + +G G GN S + PS+ST + G G WG ++G+ ++G
Sbjct: 393 G-MPFGMGLGNT------SRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGN 445
Query: 364 ESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGSTGREGT------- 416
+ G E +SW A+ +T S+ S + N + G + G
Sbjct: 446 NGNN----------GKEREDSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNK 495
Query: 417 -GEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEES-PRSERKNDN 474
GEG + G+ QG + P + ++ +G Q P AW+ ++ P E + +
Sbjct: 496 WGEGNKMTSGV-SQGEWKQPTGSDELKIGEWSGPNQ-PNSSTGAWDNQKGHPLPENQGNA 553
Query: 475 GTEAWG-CAATQASNSGGKNDGSIMNSTNTSSV-SGWVNAPPA----------------- 515
WG +++ S GG++ GS + ++ S SG + P
Sbjct: 554 QAPCWGRSSSSTGSEVGGQSTGSNHKAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDL 613
Query: 516 --AVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGE 573
V +NTGWG + K + VW I + K W AA Q S WG+
Sbjct: 614 DPRVLSNTGWGQTQIKQDT---VW--DIEEVPRPEGKSDKGTEGWESAATQTKNSGGWGD 668
Query: 574 PPKPKSQH---WGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDAD--SNRSGS 628
P +Q WG+ S +W D + G N S W ++ S
Sbjct: 669 APSQSNQMKSGWGELSAST--------EWKDPKNTGGWNDYKNNNSSNWGGGRPDEKTPS 720
Query: 629 GWNDTTRSGNSGWGNST--NTKANPGTN-WGETLKPGPQQNW---ASKPQDNNVSNWGGA 682
WN+ S + GWG N + G N WGE + NW ASKP VS WG
Sbjct: 721 SWNENP-SKDQGWGGGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKP----VSGWGEG 775
Query: 683 ASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTV 742
+ GT GG + K GWE+ + AW N +
Sbjct: 776 GQ-NEIGTWGNGGNASLASKG-----GWEDCKR------------SPAW----NETGRQP 813
Query: 743 NMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPVSSGWGE 802
N W++ + Q S + PPP + P +S W
Sbjct: 814 NSWNKQH---QQQQPPQQPPPPQPEASGSWGGPPPPPPGN----------VRPSNSSWSS 860
Query: 803 MPNVHSKTE---NSWGEPSSPSTL----VDNGTAAWGKPPS----------SGSGWGDHP 845
P + + + W EPS S +D+GT+AWG P S S G P
Sbjct: 861 GPQPATPKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAP 920
Query: 846 AEPPVAFGRAGAPVAASALCKPASKSMQEGWG-SGGDEMNLSTSQWEDEE-GDVWNNAAS 903
EP + P ++ SKSMQ+GWG S G WE+EE G VWN S
Sbjct: 921 REPNL-------PTPMTSKSASDSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGS 973
Query: 904 QESTSS--CSSWGNAPKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPREPAEEALKSN 961
Q S SS +SWG KK ++ +K G +++W M+ L KQ ++MG + +
Sbjct: 974 QGSASSHNSASWGQGGKKQMKCSLK--GGNNDSW-MNPLAKQFSNMGLLSQTEDNP---- 1026
Query: 962 NMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKP-LGCRPPISKE-SSVDRPTFLDKDG 1019
+ +D ++ +L +KK DVDKR + + D N + K G RPP SK+ + D + +K G
Sbjct: 1027 SSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKGG 1086
Query: 1020 GLVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFGNS 1079
SH G+FGNS
Sbjct: 1087 ---------------------SH-------------------------------GLFGNS 1094
Query: 1080 GAAQARTMQQPPQPPVQPLNSSQPSLRAQV-PQFLSPQVQAQLLQFAAKNIGLNPALLT- 1137
AQ+R + PVQPLNSS PSLRAQV PQF+SPQV A +L+ N GL+P L
Sbjct: 1095 -TAQSRGL----HTPVQPLNSS-PSLRAQVPPQFISPQVSASMLK-QFPNSGLSPGLFNV 1147
Query: 1138 -SPINPQHMTMLNQLYQL---QLAYQRL---QIQQQMLQAQRNVSGSMR-QQEQQVARTI 1189
++PQ + ML+QL Q+ QLA Q L Q QQQ+LQ QR +S ++R QQEQQ+AR +
Sbjct: 1148 GPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMV 1207
Query: 1190 TNLQQQIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQT 1249
+ LQQQ QQ QRQ P H HP K +D+ + GLPDLQT
Sbjct: 1208 SALQQQQQQQQRQ-------------PGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQT 1254
Query: 1250 KEQQSSPNTFAPYPLAGLNPNMNVNSMD--MTGGLSVKDPSQSQSRLPQWTHPNSMDNLP 1307
K P+ G + MD M GG + ++SR QWT + M+ LP
Sbjct: 1255 KG-----------PIPGYGSGFSSGGMDYGMVGG----KEAGTESRFKQWT--SMMEGLP 1297
Query: 1308 SAASPLEQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRA 1367
S A+ E N K+GAI PGK+ Y ++D+I ++ SW A
Sbjct: 1298 SVATQ-EANMHKNGAIVA------PGKTRGGSPYNQFDIIP-GDTLGGHTGPAGDSWLPA 1349
Query: 1368 KS-DSDKI-SNGSSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVN 1425
KS ++KI S S+ +WPPEF PGVPWKG+QNIDPE+DP VTPGSV G T + I D +
Sbjct: 1350 KSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSV-LGGTATSPIVDTD 1408
Query: 1426 RYLLKSGGSSPPSSQNATLPSSSAWPLSASGYSSSFSSIASAPSVAGKLSDIKSTWSSGP 1485
LL+ + SS N +LPS AWP YS+S +S + S + K D KSTWS P
Sbjct: 1409 HQLLRDNTTGSNSSLNTSLPSPGAWP-----YSASDNSFTNVHSTSAKFPDYKSTWSPDP 1463
Query: 1486 TSHTQASLSHELWK---VPRNSTAPTRPPPGLTNPKPSSTWGA----SPLGW---TSSYS 1535
H LS+++WK RN+T RPPPGLTNPKPSS W + S GW S +
Sbjct: 1464 IGHNPTHLSNKMWKNHISSRNTTPLPRPPPGLTNPKPSSPWSSTAPRSVRGWGTQDSRLA 1523
Query: 1536 SGSAWSTDTSGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSK 1595
S S WS S R S WLVL NLTPQIDGSTLRT+C+QHGPL+TFHLNLTQG A++RYS+K
Sbjct: 1524 SASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTK 1583
Query: 1596 EEAAKAQKSLHMCVLGNTTILAEFAGEEEVNRFLAQGQ-----ALP--PTSSWQSSSASS 1648
+EAAKAQ +LHMCVLGNTTILAEFA ++EV+RFLAQ Q A P P + WQS
Sbjct: 1584 QEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQ 1643
Query: 1649 Q------PRLSAAGSSHGLVRSDAGHWNAPCLGGKG---SSELLWGGVPQYSSSLWGPPS 1699
P L+ G S GL G W++ G G + LW G P YSSSLWG P+
Sbjct: 1644 NQSDPVGPALNLFGGSTGL-----GQWSSSAGGSSGADLAGASLW-GPPNYSSSLWGVPT 1697
Query: 1700 ADDSRVIGSPTPLTTLLPGDLLSGES 1725
+D +GSP P LLPGDLL G S
Sbjct: 1698 VEDPHRMGSPAP---LLPGDLLGGGS 1720
Score = 328 bits (840), Expect = 4e-89
Identities = 269/874 (30%), Positives = 366/874 (41%), Gaps = 148/874 (16%)
Query: 14 TKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGLAHC-------S 66
T+ ++ N N + S +S L ++ G ++ ++G+ L S
Sbjct: 208 TESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKS 267
Query: 67 VSGGDGKMDTMIGDGRSQNCWGASNSNAGINL-NLNPNANPAAWPVLGHEGTVATG---- 121
V + + G G +N G G N NPN+NP+AWP L EGT G
Sbjct: 268 VQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALET 327
Query: 122 NPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLNT 181
+ S+ + VS +GQ Q +S + VS Q Q NT
Sbjct: 328 DNSNSSAQVSTVGQTSREQ-----------------QSKMENAGVNFVVSGREQAQIHNT 370
Query: 182 DGPNN--TNPMN-SSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSG 238
DGP N TN +N SSPNP+ N GM GMG G + + SQ +G
Sbjct: 371 DGPKNGNTNSLNLSSPNPME--------NKGMPFGMGL-------GNTSRSTDAPSQSTG 415
Query: 239 GSAEGISNSVWGLSPGNPAT----GNSNSGFSQGNG----DTVNSALSAKQNGSS--SAV 288
G S WG + G T G SNSG + NG D+ A K GS S
Sbjct: 416 DRKTGSVGS-WGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWD 474
Query: 289 QKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKP-- 346
S G +W+ GP WG G N + G W P+ S + GEW P
Sbjct: 475 NNNRSTGGSWNFGPQDSNDN-KWGEG--NKMTSGVSQGEWKQPTGSDELKI-GEWSGPNQ 530
Query: 347 PNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNH 406
PN + + N KG P +Q P W +++SS + G S GS NH
Sbjct: 531 PNSSTGAWDNQKGH-----PLPENQGNAQAP------CWGRSSSSTGSEVGGQSTGS-NH 578
Query: 407 NEGSTGREGTGEGRRRDKGIIDQGHIQ--LPRNDLDPRVLSNTGWGQTPVKQNTAWEFEE 464
GS+ +G R Q +Q L R DLDPRVLSNTGWGQT +KQ+T W+ EE
Sbjct: 579 KAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEE 638
Query: 465 SPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWG 524
PR E K+D GTE W AATQ NSGG D S + SGW + A+T W
Sbjct: 639 VPRPEGKSDKGTEGWESAATQTKNSGGWGDAP---SQSNQMKSGW-----GELSASTEWK 690
Query: 525 DSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGD 584
D P G W D ++ + + W G E +W E P K Q WG
Sbjct: 691 D-----PKNTGGWNDYKNNNSSN----------WGGGRPDEKTPSSWNENPS-KDQGWGG 734
Query: 585 GQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNS 644
G++ N WS+G W G D KN S W++ +++ SGW + ++ WGN
Sbjct: 735 GRQPNQGWSSGKNGW-------GEEVDQTKN-SNWESSASKPVSGWGEGGQNEIGTWGNG 786
Query: 645 TNTKANPGTNWGETLKPGPQQNWASK--------------------PQDNNVSNWGG--- 681
N W E K P N + PQ +WGG
Sbjct: 787 GNASLASKGGW-EDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPP 845
Query: 682 --AASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNN 739
+V+ + + W GP P KD E +GWEEPSP SI RKM+IDDGTSAWGDP++YN
Sbjct: 846 PPPGNVRPSNSSWSSGPQPATPKD-EEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNY 904
Query: 740 KTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPVSSG 799
K VN+WD+N+ + N T T+ +++ + + Q G + P+ G
Sbjct: 905 KNVNLWDKNSQGGPAPREPNLPTPMTSKSASDSKSM------QDGWGESDGPVTGARHPS 958
Query: 800 WGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGK 833
W E + W S + + +A+WG+
Sbjct: 959 WEE-----EEDGGVWNTTGSQGSASSHNSASWGQ 987
Score = 43.9 bits (102), Expect = 0.001
Identities = 96/497 (19%), Positives = 178/497 (35%), Gaps = 86/497 (17%)
Query: 481 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWG----DSNNKAPSGPGV 536
C A A+ + + G+++ S + ++ + A+ AN+ WG +N +P+ +
Sbjct: 127 CTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHI 186
Query: 537 WGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSA-- 594
W I W A+++ +S + + + G + + P +
Sbjct: 187 WDKVI--------VDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSN 238
Query: 595 -GGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKA---- 649
G G S+S + N W +D +++T N+G GN N
Sbjct: 239 KGKGSQCQSAS-----SGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRI 293
Query: 650 ---------NPGTN---WGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPV 697
NP +N W ++ G + A + ++N S ++V QT
Sbjct: 294 GPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSS--AQVSTVGQTSR------- 344
Query: 698 PVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRN---NPVIQS 754
+Q+ E G + ++ DG P N N ++N+ N N +
Sbjct: 345 --EQQSKMENAGVNFVVSGREQAQIHNTDG------PKNGNTNSLNLSSPNPMENKGMPF 396
Query: 755 STTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPVSSGW---GEMPNVHSKTE 811
T+ +T S +T +T G R P SG G N + E
Sbjct: 397 GMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAA--RGPSGTDTVSGQSNSGNNGNNGKERE 454
Query: 812 NSW-GEPSSPSTLVDN-----------GTAAWGKPPSSGSGWGD-HPAEPPVAFGRAGAP 858
+SW G ST N G+ +G S+ + WG+ + V+ G P
Sbjct: 455 DSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQP 514
Query: 859 VAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWG-NAP 917
S ++ G SG ++ N ST W++++G + + + WG ++
Sbjct: 515 T--------GSDELKIGEWSGPNQPNSSTGAWDNQKG---HPLPENQGNAQAPCWGRSSS 563
Query: 918 KKGLQKGMKTSGKQDEA 934
G + G +++G +A
Sbjct: 564 STGSEVGGQSTGSNHKA 580
Score = 33.1 bits (74), Expect = 2.4
Identities = 64/269 (23%), Positives = 94/269 (34%), Gaps = 38/269 (14%)
Query: 631 NDTTRSGNSGWGN---STNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQ 687
++ T N W N S NT P G T P P W+S +V WG S
Sbjct: 1466 HNPTHLSNKMWKNHISSRNTTPLPRPPPGLT-NPKPSSPWSSTAP-RSVRGWGTQDSRLA 1523
Query: 688 TGTGWI-GGPVP----------VKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSN 736
+ + W GG V Q D S P + + + GT+
Sbjct: 1524 SASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTAL----IR 1579
Query: 737 YNNK--------TVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQL- 787
Y+ K ++M N I + T+ + + TP AG Q
Sbjct: 1580 YSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSL 1639
Query: 788 ----NRSPLLGPVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGD 843
N+S +GP + +G + + ++ G SS + L G + WG P S S WG
Sbjct: 1640 ETGQNQSDPVGPALNLFGGSTGLGQWSSSAGG--SSGADLA--GASLWGPPNYSSSLWGV 1695
Query: 844 HPAEPPVAFGRAGAPVAASALCKPASKSM 872
E P G + AP+ L S S+
Sbjct: 1696 PTVEDPHRMG-SPAPLLPGDLLGGGSDSI 1723
>gi|67782330 trinucleotide repeat containing 6B isoform 3 [Homo
sapiens]
Length = 1029
Score = 573 bits (1476), Expect = e-163
Identities = 410/995 (41%), Positives = 522/995 (52%), Gaps = 175/995 (17%)
Query: 778 PPPHQA-GTQLNRSPLLGPVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPS 836
PPP A G N + + G + S T W + + P+ DNGT+AWG+P
Sbjct: 160 PPPCTAPGANPNNAQVTGALLQS-------ESGTAPVWSKSTPPAP--DNGTSAWGEPNE 210
Query: 837 SGSGWGDHPAEPPVAFGRAGAPVAASALCKPASKSMQEGWG-SGGDEMNLSTSQWEDEE- 894
S GWG+ G P A KP SKSMQ+GWG S G WE+EE
Sbjct: 211 SSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEED 270
Query: 895 GDVWNNAASQESTSS--CSSWGNAPKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPRE 952
G VWN SQ S SS +SWG KK ++ +K G +++W M+ L KQ ++MG +
Sbjct: 271 GGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLK--GGNNDSW-MNPLAKQFSNMGLLSQ 327
Query: 953 PAEEALKSNNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPL-GCRPPISKE-SSVD 1010
+ + +D ++ +L +KK DVDKR + + D N + K G RPP SK+ + D
Sbjct: 328 TEDNP----SSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTD 383
Query: 1011 RPTFLDKDGGLVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPS 1070
+ +K
Sbjct: 384 SGPYFEK----------------------------------------------------G 391
Query: 1071 GNLGMFGNSGAAQARTMQQPPQPPVQPLNSSQPSLRAQVP-QFLSPQVQAQLLQFAAKNI 1129
G+ G+FGNS AQ+R + P VQPLNSS PSLRAQVP QF+SPQV A +L+ N
Sbjct: 392 GSHGLFGNS-TAQSRGLHTP----VQPLNSS-PSLRAQVPPQFISPQVSASMLK-QFPNS 444
Query: 1130 GLNPALLT--SPINPQHMTMLNQLYQL---QLAYQRL---QIQQQMLQAQRNVSGSMRQQ 1181
GL+P L ++PQ + ML+QL Q+ QLA Q L Q QQQ+LQ QR +S ++RQQ
Sbjct: 445 GLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQ 504
Query: 1182 -EQQVARTITNLQQQIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQ 1240
EQQ+AR ++ LQQQ QQ QRQ P H HP K +D+ +
Sbjct: 505 QEQQLARMVSALQQQQQQQQRQ-------------PGMKHSPSHPVGPKPHLDNMVPNAL 551
Query: 1241 TPGLPDLQTKEQQSSPNTFAPYPLAGLNPNMNVNSMD--MTGGLSVKDPSQSQSRLPQWT 1298
GLPDLQTK P+ G + MD M GG + ++SR QWT
Sbjct: 552 NVGLPDLQTKG-----------PIPGYGSGFSSGGMDYGMVGGKE----AGTESRFKQWT 596
Query: 1299 HPNSMDNLPSAASPLEQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPV 1358
+ M+ LPS A+ E N K+GAI PGK+ Y ++D+I
Sbjct: 597 --SMMEGLPSVATQ-EANMHKNGAIVA------PGKTRGGSPYNQFDIIPGDTLGGHTGP 647
Query: 1359 AVPHSWSRAKSD-SDKI-SNGSSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPT 1416
A SW AKS ++KI S S+ +WPPEF PGVPWKG+QNIDPE+DP VTPGSV G T
Sbjct: 648 A-GDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSV-LGGT 705
Query: 1417 INTTIQDVNRYLLKSGGSSPPSSQNATLPSSSAWPLSASGYSSSFSSIASAPSVAGKLSD 1476
+ I D + LL+ + SS N +LPS AWP YS+S +S + S + K D
Sbjct: 706 ATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWP-----YSASDNSFTNVHSTSAKFPD 760
Query: 1477 IKSTWSSGPTSHTQASLSHELWK---VPRNSTAPTRPPPGLTNPKPSSTWGA----SPLG 1529
KSTWS P H LS+++WK RN+T RPPPGLTNPKPSS W + S G
Sbjct: 761 YKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPPPGLTNPKPSSPWSSTAPRSVRG 820
Query: 1530 W---TSSYSSGSAWSTDTSGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQG 1586
W S +S S WS S R S WLVL NLTPQIDGSTLRT+C+QHGPL+TFHLNLTQG
Sbjct: 821 WGTQDSRLASASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQG 880
Query: 1587 NAVVRYSSKEEAAKAQKSLHMCVLGNTTILAEFAGEEEVNRFLAQGQ-----ALP--PTS 1639
A++RYS+K+EAAKAQ +LHMCVLGNTTILAEFA ++EV+RFLAQ Q A P P +
Sbjct: 881 TALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAATPSAPAA 940
Query: 1640 SWQSSSASSQ------PRLSAAGSSHGLVRSDAGHWNAPCLGGKG---SSELLWGGVPQY 1690
WQS P L+ G S GL G W++ G G + LW G P Y
Sbjct: 941 GWQSLETGQNQSDPVGPALNLFGGSTGL-----GQWSSSAGGSSGADLAGASLW-GPPNY 994
Query: 1691 SSSLWGPPSADDSRVIGSPTPLTTLLPGDLLSGES 1725
SSSLWG P+ +D +GSP P LLPGDLL G S
Sbjct: 995 SSSLWGVPTVEDPHRMGSPAP---LLPGDLLGGGS 1026
Score = 41.6 bits (96), Expect = 0.007
Identities = 43/200 (21%), Positives = 68/200 (34%), Gaps = 39/200 (19%)
Query: 481 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDS 540
C A A+ + + G+++ S + ++ + PPA + WG+ N +P WG+
Sbjct: 163 CTAPGANPNNAQVTGALLQSESGTAPVWSKSTPPAPDNGTSAWGEPNESSPG----WGE- 217
Query: 541 ISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWA 600
+ T ST +G N +P P KS G G+ P A W
Sbjct: 218 MDDTGAST----------TGWGNTPANAPN-AMKPNSKSMQDGWGESDGPVTGARHPSW- 265
Query: 601 DSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLK 660
+ G WN T G++ NS + +LK
Sbjct: 266 ---------------------EEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLK 304
Query: 661 PGPQQNWASKPQDNNVSNWG 680
G +W + P SN G
Sbjct: 305 GGNNDSWMN-PLAKQFSNMG 323
Score = 40.0 bits (92), Expect = 0.020
Identities = 55/219 (25%), Positives = 81/219 (36%), Gaps = 55/219 (25%)
Query: 473 DNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAP---PAAVPANT-----GWG 524
DNGT AWG ++S G+ D + +S +GW N P P A+ N+ GWG
Sbjct: 199 DNGTSAWG-EPNESSPGWGEMDDT------GASTTGWGNTPANAPNAMKPNSKSMQDGWG 251
Query: 525 DSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGD 584
+S+ GP ++ + + G W+ +Q G S WG
Sbjct: 252 ESD-----GP------VTGARHPSWEEEEDGGVWNTTGSQ-------GSASSHNSASWGQ 293
Query: 585 GQRSNPAWSAGGGD---W----ADSSSVLGHLGDGKKNGSG-------------WDADSN 624
G + S GG+ W A S +G L + N S +D D
Sbjct: 294 GGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKR 353
Query: 625 RSGSG-WNDTTRSGNSGWGNSTNTKANPGTNWGETLKPG 662
G +ND R SG+ N+K T+ G + G
Sbjct: 354 AMNLGDFNDIMRKDRSGF-RPPNSKDMGTTDSGPYFEKG 391
Score = 38.1 bits (87), Expect = 0.075
Identities = 35/157 (22%), Positives = 55/157 (35%), Gaps = 42/157 (26%)
Query: 284 SSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEW 343
+ + +Q E W P P +NG + AWG P+ S+ W
Sbjct: 176 TGALLQSESGTAPVWSKSTPPAP----------DNG-----TSAWGEPNESSPG-----W 215
Query: 344 GKPPNQHSNSDINGKGSTGWESPSVTSQNP------TVQPG---------GEHMNSWAKA 388
G+ D G +TGW + + N ++Q G G SW +
Sbjct: 216 GE-------MDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEE 268
Query: 389 ASSGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKG 425
G + GS + +HN S G+ G + + KG
Sbjct: 269 EDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKG 305
Score = 37.7 bits (86), Expect = 0.097
Identities = 32/134 (23%), Positives = 54/134 (40%), Gaps = 22/134 (16%)
Query: 701 QKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNT 760
Q +S A W + +PP+ D+GTSAWG+P N++ W + T +
Sbjct: 181 QSESGTAPVWSKSTPPAP------DNGTSAWGEP----NESSPGWG------EMDDTGAS 224
Query: 761 TTTTTTTTSNTTHRVE-TPPPHQAGTQLNRSPLLGPVSSGWGEMPNVHSKTENSWGEPSS 819
TT T +N + ++ Q G + P+ G W E + W S
Sbjct: 225 TTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEE-----EEDGGVWNTTGS 279
Query: 820 PSTLVDNGTAAWGK 833
+ + +A+WG+
Sbjct: 280 QGSASSHNSASWGQ 293
Score = 33.1 bits (74), Expect = 2.4
Identities = 64/269 (23%), Positives = 94/269 (34%), Gaps = 38/269 (14%)
Query: 631 NDTTRSGNSGWGN---STNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQ 687
++ T N W N S NT P G T P P W+S +V WG S
Sbjct: 772 HNPTHLSNKMWKNHISSRNTTPLPRPPPGLT-NPKPSSPWSSTAP-RSVRGWGTQDSRLA 829
Query: 688 TGTGWI-GGPVP----------VKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSN 736
+ + W GG V Q D S P + + + GT+
Sbjct: 830 SASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTAL----IR 885
Query: 737 YNNK--------TVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQL- 787
Y+ K ++M N I + T+ + + TP AG Q
Sbjct: 886 YSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSL 945
Query: 788 ----NRSPLLGPVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGD 843
N+S +GP + +G + + ++ G SS + L G + WG P S S WG
Sbjct: 946 ETGQNQSDPVGPALNLFGGSTGLGQWSSSAGG--SSGADLA--GASLWGPPNYSSSLWGV 1001
Query: 844 HPAEPPVAFGRAGAPVAASALCKPASKSM 872
E P G + AP+ L S S+
Sbjct: 1002 PTVEDPHRMG-SPAPLLPGDLLGGGSDSI 1029
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 105 bits (261), Expect = 5e-22
Identities = 200/965 (20%), Positives = 333/965 (34%), Gaps = 102/965 (10%)
Query: 3 TGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGL 62
+GS+ + GH + +G + G S + S G G+ S G SS
Sbjct: 1512 SGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTS------------GQSSSC 1559
Query: 63 AHCSVSGGDGKMDTMIGDGRSQNC-WGASNSNAGINLNLNPNANPAAW-PVLGHEGTVAT 120
S G G G SQ+ +G S +G + + + P G G+ +
Sbjct: 1560 GQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGS-GS 1618
Query: 121 GNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTS-TSQNVSFSAQPQNL 179
G SS S +G++ G G+ + G + S +S Q+ S S Q
Sbjct: 1619 GRSSSSGQHGSGLGESSG--FGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRG 1676
Query: 180 NTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGG 239
G ++ + + + Q++G G G H GL + SS Q G
Sbjct: 1677 ERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGL--GHSSSHGQHGSG 1734
Query: 240 SAEGIS----------NSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQ 289
S S +SV+G ++ S G+G + +G SS
Sbjct: 1735 SGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFD 1794
Query: 290 KEGSGGNAWDSGPPAGPGIL------AWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEW 343
+EGS S G G G GSG + H GH S +G W
Sbjct: 1795 QEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGW 1854
Query: 344 GKPPNQHSNSDINGKG-----STGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEG 398
+H + G S+ W+S T G H +S+ + S +S G
Sbjct: 1855 SSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHG----SGSGHSSSYEQHGSRSGQSSRG 1910
Query: 399 SSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQT----PV 454
GS + + S G+ G+G + G G Q P R +G GQ+ P
Sbjct: 1911 EQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPS---PSRGRHGSGSGQSSSYGPY 1967
Query: 455 KQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPP 514
+ W P E + + + + +SG GS ++T G +
Sbjct: 1968 GSGSGWSSSRGP-YESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQS 2026
Query: 515 AAV---PANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTW 571
++ A++G S+ + SG S + + GH G+ +++ SP++
Sbjct: 2027 SSCGQHGASSGQSSSHGQHGSGS---SQSSGYGRQGSGSGQSPGHGQRGSGSRQ--SPSY 2081
Query: 572 GEPPKPKSQHWGDGQRSNPAWSAGGGDWADS----SSVLGHLGDGKKNGSGWDADSNRSG 627
G + GQ + G +S SS G G + SG+ +RSG
Sbjct: 2082 GRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSG 2141
Query: 628 SGWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWA--SKPQDNNVSNWGGAASV 685
+SG S++ G+ ++ G Q + + S + + S G ++S
Sbjct: 2142 QSSRGERHGSSSG---SSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSH 2198
Query: 686 KQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDG-TSAWGDPSNYNNKTVNM 744
Q G+G + SS S+ + E G +SA+ + + +
Sbjct: 2199 GQHGSG--------SGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQ 2250
Query: 745 WDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPVSSGWGEMP 804
+ QSST ++T ++S+ H G+ ++S G SG G+ P
Sbjct: 2251 GQHGSTSGQSSTFDQEGSSTGQSSSHGQH----------GSGSSQSSSYGQQGSGSGQSP 2300
Query: 805 NVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPVAASAL 864
S G S S ++++G+ SGSGW G++ +
Sbjct: 2301 --------SRGRHGSGS----GHSSSYGQ-HGSGSGWSSSSGRHGSGSGQSSGFGHHESS 2347
Query: 865 CKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWGNAPKKGLQKG 924
+S Q G GSG + + +S S+SS G+ ++ L G
Sbjct: 2348 SWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHG 2407
Query: 925 MKTSG 929
SG
Sbjct: 2408 QHGSG 2412
Score = 88.6 bits (218), Expect = 5e-17
Identities = 203/963 (21%), Positives = 345/963 (35%), Gaps = 102/963 (10%)
Query: 3 TGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSN-GSAARVWGVATGSSSG 61
+GS + GH + +G + G S + S G G+ S S+ G +G SS
Sbjct: 576 SGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSS 635
Query: 62 LAHCSVSGGDGKMDTMIGDGRSQN-CWGASNSNAGINLNLNPNANPAAWPVL-GHEGTVA 119
G G Q+ G S+ G + + + + + W G G+V+
Sbjct: 636 HGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVS 695
Query: 120 TGNPSSICSPVSAIGQNMG-NQNGNPTGTLGAW---GNLLPQESTEPQTSTSQNVSFSAQ 175
SS S GQ+ G +Q+G+ + + G+ Q S Q +S +S S
Sbjct: 696 --GQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSY- 752
Query: 176 PQNLNTDGPNNTNPMNSSPNPINAMQTNGLPN---WGMAVGMGAIIPPHLQGLPGANGSS 232
G + + SS + + P+ G + G + H G ++
Sbjct: 753 -------GQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCG 805
Query: 233 VSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFS-QG-NGDTVNSALSAKQNGSSS---- 286
+ G A G G G G+++ FS QG +G T + S+ Q+ SSS
Sbjct: 806 HYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSS 865
Query: 287 ------AVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVN 340
+ SG SG PG G GSG + H G RS+S+G +
Sbjct: 866 SYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSG---RSSSSGRH 922
Query: 341 GEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSS 400
G +S K S+G +S T G H +S+ + S +S
Sbjct: 923 GS-----GSGQSSGFGHKSSSG-QSSGYTQHG----SGSGHSSSYEQHGSRSGQSSRSEQ 972
Query: 401 DGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQT----PVKQ 456
GS + + S G+ G+G + G G Q P R +G GQ+ P +
Sbjct: 973 HGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPS---PSRGRHGSGSGQSSSYGPYRS 1029
Query: 457 NTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAA 516
+ W P E + + + + +SG GS ++T G + ++
Sbjct: 1030 GSGWSSSRGP-YESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSS 1088
Query: 517 V---PANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGE 573
A++G S+ + SG S + + GH G+ +++ SP++G
Sbjct: 1089 CGQHGASSGQSSSHGQHGSGS---SQSSGYGRQGSGSGQSPGHGQRGSGSRQ--SPSYGR 1143
Query: 574 PPKPKSQHWGDGQRSNPAWSAGGGDWADS----SSVLGHLGDGKKNGSGWDADSNRSGSG 629
+ GQ + + G +S SS G G + SG+ +RSG
Sbjct: 1144 HGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQS 1203
Query: 630 WNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWA--SKPQDNNVSNWGGAASVKQ 687
+SG S++ G+ ++ G Q + + S + + S G ++S Q
Sbjct: 1204 SRGERHGSSSG---SSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQ 1260
Query: 688 TGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDG-TSAWGDPSNYNNKTVNMWD 746
G+G + SS S+ + E G +SA+ + + +
Sbjct: 1261 HGSG--------SGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQ 1312
Query: 747 RNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPVSSGWGEMPNV 806
+ QSS T + ++T +S+ HR G+ ++S G +G G+ P
Sbjct: 1313 HGSTSGQSS-TFDQEGSSTGQSSSYGHR---------GSGSSQSSGYGRHGAGSGQSP-- 1360
Query: 807 HSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPVAASALCK 866
S G S S ++++G+ SGSGW G++ +
Sbjct: 1361 ------SRGRHGSGS----GHSSSYGQ-HGSGSGWSSSSGRHGSGSGQSSGFGHHESSSW 1409
Query: 867 PASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWGNAPKKGLQKGMK 926
+S Q G GSG + + +S S+SS G+ ++ L G
Sbjct: 1410 QSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQH 1469
Query: 927 TSG 929
SG
Sbjct: 1470 GSG 1472
Score = 85.9 bits (211), Expect = 3e-16
Identities = 155/725 (21%), Positives = 268/725 (36%), Gaps = 97/725 (13%)
