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Search of human proteins with 21717822
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21717822 WAP four-disulfide core domain 5 precursor [Homo
sapiens]
(123 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21717822 WAP four-disulfide core domain 5 precursor [Homo sap... 272 5e-74
gi|4507065 secretory leukocyte peptidase inhibitor precursor [Ho... 73 6e-14
gi|32307109 WAP four-disulfide core domain 3 precursor [Homo sap... 65 1e-11
gi|153946389 WAP four-disulfide core domain 8 precursor [Homo sa... 63 5e-11
gi|153946387 WAP four-disulfide core domain 8 precursor [Homo sa... 63 5e-11
gi|56699495 WAP four-disulfide core domain 2 precursor [Homo sap... 57 3e-09
gi|20069858 WAP four-disulfide core domain 12 precursor [Homo sa... 52 1e-07
gi|4505787 elafin preproprotein [Homo sapiens] 50 4e-07
gi|31563528 serine peptidase inhibitor-like, with Kunitz and WAP... 44 4e-05
gi|119395746 Kallmann syndrome 1 protein precursor [Homo sapiens] 40 4e-04
gi|10732863 serine peptidase inhibitor-like, with Kunitz and WAP... 39 0.001
gi|18379353 WAP four-disulfide core domain 1 precursor [Homo sap... 37 0.003
gi|93102379 low density lipoprotein-related protein 1B precursor... 35 0.019
gi|123173777 keratin associated protein 5-8 [Homo sapiens] 34 0.032
gi|145580584 uromodulin-like 1 isoform 1 precursor [Homo sapiens] 33 0.054
gi|145580582 uromodulin-like 1 isoform 2 precursor [Homo sapiens] 33 0.054
gi|60593036 keratin associated protein 5-3 [Homo sapiens] 33 0.054
gi|239751306 PREDICTED: keratin associated protein 4-8 [Homo sap... 33 0.071
gi|63053512 keratin associated protein 10-1 [Homo sapiens] 33 0.071
gi|4504151 granulin precursor [Homo sapiens] 32 0.093
gi|25121989 sperm mitochondria-associated cysteine-rich protein ... 32 0.12
gi|123702038 keratin associated protein 5-9 [Homo sapiens] 32 0.16
gi|22779936 WAP four-disulfide core domain 6 precursor [Homo sap... 32 0.16
gi|38490571 keratin associated protein 10-7 [Homo sapiens] 32 0.16
gi|225690544 keratin associated protein 4-11 [Homo sapiens] 31 0.27
gi|66346695 fibrillin 2 precursor [Homo sapiens] 31 0.27
gi|13994129 keratin associated protein 4-12 [Homo sapiens] 31 0.27
gi|21703706 WAP four-disulfide core domain 10A precursor [Homo s... 31 0.27
gi|19743803 fibulin 5 precursor [Homo sapiens] 30 0.35
gi|239751308 PREDICTED: keratin associated protein 4-9 isoform 1... 30 0.35
>gi|21717822 WAP four-disulfide core domain 5 precursor [Homo
sapiens]
Length = 123
Score = 272 bits (695), Expect = 5e-74
Identities = 123/123 (100%), Positives = 123/123 (100%)
Query: 1 MRTQSLLLLGALLAVGSQLPAVFGRKKGEKSGGCPPDDGPCLLSVPDQCVEDSQCPLTRK 60
MRTQSLLLLGALLAVGSQLPAVFGRKKGEKSGGCPPDDGPCLLSVPDQCVEDSQCPLTRK
Sbjct: 1 MRTQSLLLLGALLAVGSQLPAVFGRKKGEKSGGCPPDDGPCLLSVPDQCVEDSQCPLTRK 60
Query: 61 CCYRACFRQCVPRVSVKLGSCPEDQLRCLSPMNHLCHKDSDCSGKKRCCHSACGRDCRDP 120
CCYRACFRQCVPRVSVKLGSCPEDQLRCLSPMNHLCHKDSDCSGKKRCCHSACGRDCRDP
Sbjct: 61 CCYRACFRQCVPRVSVKLGSCPEDQLRCLSPMNHLCHKDSDCSGKKRCCHSACGRDCRDP 120
Query: 121 ARG 123
ARG
Sbjct: 121 ARG 123
>gi|4507065 secretory leukocyte peptidase inhibitor precursor [Homo
sapiens]
Length = 132
Score = 72.8 bits (177), Expect = 6e-14
