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Search of human proteins with 21536464
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21536464 palmitoylated membrane protein 3 [Homo sapiens]
(585 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21536464 palmitoylated membrane protein 3 [Homo sapiens] 1172 0.0
gi|111154074 palmitoylated membrane protein 7 [Homo sapiens] 628 e-180
gi|14780902 membrane protein, palmitoylated 4 [Homo sapiens] 410 e-114
gi|38570142 membrane protein, palmitoylated 5 [Homo sapiens] 357 1e-98
gi|21361598 membrane protein, palmitoylated 6 [Homo sapiens] 304 2e-82
gi|186700629 calcium/calmodulin-dependent serine protein kinase ... 303 4e-82
gi|186700627 calcium/calmodulin-dependent serine protein kinase ... 300 2e-81
gi|52630447 palmitoylated membrane protein 2 [Homo sapiens] 296 3e-80
gi|186972120 calcium/calmodulin-dependent serine protein kinase ... 292 7e-79
gi|4505237 palmitoylated membrane protein 1 [Homo sapiens] 256 5e-68
gi|218156340 chapsyn-110 isoform 3 [Homo sapiens] 183 4e-46
gi|218156338 chapsyn-110 isoform 1 [Homo sapiens] 182 1e-45
gi|91199538 chapsyn-110 isoform 2 [Homo sapiens] 182 1e-45
gi|119943106 synapse-associated protein 102 isoform a [Homo sapi... 181 1e-45
gi|119943108 synapse-associated protein 102 isoform b [Homo sapi... 180 3e-45
gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens] 167 2e-41
gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens] 167 2e-41
gi|218156270 chapsyn-110 isoform 4 [Homo sapiens] 165 9e-41
gi|4557529 post-synaptic density protein 95 isoform 1 [Homo sapi... 147 3e-35
gi|192447426 post-synaptic density protein 95 isoform 2 [Homo sa... 147 3e-35
gi|226874833 guanylate kinase 1 isoform b [Homo sapiens] 108 2e-23
gi|226874831 guanylate kinase 1 isoform a [Homo sapiens] 108 2e-23
gi|4504221 guanylate kinase 1 isoform b [Homo sapiens] 108 2e-23
gi|21389483 leucine-rich repeats and guanylate kinase domain con... 65 1e-10
gi|95089461 discs large homolog 5 [Homo sapiens] 61 2e-09
gi|82659097 par-6 partitioning defective 6 homolog alpha isoform... 56 1e-07
gi|8394417 par-6 partitioning defective 6 homolog alpha isoform ... 56 1e-07
gi|62955042 PAR-6 beta [Homo sapiens] 55 1e-07
gi|14210518 PAR-6 gamma protein [Homo sapiens] 53 7e-07
gi|223890252 glutamate receptor interacting protein 1 [Homo sapi... 52 2e-06