Query: 5 SAQGNFTGHTKKTNGNNGTNG-ALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGLA 63
S+ + +G+T+ +G+ ++G S S QS+ G +S GS++ +GS L
Sbjct: 470 SSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLG 529
Query: 64 HCSVSGGDGKMDTMI-----GDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTV 118
H G G+ + R + +G +G + + P +
Sbjct: 530 HSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYES------------- 576
Query: 119 ATGNPSSICSPVSAIGQNMG-NQNGNPTGTLGAWGNLLPQESTEPQTST-SQNVSFSAQP 176
+G+ S + S GQ+ G Q+G+ +G G ST Q+S+ Q+ + S Q
Sbjct: 577 GSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQ---HGSTSGQSSSCGQHGATSGQS 633
Query: 177 QNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQG-----LPGANGS 231
+ G ++ + Q+ G G + H G G +GS
Sbjct: 634 SSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGS 693
Query: 232 SVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQK- 290
Q SG + S G S +G+S+S + +G + ++Q+GSSS +
Sbjct: 694 VSGQSSGFGHKSGSGQSSGYS--QHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSS 751
Query: 291 ---------EGSGGNAWDSGPPAGPGILAWGRGSGN------NGVGNIHSGAWGHPSRST 335
+ SG SG P + G SG+ +G G S + GH +
Sbjct: 752 YGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGH--YES 809
Query: 336 SNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTA 395
+G +G QH + G G S +SQ G+ +S +SSG ++
Sbjct: 810 GSGQASGFG----QHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSS 865
Query: 396 SEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVK 455
S G + + +H G GR G+G G+ GH Q +G GQ+P
Sbjct: 866 SYGQHESASHHASG-RGRHGSGSGQ-------SPGHGQ-----------RGSGSGQSP-- 904
Query: 456 QNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPA 515
+ S RS +G+ + + +S G++ G + + + S +
Sbjct: 905 -SYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSR 963
Query: 516 AVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPP 575
+ G S+ G G S S + + GH G+ + + SP+ G
Sbjct: 964 S-------GQSSRSEQHGSSS-GSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 1015
Query: 576 KPKSQHWGDG-QRSNPAWSAGGGDW---ADSSSVLGHLGDGKKNGSGWDADSNRSGSGWN 631
Q G RS WS+ G + + SS LGH SG+ + SG +
Sbjct: 1016 SGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSG---H 1072
Query: 632 DTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWG--GAASVKQTG 689
+T + +++ G + G++ G + +S+ S +G G+ S + G
Sbjct: 1073 SSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQS-----SGYGRQGSGSGQSPG 1127
Query: 690 TGWIG 694
G G
Sbjct: 1128 HGQRG 1132
Score = 85.9 bits (211), Expect = 3e-16
Identities = 160/714 (22%), Positives = 262/714 (36%), Gaps = 71/714 (9%)
Query: 5 SAQGNFTGHTKKTNGNNGTNG-ALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGLA 63
S+ G + +++ +G+ ++G S S QS+ G +S+GS++R +GS
Sbjct: 2112 SSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSG 2171
Query: 64 HCSVSGGDGKMDTM----IGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVA 119
H G G + G G S + G S +G + + P + + + +
Sbjct: 2172 HGRQGSGSGHSPSRGRHGSGSGHSSS-HGQHGSGSGRSSSRGPYESRSGHSSVFGQHESG 2230
Query: 120 TGNPSSICSPVSAIGQNMGN-QNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQN 178
+G+ S+ S G Q+G+ +G + ST +S Q+ S S+Q +
Sbjct: 2231 SGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQ--EGSSTGQSSSHGQHGSGSSQSSS 2288
Query: 179 LNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANG-----SSV 233
G + + + + ++ G G + H G ++G SS
Sbjct: 2289 YGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSS 2348
Query: 234 SQVSG----GSAEGISNSV--WGLSPGNPATGN---SNSGFSQG---NGDTVNSALSAKQ 281
Q SG GS G S+S G G + G S+SG S +G +L Q
Sbjct: 2349 WQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQ 2408
Query: 282 NGSSSAVQ------KEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRST 335
+GS S + GSG S P G G W G G+ HS GH R +
Sbjct: 2409 HGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGS-GWSSSRGPYESGSGHSSGLGH--RES 2465
Query: 336 SNGVNGEWGKPPNQHSNSDINGK-GSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTT 394
+G + +G+ + +S +G+ GST +S S + H + ++ S
Sbjct: 2466 RSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGY 2525
Query: 395 ASEGSSDG---------SGNHNEGSTGREGTGEGRRRDKGIIDQG--------HIQLPRN 437
+GS G SG+ S GR G+G GR G G H +
Sbjct: 2526 GRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSG 2585
Query: 438 DLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEA-----WGCAATQASNSGGK 492
+G G + +S R ER + + G + Q+S G +
Sbjct: 2586 QSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQ 2645
Query: 493 NDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAP-----SGPGVWGDSISSTAVS 547
GS + + SG ++ +G G S+++ P V+G S + S
Sbjct: 2646 GSGSGQSPSRGRHGSGLGHSSSHG-QHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHS 2704
Query: 548 TAAA---AKSGHAWSGA--ANQEDKSPTWGEPPKPKSQHWGDGQR-SNPAWSAG-GGDWA 600
+A + + SGH S + +S T+ + Q G R S + S+G G A
Sbjct: 2705 SAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGA 2764
Query: 601 DSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTN 654
S L H G +G + SGSG + SG G + G+N
Sbjct: 2765 GSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGGSN 2818
Score = 83.2 bits (204), Expect = 2e-15
Identities = 195/972 (20%), Positives = 357/972 (36%), Gaps = 133/972 (13%)
Query: 5 SAQGNFTGHTKKTNGNNGTNG-ALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGLA 63
S+ G +G+++ +G+ ++G S S QS+ G +S+GS++ +GS L
Sbjct: 236 SSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLG 295
Query: 64 HCSVSGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVATGNP 123
H G + + + G S +G + + + + +++ +G
Sbjct: 296 HGRQGSGSRQSPSHVRHG----------SGSGHSSSHGQHGSGSSYSYSRGHYESGSGQT 345
Query: 124 SSICSPVSAIGQNMG-NQNGNPTG---TLGAWGNLLPQESTEPQ--TSTSQNVSFSAQPQ 177
S S GQ+ G +++G+ +G + G G+ Q S+ Q +S+ Q+ S+
Sbjct: 346 SGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHES 405
Query: 178 NLNTDGPNNTNPMNSSPNPINAMQTNG------LPNWGMAVGMGAIIPPHLQGLPGANG- 230
+ S +P + + +G G G + P++ G ++G
Sbjct: 406 ASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGF 465
Query: 231 ---SSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSS- 286
S S+ S G + S S G + + S + G + S+ S Q+GS S
Sbjct: 466 GHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSR 525
Query: 287 ---AVQKEGSGG--------NAWDSGPPAGPGILAWGRGSGNNG------VGNIHSGAWG 329
+ GSG +SG G GSG + G+ HS G
Sbjct: 526 QSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLG 585
Query: 330 HPSRSTSNGVNGEWGKPPNQHSNSDINGK-GSTGWESPSVTSQNPTVQPGGEHMNSWAKA 388
H + + +G + +G+ + +S +G+ GST +S S G+H
Sbjct: 586 H--QESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSC----------GQH------G 627
Query: 389 ASSGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGI--IDQGHIQLPRNDLDPRVLSN 446
A+SG ++S G GSG+ G++G+G G+ +G D GH + + S
Sbjct: 628 ATSGQSSSHG-QHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGH-----SSSYGQHGSG 681
Query: 447 TGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGG-KNDGSIMNSTNTSS 505
+GW + + + S + + + + +S+S G + GS ++ S
Sbjct: 682 SGWSSSNGPHGSV-SGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSE 740
Query: 506 VSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQE 565
G + + ++ G S + SG G G + + SGH+ S +
Sbjct: 741 QHG----SSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGS 796
Query: 566 DK--SPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADS 623
S + G Q G GQ S G ++ S GH ++GS
Sbjct: 797 GTSCSSSCGHYESGSGQASGFGQHE----SGSGQGYSQHGSASGHFSSQGRHGS---TSG 849
Query: 624 NRSGSGWNDTTRSGNSGWG------NSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVS 677
S SG +D++ +S +G + + + G+ G++ PG Q + Q +
Sbjct: 850 QSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQS--PGHGQRGSGSGQSPSYG 907
Query: 678 NWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNY 737
G+ S + + +G G S +++G+ S G + G S +
Sbjct: 908 R-HGSGSGRSSSSGRHG-------SGSGQSSGFGHKSSSG------QSSGYTQHGSGSGH 953
Query: 738 NNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPVS 797
++ R+ QSS + +++ +++S H G+ +S G
Sbjct: 954 SSSYEQHGSRSG---QSSRSEQHGSSSGSSSSYGQH----------GSGSRQSLGHGQHG 1000
Query: 798 SGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGA 857
SG G+ P S + G S S +++G P SGSGW G +
Sbjct: 1001 SGSGQSP---SPSRGRHGSGSGQS-------SSYG-PYRSGSGWSSSRGPYESGSGHSSG 1049
Query: 858 PVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWGNAP 917
+ +S Q G SG + + + AS +SS G+
Sbjct: 1050 LGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGS 1109
Query: 918 KKGLQKGMKTSG 929
+ G + SG
Sbjct: 1110 SQSSGYGRQGSG 1121
Score = 82.4 bits (202), Expect = 3e-15
Identities = 213/997 (21%), Positives = 357/997 (35%), Gaps = 128/997 (12%)
Query: 4 GSAQGNFTGHTKKTNGNNGTNGALVQSPS-NQSALGAGGANSNGSAARVWGVATGSSSGL 62
GS G GH ++ +G+ QSPS + G+G ++S+G G G SSG
Sbjct: 1119 GSGSGQSPGHGQRGSGSR-------QSPSYGRHGSGSGRSSSSGQH----GSGLGESSGF 1167
Query: 63 AHCSVSGGDGKMDTMIGDGRSQNC-WGASNSNAGINLNLNPNANPAAWPVLGHEGTVATG 121
H S G + G G + +G S +G + + + + H G +G
Sbjct: 1168 GHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSS--SHYGQHGSG 1225
Query: 122 NPSSIC----------SPV-----SAIGQNMGN-QNGNPTGTLGAWGNLLPQESTEPQTS 165
+ S SP S +G + + Q+G+ +G + G P ES +S
Sbjct: 1226 SRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRG---PYESRSGHSS 1282
Query: 166 T-SQNVSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQG 224
Q+ S S + G + + + + + Q++ G + G +
Sbjct: 1283 VFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSY------ 1336
Query: 225 LPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGS 284
G GS SQ SG G + G SP G S SG S G + + + +G
Sbjct: 1337 --GHRGSGSSQSSGYGRHGAGS---GQSPSRGRHG-SGSGHSSSYGQHGSGSGWSSSSGR 1390
Query: 285 SSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWG 344
+ + SG +S G G GSG++ H G SR +G +
Sbjct: 1391 HGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSS 1450
Query: 345 KPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSG 404
QH + G + S + Q+P+ G S ++ S + G S G
Sbjct: 1451 SSYGQHGSGSRQSLGH--GQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRG 1508
Query: 405 NHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEE 464
+ GS+ +G G R + G+ Q ++ G T + ++ +
Sbjct: 1509 PYESGSS--HSSGLGHRESRSGQSSGYGQ--HGSSSGHSSTHGQHGSTSGQSSSCGQHGA 1564
Query: 465 SPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWG 524
S S + + +G G ++Q+S G + GS + + SG P+ +G G
Sbjct: 1565 S--SGQSSSHGQH--GSGSSQSSGYGRQGSGSGQSPGHGQRGSG-SRQSPSYGRHGSGSG 1619
Query: 525 DSNNKAPSGPGVW------------GDSISSTAVSTAAAAKSGHAWSGA-ANQEDKSPTW 571
S++ G G+ G S S + + + SG+ G+ + Q +
Sbjct: 1620 RSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERH 1679
Query: 572 GEPPKPKS---QHWGDGQRSNPAWSAGGGDWADSS-----SVLGHLGDGKKNGSGWDADS 623
G + S QH ++S+ G G S S LGH ++GSG S
Sbjct: 1680 GSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSS 1739
Query: 624 NR----SGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWA--SKPQDNNVS 677
+R S SG + SG G+S + + G+ G G + + S D S
Sbjct: 1740 SRGPYESRSGHSSVFGQHESGSGHS-SAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGS 1798
Query: 678 NWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNY 737
+ G ++S Q G+G Q S G PS R +S++G +
Sbjct: 1799 STGQSSSHGQHGSG-------SSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSG 1851
Query: 738 NNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTH----------------RVETPPPH 781
+ + + + QSS + +++ ++ T H ++
Sbjct: 1852 SGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGE 1911
Query: 782 QAGTQLNRSPLLGPVSSGWGEMPNVHSKTENSWGEPSSPST---LVDNGTAAWGKPPSSG 838
Q G+ S G SG H + + G+ SPS +G ++ P SG
Sbjct: 1912 QHGSSSGSSSSYGQHGSG-SRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSG 1970
Query: 839 SGWGDHPAEPPVAFGRAGAPVAASALCKPASKSMQ-EGWGSGGDEMNLSTSQWEDEEGDV 897
SGW + P G +S L S+S Q G+G G S++ +
Sbjct: 1971 SGWSS--SRGPYESGSG----HSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQ------ 2018
Query: 898 WNNAASQESTSSCSSWGNAPKKGLQKGMKTSGKQDEA 934
+ +AS +S SSC G + + G SG +
Sbjct: 2019 -HGSASGQS-SSCGQHGASSGQSSSHGQHGSGSSQSS 2053
Score = 77.4 bits (189), Expect = 1e-13
Identities = 149/712 (20%), Positives = 259/712 (36%), Gaps = 81/712 (11%)
Query: 4 GSAQGNFTGHTKKTNGNNGTNGALVQSPS-NQSALGAGGANSNGSAARVWGVATGSSSGL 62
GS G GH ++ +G+ QSPS + G+G ++S+G G G SSG
Sbjct: 2059 GSGSGQSPGHGQRGSGSR-------QSPSYGRHGSGSGRSSSSGQH----GPGLGESSGF 2107
Query: 63 AHCSVSGGDGKMDTMIGDGRSQNC-WGASNSNAGINLNLNPNANPAAWPVL--------- 112
H S G + G G + +G S +G + + + +
Sbjct: 2108 GHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSR 2167
Query: 113 -----GHEGTVATGNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTST- 166
G +G+ + +PS + + Q+G+ +G + G P ES +S
Sbjct: 2168 QSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRG---PYESRSGHSSVF 2224
Query: 167 SQNVSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLP 226
Q+ S S + G + + + + + Q++ G + G + H G
Sbjct: 2225 GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSG-- 2282
Query: 227 GANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSS 286
+ SS Q GS + S G +G+S+S G+G +S S+ ++GS S
Sbjct: 2283 SSQSSSYGQQGSGSGQSPSRGRHG-----SGSGHSSSYGQHGSGSGWSS--SSGRHGSGS 2335
Query: 287 AVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKP 346
+ SG +S G G GSG++ H G SR +G +
Sbjct: 2336 G---QSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSS 2392
Query: 347 PNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNH 406
QH + G + S + Q+P+ G S ++ S + G S G +
Sbjct: 2393 YGQHGSGSRQSLGH--GQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPY 2450
Query: 407 NEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESP 466
GS G G R ++G+G Q+ + S
Sbjct: 2451 ESGSGHSSGLGHRESRSG--------------------QSSGYG-----QHGSSSGHSST 2485
Query: 467 RSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDS 526
+ + +G ++ C AS+ + G + ++ SS G + P + G
Sbjct: 2486 HGQHGSTSG-QSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSG 2544
Query: 527 NNKAPS-GPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDG 585
+ ++PS G G SS++ + + + +S ++ + G G
Sbjct: 2545 SRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYG 2604
Query: 586 QR-SNPAWSAGG---GDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGW 641
Q S S+ G G + SSS G G G + SG SGSG + + SG
Sbjct: 2605 QHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQG--SGSGQSPSRGRHGSGL 2662
Query: 642 GNSTNTKANPGTNWGETLKPGPQQN--WASKPQDNNVSNWGGAASVKQTGTG 691
G+S ++ G+ G + GP ++ S + S G +++ Q G+G
Sbjct: 2663 GHS-SSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSG 2713
Score = 73.9 bits (180), Expect = 1e-12
Identities = 154/700 (22%), Positives = 264/700 (37%), Gaps = 100/700 (14%)
Query: 61 GLAHCSVSGGDGKMDT-----------MIGDGRSQNCWGASNSNAGINLNLNPNANPAAW 109
G +C VSG + DT + R ++ + S+ +AG N + + N +
Sbjct: 90 GKDYCQVSGSKLRDDTHQHQEEQEETEKEENKRQESSFSHSSWSAGENDSYSRNVRGSLK 149
Query: 110 PVLGHEGTVA--------TGNPSSICSPVSAIG-QNMGNQNGNPTGTLGAWGNLLPQEST 160
P G E +G +S S+ G QN + + G G+ P
Sbjct: 150 P--GTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSP---- 203
Query: 161 EPQTSTSQNVSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPP 220
+ Q+ S S Q + +T G + S + ++ Q++G G G +
Sbjct: 204 ----NYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQ 259
Query: 221 HL----QGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGN----------SNSGFS 266
H Q G S S S + S S L G +G+ S SG S
Sbjct: 260 HGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHS 319
Query: 267 QGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSG 326
+G + + + G + + SG +SG G G GSG++ H
Sbjct: 320 SSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGS 379
Query: 327 AWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKG-----STGWESP------SVTSQNPTV 375
G S S +G + QH ++ + G S +SP S + Q+P+
Sbjct: 380 TSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPS- 438
Query: 376 QPGGEHMNSWAKAASSGTTAS-EGSSDGSGNH---NEGSTG--REGTGEGRRRDKGIIDQ 429
G+H + +++SSG S G S G G+H +E S+G + G+G G G
Sbjct: 439 --SGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGS 496
Query: 430 GHIQLPRNDLD-PRVLSNTGWGQ--TPVKQNTAWEFE-----ESPRSER-KNDNGTEAWG 480
Q R + S++ +GQ + +Q+ +SP R ++++G+
Sbjct: 497 RSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSR--- 553
Query: 481 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDS 540
Q+S+ G GS +S+ SG + + G +S + SG G G S
Sbjct: 554 ----QSSSYGPHGYGSGRSSSRGPYESG------SGHSSGLGHQESRSGQSSGYGQHGSS 603
Query: 541 ISSTAVSTAAAAKSGHAWS----GAANQEDKSPTW---GEPPKPKSQHWGDGQRSNPAWS 593
++ + SG + S GA + + S G + G G +P+
Sbjct: 604 SGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRG 663
Query: 594 AGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGN-SGWGNSTN-TKANP 651
G D+ SSS H +GSGW + + GS ++ G+ SG G S+ ++
Sbjct: 664 RHGSDFGHSSSYGQH-----GSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGS 718
Query: 652 GTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGTG 691
G++ + ++ S + + S+ G ++S Q G+G
Sbjct: 719 GSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSG 758
Score = 54.3 bits (129), Expect = 1e-06
Identities = 85/372 (22%), Positives = 132/372 (35%), Gaps = 32/372 (8%)
Query: 3 TGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGL 62
+GS + GH + +G + G S + S G G+ S G SS
Sbjct: 2452 SGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTS------------GQSSSC 2499
Query: 63 AHCSVSGGDGKMDTMIGDGRSQNC-WGASNSNAGINLNLNPNANPAAW-PVLGHEGTVAT 120
S G G G SQ+ +G S +G + + + P G G+ +
Sbjct: 2500 GQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGS-GS 2558
Query: 121 GNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTS-TSQNVSFSAQPQNL 179
G SS S +G++ G G+ + G + S +S Q+ S S Q
Sbjct: 2559 GRSSSSGQHGSGLGESSG--FGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRG 2616
Query: 180 NTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGG 239
G ++ + + + + Q++G G G H GL + SS Q G
Sbjct: 2617 ERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGL--GHSSSHGQHGSG 2674
Query: 240 SAEGIS----------NSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQ 289
S S +SV+G ++ S G+G + +G SS
Sbjct: 2675 SGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFD 2734
Query: 290 KEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWG-HPSRSTSNGVNGEWGKPPN 348
+EGS S G G + G G +G G+ S + G H S S + G+ G
Sbjct: 2735 QEGSSTGQSSSYGHRGSG-SSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSG 2793
Query: 349 QHSNSDINGKGS 360
Q S +G GS
Sbjct: 2794 QSSGYSQHGSGS 2805
Score = 38.1 bits (87), Expect = 0.075
Identities = 94/485 (19%), Positives = 173/485 (35%), Gaps = 58/485 (11%)
Query: 454 VKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAP 513
++ +T EE +E++ + E+ + + +S S G+ND N S+ +
Sbjct: 101 LRDDTHQHQEEQEETEKEENKRQES---SFSHSSWSAGENDSYSRNVRG--SLKPGTESI 155
Query: 514 PAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGE 573
+ + +N +G+ S + S+ G SG+ +SP +G+
Sbjct: 156 SRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGR----GQCGSGSG----QSPNYGQ 207
Query: 574 PPKPKSQH-----WGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGS 628
Q G G + +S SS H G G + SG+ +RSG
Sbjct: 208 HGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQH-GSGSGHSSGYGQHGSRSGQ 266
Query: 629 GWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQT 688
+SG S+++ G+ ++L G +Q S+ ++V + G+
Sbjct: 267 SSRGERHRSSSG---SSSSYGQHGSGSRQSLGHG-RQGSGSRQSPSHVRHGSGSGHSSSH 322
Query: 689 GTGWIGGPVPVK----QKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNM 744
G G + S + +G+ + S + G S G S +++ +
Sbjct: 323 GQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQ-----SSGYSKHGSGSGHSS---SQ 374
Query: 745 WDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPVSSGWGEMP 804
+ Q+S++ +++ ++S H E+ H +G G SSG G+ P
Sbjct: 375 GQHGSTSGQASSSGQHGSSSRQSSSYGQH--ESASRHSSGR--------GQHSSGSGQSP 424
Query: 805 NVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPVAASAL 864
+ S PSS G ++ P SGSG+ FG +
Sbjct: 425 GHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSS-------GFGH------HESS 471
Query: 865 CKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWGNAPKKGLQKG 924
+ +S Q G GSG + + +S S+SS G+ ++ L
Sbjct: 472 SEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHS 531
Query: 925 MKTSG 929
SG
Sbjct: 532 RHGSG 536
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 81.3 bits (199), Expect = 8e-15
Identities = 206/945 (21%), Positives = 343/945 (36%), Gaps = 131/945 (13%)
Query: 12 GHTKKTNGNNGTNGALVQSPSNQSAL----GAGGANSNGSAARVWGVA-----TGSSSGL 62
G+ + NG G ++ S+QS+ G+GG+ S + +G + SS+
Sbjct: 354 GYGARENGQPQNCGGQWRTGSSQSSCCGQYGSGGSQSCSNGQHEYGSCGRFSNSSSSNEF 413
Query: 63 AHCSVSGGDGKMDTMI---GDGRSQNCW------------GASNSNAGINLNLNPNANPA 107
+ C G T G G SQ+ G S + +L + + + +
Sbjct: 414 SKCDQYGSGSSQSTSFEQHGTGLSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSS 473
Query: 108 AWPV-LGHEGTVATGNPSSICSPVSAIGQNMG-NQNGNPTGT---LGAWGNLLPQ----- 157
G G+ +G S S GQ+ G Q+G+ +G G G++ Q
Sbjct: 474 GKTSGFGQHGS-GSGQSSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFG 532
Query: 158 --ESTEPQTSTSQNVSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMG 215
ES Q+S Q+ S S+Q G T+ + + + Q+ G +G G
Sbjct: 533 QHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQ--HGLGSGQSTGFGQYGSGSGQS 590
Query: 216 AIIPPHLQGLPGANGSSVSQVSG-GSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVN 274
+ G +GS Q SG G E S G + G +SG SQ +G
Sbjct: 591 SGF--------GQHGSGSGQSSGFGQHESRS--------GQSSYGQHSSGSSQSSG---- 630
Query: 275 SALSAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRS 334
Q+GS ++ SG SG G +G GSG + SG H S S
Sbjct: 631 ----YGQHGS-----RQTSGFGQHGSGSSQSTGFGQYGSGSGQS------SGFGQHVSGS 675
Query: 335 TSNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTT 394
+ G+ S S + G G+ S + G+ SSG +
Sbjct: 676 GQSSGFGQ------HESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQS 729
Query: 395 ASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPV 454
+S G GSG+ G+ G+G G+ G + Q ++G+GQ
Sbjct: 730 SSFG-QHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGS 788
Query: 455 KQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPP 514
+Q + + S S+ G +G + Q++ G GS SG+
Sbjct: 789 RQTSGFGQHGSGSSQ---STGFGQYGSGSGQSAGFGQHGSGS-------GQSSGFGQHES 838
Query: 515 AAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQ---EDKSPTW 571
+ ++ G S + SG G G S T+ + SG +SG +S +
Sbjct: 839 RSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQ-YSGFGQHGSGSGQSSGF 897
Query: 572 GEPPKPKSQHWGDGQ-RSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGW 630
G+ Q+ G GQ S S+ G + SS G+ G +G + +RSGSG
Sbjct: 898 GQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQ 957
Query: 631 NDTTRSGNSGWGNST-----NTKANPGTNWGETLKPGPQQNWASKPQDNNVSN-WG--GA 682
+ SG G S+ + + + +G+ Q N+ ++ S+ +G G+
Sbjct: 958 SSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNYGQHGSGSSQSSGYGQHGS 1017
Query: 683 ASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNY----- 737
+S + TG G + S + +G+ + S + GT + G S +
Sbjct: 1018 SSGQTTGFG-------QHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGS-GQSSGFGQYES 1069
Query: 738 NNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRV---ETPPPHQAGTQLNRSPLLG 794
++ + + QSS + + T+ HR ++ Q G+ +S G
Sbjct: 1070 RSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGFG 1129
Query: 795 PVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGR 854
SG G+ S S+ +GT G SSG G + + P +FG+
Sbjct: 1130 QHGSGTGKSSGFAQHEYR-----SGQSSYGQHGT---GSSQSSGCGQHESGSGPTTSFGQ 1181
Query: 855 --AGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDV 897
+G+ +S+ + G+G G ST + E V
Sbjct: 1182 HVSGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGESQQV 1226
Score = 69.7 bits (169), Expect = 2e-11
Identities = 167/779 (21%), Positives = 275/779 (35%), Gaps = 138/779 (17%)
Query: 4 GSAQGNFTGHTKKTNGNNGTNG-ALVQSPSNQSALGAGGANSNGSAAR-VWGVATGSSSG 61
GS G +G + G+ +G +S S+QS+ G G+ S+ S+ G ++G + G
Sbjct: 888 GSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTFG 947
Query: 62 LAHCSVSGGDGKMDTMIGDGRSQNC-WGASNSNAGINLNLNPNANPAAWPVLGHEG---- 116
G G G Q+ +G S +G + + + ++ G G
Sbjct: 948 FGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNYGQHGSGSS 1007
Query: 117 --------------TVATGNPSSICSPVSAIGQNMGN--------QNGNPTGTLGAWGNL 154
T G S S GQ+ Q+G +G +G
Sbjct: 1008 QSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQY 1067
Query: 155 LPQESTEPQTSTSQNVSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGM 214
ES Q+S Q+ S S+Q G N+ + + Q++G +G G
Sbjct: 1068 ---ESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQ 1124
Query: 215 GAIIPPHLQGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSG----FSQGNG 270
+ H G ++G + + G + S G TG+S S G+G
Sbjct: 1125 SSGFGQHGSGTGKSSGFAQHEYRSGQS----------SYGQHGTGSSQSSGCGQHESGSG 1174
Query: 271 DTVNSA--LSAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNN-GVGN----- 322
T + +S N SSS G + DSG G G +G GSG + G+G
Sbjct: 1175 PTTSFGQHVSGSDNFSSS-------GQHISDSGQSTGFG--QYGSGSGQSTGLGQGESQQ 1225
Query: 323 IHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHM 382
+ SG+ H + T++G +HS S G+G + VT + + Q
Sbjct: 1226 VESGSTVHGRQETTHGQTIN----TTRHSQS---GQGQSTQTGSRVTRRRRSSQSENSDS 1278
Query: 383 NSWAKAASSGTTASEGSSDGSGNH--NEGST--GREGTGEGRRRDKGIIDQGHIQLPRND 438
+K + SE +G+H GST R+GT G+R D GH
Sbjct: 1279 EVHSKVSHRH---SEHIHTQAGSHYPKSGSTVRRRQGTTHGQRGDT--TRHGH------- 1326
Query: 439 LDPRVLSNTGWGQ---TPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDG 495
+G GQ T + + F S ++ + +G + Q + G G
Sbjct: 1327 --------SGHGQSTQTGSRTSGRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHG 1378
Query: 496 SIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSG 555
++ + + + A ++G G S + + +G
Sbjct: 1379 ESESTVHERHETTYGQTGEATGHGHSGHGQSTQRG--------------------SRTTG 1418
Query: 556 HAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGD---- 611
SG + D G +P+SQ GQ + +G + G GD
Sbjct: 1419 RRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESGSTVHGRHGTTHGQTGDTTRH 1478