Identities = 45/132 (34%), Positives = 60/132 (45%), Gaps = 11/132 (8%)
Query: 1 MRTQSLLLLGALLAVGSQLP-AVFGRKKGEKSGGCPPD-DGPCLLSVPDQCVEDSQCPLT 58
M++ L LLA+G+ P AV G K K+G CPP CL +C D QCP
Sbjct: 1 MKSSGLFPFLVLLALGTLAPWAVEGSGKSFKAGVCPPKKSAQCLRYKKPECQSDWQCPGK 60
Query: 59 RKCCYRACFRQCVPRVSV------KLGSCPEDQLRC--LSPMNHLCHKDSDCSGKKRCCH 110
++CC C +C+ V K G CP +C L+P N C D C +CC
Sbjct: 61 KRCCPDTCGIKCLDPVDTPNPTRRKPGKCPVTYGQCLMLNPPN-FCEMDGQCKRDLKCCM 119
Query: 111 SACGRDCRDPAR 122
CG+ C P +
Sbjct: 120 GMCGKSCVSPVK 131
>gi|32307109 WAP four-disulfide core domain 3 precursor [Homo
sapiens]
Length = 231
Score = 65.1 bits (157), Expect = 1e-11
Identities = 42/122 (34%), Positives = 51/122 (41%), Gaps = 11/122 (9%)
Query: 1 MRTQSLLLLGALLAVGSQLPAVFGRKKGEKSGGCPPDDGPCLLSVPDQCVEDSQCPLTRK 60
M L LL ALLA+GS L + + K G CPP PC + C D CP +K
Sbjct: 1 MMLSCLFLLKALLALGS-LESWITAGEHAKEGECPPHKNPC----KELCQGDELCPAEQK 55
Query: 61 CCYRACFRQCVPRVSVKLGSCPE--DQLRCLSPMNHLCHKDSDCSGKKRCCHSACGRDCR 118
CC C R C + CP + CL C D C G K+CC C + C
Sbjct: 56 CCTTGCGRICRDIPKGRKRDCPRVIRKQSCLK----RCITDETCPGVKKCCTLGCNKSCV 111
Query: 119 DP 120
P
Sbjct: 112 VP 113
Score = 58.5 bits (140), Expect = 1e-09
Identities = 33/98 (33%), Positives = 45/98 (45%), Gaps = 10/98 (10%)
Query: 25 RKKGEKSGGCPPDDGPCLLSVPDQCVEDSQCPLTRKCCYRACFRQCVPRVSV-KLGSCPE 83
+K E G CP D PC + C D+ CP KCC C R C+ + + G CP+
Sbjct: 117 QKLAEFGGECPADPLPC----EELCDGDASCPQGHKCCSTGCGRTCLGDIEGGRGGDCPK 172
Query: 84 DQLR-CLSPMNHLCHKDSDCSGKKRCCHSACGRDCRDP 120
+ C+ C D +C ++CC S CGR C P
Sbjct: 173 VLVGLCIVG----CVMDENCQAGEKCCKSGCGRFCVPP 206
Score = 42.4 bits (98), Expect = 9e-05
Identities = 18/47 (38%), Positives = 25/47 (53%), Gaps = 4/47 (8%)
Query: 77 KLGSCPEDQLRCLSPMNHLCHKDSDCSGKKRCCHSACGRDCRDPARG 123
K G CP + +P LC D C +++CC + CGR CRD +G
Sbjct: 29 KEGECPPHK----NPCKELCQGDELCPAEQKCCTTGCGRICRDIPKG 71
Score = 36.2 bits (82), Expect = 0.006
Identities = 20/52 (38%), Positives = 24/52 (46%), Gaps = 5/52 (9%)
Query: 24 GRKKGEKSGGCPPD-DGPCLLSVPDQCVEDSQCPLTRKCCYRACFRQCVPRV 74
G +G + G CP G C++ CV D C KCC C R CVP V
Sbjct: 160 GDIEGGRGGDCPKVLVGLCIVG----CVMDENCQAGEKCCKSGCGRFCVPPV 207
>gi|153946389 WAP four-disulfide core domain 8 precursor [Homo
sapiens]
Length = 241
Score = 63.2 bits (152), Expect = 5e-11
Identities = 34/93 (36%), Positives = 39/93 (41%), Gaps = 1/93 (1%)
Query: 30 KSGGCPPDDGPCLLSVPDQCVEDSQCPLTRKCCYRACFRQCVPRVSVKLGSCPEDQLRCL 89
K G CP P C D CP T KCC C C +VK G CP L C
Sbjct: 150 KDGQCPLFPFTERKECPPSCHSDIDCPQTDKCCESRCGFVCARAWTVKKGFCPRKPLLCT 209
Query: 90 SPMNHLCHKDSDCSGKKRCCHSACGRDCRDPAR 122
C +D +C ++CC S CG C DP R
Sbjct: 210 KIDKPKCLQDEECPLVEKCC-SHCGLKCMDPRR 241
Score = 48.9 bits (115), Expect = 1e-06
Identities = 41/168 (24%), Positives = 56/168 (33%), Gaps = 59/168 (35%)
Query: 6 LLLLGALLAVGSQLPAVFGRKKGEKSGGCPPDDGPCLLSVPDQCVEDSQCPLTRKCCYRA 65
LLLL L S A+ +K K G CP + C +PD C D C +KCC+ A
Sbjct: 26 LLLLSLALEWTS---AMLTKKIKHKPGLCPKERLTCTTELPDSCNTDFDCKEYQKCCFFA 82
Query: 66 CFRQCVP------RVSVKLGSCPEDQLR-----------------CLSPMNHL------- 95
C ++C+ + V+ G+C + R C N+
Sbjct: 83 CQKKCMDPFQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACR 142
Query: 96 --------------------------CHKDSDCSGKKRCCHSACGRDC 117
CH D DC +CC S CG C
Sbjct: 143 TACMLIVKDGQCPLFPFTERKECPPSCHSDIDCPQTDKCCESRCGFVC 190