>gi|21536464 palmitoylated membrane protein 3 [Homo sapiens]
Length = 585
Score = 1172 bits (3032), Expect = 0.0
Identities = 585/585 (100%), Positives = 585/585 (100%)
Query: 1 MPVLSEDSGLHETLALLTSQLRPDSNHKEEMGFLRDVFSEKSLSYLMKIHEKLRYYERQS 60
MPVLSEDSGLHETLALLTSQLRPDSNHKEEMGFLRDVFSEKSLSYLMKIHEKLRYYERQS
Sbjct: 1 MPVLSEDSGLHETLALLTSQLRPDSNHKEEMGFLRDVFSEKSLSYLMKIHEKLRYYERQS 60
Query: 61 PTPVLHSAVALAEDVMEELQAASVHSDERELLQLLSTPHLRAVLMVHDTVAQKNFDPVLP 120
PTPVLHSAVALAEDVMEELQAASVHSDERELLQLLSTPHLRAVLMVHDTVAQKNFDPVLP
Sbjct: 61 PTPVLHSAVALAEDVMEELQAASVHSDERELLQLLSTPHLRAVLMVHDTVAQKNFDPVLP 120
Query: 121 PLPDNIDEDFDEESVKIVRLVKNKEPLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVG 180
PLPDNIDEDFDEESVKIVRLVKNKEPLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVG
Sbjct: 121 PLPDNIDEDFDEESVKIVRLVKNKEPLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVG 180
Query: 181 DELREVNGIAVLHKRPDEISQILAQSQGSITLKIIPATQEEDRLKESKVFMRALFHYNPR 240
DELREVNGIAVLHKRPDEISQILAQSQGSITLKIIPATQEEDRLKESKVFMRALFHYNPR
Sbjct: 181 DELREVNGIAVLHKRPDEISQILAQSQGSITLKIIPATQEEDRLKESKVFMRALFHYNPR 240
Query: 241 EDRAIPCQEAGLPFQRRQVLEVVSQDDPTWWQAKRVGDTNLRAGLIPSKGFQERRLSYRR 300
EDRAIPCQEAGLPFQRRQVLEVVSQDDPTWWQAKRVGDTNLRAGLIPSKGFQERRLSYRR
Sbjct: 241 EDRAIPCQEAGLPFQRRQVLEVVSQDDPTWWQAKRVGDTNLRAGLIPSKGFQERRLSYRR 300
Query: 301 AAGTLPSPQSLRKPPYDQPCDKETCDCEGYLKGHYVAGLRRSFRLGCRERLGGSQEGKMS 360
AAGTLPSPQSLRKPPYDQPCDKETCDCEGYLKGHYVAGLRRSFRLGCRERLGGSQEGKMS
Sbjct: 301 AAGTLPSPQSLRKPPYDQPCDKETCDCEGYLKGHYVAGLRRSFRLGCRERLGGSQEGKMS 360
Query: 361 SGAESPELLTYEEVARYQHQPGERPRLVVLIGSLGARLHELKQKVVAENPQHFGVAVPHT 420
SGAESPELLTYEEVARYQHQPGERPRLVVLIGSLGARLHELKQKVVAENPQHFGVAVPHT
Sbjct: 361 SGAESPELLTYEEVARYQHQPGERPRLVVLIGSLGARLHELKQKVVAENPQHFGVAVPHT 420
Query: 421 TRPRKSHEKEGVEYHFVSKQAFEADLHHNKFLEHGEYKENLYGTSLEAIQAVMAKNKVCL 480
TRPRKSHEKEGVEYHFVSKQAFEADLHHNKFLEHGEYKENLYGTSLEAIQAVMAKNKVCL
Sbjct: 421 TRPRKSHEKEGVEYHFVSKQAFEADLHHNKFLEHGEYKENLYGTSLEAIQAVMAKNKVCL 480
Query: 481 VDVEPEALKQLRTSEFKPYIIFVKPAIQEKRKTPPMSPACEDTAAPFDEQQQEMAASAAF 540
VDVEPEALKQLRTSEFKPYIIFVKPAIQEKRKTPPMSPACEDTAAPFDEQQQEMAASAAF
Sbjct: 481 VDVEPEALKQLRTSEFKPYIIFVKPAIQEKRKTPPMSPACEDTAAPFDEQQQEMAASAAF 540
Query: 541 IDRHYGHLVDAVLVKEDLQGAYSQLKVVLEKLSKDTHWVPVSWVR 585
IDRHYGHLVDAVLVKEDLQGAYSQLKVVLEKLSKDTHWVPVSWVR
Sbjct: 541 IDRHYGHLVDAVLVKEDLQGAYSQLKVVLEKLSKDTHWVPVSWVR 585