Query: 612 -----GKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNST---NTKANPGTNWGETLKPGP 663
GK G + + R GSG ++++ S G+ T +T G+ GE+
Sbjct: 1479 AHYHHGKSTQRG-SSTTGRRGSGHSESSDSEVHSGGSHTHSGHTHGQSGSQHGESESIIH 1537
Query: 664 QQNWASKPQ--DNNVSNWGGAASVKQTGTGWIGGPVPVKQKDS-SEATGWEEPSPPSIR 719
++ + Q D ++ G QTG+ G +Q+ S SE+T E S S R
Sbjct: 1538 DRHRITHGQTGDTTRHSYSGHEQTTQTGSRTTG-----RQRTSHSESTDSEVHSGGSHR 1591
Score = 54.3 bits (129), Expect = 1e-06
Identities = 103/479 (21%), Positives = 165/479 (34%), Gaps = 63/479 (13%)
Query: 227 GANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNG--- 283
G SG S G S G+ TG SG S+ + V+S S +G
Sbjct: 1845 GTTHGQTGDTSGHSQSGHGQST---QSGSSTTGRRRSGHSESSDSEVHSGGSHTHSGHTH 1901
Query: 284 ---------SSSAVQKE-----GSGGNAWDSGPPA-GPGILAWGRGSGNNGVGNIHSGAW 328
S S V K G G+ + G P+ G I R +G G G+
Sbjct: 1902 SQARSQHGESESTVHKRHQTTHGQTGDTTEHGHPSHGQTIQTGSRTTGRRGSGHSEYSDS 1961
Query: 329 GHPS---RSTSNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVT----SQNPTVQPGGEH 381
PS + S +G+ G + +S G+T ++ T S + G
Sbjct: 1962 EGPSGVSHTHSGHTHGQAGSHYPESGSSVHERHGTTHGQTADTTRHGHSGHGQSTQRGSR 2021
Query: 382 MNSWAKAASSGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDP 441
+ S + SEG S S H+ + G+ G+ G + + H D
Sbjct: 2022 TTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQHGESGSS--VHERHGTTHGQTGDT 2079
Query: 442 RVLSNTGWGQTPVKQNTAWEFEESPRSERKND---------NGTEAWGCAATQASNSGGK 492
+++G GQ+ + + S SE + + +G A +Q SG
Sbjct: 2080 TRHAHSGHGQSTQRGSRTAGRRGSGHSESSDSEVHSGVSHTHSGHTYGQARSQHGESGSA 2139
Query: 493 ---NDGSIMNSTNTSSVSGWVNAPPAAVPAN--TGWGDSNNKAPSGPGVWGDSISSTAVS 547
G+I T ++ G + + TG S++ S V ++ + +
Sbjct: 2140 IHGRQGTIHGQTGDTTRHGQSGHGQSTQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGH 2199
Query: 548 TAAAAKSGHAWSGAANQEDKSPTWGEP-PKPKSQHWGDGQRSNPAWSAGG---------- 596
T + A S H SG++ + T G+ + H+G GQ + G
Sbjct: 2200 THSQAGSRHGQSGSSGHGRQGTTHGQTGDTTRHAHYGYGQSTQRGSRTTGRRGSGHSESS 2259
Query: 597 -------GDWADSSSVLGHLGDGKKN-GSGWDADSNRSGSGWNDTTRSGNSGWGNSTNT 647
G S + G G ++ GS + DTTR G+SG+G ST T
Sbjct: 2260 DSEVHSWGSHTHSGHIQGQAGSQQRQPGSTVHGRLETTHGQTGDTTRHGHSGYGQSTQT 2318
Score = 52.0 bits (123), Expect = 5e-06
Identities = 142/690 (20%), Positives = 237/690 (34%), Gaps = 83/690 (12%)
Query: 9 NFTGHTKKTNGNNGTNGA--LVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGLAHCS 66
+++GH + T + T G S S S + +GG++ S +G A GS +
Sbjct: 1554 SYSGHEQTTQTGSRTTGRQRTSHSESTDSEVHSGGSHRPHSREHTYGQA-GSQHEEPEFT 1612
Query: 67 VSGGDGKMDTMIGD--GRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVATGNPS 124
V G IGD G S + G S +++ + H G T
Sbjct: 1613 VHERHGTTHGQIGDTTGHSHSGHGQSTQRGSRTTGRQRSSHSESSDSEVHSGVSHT---- 1668
Query: 125 SICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLNTDGP 184
+ G+ +G G +++P+ T + L T
Sbjct: 1669 -----------HTGHTHGQAGSQHGQSESIVPERHGTTHGQTGDTTRHAHYHHGLTTQTG 1717
Query: 185 NNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGSAEGI 244
+ T S G + + G + H +G + SQ G +E I
Sbjct: 1718 SRTTGRRGS----------GHSEYSDSEGYSGVSHTHSGH---THGQARSQ--HGESESI 1762
Query: 245 SNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPPA 304
+ G G TG++ G+G + + SS + S G++ S P
Sbjct: 1763 VHERHGTIHGQ--TGDTTRHAHSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPH 1820
Query: 305 GPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEW-GKPPNQHSNSDINGKGSTGW 363
G GS + +I G T++G G+ G + H S +G +TG
Sbjct: 1821 SRGHTHGQAGSQHGESESIVDERHG-----TTHGQTGDTSGHSQSGHGQSTQSGSSTTGR 1875
Query: 364 E-SPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNE-----GSTGREG-- 415
S S + V GG H +S + + + E S H G T G
Sbjct: 1876 RRSGHSESSDSEVHSGGSHTHSGHTHSQARSQHGESESTVHKRHQTTHGQTGDTTEHGHP 1935
Query: 416 ----TGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERK 471
T + R G GH + ++ P +S+T G T + + + ES S +
Sbjct: 1936 SHGQTIQTGSRTTGRRGSGHSEYSDSE-GPSGVSHTHSGHTHGQAGS--HYPESGSSVHE 1992
Query: 472 NDNGTEAWGCAATQASNSG---GKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNN 528
T T+ +SG GS S S + ++ + ++T G ++
Sbjct: 1993 RHGTTHGQTADTTRHGHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHG 2052
Query: 529 KAPSGPGVWGDSI----SSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQ---- 580
+A S G G S+ +T T + H+ G + Q S T G S+
Sbjct: 2053 QAGSQHGESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRG-SRTAGRRGSGHSESSDS 2111
Query: 581 ---------HWGD--GQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSG 629
H G GQ + +G ++ G GD ++G S ++GS
Sbjct: 2112 EVHSGVSHTHSGHTYGQARSQHGESGSAIHGRQGTIHGQTGDTTRHGQSGHGQSTQTGSR 2171
Query: 630 WNDTTRSGNSGWGNS-TNTKANPGTNWGET 658
RS +S +S +++A+P T+ G T
Sbjct: 2172 TTGRQRSSHSESSDSEVHSEASP-THSGHT 2200
Score = 44.7 bits (104), Expect = 8e-04
Identities = 122/648 (18%), Positives = 215/648 (33%), Gaps = 64/648 (9%)
Query: 280 KQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGV 339
+ N + S ++++ G + SG G ++ G +S G P ++S+
Sbjct: 250 ESNSTQSRIREQKLGSSCSGSGDS----------GRRSHACGYSNSSGCGRPQNASSSCQ 299
Query: 340 NGEWGKPPNQHS------NSDINGKGSTGWES---PSVTSQNPTVQPGGEHMNSWAKAAS 390
+ +G NQ S S I G G S PS Q + + A
Sbjct: 300 SHRFGGQGNQFSYIQSGCQSGIKGGQGHGCVSGGQPSGCGQPESNPCSQSYSQRGYGARE 359
Query: 391 SGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWG 450
+G + G +G+ G+ G+G + G + G N S
Sbjct: 360 NGQPQNCGGQWRTGSSQSSCCGQYGSGGSQSCSNGQHEYGSCGRFSNSSSSNEFSKCDQY 419
Query: 451 QTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWV 510
+ Q+T++E + S+ +G E C + Q + S SG
Sbjct: 420 GSGSSQSTSFEQHGTGLSQ---SSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSSGKT 476
Query: 511 NAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPT 570
+ +G G S+ G G G S + + SG G+ + +
Sbjct: 477 SG---FGQHGSGSGQSSGFGQCGSGS-GQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFG 532
Query: 571 WGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGH-LGDGKKNGSGWDADSNRSGSG 629
E +S + G S+ + G ++S H LG G+ G G + SG
Sbjct: 533 QHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSG 592
Query: 630 WNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWG--GAASVKQ 687
+ G + + +++G+ Q + + S +G G+ S +
Sbjct: 593 FGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQS 652
Query: 688 TGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDR 747
TG G G +G + S + E G S++G ++++
Sbjct: 653 TGFGQYGSGSGQSSGFGQHVSGSGQSSGFG---QHESRSGHSSYGQHGFGSSQSSGYGQH 709
Query: 748 NNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPVSSGWGEMPNVH 807
+ Q+S ++ ++S H G+ +S G SG G+
Sbjct: 710 GSSSGQTSGFGQHELSSGQSSSFGQH----------GSGSGQSSGFGQHGSGSGQ----- 754
Query: 808 SKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPVAASALCKP 867
+ +G+ S S G + G S SG+G H + FG+ G
Sbjct: 755 ---SSGFGQHESRSGQSSYGQHSSGS--SQSSGYGQHGSRQTSGFGQHG----------- 798
Query: 868 ASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQ-ESTSSCSSWG 914
+ S G+G G S + G ++ Q ES S SS+G
Sbjct: 799 SGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYG 846
Score = 39.3 bits (90), Expect = 0.034
Identities = 142/705 (20%), Positives = 239/705 (33%), Gaps = 86/705 (12%)
Query: 252 SPGNPATGNSNSGFSQGNGDTVNSALSAK----QNGSSSAVQKEGSGGNAWDSGPPAGPG 307
+PG+ + G +S +S+G +S S ++GS+S ++ G GN SG G
Sbjct: 122 TPGHKS-GYRHSSWSEGEEHGYSSGHSRGTVKCRHGSNS--RRLGRQGNLSSSGNQEGSQ 178
Query: 308 ILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGSTGWESPS 367
G++ G G S +N P + +G GS WE
Sbjct: 179 KRYHRSSCGHSWSGG--KDRHGSSSVELRERINKSHISPSRESGEEYESGSGSNSWERKG 236
Query: 368 VTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDG-SGNHNEGSTGREGTGEGRRRDKGI 426
+ ++ G NS S S G SG + +G GR ++
Sbjct: 237 HGGLSCGLETSGHESNSTQSRIREQKLGSSCSGSGDSGRRSHACGYSNSSGCGRPQNASS 296
Query: 427 IDQGH--------IQLPRNDLDPRVLSNTGWGQTPVKQ-NTAWEFEESPRSERKNDNGTE 477
Q H ++ + G G Q + + E +P S+ + G
Sbjct: 297 SCQSHRFGGQGNQFSYIQSGCQSGIKGGQGHGCVSGGQPSGCGQPESNPCSQSYSQRG-- 354
Query: 478 AWGCAAT-QASNSGGK-NDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPG 535
+G Q N GG+ GS +S SG + G +N + S
Sbjct: 355 -YGARENGQPQNCGGQWRTGSSQSSCCGQYGSGGSQSCSNGQHEYGSCGRFSNSSSSNEF 413
Query: 536 VWGDSISSTAVSTAAAAKSGHAWSGAANQED----KSPTWGEPPKPKSQHWGDGQRSNPA 591
D S + + + + G S ++ E T G+ SQ G Q + +
Sbjct: 414 SKCDQYGSGSSQSTSFEQHGTGLSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSS 473
Query: 592 WSAGG----GDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNT 647
G G + SS G G G SG+ + SG SG G+ +
Sbjct: 474 GKTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQS------SGFGQHGSVSGQ 527
Query: 648 KANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVKQKDSSEA 707
+ G + + + Q+ + Q S +G S + +G G G S ++
Sbjct: 528 SSGFGQHESRSRQSSYGQHGSGSSQS---SGYGQYGSRETSGFGQHG-------LGSGQS 577
Query: 708 TGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTT 767
TG+ + S +S +G + + ++ + QSS +++ ++ ++
Sbjct: 578 TGFGQYGSGS--------GQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSS 629
Query: 768 TSNTTHRVETPPPHQAGTQLNRSPLLGPVSSGWGEMPNVHSKTENS-----WGEPSSPST 822
+T Q G+ ++S G SG G+ S +G+ S S
Sbjct: 630 GYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSG 689
Query: 823 LVDNGTAAWGKPPSSG-----------SGWGDH--PAEPPVAFGRAGAPVAASALCKPAS 869
G +G SSG SG+G H + +FG+ G+ S S
Sbjct: 690 HSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQS------S 743
Query: 870 KSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWG 914
Q G GSG +S + E ++ Q S+ S S G
Sbjct: 744 GFGQHGSGSG------QSSGFGQHESRSGQSSYGQHSSGSSQSSG 782
Score = 35.8 bits (81), Expect = 0.37
Identities = 114/508 (22%), Positives = 177/508 (34%), Gaps = 82/508 (16%)
Query: 227 GANGSSVSQV-SGGS--------AEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSAL 277
G + SS S+V SGGS G + S G S G+ G + Q GDT A
Sbjct: 1423 GHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGES-GSTVHGRHGTTHGQ-TGDTTRHAH 1480
Query: 278 ----SAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSR 333
+ Q GSS+ ++ + DS +G G G +G + S + H
Sbjct: 1481 YHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSHTHSGHTHGQSGSQHGESESIIHDRH 1540
Query: 334 STSNGVNGEWGKPP-NQHSNSDINGKGSTGWESPSVT-SQNPTVQPGGEHM-----NSWA 386
++G G+ + + H + G +TG + S + S + V GG H +++
Sbjct: 1541 RITHGQTGDTTRHSYSGHEQTTQTGSRTTGRQRTSHSESTDSEVHSGGSHRPHSREHTYG 1600
Query: 387 KAASS------------GTTASE-GSSDGSGNHNEG-STGREGTGEGRRRDKGIIDQGHI 432
+A S GTT + G + G + G ST R GR+R H
Sbjct: 1601 QAGSQHEEPEFTVHERHGTTHGQIGDTTGHSHSGHGQSTQRGSRTTGRQRSS------HS 1654
Query: 433 QLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGG- 491
+ +++ V S+T G T + + ES ER + G A G
Sbjct: 1655 ESSDSEVHSGV-SHTHTGHTHGQAGSQHGQSESIVPERHGTTHGQT-GDTTRHAHYHHGL 1712
Query: 492 -KNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGD-------SISS 543
GS S S + ++ + ++T G ++ +A S G +I
Sbjct: 1713 TTQTGSRTTGRRGSGHSEYSDSEGYSGVSHTHSGHTHGQARSQHGESESIVHERHGTIHG 1772
Query: 544 TAVSTAAAAKSGHAWS-------------GAANQEDKSPTWGEPPKPKSQHWGDGQRSNP 590
T A SGH S G + D G +P S+ GQ
Sbjct: 1773 QTGDTTRHAHSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHTHGQ---- 1828
Query: 591 AWSAGGGDWADSSSVL--------GHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWG 642
G +S S++ G GD + S +SGS RSG+S
Sbjct: 1829 ----AGSQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRSGHSESS 1884
Query: 643 NSTNTKANPGTNWGETLKPGPQQNWASK 670
+S T+ G T Q+ S+
Sbjct: 1885 DSEVHSGGSHTHSGHTHSQARSQHGESE 1912
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 77.0 bits (188), Expect = 1e-13
Identities = 140/802 (17%), Positives = 315/802 (39%), Gaps = 44/802 (5%)
Query: 5 SAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANS-----NGSAARVWGVATGSS 59
S QG+ + ++NGN+ N +S +N S+ G NS NG+ + G S
Sbjct: 459 SMQGDDPNSSDESNGNDDANS---ESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDS 515
Query: 60 SGLAHCSVS-----------------GGDGKMDTMIGDGR-SQNCWGASNSNAGINLNLN 101
+ + S G GK D+ D S N +S+S+ + + N
Sbjct: 516 DSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSN 575
Query: 102 PNANPAAWPVLGHEGTVATGNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTE 161
+++ + + + + + SS S S + + + + + + + +S++
Sbjct: 576 SSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSD 635
Query: 162 P--QTSTSQNVSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIP 219
++ +S + S + + ++D N++N +SS + ++ ++ + + +
Sbjct: 636 SDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDS 695
Query: 220 PHLQGLPGANGSSVSQVSGGSAEGISNSVWG-LSPGNPATGNSNSGFSQGNGDTVNSALS 278
+ ++ SS S S S SNS S + ++ +SNS S + D+ NS+ S
Sbjct: 696 SNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDS 755
Query: 279 AKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNG 338
+ + SS++ S ++ S S ++ N + S +S+
Sbjct: 756 SDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDS 815
Query: 339 VNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEG 398
+ + + ++SD + ++ S S S + + +S + SS ++ S
Sbjct: 816 SDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSN 875
Query: 399 SSDGS--GNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQ 456
SSD S + NE S + + D D N D SN+
Sbjct: 876 SSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSS------NSSDSSDSSNSSDSSESSNS 929
Query: 457 NTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAA 516
+ +S S +D+ + ++ +S+S +D S NS+++S S ++ ++
Sbjct: 930 SDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSS 989
Query: 517 VPANTG-WGDSNNKAPSGPGV-WGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEP 574
+++ DS+N + S DS +S+ S ++ + + S +++ D S +
Sbjct: 990 DSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSS 1049
Query: 575 PKPKSQHWGD----GQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGW 630
S + D S+ + S+ D +DSS + S +DS+ S
Sbjct: 1050 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSS 1109
Query: 631 NDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGT 690
+ + S +S NS+++ + ++ + +S+ D++ S+ +S +
Sbjct: 1110 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSS 1169
Query: 691 GWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNP 750
DSS+++ + S S D S+ S+ ++ + + D ++
Sbjct: 1170 DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS-DSSDSSDSSDSSDSSDSSDSSDSSDS 1228
Query: 751 VIQSSTTTNTTTTTTTTTSNTT 772
+ ++ ++ ++ ++ +SN++
Sbjct: 1229 SDSNESSDSSDSSDSSDSSNSS 1250
Score = 69.3 bits (168), Expect = 3e-11
Identities = 109/679 (16%), Positives = 263/679 (38%), Gaps = 30/679 (4%)
Query: 3 TGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGL 62
+ S+ + + ++ ++ ++ + S S+ S+ + +NS+ S+ + SS
Sbjct: 645 SNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDS 704
Query: 63 AHCSVSGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVATGN 122
+ S S D+ + + +S+S+ N + + +++ ++ + + ++ +
Sbjct: 705 SDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNS 764
Query: 123 PSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLNTD 182
S S S+ + N + + + + + S +S S + S S+ + N+
Sbjct: 765 SDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSS 824
Query: 183 GPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGSAE 242
+N++ + S N ++ ++ + + ++ SS S S S++
Sbjct: 825 DSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNR------SDSSNSSDSSDSSDSSNSSD 878
Query: 243 GISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDSGP 302
+S S + + +S++ + D+ NS+ S+ + SS + + S N+ S
Sbjct: 879 SSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSD- 937
Query: 303 PAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGSTG 362
S ++ + + S ++S+ N N +SD + +
Sbjct: 938 -----------SSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSS 986
Query: 363 WESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGSTGREGTGEGRRR 422
S S S + + + + ++ S ++ +S S N ++ S + +
Sbjct: 987 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSS 1046
Query: 423 DKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWGCA 482
D D + D S++ + + E +S S +D+ +
Sbjct: 1047 DSS--DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSD 1104
Query: 483 ATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDSIS 542
++ +S+S +D S +S+N+S S ++ ++ +N+ DS++ + S DS
Sbjct: 1105 SSDSSDSSDSSDSS--DSSNSSDSSDSSDSSDSSDSSNSS--DSSDSSESSDS--SDSSD 1158
Query: 543 STAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAW----SAGGGD 598
S+ S ++ + S ++N D S + S D S+ + S+ D
Sbjct: 1159 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1218
Query: 599 WADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGET 658
+DSS + + S +DS+ S + + + S +S + +N +++ + G
Sbjct: 1219 SSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNG 1278
Query: 659 LKPGPQQNWASKPQDNNVS 677
G + S+ D+N S
Sbjct: 1279 NNNGSDSDSDSEGSDSNHS 1297
Score = 67.0 bits (162), Expect = 2e-10
Identities = 179/915 (19%), Positives = 313/915 (34%), Gaps = 143/915 (15%)
Query: 82 RSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVATGNPSSICSPVSAIGQNMGNQN 141
+S N + SN + LN + VL HEG + G
Sbjct: 30 KSMNLHLLARSNVSVQDELNASGTIKESGVLVHEGDRGRQENTQDGHKGEGNGSKWAEVG 89
Query: 142 GNPTGTLGAW----GNLLPQESTEPQTSTSQNVSFSAQPQNLNTDGPNNTNPMNSSPNPI 197
G T GN+ + T + + +N+ +G + +
Sbjct: 90 GKSFSTYSTLANEEGNIEGWNGDTGKAETYGHDGIHGKEENITANGIQGQVSIIDNAGAT 149
Query: 198 NAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGS-SVSQVSGGSAEGISNSVWGLSPGNP 256
N TNG N G + G G N +V Q G G +NS N
Sbjct: 150 NRSNTNG--NTDKNTQNGDV------GDAGHNEDVAVVQEDGPQVAGSNNST-----DNE 196
Query: 257 ATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAW---DSGPPAGPGI----- 308
NS ++GN + +++K+NG+ A G+G +A G P+G G
Sbjct: 197 DEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDED 256
Query: 309 ----------LAWGRGSGNNG---VGNIHSGAWGHPSRSTSNGVNGEWGKPPNQ---HSN 352
G+ S NN G H H S N + E+ P + H+
Sbjct: 257 EGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNE 316
Query: 353 SDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAK-------------AASSGTTASEGS 399
D + + S + N G + + K S T A S
Sbjct: 317 VDGDKTSKSEENSAGIPEDN-----GSQRIEDTQKLNHRESKRVENRITKESETHAVGKS 371
Query: 400 SD------GSGNHNEGSTGREGTGEGRRRDKG----IIDQGHIQL---------PRNDLD 440
D G + N T G G + DKG I+ +G+++ P +
Sbjct: 372 QDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSE 431
Query: 441 PRVL---SNTG------------------WGQTPVKQNTAWEFEESPRSERKNDNGTEAW 479
P SNTG G P N++ E + + ++DN + +
Sbjct: 432 PGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDP---NSSDESNGNDDANSESDNNSSSR 488
Query: 480 GCAATQASNSGGKNDGSIMNST--NTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVW 537
G A+ + S +GS + S + N + N G D N+K+ SG G
Sbjct: 489 GDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNG-NDDNDKSDSGKGKS 547
Query: 538 GDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGG 597
S S ++ S+ ++ S + S +++ S + + S D S+ + S+
Sbjct: 548 DSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDS--DSSDSDSSDSSDSDSSDSSNSSDSS 605
Query: 598 DWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGE 657
D +DSS + S +DS++S S +D+ +S NS+++ N ++
Sbjct: 606 DSSDSSD-----SSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSS 660
Query: 658 TLKPGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPS 717
+ +S D++ S+ +S DSS+++ E S S
Sbjct: 661 NSSNSSDSSDSSDSSDSSSSSDSSNSS---------------DSSDSSDSSNSSESSDSS 705
Query: 718 IRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVET 777
D S D S+ +N + D +N S ++ ++ ++ ++ +SN++ ++
Sbjct: 706 -------DSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDS 758
Query: 778 PPPHQAGTQLNRSPLLGPVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSS 837
+ + S SS + N ++S SS S+ N + + SS
Sbjct: 759 SDSSNSSDSSDSSD-----SSDSSDSSNSSDSNDSSNSSDSSDSS---NSSDSSNSSDSS 810
Query: 838 GSGWGDHPAEPPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDV 897
S + + + S+ +S S GS D N S S + D
Sbjct: 811 DSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDS 870
Query: 898 WNNAASQESTSSCSS 912
+++ S +S+ S S
Sbjct: 871 SDSSNSSDSSDSSDS 885
Score = 61.2 bits (147), Expect = 8e-09
Identities = 122/701 (17%), Positives = 260/701 (37%), Gaps = 73/701 (10%)
Query: 2 ATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSG 61
++ S+ + + + ++ N+ ++ S S+ S+ +SN S + + S S
Sbjct: 557 SSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDS-----SDSSDSS 611
Query: 62 LAHCSVSGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVATG 121
+ S D K D+ + S + S+S+ + + + N++ + +
Sbjct: 612 DSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSS------DSSNSSNS 665
Query: 122 NPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLNT 181
+ SS S S + + N + + N ES++ S+ + S S+ N N+
Sbjct: 666 SDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSN--SSESSDSSDSSDSDSSDSSDSSNSNS 723
Query: 182 DGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGSA 241
+++N +SS + ++ ++ + + + + ++ SS S S S+
Sbjct: 724 SDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS 783
Query: 242 EGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGS-GGNAWDS 300
+ SN S + ++ +S+S S + D+ +S+ S N S S+ + S N+ DS
Sbjct: 784 D--SNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS 841
Query: 301 GPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGS 360
+ G S ++ + + + S +SN + N+ SNS + S
Sbjct: 842 SDSSDSSD---GSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSS 898
Query: 361 TGWESPSVTSQNPT-------VQPGGEHMNSWAKAASSGTTASEGSSDGS--GNHNEGST 411
+S S S N + E NS + SS ++ S SSD S N ++ S
Sbjct: 899 NSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSN 958
Query: 412 GREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERK 471
+ + D D + D S++ + + + +S S
Sbjct: 959 SSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNS 1018
Query: 472 NDNGTEAWGCAATQASNSGGKNDGS----------IMNSTNTSSVSGWVNAPPAAVPANT 521
+D+ + ++ +S+S +D S NS+++S S ++ ++ +++
Sbjct: 1019 SDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1078
Query: 522 G-------WGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEP 574
DS+N + S DS S+ S ++ + S +++ D S +
Sbjct: 1079 SDSSESSDSSDSSNSSDSSDS--SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1136
Query: 575 PKPKSQHWGDGQRSNPAW-------------------------SAGGGDWADSSSVLGHL 609
S D S+ + S+ D +DSS
Sbjct: 1137 DSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD-SSDS 1195
Query: 610 GDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKAN 650
D + D+ + S +D++ S +S + +N ++
Sbjct: 1196 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSD 1236
>gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1230
Score = 72.0 bits (175), Expect = 5e-12
Identities = 98/445 (22%), Positives = 167/445 (37%), Gaps = 62/445 (13%)
Query: 445 SNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTS 504
S +GW + S S N A+ S+SG + + + +T
Sbjct: 16 SGSGWASSSA----------SGASTPSNSGWASPSASGASIPSDSGWASPSA--SGASTP 63
Query: 505 SVSGWVN--APPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAA 562
S SGW + A A++P+++GW + S P G + S +A + + SG A +
Sbjct: 64 SNSGWASFSASWASIPSDSGWASPSASWASTPSDSGWA-SPSASGASIPSDSGWASPSVS 122
Query: 563 NQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDAD 622
S W P G S+ W++ WA +SS G S +
Sbjct: 123 GASIPSAFWASPSAS-----GASTPSDSGWASPSASWASTSSDSGWASPSASWTSPSASC 177
Query: 623 SNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGA 682
++ S SG + +SGW + + +P T+W + WAS P D+ ++ A
Sbjct: 178 ASSSASG---ASTPSDSGWASPSVFWVSPSTSWASS---PSDFGWASTPSDSGWAS-SSA 230
Query: 683 ASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPP--SIRRKMEIDDGTSAWGDPS-NYNN 739
+ + + +G +S +GW PS S S W S ++++
Sbjct: 231 SCISPSASG----------ASTSSDSGWASPSASWVSTSTSRASTSSDSGWASSSASWDS 280
Query: 740 KTVNM-WDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPVSS 798
T + W + SS+ + + + + +S+ + + + S P S
Sbjct: 281 ITSDSGWVCPSASWASSSASWASAPSDSGSSSPSVSRASTLSVSGWASFSASGASAPSDS 340
Query: 799 GW--GEMPNVHSKTENSWGEPSS--PSTLVDNG----TAAWGKPPSSG------SGWGDH 844
GW V + +++ W PS+ ST D+G +A+W P +SG SGW
Sbjct: 341 GWTSHSASGVSTTSDSGWASPSASGASTSSDSGWASPSASWASPSASGASTPSDSGWAS- 399
Query: 845 PAEPPVAFGRA--GAPVAASALCKP 867
P A G + AP C P
Sbjct: 400 ----PSASGASMPSAPSLCPGSCFP 420
Score = 67.0 bits (162), Expect = 2e-10
Identities = 91/442 (20%), Positives = 158/442 (35%), Gaps = 63/442 (14%)
Query: 214 MGAIIPPHLQGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGF---SQGNG 270
M + + G+ +GS + S A SNS W + A+ S+SG+ S
Sbjct: 1 MASFLFSRASGVSTPSGSGWASSSASGASTPSNSGWASPSASGASIPSDSGWASPSASGA 60
Query: 271 DTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGH 330
T +++ A + S +++ + SG + + + P W S +G W
Sbjct: 61 STPSNSGWASFSASWASIPSD-SGWASPSASWASTPSDSGWASPSA-SGASIPSDSGWAS 118
Query: 331 PSRSTSNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAAS 390
PS S ++ + W P S S + +GW SPS + + + G WA ++
Sbjct: 119 PSVSGASIPSAFWASP----SASGASTPSDSGWASPSASWASTSSDSG------WASPSA 168
Query: 391 SGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWG 450
S T+ S + S +G D G + + S+ GW
Sbjct: 169 SWTSPSASCASSS-----------ASGASTPSDSGWASPSVFWVSPSTSWASSPSDFGWA 217
Query: 451 QTPVKQNTAWEFEE----SPRSERKNDNGTEAWGC-----AATQASNSGGKNDGSIMNST 501
TP ++ W SP + + + W +T S + +D +S+
Sbjct: 218 STP--SDSGWASSSASCISPSASGASTSSDSGWASPSASWVSTSTSRASTSSDSGWASSS 275
Query: 502 ----NTSSVSGWVNAPPAAVPANTGW----GDSNNKAPS-------GPGVWGDSISSTAV 546
+ +S SGWV + ++ W DS + +PS W +S A
Sbjct: 276 ASWDSITSDSGWVCPSASWASSSASWASAPSDSGSSSPSVSRASTLSVSGWASFSASGAS 335
Query: 547 STAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVL 606
+ + + + H+ SG + D W P G S+ W++ WA S+
Sbjct: 336 APSDSGWTSHSASGVSTTSDSG--WASPSAS-----GASTSSDSGWASPSASWASPSA-- 386
Query: 607 GHLGDGKKNGSGWDADSNRSGS 628
G + SGW + S S
Sbjct: 387 --SGASTPSDSGWASPSASGAS 406
Score = 64.7 bits (156), Expect = 7e-10
Identities = 77/341 (22%), Positives = 125/341 (36%), Gaps = 53/341 (15%)
Query: 587 RSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNR-----SGSGWNDTTRSG---- 637
R++ + G WA SS+ G + SGW + S S SGW + SG
Sbjct: 8 RASGVSTPSGSGWASSSAS----GASTPSNSGWASPSASGASIPSDSGWASPSASGASTP 63