Score = 47.4 bits (111), Expect = 3e-06
Identities = 17/48 (35%), Positives = 28/48 (58%)
Query: 73 RVSVKLGSCPEDQLRCLSPMNHLCHKDSDCSGKKRCCHSACGRDCRDP 120
++ K G CP+++L C + + C+ D DC ++CC AC + C DP
Sbjct: 43 KIKHKPGLCPKERLTCTTELPDSCNTDFDCKEYQKCCFFACQKKCMDP 90
>gi|153946387 WAP four-disulfide core domain 8 precursor [Homo
sapiens]
Length = 241
Score = 63.2 bits (152), Expect = 5e-11
Identities = 34/93 (36%), Positives = 39/93 (41%), Gaps = 1/93 (1%)
Query: 30 KSGGCPPDDGPCLLSVPDQCVEDSQCPLTRKCCYRACFRQCVPRVSVKLGSCPEDQLRCL 89
K G CP P C D CP T KCC C C +VK G CP L C
Sbjct: 150 KDGQCPLFPFTERKECPPSCHSDIDCPQTDKCCESRCGFVCARAWTVKKGFCPRKPLLCT 209
Query: 90 SPMNHLCHKDSDCSGKKRCCHSACGRDCRDPAR 122
C +D +C ++CC S CG C DP R
Sbjct: 210 KIDKPKCLQDEECPLVEKCC-SHCGLKCMDPRR 241
Score = 48.9 bits (115), Expect = 1e-06
Identities = 41/168 (24%), Positives = 56/168 (33%), Gaps = 59/168 (35%)
Query: 6 LLLLGALLAVGSQLPAVFGRKKGEKSGGCPPDDGPCLLSVPDQCVEDSQCPLTRKCCYRA 65
LLLL L S A+ +K K G CP + C +PD C D C +KCC+ A
Sbjct: 26 LLLLSLALEWTS---AMLTKKIKHKPGLCPKERLTCTTELPDSCNTDFDCKEYQKCCFFA 82
Query: 66 CFRQCVP------RVSVKLGSCPEDQLR-----------------CLSPMNHL------- 95
C ++C+ + V+ G+C + R C N+
Sbjct: 83 CQKKCMDPFQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACR 142
Query: 96 --------------------------CHKDSDCSGKKRCCHSACGRDC 117
CH D DC +CC S CG C
Sbjct: 143 TACMLIVKDGQCPLFPFTERKECPPSCHSDIDCPQTDKCCESRCGFVC 190
Score = 47.4 bits (111), Expect = 3e-06
Identities = 17/48 (35%), Positives = 28/48 (58%)
Query: 73 RVSVKLGSCPEDQLRCLSPMNHLCHKDSDCSGKKRCCHSACGRDCRDP 120
++ K G CP+++L C + + C+ D DC ++CC AC + C DP
Sbjct: 43 KIKHKPGLCPKERLTCTTELPDSCNTDFDCKEYQKCCFFACQKKCMDP 90
>gi|56699495 WAP four-disulfide core domain 2 precursor [Homo
sapiens]
Length = 124
Score = 57.4 bits (137), Expect = 3e-09
Identities = 39/115 (33%), Positives = 50/115 (43%), Gaps = 18/115 (15%)
Query: 5 SLLLLGALLAVGSQLPAVFGRKKGEKSGGCPP--DDGPCLLSVPDQCVEDSQCPLTRKCC 62
SLLL G L G+ EK+G CP D C +CV DS+C KCC
Sbjct: 16 SLLLFGFTLVSGTG---------AEKTGVCPELQADQNCT----QECVSDSECADNLKCC 62
Query: 63 YRACFRQCVPRVSVKLGSCPEDQLRC--LSPMNHLCHKDSDCSGKKRCCHSACGR 115
C C + K GSCP+ + L C DS C G+ +CC + CG+
Sbjct: 63 SAGCATFC-SLPNDKEGSCPQVNINFPQLGLCRDQCQVDSQCPGQMKCCRNGCGK 116
Score = 32.3 bits (72), Expect = 0.093
Identities = 15/44 (34%), Positives = 20/44 (45%), Gaps = 2/44 (4%)
Query: 77 KLGSCPEDQLRCLSPMNHLCHKDSDCSGKKRCCHSACGRDCRDP 120
K G CPE L+ C DS+C+ +CC + C C P
Sbjct: 32 KTGVCPE--LQADQNCTQECVSDSECADNLKCCSAGCATFCSLP 73
>gi|20069858 WAP four-disulfide core domain 12 precursor [Homo
sapiens]
Length = 111
Score = 52.0 bits (123), Expect = 1e-07
Identities = 31/67 (46%), Positives = 39/67 (58%), Gaps = 3/67 (4%)
Query: 6 LLLLGALLAVGSQLPAVFGRKKG-EKSGGCPPDDGPCLLSVPDQCVEDSQCPLTRKCCYR 64
L+L+ +L+ V L AV G K+G EK+G CP D+ C S P QC D C RKCCY
Sbjct: 7 LVLMVSLVLV--TLVAVEGVKEGIEKAGVCPADNVRCFKSDPPQCHTDQDCLGERKCCYL 64
Query: 65 ACFRQCV 71
C +CV
Sbjct: 65 HCGFKCV 71
Score = 50.4 bits (119), Expect = 3e-07
Identities = 19/46 (41%), Positives = 25/46 (54%)
Query: 77 KLGSCPEDQLRCLSPMNHLCHKDSDCSGKKRCCHSACGRDCRDPAR 122
K G CP D +RC CH D DC G+++CC+ CG C P +
Sbjct: 30 KAGVCPADNVRCFKSDPPQCHTDQDCLGERKCCYLHCGFKCVIPVK 75
>gi|4505787 elafin preproprotein [Homo sapiens]