>gi|111154074 palmitoylated membrane protein 7 [Homo sapiens]
Length = 576
Score = 628 bits (1620), Expect = e-180
Identities = 322/597 (53%), Positives = 434/597 (72%), Gaps = 36/597 (6%)
Query: 1 MPVLS----EDSGLHETLALLTSQLRPDSNHKEEMGFLRDVFSEKSLSYLMKIHEKLRYY 56
MP LS D+GL+E LA L +QL+P + +E++ FL D+F EKSL L+KIHEKL YY
Sbjct: 1 MPALSTGSGSDTGLYELLAALPAQLQPHVDSQEDLTFLWDMFGEKSLHSLVKIHEKLHYY 60
Query: 57 ERQSPTPVLHSAVALAEDVMEELQAASVHSDERELLQLLSTPHLRAVLMVHDTVAQKNFD 116
E+QSP P+LH A ALA+D+ EELQ ++S+ RELL+LLS P+++A+L VHDTVAQKN+D
Sbjct: 61 EKQSPVPILHGAAALADDLAEELQNKPLNSEIRELLKLLSKPNVKALLSVHDTVAQKNYD 120
Query: 117 PVLPPLPDNIDEDFDEESVKIVRLVKNKEPLGATIRRDEHSGAVVVARIMRGGAADRSGL 176
PVLPP+P++ID++ E+SVKI+RLVKN+EPLGATI++DE +GA++VARIMRGGAADRSGL
Sbjct: 121 PVLPPMPEDIDDE--EDSVKIIRLVKNREPLGATIKKDEQTGAIIVARIMRGGAADRSGL 178
Query: 177 VHVGDELREVNGIAVLHKRPDEISQILAQSQGSITLKIIPATQEEDRLKESKVFMRALFH 236
+HVGDELREVNGI V KRP+EI QILAQSQG+IT KIIP ++EE KE K+F++ALF
Sbjct: 179 IHVGDELREVNGIPVEDKRPEEIIQILAQSQGAITFKIIPGSKEETPSKEGKMFIKALFD 238
Query: 237 YNPREDRAIPCQEAGLPFQRRQVLEVVSQDDPTWWQAKRVGDTNLRAGLIPSKGFQERRL 296
YNP ED+AIPC+EAGL F++ +L+++SQDD TWWQAK D N RAGLIPSK FQERRL
Sbjct: 239 YNPNEDKAIPCKEAGLSFKKGDILQIMSQDDATWWQAKHEADANPRAGLIPSKHFQERRL 298
Query: 297 SYRRAAGTLPSPQSLRKPPYDQPCDKETCDCEGYLKGHYVAGLRRSFRLGCRERLGGSQ- 355
+ RR P+ L +P + +G R+SFRL +++
Sbjct: 299 ALRR-------PEILVQPL--------------KVSNRKSSGFRKSFRLSRKDKKTNKSM 337
Query: 356 -EGKMSSGAESPELLTYEEVARYQHQPGERPRLVVLIGSLGARLHELKQKVVAENPQHFG 414
E K S ++ ++ TYEEV Y+ Q E+ RLVVL+G +G L+ELK+K++ + QH+G
Sbjct: 338 YECKKSDQYDTADVPTYEEVTPYRRQTNEKYRLVVLVGPVGVGLNELKRKLLISDTQHYG 397
Query: 415 VAVPHTTRPRKSHEKEGVEYHFVSKQAFEADLHHNKFLEHGEYKENLYGTSLEAIQAVMA 474
V VPHTTR R+S E +GVEY F+SK FE D+ +NKF+E+GEYK N YGTS++++++V+A
Sbjct: 398 VTVPHTTRARRSQESDGVEYIFISKHLFETDVQNNKFIEYGEYKNNYYGTSIDSVRSVLA 457
Query: 475 KNKVCLVDVEPEALKQLRTSEFKPYIIFVKP----AIQEKRKTPPMSPACED--TAAPFD 528
KNKVCL+DV+P +K LRT EFKPY+IF+KP ++E RK + + +D A PF
Sbjct: 458 KNKVCLLDVQPHTVKHLRTLEFKPYVIFIKPPSIERLRETRKNAKIISSRDDQGAAKPFT 517
Query: 529 EQQ-QEMAASAAFIDRHYGHLVDAVLVKEDLQGAYSQLKVVLEKLSKDTHWVPVSWV 584
E+ QEM SA ++ YGHL D +++ +DL A+++LK +KL +THWVPVSW+
Sbjct: 518 EEDFQEMIKSAQIMESQYGHLFDKIIINDDLTVAFNELKTTFDKLETETHWVPVSWL 574
>gi|14780902 membrane protein, palmitoylated 4 [Homo sapiens]
Length = 637
Score = 410 bits (1054), Expect = e-114
