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Search of human proteins with 217035121
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|217035121 HMG-BOX transcription factor BBX isoform 1 [Homo
sapiens]
(941 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|217035121 HMG-BOX transcription factor BBX isoform 1 [Homo sa... 1902 0.0
gi|18378731 HMG-BOX transcription factor BBX isoform 2 [Homo sap... 1823 0.0
gi|112421108 capicua homolog [Homo sapiens] 110 6e-24
gi|13899269 SRY-box 7 [Homo sapiens] 62 3e-09
gi|194688135 high-mobility group box 2 [Homo sapiens] 61 4e-09
gi|194688133 high-mobility group box 2 [Homo sapiens] 61 4e-09
gi|11321591 high-mobility group box 2 [Homo sapiens] 61 4e-09
gi|4759162 SRY-box 14 [Homo sapiens] 61 4e-09
gi|11967991 SRY-box 17 [Homo sapiens] 61 6e-09
gi|8924248 SRY-box 18 [Homo sapiens] 60 1e-08
gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens] 59 2e-08
gi|5902108 SRY-box 21 [Homo sapiens] 59 2e-08
gi|28195386 sex-determining region Y-box 2 [Homo sapiens] 59 3e-08
gi|5902106 SRY-box 15 [Homo sapiens] 55 2e-07
gi|104526627 triadin [Homo sapiens] 55 3e-07
gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens] 55 4e-07
gi|4557853 transcription factor SOX9 [Homo sapiens] 54 5e-07
gi|41055989 M-phase phosphoprotein 8 [Homo sapiens] 54 7e-07
gi|21361411 HMG-box transcription factor 1 [Homo sapiens] 54 7e-07
gi|226371625 transcription factor 7-like 2 isoform 5 [Homo sapiens] 54 9e-07
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 53 1e-06
gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens] 52 2e-06
gi|170014696 transcription factor 7-like 2 isoform 2 [Homo sapiens] 52 3e-06
gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens] 52 3e-06
gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Hom... 52 3e-06
gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Hom... 52 3e-06
gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo... 52 3e-06
gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo... 52 3e-06
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 51 4e-06
gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo... 50 8e-06
>gi|217035121 HMG-BOX transcription factor BBX isoform 1 [Homo
sapiens]
Length = 941
Score = 1902 bits (4926), Expect = 0.0
Identities = 941/941 (100%), Positives = 941/941 (100%)
Query: 1 MKGSNRNKDHSAEGEGVGKRPKRKCLQWHPLLAKKLLDFSEEEEEEDEEEDIDKVQLLGA 60
MKGSNRNKDHSAEGEGVGKRPKRKCLQWHPLLAKKLLDFSEEEEEEDEEEDIDKVQLLGA
Sbjct: 1 MKGSNRNKDHSAEGEGVGKRPKRKCLQWHPLLAKKLLDFSEEEEEEDEEEDIDKVQLLGA 60
Query: 61 DGLEQDVGETEDDESPEQRARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAV 120
DGLEQDVGETEDDESPEQRARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAV
Sbjct: 61 DGLEQDVGETEDDESPEQRARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAV 120
Query: 121 LDPKEKQKYTDMAKEYKDAFMKANPGYKWCPTTNKPVKSPTPTVNPRKKLWAFPSDSSRD 180
LDPKEKQKYTDMAKEYKDAFMKANPGYKWCPTTNKPVKSPTPTVNPRKKLWAFPSDSSRD
Sbjct: 121 LDPKEKQKYTDMAKEYKDAFMKANPGYKWCPTTNKPVKSPTPTVNPRKKLWAFPSDSSRD 180
Query: 181 LPSPKKAKTEEMPQLNFGMADPTQMGGLSMLLLAGEHALGTPEVSSGTCRPDVSESPELR 240
LPSPKKAKTEEMPQLNFGMADPTQMGGLSMLLLAGEHALGTPEVSSGTCRPDVSESPELR
Sbjct: 181 LPSPKKAKTEEMPQLNFGMADPTQMGGLSMLLLAGEHALGTPEVSSGTCRPDVSESPELR 240
Query: 241 QKSPLFQFAEISSSTSHSDASTKQCQTSALFQFAEISSNTSQLGGAEPVKRCGKSALFQL 300
QKSPLFQFAEISSSTSHSDASTKQCQTSALFQFAEISSNTSQLGGAEPVKRCGKSALFQL
Sbjct: 241 QKSPLFQFAEISSSTSHSDASTKQCQTSALFQFAEISSNTSQLGGAEPVKRCGKSALFQL 300
Query: 301 AEMCLASEGMKMEESKLIKAKESDGGRIKELEKGKEEKEIKMEKTDETRLQKEAEFEKSA 360
AEMCLASEGMKMEESKLIKAKESDGGRIKELEKGKEEKEIKMEKTDETRLQKEAEFEKSA
Sbjct: 301 AEMCLASEGMKMEESKLIKAKESDGGRIKELEKGKEEKEIKMEKTDETRLQKEAEFEKSA 360
Query: 361 KENLRDSKELRNFEALQIDDIMAIKMEDPKEIRKEELEEDHKCSHFPDFSYSASSKIIIS 420
KENLRDSKELRNFEALQIDDIMAIKMEDPKEIRKEELEEDHKCSHFPDFSYSASSKIIIS
Sbjct: 361 KENLRDSKELRNFEALQIDDIMAIKMEDPKEIRKEELEEDHKCSHFPDFSYSASSKIIIS 420
Query: 421 DVPSRKDHMCHPHGIMIIEDPAALNKPEKLKKKKKKSKMDRHGNDKSTPKKTCKKRQSSE 480
DVPSRKDHMCHPHGIMIIEDPAALNKPEKLKKKKKKSKMDRHGNDKSTPKKTCKKRQSSE
Sbjct: 421 DVPSRKDHMCHPHGIMIIEDPAALNKPEKLKKKKKKSKMDRHGNDKSTPKKTCKKRQSSE 480
Query: 481 SDIESVIYTIEAVAKGDWGIEKLGDTPRKKVRTSSSGKGSILDAKPPKKKVKSREKKMSK 540
SDIESVIYTIEAVAKGDWGIEKLGDTPRKKVRTSSSGKGSILDAKPPKKKVKSREKKMSK
Sbjct: 481 SDIESVIYTIEAVAKGDWGIEKLGDTPRKKVRTSSSGKGSILDAKPPKKKVKSREKKMSK 540
Query: 541 EKSSDTTKESRPPDFISISASKNISGETPEGIKAEPLTPMEDALPPSLSGQAKPEDSDCH 600
EKSSDTTKESRPPDFISISASKNISGETPEGIKAEPLTPMEDALPPSLSGQAKPEDSDCH
Sbjct: 541 EKSSDTTKESRPPDFISISASKNISGETPEGIKAEPLTPMEDALPPSLSGQAKPEDSDCH 600
Query: 601 RKIETCGSRKSERSCKGALYKTLVSEGMLTSLRANVDRGKRSSGKGNSSDHEGCWNEESW 660
RKIETCGSRKSERSCKGALYKTLVSEGMLTSLRANVDRGKRSSGKGNSSDHEGCWNEESW
Sbjct: 601 RKIETCGSRKSERSCKGALYKTLVSEGMLTSLRANVDRGKRSSGKGNSSDHEGCWNEESW 660