Length = 117
Score = 50.1 bits (118), Expect = 4e-07
Identities = 25/49 (51%), Positives = 30/49 (61%), Gaps = 3/49 (6%)
Query: 74 VSVKLGSCPEDQLRC--LSPMNHLCHKDSDCSGKKRCCHSACGRDCRDP 120
VS K GSCP +RC L+P N C KD+DC G K+CC +CG C P
Sbjct: 69 VSTKPGSCPIILIRCAMLNPPNR-CLKDTDCPGIKKCCEGSCGMACFVP 116
Score = 37.4 bits (85), Expect = 0.003
Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 1/42 (2%)
Query: 30 KSGGCPPDDGPC-LLSVPDQCVEDSQCPLTRKCCYRACFRQC 70
K G CP C +L+ P++C++D+ CP +KCC +C C
Sbjct: 72 KPGSCPIILIRCAMLNPPNRCLKDTDCPGIKKCCEGSCGMAC 113
>gi|31563528 serine peptidase inhibitor-like, with Kunitz and WAP
domains 1 isoform 2 [Homo sapiens]
Length = 117
Score = 43.5 bits (101), Expect = 4e-05
Identities = 16/47 (34%), Positives = 25/47 (53%)
Query: 73 RVSVKLGSCPEDQLRCLSPMNHLCHKDSDCSGKKRCCHSACGRDCRD 119
+ ++ LG CP+ + C +C KD C K+CC +CG+ C D
Sbjct: 9 KTALSLGRCPKIREECEFQERDVCTKDRQCQDNKKCCVFSCGKKCLD 55
Score = 41.6 bits (96), Expect = 2e-04
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 7/89 (7%)
Query: 19 LPAVFGRKKGEKSGGCPPDDGPCLLSVPDQCVEDSQCPLTRKCCYRACFRQCVPRVSVKL 78
L G K G CP C D C +D QC +KCC +C ++C + +K
Sbjct: 2 LSKAHGCKTALSLGRCPKIREECEFQERDVCTKDRQCQDNKKCCVFSCGKKC---LDLKQ 58
Query: 79 GSC--PEDQLRCLSPMNHLCH--KDSDCS 103
C P++ CL+ H + KD+ CS
Sbjct: 59 DVCEMPKETGPCLAYFLHWWYDKKDNTCS 87
>gi|119395746 Kallmann syndrome 1 protein precursor [Homo sapiens]
Length = 680
Score = 40.0 bits (92), Expect = 4e-04
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Query: 76 VKLGSCP--EDQLRCLSPMNHLCHKDSDCSGKKRCCHSACGRDCRDP 120
VK G CP E + C D++CSG K+CC + CG C+ P
Sbjct: 129 VKQGDCPAPEKASGFAAACVESCEVDNECSGVKKCCSNGCGHTCQVP 175
Score = 29.6 bits (65), Expect = 0.60
Identities = 15/51 (29%), Positives = 22/51 (43%), Gaps = 3/51 (5%)
Query: 30 KSGGCPPDDGPCLLSVP--DQCVEDSQCPLTRKCCYRACFRQC-VPRVSVK 77
K G CP + + + C D++C +KCC C C VP+ K
Sbjct: 130 KQGDCPAPEKASGFAAACVESCEVDNECSGVKKCCSNGCGHTCQVPKTLYK 180
>gi|10732863 serine peptidase inhibitor-like, with Kunitz and WAP
domains 1 isoform 1 precursor [Homo sapiens]
Length = 133
Score = 38.9 bits (89), Expect = 0.001
Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 7/74 (9%)
Query: 34 CPPDDGPCLLSVPDQCVEDSQCPLTRKCCYRACFRQCVPRVSVKLGSC--PEDQLRCLSP 91
CP C D C +D QC +KCC +C ++C + +K C P++ CL+
Sbjct: 33 CPKIREECEFQERDVCTKDRQCQDNKKCCVFSCGKKC---LDLKQDVCEMPKETGPCLAY 89
Query: 92 MNHLCH--KDSDCS 103
H + KD+ CS
Sbjct: 90 FLHWWYDKKDNTCS 103
Score = 38.5 bits (88), Expect = 0.001
Identities = 14/39 (35%), Positives = 20/39 (51%)
Query: 81 CPEDQLRCLSPMNHLCHKDSDCSGKKRCCHSACGRDCRD 119
CP+ + C +C KD C K+CC +CG+ C D
Sbjct: 33 CPKIREECEFQERDVCTKDRQCQDNKKCCVFSCGKKCLD 71
>gi|18379353 WAP four-disulfide core domain 1 precursor [Homo
sapiens]
Length = 220
Score = 37.4 bits (85), Expect = 0.003
Identities = 29/95 (30%), Positives = 37/95 (38%), Gaps = 27/95 (28%)
Query: 4 QSLLLLGALLAVGSQ-------LPAVFGRKKGEKSGG------------CPPDD-----G 39
++L LL LL GS LPA K + G CPP G
Sbjct: 17 RALCLLLLLLHAGSAKNIWKRALPARLAEKSRAEEAGAPGGPRQPRADRCPPPPRTLPPG 76
Query: 40 PCLLSVPDQCVEDSQCPLTRKCCYRACFRQCVPRV 74
C + +C DS+CP R+CCY C C+ V
Sbjct: 77 ACQAA---RCQADSECPRHRRCCYNGCAYACLEAV 108
Score = 30.4 bits (67), Expect = 0.35
Identities = 9/22 (40%), Positives = 13/22 (59%)