Identities = 233/613 (38%), Positives = 364/613 (59%), Gaps = 44/613 (7%)
Query: 8 SGLHETLALLTSQLRPD-SNHKEEMGFLRDVFSEKSLSYLMKIHEKLRYYERQSPTPVLH 66
+GL + L L+ +L S + L D+ L L+KI++ L+ ++ + P
Sbjct: 26 NGLSQILRLVLQELSLFYSRDVNGVCLLYDLLHSPWLQALLKIYDCLQEFKEKKLVPATP 85
Query: 67 SAVALAEDVMEELQAASVHSDERELLQLLSTPHLRAVLMVHDTVAQKNFDPVLPPLPDNI 126
A L+ +V+E L+ + +EL Q+L PH +A+L HDT+AQK+F+P+LPPLPDNI
Sbjct: 86 HAQVLSYEVVELLRETPTSPEIQELRQMLQAPHFKALLSAHDTIAQKDFEPLLPPLPDNI 145
Query: 127 DEDFDEESVKIVRLVKNKEPLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREV 186
E EE+++IV LVKN++PLGATI+R E +G ++VARI+ GG A+RSGL++ GD+L EV
Sbjct: 146 PES--EEAMRIVCLVKNQQPLGATIKRHEMTGDILVARIIHGGLAERSGLLYAGDKLVEV 203
Query: 187 NGIAVLHKRPDEISQILAQSQGSITLKIIPATQEEDRLKESKVFMRALFHYNPREDRAIP 246
NG++V P+++ ILA S+G+I K++P + + V++RA+ Y P+ED IP
Sbjct: 204 NGVSVEGLDPEQVIHILAMSRGTIMFKVVPVSDPPVN-SQQMVYVRAMTEYWPQEDPDIP 262
Query: 247 CQEAGLPFQRRQVLEVVSQDDPTWWQAKRVGDTNLRAGLIPSKGFQERRLS--------- 297
C +AGLPFQ+ +L++V Q+D WWQA+++ D AGL+PS +R+
Sbjct: 263 CMDAGLPFQKGDILQIVDQNDALWWQARKISDPATCAGLVPSNHLLKRKQREFWWSQPYQ 322
Query: 298 -YRRAAGTLP-SPQSLRKPPYDQPC---DKETCDCE----------GYLKGHYVAGLRRS 342
+ TL S + D+ C D+ET + E GY + ++AG RRS
Sbjct: 323 PHTCLKSTLSISMEEEDDMKIDEKCVEADEETFESEELSEDKEEFVGYGQKFFIAGFRRS 382
Query: 343 FRLGCRERLGGSQ-------EGKMSSGAESPELLTYEEVARYQHQPGERPRLVVLIGSLG 395
RL CR + S G S +P YEEV RYQ +P ++ RL+VL+G G
Sbjct: 383 MRL-CRRKSHLSPLHASVCCTGSCYSAVGAP----YEEVVRYQRRPSDKYRLIVLMGPSG 437
Query: 396 ARLHELKQKVVAENPQHFGVAVPHTTRPRKSHEKEGVEYHFVSKQAFEADLHHNKFLEHG 455
++EL+++++ NP HF AVPHTTR +KS+E G EYH+VSK+ FE ++ ++ LE+G
Sbjct: 438 VGVNELRRQLIEFNPSHFQSAVPHTTRTKKSYEMNGREYHYVSKETFENLIYSHRMLEYG 497
Query: 456 EYKENLYGTSLEAIQAVMAKNKVCLVDVEPEALKQLRTSEFKPYIIFVKPA----IQEKR 511
EYK +LYGTS++A+Q V+ + K+C++D+EP+ ++ +RT E KPY+IF+KP+ +++ R
Sbjct: 498 EYKGHLYGTSVDAVQTVLVEGKICVMDLEPQDIQGVRTHELKPYVIFIKPSNMRCMKQSR 557
Query: 512 KTPPMSPACEDTAAPFDEQQQEMAASAAFIDRHYGHLVDAVLVKEDLQGAYSQLKVVLEK 571
K + DE QEM A ++ +G D V+V + L A +QL ++K
Sbjct: 558 KNAKVITDYYVDMKFKDEDLQEMENLAQRMETQFGQFFDHVIVNDSLHDACAQLLSAIQK 617
Query: 572 LSKDTHWVPVSWV 584
++ WVP +W+
Sbjct: 618 AQEEPQWVPATWI 630
>gi|38570142 membrane protein, palmitoylated 5 [Homo sapiens]
Length = 675
Score = 357 bits (917), Expect = 1e-98
Identities = 205/577 (35%), Positives = 337/577 (58%), Gaps = 56/577 (9%)