Query: 661 TFSQSGTSGSKKFKKTKPKEDCLLGSAKLDEEFEKKFNSLPQYSPVTFDRKCVPVPRKKK 720
TFSQSGTSGSKKFKKTKPKEDCLLGSAKLDEEFEKKFNSLPQYSPVTFDRKCVPVPRKKK
Sbjct: 661 TFSQSGTSGSKKFKKTKPKEDCLLGSAKLDEEFEKKFNSLPQYSPVTFDRKCVPVPRKKK 720
Query: 721 KTGNVSSEPTKTSKGPFQSQKKNLFHKIVSKYKHKKEKPNVPEKGSGDKWSNKQLFLDAI 780
KTGNVSSEPTKTSKGPFQSQKKNLFHKIVSKYKHKKEKPNVPEKGSGDKWSNKQLFLDAI
Sbjct: 721 KTGNVSSEPTKTSKGPFQSQKKNLFHKIVSKYKHKKEKPNVPEKGSGDKWSNKQLFLDAI 780
Query: 781 HPTEAIFSEDRNTMEPVHKVKNIPSIFNTPEPTTTQEPLVGSQKRKARKTKITHLVRTAD 840
HPTEAIFSEDRNTMEPVHKVKNIPSIFNTPEPTTTQEPLVGSQKRKARKTKITHLVRTAD
Sbjct: 781 HPTEAIFSEDRNTMEPVHKVKNIPSIFNTPEPTTTQEPLVGSQKRKARKTKITHLVRTAD 840
Query: 841 GRVSPAGGTLDDKPKEQLQRSLPKATETDCNDKCSHNTEVGETRSSTPEMPAVSAFFSLA 900
GRVSPAGGTLDDKPKEQLQRSLPKATETDCNDKCSHNTEVGETRSSTPEMPAVSAFFSLA
Sbjct: 841 GRVSPAGGTLDDKPKEQLQRSLPKATETDCNDKCSHNTEVGETRSSTPEMPAVSAFFSLA 900
Query: 901 ALAEVAAMENVHRGQRSTPLTHDGQPKEMPQAPVLISCADQ 941
ALAEVAAMENVHRGQRSTPLTHDGQPKEMPQAPVLISCADQ
Sbjct: 901 ALAEVAAMENVHRGQRSTPLTHDGQPKEMPQAPVLISCADQ 941
>gi|18378731 HMG-BOX transcription factor BBX isoform 2 [Homo
sapiens]
Length = 911
Score = 1823 bits (4722), Expect = 0.0
Identities = 911/941 (96%), Positives = 911/941 (96%), Gaps = 30/941 (3%)
Query: 1 MKGSNRNKDHSAEGEGVGKRPKRKCLQWHPLLAKKLLDFSEEEEEEDEEEDIDKVQLLGA 60
MKGSNRNKDHSAEGEGVGKRPKRKCLQWHPLLAKKLLDFSEEEEEEDEEEDIDKVQLLGA
Sbjct: 1 MKGSNRNKDHSAEGEGVGKRPKRKCLQWHPLLAKKLLDFSEEEEEEDEEEDIDKVQLLGA 60
Query: 61 DGLEQDVGETEDDESPEQRARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAV 120
DGLEQDVGETEDDESPEQRARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAV
Sbjct: 61 DGLEQDVGETEDDESPEQRARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAV 120
Query: 121 LDPKEKQKYTDMAKEYKDAFMKANPGYKWCPTTNKPVKSPTPTVNPRKKLWAFPSDSSRD 180
LDPKEKQKYTDMAKEYKDAFMKANPGYKWCPTTNKPVKSPTPTVNPRKKLWAFPSDSSRD
Sbjct: 121 LDPKEKQKYTDMAKEYKDAFMKANPGYKWCPTTNKPVKSPTPTVNPRKKLWAFPSDSSRD 180
Query: 181 LPSPKKAKTEEMPQLNFGMADPTQMGGLSMLLLAGEHALGTPEVSSGTCRPDVSESPELR 240
LPSPKKAKTEEMPQLNFGMADPTQMGGLSMLLLAGEHALGTPEVSSGTCRPDVSESPELR
Sbjct: 181 LPSPKKAKTEEMPQLNFGMADPTQMGGLSMLLLAGEHALGTPEVSSGTCRPDVSESPELR 240
Query: 241 QKSPLFQFAEISSSTSHSDASTKQCQTSALFQFAEISSNTSQLGGAEPVKRCGKSALFQL 300
QKSPLFQFAEISSSTSHSDASTKQCQTSALFQFAEISSNTSQLGGAEPVKRCGKSALFQL
Sbjct: 241 QKSPLFQFAEISSSTSHSDASTKQCQTSALFQFAEISSNTSQLGGAEPVKRCGKSALFQL 300
Query: 301 AEMCLASEGMKMEESKLIKAKESDGGRIKELEKGKEEKEIKMEKTDETRLQKEAEFEKSA 360
AEMCLASEGMKMEESKLIKAKESDGGRIKELEKGKEEKEIKMEKTDETRLQKEAEFEKSA
Sbjct: 301 AEMCLASEGMKMEESKLIKAKESDGGRIKELEKGKEEKEIKMEKTDETRLQKEAEFEKSA 360
Query: 361 KENLRDSKELRNFEALQIDDIMAIKMEDPKEIRKEELEEDHKCSHFPDFSYSASSKIIIS 420
KENLRDSKELRNFEALQIDDIMAIKMEDPKEIRKEELEEDHKCSHFPDFSYSASSKIIIS
Sbjct: 361 KENLRDSKELRNFEALQIDDIMAIKMEDPKEIRKEELEEDHKCSHFPDFSYSASSKIIIS 420
Query: 421 DVPSRKDHMCHPHGIMIIEDPAALNKPEKLKKKKKKSKMDRHGNDKSTPKKTCKKRQSSE 480
DVPSRKDHMCHPHGIMIIEDPAALNKPEKLKKKKKKSKMDRHGNDKSTPKKTCKKRQSSE
Sbjct: 421 DVPSRKDHMCHPHGIMIIEDPAALNKPEKLKKKKKKSKMDRHGNDKSTPKKTCKKRQSSE 480
Query: 481 SDIESVIYTIEAVAKGDWGIEKLGDTPRKKVRTSSSGKGSILDAKPPKKKVKSREKKMSK 540
SDIESVIYTIEAVAKGDWGIEKLGDTPRKKVRTSSSGKGSILDAKPPKKKVKSREKKMSK
Sbjct: 481 SDIESVIYTIEAVAKGDWGIEKLGDTPRKKVRTSSSGKGSILDAKPPKKKVKSREKKMSK 540
Query: 541 EKSSDTTKESRPPDFISISASKNISGETPEGIKAEPLTPMEDALPPSLSGQAKPEDSDCH 600
EKSSDTTKESRPPDFISISASKNISGETPEGIKAEPLTPMEDALPPSLSGQAKPEDSDCH
Sbjct: 541 EKSSDTTKESRPPDFISISASKNISGETPEGIKAEPLTPMEDALPPSLSGQAKPEDSDCH 600
Query: 601 RKIETCGSRKSERSCKGALYKTLVSEGMLTSLRANVDRGKRSSGKGNSSDHEGCWNEESW 660
RKIETCGSRKSERSCKGALYKTLVSEGMLTSLRANVDRGKRSSGKGNSSDHEGCWNEESW
Sbjct: 601 RKIETCGSRKSERSCKGALYKTLVSEGMLTSLRANVDRGKRSSGKGNSSDHEGCWNEESW 660
Query: 661 TFSQSGTSGSKKFKKTKPKEDCLLGSAKLDEEFEKKFNSLPQYSPVTFDRKCVPVPRKKK 720
TFSQSGTSGSKKFKKTKPKEDCLLGSAKLDEEFEKKFNSLPQYSPVTFDRKCVPVPRKKK
Sbjct: 661 TFSQSGTSGSKKFKKTKPKEDCLLGSAKLDEEFEKKFNSLPQYSPVTFDRKCVPVPRKKK 720
Query: 721 KTGNVSSEPTKTSKGPFQSQKKNLFHKIVSKYKHKKEKPNVPEKGSGDKWSNKQLFLDAI 780
KTGNVSSEPTKTS KGSGDKWSNKQLFLDAI
Sbjct: 721 KTGNVSSEPTKTS------------------------------KGSGDKWSNKQLFLDAI 750
Query: 781 HPTEAIFSEDRNTMEPVHKVKNIPSIFNTPEPTTTQEPLVGSQKRKARKTKITHLVRTAD 840
HPTEAIFSEDRNTMEPVHKVKNIPSIFNTPEPTTTQEPLVGSQKRKARKTKITHLVRTAD
Sbjct: 751 HPTEAIFSEDRNTMEPVHKVKNIPSIFNTPEPTTTQEPLVGSQKRKARKTKITHLVRTAD 810
Query: 841 GRVSPAGGTLDDKPKEQLQRSLPKATETDCNDKCSHNTEVGETRSSTPEMPAVSAFFSLA 900
GRVSPAGGTLDDKPKEQLQRSLPKATETDCNDKCSHNTEVGETRSSTPEMPAVSAFFSLA
Sbjct: 811 GRVSPAGGTLDDKPKEQLQRSLPKATETDCNDKCSHNTEVGETRSSTPEMPAVSAFFSLA 870
Query: 901 ALAEVAAMENVHRGQRSTPLTHDGQPKEMPQAPVLISCADQ 941
ALAEVAAMENVHRGQRSTPLTHDGQPKEMPQAPVLISCADQ
Sbjct: 871 ALAEVAAMENVHRGQRSTPLTHDGQPKEMPQAPVLISCADQ 911
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 110 bits (275), Expect = 6e-24