Query: 638 -NSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGP 696
NSGW + + + A+ ++ G P +WAS P D+ ++ + + + +GW
Sbjct: 64 SNSGWASFSASWASIPSDSGWA---SPSASWASTPSDSGWASPSASGASIPSDSGWAS-- 118
Query: 697 VPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSST 756
P S + W PS + S W PS T + +P ++
Sbjct: 119 -PSVSGASIPSAFWASPSASGASTPSD-----SGWASPSASWASTSSDSGWASPSASWTS 172
Query: 757 TTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPVSSGWGEMPNVHSKTENSWGE 816
+ + +++ + ++T P + S P GW P+ ++ W
Sbjct: 173 PSASCASSSASGASTPSDSGWASPSVFWVSPSTSWASSPSDFGWASTPS-----DSGWAS 227
Query: 817 PSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPVAASALCKPASKSMQEGW 876
S+ +A G SS SGW A P ++ S AS S GW
Sbjct: 228 SSASCI----SPSASGASTSSDSGW----ASPSASW--------VSTSTSRASTSSDSGW 271
Query: 877 GSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWGNAP 917
S S++ W+ D S SS +SW +AP
Sbjct: 272 AS-------SSASWDSITSDSGWVCPSASWASSSASWASAP 305
Score = 55.5 bits (132), Expect = 5e-07
Identities = 92/409 (22%), Positives = 147/409 (35%), Gaps = 72/409 (17%)
Query: 1352 SPASPPVAVPHSWSRAKSDSDKISNGSSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSV 1411
SP++ ++P A + S S+ W W + + P + S
Sbjct: 38 SPSASGASIPSDSGWASPSASGASTPSNSGWASF---SASWASIPSDSGWASPSASWAST 94
Query: 1412 PTGPTINTTIQDVNRYLLKSGGSSPPSSQNATLPSSSAWPLSASGYSSSFSSIASAPSVA 1471
P+ G + PS+ A++PS S W + +S S+ ++PS +
Sbjct: 95 PS-----------------DSGWASPSASGASIPSDSGWASPSVSGASIPSAFWASPSAS 137
Query: 1472 GKLSDIKSTWSSGPTSHTQASLSHELWKVPRNS-TAP-------------TRPPPGLTNP 1517
G + S W+S P++ ++ S W P S T+P T G +P
Sbjct: 138 GASTPSDSGWAS-PSASWASTSSDSGWASPSASWTSPSASCASSSASGASTPSDSGWASP 196
Query: 1518 -----KPSSTWGASP--LGWTS-------SYSSGSAWSTDTSGRTSS----WLVLRNLTP 1559
PS++W +SP GW S + SS S S SG ++S W
Sbjct: 197 SVFWVSPSTSWASSPSDFGWASTPSDSGWASSSASCISPSASGASTSSDSGW--ASPSAS 254
Query: 1560 QIDGSTLRTLCLQHGPLITFHL---NLTQGNAVVRYSSKEEAAKAQKSLHMCVLGNTTIL 1616
+ ST R + ++T + V S+ ++ A + G+++
Sbjct: 255 WVSTSTSRASTSSDSGWASSSASWDSITSDSGWVCPSASWASSSASWASAPSDSGSSSPS 314
Query: 1617 AEFAGEEEVN---RFLAQGQALPPTSSWQSSSASSQPRLSAAG----SSHGLVRSDAGHW 1669
A V+ F A G + P S W S SAS S +G S+ G S W
Sbjct: 315 VSRASTLSVSGWASFSASGASAPSDSGWTSHSASGVSTTSDSGWASPSASGASTSSDSGW 374
Query: 1670 NAPCLGGKGSSELLWGGVPQYSSSLWGPPSADDSRVIGSPTPLTTLLPG 1718
+P S G S S W PSA + + +P +L PG
Sbjct: 375 ASPSASWASPSA---SGASTPSDSGWASPSASGASMPSAP----SLCPG 416
Score = 49.7 bits (117), Expect = 2e-05
Identities = 86/403 (21%), Positives = 156/403 (38%), Gaps = 52/403 (12%)
Query: 20 NNGTNGALVQSPSNQSALGAGGAN----SNGSAARVWGVATGSSSGLAHCSVSGGDGKMD 75
++ +GA S S ++ A GA+ S ++ G +T S+SG A S S D
Sbjct: 22 SSSASGASTPSNSGWASPSASGASIPSDSGWASPSASGASTPSNSGWASFSASWASIPSD 81
Query: 76 TMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPV-LGHEGTVATGN--PSSICSPVSA 132
+ G W ++ S++G +P+A+ A+ P G +G PS+ + SA
Sbjct: 82 S--GWASPSASWASTPSDSGW---ASPSASGASIPSDSGWASPSVSGASIPSAFWASPSA 136
Query: 133 IGQNMGNQNG--------NPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLNTDGP 184
G + + +G T + W + ++ + S + S ++ P + P
Sbjct: 137 SGASTPSDSGWASPSASWASTSSDSGWASPSASWTSPSASCASSSASGASTPSDSGWASP 196
Query: 185 N-----NTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGG 239
+ + SSP+ T W A + I P A+G+S S SG
Sbjct: 197 SVFWVSPSTSWASSPSDFGWASTPSDSGW--ASSSASCISP------SASGASTSSDSGW 248
Query: 240 SAEGISNSVWGLSPGNPATGNSNSGF--SQGNGDTVNSALSAKQNGSSSAVQKEGSGGNA 297
++ S W + + A+ +S+SG+ S + D++ S +G S +
Sbjct: 249 ASPSAS---WVSTSTSRASTSSDSGWASSSASWDSITS-----DSGWVCPSASWASSSAS 300
Query: 298 WDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDING 357
W S P GS + V + + + +++G + HS S ++
Sbjct: 301 WASAPSDS--------GSSSPSVSRASTLSVSGWASFSASGASAPSDSGWTSHSASGVST 352
Query: 358 KGSTGWESPSVTSQNPTVQPG-GEHMNSWAKAASSGTTASEGS 399
+GW SPS + + + G SWA ++SG + S
Sbjct: 353 TSDSGWASPSASGASTSSDSGWASPSASWASPSASGASTPSDS 395
Score = 48.1 bits (113), Expect = 7e-05
Identities = 71/328 (21%), Positives = 111/328 (33%), Gaps = 78/328 (23%)
Query: 623 SNRSGSGWNDTTRSG-----NSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVS 677
S SGSGW ++ SG NSGW + + + A+ ++ G P + AS P ++ +
Sbjct: 13 STPSGSGWASSSASGASTPSNSGWASPSASGASIPSDSGWA---SPSASGASTPSNSGWA 69
Query: 678 NWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNY 737
++ + + + +GW S +GW PS + S W PS
Sbjct: 70 SFSASWASIPSDSGWASPSASWASTPSD--SGWASPSASGASIPSD-----SGWASPS-- 120
Query: 738 NNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPVS 797
+ ++ + + + + +T P
Sbjct: 121 --------------VSGASIPSAFWASPSASGAST----------------------PSD 144
Query: 798 SGWGEMPNVHSKT--ENSWGEPS----SPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVA 851
SGW + T ++ W PS SPS + +A+ PS SGW A P V
Sbjct: 145 SGWASPSASWASTSSDSGWASPSASWTSPSASCASSSASGASTPSD-SGW----ASPSVF 199
Query: 852 FGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCS 911
+ S AS GW S S S W + +AS STSS S
Sbjct: 200 W--------VSPSTSWASSPSDFGWAS-----TPSDSGWASSSASCISPSASGASTSSDS 246
Query: 912 SWGNAPKKGLQKG-MKTSGKQDEAWIMS 938
W + + + S D W S
Sbjct: 247 GWASPSASWVSTSTSRASTSSDSGWASS 274
Score = 43.9 bits (102), Expect = 0.001
Identities = 72/279 (25%), Positives = 117/279 (41%), Gaps = 67/279 (24%)
Query: 1431 SGGSSPPSSQNATLPSSSAWPLSASGYSSSFSSIASAPSVAGKLSDIKSTWSSGPTSHTQ 1490
SG S+P S A+ +S A S SG++S +S AS PS +G S ++ +S P++
Sbjct: 10 SGVSTPSGSGWASSSASGASTPSNSGWASPSASGASIPSDSGWASP-SASGASTPSNSGW 68
Query: 1491 ASLSHELWKVPRNSTAPTRPPPGLTNPKPSSTWGASPL--GWTSSYSSGSAWSTDTSGRT 1548
AS S +P +S + PS++W ++P GW S +SG++ +D
Sbjct: 69 ASFSASWASIPSDSGWAS----------PSASWASTPSDSGWASPSASGASIPSD----- 113
Query: 1549 SSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKAQKSLHMC 1608
S W +P + G+++ + F + + A S+ ++ A S
Sbjct: 114 SGW-----ASPSVSGASIPS---------AFWASPSASGA----STPSDSGWASPS---- 151
Query: 1609 VLGNTTILAEFAGEEEVNRFLAQGQALPPTSSWQSSSASSQPRLSAAGSSHGLVRSDAG- 1667
A +A + + + P++SW S SAS SA+G+S SD+G
Sbjct: 152 --------ASWASTSSDSGWAS------PSASWTSPSASCASS-SASGAS---TPSDSGW 193
Query: 1668 -----HWNAPCLGGKGS-SELLWGGVPQYSSSLWGPPSA 1700
W +P S S+ W P S S W SA
Sbjct: 194 ASPSVFWVSPSTSWASSPSDFGWASTP--SDSGWASSSA 230
Score = 41.6 bits (96), Expect = 0.007
Identities = 76/309 (24%), Positives = 117/309 (37%), Gaps = 53/309 (17%)
Query: 1254 SSPNTFAPYPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMDNLPS---AA 1310
SS + +A + +P+ + S +G + D W P+ PS A+
Sbjct: 158 SSDSGWASPSASWTSPSASCASSSASGASTPSDSG--------WASPSVFWVSPSTSWAS 209
Query: 1311 SPLE----QNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVA--VPHSW 1364
SP + PS G S P S S S+S + P A V S
Sbjct: 210 SPSDFGWASTPSDSGWASSSASCISPSASGASTS---------SDSGWASPSASWVSTST 260
Query: 1365 SRAKSDSDKISNGSSINWPPEFH------PGVPWKGLQNIDPENDPDVTPGSVPTGPTIN 1418
SRA + SD SS +W P W + + P + S P+ +
Sbjct: 261 SRASTSSDSGWASSSASWDSITSDSGWVCPSASWAS-SSASWASAPSDSGSSSPSVSRAS 319
Query: 1419 TTIQDVNRYLLKSGGSSPPSSQNATLPSSSAWPL-SASGYSSSFSSIASAPSVAGKLSDI 1477
T L G + S+ A+ PS S W SASG S++ S ++PS +G +
Sbjct: 320 T---------LSVSGWASFSASGASAPSDSGWTSHSASGVSTTSDSGWASPSASGASTSS 370
Query: 1478 KSTWSS------GPTSHTQASLSHELWKVPRNSTA--PTRPP--PGLTNPKPSSTWGASP 1527
S W+S P++ ++ S W P S A P+ P PG P+ ++ G +
Sbjct: 371 DSGWASPSASWASPSASGASTPSDSGWASPSASGASMPSAPSLCPGSCFPQLTARTGFTV 430
Query: 1528 LGWTSSYSS 1536
+G+ S S
Sbjct: 431 VGFPFSLLS 439
Score = 34.3 bits (77), Expect = 1.1
Identities = 28/84 (33%), Positives = 35/84 (41%), Gaps = 16/84 (19%)
Query: 1630 AQGQALPPTSSWQSSSASSQPRLSAAG-----SSHGLVRSDAGHWNAPCLGGK------- 1677
A G + P S W SSSAS S +G +S + SD+G W +P G
Sbjct: 9 ASGVSTPSGSGWASSSASGASTPSNSGWASPSASGASIPSDSG-WASPSASGASTPSNSG 67
Query: 1678 -GSSELLWGGVPQYSSSLWGPPSA 1700
S W +P S S W PSA
Sbjct: 68 WASFSASWASIP--SDSGWASPSA 89
Score = 32.0 bits (71), Expect = 5.3
Identities = 57/262 (21%), Positives = 95/262 (36%), Gaps = 36/262 (13%)
Query: 53 GVATGSSSGLAHCSV-------SGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNAN 105
G +T S SG A SV S D S + W +S+++ ++P+A+
Sbjct: 184 GASTPSDSGWASPSVFWVSPSTSWASSPSDFGWASTPSDSGWASSSASC-----ISPSAS 238
Query: 106 PAAWPVLGHEGTVATGNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTS 165
A+ T + S SP SA + + + G W + S + TS
Sbjct: 239 GAS-----------TSSDSGWASP-SASWVSTSTSRASTSSDSG-WAS--SSASWDSITS 283
Query: 166 TSQNVSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGL 225
S V SA + + + + SS ++ T + W GA
Sbjct: 284 DSGWVCPSASWASSSASWASAPSDSGSSSPSVSRASTLSVSGWASFSASGA-------SA 336
Query: 226 PGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSS 285
P +G + SG S S+S W + A+ +S+SG++ + + + S S
Sbjct: 337 PSDSGWTSHSASGVSTT--SDSGWASPSASGASTSSDSGWASPSASWASPSASGASTPSD 394
Query: 286 SAVQKEGSGGNAWDSGPPAGPG 307
S + G + S P PG
Sbjct: 395 SGWASPSASGASMPSAPSLCPG 416
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 70.5 bits (171), Expect = 1e-11
Identities = 111/475 (23%), Positives = 169/475 (35%), Gaps = 56/475 (11%)
Query: 1046 PSQALGGIAS-GLGMQNLNSSRQIPSGNLGMFGNSGA----AQARTMQQPPQPPVQPLNS 1100
P Q+LGG+ S G Q ++ S Q P G GM +S A A +T Q Q +Q
Sbjct: 106 PGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQ 165
Query: 1101 SQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPINPQHMTMLNQLYQLQLAYQR 1160
Q + Q Q Q Q QF A+ S + Q ++ Q QLQ Q+
Sbjct: 166 QQQFQQQQQAALQQQQQQQQQQQFQAQQ---------SAMQQQFQAVVQQQQQLQ---QQ 213
Query: 1161 LQIQQQMLQAQRNVSGSMRQQEQQ---VARTITNLQQQIQQHQRQLAQALLVKQPP---- 1213
Q QQ +++ ++QQ+QQ +A+ QQQ QQ Q+Q Q L QPP
Sbjct: 214 QQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQP 273
Query: 1214 ---PPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPN 1270
P PPP +L + P P P + + P PL
Sbjct: 274 PMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVS---- 329
Query: 1271 MNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKHGAIPGGLSIG 1330
+ + G + P R P + P ++Q + +
Sbjct: 330 ---QAQALPGQMLYTQPPLKFVRAPM------VVQQPPVQPQVQQQQTAVQTAQAAQMVA 380
Query: 1331 PPGKSSIDDSYGRYDLIQNSESPASPPV-AVPHSWSRAKSDSDKISNGSSINWPPEFHPG 1389
PG I ++ + + + P + V A+P S + SS+ PG
Sbjct: 381 -PGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPG 439
Query: 1390 VPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSGGSSPPSSQNATLPSSSA 1449
+ Q++ P P PG + P N + S P S ++ LPS S
Sbjct: 440 QQVQTPQSMPPPPQPSPQPGQPSSQPNSNVS-------------SGPAPSPSSFLPSPSP 486
Query: 1450 WPLSASGYSSSFSSIASAPSVAGKLSDIKSTWSSGPTSHTQASLSHELWKVPRNS 1504
P S S ++ S PS + + + P +QA L K+ + S
Sbjct: 487 QP-SQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLS 540
Score = 33.1 bits (74), Expect = 2.4
Identities = 47/212 (22%), Positives = 79/212 (37%), Gaps = 43/212 (20%)
Query: 1043 SALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFGNSGAAQA----RTMQQPPQPPVQPL 1098
SA+PS ++ LG Q + Q+ +L M + Q ++M PPQP QP
Sbjct: 408 SAIPSSSIP-----LGRQPM---AQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPG 459
Query: 1099 N-SSQPSLRAQVPQFLSPQV----------QAQLLQFAAKNIGL-NPALLTSPINP---- 1142
SSQP+ SP Q+ + +N + +P L +P+NP
Sbjct: 460 QPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVM 519
Query: 1143 --------QHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQV-------AR 1187
+ L++L QL + L+ + + + + + + R
Sbjct: 520 SPAGSSQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKR 579
Query: 1188 TITNLQQQIQQHQRQLAQALLVKQPPPPPPPP 1219
Q+ + +L + V PPPPP PP
Sbjct: 580 CPLKTLQKCEIALEKLKNDMAVPTPPPPPVPP 611
>gi|161016767 mucin 21 [Homo sapiens]
Length = 566
Score = 68.2 bits (165), Expect = 7e-11
Identities = 120/521 (23%), Positives = 197/521 (37%), Gaps = 66/521 (12%)
Query: 137 MGNQNGNPTGTLGAWGNLLPQEST--EPQTSTSQNVSFSAQPQNLNTDGPNNTNPMNSSP 194
M Q GN L +G LL E+ +TSTS N S +T N+ + + SS
Sbjct: 1 MKMQKGN---VLLMFGLLLHLEAATNSNETSTSANTGSSVISSGAST-ATNSGSSVTSSG 56
Query: 195 NPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGG-SAEGISNSVWGLSP 253
+ + + + G+++ + G+ A S S VS G S S S S
Sbjct: 57 VSTATISGSSVTSNGVSIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSG 116
Query: 254 GNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGR 313
+ AT + +S S G NS S +G+S+A + S ++ S
Sbjct: 117 ASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEAS------------- 163
Query: 314 GSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNP 373
+ N + S + S S+ V+ N S++ +G ST S S T+ N
Sbjct: 164 -TATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSG-ASTATNSESRTTSNG 221
Query: 374 TVQPGGEHMNSWAKAASSGTTASEGS-----SDGSG--NHNEGSTGREGTGEGRRRDKGI 426
G NS + SSG + + S S G+G ++E ST G G +
Sbjct: 222 A----GTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESST 277
Query: 427 IDQGHIQLPRNDLDPRVLSNTGWGQTPVK-QNTAWEFEESPRSERKN-----DNGTEAWG 480
+ G + ++ TP NTA E S S N D+ T + G
Sbjct: 278 VSSGISTVTNSE-----------SSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSG 326
Query: 481 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDS 540
+ S S + G+ ST T+S S + A+ N+G +++ + +
Sbjct: 327 ASTATNSESSTTSSGA---STATNSESS-TTSSGASTATNSGSSTTSSGTSTATNSESST 382
Query: 541 ISSTAVSTAAAAKSGHAWSGAA---NQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGG 597
+SS A STA ++S SGA+ N E + + G S+ + S+G
Sbjct: 383 VSSGA-STATTSESSTTSSGASTATNSESSTVSSGASTATNSE--------SSTTSSGAN 433
Query: 598 DWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGN 638
+S S + G G +G S+ + + ++ G+
Sbjct: 434 TATNSGSSVTSAGSGTAALTGMHTTSHSASTAVSEAKPGGS 474
Score = 58.9 bits (141), Expect = 4e-08
Identities = 94/433 (21%), Positives = 162/433 (37%), Gaps = 42/433 (9%)
Query: 17 TNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGLAHCSVSGGDGKMDT 76
TN N + A + S+ + GA A ++GS+ GV+T + SG + S G +
Sbjct: 22 TNSNETSTSA--NTGSSVISSGASTATNSGSSVTSSGVSTATISGSS--VTSNGVSIVTN 77
Query: 77 MIGDGRSQNCWGASNS-----NAGINLNLNPNANPAAWPVLGHEGTVATGNPSSICSPVS 131
S A+NS ++GI++ N ++ + + AT + SS S
Sbjct: 78 SEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTS-----SGASTATNSESSTPSS-- 130
Query: 132 AIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLNTDGPNNTNPMN 191
G + + + T + GA +T +ST+ + + +A +T + N
Sbjct: 131 --GASTATNSDSSTTSSGA------STATNSDSSTTSSEASTATNSESSTTSSGASTATN 182
Query: 192 SSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGS-------SVSQVSGGSAEGI 244
S + +++ + + GA + + +NG+ S + SG S
Sbjct: 183 SESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATN 242
Query: 245 SNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPPA 304
S S S AT + +S S G G NS S +G S+ E S + SG
Sbjct: 243 SESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPS---SGANT 299
Query: 305 GPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSD---INGKGST 361
+ SG N N S + + +N + + +NS+ + ST
Sbjct: 300 ATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGAST 359
Query: 362 GWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSG----NHNEGSTGREGTG 417
S S T+ + T ++ + AS+ TT SE S+ SG ++E ST G
Sbjct: 360 ATNSGSSTTSSGTSTATNSESSTVSSGASTATT-SESSTTSSGASTATNSESSTVSSGAS 418
Query: 418 EGRRRDKGIIDQG 430
+ G
Sbjct: 419 TATNSESSTTSSG 431
Score = 55.1 bits (131), Expect = 6e-07
Identities = 100/429 (23%), Positives = 164/429 (38%), Gaps = 61/429 (14%)
Query: 315 SGNNGVGNIHSGA---WGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVT-S 370
S N G I SGA S TS+GV S + I+G T VT S
Sbjct: 30 SANTGSSVISSGASTATNSGSSVTSSGV-----------STATISGSSVTSNGVSIVTNS 78
Query: 371 QNPTVQPG-GEHMNSWAKAASSG---TTASEGSSDGSG----NHNEGSTGREGTGEGRRR 422
+ T G NS SSG T SE S+ SG ++E ST G
Sbjct: 79 EFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNS 138
Query: 423 DKGIIDQGHIQLPRNDL-----DPRVLSNTGWGQTPVKQNTAWEFEESPRSERKN---DN 474
D G +D + +N+ T +TA E S S R + ++
Sbjct: 139 DSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNS 198
Query: 475 GTEAWGCAATQASNSGGKND----GSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKA 530
+ A+ A+NS + G+ NS ++++ SG A+T ++
Sbjct: 199 ESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSG----------ASTATNSESSTP 248
Query: 531 PSGPGVWGDSISSTAVS---TAAAAKSGHAWSG---AANQEDKSPTWGEPPKPKSQHWGD 584
SG G +S SST S TA ++S SG N E +P+ G S+
Sbjct: 249 SSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTT 308
Query: 585 GQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSG----WDADSNRSGSGWNDTTRSGNSG 640
+N A ++ + +S + + SG +++S+ + SG + T SG+S
Sbjct: 309 SSGANTATNSDSSTTSSGASTATN-SESSTTSSGASTATNSESSTTSSGASTATNSGSST 367
Query: 641 WGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVK 700
+ T+T N ++ T+ G + A+ + + S+ A+ ++ T G
Sbjct: 368 TSSGTSTATNSESS---TVSSG--ASTATTSESSTTSSGASTATNSESSTVSSGASTATN 422
Query: 701 QKDSSEATG 709
+ S+ ++G
Sbjct: 423 SESSTTSSG 431
Score = 50.1 bits (118), Expect = 2e-05
Identities = 76/363 (20%), Positives = 131/363 (36%), Gaps = 43/363 (11%)
Query: 493 NDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAA 552
N S S+ S+ + ++ P++ A+T ++ SG +S SST S A+ A
Sbjct: 107 NSESSTTSSGASTATNSESSTPSS-GASTATNSDSSTTSSGASTATNSDSSTTSSEASTA 165
Query: 553 KSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDG 612
+ S + + T E S+ + S+G +S S G G
Sbjct: 166 TNSE--SSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAG 223
Query: 613 KKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTK-------ANPGTNW---------- 655
S S+ + + N + + +SG G +TN++ A TN
Sbjct: 224 TATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGIS 283
Query: 656 ----GETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWE 711
E+ P N A+ + + S+ A+ + T G + S+ ++G
Sbjct: 284 TVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSG-- 341
Query: 712 EPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNT 771
S E +S +N + T + +SST ++ +T TT+ S+T
Sbjct: 342 ----ASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESST 397
Query: 772 THRVETPPPHQAGTQLNRSPLLGPVSSGWGEMPNVHSKTENSWGEPSSPS----TLVDNG 827
T +G + VSSG N S T +S ++ S T +G
Sbjct: 398 T---------SSGASTATNSESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSG 448
Query: 828 TAA 830
TAA
Sbjct: 449 TAA 451
Score = 47.8 bits (112), Expect = 9e-05
Identities = 62/306 (20%), Positives = 128/306 (41%), Gaps = 28/306 (9%)
Query: 2 ATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSG 61
+T S++ + +++ + ++G + A S S ++ GAG A ++ S+ G +T ++S
Sbjct: 186 STVSSRASTATNSESSTTSSGASTA-TNSESRTTSNGAGTATNSESSTTSSGASTATNSE 244
Query: 62 LAHCSVSGGDG----KMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGT 117
+ S G T G G + N ++ S+ + + ++ P++
Sbjct: 245 SSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSG------AN 298
Query: 118 VATGNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQ 177
AT + SS S G N + + T + GA +T ++ST+ + + +A
Sbjct: 299 TATNSESSTTSS----GANTATNSDSSTTSSGA------STATNSESSTTSSGASTATNS 348
Query: 178 NLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSV---- 233
+T + NS + ++ + + V GA + ++G+S
Sbjct: 349 ESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNS 408
Query: 234 --SQVSGGSAEGISNSVWGLSPG-NPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQK 290
S VS G++ ++ S G N AT + +S S G+G + + + +S+AV +
Sbjct: 409 ESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSASTAVSE 468
Query: 291 EGSGGN 296
GG+
Sbjct: 469 AKPGGS 474
Score = 35.0 bits (79), Expect = 0.63
Identities = 56/293 (19%), Positives = 101/293 (34%), Gaps = 21/293 (7%)
Query: 724 IDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNT-THRVETPPPHQ 782
I T++ ++ T + + P +ST TN+ ++TT++ ++T T+ + +
Sbjct: 102 ISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSE 161
Query: 783 AGTQLNRSPLLGPVSSGWGEMPNVHSKTENSW------GEPSSPSTLVDNGTAAWGKPPS 836
A T N SSG N S T +S E S+ S+ T + + S
Sbjct: 162 ASTATNSES--STTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTS 219
Query: 837 SGSGWGDHPAEPPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGD 896
+G+G + + G AS S + G G+ + + +TS
Sbjct: 220 NGAGTATNSESSTTSSG-------ASTATNSESSTPSSGAGTATNSESSTTS----SGAG 268
Query: 897 VWNNAASQESTSSCSSWGNAPKKGLQKGMKTSGKQDEAWIMSRL-IKQLTDMGFPREPAE 955
N+ S +S S+ N+ G T+ + + S +D A
Sbjct: 269 TATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGAS 328
Query: 956 EALKSNNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPLGCRPPISKESS 1008
A S + S + G ++G + G + ESS
Sbjct: 329 TATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESS 381
Score = 34.7 bits (78), Expect = 0.83
Identities = 48/184 (26%), Positives = 78/184 (42%), Gaps = 29/184 (15%)
Query: 1369 SDSDKISNGSSINWPPEFHPGVPWKGLQNIDPENDPDVTPG-SVPTGPTINTTIQDVNRY 1427
S S SNG SI EFH G+ V+ G S+ T +TT
Sbjct: 63 SGSSVTSNGVSIVTNSEFH--TTSSGISTATNSEFSTVSSGISIATNSESSTT------- 113
Query: 1428 LLKSGGSSPPSSQNATLPSSSAWPLSASGYSSSFSSIASAPSVAGKLSDIKSTWSSGPT- 1486
S G+S ++ ++ PSS AS ++S SS S+ + SD +T S T
Sbjct: 114 ---SSGASTATNSESSTPSS-----GASTATNSDSSTTSSGASTATNSDSSTTSSEASTA 165
Query: 1487 SHTQASLSHELWKVPRNSTAPTRPPPGLTNPKPSSTWGASPLGWTSSYSSGSAWSTDTSG 1546
+++++S + NS + T SS + +S+ SSG++ +T++
Sbjct: 166 TNSESSTTSSGASTATNSESST----------VSSRASTATNSESSTTSSGASTATNSES 215
Query: 1547 RTSS 1550
RT+S
Sbjct: 216 RTTS 219
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 66.6 bits (161), Expect = 2e-10
Identities = 95/410 (23%), Positives = 145/410 (35%), Gaps = 40/410 (9%)
Query: 1046 PSQALGGIAS-GLGMQNLNSSRQIPSGNLGMFGNSGA----AQARTMQQPPQPPVQPLNS 1100
P Q+LGG+ S G Q ++ S Q P G GM +S A A +T Q Q +Q
Sbjct: 106 PGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQ 165
Query: 1101 SQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPINPQHMTMLNQLYQLQLAYQR 1160
Q + Q Q Q Q QF A+ S + Q ++ Q QLQ Q+
Sbjct: 166 QQQFQQQQQAALQQQQQQQQQQQFQAQQ---------SAMQQQFQAVVQQQQQLQ---QQ 213
Query: 1161 LQIQQQMLQAQRNVSGSMRQQEQQ---VARTITNLQQQIQQHQRQLAQALLVKQPP---- 1213
Q QQ +++ ++QQ+QQ +A+ QQQ QQ Q+Q Q L QPP
Sbjct: 214 QQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQP 273
Query: 1214 ---PPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPN 1270
P PPP +L + P P P + + P PL
Sbjct: 274 PMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVS---- 329
Query: 1271 MNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKHGAIPGGLSIG 1330
+ + G + P R P + Q + G+ +
Sbjct: 330 ---QAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVS 386
Query: 1331 PPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSDSDKISNGSSINWPPEFHPGV 1390
+ S +Q +S PP P + + +S+G + + P F P
Sbjct: 387 QSSLPML-SSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPS-PSSFLPSP 444
Query: 1391 PWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSGGSSPPSSQ 1440
+ Q+ P SVP+ +NT + + ++ GSS Q
Sbjct: 445 SPQPSQSPVTARTPQ--NFSVPSPGPLNTPVNPSS--VMSPAGSSQAEEQ 490
Score = 42.0 bits (97), Expect = 0.005
Identities = 51/210 (24%), Positives = 80/210 (38%), Gaps = 12/210 (5%)
Query: 1088 QQPPQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPINPQHMTM 1147
Q PPQP P+ +QPS Q+P PQ Q Q L A+ + P+ M
Sbjct: 300 QPPPQPQQPPVAQNQPS---QLP----PQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPM 352
Query: 1148 LNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTIT-NLQQQIQQHQRQLAQA 1206
+ Q +Q Q+ Q Q QA + V+ ++ + + + + QQ+Q Q
Sbjct: 353 VVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPP 412
Query: 1207 LLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFAPYPLAG 1266
QP P P P + + S S +P Q+ +P F+
Sbjct: 413 ----QPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGP 468
Query: 1267 LNPNMNVNSMDMTGGLSVKDPSQSQSRLPQ 1296
LN +N +S+ G S + Q +L Q
Sbjct: 469 LNTPVNPSSVMSPAGSSQAEEQQYLDKLKQ 498
Score = 31.2 bits (69), Expect = 9.1
Identities = 40/188 (21%), Positives = 68/188 (36%), Gaps = 35/188 (18%)
Query: 1067 QIPSGNLGMFGNSGAAQA----RTMQQPPQPPVQPLN-SSQPSLRAQVPQFLSPQV---- 1117
Q+ +L M + Q ++M PPQP QP SSQP+ SP
Sbjct: 384 QVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPS 443
Query: 1118 ------QAQLLQFAAKNIGL-NPALLTSPINP------------QHMTMLNQLYQLQLAY 1158
Q+ + +N + +P L +P+NP + L++L QL
Sbjct: 444 PSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYI 503
Query: 1159 QRLQIQQQMLQAQRNVSGSMRQQEQQV-------ARTITNLQQQIQQHQRQLAQALLVKQ 1211
+ L+ + + + + + + R Q+ + +L + V
Sbjct: 504 EPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMAVPT 563
Query: 1212 PPPPPPPP 1219
PPPPP PP
Sbjct: 564 PPPPPVPP 571
>gi|186928827 dermokine isoform 5 precursor [Homo sapiens]
Length = 398
Score = 60.1 bits (144), Expect = 2e-08
Identities = 67/233 (28%), Positives = 89/233 (38%), Gaps = 24/233 (10%)
Query: 223 QGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNS-GFSQGNGDTVNSALSAKQ 281
QG+PG NG+ + SGG GI S GL G GN G +G NSA S
Sbjct: 133 QGVPGHNGAW--ETSGG--HGIFGSQGGL--GGQGQGNPGGLGTPWVHGYPGNSAGSFGM 186
Query: 282 NGSSSAVQKEGSGG----NAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSN 337
N + + G+GG G A PG + + N G N G S ++
Sbjct: 187 NPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGG 246
Query: 338 GVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASE 397
G + G + + + NG S G S S + + GG NS SG+ +S
Sbjct: 247 GSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSW 306
Query: 398 GSSDGSGNHNEGST-------------GREGTGEGRRRDKGIIDQGHIQLPRN 437
GSS GS + N G + G E G G +G QG RN
Sbjct: 307 GSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMRN 359
Score = 52.8 bits (125), Expect = 3e-06
Identities = 94/387 (24%), Positives = 130/387 (33%), Gaps = 61/387 (15%)
Query: 2 ATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGA-NSNGSAARVWGVATGSSS 60
+TG+ G GH G AL + AGGA S S A G +
Sbjct: 30 STGTNIGEALGH--------GLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGT 81
Query: 61 GLAHCSVSGGDGKMDTMIGDGRSQ--NCWGASNSNAGINLNLNPNANPAAWP-VLGHEGT 117
G+ G + +G+ N A + +A +W V GH G
Sbjct: 82 GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGA 141
Query: 118 VATGNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQ 177
T I +G G GNP G W + P S SF PQ
Sbjct: 142 WETSGGHGIFGSQGGLG---GQGQGNPGGLGTPWVHGYPGNSAG---------SFGMNPQ 189
Query: 178 NLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMA-VGMGAIIPPHLQGLPGANGS----- 231
N P N N A+ G + + G PP G++ S