Query: 96 CHKDSDCSGKKRCCHSACGRDC 117
C DS+C +RCC++ C C
Sbjct: 83 CQADSECPRHRRCCYNGCAYAC 104
>gi|93102379 low density lipoprotein-related protein 1B precursor
[Homo sapiens]
Length = 4599
Score = 34.7 bits (78), Expect = 0.019
Identities = 33/113 (29%), Positives = 44/113 (38%), Gaps = 29/113 (25%)
Query: 25 RKKGEKSGGCPPDDGPCLLSVPDQCVEDSQC-------PLTRKCCYRACFRQCVPRVSVK 77
R+ G + C DG CLL+ QC D C PL KC ++ + C +
Sbjct: 2843 RQCGTEEFSCA--DGRCLLNTQWQCDGDFDCPDHSDEAPLNPKC--KSAEQSC----NSS 2894
Query: 78 LGSCPEDQLRCLSPMNHLCHKDSDC--SGKKRCCH---------SACGRDCRD 119
C RC+ P LC DC +R CH S C +DC+D
Sbjct: 2895 FFMCKNG--RCI-PSGGLCDNKDDCGDGSDERNCHINECLSKKVSGCSQDCQD 2944
Score = 28.5 bits (62), Expect = 1.3
Identities = 14/44 (31%), Positives = 21/44 (47%), Gaps = 5/44 (11%)
Query: 80 SCPEDQLRCLS----PMNHLCHKDSDCSGKKRCCHSAC-GRDCR 118
SCP+DQ +C + P LC +DC + + C R C+
Sbjct: 885 SCPDDQFKCQNNRCIPKRWLCDGANDCGSNEDESNQTCTARTCQ 928
>gi|123173777 keratin associated protein 5-8 [Homo sapiens]
Length = 187
Score = 33.9 bits (76), Expect = 0.032
Identities = 31/105 (29%), Positives = 37/105 (35%), Gaps = 17/105 (16%)
Query: 24 GRKKGEKSGGCPPDDGPCLLSVPDQCVEDSQCPLTR----KCCYRACFRQCVPRVSV-KL 78
G KG+ G C G C QC C + CC +C + C + S K
Sbjct: 64 GGSKGD-CGSCGGSKGGCGSCGCSQCSCYKPCCCSSGCGSSCCQSSCCKPCCSQSSCCKP 122
Query: 79 GSCPED------QLRCLSPMNHLCHKDSDCSGKKRCCHSACGRDC 117
SC Q C P C + S C K CC S CG C
Sbjct: 123 CSCSSGCGSSCCQSSCCKPC---CSQSSCC--KPCCCSSGCGSSC 162
>gi|145580584 uromodulin-like 1 isoform 1 precursor [Homo sapiens]
Length = 1318
Score = 33.1 bits (74), Expect = 0.054
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 3/43 (6%)
Query: 79 GSCPEDQLRCLSPMNHLCHKDSDCSGKKRCCHSACGRDCRDPA 121
G+CP + P C D DC G ++CC + GR C PA
Sbjct: 119 GACPAEGPE---PSTSPCSLDIDCPGLEKCCPWSGGRYCMAPA 158
>gi|145580582 uromodulin-like 1 isoform 2 precursor [Homo sapiens]
Length = 1446
Score = 33.1 bits (74), Expect = 0.054
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 3/43 (6%)
Query: 79 GSCPEDQLRCLSPMNHLCHKDSDCSGKKRCCHSACGRDCRDPA 121
G+CP + P C D DC G ++CC + GR C PA
Sbjct: 119 GACPAEGPE---PSTSPCSLDIDCPGLEKCCPWSGGRYCMAPA 158
>gi|60593036 keratin associated protein 5-3 [Homo sapiens]
Length = 238
Score = 33.1 bits (74), Expect = 0.054
Identities = 30/91 (32%), Positives = 32/91 (35%), Gaps = 20/91 (21%)
Query: 27 KGEKSGGCPPDDGPCLLSVPDQCVEDSQCPLTRKCCYRACFRQCVPRVSVKLGSCPEDQL 86
+G GGC G C S QC C CC C C K SC Q
Sbjct: 114 RGGSKGGC----GSCGCS---QCSCYKPC-----CCSSGCGSSCCQSSCCK-PSC--SQS 158
Query: 87 RCLSPMNHLCHKDSDCSGKKRCCHSACGRDC 117
C P C + S C K CC S CG C
Sbjct: 159 SCCKPC---CSQSSCC--KPCCCSSGCGSSC 184
Score = 30.4 bits (67), Expect = 0.35
Identities = 30/105 (28%), Positives = 36/105 (34%), Gaps = 18/105 (17%)
Query: 24 GRKKGEKSGGCPPDD--GPCLLS--VPDQCVEDSQCPLTRKCCYRACFRQCVPRVSVKLG 79
G K G S GC PC S C + S C + C +C + C + S
Sbjct: 116 GSKGGCGSCGCSQCSCYKPCCCSSGCGSSCCQSSCCKPS--CSQSSCCKPCCSQSSCCKP 173
Query: 80 SCPED-------QLRCLSPMNHLCHKDSDCSGKKRCCHSACGRDC 117
C Q C P C + S C K CC S CG C
Sbjct: 174 CCCSSGCGSSCCQSSCCKPC---CSQSSCC--KPCCCSSGCGSSC 213
>gi|239751306 PREDICTED: keratin associated protein 4-8 [Homo
sapiens]
Length = 195
Score = 32.7 bits (73), Expect = 0.071