Identities = 56/117 (47%), Positives = 71/117 (60%), Gaps = 7/117 (5%)
Query: 54 KVQLLGADGLEQDVGETEDDESPEQRA----RRPMNAFLLFCKRHRSLVRQEHPRLDNRG 109
+ Q L A E+D +D SP +R RRPMNAF++F KRHR+LV Q HP DNR
Sbjct: 170 RTQSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRT 229
Query: 110 ATKILADWWAVLDPKEKQKYTDMAKEYKDAFMKANPGYKWCPTTNKPVKSPTPTVNP 166
+KIL +WW L PKEKQKY D+A + K+A KA+P +KWC NK K + P
Sbjct: 230 VSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWC---NKDRKKSSSEAKP 283
>gi|13899269 SRY-box 7 [Homo sapiens]
Length = 388
Score = 61.6 bits (148), Expect = 3e-09
Identities = 32/94 (34%), Positives = 48/94 (51%)
Query: 73 DESPEQRARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDM 132
D+ E R RRPMNAF+++ K R + ++P L N +K+L W L +K+ Y D
Sbjct: 38 DKGSESRIRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDE 97
Query: 133 AKEYKDAFMKANPGYKWCPTTNKPVKSPTPTVNP 166
A+ + M+ P YK+ P K K V+P
Sbjct: 98 AERLRLQHMQDYPNYKYRPRRKKQAKRLCKRVDP 131
>gi|194688135 high-mobility group box 2 [Homo sapiens]
Length = 209
Score = 61.2 bits (147), Expect = 4e-09
Identities = 39/148 (26%), Positives = 66/148 (44%), Gaps = 7/148 (4%)
Query: 23 RKCLQ-WHPLLAKKLLDFSEEEEEEDEEEDIDKVQLLGADGLEQDVGETEDDESPEQRAR 81
+KC + W + AK+ F + + + D + + G ++ G+ +D +P +
Sbjct: 43 KKCSERWKTMSAKEKSKFEDMAKSDKARYDREMKNYVPPKGDKK--GKKKDPNAP----K 96
Query: 82 RPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKEYKDAFM 141
RP +AF LFC HR ++ EHP L K L + W+ K+KQ Y A + K+ +
Sbjct: 97 RPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYE 156
Query: 142 KANPGYKWCPTTNKPVKSPTPTVNPRKK 169
K Y+ + K P +KK
Sbjct: 157 KDIAAYRAKGKSEAGKKGPGRPTGSKKK 184
Score = 34.3 bits (77), Expect = 0.56
Identities = 33/122 (27%), Positives = 52/122 (42%), Gaps = 8/122 (6%)
Query: 79 RARRPMNAFLLFCKRHRSLVRQEHPRLDNRGA--TKILADWWAVLDPKEKQKYTDMAKEY 136
+ R M+++ F + R +++HP A +K ++ W + KEK K+ DMAK
Sbjct: 8 KPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDMAKSD 67
Query: 137 KDAFMKANPGYKWCPTTNKPVKSPTPTVNPRKKLWAFPSDSSRDLPSPKKAKTEEMPQLN 196
K + + Y P +K K P P++ AF S P K E P L+
Sbjct: 68 KARYDREMKNYV-PPKGDKKGKKKDPNA-PKRPPSAFFLFCSEHRPKIK----SEHPGLS 121
Query: 197 FG 198
G
Sbjct: 122 IG 123
>gi|194688133 high-mobility group box 2 [Homo sapiens]
Length = 209
Score = 61.2 bits (147), Expect = 4e-09
Identities = 39/148 (26%), Positives = 66/148 (44%), Gaps = 7/148 (4%)
Query: 23 RKCLQ-WHPLLAKKLLDFSEEEEEEDEEEDIDKVQLLGADGLEQDVGETEDDESPEQRAR 81
+KC + W + AK+ F + + + D + + G ++ G+ +D +P +
Sbjct: 43 KKCSERWKTMSAKEKSKFEDMAKSDKARYDREMKNYVPPKGDKK--GKKKDPNAP----K 96
Query: 82 RPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKEYKDAFM 141
RP +AF LFC HR ++ EHP L K L + W+ K+KQ Y A + K+ +
Sbjct: 97 RPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYE 156
Query: 142 KANPGYKWCPTTNKPVKSPTPTVNPRKK 169
K Y+ + K P +KK
Sbjct: 157 KDIAAYRAKGKSEAGKKGPGRPTGSKKK 184
Score = 34.3 bits (77), Expect = 0.56
Identities = 33/122 (27%), Positives = 52/122 (42%), Gaps = 8/122 (6%)
Query: 79 RARRPMNAFLLFCKRHRSLVRQEHPRLDNRGA--TKILADWWAVLDPKEKQKYTDMAKEY 136
+ R M+++ F + R +++HP A +K ++ W + KEK K+ DMAK
Sbjct: 8 KPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDMAKSD 67
Query: 137 KDAFMKANPGYKWCPTTNKPVKSPTPTVNPRKKLWAFPSDSSRDLPSPKKAKTEEMPQLN 196
K + + Y P +K K P P++ AF S P K E P L+
Sbjct: 68 KARYDREMKNYV-PPKGDKKGKKKDPNA-PKRPPSAFFLFCSEHRPKIK----SEHPGLS 121
Query: 197 FG 198
G
Sbjct: 122 IG 123
>gi|11321591 high-mobility group box 2 [Homo sapiens]
Length = 209
Score = 61.2 bits (147), Expect = 4e-09
Identities = 39/148 (26%), Positives = 66/148 (44%), Gaps = 7/148 (4%)
Query: 23 RKCLQ-WHPLLAKKLLDFSEEEEEEDEEEDIDKVQLLGADGLEQDVGETEDDESPEQRAR 81
+KC + W + AK+ F + + + D + + G ++ G+ +D +P +
Sbjct: 43 KKCSERWKTMSAKEKSKFEDMAKSDKARYDREMKNYVPPKGDKK--GKKKDPNAP----K 96
Query: 82 RPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKEYKDAFM 141
RP +AF LFC HR ++ EHP L K L + W+ K+KQ Y A + K+ +
Sbjct: 97 RPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGEMWSEQSAKDKQPYEQKAAKLKEKYE 156
Query: 142 KANPGYKWCPTTNKPVKSPTPTVNPRKK 169
K Y+ + K P +KK
Sbjct: 157 KDIAAYRAKGKSEAGKKGPGRPTGSKKK 184
Score = 34.3 bits (77), Expect = 0.56
Identities = 33/122 (27%), Positives = 52/122 (42%), Gaps = 8/122 (6%)
Query: 79 RARRPMNAFLLFCKRHRSLVRQEHPRLDNRGA--TKILADWWAVLDPKEKQKYTDMAKEY 136
+ R M+++ F + R +++HP A +K ++ W + KEK K+ DMAK
Sbjct: 8 KPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDMAKSD 67
Query: 137 KDAFMKANPGYKWCPTTNKPVKSPTPTVNPRKKLWAFPSDSSRDLPSPKKAKTEEMPQLN 196
K + + Y P +K K P P++ AF S P K E P L+
Sbjct: 68 KARYDREMKNYV-PPKGDKKGKKKDPNA-PKRPPSAFFLFCSEHRPKIK----SEHPGLS 121
Query: 197 FG 198
G
Sbjct: 122 IG 123
>gi|4759162 SRY-box 14 [Homo sapiens]
Length = 240
Score = 61.2 bits (147), Expect = 4e-09
Identities = 51/160 (31%), Positives = 73/160 (45%), Gaps = 16/160 (10%)