Sbjct: 190 GAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG 249
Query: 232 SVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKE 291
S S SG + G +N+ G S G ++G+S+ G S G SS
Sbjct: 250 SQSGSSGSGSNGDNNN--GSSSGGSSSGSSSGGSS----------------GGSSGGSSG 291
Query: 292 GSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHS 351
SGG+ DSG + +WG +G++ GN H G+ G NG KP N+
Sbjct: 292 NSGGSRGDSGSES-----SWGSSTGSSS-GN-HGGSGG------GNGHKPGCEKPGNEAR 338
Query: 352 NSDINGKGSTGWESPSVTSQNPTVQPG 378
S +G + S +N PG
Sbjct: 339 GSGESGIQGFRGQGVSSNMRNSETSPG 365
Score = 48.1 bits (113), Expect = 7e-05
Identities = 53/233 (22%), Positives = 86/233 (36%), Gaps = 33/233 (14%)
Query: 509 WVNAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKS 568
WV+ P + G AP G G G + + A A+ G+ A+NQ +
Sbjct: 172 WVHGYPGNSAGSFGMNPQG--APWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGC 229
Query: 569 PTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGS 628
+NP S GG ++S G +GS D ++ S
Sbjct: 230 -------------------TNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSG 270
Query: 629 GWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQT 688
G + + SG S G+S + N G + G++ G + +W S G++S
Sbjct: 271 GSSSGSSSGGSSGGSSGGSSGNSGGSRGDS---GSESSWGSST---------GSSSGNHG 318
Query: 689 GTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKT 741
G+G G P +K +EA G E R + + ++ P +N T
Sbjct: 319 GSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMRNSETSPGMFNFDT 371
Score = 41.6 bits (96), Expect = 0.007
Identities = 83/318 (26%), Positives = 114/318 (35%), Gaps = 72/318 (22%)
Query: 223 QGLPGANGSSVSQVSG-GSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQ 281
QG A G+ V QV G G+A+ + N V A GN+ + D + A +
Sbjct: 73 QGTREAVGTGVRQVPGFGAADALGNRV---GEAAHALGNTGHEIGRQAEDVIRHGADAVR 129
Query: 282 NGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNG 341
GS V G G AW++ G GI G G G GN G G P V+G
Sbjct: 130 -GSWQGVP--GHNG-AWETS--GGHGIFGSQGGLGGQGQGN--PGGLGTP------WVHG 175
Query: 342 EWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAK---AASSGTTASEG 398
G N GS G NP P G+ N + G A G
Sbjct: 176 YPG-----------NSAGSFG--------MNPQGAPWGQGGNGGPPNFGTNTQGAVAQPG 216
Query: 399 -SSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQN 457
S + N NEG T +G G SN+G G +
Sbjct: 217 YGSVRASNQNEGCTNPPPSGSGGGS----------------------SNSGGGSGSQSGS 254
Query: 458 TAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAV 517
+ S N+NG+ + G ++ S+SGG + GS S+ S S + ++
Sbjct: 255 SG------SGSNGDNNNGSSSGG--SSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSW 306
Query: 518 PANTGWGDSNNKAPSGPG 535
++TG S N SG G
Sbjct: 307 GSSTG-SSSGNHGGSGGG 323
Score = 38.9 bits (89), Expect = 0.044
Identities = 33/131 (25%), Positives = 52/131 (39%), Gaps = 14/131 (10%)
Query: 793 LGPVSSGWGE-----MPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAE 847
+ P + WG+ PN + T+ + +P S N PP SGSG G +
Sbjct: 186 MNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSG 245
Query: 848 PPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLST--SQWEDEEGDVWNNAASQE 905
G +G+ +S ++ G SGG S+ S G N+ S+
Sbjct: 246 -----GGSGSQSGSSG--SGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRG 298
Query: 906 STSSCSSWGNA 916
+ S SSWG++
Sbjct: 299 DSGSESSWGSS 309
>gi|186928829 dermokine isoform 4 precursor [Homo sapiens]
Length = 386
Score = 59.7 bits (143), Expect = 2e-08
Identities = 59/195 (30%), Positives = 80/195 (41%), Gaps = 11/195 (5%)
Query: 223 QGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNS-GFSQGNGDTVNSALSAKQ 281
QG+PG NG+ + SGG GI S GL G GN G +G NSA S
Sbjct: 133 QGVPGHNGAW--ETSGG--HGIFGSQGGL--GGQGQGNPGGLGTPWVHGYPGNSAGSFGM 186
Query: 282 NGSSSAVQKEGSGG----NAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSN 337
N + + G+GG G A PG + + N G N G S ++
Sbjct: 187 NPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGG 246
Query: 338 GVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASE 397
G + G + + + NG S G S S + + GG NS SG+ +S
Sbjct: 247 GSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSW 306
Query: 398 GSSDGSGNHNEGSTG 412
GSS GS + N G +G
Sbjct: 307 GSSTGSSSGNHGGSG 321
Score = 52.8 bits (125), Expect = 3e-06
Identities = 91/390 (23%), Positives = 122/390 (31%), Gaps = 79/390 (20%)
Query: 2 ATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGA-NSNGSAARVWGVATGSSS 60
+TG+ G GH G AL + AGGA S S A G +
Sbjct: 30 STGTNIGEALGH--------GLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGT 81
Query: 61 GLAHCSVSGGDGKMDTMIGDGRSQ--NCWGASNSNAGINLNLNPNANPAAWP-VLGHEGT 117
G+ G + +G+ N A + +A +W V GH G
Sbjct: 82 GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGA 141
Query: 118 VATGNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQ 177
T I +G G GNP G W + P S SF PQ
Sbjct: 142 WETSGGHGIFGSQGGLG---GQGQGNPGGLGTPWVHGYPGNSAG---------SFGMNPQ 189
Query: 178 NLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVS 237
N P N N GA+ P + +N +
Sbjct: 190 GAPWGQGGNGGPPNFGTNT-----------------QGAVAQPGYGSVRASNQN------ 226
Query: 238 GGSAEGISNSVWGLSPGNPATGNSNSGFSQG--NGDTVNSALSAKQNGSSSAVQKEGSGG 295
EG +N P G+SNSG G +G + + + NGSSS GS
Sbjct: 227 ----EGCTNP----PPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSS 278
Query: 296 NAWDSGPPAGPGILAWGRGSGNNGVGNIHSG---AWGHPSRSTSNGVNGEWG----KPPN 348
G G SGN+G SG +WG + S+S G G KP
Sbjct: 279 GGSSGGSSGG--------SSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGC 330
Query: 349 QHSNSDINGKGSTGWESPSVTSQNPTVQPG 378
+ ++ G G +G QN PG
Sbjct: 331 EKPGNEARGSGESG-------IQNSETSPG 353
Score = 47.8 bits (112), Expect = 9e-05
Identities = 48/201 (23%), Positives = 76/201 (37%), Gaps = 33/201 (16%)
Query: 509 WVNAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKS 568
WV+ P + G AP G G G + + A A+ G+ A+NQ +
Sbjct: 172 WVHGYPGNSAGSFGMNPQG--APWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGC 229
Query: 569 PTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGS 628
+NP S GG ++S G +GS D ++ S
Sbjct: 230 -------------------TNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSG 270
Query: 629 GWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQT 688
G + + SG S G+S + N G + G++ G + +W S G++S
Sbjct: 271 GSSSGSSSGGSSGGSSGGSSGNSGGSRGDS---GSESSWGSST---------GSSSGNHG 318
Query: 689 GTGWIGGPVPVKQKDSSEATG 709
G+G G P +K +EA G
Sbjct: 319 GSGGGNGHKPGCEKPGNEARG 339
Score = 41.6 bits (96), Expect = 0.007
Identities = 83/318 (26%), Positives = 114/318 (35%), Gaps = 72/318 (22%)
Query: 223 QGLPGANGSSVSQVSG-GSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQ 281
QG A G+ V QV G G+A+ + N V A GN+ + D + A +
Sbjct: 73 QGTREAVGTGVRQVPGFGAADALGNRV---GEAAHALGNTGHEIGRQAEDVIRHGADAVR 129
Query: 282 NGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNG 341
GS V G G AW++ G GI G G G GN G G P V+G
Sbjct: 130 -GSWQGVP--GHNG-AWETS--GGHGIFGSQGGLGGQGQGN--PGGLGTP------WVHG 175
Query: 342 EWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAK---AASSGTTASEG 398
G N GS G NP P G+ N + G A G
Sbjct: 176 YPG-----------NSAGSFG--------MNPQGAPWGQGGNGGPPNFGTNTQGAVAQPG 216
Query: 399 -SSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQN 457
S + N NEG T +G G SN+G G +
Sbjct: 217 YGSVRASNQNEGCTNPPPSGSGGGS----------------------SNSGGGSGSQSGS 254
Query: 458 TAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAV 517
+ S N+NG+ + G ++ S+SGG + GS S+ S S + ++
Sbjct: 255 SG------SGSNGDNNNGSSSGG--SSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSW 306
Query: 518 PANTGWGDSNNKAPSGPG 535
++TG S N SG G
Sbjct: 307 GSSTG-SSSGNHGGSGGG 323
Score = 38.9 bits (89), Expect = 0.044
Identities = 33/131 (25%), Positives = 52/131 (39%), Gaps = 14/131 (10%)
Query: 793 LGPVSSGWGE-----MPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAE 847
+ P + WG+ PN + T+ + +P S N PP SGSG G +
Sbjct: 186 MNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSG 245
Query: 848 PPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLST--SQWEDEEGDVWNNAASQE 905
G +G+ +S ++ G SGG S+ S G N+ S+
Sbjct: 246 -----GGSGSQSGSSG--SGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRG 298
Query: 906 STSSCSSWGNA 916
+ S SSWG++
Sbjct: 299 DSGSESSWGSS 309
>gi|186928825 dermokine isoform 3 precursor [Homo sapiens]
Length = 416
Score = 59.7 bits (143), Expect = 2e-08
Identities = 59/195 (30%), Positives = 80/195 (41%), Gaps = 11/195 (5%)
Query: 223 QGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNS-GFSQGNGDTVNSALSAKQ 281
QG+PG NG+ + SGG GI S GL G GN G +G NSA S
Sbjct: 133 QGVPGHNGAW--ETSGG--HGIFGSQGGL--GGQGQGNPGGLGTPWVHGYPGNSAGSFGM 186
Query: 282 NGSSSAVQKEGSGG----NAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSN 337
N + + G+GG G A PG + + N G N G S ++
Sbjct: 187 NPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGG 246
Query: 338 GVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASE 397
G + G + + + NG S G S S + + GG NS SG+ +S
Sbjct: 247 GSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSW 306
Query: 398 GSSDGSGNHNEGSTG 412
GSS GS + N G +G
Sbjct: 307 GSSTGSSSGNHGGSG 321
Score = 52.8 bits (125), Expect = 3e-06
Identities = 94/372 (25%), Positives = 128/372 (34%), Gaps = 41/372 (11%)
Query: 2 ATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGA-NSNGSAARVWGVATGSSS 60
+TG+ G GH G AL + AGGA S S A G +
Sbjct: 30 STGTNIGEALGH--------GLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGT 81
Query: 61 GLAHCSVSGGDGKMDTMIGDGRSQ--NCWGASNSNAGINLNLNPNANPAAWP-VLGHEGT 117
G+ G + +G+ N A + +A +W V GH G
Sbjct: 82 GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGA 141
Query: 118 VATGNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQ 177
T I +G G GNP G W + P S SF PQ
Sbjct: 142 WETSGGHGIFGSQGGLG---GQGQGNPGGLGTPWVHGYPGNSAG---------SFGMNPQ 189
Query: 178 NLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMA-VGMGAIIPPHLQGLPGANGS----- 231
N P N N A+ G + + G PP G++ S
Sbjct: 190 GAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG 249
Query: 232 SVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGN--GDTVNSALSAKQNGSSSA-- 287
S S SG + G +N+ G S G ++G+S+ G S G+ G + NS S +GS S+
Sbjct: 250 SQSGSSGSGSNGDNNN--GSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWG 307
Query: 288 VQKEGSGGNAWDSGPPAG--PGILAWG---RGSGNNGVGNIHSGAWGHPSRSTSNGVNGE 342
S GN SG G PG G RGSG +G+ R S N
Sbjct: 308 SSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRL 367
Query: 343 WGKPPNQHSNSD 354
G + + NS+
Sbjct: 368 LGGSGDNYRNSE 379
Score = 48.9 bits (115), Expect = 4e-05
Identities = 55/239 (23%), Positives = 86/239 (35%), Gaps = 41/239 (17%)
Query: 509 WVNAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKS 568
WV+ P + G AP G G G + + A A+ G+ A+NQ +
Sbjct: 172 WVHGYPGNSAGSFGMNPQG--APWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGC 229
Query: 569 PTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGS 628
+NP S GG ++S G +GS D ++ S
Sbjct: 230 -------------------TNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSG 270
Query: 629 GWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQT 688
G + + SG S G+S + N G + G++ G + +W S G++S
Sbjct: 271 GSSSGSSSGGSSGGSSGGSSGNSGGSRGDS---GSESSWGSST---------GSSSGNHG 318
Query: 689 GTGWIGGPVPVKQKDSSEATGWEEPSPPSIR--------RKMEIDDGTSAWGDPSNYNN 739
G+G G P +K +EA G E R R++ + G NY N
Sbjct: 319 GSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRLLGGSGDNYRN 377
Score = 41.6 bits (96), Expect = 0.007
Identities = 83/318 (26%), Positives = 114/318 (35%), Gaps = 72/318 (22%)
Query: 223 QGLPGANGSSVSQVSG-GSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQ 281
QG A G+ V QV G G+A+ + N V A GN+ + D + A +
Sbjct: 73 QGTREAVGTGVRQVPGFGAADALGNRV---GEAAHALGNTGHEIGRQAEDVIRHGADAVR 129
Query: 282 NGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNG 341
GS V G G AW++ G GI G G G GN G G P V+G
Sbjct: 130 -GSWQGVP--GHNG-AWETS--GGHGIFGSQGGLGGQGQGN--PGGLGTP------WVHG 175
Query: 342 EWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAK---AASSGTTASEG 398
G N GS G NP P G+ N + G A G
Sbjct: 176 YPG-----------NSAGSFG--------MNPQGAPWGQGGNGGPPNFGTNTQGAVAQPG 216
Query: 399 -SSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQN 457
S + N NEG T +G G SN+G G +
Sbjct: 217 YGSVRASNQNEGCTNPPPSGSGGGS----------------------SNSGGGSGSQSGS 254
Query: 458 TAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAV 517
+ S N+NG+ + G ++ S+SGG + GS S+ S S + ++
Sbjct: 255 SG------SGSNGDNNNGSSSGG--SSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSW 306
Query: 518 PANTGWGDSNNKAPSGPG 535
++TG S N SG G
Sbjct: 307 GSSTG-SSSGNHGGSGGG 323
Score = 38.9 bits (89), Expect = 0.044
Identities = 33/131 (25%), Positives = 52/131 (39%), Gaps = 14/131 (10%)
Query: 793 LGPVSSGWGE-----MPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAE 847
+ P + WG+ PN + T+ + +P S N PP SGSG G +
Sbjct: 186 MNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSG 245
Query: 848 PPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLST--SQWEDEEGDVWNNAASQE 905
G +G+ +S ++ G SGG S+ S G N+ S+
Sbjct: 246 -----GGSGSQSGSSG--SGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRG 298
Query: 906 STSSCSSWGNA 916
+ S SSWG++
Sbjct: 299 DSGSESSWGSS 309
>gi|33504489 dermokine isoform 2 precursor [Homo sapiens]
Length = 476
Score = 59.7 bits (143), Expect = 2e-08
Identities = 59/195 (30%), Positives = 80/195 (41%), Gaps = 11/195 (5%)
Query: 223 QGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNS-GFSQGNGDTVNSALSAKQ 281
QG+PG NG+ + SGG GI S GL G GN G +G NSA S
Sbjct: 133 QGVPGHNGAW--ETSGG--HGIFGSQGGL--GGQGQGNPGGLGTPWVHGYPGNSAGSFGM 186
Query: 282 NGSSSAVQKEGSGG----NAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSN 337
N + + G+GG G A PG + + N G N G S ++
Sbjct: 187 NPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGG 246
Query: 338 GVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASE 397
G + G + + + NG S G S S + + GG NS SG+ +S
Sbjct: 247 GSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSW 306
Query: 398 GSSDGSGNHNEGSTG 412
GSS GS + N G +G
Sbjct: 307 GSSTGSSSGNHGGSG 321
Score = 52.8 bits (125), Expect = 3e-06
Identities = 91/390 (23%), Positives = 122/390 (31%), Gaps = 79/390 (20%)
Query: 2 ATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGA-NSNGSAARVWGVATGSSS 60
+TG+ G GH G AL + AGGA S S A G +
Sbjct: 30 STGTNIGEALGH--------GLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGT 81
Query: 61 GLAHCSVSGGDGKMDTMIGDGRSQ--NCWGASNSNAGINLNLNPNANPAAWP-VLGHEGT 117
G+ G + +G+ N A + +A +W V GH G
Sbjct: 82 GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGA 141
Query: 118 VATGNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQ 177
T I +G G GNP G W + P S SF PQ
Sbjct: 142 WETSGGHGIFGSQGGLG---GQGQGNPGGLGTPWVHGYPGNSAG---------SFGMNPQ 189
Query: 178 NLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVS 237
N P N N GA+ P + +N +
Sbjct: 190 GAPWGQGGNGGPPNFGTNT-----------------QGAVAQPGYGSVRASNQN------ 226
Query: 238 GGSAEGISNSVWGLSPGNPATGNSNSGFSQG--NGDTVNSALSAKQNGSSSAVQKEGSGG 295
EG +N P G+SNSG G +G + + + NGSSS GS
Sbjct: 227 ----EGCTNP----PPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSS 278
Query: 296 NAWDSGPPAGPGILAWGRGSGNNGVGNIHSG---AWGHPSRSTSNGVNGEWG----KPPN 348
G G SGN+G SG +WG + S+S G G KP
Sbjct: 279 GGSSGGSSGG--------SSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGC 330
Query: 349 QHSNSDINGKGSTGWESPSVTSQNPTVQPG 378
+ ++ G G +G QN PG
Sbjct: 331 EKPGNEARGSGESG-------IQNSETSPG 353
Score = 47.8 bits (112), Expect = 9e-05
Identities = 48/201 (23%), Positives = 76/201 (37%), Gaps = 33/201 (16%)
Query: 509 WVNAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKS 568
WV+ P + G AP G G G + + A A+ G+ A+NQ +
Sbjct: 172 WVHGYPGNSAGSFGMNPQG--APWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGC 229
Query: 569 PTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGS 628
+NP S GG ++S G +GS D ++ S
Sbjct: 230 -------------------TNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSG 270
Query: 629 GWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQT 688
G + + SG S G+S + N G + G++ G + +W S G++S
Sbjct: 271 GSSSGSSSGGSSGGSSGGSSGNSGGSRGDS---GSESSWGSST---------GSSSGNHG 318
Query: 689 GTGWIGGPVPVKQKDSSEATG 709
G+G G P +K +EA G
Sbjct: 319 GSGGGNGHKPGCEKPGNEARG 339
Score = 41.6 bits (96), Expect = 0.007
Identities = 83/318 (26%), Positives = 114/318 (35%), Gaps = 72/318 (22%)
Query: 223 QGLPGANGSSVSQVSG-GSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQ 281
QG A G+ V QV G G+A+ + N V A GN+ + D + A +
Sbjct: 73 QGTREAVGTGVRQVPGFGAADALGNRV---GEAAHALGNTGHEIGRQAEDVIRHGADAVR 129
Query: 282 NGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNG 341
GS V G G AW++ G GI G G G GN G G P V+G
Sbjct: 130 -GSWQGVP--GHNG-AWETS--GGHGIFGSQGGLGGQGQGN--PGGLGTP------WVHG 175
Query: 342 EWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAK---AASSGTTASEG 398
G N GS G NP P G+ N + G A G
Sbjct: 176 YPG-----------NSAGSFG--------MNPQGAPWGQGGNGGPPNFGTNTQGAVAQPG 216
Query: 399 -SSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQN 457
S + N NEG T +G G SN+G G +
Sbjct: 217 YGSVRASNQNEGCTNPPPSGSGGGS----------------------SNSGGGSGSQSGS 254
Query: 458 TAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAV 517
+ S N+NG+ + G ++ S+SGG + GS S+ S S + ++
Sbjct: 255 SG------SGSNGDNNNGSSSGG--SSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSW 306
Query: 518 PANTGWGDSNNKAPSGPG 535
++TG S N SG G
Sbjct: 307 GSSTG-SSSGNHGGSGGG 323
Score = 38.9 bits (89), Expect = 0.044
Identities = 33/131 (25%), Positives = 52/131 (39%), Gaps = 14/131 (10%)
Query: 793 LGPVSSGWGE-----MPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAE 847
+ P + WG+ PN + T+ + +P S N PP SGSG G +
Sbjct: 186 MNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSG 245
Query: 848 PPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLST--SQWEDEEGDVWNNAASQE 905
G +G+ +S ++ G SGG S+ S G N+ S+
Sbjct: 246 -----GGSGSQSGSSG--SGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRG 298
Query: 906 STSSCSSWGNA 916
+ S SSWG++
Sbjct: 299 DSGSESSWGSS 309
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 58.9 bits (141), Expect = 4e-08
Identities = 71/289 (24%), Positives = 113/289 (39%), Gaps = 32/289 (11%)
Query: 981 KRGLGVTDHNGMAAKPLGCRPPISKESSVDRPTFLDKDGGLVEEPTPSPFLPSPSLKLPL 1040
++G GV + + KP G PP S + G LV++ +P P + P
Sbjct: 3758 QQGPGVQTNQALGPKPQGLMPPSSHQ------------GLLVQQLSPQPPQGPQGMLGPA 3805
Query: 1041 SHSALPSQALGGIASG-------LGMQNLNSSRQIPSGNLGMFGN---SGAAQARTMQQP 1090
+ L Q G + + + SS Q+ G+ G+ + Q + Q
Sbjct: 3806 QVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQ 3865
Query: 1091 PQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPINPQHMTMLNQ 1150
Q + L+ Q SL + Q P++ AQ + + + Q L Q
Sbjct: 3866 QQGSMAGLSHLQQSLMSHSGQ---PKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQ 3922
Query: 1151 LYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQQHQRQLAQALLVK 1210
QLQ Q+LQ QQQ Q Q+ ++QQ+QQ+ + QQQ QQ Q+Q LL +
Sbjct: 3923 QQQLQ--QQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQ 3980
Query: 1211 Q----PPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSS 1255
P ++L P + F S P G L T ++Q++
Sbjct: 3981 SRTLLSPQQQQQQQVALGPGMPAKPLQHF-SSPGALGPTLLLTGKEQNT 4028
Score = 38.9 bits (89), Expect = 0.044
Identities = 69/289 (23%), Positives = 91/289 (31%), Gaps = 60/289 (20%)
Query: 1204 AQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHP--QTPGLPDLQTKEQQSSPNTFAP 1261
AQ L +P PPPP +L P S PS P + P P Q+ Q SP T P
Sbjct: 2379 AQPPLTPRPQPPPPESCCALPPR-------SLPSDPFSRVPASPQSQSSSQ--SPLTPRP 2429
Query: 1262 YPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLP-QWTHPNSMDNLPSAA---SPLEQNP 1317
P+ S + PS+ QSR P H P A L
Sbjct: 2430 LSAEAFCPSPVTPRFQSPDPYS-RPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTS 2488
Query: 1318 SKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSDSDKISNG 1377
G P L GP G E A P P ++ R+ +
Sbjct: 2489 LGAGGFPAALPAGPAG-----------------ELHAKVPSGQPPNFVRSPGTGAFVGTP 2531
Query: 1378 SSINWP-------PEFHPGVPWKGL---QNIDPENDPDVT-----------------PGS 1410
S + + P P VP GL I+ P T P
Sbjct: 2532 SPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSG 2591
Query: 1411 VPTGPTINTTIQDVNRYLLKSGGSSPPSSQNATLPSSSAWPLSASGYSS 1459
P GP+ +T + L+ PP + + +LP S SG +S
Sbjct: 2592 SPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITS 2640
Score = 37.7 bits (86), Expect = 0.097
Identities = 80/341 (23%), Positives = 112/341 (32%), Gaps = 60/341 (17%)
Query: 1214 PPPPPPHLS-------LHPSAGKSAMDSFPSHP----QTPGLPDL--QTKEQQSSPNTFA 1260
P P PHLS L P + + + P P Q G P L Q +E SP T
Sbjct: 754 PRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEG-PHLSPQPEELHLSPQTEE 812
Query: 1261 PYPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKH 1320
P+ L+ + ++ LS + S P+ +H + P + E+ P +
Sbjct: 813 PH-LSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEP 871
Query: 1321 GAIPGGLSIG---PPGKSSIDDSYGRYDLIQNSESPASP-PVAVPHSWSRAKSDSDKISN 1376
G P + PPG+ S+ G L + E P SP P +P S S S S ++
Sbjct: 872 GQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMP 931
Query: 1377 GSSINWPPEFHPGVPWKGLQNIDPEND--------PDVTPGSVPTGPTINTTIQDVNRYL 1428
+ PP P + + P + D P S P + T I
Sbjct: 932 PDPL--PPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPI------- 982
Query: 1429 LKSGGSSPPSSQNATLPSSSAWPLSASGYSSSFSSIASAPSVAGKLSDIKSTWSSGPTSH 1488
SPP N T P + PS +
Sbjct: 983 ------SPPPEANCTDP-------------EPVPPMILPPSPGSPVGPASPILMEPLPPQ 1023
Query: 1489 TQASLSHELWKVPRNSTAPTRPPPGLTNPKPSSTWGASPLG 1529
L H L VP+NS PP L PS SP+G
Sbjct: 1024 CSPLLQHSL--VPQNSPPSQCSPPALPLSVPSP---LSPIG 1059
Score = 37.4 bits (85), Expect = 0.13
Identities = 38/117 (32%), Positives = 48/117 (41%), Gaps = 14/117 (11%)
Query: 1148 LNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQQHQRQLAQAL 1207
L Q QLQL QR+Q+ Q++ Q Q+ +QQ+Q + + QQQ Q Q QAL
Sbjct: 3715 LLQERQLQLQQQRMQLAQKLQQQQQQ-----QQQQQHLLGQVAIQQQQQQGPGVQTNQAL 3769
Query: 1208 LVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTP-GL--PDLQTKEQQSSPNTFAP 1261
K PP H G P PQ P G+ P QQ P P
Sbjct: 3770 GPKPQGLMPPSSH------QGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGP 3820
Score = 35.4 bits (80), Expect = 0.48
Identities = 80/378 (21%), Positives = 122/378 (32%), Gaps = 68/378 (17%)
Query: 987 TDHNGMAAKPLGCRPPISKESSVDRPTFLDKDGGLVEEPTPSPFLPSPSLKLPLSHSALP 1046
T MA +P +P +S +S + L+ +P P P S L+ PL LP
Sbjct: 4053 TTPESMATEPGEVKPSLSGDSQL-----------LLVQPQPQPQPSSLQLQPPLR---LP 4098
Query: 1047 SQALGGIASGLGMQNLNSSRQIPSGNLGMFGNSGAAQARTM------------QQPPQPP 1094
Q Q ++ G+ G G+ +++A ++ QP
Sbjct: 4099 GQQ---------QQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMT 4149
Query: 1095 VQPLNSSQPSLRAQVPQFLSPQVQ--AQLLQFAA--KNIGLNPALLTSPINPQHMTMLNQ 1150
L QP L + PQ +LQ +G+ P + Q + N
Sbjct: 4150 QNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNP 4209
Query: 1151 LYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQ-QVARTITNLQQQIQQHQRQLA----- 1204
+ Q+ Q+Q ++Q Q S ++RQ Q T T+ Q + Q QL
Sbjct: 4210 QLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGP 4269
Query: 1205 ---QALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFAP 1261
+ P P PP L P A + P HP P + K P+ +
Sbjct: 4270 QTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQ 4329
Query: 1262 YPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQ------------WTHPNSMDNLPSA 1309
P P + + G P + Q W P DNL
Sbjct: 4330 LPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPP---DNLAET 4386
Query: 1310 ASPLEQNPSKHGAIPGGL 1327
Q P + +PG L
Sbjct: 4387 -----QKPEQSSLVPGHL 4399
Score = 32.3 bits (72), Expect = 4.1
Identities = 52/250 (20%), Positives = 97/250 (38%), Gaps = 26/250 (10%)
Query: 992 MAAKPLGCRPP--------ISKESSVDRPTFLDKD-GGLVEEPTPSPFLPSPSLKLPLSH 1042
++ KP+G PP ++ + + F D D E P + + L
Sbjct: 3377 LSQKPMGTMPPSMCMKPQQLAMQQQLANSFFPDTDLDKFAAEDIIDPIAKAKMVALKGIK 3436
Query: 1043 SALPSQALGGIASGLGMQNLNSSRQI----PSGNLGMFGNSGAAQARTMQQPPQPPVQPL 1098
+ ++G +A G+ Q ++ Q PS +L +G+ Q R+ P QP P
Sbjct: 3437 KVMAQGSIG-VAPGMNRQQVSLLAQRLSGGPSSDLQNHVAAGSGQERSAGDPSQPRPNPP 3495
Query: 1099 NSSQPSL----RAQVPQFL--SPQVQAQLLQFAAKNIGLNPALLTSPINPQHMTMLNQLY 1152
+Q + + Q ++L + Q+ L+ + IG++ + Q
Sbjct: 3496 TFAQGVINEADQRQYEEWLFHTQQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGRE 3555
Query: 1153 QLQLAYQRLQI---QQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQQHQRQLAQ---A 1206
+ ++L++ QQ +Q Q + +++ + N QQQ QQ Q+Q Q A
Sbjct: 3556 FPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSA 3615
Query: 1207 LLVKQPPPPP 1216
+L P P
Sbjct: 3616 VLALSPSQSP 3625
>gi|239757861 PREDICTED: similar to armadillo repeat containing,
X-linked 4 [Homo sapiens]
Length = 2382
Score = 56.2 bits (134), Expect = 3e-07
Identities = 187/858 (21%), Positives = 300/858 (34%), Gaps = 144/858 (16%)
Query: 149 GAWGNLLPQESTEPQTSTSQNVSFSAQPQNL-NTDG---PNNTNPMNSSPNPINAMQTNG 204
GA + +T P + + SA+PQ + N+ G P N + ++ N ++ + G
Sbjct: 815 GAKNKIRGNPTTVPNSGVGPYTTDSARPQAVANSQGEVLPGAKNKVKANLNAVSKAEA-G 873
Query: 205 LPNWGMAVGMGAIIPPHLQGLPGA------NGSSVSQVSGG-------SAEGISNSVWGL 251
+ G +V A+ H + LPGA N ++VS+ G + ++NS +
Sbjct: 874 MGATG-SVQPQAVANSHCETLPGAKNKVRGNWNAVSKAGAGMDTRGSAQPQAVANSQGEV 932
Query: 252 SPG--NPATGNSNSGFSQG-NGDTVNSA----LSAKQN-----------GSSSAVQKEGS 293
PG N GN N G DTV S L++ Q G+S+ V K G+
Sbjct: 933 LPGAKNKVKGNPNVVSKAGAREDTVGSTQPQVLASSQRETLPGARNKVKGNSNVVSKAGA 992
Query: 294 GGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNS 353
+ S A P ++A + G N G S++ + G G Q S
Sbjct: 993 REDTMGS---AQPQVVANSQRETLPGARNKVKGNSNAISKAEAGA--GIMGSVQVQVVAS 1047
Query: 354 DINGKGSTGWESPSVTSQN--PTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGST 411
G+ G ++ + N P + G + + S A+ + + SE + G+ N +G+T
Sbjct: 1048 -FQGEVLPGAKNKVRGNSNAVPKAEAGADTVGS-AQPQAVANSQSE-TLLGARNKVKGNT 1104
Query: 412 ---GREGTGEGRRRDKG--IIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESP 466