Identities = 23/75 (30%), Positives = 30/75 (40%), Gaps = 9/75 (12%)
Query: 48 QCVEDSQCPLTRKCCYRACFRQCVPRVSVKLGSCPEDQLR---CLSPMNHLCHKDSDCSG 104
QC + C T CC+ +C R S + SC + Q C P CH S
Sbjct: 88 QCCQSVCCQPT--CCHPSCCISSCCRPSCCVSSCCKPQCCQSVCCQPT--CCHPSCSISS 143
Query: 105 --KKRCCHSACGRDC 117
+ CC S+C R C
Sbjct: 144 CCRPSCCESSCCRPC 158
>gi|63053512 keratin associated protein 10-1 [Homo sapiens]
Length = 282
Score = 32.7 bits (73), Expect = 0.071
Identities = 25/88 (28%), Positives = 30/88 (34%), Gaps = 13/88 (14%)
Query: 40 PCLLSVPDQCVEDSQCPLTRKCCYRACFRQCVPRVSVKLGSCPEDQLRCLSPMNHLCHKD 99
P C + S C CC +C C P SV L P + C P++ C
Sbjct: 201 PVCSGASTSCCQQSSCQPA--CCTTSC---CRPSSSVSLLCRPVCRPACCMPVSSCCAPA 255
Query: 100 SDCSGKKRCCHSA------CGRDCRDPA 121
S C CC A C C PA
Sbjct: 256 SSCQAS--CCRPASCVSLLCRPACSRPA 281
Score = 30.0 bits (66), Expect = 0.46
Identities = 24/108 (22%), Positives = 35/108 (32%), Gaps = 30/108 (27%)
Query: 36 PDDGPCLLSVPDQCVEDSQC--------PLTRKCCYRACFRQ--CVPRVSVKLGSCPEDQ 85
P C S C + S C P + CC C + C+P S SC +
Sbjct: 66 PCQSGCTSSCTPSCCQQSSCQPACCTSSPCQQACCVPVCCKPVCCLPTCSKDSSSCCQQS 125
Query: 86 LR------------------CLSPMNHL--CHKDSDCSGKKRCCHSAC 113
C P+ ++ C +DS ++ CH AC
Sbjct: 126 SCQPTCCASSSSQQSCCVPVCCKPVCYVPTCSEDSSSCCQQSSCHPAC 173
>gi|4504151 granulin precursor [Homo sapiens]
Length = 593
Score = 32.3 bits (72), Expect = 0.093
Identities = 21/80 (26%), Positives = 29/80 (36%), Gaps = 17/80 (21%)
Query: 37 DDGPCLLSVPDQ--------CVEDSQCPLTRKCCYRACFRQCVPRVSVKLGSCPEDQLRC 88
+ P LS+PD C S CP + CC S + G CP + C
Sbjct: 346 EKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLT---------SGEWGCCPIPEAVC 396
Query: 89 LSPMNHLCHKDSDCSGKKRC 108
S H C + C + +C
Sbjct: 397 CSDHQHCCPQGYTCVAEGQC 416
Score = 29.3 bits (64), Expect = 0.79
Identities = 19/69 (27%), Positives = 23/69 (33%), Gaps = 2/69 (2%)
Query: 34 CPPDDGPCLLSVPDQCVEDSQCPLTRKCCYRACFRQCVPRVSVKLGSCPEDQLRCLSPMN 93
C D C + V QCP ++ C F C V G CP Q C
Sbjct: 105 CSADGRSCFQRSGNNSVGAIQCPDSQFEC--PDFSTCCVMVDGSWGCCPMPQASCCEDRV 162
Query: 94 HLCHKDSDC 102
H C + C
Sbjct: 163 HCCPHGAFC 171
Score = 28.1 bits (61), Expect = 1.8
Identities = 16/48 (33%), Positives = 18/48 (37%), Gaps = 2/48 (4%)
Query: 55 CPLTRKCCYRACFRQCVPRVSVKLGSCPEDQLRCLSPMNHLCHKDSDC 102
CP R C C S K G CP C S H C +D+ C
Sbjct: 208 CPDARSRCPDGS--TCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVC 253
Score = 28.1 bits (61), Expect = 1.8
Identities = 14/61 (22%), Positives = 20/61 (32%), Gaps = 9/61 (14%)
Query: 49 CVEDSQCPLTRKCCYRACFRQCVPRVSVKLGSCPEDQLRCLSPMNHLCHKDSDCSGKKRC 108
C + + CP+ + CC P + C C H C C+ K R
Sbjct: 444 CDQHTSCPVGQTCC---------PSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARS 494
Query: 109 C 109
C
Sbjct: 495 C 495
Score = 27.3 bits (59), Expect = 3.0
Identities = 20/70 (28%), Positives = 24/70 (34%), Gaps = 7/70 (10%)
Query: 42 LLSVPDQCVEDSQCPLTRKCC--YRACFRQCVPRVSVKLGSCPEDQLRCLSPMNHLCHKD 99
L +P V D +C + C Y C Q S G CP Q C H C
Sbjct: 271 LTKLPAHTVGDVKCDMEVSCPDGYTCCRLQ-----SGAWGCCPFTQAVCCEDHIHCCPAG 325
Query: 100 SDCSGKKRCC 109
C +K C
Sbjct: 326 FTCDTQKGTC 335
>gi|25121989 sperm mitochondria-associated cysteine-rich protein
[Homo sapiens]
Length = 116
Score = 32.0 bits (71), Expect = 0.12
Identities = 21/76 (27%), Positives = 25/76 (32%), Gaps = 22/76 (28%)