Query: 76 PEQRARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKE 135
P +RPMNAF+++ + R + QE+P++ N +K L W +L EK+ Y D AK
Sbjct: 4 PSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKR 63
Query: 136 YKDAFMKANPGYKWCPTTNKPVK--------SPTPTVNPRKKLWA--FPSDSSRDLPS-P 184
+ MK +P YK+ P KP P P + L A P +S L S P
Sbjct: 64 LRAQHMKEHPDYKYRP-RRKPKNLLKKDRYVFPLPYLGDTDPLKAAGLPVGASDGLLSAP 122
Query: 185 KKAKTEEMP-QLNFGMADPTQMGGLSMLLLAGE--HALGT 221
+KA+ P + + DP Q S + GE H L T
Sbjct: 123 EKARAFLPPASAPYSLLDPAQFSS-SAIQKMGEVPHTLAT 161
>gi|11967991 SRY-box 17 [Homo sapiens]
Length = 414
Score = 60.8 bits (146), Expect = 6e-09
Identities = 30/82 (36%), Positives = 46/82 (56%)
Query: 77 EQRARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKEY 136
E R RRPMNAF+++ K R + Q++P L N +K+L W L EK+ + + A+
Sbjct: 65 ESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFVEEAERL 124
Query: 137 KDAFMKANPGYKWCPTTNKPVK 158
+ M+ +P YK+ P K VK
Sbjct: 125 RVQHMQDHPNYKYRPRRRKQVK 146
>gi|8924248 SRY-box 18 [Homo sapiens]
Length = 384
Score = 60.1 bits (144), Expect = 1e-08
Identities = 29/91 (31%), Positives = 49/91 (53%)
Query: 68 GETEDDESPEQRARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQ 127
G E + E R RRPMNAF+++ K R + Q++P L N +K+L W L+ EK+
Sbjct: 73 GRGERQAADESRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGKAWKELNAAEKR 132
Query: 128 KYTDMAKEYKDAFMKANPGYKWCPTTNKPVK 158
+ + A+ + ++ +P YK+ P K +
Sbjct: 133 PFVEEAERLRVQHLRDHPNYKYRPRRKKQAR 163
>gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]
Length = 391
Score = 59.3 bits (142), Expect = 2e-08
Identities = 27/75 (36%), Positives = 44/75 (58%)
Query: 77 EQRARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKEY 136
+ R +RPMNAF+++ + R + QE+P++ N +K L W V+ EK+ + D AK
Sbjct: 48 QDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRL 107
Query: 137 KDAFMKANPGYKWCP 151
+ MK +P YK+ P
Sbjct: 108 RALHMKEHPDYKYRP 122
>gi|5902108 SRY-box 21 [Homo sapiens]
Length = 276
Score = 59.3 bits (142), Expect = 2e-08
Identities = 32/99 (32%), Positives = 50/99 (50%), Gaps = 7/99 (7%)
Query: 76 PEQRARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKE 135
P +RPMNAF+++ + R + QE+P++ N +K L W +L EK+ + D AK
Sbjct: 4 PVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKR 63
Query: 136 YKDAFMKANPGYKWCPTTNKPVKSPTPTVNPRKKLWAFP 174
+ MK +P YK+ P P +K +AFP
Sbjct: 64 LRAMHMKEHPDYKYRPRRK-------PKTLLKKDKFAFP 95
>gi|28195386 sex-determining region Y-box 2 [Homo sapiens]
Length = 317
Score = 58.5 bits (140), Expect = 3e-08
Identities = 29/77 (37%), Positives = 46/77 (59%), Gaps = 1/77 (1%)
Query: 75 SPEQRARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAK 134
SP+ R +RPMNAF+++ + R + QE+P++ N +K L W +L EK+ + D AK
Sbjct: 37 SPD-RVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAK 95
Query: 135 EYKDAFMKANPGYKWCP 151
+ MK +P YK+ P
Sbjct: 96 RLRALHMKEHPDYKYRP 112
>gi|5902106 SRY-box 15 [Homo sapiens]
Length = 233
Score = 55.5 bits (132), Expect = 2e-07
Identities = 24/76 (31%), Positives = 44/76 (57%)
Query: 76 PEQRARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKE 135
P ++ +RPMNAF+++ R + Q++P++ N +K L W +LD EK+ + + AK
Sbjct: 45 PLEKVKRPMNAFMVWSSAQRRQMAQQNPKMHNSEISKRLGAQWKLLDEDEKRPFVEEAKR 104
Query: 136 YKDAFMKANPGYKWCP 151
+ ++ P YK+ P
Sbjct: 105 LRARHLRDYPDYKYRP 120
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 55.1 bits (131), Expect = 3e-07
Identities = 128/546 (23%), Positives = 200/546 (36%), Gaps = 72/546 (13%)
Query: 40 SEEEEEEDEEEDIDKVQLLGADGLEQDV--GETEDDESPEQRARRPMNAFLLFCKRHRSL 97
SE+EE++D +ED DK ++ ++++ +TE E PE++ + + H+
Sbjct: 116 SEDEEDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVT--------HKEK 167
Query: 98 VRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKEYKDAFMKANPGYKWCPTTNKPV 157
+ + ++ + + A ++ KEK + +AKE K KA K T K V
Sbjct: 168 EKGKE-KVREKEKPEKKATHKEKIEKKEKPETKTLAKEQK----KAKTAEKSEEKTKKEV 222
Query: 158 K-----SPTPTVNPRKKLWAFPSDSSRDLPSPKKA--KTEEMPQLNF--GMADPTQMGGL 208
K T K++ PS K A K E+ Q F M D G L
Sbjct: 223 KGGKQEKVKQTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDL 282
Query: 209 SMLLLAGEHALGTPEVSSGTCRPDVSESPELRQKSPLFQFAEISSSTSHSDASTKQCQTS 268
G+ P + + SP L +K + AE TS + K+
Sbjct: 283 K----PGQSPAIPPPLPTEQASRPTPASPALEEKEGEKKKAE-KKVTSETKKKEKEDIKK 337
Query: 269 ALFQFAEISSNTSQLGGAEPVKRCGKSALFQLAEMCLASEGMKMEESKLIKAKESDGGRI 328
+ I + G A K+ ++A A + K E+SK K
Sbjct: 338 KSEKETAIDVEKKEPGKASETKQ----GTVKIAAQAAAKKDEKKEDSKKTKKPAE----- 388
Query: 329 KELEKGK--EEKEIKMEKTDETRLQKEAEFEKSAKENLRDSKELRNFEALQIDDIMAIKM 386
E KGK E+KE +E + + +K K +KE A+ I + K
Sbjct: 389 VEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKE--EIGAVSIKKAVPGKK 446
Query: 387 ED------PKEIRKEELEEDHKCSHFPDFSYSASSKIIIS----DVPSRKDHMCHPHGIM 436