+ GTG G R I+ + D + ++ + E E P
Sbjct: 1105 IAVPKAGTGAGTRHSAQPQIVAGSQGETLPGARDKSMSTSEAEATAEDEAYAKPEAEAMP 1164
Query: 467 RSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDS 526
SE + +GT+A C TQ + +G V W+ A W
Sbjct: 1165 TSESEGGSGTQA--CRKTQPNIHDYYWNGI--------GVEDWIAAER--------WIKF 1206
Query: 527 NNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKS-QHWGDG 585
+ G W +S+S A+ S WSGA+++ +W S + W
Sbjct: 1207 RFQTMDGD--WENSVSWADDENEASIGS---WSGASDKAGIIRSWAVACDETSVKSWAGA 1261
Query: 586 QRSNPA----WS-----AGGGDWADSSSVLGHLGDGKKNGSGW-DADSNRSGSGW----- 630
+ N W+ A GG WA + G K +G W A++ SG W
Sbjct: 1262 RAENVVGIGTWARAGEQASGGLWAGGQTSEGTWAGDKASGGAWTGAENQASGGSWALAGN 1321
Query: 631 ---NDTTRSGNSGWGNSTNTKANPGTNW-GETLKPGPQQNWASKPQDNNVSNWGGAASVK 686
+ +G + G+ +A+ G +W GE G +W + +W GA +
Sbjct: 1322 QAIGELWAAGQASDGSWPGGQAS-GVSWVGEEAIGG---SWTGAENQASEGSWAGAGAGN 1377
Query: 687 QTGTGWIGGPVPVKQKDSSEATGWEEPSPPS-IRRKMEIDDGTSAWGDPSNYNNKTVNMW 745
+ + G V D + W S S K +D S G + + +
Sbjct: 1378 MSSVSYWAGVV-----DQAGGGSWAGTSDQSGGGSKPRFEDQASGEGSWAGAGGQ-ASGG 1431
Query: 746 DRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPVSSGWGEMPN 805
P QSS + T + + V+ L++ SG G P
Sbjct: 1432 SMLGPEDQSSGRSWADTADQASGGSRLGHVDQSSGGAWAGTLDQ--------SGGGSKPR 1483
Query: 806 VHSKT--ENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAF----------- 852
++T E SW + G+ + SSG W + + F
Sbjct: 1484 FENQTTEEGSWAGAGGQA---GGGSKVGPEDQSSGRSWANSGDQISGGFLVGIVDQANGG 1540
Query: 853 GRAGAPVAASALCKPASKSMQEGWGSGGD--EMNLSTSQW---EDEEGDVWNNAASQEST 907
GA AS KP + G GS D E + S+ + GD W Q S
Sbjct: 1541 SWTGAGHPASVGPKPIFEDQVSGRGSWADAREQVVGDSRLGLRDQSSGDSWAGTGDQASG 1600
Query: 908 SSC---------SSWGNA 916
C SWG A
Sbjct: 1601 WFCVCPGSQTNGGSWGGA 1618
Score = 56.2 bits (134), Expect = 3e-07
Identities = 141/670 (21%), Positives = 224/670 (33%), Gaps = 113/670 (16%)
Query: 33 NQSALGA-GGANSNGSAARVWGVATGSSS-------------GLAHCSVSGGDGKMDTMI 78
N++++G+ GA+ R W VA +S G+ + +G
Sbjct: 1226 NEASIGSWSGASDKAGIIRSWAVACDETSVKSWAGARAENVVGIGTWARAGEQASGGLWA 1285
Query: 79 GDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHE--------GTVATGN-PSSICSP 129
G S+ W ++ G A+ +W + G++ G + G+ P S
Sbjct: 1286 GGQTSEGTWAGDKASGGAWTGAENQASGGSWALAGNQAIGELWAAGQASDGSWPGGQASG 1345
Query: 130 VSAIGQNM--GNQNGNPT-GTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLNTDGPNN 186
VS +G+ G+ G + G+W +S S Q + G ++
Sbjct: 1346 VSWVGEEAIGGSWTGAENQASEGSWAGA----GAGNMSSVSYWAGVVDQAGGGSWAGTSD 1401
Query: 187 TNPMNSSPNPINAMQTNGLPNWGMAVGM---GAIIPPHLQGLPGANGSSVSQVSGGSAEG 243
+ S P + Q +G +W A G G+++ P Q + + Q SGGS G
Sbjct: 1402 QSGGGSKPRFED--QASGEGSWAGAGGQASGGSMLGPEDQSSGRSWADTADQASGGSRLG 1459
Query: 244 -ISNSVWGLSPG--NPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEG-SGGNAW- 298
+ S G G + + G S F + + A + Q G S V E S G +W
Sbjct: 1460 HVDQSSGGAWAGTLDQSGGGSKPRFENQTTEEGSWAGAGGQAGGGSKVGPEDQSSGRSWA 1519
Query: 299 DSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGK 358
+SG G L G + G +GA GHP+ P ++G+
Sbjct: 1520 NSGDQISGGFLV---GIVDQANGGSWTGA-GHPA-----------SVGPKPIFEDQVSGR 1564
Query: 359 GSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGSTGREGTGE 418
GS V + +SWA +G AS G+ G + +G+
Sbjct: 1565 GSWADAREQVVGDSRLGLRDQSSGDSWA---GTGDQASGWFCVCPGSQTNGGSWGGASGQ 1621
Query: 419 GRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEA 478
D G G P Q++A ++ SP S+ T A
Sbjct: 1622 ---------DVG-----------------GSRPGPTNQSSAGSWD-SPGSQVSGSCWTGA 1654
Query: 479 WGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWG 538
+ G D +I W P A G + SG G WG
Sbjct: 1655 GAVDQAGGCSKPGFEDQAIGGGF-------W---PGAGDQTGGGSRPGSEDQSSGIGSWG 1704
Query: 539 ---DSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEP---------PKPKSQHWGDGQ 586
+ A A SG +W+G NQ +W P P+ + Q G G
Sbjct: 1705 VAGGQVLGGARPGPADQSSGGSWAGTGNQ-SSGRSWIGPGDQAVDCSKPEFEDQACGGGS 1763
Query: 587 RSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTN 646
+ A G WA S G+ GS ++ +G W + + + S
Sbjct: 1764 WAGAGSQASGESWAGSRP-----GNEAIGGSRMGSEDQATGGSWARSEDQASGRFQVSFE 1818
Query: 647 TKANPGTNWG 656
+AN G +G
Sbjct: 1819 VEANEGFWFG 1828
Score = 50.1 bits (118), Expect = 2e-05
Identities = 107/499 (21%), Positives = 164/499 (32%), Gaps = 90/499 (18%)
Query: 475 GTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGP 534
G EA G + T A N + + + N SSVS W A W +++++ G
Sbjct: 1350 GEEAIGGSWTGAENQASEGSWAGAGAGNMSSVSYWAGVVDQA--GGGSWAGTSDQSGGG- 1406
Query: 535 GVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSA 594
S A+ + +W+GA Q G + + W D
Sbjct: 1407 -------SKPRFEDQASGEG--SWAGAGGQASGGSMLGPEDQSSGRSWAD---------- 1447
Query: 595 GGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSG-----WNDTTRSGNSGWGNSTNTKA 649
D A S LGH+ + +G W ++SG G N TT G+ W A
Sbjct: 1448 -TADQASGGSRLGHV--DQSSGGAWAGTLDQSGGGSKPRFENQTTEEGS--W-------A 1495
Query: 650 NPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASV----KQTGTGWIG-------GPVP 698
G G K GP+ + + N+ G V + G W G GP P
Sbjct: 1496 GAGGQAGGGSKVGPEDQSSGRSWANSGDQISGGFLVGIVDQANGGSWTGAGHPASVGPKP 1555
Query: 699 VKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTT 758
+ + S W + R+ + D D S+ + D+ + +
Sbjct: 1556 IFEDQVSGRGSWAD------AREQVVGDSRLGLRDQSS-GDSWAGTGDQASGWFCVCPGS 1608
Query: 759 NTTTTTTTTTSNTTHRVETP-PPHQAGTQLNRSPLLGPVSSGWGEMPNVHSKTENSWGEP 817
T + S P P +Q+ SP S W + + G
Sbjct: 1609 QTNGGSWGGASGQDVGGSRPGPTNQSSAGSWDSPGSQVSGSCW-----TGAGAVDQAGGC 1663
Query: 818 SSPSTLVDNGTAAWGKPPSSG--SGWGDHPAEPPV-----AFGRAGAPVAASALCKPASK 870
S P ++ G P +G +G G P ++G AG V A PA +
Sbjct: 1664 SKPG--FEDQAIGGGFWPGAGDQTGGGSRPGSEDQSSGIGSWGVAGGQVLGGARPGPADQ 1721
Query: 871 SMQEGW-------------GSGGDEMNLSTSQWEDEE--GDVWNNAASQESTSSCSSWGN 915
S W G G ++ S ++ED+ G W A SQ +S SW
Sbjct: 1722 SSGGSWAGTGNQSSGRSWIGPGDQAVDCSKPEFEDQACGGGSWAGAGSQ---ASGESWAG 1778
Query: 916 APKKGLQKGMKTSGKQDEA 934
+ G G +D+A
Sbjct: 1779 SRPGNEAIGGSRMGSEDQA 1797
Score = 39.3 bits (90), Expect = 0.034
Identities = 127/646 (19%), Positives = 215/646 (33%), Gaps = 112/646 (17%)
Query: 121 GNPSSICSPVSAIGQNMGNQN---GNPTGTL--GAWGNLLPQESTEPQTSTSQNVSFSAQ 175
GNP++ + Q + Q NP G GA + T + + + SAQ
Sbjct: 662 GNPNATSKAGTKADQRVCGQPLVVANPQGEALPGAKNKVKGNPHTVLKVGAGEGTTDSAQ 721
Query: 176 PQNL-NTDGP---NNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGS 231
P+ + + G N + +PN + + VG GA+ LQ + + G
Sbjct: 722 PEAVVSFQGEALLGTKNKVKGNPNVVLKAE----------VGEGAMGTAQLQIMASSKGE 771
Query: 232 SVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKE 291
++ S +G SN+V G TG+ + V K G+ + V
Sbjct: 772 ALLD-SKNKVKGNSNAVSKAGAGTDTTGSVQPQIVANSQGEVLPGAKNKIRGNPTTVPNS 830
Query: 292 GSGGNAWDSGPPAGPGILAWGRG---------------------SGNNGVGNIHSGAWGH 330
G G DS A P +A +G +G G++ A +
Sbjct: 831 GVGPYTTDS---ARPQAVANSQGEVLPGAKNKVKANLNAVSKAEAGMGATGSVQPQAVAN 887
Query: 331 PSRST----SNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWA 386
T N V G W + D G + +V + V PG ++
Sbjct: 888 SHCETLPGAKNKVRGNWNAVSKAGAGMDTRGSA----QPQAVANSQGEVLPGAKNKVKGN 943
Query: 387 KAASSGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKG----IIDQGHIQLPRNDLDPR 442
S A E + + S+ RE R + KG + G + P+
Sbjct: 944 PNVVSKAGAREDTVGSTQPQVLASSQRETLPGARNKVKGNSNVVSKAGAREDTMGSAQPQ 1003
Query: 443 VLSNTG---------------------------WGQTPVKQNTAWEFEESPRSERKNDNG 475
V++N+ G V+ +++ E P ++ K
Sbjct: 1004 VVANSQRETLPGARNKVKGNSNAISKAEAGAGIMGSVQVQVVASFQGEVLPGAKNKVRGN 1063
Query: 476 TEAWGCAATQASNSGGKNDGSIMNSTNTS--SVSGWVNAPPAAVP-ANTGWGDSNNKAPS 532
+ A A A G ++ NS + + V AVP A TG G ++ P
Sbjct: 1064 SNAVPKAEAGADTVGSAQPQAVANSQSETLLGARNKVKGNTIAVPKAGTGAGTRHSAQPQ 1123
Query: 533 -GPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPA 591
G G+++ A KS A ED++ KP+++ +
Sbjct: 1124 IVAGSQGETL------PGARDKSMSTSEAEATAEDEAYA-----KPEAEAMPTSE----- 1167
Query: 592 WSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGW-NDTTRSGNSGWGNSTN---- 646
S GG ++ D NG G + + W ++ + W NS +
Sbjct: 1168 -SEGGSGTQACRKTQPNIHDYYWNGIG--VEDWIAAERWIKFRFQTMDGDWENSVSWADD 1224
Query: 647 -TKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGTG 691
+A+ G+ G + K G ++WA + +V +W GA + G G
Sbjct: 1225 ENEASIGSWSGASDKAGIIRSWAVACDETSVKSWAGARAENVVGIG 1270
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 55.1 bits (131), Expect = 6e-07
Identities = 106/456 (23%), Positives = 167/456 (36%), Gaps = 105/456 (23%)
Query: 951 REPAEEALKSNNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPLGCRPPISKESSVD 1010
R+P+ + L + +A +K D +G + D +GM + P S V
Sbjct: 2159 RKPSSKGLACGSK---EAKDLKARRKKSQDGKGC-LLDSSGMLSPVDSLESPHGYLSDVA 2214
Query: 1011 RPTFLDKDGGLVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPS 1070
P L PSPF SPS+ PL+H LP G + LG+ +LN + +
Sbjct: 2215 SPPLL-----------PSPFQQSPSV--PLNH--LP----GMPDTHLGIGHLNVAAKPEM 2255
Query: 1071 GNLGMFGNSGAAQARTMQQPPQPPVQPL---------NSSQPSLRAQVPQFLSPQVQAQL 1121
LG G + PP+ P+ +SS +L V S Q +
Sbjct: 2256 AALG-----GGGRLAFETGPPRLSHLPVASGTSTVLGSSSGGALNFTVGGSTSLNGQCEW 2310
Query: 1122 LQFAAKNIGLN------------------PALLTSPINPQHMTMLNQLYQLQLAYQ---- 1159
L + N P+L + P H ++ ++YQ
Sbjct: 2311 LSRLQSGMVPNQYNPLRGSVAPGPLSTQAPSLQHGMVGPLHSSLAASALSQMMSYQGLPS 2370
Query: 1160 -RLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQQHQRQLAQALLVKQPPPPPPP 1218
RL Q ++Q Q+ +++ Q+Q NLQ Q Q+ L QPPPPPP
Sbjct: 2371 TRLATQPHLVQTQQVQPQNLQMQQQ-------NLQPANIQQQQSL-------QPPPPPPQ 2416
Query: 1219 PHLSLHPSA----GKSAMDSFPS----HPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPN 1270
PHL + +A G+S + PS P P + T Q SP P + + P
Sbjct: 2417 PHLGVSSAASGHLGRSFLSGEPSQADVQPLGPSSLAVHTILPQESPALPTSLPSSLVPP- 2475
Query: 1271 MNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKHGAIPGGLSIG 1330
+T + PSQ ++ + +DN PS + ++P L+
Sbjct: 2476 -------VTAAQFLTPPSQH-------SYSSPVDNTPSHQLQVPEHPF--------LTPS 2513
Query: 1331 PPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSR 1366
P S ++ SE +SPP ++ +R
Sbjct: 2514 PESPDQWSSSSPHSNVSDWSEGVSSPPTSMQSQIAR 2549
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 54.3 bits (129), Expect = 1e-06
Identities = 182/898 (20%), Positives = 319/898 (35%), Gaps = 130/898 (14%)
Query: 2 ATGSAQGNFTGHTKKTNGNNG---TNGALVQSPSNQSALGAGGANSNGSAARVWGVATGS 58
A+G ++ + T H+ T+ + T ALV+ P++ + S GS A + +
Sbjct: 1933 ASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHS-------SPGSTATTHFPDSST 1985
Query: 59 SSGLAHCSVSGGDGK--MDTMIGDGRSQNC--WGASNSNAGINLNLNPNANPAAW--PVL 112
+SG + S + + T++ RS G S ++ + ++ A P + P L
Sbjct: 1986 TSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGL 2045
Query: 113 GHEGTV---ATGNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNL-LPQESTEPQTSTSQ 168
+ T + +P++ SP S + ++ G+ P +T P S
Sbjct: 2046 SEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHS 2105
Query: 169 NVSFSAQ--------PQNLNTDGPNN-TNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIP 219
S S+ P + T GP+ + +SSP + + G ++ G +
Sbjct: 2106 TTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTT-ALSFGQESTT- 2163
Query: 220 PHLQGLPGANGSSV---SQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSA 276
PG+ +++ S S G E S V S G+P T S + S+
Sbjct: 2164 --FHSSPGSTHTTLFPDSTTSSGIVEA-STRVHS-STGSPRTTLSPA-----------SS 2208
Query: 277 LSAKQNGSSSAVQKEGSGGNAWDSGPPAGPGIL----AWGRGSGNNGVGNIHSGAW--GH 330
S G S+A Q + + S P + + R G+ + + + GH
Sbjct: 2209 TSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGH 2268
Query: 331 PSRST--SNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTS----QNPTVQPGGEHMNS 384
+ST + + P + HS + G+ +T SP T T PG ++
Sbjct: 2269 SEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEAST 2328
Query: 385 --WAKAASSGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPR 442
++ S TT S S G E +T R G P + P
Sbjct: 2329 TFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVS----------PASTTTPG 2378
Query: 443 VL--SNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNS 500
+ S T + +P T F +P + + + T A+ + ++ + +
Sbjct: 2379 LSEESTTVYSSSPGSTETT-VFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLT 2437
Query: 501 TNTSSVSGWVNAPPAAVPAN---TGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHA 557
+++ G + +PA G+ + PS G G ++S +T+
Sbjct: 2438 EESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTP 2497
Query: 558 WSGAANQEDKSPTWGEPPKP----KSQHWGDGQRS-----NPAWSAGGGDWADSSSVLGH 608
+ + + + G P P KS + RS +PA + G +SS+ H
Sbjct: 2498 SRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESST--SH 2555
Query: 609 LGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWA 668
G + + + + G + TT + G ST+T P + T GP Q
Sbjct: 2556 SQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPG---STDTTLLPAS----TTTSGPSQEST 2608
Query: 669 ---SKPQDNNVSNWGG---AASVKQTGTGWIGGPVPVKQK---DSSEATGWEEPSPPSIR 719
S P + + G A S Q T + P DS+ ++G E S
Sbjct: 2609 TSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRV-- 2666
Query: 720 RKMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPP 779
S+ G P T++ +P +Q +TT T +T T+ + T P
Sbjct: 2667 --------HSSTGSPRT----TLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAP 2714
Query: 780 PHQAGTQLNRSPLLGPVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSS 837
++ T +RSP G P H ++ S ST+ + A G PSS
Sbjct: 2715 VEES-TTYHRSP---------GSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSS 2762
Score = 50.8 bits (120), Expect = 1e-05
Identities = 352/1813 (19%), Positives = 592/1813 (32%), Gaps = 259/1813 (14%)
Query: 3 TGSAQGNFTGHTKKTNGNNG---TNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSS 59
+G + + T H+ T+ + T ALV+ P++ + S GS A + ++
Sbjct: 3491 SGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHS-------SPGSTATTHFPDSSTT 3543
Query: 60 SGLAHCSVSGGDGK--MDTMIGDGRSQNC--WGASNSNAGINLNLNPNANPAAW--PVLG 113
SG + S + + T++ RS G S ++ + ++ A P + P L
Sbjct: 3544 SGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLS 3603
Query: 114 HEGTV---ATGNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNL-LPQESTEPQTSTSQN 169
+ T + +P++ SP S + ++ G+ P +T P S
Sbjct: 3604 EKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHST 3663
Query: 170 VSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIP-----PHLQG 224
S S+ T P +T SS + ++G + ++ G +
Sbjct: 3664 TSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHS 3723
Query: 225 LPGANGSSV---SQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQ 281
PG+ +++ S S G E S V S G+P T S + S+ S
Sbjct: 3724 SPGSTHTTLFPDSTTSSGIVEA-STRVHS-STGSPRTTLSPA-----------SSTSPGL 3770
Query: 282 NGSSSAVQKEGSGGNAWDSGPPAGPGIL----AWGRGSGNNGVGNIHSGAW--GHPSRST 335
G S+A Q + + S P + + R G+ + + + GH +ST
Sbjct: 3771 QGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKST 3830
Query: 336 --SNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTS----QNPTVQPGGEHMNS--WAK 387
+ + P + HS + G+ +T SP T T PG ++ ++
Sbjct: 3831 IFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSS 3890
Query: 388 AASSGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNT 447
S TT S S G E +T R G + P + + ++
Sbjct: 3891 PRSPTTTLSPASMTSLGVGEESTTSRSQPGSTH----STVSPASTTTPGLSEESTTVYSS 3946
Query: 448 GWGQTPV----KQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNT 503
G T + T E P + T T+ S + G + S +
Sbjct: 3947 SPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHT--TLFTEDSTTSGLTEES--TAFPG 4002
Query: 504 SSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAAN 563
S S P A+ G + + PS G G +S +T+ + +
Sbjct: 4003 SPASTQTGLPATLTTADLG--EESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPS 4060
Query: 564 QEDKSPTWGEPPKP----KSQHWGDGQRS-----NPAWSAGGGDWADSSSVLGHLGDGKK 614
+ + G P P KS + RS +PA + G +SS+ H G
Sbjct: 4061 STETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESST--SHSQPGST 4118
Query: 615 NGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETL---------KPGPQQ 665
+ + + + SG TT + G ST +PG+ +L PG +
Sbjct: 4119 HTTAFPDSTTTSGLSQEPTTSHSSQG---STEATLSPGSTTASSLGQQSTTFHSSPGDTE 4175
Query: 666 NWASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEID 725
P D S A++ + TG + + SS +TG +E S
Sbjct: 4176 T-TLLPDDTITSGLVEASTPTHSSTGSLHTTLTPA---SSTSTGLQEEST---------- 4221
Query: 726 DGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPH--QA 783
T W ++ S +T +TT ++ TP H +
Sbjct: 4222 ---------------TFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPS-STPTTHFSAS 4265
Query: 784 GTQLNRSPLLGPVSSGWGEMPNV----HSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGS 839
T L RS V S G S T GEP++ + +G+ P S +
Sbjct: 4266 STTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSP--ISSGSTETTALPGSTT 4323
Query: 840 GWGDHPAEPPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWN 899
G +E F +P + PAS + S G +TS G +
Sbjct: 4324 TAG--LSEKSTTF--YSSPRSPDTTLSPASTT------SSGVSEESTTSH--SRPGSMHT 4371
Query: 900 NA---------ASQESTSSCSSWGNAPKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFP 950
A SQEST+S SS G+ L G T+ S L + T
Sbjct: 4372 TAFPSSTTMPGVSQESTASHSSPGSTDTT-LSPGSTTA---------SSLGPESTTFHSS 4421
Query: 951 REPAEEALKSNNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPLGCRPPISKESSVD 1010
E L +N S LLE V H+ + P S +
Sbjct: 4422 PGSTETTLLPDNTTA----SGLLEASTPV---------HSSTGSPHTTLSPAGSTTRQGE 4468
Query: 1011 RPTFLDKDGGLVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPS 1070
TF ++ TP+P P + SA L + G + S
Sbjct: 4469 STTFQSWPNS--KDTTPAP---------PTTTSAFVE--LSTTSHGSPSSTPTTHFSASS 4515
Query: 1071 GNLGMFGNSGAAQARTMQQPPQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNI- 1129
LG S + + P P S+ L + + S Q + F N
Sbjct: 4516 TTLGRSEESTTVHSSPVATATTP--SPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTT 4573
Query: 1130 -GLNPALLTSPINPQHM-----TMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQ 1183
G TS + H + + L + +Y + + S R +E
Sbjct: 4574 SGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEES 4633
Query: 1184 QVARTITNLQQQIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPG 1243
+ + + I R LL + P S+G + P TPG
Sbjct: 4634 TASHSSQDATGTIVLPARSTTSVLLGESTTSPI---------SSGSMETTALPGSTTTPG 4684
Query: 1244 LPDLQTKEQQSSPNTFAPYPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSM 1303
L + T S +T P + ++ T G S + + S + T P+
Sbjct: 4685 LSEKSTTFHSSPSST----------PTTHFSASSTTLGRSEESTTVHSSPVATATTPSPA 4734
Query: 1304 DNLPSAASPLEQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHS 1363
S S L + + + + PG +SS + GR + + S S + ++ P S
Sbjct: 4735 R---STTSGLVEESTAYHSSPGSTQTMHFPESST--ASGRSEESRTSHSSTTHTISSPPS 4789
Query: 1364 WSRAKSDSDKISNGSSINWPPEFHPG---VPWKGLQNIDPENDPD---VTPGSVPTGPTI 1417
+ A + + S + P + ++ + PD +TP +P T
Sbjct: 4790 TTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITP--LPAHFTT 4847
Query: 1418 NTTIQDVNRYLLKSGGSSPPSSQNATLPSSSAWPLSASGYSSSFSSIASAPSVAGKLSDI 1477
+ I + + + P S TL S++ P ++ + +SS S S
Sbjct: 4848 SGRIAESTTFYIS------PGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMT 4901
Query: 1478 KSTWSSGPTS-HTQASLSHELWKVPRNSTAPTRPPPGLTNPKPSSTWGASPLGWTSSYSS 1536
S+ S PTS ++QA +H +T+ + KP ST G ++ S
Sbjct: 4902 SSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSF 4961
Query: 1537 GSAWSTDTSGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKE 1596
++T S S+ + + + G + + P T + N + +S +
Sbjct: 4962 AQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQS 5021
Query: 1597 EAAKAQKSLHMCVLGNTTILAEFAGEEEVNRFLAQGQALPPTSSWQSSSASSQPRLSAAG 1656
VL T + E T+ SS A+ L A
Sbjct: 5022 TPFPDSPGFTHTVLPATLTTTDIGQES--------------TAFHSSSDATGTTPLPARS 5067
Query: 1657 SSHGLVRSDAGHWNAP-----CLGGKGSSELLWGGVPQYSSSLWGPPSADDSRVIGSPTP 1711
++ LV + +P L SS G+ + S++ PS + I S
Sbjct: 5068 TASDLVGEPTTFYISPSPTYTTLFPASSST---SGLTEESTTFHTSPSF--TSTIVSTES 5122
Query: 1712 LTTLLPGDLLSGE 1724
L TL PG G+
Sbjct: 5123 LETLAPGLCQEGQ 5135
Score = 44.7 bits (104), Expect = 8e-04
Identities = 117/567 (20%), Positives = 196/567 (34%), Gaps = 103/567 (18%)
Query: 331 PSRSTSNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTS---QNPTVQPGGEHMNSWAK 387
P+ +TS+GV+ E + S+S +T + + TS Q PT S +
Sbjct: 3013 PATTTSSGVSEE-----SSTSHSQPGSTHTTAFPDSTTTSGLSQEPTA--------SHSS 3059
Query: 388 AASSGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNT 447
S+ T S GS+ S + +T G+ + ++ I + S+T
Sbjct: 3060 QGSTEATLSPGSTTASSLGQQSTTFHSSPGD---TETTLLPDDTITSGLVEASTPTHSST 3116
Query: 448 G---WGQTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSI-MNSTNT 503
G TP +A EES + +W ++ + G + +++T
Sbjct: 3117 GSLHTTLTPASSTSAGLQEESTTFQ--------SWPSSSDTTPSPPGTTAAPVEVSTTYH 3168
Query: 504 SSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDSI----SSTAV----STAAAAKSG 555
S S +A G + + S PG G ++ S+T+V T + SG
Sbjct: 3169 SRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSG 3228
Query: 556 HAWSGA-------ANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGH 608
+ A A +KS T+ P+ +PA + G S H
Sbjct: 3229 STETTALPGSTTTAGLSEKSTTFYSSPRSPDT------TLSPASTTSSG--VSEESTTSH 3280
Query: 609 LGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLKP------- 661
G + + + + G T + G ST+T +PG+ +L P
Sbjct: 3281 SRPGSTHTTAFPGSTTMPGVSQESTASHSSPG---STDTTLSPGSTTASSLGPESTTFHS 3337
Query: 662 GPQQNWASKPQDNNVSNWGGAASV---KQTG---TGWIGGPVPVKQKDSSEATGWEE--- 712
GP + DN ++ AS TG T +Q +S+ W
Sbjct: 3338 GPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKD 3397
Query: 713 --PSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSN 770
P+PP+ ++ T++ G PS+ + SSTT + +TT S+
Sbjct: 3398 TTPAPPTTTSAF-VELSTTSHGSPSSTPTTHFSA---------SSTTLGRSEESTTVHSS 3447
Query: 771 TTHRVETPPPHQA-----------------GTQLNRSPLLGPVSSGWGEMPNVHSKTENS 813
TP P ++ TQ P S E HS T ++
Sbjct: 3448 PVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHT 3507
Query: 814 WGE-PSSPSTLVDNGTAAWGKPPSSGS 839
PS+ S LV+ T+ P S+ +
Sbjct: 3508 ISSAPSTTSALVEEPTSYHSSPGSTAT 3534
Score = 42.4 bits (98), Expect = 0.004
Identities = 114/567 (20%), Positives = 196/567 (34%), Gaps = 103/567 (18%)
Query: 331 PSRSTSNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTS---QNPTVQPGGEHMNSWAK 387
P+ +TS+GV+ E + S+S +T + + TS Q PT S +
Sbjct: 1456 PATTTSSGVSEE-----SSTSHSQPGSTHTTAFPDSTTTSDLSQEPTT--------SHSS 1502
Query: 388 AASSGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNT 447
S+ T S GS+ S + +T G+ + ++ I + S+T
Sbjct: 1503 QGSTEATLSPGSTTASSLGQQSTTFHSSPGD---TETTLLPDDTITSGLVEASTPTHSST 1559
Query: 448 G---WGQTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSI-MNSTNT 503
G TP +A EES + +W ++ + G + +++T
Sbjct: 1560 GSLHTTLTPASSTSAGLQEESTTFQ--------SWPSSSDTTPSPPGTTAAPVEVSTTYH 1611
Query: 504 SSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDSI----SSTAV----STAAAAKSG 555
S S +A G + + S PG G ++ S+T+V T + SG
Sbjct: 1612 SRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSG 1671
Query: 556 HAWSGA-------ANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGH 608
+ A A +KS T+ P+ +PA + G S H
Sbjct: 1672 STETTALPGSTTTAGLSEKSTTFYSSPRSPDT------TLSPASTTSSG--VSEESTTSH 1723
Query: 609 LGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWA 668
G + + + + G T + G ST+T +PG+ +L P +
Sbjct: 1724 SRPGSTHTTAFPGSTTMPGVSQESTASHSSPG---STDTTLSPGSTTASSLGPESTTFHS 1780
Query: 669 SK--------PQDNNVSNWGGAASVKQTGTGWIGGPVP-----VKQKDSSEATGWEE--- 712
S P + S A++ + TG + +Q +S+ W
Sbjct: 1781 SPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKD 1840
Query: 713 --PSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSN 770
P+PP+ ++ T++ G PS+ + SSTT + +TT S+
Sbjct: 1841 TMPAPPTTTSAF-VELSTTSHGSPSSTPTTHFSA---------SSTTLGRSEESTTVHSS 1890
Query: 771 TTHRVETPPPHQA-----------------GTQLNRSPLLGPVSSGWGEMPNVHSKTENS 813
TP P ++ TQ P S E HS T ++
Sbjct: 1891 PVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHT 1950
Query: 814 WGE-PSSPSTLVDNGTAAWGKPPSSGS 839
PS+ S LV+ T+ P S+ +
Sbjct: 1951 ISSPPSTTSALVEEPTSYHSSPGSTAT 1977
Score = 41.2 bits (95), Expect = 0.009
Identities = 85/364 (23%), Positives = 138/364 (37%), Gaps = 57/364 (15%)
Query: 1226 SAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPNMNVNSMDMTGGLSVK 1285
S+G + P PGL + T TF P + P+ MT +
Sbjct: 614 SSGSMETTALPGSTTKPGLSEKST--------TFYSSPRS---PDTTHLPASMTSSGVSE 662
Query: 1286 DPSQSQSRLPQWTHPNSMDN---LP-----SAASPLEQNPSKHGAIPGGL---SIGP--- 1331
+ + S SR P TH + +P S AS P+ PG S+GP
Sbjct: 663 ESTTSHSR-PGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYT 721
Query: 1332 -----PGKSS---IDDSYGRYDLIQNSESPASPPVAVPHSW-SRAKSDSDKISNGSSINW 1382
PG + + D+ L++ S P PH+ S A S + + + + +W
Sbjct: 722 TFHSRPGSTETTLLPDNTTASGLLEAS-MPVHSSTRSPHTTLSPAGSTTRQGESTTFHSW 780
Query: 1383 PP--EFHPGVPWKGLQNIDPENDPDVTPGSVPTG-----PTINTTIQDVNRYLLKSGGSS 1435
P + P P ++P +P S+PT T + +++ Y SS
Sbjct: 781 PSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTY-----HSS 835
Query: 1436 PPSSQNATLPSSSAWP----LSASGYSSSFSSIASAPSVAGKLSDIKSTWSSGP----TS 1487
P S+Q P S S + +SS+ +I+SAPS L + +++ S P T+
Sbjct: 836 PGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATT 895
Query: 1488 HTQASLSHELWKVPRNSTAPTRPPPG-LTNPKPSSTWGASPLGWTSSYSSGSAWSTDTSG 1546
H S + ++ ++ G + P S+T TS SSGS +T G
Sbjct: 896 HFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPG 955
Query: 1547 RTSS 1550
T++
Sbjct: 956 STTT 959
Score = 36.2 bits (82), Expect = 0.28
Identities = 148/751 (19%), Positives = 246/751 (32%), Gaps = 128/751 (17%)
Query: 114 HEGTVATGNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFS 173
H ATG +++ SA +G +P + LP +T S ++ +F
Sbjct: 3196 HSSPGATG--TALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLS-EKSTTFY 3252
Query: 174 AQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGS-S 232
+ P++ +T +P +++ + ++ T G H PG+
Sbjct: 3253 SSPRSPDT----TLSPASTTSSGVSEESTTSHSRPGST---------HTTAFPGSTTMPG 3299
Query: 233 VSQVSGGSAEGISNSVWGLSPGNPAT---GNSNSGFSQGNGDTVNSALSAKQNGSS---S 286
VSQ S S ++ LSPG+ G ++ F G G T + L S +
Sbjct: 3300 VSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEA 3359
Query: 287 AVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRST-----SNGVNG 341
+ S G+ + PAG G + N P+ ++ S +G
Sbjct: 3360 STPVHSSTGSPHTTLSPAG-STTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHG 3418