Query: 24 DSNHKEEMGFLRDVFSEKSLSYLMKIHEKLRYYERQS--PTPVLHSAVALAEDVMEELQA 81
DS +E++ L + K KIH + + ++ P P++ +A LA++V L+
Sbjct: 140 DSQSQEDISLLLQLVQNKDFQNAFKIHNAITVHMNKASPPFPLISNAQDLAQEVQTVLKP 199
Query: 82 ASVHSDERELLQLLSTPHLRAVLMVHDTVAQKNFDPVLPPLPDN-IDEDFDE---ESVKI 137
H + +EL LL+TPH++A+L+ HD VA++ L P+ D + E + E+VKI
Sbjct: 200 VH-HKEGQELTALLNTPHIQALLLAHDKVAEQEMQ--LEPITDERVYESIGQYGGETVKI 256
Query: 138 VRLVKNKE-PLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIAVLHKRP 196
VR+ K ++ PLGAT+R + S V+++RI++GGAA++SGL+H GDE+ E+NGI + K
Sbjct: 257 VRIEKARDIPLGATVRNEMDS--VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDV 314
Query: 197 DEISQILAQSQGSITLKIIPATQ-EEDRLKESKVFMRALFHYNPREDRAIPCQEAGLPFQ 255
+E+ +L+ G++T +IP+ Q + KE+ + ++A F Y+P +D +PC+E GL FQ
Sbjct: 315 NEVFDLLSDMHGTLTFVLIPSQQIKPPPAKETVIHVKAHFDYDPSDDPYVPCRELGLSFQ 374
Query: 256 RRQVLEVVSQDDPTWWQAKRVGDTNLR--AGLIPSKGFQERRLSYRRAAGTLPSPQSLRK 313
+ +L V+SQ+DP WWQA R GD + + AGL+P K FQ++R + + Q++ +
Sbjct: 375 KGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGKSFQQQREAMK---------QTIEE 425
Query: 314 PPYDQPCDKETCDCEGYLKGHYVAGLRRSFRLGC-----RERLGGSQEGKMSSGAESPEL 368
DKE +S +L C ++R + ++ E+
Sbjct: 426 -------DKEP---------------EKSGKLWCAKKNKKKRKKVLYNANKNDDYDNEEI 463
Query: 369 LTYEEVARYQHQPGERPRLVVLIGSLGARLHELKQKVVAENPQHFGVAVPHTTRPRKSHE 428
LTYEE++ Y HQP R R ++LIG +EL+Q+++ + F AVPHTTR R+ E
Sbjct: 464 LTYEEMSLY-HQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQE 522
Query: 429 KEGVEYHFVSKQAFEADLHHNKFLEHGEYKENLYGTSLEAIQAVMAKNKVCLVDVEPEAL 488
G +YHFVS+QAFEAD+ KF+EHGE+++NLYGTS+++++ V+ K+CL+ + ++L
Sbjct: 523 VAGRDYHFVSRQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSL 582
Query: 489 KQLRTSEFKPYIIFVKPAIQEKRKTPPMSPACEDTAAPFDEQQQEMAASAAFIDRHYGHL 548
K LR S+ KPYIIF+ P QE+ + + ++ P E+ +E+ ++++ GH
Sbjct: 583 KTLRNSDLKPYIIFIAPPSQERLR----ALLAKEGKNPKPEELREIIEKTREMEQNNGHY 638
Query: 549 VDAVLVKEDLQGAYSQLKVVLEKLSKDTHWVPVSWVR 585
D +V DL AY +L ++ KL + WVP +W+R
Sbjct: 639 FDTAIVNSDLDKAYQELLRLINKLDTEPQWVPSTWLR 675
>gi|21361598 membrane protein, palmitoylated 6 [Homo sapiens]
Length = 540
Score = 304 bits (778), Expect = 2e-82
Identities = 193/575 (33%), Positives = 299/575 (52%), Gaps = 60/575 (10%)
Query: 23 PDSNHKEEMG--FLRDVFSEKSLSYLMKIHEKLRYYERQSPTPVLHSAVALAEDVMEELQ 80
P S EE+ FL+ + + L K HE+L E V + + L +++E++
Sbjct: 12 PSSTGAEEIDLIFLKGIMENPIVKSLAKAHERL---EDSKLEAVSDNNLELVNEILEDIT 68