E+ +EIRKE+ + + K+ S + ++KD G
Sbjct: 447 EEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKMSKAGKE 506
Query: 437 IIEDPAAL-----NKPEKLKKKKKK----SKMDRHGNDKSTPKKTCKKRQSSESDIESV- 486
+ P L KPE KK+ K K+ H D P+KT + E ++ V
Sbjct: 507 VKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKVLKQVK 566
Query: 487 IYTIEAVAKGDWGIEKLGDTPRKKVRTSSSGKGSILDAKP-PKKKVKSREKKMSKEKSSD 545
TIE AK P KK SI KP P K S + K+K+
Sbjct: 567 AVTIEKTAK---------PKPTKKAEHREREPPSIKTDKPKPTPKGTSEVTESGKKKTEI 617
Query: 546 TTKESR 551
+ KES+
Sbjct: 618 SEKESK 623
Score = 40.4 bits (93), Expect = 0.008
Identities = 111/586 (18%), Positives = 218/586 (37%), Gaps = 65/586 (11%)
Query: 34 KKLLDFSEEEEEEDEEEDIDKVQLLGADGLEQDVGETEDDESPEQRARRPMNAFLLFCKR 93
+K+ + + E++ +E I+K + L ++ + + E E++ ++ + +
Sbjct: 172 EKVREKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVK 231
Query: 94 HRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKEYKDAFMKAN--PGYKWC- 150
+ +E + ++ K + AV ++K +Y + D F+ + PG
Sbjct: 232 QTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYA-FCRYMIDIFVHGDLKPGQSPAI 290
Query: 151 --PTTNKPVKSPTPTVNPRKKLWAFPSDSSRDLPSPKKAKTEE-------------MPQL 195
P + PTP ++ + + + S K K +E + +
Sbjct: 291 PPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKK 350
Query: 196 NFGMADPTQMGGLSMLLLAGEHALGTPEVSSGTCRPDVSESPELRQKSPLFQFAEISSST 255
G A T+ G + + A E S T +P E P+ +++ + E + S
Sbjct: 351 EPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSP 410
Query: 256 SHSDASTKQCQTSALFQFAEISSNTSQLGGAEPVKRCGKSALFQLAEMCLASEGMKMEES 315
+ Q A + A+ + A P K+ K+ ++ ++ E
Sbjct: 411 KKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKT-----------TKTVEQEIR 459
Query: 316 KLIKAKESDGGRIKELEKGKEEKEIKMEKTDETRLQKEAEFEKSAKE------NLRDSKE 369
K K S + KE KGKEEK K E +K+ + K+ KE L+ KE
Sbjct: 460 KEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKE 519
Query: 370 LRNFEALQIDDIMAIKMEDPKEIRKEELEEDHKCSHFPDFSYSASSKIIISDVPSRKDHM 429
+ ++ + AI + +I K+++ + K S+ + ++ V +
Sbjct: 520 EKPEPQIKKEAKPAI--SEKVQIHKQDIVKPEK-----TVSHGKPEEKVLKQVKA----- 567
Query: 430 CHPHGIMIIEDPAALNKPEKLKKKKKKSKMDRHGNDKSTPKKTCKKRQSSESDIESVIYT 489
+ IE A +K + ++++ + K TPK T + +S + E I
Sbjct: 568 ------VTIEKTAKPKPTKKAEHREREPPSIKTDKPKPTPKGTSEVTESGKKKTE--ISE 619
Query: 490 IEAVAKGDWGIEKLGDTPRKKVRTSSSGKGSILDAKPPKKKVKSREKKMSKEKSSDTTKE 549
E+ K D K + R S ++ A+ P + K E + +K+ + T++
Sbjct: 620 KESKEKADM---KHLREEKVSTRKESLQLHNVTKAEKPARVSKDVEDVPASKKAKEGTED 676
Query: 550 SRP---PDFISISASKNISGETPEGIKAEPLTPMEDALPPSLSGQA 592
P IS + G G + P TP + P SGQA
Sbjct: 677 VSPTKQKSPISFFQCVYLDGYNGYGFQF-PFTPAD--RPGESSGQA 719
Score = 34.3 bits (77), Expect = 0.56
Identities = 81/368 (22%), Positives = 132/368 (35%), Gaps = 61/368 (16%)
Query: 446 KPE-KLKKK---KKKSKMDRHGNDKSTPKKTCKKRQSSESDIESVIYTIEAVAKGDWGIE 501
KPE K++ K K+K K +K P+K ++ E + T+ K E
Sbjct: 153 KPERKIQTKVTHKEKEKGKEKVREKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAE 212
Query: 502 KLGDTPRKKVRTSSSGKGSILDAK-------PPKKKVKSREKKMSKEKSSDTTKESRPPD 554
K + +K+V+ K AK P K K K ++K + K + +
Sbjct: 213 KSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRY 272
Query: 555 FISISASKNIS-GETPEGIKAEPLTPMEDALPPSLSGQAKPEDSDCHRKIETCGSRKSER 613
I I ++ G++P P P E A P+ + A E +K E + ++++
Sbjct: 273 MIDIFVHGDLKPGQSP---AIPPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKK 329
Query: 614 SCKGALYKTLVSEGMLTSLRANVDRGKRSSGKGNSSDHEGCWNEESWTFSQSGTSGSKK- 672
K + K E +D K+ GK + + + T + + +KK
Sbjct: 330 KEKEDIKKKSEKE-------TAIDVEKKEPGKASET--------KQGTVKIAAQAAAKKD 374
Query: 673 -----FKKTKPKEDCLLGSAKLDEEFE---------KKFNSLPQYSPVTFD--------- 709
KKTK + K E+ E KK +S+P V
Sbjct: 375 EKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIG 434
Query: 710 ----RKCVPVPRKKKKTGNVSSEPTKTSKGPFQSQKKNLFHKIVSKYKHKKEKPNVPEKG 765
+K VP +++K T V E K G S K+ K K K +K ++ EK
Sbjct: 435 AVSIKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSILKD---KEPIKGKEEKVPASLKEKE 491
Query: 766 SGDKWSNK 773
K K
Sbjct: 492 PETKKDEK 499
>gi|30061556 SRY (sex determining region Y)-box 3 [Homo sapiens]
Length = 446
Score = 54.7 bits (130), Expect = 4e-07
Identities = 26/75 (34%), Positives = 42/75 (56%)
Query: 77 EQRARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKEY 136
+ R +RPMNAF+++ + R + E+P++ N +K L W +L EK+ + D AK
Sbjct: 136 QDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFIDEAKRL 195
Query: 137 KDAFMKANPGYKWCP 151
+ MK P YK+ P
Sbjct: 196 RAVHMKEYPDYKYRP 210
>gi|4557853 transcription factor SOX9 [Homo sapiens]
Length = 509
Score = 54.3 bits (129), Expect = 5e-07
Identities = 25/79 (31%), Positives = 44/79 (55%)
Query: 81 RRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKEYKDAF 140
+RPMNAF+++ + R + ++P L N +K L W +L+ EK+ + + A+ +
Sbjct: 106 KRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQH 165