Query: 34 CPPDDGPCLLSVPDQCVEDSQCPLTRKCCYRACFRQCVPRVSVKLGSCPEDQLRCLSPMN 93
CPP C S +QC CP + C + QC CP N
Sbjct: 19 CPPQQNQCCQSKGNQC-----CPPKQNQCCQPKGSQC----------CPPKH-------N 56
Query: 94 HLCHKDSDCSGKKRCC 109
H C C + RCC
Sbjct: 57 HCCQPKPPCCIQARCC 72
>gi|123702038 keratin associated protein 5-9 [Homo sapiens]
Length = 169
Score = 31.6 bits (70), Expect = 0.16
Identities = 28/93 (30%), Positives = 30/93 (32%), Gaps = 10/93 (10%)
Query: 28 GEKSGGCPPDDGPC---LLSVPDQCVEDSQCPLTRKCCYRACFRQCVPRVSVKLGSCPED 84
G GGC G C C C CC AC C GSC
Sbjct: 11 GSSCGGCDSSCGSCGSGCRGCGPSCCAPVYCCKPVCCCVPAC--SCSSCGKRGCGSCGGS 68
Query: 85 QLRCLSPMNHLCHKDSDCSGKKRCCHSACGRDC 117
+ C S C + S C K CC S CG C
Sbjct: 69 KGGCGSCG---CSQCSCC--KPCCCSSGCGSSC 96
Score = 27.3 bits (59), Expect = 3.0
Identities = 29/104 (27%), Positives = 36/104 (34%), Gaps = 17/104 (16%)
Query: 24 GRKKGEKSGGCPPDD--GPCLLS--VPDQCVEDSQC-PLTRKCCYRACFRQCVPRVSVKL 78
G K G S GC PC S C + S C P +C +C + C
Sbjct: 67 GSKGGCGSCGCSQCSCCKPCCCSSGCGSSCCQCSCCKPYCSQC---SCCKPCCSSSGRGS 123
Query: 79 GSCPEDQLRCLSPMNHLCHKDSDCSGKKRCCHSACGRDCRDPAR 122
C Q C P C S C CC S+C + C +R
Sbjct: 124 SCC---QSSCCKP----CCSSSGCGSS--CCQSSCCKPCCSQSR 158
>gi|22779936 WAP four-disulfide core domain 6 precursor [Homo
sapiens]
Length = 86
Score = 31.6 bits (70), Expect = 0.16
Identities = 17/63 (26%), Positives = 27/63 (42%)
Query: 24 GRKKGEKSGGCPPDDGPCLLSVPDQCVEDSQCPLTRKCCYRACFRQCVPRVSVKLGSCPE 83
G +G CP C + DQC + CP KCC + ++C+ V L +
Sbjct: 23 GHAEGILGKPCPKIKVECEVEEIDQCTKPRDCPENMKCCPFSRGKKCLDFRKVSLTLYHK 82
Query: 84 DQL 86
++L
Sbjct: 83 EEL 85
Score = 30.0 bits (66), Expect = 0.46
Identities = 12/39 (30%), Positives = 18/39 (46%)
Query: 81 CPEDQLRCLSPMNHLCHKDSDCSGKKRCCHSACGRDCRD 119
CP+ ++ C C K DC +CC + G+ C D
Sbjct: 33 CPKIKVECEVEEIDQCTKPRDCPENMKCCPFSRGKKCLD 71
>gi|38490571 keratin associated protein 10-7 [Homo sapiens]
Length = 370
Score = 31.6 bits (70), Expect = 0.16
Identities = 25/88 (28%), Positives = 29/88 (32%), Gaps = 13/88 (14%)
Query: 40 PCLLSVPDQCVEDSQCPLTRKCCYRACFRQCVPRVSVKLGSCPEDQLRCLSPMNHLCHKD 99
P C + S C CC +C C P SV L P + C P+ C
Sbjct: 278 PVCSGASTSCCQQSSCQPA--CCTTSC---CRPSSSVSLLCRPVCRPACCVPVPSCCAPT 332
Query: 100 SDCSGKKRCCHSA------CGRDCRDPA 121
S C CC A C C PA
Sbjct: 333 SSCQAS--CCRPASCVSLLCRPACSRPA 358
>gi|225690544 keratin associated protein 4-11 [Homo sapiens]
Length = 195
Score = 30.8 bits (68), Expect = 0.27
Identities = 25/76 (32%), Positives = 29/76 (38%), Gaps = 11/76 (14%)
Query: 48 QCVEDSQCPLTRKCCY-RACFRQCVPRVSVKLGSCPEDQLR---CLSPMNHLCHKDSDCS 103
QC + C T CC R C C R S + SC Q C P CH S
Sbjct: 88 QCCQSMCCQPT--CCRPRCCISSCC-RPSCCVSSCCRPQCCQSVCCQPT--CCHPSCSIS 142
Query: 104 G--KKRCCHSACGRDC 117
+ CC S+C R C
Sbjct: 143 SCCRPSCCESSCCRPC 158
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 30.8 bits (68), Expect = 0.27
Identities = 18/71 (25%), Positives = 29/71 (40%), Gaps = 14/71 (19%)
Query: 47 DQCVEDSQCPLTRKCCYRACFRQCVPRVSVKLGS----CPEDQLRCLSPMNHLCHKDSDC 102
+QCV++++C C +C+ LGS CP + CH ++C
Sbjct: 2650 NQCVDENECSNPNACGSASCYNT--------LGSYKCACPSGF--SFDQFSSACHDVNEC 2699
Query: 103 SGKKRCCHSAC 113
S K C+ C
Sbjct: 2700 SSSKNPCNYGC 2710
>gi|13994129 keratin associated protein 4-12 [Homo sapiens]
Length = 201