Query: 342 EWGKPPNQHSNSDINGKG-----STGWESPSVTSQNP-----TVQPGGEHMNSWAKAASS 391
P H ++ G +T SP T+ P T E ++ + S
Sbjct: 3419 SPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGS 3478
Query: 392 GTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQ 451
T SD + E ST + ++ P + +T
Sbjct: 3479 TQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSP--GSTATTH 3536
Query: 452 TPVKQNTAWEFEESPRSERKND-NGTEAWGCAATQASNSGGKNDGSIMN-STNTSSVSGW 509
P T+ EES S D GT +T + G I + S T+++ G
Sbjct: 3537 FPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGS 3596
Query: 510 VNAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSP 569
P + + T + +P P +T +S A+ SG + E+ +
Sbjct: 3597 TTTPGLSEKSTTF-----HSSPRSP--------ATTLSPASTTSSGVS-------EESTT 3636
Query: 570 TWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSG 629
+ P + + D + P S S H G + + A + SGS
Sbjct: 3637 SHSRPGSTHTTAFPDST-TTPGLSR--------HSTTSHSSPGSTDTTLLPASTTTSGSS 3687
Query: 630 WNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTG 689
TT +SG ST+T +PG+ A S Q
Sbjct: 3688 QESTTSHSSSG---STDTALSPGSTT--------------------------ALSFGQES 3718
Query: 690 TGWIGGPVPVKQK---DSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWD 746
T + P DS+ ++G E S S+ G P T++
Sbjct: 3719 TTFHSSPGSTHTTLFPDSTTSSGIVEASTRV----------HSSTGSPRT----TLSPAS 3764
Query: 747 RNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPVSSGWGEMPNV 806
+P +Q +T T +T T+ + T P ++ T +RSP G P
Sbjct: 3765 STSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEES-TTYHRSP---------GSTPTT 3814
Query: 807 HSKTENSWGEPSSPSTLVDNGTAAWGKPPSS 837
H ++ S ST+ + A G PSS
Sbjct: 3815 HFPASSTTSGHSEKSTIFHSSPDASGTTPSS 3845
Score = 34.3 bits (77), Expect = 1.1
Identities = 75/378 (19%), Positives = 131/378 (34%), Gaps = 73/378 (19%)
Query: 453 PVKQNTAWEFEESPR---SERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGW 509
P T+ EES S + T + A S + ++S++SG
Sbjct: 517 PESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGR 576
Query: 510 VNAPPAAVPANTGWGDSNNKAPSGPGVW-GDS----ISSTAVSTAAAAKSGHAWSGAANQ 564
A+ + + A S P V GDS ISS ++ T A S +
Sbjct: 577 SEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGS----TTKPGL 632
Query: 565 EDKSPT-WGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADS 623
+KS T + P P + H PA G S H G + + + +
Sbjct: 633 SEKSTTFYSSPRSPDTTHL-------PASMTSSG--VSEESTTSHSRPGSTHTTAFPGST 683
Query: 624 NRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAA 683
G T + G T+T +PG+ +L P + S+P +
Sbjct: 684 TMPGLSQESTASHSSPG---PTDTTLSPGSTTASSLGP-EYTTFHSRPGSTETT----LL 735
Query: 684 SVKQTGTGWIGGPVPV------------------KQKDSSEATGWEE-----PSPPSIRR 720
T +G + +PV +Q +S+ W P+PP+
Sbjct: 736 PDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTS 795
Query: 721 KMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTT---------------TNTTT--- 762
++ T++ G PS+ ++ + +++ STT ++TT+
Sbjct: 796 AF-VEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRG 854
Query: 763 -TTTTTTSNTTHRVETPP 779
+TT+ S+TTH + + P
Sbjct: 855 EESTTSHSSTTHTISSAP 872
Score = 34.3 bits (77), Expect = 1.1
Identities = 92/394 (23%), Positives = 139/394 (35%), Gaps = 76/394 (19%)
Query: 1224 HPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTF--APYPLAGL--NPNMNVNSMDMT 1279
H S G + FP T G + T S+ +T AP + L P +S T
Sbjct: 833 HSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGST 892
Query: 1280 GGLSVKDPSQSQSRLPQWTHPNSMDN------LP-----------SAASPLEQNPSKHGA 1322
D S + R + T +S + LP S SP+ + A
Sbjct: 893 ATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTA 952
Query: 1323 IPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSDSDKISNGSSINW 1382
+PG S PG S ++ SP SP + S A + S +S S+ +
Sbjct: 953 LPG--STTTPGLSERSTTF--------HSSPRSPATTL----SPASTTSSGVSEESTTS- 997
Query: 1383 PPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLL-KSGGSSPPSSQN 1441
P G + D TPG T +++ + LL S +S PS ++
Sbjct: 998 --RSRP-----GSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQES 1050
Query: 1442 ATLPSSSA--------WPLSASGYSSSFSSIASAPSVAGKLSDIKSTWSSG----PTSHT 1489
T SSS +A + ++ S P ST SSG T
Sbjct: 1051 TTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVH 1110
Query: 1490 QASLSHELWKVPRNSTAP----------TRPPPGLTNPKPSSTWGASPLGWTSSY--SSG 1537
++ S P +ST+P T P T P P ST +P+ +++Y S G
Sbjct: 1111 SSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPST-ATAPVEESTTYHRSPG 1169
Query: 1538 SA------WSTDTSGRTSSWLVLRNLTPQIDGST 1565
S S+ TSG + + + +P G+T
Sbjct: 1170 STPTTHFPASSTTSGHSEKSTIFHS-SPDASGTT 1202
Score = 34.3 bits (77), Expect = 1.1
Identities = 171/866 (19%), Positives = 281/866 (32%), Gaps = 116/866 (13%)
Query: 23 TNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGLAHCSVSGGDGKM--DTMIGD 80
T L Q P+ + G + S + G S H S + + D I
Sbjct: 1488 TTSDLSQEPTTSHS-SQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITS 1546
Query: 81 GRSQNCWGASNSNAGINLNLNPNANPAA-----------WPVLGHEGTVATGNPSSICSP 129
G + +S ++ L P ++ +A WP P + +P
Sbjct: 1547 GLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWP---SSSDTTPSPPGTTAAP 1603
Query: 130 VSAIGQNMGNQNGNPTGTLGAWGNLL--PQESTEPQTS--TSQNVSFSAQPQNLNTDGPN 185
V + PT A L +EST +S + F + G
Sbjct: 1604 VEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEP 1663
Query: 186 NTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQG--LPGANGSSVSQVSGGSAEG 243
T+P++S + +T LP G+ P S S S G +E
Sbjct: 1664 TTSPISSG-----STETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEE 1718
Query: 244 ISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPP 303
+ S PG+ T + G + G + S S GS+ GS +
Sbjct: 1719 STTS--HSRPGSTHT-TAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGS-----TTASS 1770
Query: 304 AGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGSTGW 363
GP + G+ + S V+ G P ++ ++ GST
Sbjct: 1771 LGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSP-----HTTLSPAGSTTR 1825
Query: 364 ESPSVTSQN-PTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGSTGREGTGEGRRR 422
+ S T Q+ P+ + + A +T S GS + + ++ T GR
Sbjct: 1826 QGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASS---TTLGRSE 1882
Query: 423 DKGIIDQGHIQLP------RNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGT 476
+ + + R+ V +T + +P T E S S R ++ T
Sbjct: 1883 ESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRT 1942
Query: 477 EAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVP---ANTGWGDSNNKAPSG 533
++T + S + S + TS S + P +G + + + S
Sbjct: 1943 SH---SSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSS 1999
Query: 534 PGVWGDSI----SSTAV----STAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDG 585
G + S+T+V ST + SG + A +P E KS +
Sbjct: 2000 QDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSE----KSTTFHSS 2055
Query: 586 QRS-----NPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSG 640
RS +PA + G S H G + + + + G + TT + G
Sbjct: 2056 PRSPATTLSPASTTSSG--VSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPG 2113
Query: 641 WGNSTNTKANPGTNWGETLKPGPQQNWA---SKPQDNNVSNWGG---AASVKQTGTGWIG 694
ST+T P + T GP Q S P + + G A S Q T +
Sbjct: 2114 ---STDTTLLPAS----TTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHS 2166
Query: 695 GPVPVKQK---DSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNPV 751
P DS+ ++G E S S+ G P T++ +P
Sbjct: 2167 SPGSTHTTLFPDSTTSSGIVEASTRV----------HSSTGSPRT----TLSPASSTSPG 2212
Query: 752 IQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPVSSGWGEMPNVHSKTE 811
+Q +T T +T T+ + T P ++ T +RSP G P H
Sbjct: 2213 LQGESTAFQTHPASTHTTPSPPSTATAPVEES-TTYHRSP---------GSTPTTHFPAS 2262
Query: 812 NSWGEPSSPSTLVDNGTAAWGKPPSS 837
++ S ST+ + A G PSS
Sbjct: 2263 STTSGHSEKSTIFHSSPDASGTTPSS 2288
Score = 33.5 bits (75), Expect = 1.8
Identities = 77/341 (22%), Positives = 126/341 (36%), Gaps = 43/341 (12%)
Query: 1224 HPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPNMNVNSMDMTGGLS 1283
H G + +FP TPGL T S +T ++ + +
Sbjct: 2555 HSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGST---------------DTTLLPASTT 2599
Query: 1284 VKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKHG--AIPGGLSIGPPGKSSIDDSY 1341
PSQ + T +S + +A SP G + S G + DS
Sbjct: 2600 TSGPSQEST-----TSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDST 2654
Query: 1342 GRYDLIQNSESPASPPVAVPHSWSRAKSDSDKISNGSSI--NWPPEFH--PGVPWKGLQN 1397
+++ S S + + S A S S + S+ P H P P
Sbjct: 2655 TSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAP 2714
Query: 1398 IDPENDPDVTPGSVPTG--PTINTTIQDVNRYLL-----KSGGSSPPSSQNATLPSSSAW 1450
++ +PGS PT P +TT + + + G++P S+ + T +
Sbjct: 2715 VEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGEST 2774
Query: 1451 PLSASGYSSSFSSIASAPSVAGKLSDIKSTWSSGPTSHTQ--ASLSHELWKVPRNSTAPT 1508
S S+ +++ + + G LS+ +T+ S P S T + S V ST +
Sbjct: 2775 TSRISPGSTEITTLPGSTTTPG-LSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTT-S 2832
Query: 1509 RPPPGLT----NPKPSSTWGASPLGWTSSYSSGSAWSTDTS 1545
R PG T +P ++T G S T+ YSS S ST+T+
Sbjct: 2833 RSQPGSTHSTVSPASTTTPGLSEES-TTVYSS-SPGSTETT 2871
Score = 32.7 bits (73), Expect = 3.1
Identities = 68/333 (20%), Positives = 121/333 (36%), Gaps = 42/333 (12%)
Query: 1222 SLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPNMNVNSMDMTGG 1281
++H S +A P+ T GL + T SSP G M+ G
Sbjct: 1886 TVHSSPVATATTPSPARSTTSGLVEESTA-YHSSP---------GSTQTMHFPESSTASG 1935
Query: 1282 LSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKHGAIPGGLSIGPPGKSSIDDSY 1341
S +SR + +++ + PS S L + P+ + + PG + SS
Sbjct: 1936 RS------EESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGR 1989
Query: 1342 GRYDLIQNSESPASPPVAVP----HSWSRAKSDSDKISNGSSINWPPEFHPGVPWKGLQN 1397
+S A+ + +P S +S + IS+GS P ++
Sbjct: 1990 SEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKS 2049
Query: 1398 IDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSGGSSPPSSQNATLPSSSAWPLSASGY 1457
+ P ++ T ++ + + + + S P S+ P S+ P G
Sbjct: 2050 TTFHSSPRSPATTLSPASTTSSGVSEES----TTSHSRPGSTHTTAFPDSTTTP----GL 2101
Query: 1458 SSSFSSIASAPSVAGKLSDIKSTWSSGPTSHTQASLSHELWKVPRNSTAPTRPPPGLTNP 1517
S ++ S+P ST +SGP+ + S S + T PG T
Sbjct: 2102 SRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSP-------GSTDTALSPGSTTA 2154
Query: 1518 ----KPSSTWGASPLGWTSSYSSGSAWSTDTSG 1546
+ S+T+ +SP S++++ ST +SG
Sbjct: 2155 LSFGQESTTFHSSP---GSTHTTLFPDSTTSSG 2184
Score = 32.3 bits (72), Expect = 4.1
Identities = 78/357 (21%), Positives = 120/357 (33%), Gaps = 31/357 (8%)
Query: 1222 SLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSS--------PNTFAPYPLAGLNPNMNV 1273
S H S G +A FP T G + T S P L G + +
Sbjct: 884 SYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPI 943
Query: 1274 NSMDM-TGGL--SVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKHGAI----PGG 1326
+S M T L S P S+ + P S S AS S+ PG
Sbjct: 944 SSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGS 1003
Query: 1327 LSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRA-KSDSDKISNGSSINWPPE 1385
S+ R+ +S ++ +P S + + S S+ SS +
Sbjct: 1004 THTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTA 1063
Query: 1386 FHPGVPWK---GLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSGGS-----SPP 1437
PG G ++ ++P T ++ T ++ I + + + S GS SP
Sbjct: 1064 LSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPA 1123
Query: 1438 SSQNATLPSSSAWPLSASGYSSSFSSIASAPSVAGKLSDIKSTW----SSGPTSHTQASL 1493
SS + L S + + +S + S PS A + +T+ S PT+H AS
Sbjct: 1124 SSTSPGLQGEST---AFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASS 1180
Query: 1494 SHELWKVPRNSTAPTRPPPGLTNPKPSSTWGASPLGWTSSYSSGSAWSTDTSGRTSS 1550
+ + G T ST TS S GS T G T++
Sbjct: 1181 TTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTT 1237
Score = 31.6 bits (70), Expect = 7.0
Identities = 69/342 (20%), Positives = 120/342 (35%), Gaps = 37/342 (10%)
Query: 1224 HPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPNMNVNSMDMTGGLS 1283
H G + +FP PG+ T S +T L+P S S
Sbjct: 3280 HSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTT-----LSPGSTTAS-------S 3327
Query: 1284 VKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKHGAIPGG-LSIGPPGKSSIDDSYG 1342
+ S + P T + + +A+ LE + H + ++ P G ++
Sbjct: 3328 LGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGEST 3387
Query: 1343 RYDLIQNSESPASPPVAVPHSWSRAKSDSDKISNGSSINWPPEFHPGVPWKGLQNIDPEN 1402
+ NS+ P ++ + S S + P H L +
Sbjct: 3388 TFQSWPNSKDTTPAPPTTTSAFVELSTTSH-----GSPSSTPTTHFSASSTTLGRSEEST 3442
Query: 1403 DPDVTPGSVPTGP-----TINTTIQDVNRYLLKSGGSSPPSSQNATLPSSSAWP----LS 1453
+P + T P T + +++ Y SSP S+Q P S S
Sbjct: 3443 TVHSSPVATATTPSPARSTTSGLVEESTTY-----HSSPGSTQTMHFPESDTTSGRGEES 3497
Query: 1454 ASGYSSSFSSIASAPSVAGKLSDIKSTWSSGP----TSHTQASLSHELWKVPRNSTAPTR 1509
+ +SS+ +I+SAPS L + +++ S P T+H S + ++ ++
Sbjct: 3498 TTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQ 3557
Query: 1510 PPPG-LTNPKPSSTWGASPLGWTSSYSSGSAWSTDTSGRTSS 1550
G + P S+T TS SSGS +T G T++
Sbjct: 3558 DATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTT 3599
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 54.3 bits (129), Expect = 1e-06
Identities = 221/1012 (21%), Positives = 329/1012 (32%), Gaps = 190/1012 (18%)
Query: 547 STAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVL 606
+ AAAA+ G AA QE + P G PP+P + DG SN GGG
Sbjct: 40 AAAAAAERGEM-KAAAGQESEGPAVG-PPQPLGKELQDGAESN-----GGG--------- 83
Query: 607 GHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQN 666
G G G G G + D S +GN+G P N T PG
Sbjct: 84 GGGGAGSGGGPGAEPDLKNS---------NGNAG--------PRPALNNNLTEPPGGGGG 126
Query: 667 WASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDD 726
+S + A G G G P ++ A ++ +
Sbjct: 127 GSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQS 186
Query: 727 GTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQ 786
G +P Y N D P Q + S +R PPP A
Sbjct: 187 GGGGGLEP--YAGPQQNSHDHGFPNHQYN-------------SYYPNRSAYPPP--APAY 229
Query: 787 LNRSPLLGPVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPA 846
SP G SG +S SS S+ A G S +G G
Sbjct: 230 ALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGG---T 286
Query: 847 EPPVAFGRAGAPVAASALCKPASKSMQEGWG----SGGDEMNLSTSQWEDEEGDVWNNAA 902
P A P L P+S +G+ SGG + + D W AA
Sbjct: 287 PQPTA-----TPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAA 341
Query: 903 SQESTSSCSSWGNAPKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPREPAEEALKSNN 962
+ + ++ S G A ++ M ++R + P P ++ K
Sbjct: 342 AAAAAAAAS--GGAQQRSHHAPMSPGSSGGGGQPLARTPQ-------PSSPMDQMGK--- 389
Query: 963 MNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPLGCRPPISKESSVDRPTFLDKDGGLV 1022
M +P G P S++ P+ + G
Sbjct: 390 -----------------------------MRPQPYGGTNPYSQQQGP--PSGPQQGHGYP 418
Query: 1023 EEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFGNSGAA 1082
+P S +P + P++ A+GG++ Q +Q PSG +G G
Sbjct: 419 GQPYGSQ---TPQ-RYPMTMQGRAQSAMGGLS--YTQQIPPYGQQGPSG----YGQQGQT 468
Query: 1083 QARTMQQPPQPPVQPLNSSQPSLRA--------QVPQFLSPQVQAQLLQFAAKNIGLNPA 1134
Q P QP S QP + Q PQ PQ+Q+ P
Sbjct: 469 PYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSS-----------QPP 517
Query: 1135 LLTSPINPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQ 1194
P P H Q Q+ Q + S +QQ QQ A + + Q
Sbjct: 518 YSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQA 577
Query: 1195 QIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQS 1254
Q Q Q +Q Q PPP L + S S PS + G + QS
Sbjct: 578 AYPQPQSQQSQQTAYSQQRFPPPQ---ELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQS 634
Query: 1255 SPNTFAPYPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLE 1314
P++ L L+ +++ M G LS P S S + + + A SP
Sbjct: 635 RPSS-----LPDLSGSIDDLPMGTEGALS---PGVSTSGISS----SQGEQSNPAQSPFS 682
Query: 1315 QNPSKHGAIPG--GLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAK---S 1369
+ S H +PG G S P G + + Q+ P S P AVP + +
Sbjct: 683 PHTSPH--LPGIRGPSPSPVGSPA--------SVAQSRSGPLS-PAAVPGNQMPPRPPSG 731
Query: 1370 DSDKI----SNGSSINWPPEF---HPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQ 1422
SD I N SSI + +P +P Q P+ ++P P+G I+T +
Sbjct: 732 QSDSIMHPSMNQSSIAQDRGYMQRNPQMP----QYSSPQPGSALSPRQ-PSGGQIHTGMG 786
Query: 1423 DVNRYLLKS----GGSSPPSSQNATLPSSSAWP---LSASGYSSSFSSIASAPSVAGKLS 1475
+ + S GG P P+ +A P ++G + + + + + G+
Sbjct: 787 SYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQ-P 845
Query: 1476 DIKSTWSSGPTSHTQASLSH-----ELWKVPRNSTAPTRPPPGLTNPKPSST 1522
I + P + AS+ + + +P + PPPG N K T
Sbjct: 846 GIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQET 897
Score = 37.7 bits (86), Expect = 0.097
Identities = 87/393 (22%), Positives = 122/393 (31%), Gaps = 82/393 (20%)
Query: 16 KTNGNNGTNGALVQSPSNQSALGAGGA--------NSNGSAARVWGVATGSSSGLAHCSV 67
++NG G GA G+GG NSNG+A G ++ L
Sbjct: 78 ESNGGGGGGGA-----------GSGGGPGAEPDLKNSNGNA----GPRPALNNNLTEPPG 122
Query: 68 SGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHE-GTVATGNPSSI 126
GG G D + P++ AA P + G +PS++
Sbjct: 123 GGGGGSSD---------------------GVGAPPHSAAAALPPPAYGFGQPYGRSPSAV 161
Query: 127 CSPVSAI-GQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQN-LNTDGP 184
+ +A+ Q G Q L + G EP QN P + N+ P
Sbjct: 162 AAAAAAVFHQQHGGQQSPGLAALQSGGG----GGLEPYAGPQQNSHDHGFPNHQYNSYYP 217
Query: 185 NNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGSAEGI 244
N + +P + G P G A G+ PP ++ SS +Q G+ G
Sbjct: 218 NRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGG 277
Query: 245 SNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDSGP-- 302
S G P T L+ SSA +G G + GP
Sbjct: 278 GPSAAGGGTPQP---------------TATPTLNQLLTSPSSARGYQGYPGGDYSGGPQD 322
Query: 303 ------PAGPGILAWGRGSGNNGVGNIHSGAWGHPSRS-TSNGVNGEWGKP----PNQHS 351
PA WG + GA + S G +G G+P P S
Sbjct: 323 GGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSS 382
Query: 352 NSDINGK---GSTGWESPSVTSQNPTVQPGGEH 381
D GK G +P Q P P H
Sbjct: 383 PMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGH 415
Score = 37.0 bits (84), Expect = 0.17
Identities = 158/777 (20%), Positives = 253/777 (32%), Gaps = 139/777 (17%)
Query: 15 KKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVAT---------GSSSGLAHC 65
K +NGN G AL + + G GG +S+G A A G G +
Sbjct: 101 KNSNGNAGPRPALNNNLTEPPG-GGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPS 159
Query: 66 SVSGGDGKMDTMIGDGRSQNCWGASNSNAGINLN--LNPNANPAAWPVLGHEGTVATGNP 123
+V+ + G+ A S G L P N H+ N
Sbjct: 160 AVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNR 219
Query: 124 SSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQN-LNTD 182
S+ P A + +G A G+ P S+ +S+S SF+ Q +
Sbjct: 220 SAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSS--SFAQQRFGAMGGG 277
Query: 183 GPN---NTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGG 239
GP+ P ++ +N + T+ G QG PG + S Q GG
Sbjct: 278 GPSAAGGGTPQPTATPTLNQLLTSPSSARG------------YQGYPGGDYSGGPQ-DGG 324
Query: 240 SAEG---ISNSVWGLSPGNPATGNSNSGFSQ-------------GNGD----TVNSALSA 279
+ +G +++ WG + A ++ G Q G G T +
Sbjct: 325 AGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPM 384
Query: 280 KQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHP------SR 333
Q G G+ + GPP+GP +G G G +P ++
Sbjct: 385 DQMGKMRPQPYGGTNPYSQQQGPPSGP-----QQGHGYPGQPYGSQTPQRYPMTMQGRAQ 439
Query: 334 STSNGVNGEWGKPP-NQHSNSDINGKGSTGW---ESP-----------SVTSQNPTVQPG 378
S G++ PP Q S +G T + +SP SQ P QP
Sbjct: 440 SAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPS 499
Query: 379 GEHMNSWAKAASSGTTASEGSSDGSGNHNEGST---GREGTGEGRRRDKGIIDQGHIQLP 435
+ + H + ++ T + + + Q Q P
Sbjct: 500 YQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSP 559
Query: 436 RNDLDPR-----VLSNTG---WGQTPVKQNTAWEFEE-SPRSERKNDNGTEAWGCAATQA 486
P+ LS Q+ Q TA+ + P E D+ A +
Sbjct: 560 YQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMT 619
Query: 487 SNSGGKNDGSIMNSTNTSS---VSGWVNAPPAAVPA-----------NTGWGDSNNKA-- 530
S+ GG+ D ++ + SS +SG ++ P ++ G+ +N A
Sbjct: 620 SSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQS 679
Query: 531 -------PSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWG 583
P PG+ G S S + A S AA P PP+P S
Sbjct: 680 PFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAA-----VPGNQMPPRPPS---- 730
Query: 584 DGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSG---NSG 640
GQ + + + SS+ G ++N S + GS + SG ++G
Sbjct: 731 -GQSDSIMHPS-----MNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTG 784
Query: 641 WGN-STNTKANPGTNWGETLKPGPQQNWASKPQDN-----NVSNWGGAASVKQTGTG 691
G+ N+ + G G+ GPQ + +P N N + G A + G G
Sbjct: 785 MGSYQQNSMGSYGPQGGQY---GPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAG 838
Score = 32.0 bits (71), Expect = 5.3
Identities = 28/91 (30%), Positives = 38/91 (41%), Gaps = 17/91 (18%)
Query: 1211 QPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSS---PNTFAPYPLAGL 1267
+PP P PH + P G S +S G+ D S+ N+ P P G
Sbjct: 1161 KPPTPASTPHSQIPPLPGMSRSNSV-------GIQDAFNDGSDSTFQKRNSMTPNP--GY 1211
Query: 1268 NPNMNVNSMDMTGGLSV---KDPSQSQSRLP 1295
P+MN + DM G +S KDP S + P
Sbjct: 1212 QPSMNTS--DMMGRMSYEPNKDPYGSMRKAP 1240
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 54.3 bits (129), Expect = 1e-06
Identities = 221/1012 (21%), Positives = 329/1012 (32%), Gaps = 190/1012 (18%)
Query: 547 STAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVL 606
+ AAAA+ G AA QE + P G PP+P + DG SN GGG
Sbjct: 40 AAAAAAERGEM-KAAAGQESEGPAVG-PPQPLGKELQDGAESN-----GGG--------- 83
Query: 607 GHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQN 666
G G G G G + D S +GN+G P N T PG
Sbjct: 84 GGGGAGSGGGPGAEPDLKNS---------NGNAG--------PRPALNNNLTEPPGGGGG 126
Query: 667 WASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDD 726
+S + A G G G P ++ A ++ +
Sbjct: 127 GSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQS 186
Query: 727 GTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQ 786
G +P Y N D P Q + S +R PPP A
Sbjct: 187 GGGGGLEP--YAGPQQNSHDHGFPNHQYN-------------SYYPNRSAYPPP--APAY 229
Query: 787 LNRSPLLGPVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPA 846
SP G SG +S SS S+ A G S +G G
Sbjct: 230 ALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGG---T 286
Query: 847 EPPVAFGRAGAPVAASALCKPASKSMQEGWG----SGGDEMNLSTSQWEDEEGDVWNNAA 902
P A P L P+S +G+ SGG + + D W AA
Sbjct: 287 PQPTA-----TPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAA 341
Query: 903 SQESTSSCSSWGNAPKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPREPAEEALKSNN 962
+ + ++ S G A ++ M ++R + P P ++ K
Sbjct: 342 AAAAAAAAS--GGAQQRSHHAPMSPGSSGGGGQPLARTPQ-------PSSPMDQMGK--- 389
Query: 963 MNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPLGCRPPISKESSVDRPTFLDKDGGLV 1022
M +P G P S++ P+ + G
Sbjct: 390 -----------------------------MRPQPYGGTNPYSQQQGP--PSGPQQGHGYP 418
Query: 1023 EEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFGNSGAA 1082
+P S +P + P++ A+GG++ Q +Q PSG +G G
Sbjct: 419 GQPYGSQ---TPQ-RYPMTMQGRAQSAMGGLS--YTQQIPPYGQQGPSG----YGQQGQT 468
Query: 1083 QARTMQQPPQPPVQPLNSSQPSLRA--------QVPQFLSPQVQAQLLQFAAKNIGLNPA 1134
Q P QP S QP + Q PQ PQ+Q+ P
Sbjct: 469 PYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSS-----------QPP 517
Query: 1135 LLTSPINPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQ 1194
P P H Q Q+ Q + S +QQ QQ A + + Q
Sbjct: 518 YSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQA 577
Query: 1195 QIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQS 1254
Q Q Q +Q Q PPP L + S S PS + G + QS
Sbjct: 578 AYPQPQSQQSQQTAYSQQRFPPPQ---ELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQS 634
Query: 1255 SPNTFAPYPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLE 1314
P++ L L+ +++ M G LS P S S + + + A SP
Sbjct: 635 RPSS-----LPDLSGSIDDLPMGTEGALS---PGVSTSGISS----SQGEQSNPAQSPFS 682
Query: 1315 QNPSKHGAIPG--GLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAK---S 1369
+ S H +PG G S P G + + Q+ P S P AVP + +
Sbjct: 683 PHTSPH--LPGIRGPSPSPVGSPA--------SVAQSRSGPLS-PAAVPGNQMPPRPPSG 731
Query: 1370 DSDKI----SNGSSINWPPEF---HPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQ 1422
SD I N SSI + +P +P Q P+ ++P P+G I+T +
Sbjct: 732 QSDSIMHPSMNQSSIAQDRGYMQRNPQMP----QYSSPQPGSALSPRQ-PSGGQIHTGMG 786
Query: 1423 DVNRYLLKS----GGSSPPSSQNATLPSSSAWP---LSASGYSSSFSSIASAPSVAGKLS 1475
+ + S GG P P+ +A P ++G + + + + + G+
Sbjct: 787 SYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAGGQMHGQ-P 845
Query: 1476 DIKSTWSSGPTSHTQASLSH-----ELWKVPRNSTAPTRPPPGLTNPKPSST 1522
I + P + AS+ + + +P + PPPG N K T
Sbjct: 846 GIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQET 897
Score = 37.7 bits (86), Expect = 0.097
Identities = 87/393 (22%), Positives = 122/393 (31%), Gaps = 82/393 (20%)
Query: 16 KTNGNNGTNGALVQSPSNQSALGAGGA--------NSNGSAARVWGVATGSSSGLAHCSV 67
++NG G GA G+GG NSNG+A G ++ L
Sbjct: 78 ESNGGGGGGGA-----------GSGGGPGAEPDLKNSNGNA----GPRPALNNNLTEPPG 122
Query: 68 SGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHE-GTVATGNPSSI 126
GG G D + P++ AA P + G +PS++
Sbjct: 123 GGGGGSSD---------------------GVGAPPHSAAAALPPPAYGFGQPYGRSPSAV 161
Query: 127 CSPVSAI-GQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQN-LNTDGP 184
+ +A+ Q G Q L + G EP QN P + N+ P
Sbjct: 162 AAAAAAVFHQQHGGQQSPGLAALQSGGG----GGLEPYAGPQQNSHDHGFPNHQYNSYYP 217
Query: 185 NNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGSAEGI 244
N + +P + G P G A G+ PP ++ SS +Q G+ G
Sbjct: 218 NRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGG 277
Query: 245 SNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDSGP-- 302
S G P T L+ SSA +G G + GP
Sbjct: 278 GPSAAGGGTPQP---------------TATPTLNQLLTSPSSARGYQGYPGGDYSGGPQD 322
Query: 303 ------PAGPGILAWGRGSGNNGVGNIHSGAWGHPSRS-TSNGVNGEWGKP----PNQHS 351
PA WG + GA + S G +G G+P P S
Sbjct: 323 GGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSS 382
Query: 352 NSDINGK---GSTGWESPSVTSQNPTVQPGGEH 381
D GK G +P Q P P H
Sbjct: 383 PMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGH 415
Score = 37.0 bits (84), Expect = 0.17