Query: 141 MKANPGYKWCPTTNKPVKS 159
K +P YK+ P K VK+
Sbjct: 166 KKDHPDYKYQPRRRKSVKN 184
>gi|41055989 M-phase phosphoprotein 8 [Homo sapiens]
Length = 860
Score = 53.9 bits (128), Expect = 7e-07
Identities = 58/264 (21%), Positives = 109/264 (41%), Gaps = 53/264 (20%)
Query: 318 IKAKESDGGRIKELEKGKEEK-------EIKMEKTDETRLQKEAEFEKSAKENLRDSKEL 370
+K K++ G++K+ K E +++ +K ++ E +K K+ ++++KEL
Sbjct: 168 LKKKKAKAGKLKDKSKPDLESSLESLVFDLRTKKRISEAKEELKESKKPKKDEVKETKEL 227
Query: 371 RNFEALQIDDIMAIKMEDPKEIRKEELEEDHKCSHFPDFSYSASSKIIISDVPSRKDHMC 430
+ + +I D+ EDPKE RK + E+ + S S +++D P +D
Sbjct: 228 KKVKKGEIRDLKTKTREDPKENRKTKKEKFVE-------SQVESESSVLNDSPFPED--- 277
Query: 431 HPHGIMIIEDPAALNKPEKLKKKKKKSKMDRHGNDKSTP---KKTCKKRQSSESDIESVI 487
D L+ + +K+ KS +R G D +K S+E D +
Sbjct: 278 ---------DSEGLHSDSREEKQNTKSARERAGQDMGLEHGFEKPLDSAMSAEEDTD--- 325
Query: 488 YTIEAVAKGDWGIEKLGDTPRKKVRTSSSGKGSILDAKPPKKKVKSREKKMSKEKSSDTT 547
+G + TPRK T + K +A KK V +++ + KS+
Sbjct: 326 ------VRG----RRKKKTPRKAEDTRENRKLENKNAFLEKKTVPKKQRNQDRSKSAAEL 375
Query: 548 KESRPPDFISISASKNISGETPEG 571
++ P +S +TP+G
Sbjct: 376 EKLMP-----------VSAQTPKG 388
Score = 38.1 bits (87), Expect = 0.039
Identities = 28/119 (23%), Positives = 51/119 (42%), Gaps = 7/119 (5%)
Query: 439 EDPAALNKPEKLKKKKKKSKMDRHGNDKSTPKKTCKKRQSSESDIESVIYTIEAVAKGDW 498
ED + K +KL+++++KS D K K + ES +ES+++ + +
Sbjct: 146 EDTSPKKKKKKLRQREEKSPDDLKKKKAKAGKLKDKSKPDLESSLESLVFDLRTKKRISE 205
Query: 499 GIEKLGDTPRKK-------VRTSSSGKGSILDAKPPKKKVKSREKKMSKEKSSDTTKES 550
E+L ++ + K KG I D K ++ +K KEK ++ ES
Sbjct: 206 AKEELKESKKPKKDEVKETKELKKVKKGEIRDLKTKTREDPKENRKTKKEKFVESQVES 264
>gi|21361411 HMG-box transcription factor 1 [Homo sapiens]
Length = 514
Score = 53.9 bits (128), Expect = 7e-07
Identities = 26/67 (38%), Positives = 39/67 (58%)
Query: 79 RARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKEYKD 138
+ +RPMNAF+LF K++R Q +P DNR + IL D W + +E++ YT AK +
Sbjct: 433 KCKRPMNAFMLFAKKYRVEYTQMYPGKDNRAISVILGDRWKKMKNEERRMYTLEAKALAE 492
Query: 139 AFMKANP 145
+ NP
Sbjct: 493 EQKRLNP 499
>gi|226371625 transcription factor 7-like 2 isoform 5 [Homo sapiens]
Length = 579
Score = 53.5 bits (127), Expect = 9e-07
Identities = 46/201 (22%), Positives = 84/201 (41%), Gaps = 16/201 (7%)
Query: 44 EEEDEEEDIDKVQLLGADGLEQDVGETEDDESPEQRARRPMNAFLLFCKRHRSLVRQEHP 103
++E + D+ + QD + E+ + P ++P+NAF+L+ K R+ V E
Sbjct: 297 KQESSQSDVGSLH----SSKHQDSKKEEEKKKPH--IKKPLNAFMLYMKEMRAKVVAECT 350
Query: 104 RLDNRGATKILADWWAVLDPKEKQKYTDMAKEYKDAFMKANPGYKWCPTTNKPVKSPTPT 163
++ +IL W L +E+ KY ++A++ + M+ PG W N K
Sbjct: 351 LKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPG--WSARDNYGKKK---- 404
Query: 164 VNPRKKLWAFPSDSSRDLPSPKKAKTEEMPQLNFGMADPTQMGGLSMLLLAGEHALGTPE 223
++K P +++ DL +PKK + P + + + GE + +P
Sbjct: 405 ---KRKRDKQPGETN-DLSAPKKCRARFGLDQQNNWCGPCRRKKKCVRYIQGEGSCLSPP 460
Query: 224 VSSGTCRPDVSESPELRQKSP 244
S G+ SP L P
Sbjct: 461 SSDGSLLDSPPPSPNLLGSPP 481
Score = 37.0 bits (84), Expect = 0.087
Identities = 45/185 (24%), Positives = 66/185 (35%), Gaps = 46/185 (24%)
Query: 451 KKKKKKSKMDRHGNDKSTPKKTCKKRQSSESDIESVIYTIEAVAKGDWGIEKLGDTPRKK 510
KKK+K+ K ND S PKK C+ R + + +W G RKK
Sbjct: 403 KKKRKRDKQPGETNDLSAPKK-CRARFGLDQ-------------QNNW----CGPCRRKK 444
Query: 511 --VR---------TSSSGKGSILDAKPPKKKVKSREKKMSKEKSSDTTKES--------- 550
VR + S GS+LD+ PP + + +K ++ T S
Sbjct: 445 KCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLGSPPRDAKSQTEQTQPLSLSLKPDPLA 504
Query: 551 ------RPPDFISISASKNISGETPEGIKAEPLTPMEDALPPSLSGQAKPEDSDCHRKIE 604
PP + A+ S P G P ++ A P S A+P S H
Sbjct: 505 HLSMMPPPPALLLAEATHKASALCPNGALDLPPAALQPAAPS--SSIAQPSTSSLHSHSS 562
Query: 605 TCGSR 609
G++
Sbjct: 563 LAGTQ 567
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 53.1 bits (126), Expect = 1e-06
Identities = 113/572 (19%), Positives = 195/572 (34%), Gaps = 55/572 (9%)
Query: 313 EESKLIKAKESDGGRIKELEKGKEEKEIKMEKTDETRLQKEAEFEKSAKENLRDSKELRN 372
+E+K + KE +GG +E E G+EE + E E E + KE + E ++
Sbjct: 476 KEAKEEEGKEEEGGEEEEAEGGEEETK---SPPAEEAASPEKEAKSPVKEEAKSPAEAKS 532
Query: 373 FEALQIDDIMAIKM-EDPKEIRKEELEEDHKCSHFPDFSYSASSKIIISDVPSRKDHMCH 431
E + +K E K KEE + P + S + S +
Sbjct: 533 PEKEEAKSPAEVKSPEKAKSPAKEEAKS-------PPEAKSPEKEEAKSPAEVKSPEKAK 585
Query: 432 PHGIMIIEDPAALNKPEKLKKKKKKSKMDRHGNDKSTPKKTCKKRQSSESDIESVIYTIE 491
+ PA PE K KS + + K K+ S ++++S
Sbjct: 586 SPAKEEAKSPAEAKSPE-----KAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKS 640
Query: 492 AVAKGDWGIEKLGDTPRKKVRTSSSGKGSI-LDAKPPKK---KVKSREKKMSKEKSSDTT 547
+ EK +++ ++ K + +AK P+K VK+ K K K S
Sbjct: 641 PTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAK-SPVK 699
Query: 548 KESRPPDFISISASKNISG--ETPEGIKAEPLTPMEDALPPSLSGQAKPEDSDCHRKIET 605
+E++ P+ + + +K E TP E A P PE + K +T