Score = 30.8 bits (68), Expect = 0.27
Identities = 22/76 (28%), Positives = 26/76 (34%), Gaps = 6/76 (7%)
Query: 48 QCVEDSQCPLT---RKCCYRACFRQCVPRVSVKLGSCPEDQLRCLSPMNHLCHKDSDCSG 104
QC + C T CC C R R S + SC Q C + S C
Sbjct: 89 QCCQSVCCQPTCCRPSCCQTTCCRTTCCRPSCCVSSCCRPQCCQSVCCQPTCCRPSCCIS 148
Query: 105 KK---RCCHSACGRDC 117
CC S+C R C
Sbjct: 149 SSCCPSCCESSCCRPC 164
Score = 27.3 bits (59), Expect = 3.0
Identities = 20/71 (28%), Positives = 25/71 (35%), Gaps = 5/71 (7%)
Query: 48 QCVEDSQCPLT---RKCCYRACFRQCVPRVSVKLGSCPEDQLRCLSPMNHLCHKDSDCSG 104
QC + C T CC C R R S + SC Q C + S C
Sbjct: 49 QCCQSVCCQPTCCRPSCCQTTCCRTTCCRPSCCVSSCCRPQCCQSVCCQPTCCRPSCC-- 106
Query: 105 KKRCCHSACGR 115
+ CC + C R
Sbjct: 107 QTTCCRTTCCR 117
Score = 25.8 bits (55), Expect = 8.7
Identities = 16/55 (29%), Positives = 20/55 (36%), Gaps = 2/55 (3%)
Query: 61 CCYRACFRQCVPRVSVKLGSCPEDQLRCLSPMNHLCHKDSDCSGKKRCCHSACGR 115
CC C R R S + SC Q C + S C + CC + C R
Sbjct: 25 CCQTTCCRTTCCRPSCCVSSCCRPQCCQSVCCQPTCCRPSCC--QTTCCRTTCCR 77
>gi|21703706 WAP four-disulfide core domain 10A precursor [Homo
sapiens]
Length = 79
Score = 30.8 bits (68), Expect = 0.27
Identities = 10/24 (41%), Positives = 11/24 (45%)
Query: 94 HLCHKDSDCSGKKRCCHSACGRDC 117
HLC DC CC + CG C
Sbjct: 52 HLCESHRDCQANNICCSTYCGNVC 75
>gi|19743803 fibulin 5 precursor [Homo sapiens]
Length = 448
Score = 30.4 bits (67), Expect = 0.35
Identities = 23/94 (24%), Positives = 35/94 (37%), Gaps = 9/94 (9%)
Query: 34 CPPDDGPCLLSVPDQCVEDSQCPLTRKCCYRACFRQCVPRVSVKLGSCPE-----DQLRC 88
C D G L C + +C + C +CV + SCP D R
Sbjct: 230 CRCDPGYELEEDGVHCSDMDECSFSEFLCQH----ECVNQPGTYFCSCPPGYILLDDNRS 285
Query: 89 LSPMNHLCHKDSDCSGKKRCCHSACGRDCRDPAR 122
+N H++ C+ ++ C + G C DP R
Sbjct: 286 CQDINECEHRNHTCNLQQTCYNLQGGFKCIDPIR 319
>gi|239751308 PREDICTED: keratin associated protein 4-9 isoform 1
[Homo sapiens]
Length = 210
Score = 30.4 bits (67), Expect = 0.35
Identities = 22/71 (30%), Positives = 27/71 (38%), Gaps = 9/71 (12%)
Query: 48 QCVEDSQCPLT---RKCCYRACFRQCVPRVSVKLGSCPEDQLRCLSPM--NHLCHKDSDC 102
QC + C T CC C R R S + SC Q C P+ C + S C
Sbjct: 53 QCCQSVCCQPTCSRPSCCQTTCCRTTCYRPSCCVSSCCRPQ--CCQPVCCQPTCCRPSCC 110
Query: 103 SGKKRCCHSAC 113
+ CCH C
Sbjct: 111 --ETTCCHPRC 119
Score = 30.0 bits (66), Expect = 0.46
Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 11/75 (14%)
Query: 49 CVEDSQCPLTRKCCY-RACFRQCVPRVSVKLGSCPEDQLR---CLSPMNHLCHKDSDCSG 104
C S C T CC+ R C C R S + SC + Q C P + C S
Sbjct: 104 CCRPSCCETT--CCHPRCCISSCC-RPSCCVSSCCKPQCCQSVCCQP--NCCRPSCSISS 158
Query: 105 --KKRCCHSACGRDC 117
+ CC S+C R C
Sbjct: 159 CCRPSCCESSCCRPC 173
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.140 0.485
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,158,641
Number of Sequences: 37866
Number of extensions: 318268
Number of successful extensions: 1301
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 85
Number of HSP's that attempted gapping in prelim test: 1162
Number of HSP's gapped (non-prelim): 204
length of query: 123
length of database: 18,247,518
effective HSP length: 89
effective length of query: 34
effective length of database: 14,877,444
effective search space: 505833096
effective search space used: 505833096
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.