Query: 81 AA-SVHSDERELLQLLSTPHLRAVLMVHDTVAQKNFDPVLPPLPDNIDEDFDEE-----S 134
+V + EL+ +L PH +++L HD VA K +D P P+ + + + +
Sbjct: 69 PLINVDENVAELVGILKEPHFQSLLEAHDIVASKCYDSP-PSSPEMNNSSINNQLLPVDA 127
Query: 135 VKIVRLVKNK-EPLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIAVLH 193
++I+ + K EPLG T R + + +V+ARI+ GG DR GL+HVGD ++EVNG V
Sbjct: 128 IRILGIHKRAGEPLGVTFRVENND--LVIARILHGGMIDRQGLLHVGDIIKEVNGHEV-G 184
Query: 194 KRPDEISQILAQSQGSITLKIIPATQEEDRLKESKVFMRALFHYNPREDRAIPCQEAGLP 253
P E+ ++L GS+TLKI+P+ + D + +VF++ F YNP D IPC+EAGL
Sbjct: 185 NNPKELQELLKNISGSVTLKILPSYR--DTITPQQVFVKCHFDYNPYNDNLIPCKEAGLK 242
Query: 254 FQRRQVLEVVSQDDPTWWQAKRVGDTNLRAGLIPSKGFQERRLSYRRAAGTLPSPQSLRK 313
F + ++L++V+++DP WWQA V + AGLIPS+ +E+R ++ R P
Sbjct: 243 FSKGEILQIVNREDPNWWQASHVKEGG-SAGLIPSQFLEEKRKAFVRRDWDNSGPFC--- 298
Query: 314 PPYDQPCDKETCDCEGYLKGHYVAGLRRSFRLGCRERLGGSQEGKMSSGAESPELLTYEE 373
T + K Y+ F + E+ YEE
Sbjct: 299 ---------GTISSKKKKKMMYLTTRNAEF--------------------DRHEIQIYEE 329
Query: 374 VARYQHQPGERPRLVVLIGSLGARLHELKQKVVAENPQHFGVAVPHTTRPRKSHEKEGVE 433
VA+ P + + +VLIG+ G LK + + NP FG VP T+R + EK+G
Sbjct: 330 VAK---MPPFQRKTLVLIGAQGVGRRSLKNRFIVLNPTRFGTTVPFTSRKPREDEKDGQA 386
Query: 434 YHFVSKQAFEADLHHNKFLEHGEYKENLYGTSLEAIQAVMAKNKVCLVDVEPEALKQLRT 493
Y FVS+ EAD+ K+LEHGEY+ NLYGT +++I V+ + C++DV P+ALK LRT
Sbjct: 387 YKFVSRSEMEADIKAGKYLEHGEYEGNLYGTKIDSILEVVQTGRTCILDVNPQALKVLRT 446
Query: 494 SEFKPYIIFVKPAIQEKRKTPPMSPACED----TAAPFDEQQQEMAASAAFIDRHYGHLV 549
SEF PY++F+ A E M A D T D ++ +A I R Y H
Sbjct: 447 SEFMPYVVFI--AAPELETLRAMHKAVVDAGITTKLLTDSDLKKTVDESARIQRAYNHYF 504
Query: 550 DAVLVKEDLQGAYSQLKVVLEKLSKDTHWVPVSWV 584
D +++ ++L A+ +L+ +EKL + WVP+SWV
Sbjct: 505 DLIIINDNLDKAFEKLQTAIEKLRMEPQWVPISWV 539
>gi|186700629 calcium/calmodulin-dependent serine protein kinase
isoform 3 [Homo sapiens]
Length = 897
Score = 303 bits (775), Expect = 4e-82
Identities = 178/584 (30%), Positives = 303/584 (51%), Gaps = 73/584 (12%)
Query: 28 KEEMGFLRDVFSEKSLSYLMKIHEKLRYYERQSPTPVLHSAVALAEDVMEELQAASVHSD 87
++++ FL VF ++ L L+ +++K+ AV A++V+EE+ ++D
Sbjct: 359 EKDLDFLHSVFQDQHLHTLLDLYDKINTKSSPQIRNPPSDAVQRAKEVLEEISCYPENND 418
Query: 88 ERELLQLLSTPHLRAVLMVHDTVAQKNFDP----VLPP---------LPDNIDEDFDEES 134
+EL ++L+ PH A+L HD VA + + V PP P++ + D D E+
Sbjct: 419 AKELKRILTQPHFMALLQTHDVVAHEVYSDEALRVTPPPTSPYLNGDSPESANGDMDMEN 478