Sbjct: 700 EEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTP-EKAKSPVKEEAKSPEKAKSPEKAKT 758
Query: 606 CGSRKSERSCKGALYKTLVSEGMLTSLRANVDRGKRSSGKGNSSDHEGCWNEESWTFSQS 665
+ E ++ ++ V +S K S E
Sbjct: 759 LDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKE------------- 805
Query: 666 GTSGSKKFKKTKPKEDCLLGSAKLDEE-FEKKFNSLPQYSPVTFDRKCVPVPR-KKKKTG 723
+K +K PK++ + K +E+ E K P+ + + K P+ ++KK
Sbjct: 806 ---DAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAE---EEKAPATPKTEEKKDS 859
Query: 724 NVSSEPTKTSKGPFQSQKKNLFHKIVSKYKHKKEKPNVPEKGSGDKWSNKQLFLDAIHPT 783
P K + P +KK + K K+ K ++ + DK K + P
Sbjct: 860 KKEEAPKKEAPKPKVEEKKE-----PAVEKPKESKVEAKKEEAEDK--KKVPTPEKEAPA 912
Query: 784 EAIFSEDRNTMEPVHKVKNIPSIFNTPEPTTTQEPLVGSQKR---KARKTKITHLVRTAD 840
+ ED E K P EP+ E + ++ K K K +
Sbjct: 913 KVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTE 972
Query: 841 GRVSPAGGTLDDKPKEQLQRSLPKATETDCND 872
+ TL +P + K++ TD D
Sbjct: 973 AKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKD 1004
Score = 51.6 bits (122), Expect = 3e-06
Identities = 121/564 (21%), Positives = 215/564 (38%), Gaps = 70/564 (12%)
Query: 38 DFSEEEEEEDEEEDIDKVQLLGADGLEQDVGETEDDESPEQRARRPMNAFLLFCKRHRSL 97
+ +EEEE+E +EE+ G E++ GE E+ E E+ + P ++
Sbjct: 469 EVTEEEEKEAKEEE----------GKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKS 518
Query: 98 VRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKEYKDAFMKANPGYKWCPTTNKPV 157
+E + + + + + K +K AKE + +A K + V
Sbjct: 519 PVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEV 578
Query: 158 KSPTPTVNPRKKLWAFPSDSSRDLPSPKKAKT--EEMPQLNFGMADPTQMGGLSMLLLAG 215
KSP +P K+ P+++ SP+KAK+ +E + P + S +
Sbjct: 579 KSPEKAKSPAKEEAKSPAEAK----SPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKS 634
Query: 216 EHALGTPEVSSGTCRPDVSESPELRQ-------KSPLFQFA---EISSSTSHSDASTKQC 265
+P P+ ++SPE + KSP+ A E + S ++A + +
Sbjct: 635 PEKAKSPTKEEAKS-PEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEK 693
Query: 266 QTSALFQFAEISSNTSQLGGAEPVKRCGKSALFQLAEMCLASEGMKMEESKL-IKAKESD 324
S + + A+ PVK KS + A+ + E E++K +K +
Sbjct: 694 AKSPVKEEAKSPEKAKS-----PVKEEAKSP--EKAKSPVKEEAKTPEKAKSPVKEEAKS 746
Query: 325 GGRIKELEKGK----EEKEIKMEKTDETRLQKEAEFEKSAKENLRDSKELRNFEALQIDD 380
+ K EK K + E K +E R + EK+ + K ++ +D
Sbjct: 747 PEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKED 806
Query: 381 IMAIKMEDPKE------IRKEELEEDHKCSHFPDFSYSASSKIIISDVPSRKDHMCHPHG 434
A + E PK+ +++EE ++ K P + + +KD
Sbjct: 807 AKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPAT-PKTEEKKDSKKEEAP 865
Query: 435 IMIIEDPAALNKPEKLKKKKKKSKMD---RHGNDKS---TPKKTCKKRQSSESDIESVIY 488
P K E +K K+SK++ DK TP+K + + D +
Sbjct: 866 KKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEK 925
Query: 489 TIEAVAKGDWGIEKLGDTPRKKVRTSSSGKGSILD-AKPPKKKVKSR------EKKMSKE 541
T A + D K P +K + K + + AK P++K K+ +K +SKE
Sbjct: 926 TEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKE 985
Query: 542 ----------KSSDTT-KESRPPD 554
KSS T K+S+PP+
Sbjct: 986 PSKPKAEKAEKSSSTDQKDSKPPE 1009
>gi|30179903 SRY (sex determining region Y)-box 8 [Homo sapiens]
Length = 446
Score = 52.4 bits (124), Expect = 2e-06
Identities = 24/79 (30%), Positives = 42/79 (53%)
Query: 81 RRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKEYKDAF 140
+RPMNAF+++ + R + ++P L N +K L W +L EK+ + + A+ +
Sbjct: 103 KRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQH 162
Query: 141 MKANPGYKWCPTTNKPVKS 159
K +P YK+ P K K+
Sbjct: 163 KKDHPDYKYQPRRRKSAKA 181
>gi|170014696 transcription factor 7-like 2 isoform 2 [Homo sapiens]
Length = 596
Score = 52.0 bits (123), Expect = 3e-06
Identities = 50/211 (23%), Positives = 85/211 (40%), Gaps = 19/211 (9%)
Query: 44 EEEDEEEDIDKVQLLGADGLEQDVGETEDDESPEQRARRPMNAFLLFCKRHRSLVRQEHP 103
++E + D+ + QD + E+ + P ++P+NAF+L+ K R+ V E
Sbjct: 297 KQESSQSDVGSLH----SSKHQDSKKEEEKKKPH--IKKPLNAFMLYMKEMRAKVVAECT 350
Query: 104 RLDNRGATKILADWWAVLDPKEKQKYTDMAKEYKDAFMKANPGYKWCPTTN-------KP 156
++ +IL W L +E+ KY ++A++ + M+ PG W N K
Sbjct: 351 LKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPG--WSARDNYGKKKKRKR 408
Query: 157 VKSPTPTVNPRKKLWAFPSDS---SRDLPSPKKAKTEEMPQLNFGMADPTQMGGLSMLLL 213
K P T N + + P S DL +PKK + P + + +
Sbjct: 409 DKQPGET-NEHSECFLNPCLSLPPITDLSAPKKCRARFGLDQQNNWCGPCRRKKKCVRYI 467
Query: 214 AGEHALGTPEVSSGTCRPDVSESPELRQKSP 244
GE + +P S G+ SP L P
Sbjct: 468 QGEGSCLSPPSSDGSLLDSPPPSPNLLGSPP 498
>gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens]
Length = 466
Score = 52.0 bits (123), Expect = 3e-06
Identities = 30/129 (23%), Positives = 59/129 (45%), Gaps = 11/129 (8%)
Query: 42 EEEEEDEEEDIDKVQLLGADGLEQDVG-----------ETEDDESPEQRARRPMNAFLLF 90
++E++D E D DK + + + Q + + +RPMNAF+++
Sbjct: 55 KKEQQDGEADDDKFPVCIREAVSQVLSGYDWTLVPMPVRVNGASKSKPHVKRPMNAFMVW 114