Identities = 158/777 (20%), Positives = 253/777 (32%), Gaps = 139/777 (17%)
Query: 15 KKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVAT---------GSSSGLAHC 65
K +NGN G AL + + G GG +S+G A A G G +
Sbjct: 101 KNSNGNAGPRPALNNNLTEPPG-GGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPS 159
Query: 66 SVSGGDGKMDTMIGDGRSQNCWGASNSNAGINLN--LNPNANPAAWPVLGHEGTVATGNP 123
+V+ + G+ A S G L P N H+ N
Sbjct: 160 AVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNR 219
Query: 124 SSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQN-LNTD 182
S+ P A + +G A G+ P S+ +S+S SF+ Q +
Sbjct: 220 SAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSS--SFAQQRFGAMGGG 277
Query: 183 GPN---NTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGG 239
GP+ P ++ +N + T+ G QG PG + S Q GG
Sbjct: 278 GPSAAGGGTPQPTATPTLNQLLTSPSSARG------------YQGYPGGDYSGGPQ-DGG 324
Query: 240 SAEG---ISNSVWGLSPGNPATGNSNSGFSQ-------------GNGD----TVNSALSA 279
+ +G +++ WG + A ++ G Q G G T +
Sbjct: 325 AGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPM 384
Query: 280 KQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHP------SR 333
Q G G+ + GPP+GP +G G G +P ++
Sbjct: 385 DQMGKMRPQPYGGTNPYSQQQGPPSGP-----QQGHGYPGQPYGSQTPQRYPMTMQGRAQ 439
Query: 334 STSNGVNGEWGKPP-NQHSNSDINGKGSTGW---ESP-----------SVTSQNPTVQPG 378
S G++ PP Q S +G T + +SP SQ P QP
Sbjct: 440 SAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPS 499
Query: 379 GEHMNSWAKAASSGTTASEGSSDGSGNHNEGST---GREGTGEGRRRDKGIIDQGHIQLP 435
+ + H + ++ T + + + Q Q P
Sbjct: 500 YQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSP 559
Query: 436 RNDLDPR-----VLSNTG---WGQTPVKQNTAWEFEE-SPRSERKNDNGTEAWGCAATQA 486
P+ LS Q+ Q TA+ + P E D+ A +
Sbjct: 560 YQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMT 619
Query: 487 SNSGGKNDGSIMNSTNTSS---VSGWVNAPPAAVPA-----------NTGWGDSNNKA-- 530
S+ GG+ D ++ + SS +SG ++ P ++ G+ +N A
Sbjct: 620 SSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQS 679
Query: 531 -------PSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWG 583
P PG+ G S S + A S AA P PP+P S
Sbjct: 680 PFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAA-----VPGNQMPPRPPS---- 730
Query: 584 DGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSG---NSG 640
GQ + + + SS+ G ++N S + GS + SG ++G
Sbjct: 731 -GQSDSIMHPS-----MNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSPRQPSGGQIHTG 784
Query: 641 WGN-STNTKANPGTNWGETLKPGPQQNWASKPQDN-----NVSNWGGAASVKQTGTG 691
G+ N+ + G G+ GPQ + +P N N + G A + G G
Sbjct: 785 MGSYQQNSMGSYGPQGGQY---GPQGGYPRQPNYNALPNANYPSAGMAGGINPMGAG 838
Score = 33.1 bits (74), Expect = 2.4
Identities = 61/266 (22%), Positives = 85/266 (31%), Gaps = 45/266 (16%)
Query: 1211 QPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSS---PNTFAPYPLAGL 1267
+PP P PH + P G S +S G+ D S+ N+ P P G
Sbjct: 1161 KPPTPASTPHSQIPPLPGMSRSNSV-------GIQDAFNDGSDSTFQKRNSMTPNP--GY 1211
Query: 1268 NPNMNVNSMDMTGGLSV---KDPSQSQSRLP---------QWTHPNSMDNLPSAASP--- 1312
P+MN + DM G +S KDP S + P Q + D AA P
Sbjct: 1212 QPSMNTS--DMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLG 1269
Query: 1313 -LEQNPSKHGAIPGGL-------SIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSW 1364
+ P +H G IGP G S SP P
Sbjct: 1270 NVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQ 1329
Query: 1365 SRAKSDSDKISNGSSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDV 1424
+ + D N S P G P+ Q + V+ + P N T
Sbjct: 1330 QQQQQRHDSYGNQFSTQGTPS---GSPFPSQQTTMYQQQQQVSSPAPLPRPMENRTSPSK 1386
Query: 1425 NRYL-----LKSGGSSPPSSQNATLP 1445
+ +L ++ G P+S A P
Sbjct: 1387 SPFLHSGMKMQKAGPPVPASHIAPAP 1412
>gi|18644886 forkhead box P1 isoform 1 [Homo sapiens]
Length = 677
Score = 53.9 bits (128), Expect = 1e-06
Identities = 53/161 (32%), Positives = 72/161 (44%), Gaps = 20/161 (12%)
Query: 1082 AQARTMQQPPQPPVQPL-----NSSQPSLRAQV------PQFLSPQVQAQLLQFAAKNIG 1130
A+ +QQ Q V L N QP+L+ V PQ ++PQ Q+LQ
Sbjct: 65 ARQLLLQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQV---- 120
Query: 1131 LNPALLTSPINPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTIT 1190
L+P L + Q ML Q QLQ Y++ Q Q Q+ Q+ +G +++QQVA
Sbjct: 121 LSPQQLQVLLQQQQALMLQQ-QQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQVATQQL 179
Query: 1191 NLQQQIQQHQRQLAQALLVKQPPP----PPPPPHLSLHPSA 1227
QQQ+ Q Q+ Q LL Q P P L L P A
Sbjct: 180 AFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLA 220
>gi|62953127 polyhomeotic 1-like [Homo sapiens]
Length = 1004
Score = 53.5 bits (127), Expect = 2e-06
Identities = 58/227 (25%), Positives = 91/227 (40%), Gaps = 22/227 (9%)
Query: 1035 SLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFGNSGAAQARTMQQPPQPP 1094
SL L + + G + G G Q Q+PS +G G S + + QP P
Sbjct: 261 SLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPSSGMG--GGSCPRKGTGVVQP-LPA 317
Query: 1095 VQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPINPQHMTMLNQLYQL 1154
Q + SQ S Q + +A+ +N+G+N +P Q + Q+
Sbjct: 318 AQTVTVSQGS---QTEAESAAAKKAEADGSGQQNVGMNLTRTATPAPSQTLISSATYTQI 374
Query: 1155 Q-----LAYQRLQIQQQMLQAQRNVSGSMRQQEQ----QVARTITNLQ-------QQIQQ 1198
Q Q++ +QQ+ + Q+ ++ +QQ Q Q+ T T+LQ QQ QQ
Sbjct: 375 QPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATHLQLAQQQQQQQQQQ 434
Query: 1199 HQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLP 1245
Q+Q QA + P PP PP + PS + + P P
Sbjct: 435 QQQQQPQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSP 481
>gi|109255251 loricrin [Homo sapiens]
Length = 312
Score = 52.8 bits (125), Expect = 3e-06
Identities = 49/194 (25%), Positives = 71/194 (36%), Gaps = 7/194 (3%)
Query: 227 GANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSS 286
G GS GG + G + + S G ++G + FS G G A+ + G S
Sbjct: 107 GGGGSGCFSSGGGGSSGGGSGCFS-SGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVS 165
Query: 287 AVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKP 346
+ G G + SG G G G G +G G SG G S+
Sbjct: 166 SGGSSGGGSGCFSSG---GGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQ 222
Query: 347 PNQ-HSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGN 405
P+ +S G G +G S + G + S + G+ GSS G G
Sbjct: 223 PSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGG 282
Query: 406 HNEGSTGREGTGEG 419
+ S G G+G+G
Sbjct: 283 GS--SVGGSGSGKG 294
Score = 49.3 bits (116), Expect = 3e-05
Identities = 53/196 (27%), Positives = 70/196 (35%), Gaps = 16/196 (8%)
Query: 224 GLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNG 283
G G +G SV GG + G + + G +S G S G G S+ +G
Sbjct: 79 GCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSG 138
Query: 284 SSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEW 343
S G GG + + G ++ G GS G G SG G S G +G
Sbjct: 139 GGSGCFSSGGGGFSGQAVQCQSYGGVSSG-GSSGGGSGCFSSGGGGGSVCGYSGGGSGCG 197
Query: 344 GKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGS 403
G +S +G G + + TS P GG SSG S GS S
Sbjct: 198 G------GSSGGSGSGYVSSQQVTQTSCAPQPSYGG---------GSSGGGGSGGSGCFS 242
Query: 404 GNHNEGSTGREGTGEG 419
GS+G G G
Sbjct: 243 SGGGGGSSGCGGGSSG 258
Score = 44.3 bits (103), Expect = 0.001
Identities = 70/323 (21%), Positives = 98/323 (30%), Gaps = 55/323 (17%)
Query: 38 GAGGANSNGSAARVWGVATGSSSGLAHCSVSGGDGKMDTMIGDGRSQNCWGASNSNAGIN 97
G GG + G G +G S + C SGG G G G S G G
Sbjct: 24 GGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGG 83
Query: 98 LNLNPNANPAAWPVLGHEGTVATGNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQ 157
+ + G G ++G S C G + G +G G+ G
Sbjct: 84 SGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGG---- 139
Query: 158 ESTEPQTSTSQNVSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAI 217
+S FS Q + G+ + G + G
Sbjct: 140 ---GSGCFSSGGGGFSGQ--------------------AVQCQSYGGVSSGGSSGGGSGC 176
Query: 218 IPPHLQGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSAL 277
G G SV SGG G G ++G S SG+ +
Sbjct: 177 FS------SGGGGGSVCGYSGG----------GSGCGGGSSGGSGSGY-----------V 209
Query: 278 SAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSN 337
S++Q +S + GG + G G G + G G G++G G SG S
Sbjct: 210 SSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGG 269
Query: 338 GVNGEWGKPPNQHSNSDINGKGS 360
V G G S + G GS
Sbjct: 270 SVCG-GGSSGGGGGGSSVGGSGS 291
Score = 42.0 bits (97), Expect = 0.005
Identities = 50/181 (27%), Positives = 69/181 (38%), Gaps = 27/181 (14%)
Query: 238 GGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNA 297
GGS G S S G S G +G G S G G + GS +V+ G GG++
Sbjct: 40 GGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGG--GGGIGGCGGGSGGSVKYSGGGGSS 97
Query: 298 ------WDSG-------PPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWG 344
+ SG G G G G ++G G G+ G S S+G G G
Sbjct: 98 GGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGG----GSSGGGSGCFSSGGGGFSG 153
Query: 345 KPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSG 404
+ S ++ GS+G S +S G S + G+ GSS GSG
Sbjct: 154 QAVQCQSYGGVSSGGSSGGGSGCFSS--------GGGGGSVCGYSGGGSGCGGGSSGGSG 205
Query: 405 N 405
+
Sbjct: 206 S 206
Score = 36.2 bits (82), Expect = 0.28
Identities = 46/178 (25%), Positives = 58/178 (32%), Gaps = 19/178 (10%)
Query: 254 GNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGR 313
G +G GF G G S+ S G GG + SG G GI G
Sbjct: 25 GGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGS--SGGGGGGGIGGCGG 82
Query: 314 GSGNN------------GVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGST 361
GSG + G G SG G S S+G G G S+ G GS+
Sbjct: 83 GSGGSVKYSGGGGSSGGGSGCFSSGGGG--SGCFSSGGGGSSGGGSGCFSS---GGGGSS 137
Query: 362 GWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGSTGREGTGEG 419
G S +S S+ +S G++ SG G G G G
Sbjct: 138 GGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSG 195
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 52.4 bits (124), Expect = 4e-06
Identities = 45/134 (33%), Positives = 66/134 (49%), Gaps = 9/134 (6%)
Query: 1083 QARTMQQPPQPPVQP----LNSSQPSLRAQV-PQFLSPQVQAQLLQFAAKNIGLNPALLT 1137
Q + ++Q P+P QP L QP L Q PQ Q +QL Q K+ ++ L
Sbjct: 90 QLQQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQ--EKHQSVHHQELK 147
Query: 1138 SPINPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQ 1197
+ H Q Q+Q QRLQ QQ+ LQ Q+ + QQ++Q+ + + QQ +Q
Sbjct: 148 PELQLMHQQQQLQPQQVQ-EQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQE-QQLLQ 205
Query: 1198 QHQRQLAQALLVKQ 1211
Q Q QL Q L++Q
Sbjct: 206 QQQEQLQQQQLLQQ 219
Score = 46.6 bits (109), Expect = 2e-04
Identities = 47/138 (34%), Positives = 59/138 (42%), Gaps = 16/138 (11%)
Query: 1083 QARTMQQPPQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPINP 1142
Q +QQ Q Q L Q L+ Q Q L Q Q Q QF + L
Sbjct: 190 QQEQLQQQVQEQ-QLLQQQQEQLQQQ--QLLQQQEQLQQQQFQQQQEQLQ--------QQ 238
Query: 1143 QHMTMLNQLYQLQ---LAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQQH 1199
Q + +L Q QLQ L Q+ Q+QQQ+L+ Q+ +QQ QQ +QQ
Sbjct: 239 QQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQ 298
Query: 1200 QRQLAQALLVKQPPPPPP 1217
Q QL Q L QPPP P
Sbjct: 299 QEQLQQQQL--QPPPLEP 314
Score = 41.6 bits (96), Expect = 0.007
Identities = 45/143 (31%), Positives = 60/143 (41%), Gaps = 10/143 (6%)
Query: 1083 QARTMQQPPQPPVQPLNSSQPSLRAQVP-QFLSPQVQAQLLQFAAKNIGLNPALLTSPIN 1141
Q + Q Q Q + Q L+ QV Q L Q Q QL Q + + L
Sbjct: 172 QQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQ---QQLLQQQEQLQQQQF 228
Query: 1142 PQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQQHQR 1201
Q L Q QL L Q+ Q+QQQ+LQ Q+ ++QQ L QQ +Q Q+
Sbjct: 229 QQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQ 288
Query: 1202 QLAQALL------VKQPPPPPPP 1218
Q Q LL ++Q PPP
Sbjct: 289 QQQQQLLQQQQEQLQQQQLQPPP 311
Score = 40.0 bits (92), Expect = 0.020
Identities = 54/192 (28%), Positives = 75/192 (39%), Gaps = 16/192 (8%)
Query: 1021 LVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFGNSG 1080
L ++P P L+ P H L Q G Q L+ +Q ++
Sbjct: 94 LEQQPEPQQQPQHEQLQQPQPHLELQQQPQQD-----GQQQLSQLQQEKHQSVHHQELKP 148
Query: 1081 AAQARTMQQPPQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPI 1140
Q QQ QP Q L+ Q Q + Q Q Q Q + L + +
Sbjct: 149 ELQLMHQQQQLQPQQV---QEQQRLQQQQEQLQTQQAQEQ--QVLQQQEQLQQQVQEQQL 203
Query: 1141 NPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQI-QQH 1199
Q QL Q QL Q+ Q+QQQ Q Q+ +QQ+ + + LQQQ+ QQ
Sbjct: 204 LQQQQ---EQLQQQQLLQQQEQLQQQQFQQQQEQL--QQQQQLLLLQQQGQLQQQLLQQQ 258
Query: 1200 QRQLAQALLVKQ 1211
Q QL Q LL +Q
Sbjct: 259 QAQLQQQLLEQQ 270
Score = 39.3 bits (90), Expect = 0.034
Identities = 46/156 (29%), Positives = 63/156 (40%), Gaps = 19/156 (12%)
Query: 1088 QQPPQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPA------LLTSPIN 1141
QQ Q Q L Q L+ Q Q L Q Q QL Q + L P L P++
Sbjct: 269 QQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVD 328
Query: 1142 PQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQQHQR 1201
L Q Q Q L+ QQ+ Q Q + ++Q EQQ+ + QQQ++Q +
Sbjct: 329 LGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQ----QQQLEQQEV 384
Query: 1202 QL---------AQALLVKQPPPPPPPPHLSLHPSAG 1228
QL Q + + P P L L P+AG
Sbjct: 385 QLELTPVELGAQQQEVQLELTPVQPELQLELVPAAG 420
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 52.4 bits (124), Expect = 4e-06
Identities = 66/236 (27%), Positives = 93/236 (39%), Gaps = 26/236 (11%)
Query: 1025 PTPSPF----LPSPSL-KLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFGNS 1079
P+P PF +PSPS + S + P + G+A G G + ++ +G G+
Sbjct: 470 PSPGPFGQEKIPSPSFGQQTFSPQSSP---MPGVAGGSGQSKVMANYMYKAGPSAQGGHL 526
Query: 1080 GAAQARTMQQPPQPPVQP-LNSSQPSLRAQV----PQFLSPQVQAQLLQFAAKNIGLNPA 1134
MQQ PQ + +N+ P++ + P F QA + P+
Sbjct: 527 DVL----MQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPS 582
Query: 1135 LLTSPINPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQ 1194
LL Q Q Q Q Q+ Q QQQ Q Q+ S S +QQ+QQ + QQ
Sbjct: 583 LLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQ 642
Query: 1195 QIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTK 1250
Q QQ Q+Q Q +Q P S P+ S PS P LQ K
Sbjct: 643 QQQQQQQQQQQQQQQQQQQQQQQP---SSQPA------QSLPSQPLLRSPLPLQQK 689
>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
Length = 1745
Score = 52.4 bits (124), Expect = 4e-06
Identities = 69/257 (26%), Positives = 84/257 (32%), Gaps = 43/257 (16%)
Query: 214 MGAIIPPHLQGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTV 273
+G I PP LQGLPG G +V + G + P P G G G
Sbjct: 1141 VGVIGPPGLQGLPGPPGEK-GEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQP- 1198
Query: 274 NSALSAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSR 333
AV ++G G+A D GPP PGI G G SGA G P +
Sbjct: 1199 ------------GAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSG-PSGAAGPPGK 1245
Query: 334 STSNGVNGEWGK-----------PPNQHSNSDINGK-------GSTGWESPSVTSQNPTV 375
G +G G PP S I+G G G P S P
Sbjct: 1246 KGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGA 1305
Query: 376 QPGGEHMNSWAKAASSGTTASEGSSDGSGNHNE----GSTGREGTGEGRRRDKGIIDQGH 431
PG K SG EG G E G GR G R + +G
Sbjct: 1306 -PGPP-----GKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGL 1359
Query: 432 IQLPRNDLDPRVLSNTG 448
+P +P +L G
Sbjct: 1360 RGIPGPVGEPGLLGAPG 1376
Score = 41.6 bits (96), Expect = 0.007
Identities = 60/243 (24%), Positives = 77/243 (31%), Gaps = 52/243 (21%)
Query: 183 GPNNTNPMNSSPNPINAMQTNGLPNWGMAVG-MGAIIPPHLQGLPGANGSSVSQVSGGSA 241
GP P P+ A NG P +G G I P G G G + + S G
Sbjct: 989 GPTGLKGDKGPPGPVGA---NGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGER 1045
Query: 242 --------EGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGS 293
+GI + L P A + G G A +GS
Sbjct: 1046 GPPGPTGKDGIPGPLGPLGPPGAAGPSGEEG----------------DKGDVGAPGHKGS 1089
Query: 294 GGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNS 353
G+ D+GPP PGI G GHP ++G G G P
Sbjct: 1090 KGDKGDAGPPGQPGI----------------RGPAGHPGPPGADGAQGRRGPPGLFGQKG 1133
Query: 354 DINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGSTGR 413
D +G G P P P GE + G+ G+ G +G TG
Sbjct: 1134 DDGVRGFVGVIGPPGLQGLP--GPPGEK----GEVGDVGSMGPHGAPGPRG--PQGPTGS 1185
Query: 414 EGT 416
EGT
Sbjct: 1186 EGT 1188
Score = 40.8 bits (94), Expect = 0.012
Identities = 44/166 (26%), Positives = 56/166 (33%), Gaps = 15/166 (9%)
Query: 183 GPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGSAE 242
GP SP P G+ G G + PP G PG G+ SQ G
Sbjct: 599 GPRGLLGPRGSPGPTGRPGVTGID--GAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQG 656
Query: 243 GISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDSGP 302
I PGNP G +G + G ++G+ G +GP
Sbjct: 657 LIGTPGEKGPPGNPGI----PGLPGSDGPLGHP-------GHEGPTGEKGAQGPPGSAGP 705
Query: 303 PAGPGILAWGRGSGNNGVGNI--HSGAWGHPSRSTSNGVNGEWGKP 346
P PG SGN G+ G G P G+ G+ GKP
Sbjct: 706 PGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKP 751
>gi|48762934 alpha 2 type I collagen [Homo sapiens]
Length = 1366
Score = 51.6 bits (122), Expect = 7e-06
Identities = 142/612 (23%), Positives = 199/612 (32%), Gaps = 107/612 (17%)
Query: 113 GHEGTVATGNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSF 172
G +G+V P+ P+ + G P G +GA GN P P+
Sbjct: 235 GSDGSVGPVGPAG---PIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGL---- 287
Query: 173 SAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSS 232
P + P+ NP NGL A G+ + GLPG G
Sbjct: 288 -----------PGLSGPVGPPGNP----GANGLTGAKGAAGLPGVAGA--PGLPGPRGIP 330
Query: 233 VSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEG 292
V A G V G P G + S GN SA G S K G
Sbjct: 331 -GPVGAAGATGARGLV-----GEP--GPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRG 382
Query: 293 SGGNAWDSGPPAGPGILAWGRGS-GNNGV--GNIHSGAWGHP-SRSTS-----NGVNGEW 343
G A +GPP PG+ RGS G+ G+ + +G G P SR S G NG+
Sbjct: 383 PNGEAGSAGPPGPPGL----RGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDA 438
Query: 344 GKP-----------PNQHSNSDINGK-GSTGWESPSVTSQNPTVQPGGE--HMNSWAKAA 389
G+P P N GK G G P + + + P G +
Sbjct: 439 GRPGEPGLMGPRGLPGSPGNIGPAGKEGPVG--LPGIDGRPGPIGPAGARGEPGNIGFPG 496
Query: 390 SSGTTASEGSSDGSGNHN----------EGSTGREGTGEGRRRDKGIIDQGHIQLPRNDL 439
G T G + G+ +G+ G +G + G +QG P
Sbjct: 497 PKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQG 556
Query: 440 DPRVLSNTGWGQTPVKQNTAWEF----EESPRSERKNDNGTEAWGCAATQASN------- 488
P G P ++ EF PR ER + A G S
Sbjct: 557 LPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPG 616
Query: 489 -SGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTG-WGDSNNKAPSG-PGVWGD--SISS 543
G K + ++ + T+ SG P+ +P G G K G PG+ G+ +
Sbjct: 617 PDGNKGEPGVVGAVGTAGPSG-----PSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGR 671
Query: 544 TAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSS 603
A A +GA ++ G P P G+R AG +A +
Sbjct: 672 DGARGAPGAVGAPGPAGATGDRGEAGAAG-PAGPAGPRGSPGERGE-VGPAGPNGFAGPA 729
Query: 604 SVLGHLG-DGKKNGSGWDADSNRSG----------SGWNDTT-RSGNSGWGNSTNTKANP 651
G G G++ G ++ G +G N +G+ G G P
Sbjct: 730 GAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFP 789
Query: 652 GTNWGETLKPGP 663
G G T PGP
Sbjct: 790 GAA-GRTGPPGP 800
Score = 51.2 bits (121), Expect = 9e-06
Identities = 98/423 (23%), Positives = 132/423 (31%), Gaps = 36/423 (8%)
Query: 14 TKKTNGNNGTNGAL-VQSPSNQSAL-GAGGANSNGSAARVWGVATGSSSGLAHCSVSGGD 71
+K +GN G G+ Q P S G G N +A G G + G D
Sbjct: 353 SKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPG-PPGLRGSPGSRGLPGAD 411
Query: 72 GKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVATGNPSSICSPVS 131
G+ M G S+ G + G N + P G G+ P+ PV
Sbjct: 412 GRAGVM-GPPGSRGASGPAGVR-GPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVG 469
Query: 132 AIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQN--VSFSAQPQNLNTDGPNNTNP 189
G + P G G GN+ P +N + GP+ N
Sbjct: 470 LPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNG 529
Query: 190 MNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGSAEGISNSVW 249
P P G G PP QGLPG +G + +V G+
Sbjct: 530 AQGPPGPQGVQGGKG--------EQGPPGPPGFQGLPGPSGPA-GEVGKPGERGLHGEFG 580
Query: 250 GLSPGNPATGNSNSGFSQGNGDTVNSALSAKQN--------GSSSAVQKEGSGGNAWDSG 301
P P G S G T G V G+ G + SG
Sbjct: 581 LPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSG 640
Query: 302 PPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGST 361
P G G G G + G G+P R + G G G P + D G+
Sbjct: 641 LPGERGAAGIPGGKGEKGEPGLR-GEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAA 699
Query: 362 GWESPSVTSQNP----TVQPGGEHMNSWA-KAASSGTTASEGSSDGSGNHNE----GSTG 412
G P+ +P V P G N +A A ++G ++G G E G TG
Sbjct: 700 GPAGPAGPRGSPGERGEVGPAGP--NGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTG 757
Query: 413 REG 415
G
Sbjct: 758 PVG 760
Score = 48.5 bits (114), Expect = 6e-05
Identities = 64/253 (25%), Positives = 86/253 (33%), Gaps = 32/253 (12%)
Query: 183 GPNNTNPMNSSPNPINAMQTNGLPNW--GMAVGMGAIIPPHLQGLPGANGSSVSQVSGGS 240
GP N + P+ A G PN G A G PP + G PGA G +
Sbjct: 745 GPKGENGVVGPTGPVGAAGPAG-PNGPPGPAGSRGDGGPPGMTGFPGAAG----RTGPPG 799
Query: 241 AEGISNSVWGLSPGNPA-TGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWD 299
GIS PG P G +G+ V G ++G G A
Sbjct: 800 PSGISGP-----PGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGT 854
Query: 300 SGPP---------AGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQH 350
+GPP PGIL G G+ + +GA G P G G G PP
Sbjct: 855 AGPPGTPGPQGLLGAPGILGLPGSRGERGLPGV-AGAVGEPGPLGIAGPPGARG-PPGAV 912
Query: 351 SNSDING-------KGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGS 403
+ +NG G+ G + P P + + + ++G G +
Sbjct: 913 GSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPA 972
Query: 404 GNH-NEGSTGREG 415
G H N G TG G
Sbjct: 973 GKHGNRGETGPSG 985
Score = 43.9 bits (102), Expect = 0.001
Identities = 61/218 (27%), Positives = 78/218 (35%), Gaps = 18/218 (8%)
Query: 220 PHLQGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSA 279
P +G+ G NG + G A G+ G N G + + G V + A
Sbjct: 174 PGFKGIRGHNGLDGLKGQPG-APGVKGEP-GAPGENGTPGQTGARGLPGERGRVGAPGPA 231
Query: 280 KQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNI-HSGAWGHPSRSTSNG 338
GS +V G G +GPP PG A G VGN +G G G
Sbjct: 232 GARGSDGSVGPVGPAGPIGSAGPPGFPG--APGPKGEIGAVGNAGPAGPAGPRGEVGLPG 289
Query: 339 VNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASS-----GT 393
++G G P N +N KG+ G P V P G A A+ G
Sbjct: 290 LSGPVGPPGNPGANGLTGAKGAAG--LPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGE 347
Query: 394 TASEGSSDGSGNHNE-GSTGREGT-----GEGRRRDKG 425
GS SGN E GS G +G EG+R G
Sbjct: 348 PGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNG 385
Score = 41.6 bits (96), Expect = 0.007
Identities = 49/174 (28%), Positives = 61/174 (35%), Gaps = 15/174 (8%)
Query: 204 GLPNWGMAVG----MGAIIPPHLQGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPAT- 258
GLP AVG +G PP +G PGA GS + G A N PG
Sbjct: 883 GLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQP 942
Query: 259 GNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNN 318
G+ GN V +A + +G K G+ G SGP G + SG
Sbjct: 943 GHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQ 1002
Query: 319 GVGNIHSGAWGHPSRSTSNGV------NGEWGKPPNQHSNSDINGKGSTGWESP 366
G+ G G P G+ NG G P + D GS G P
Sbjct: 1003 GI----RGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGP 1052
Score = 35.8 bits (81), Expect = 0.37
Identities = 49/213 (23%), Positives = 69/213 (32%), Gaps = 18/213 (8%)
Query: 219 PPHLQGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALS 278
PP G PG G+ +Q G G+ GL G + + QG
Sbjct: 64 PPGPPGPPGLGGNFAAQYDGKGV-GLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGE 122
Query: 279 AKQNGSSSAVQKEGSGGNAWDSGPPAGP------GILAWGRGSGNNGVGNI--------H 324
Q G + A G G A + G P P G++ G G + H
Sbjct: 123 PGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGH 182
Query: 325 SGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGE-HMN 383
+G G + + GV GE G P + +G G E V + P G + +
Sbjct: 183 NGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPG-ERGRVGAPGPAGARGSDGSVG 241
Query: 384 SWAKAASSGTTASEGSSDGSGNHNE-GSTGREG 415
A G+ G G E G+ G G
Sbjct: 242 PVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAG 274
Score = 33.9 bits (76), Expect = 1.4
Identities = 75/312 (24%), Positives = 97/312 (31%), Gaps = 50/312 (16%)
Query: 15 KKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGV-----ATGSSSGLAHCSVSG 69
K +G GT G +P Q LGA G + G+ A G L G
Sbjct: 846 KGPSGEAGTAGP-PGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPG 904
Query: 70 GDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVATGNPSSICSP 129
G + G + + AG + N + P GH+G G P +I P
Sbjct: 905 ARGPPGAVGSPGVN-----GAPGEAGRDGNPGNDGPPGRDGQPGHKGE--RGYPGNI-GP 956
Query: 130 VSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLNTDGPNNTNP 189
V A G + P G G G P P + GP+
Sbjct: 957 VGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPR-------------GPSGPQG 1003
Query: 190 MNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGSAEGISNSVW 249
+ GLP G+ G LQGLPG G Q G SV
Sbjct: 1004 IRGDKGEPGEKGPRGLP--GLKGHNG------LQGLPGIAGHHGDQ-------GAPGSVG 1048
Query: 250 GLSPGNPA--TGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPPAGPG 307
P PA +G + G+ TV A G +G G GPP PG
Sbjct: 1049 PAGPRGPAGPSGPAGKDGRTGHPGTVGPA------GIRGPQGHQGPAGPPGPPGPPGPPG 1102
Query: 308 ILAWGRGSGNNG 319
+ G G +G
Sbjct: 1103 VSGGGYDFGYDG 1114
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.124 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,479,619
Number of Sequences: 37866
Number of extensions: 4996040
Number of successful extensions: 31038
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 170
Number of HSP's successfully gapped in prelim test: 864
Number of HSP's that attempted gapping in prelim test: 18745
Number of HSP's gapped (non-prelim): 7773
length of query: 1726
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1610
effective length of database: 13,855,062
effective search space: 22306649820
effective search space used: 22306649820
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.