Query: 91 CKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKEYKDAFMKANPGYKWC 150
+ R + ++P L N +K L W +L+ +K+ + + A+ + K +P YK+
Sbjct: 115 AQAARRKLADQYPHLHNAELSKTLGKLWRLLNESDKRPFIEEAERLRMQHKKDHPDYKYQ 174
Query: 151 PTTNKPVKS 159
P K K+
Sbjct: 175 PRRRKNGKA 183
>gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Homo
sapiens]
Length = 841
Score = 51.6 bits (122), Expect = 3e-06
Identities = 25/77 (32%), Positives = 38/77 (49%)
Query: 75 SPEQRARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAK 134
S E +RPMNAF+++ K R + Q P + N +KIL W + +EKQ Y +
Sbjct: 629 SSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQA 688
Query: 135 EYKDAFMKANPGYKWCP 151
++ P YK+ P
Sbjct: 689 RLSKIHLEKYPNYKYKP 705
>gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Homo
sapiens]
Length = 801
Score = 51.6 bits (122), Expect = 3e-06
Identities = 25/77 (32%), Positives = 38/77 (49%)
Query: 75 SPEQRARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAK 134
S E +RPMNAF+++ K R + Q P + N +KIL W + +EKQ Y +
Sbjct: 589 SSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQA 648
Query: 135 EYKDAFMKANPGYKWCP 151
++ P YK+ P
Sbjct: 649 RLSKIHLEKYPNYKYKP 665
>gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo
sapiens]
Length = 804
Score = 51.6 bits (122), Expect = 3e-06
Identities = 25/77 (32%), Positives = 38/77 (49%)
Query: 75 SPEQRARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAK 134
S E +RPMNAF+++ K R + Q P + N +KIL W + +EKQ Y +
Sbjct: 592 SSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQA 651
Query: 135 EYKDAFMKANPGYKWCP 151
++ P YK+ P
Sbjct: 652 RLSKIHLEKYPNYKYKP 668
>gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo
sapiens]
Length = 808
Score = 51.6 bits (122), Expect = 3e-06
Identities = 25/77 (32%), Positives = 38/77 (49%)
Query: 75 SPEQRARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAK 134
S E +RPMNAF+++ K R + Q P + N +KIL W + +EKQ Y +
Sbjct: 596 SSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQA 655
Query: 135 EYKDAFMKANPGYKWCP 151
++ P YK+ P
Sbjct: 656 RLSKIHLEKYPNYKYKP 672
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 51.2 bits (121), Expect = 4e-06
Identities = 76/393 (19%), Positives = 151/393 (38%), Gaps = 45/393 (11%)
Query: 313 EESKLIKAKESDGGRIKELEKGKEEKEIKMEKTDETRLQKEAEFEKSAKENLRDSKEL-- 370
EE K I SD + +E E+ K+E E+KME +ET +++ + + S E + D E+
Sbjct: 337 EEEKEIAIVHSDAEKEQEEEEQKQEMEVKME--EETEVRESEKQQDSQPEEVMDVLEMVE 394
Query: 371 ---------RNFEALQIDDIMAIKMEDPKEIRKE---ELEEDHKCSHFPDFSYSASSKII 418
E +++ + + E KE+ E E+E D +C + S+ +
Sbjct: 395 NVKHVIADQEVMETNRVESVEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDM 454
Query: 419 ISDVPSRKDHMCHPHGIMIIEDPAALNKPEKLKKKKKKSKMDRHGNDKSTPKKTCKKRQS 478
+ +++ P +PE + + + +S+ +S P +
Sbjct: 455 EKESEEKEEKESEP-------------QPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQ 501
Query: 479 SESDIESVIY-TIEAVAKGDWGIEKLGDTPRKKVRTSSSGKGSILDAKP-PKKKVKSREK 536
E +V+ T + + + + D P + V+ + +L P K K K+R +
Sbjct: 502 PEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSR 561
Query: 537 KMSKEKSSDTTKESRPPDFISISASKNISGETPEGIKAEPLTPMEDALPPSLSGQAKPED 596
+ ++ + SR S S+S S + + S SG + +
Sbjct: 562 SRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDS 621
Query: 597 SDCHRKIETCGSRKSERSCKGALY----KTLVSEGMLTSLRANVDRGKRSSGKGNSSDHE 652
S T S +S +G + K S + ++R +SS G+S D +
Sbjct: 622 SS-----STSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTK 676
Query: 653 GCWNEES-----WTFSQSGTSGSKKFKKTKPKE 680
G ++ S + S+S SG + + + ++
Sbjct: 677 GSKDKNSRSDRKRSISESSRSGKRSSRSERDRK 709
>gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo
sapiens]
Length = 377
Score = 50.4 bits (119), Expect = 8e-06
Identities = 26/83 (31%), Positives = 39/83 (46%)
Query: 69 ETEDDESPEQRARRPMNAFLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQK 128
E+ S E +RPMNAF+++ K R + Q P + N +KIL W + EKQ
Sbjct: 159 ESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEKQP 218
Query: 129 YTDMAKEYKDAFMKANPGYKWCP 151
Y + ++ P YK+ P
Sbjct: 219 YYEEQARLSKQHLEKYPDYKYKP 241
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.126 0.362
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,416,471
Number of Sequences: 37866
Number of extensions: 2087561
Number of successful extensions: 16422
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 213
Number of HSP's successfully gapped in prelim test: 519
Number of HSP's that attempted gapping in prelim test: 12206
Number of HSP's gapped (non-prelim): 4105
length of query: 941
length of database: 18,247,518
effective HSP length: 112
effective length of query: 829
effective length of database: 14,006,526
effective search space: 11611410054
effective search space used: 11611410054
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.