Query: 135 VKIVRLVK----NKEPLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIA 190
V VRLV+ EP+G T++ +E + +V ARIM GG R G +HVGDE+RE+NGI+
Sbjct: 479 VTRVRLVQFQKNTDEPMGITLKMNELNHCIV-ARIMHGGMIHRQGTLHVGDEIREINGIS 537
Query: 191 VLHKRPDEISQILAQSQGSITLKIIPATQEED----------RLKESKVFMRALFHYNPR 240
V ++ +++ ++L + +GSIT KI+P+ + + + K ++++RA F Y+P
Sbjct: 538 VANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCEDLPSTTQPKGRQIYVRAQFEYDPA 597
Query: 241 EDRAIPCQEAGLPFQRRQVLEVVSQDDPTWWQAKRVGDTNLRAGLIPSKGFQERRLSYRR 300
+D IPC+EAG+ F+ +++++S+DD WWQ K N AGLIPS QE R++
Sbjct: 598 KDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSPELQEWRVACIA 657
Query: 301 AAGTLPSPQSLRKPPYDQPCDKETCDCEGYLKGHYVAGLRRSFRLGCRERLGGSQEGKMS 360
T Q+ +C G K Y K +
Sbjct: 658 MEKTKQEQQA-------------SCTWFGKKKKQY----------------KDKYLAKHN 688
Query: 361 SGAESPELLTYEEVARYQHQPGERPRLVVLIGSLGARLHELKQKVVAENPQHFGVAVPHT 420
+ + +L+TYEEV + P + + +VL+G+ G +K ++ ++P F +PHT
Sbjct: 689 AVFDQLDLVTYEEVVKL---PAFKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHT 745
Query: 421 TRPRKSHEKEGVEYHFVSKQAFEADLHHNKFLEHGEYKENLYGTSLEAIQAVMAKNKVCL 480
TRP K E+ G Y+FVS D+ +N++LE+G +++ +YGT LE I+ + + + +
Sbjct: 746 TRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAI 805
Query: 481 VDVEPEALKQLRTSEFKPYIIFVKPAIQEKRKTPPMSPACEDTAAPFDEQQQEMAASAAF 540
+DVEP+ALK LRT+EF P+++F+ P ++P + DE Q + +
Sbjct: 806 LDVEPQALKVLRTAEFAPFVVFI--------AAPTITPGLNE-----DESLQRLQKESDI 852
Query: 541 IDRHYGHLVDAVLVKEDLQGAYSQLKVVLEKLSKDTHWVPVSWV 584
+ R Y H D ++ ++ L+ +E + WVPVSWV
Sbjct: 853 LQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAPQWVPVSWV 896
>gi|186700627 calcium/calmodulin-dependent serine protein kinase
isoform 2 [Homo sapiens]
Length = 898
Score = 300 bits (769), Expect = 2e-81
Identities = 177/584 (30%), Positives = 300/584 (51%), Gaps = 78/584 (13%)
Query: 28 KEEMGFLRDVFSEKSLSYLMKIHEKLRYYERQSPTPVLHSAVALAEDVMEELQAASVHSD 87
++++ FL VF ++ L L+ +++K+ AV A++V+EE+ ++D
Sbjct: 365 EKDLDFLHSVFQDQHLHTLLDLYDKINTKSSPQIRNPPSDAVQRAKEVLEEISCYPENND 424
Query: 88 ERELLQLLSTPHLRAVLMVHDTVAQKNFDP----VLPP---------LPDNIDEDFDEES 134
+EL ++L+ PH A+L HD VA + + V PP P++ + D D E+
Sbjct: 425 AKELKRILTQPHFMALLQTHDVVAHEVYSDEALRVTPPPTSPYLNGDSPESANGDMDMEN 484
Query: 135 VKIVRLVK----NKEPLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIA 190
V VRLV+ EP+G T++ +E + +V ARIM GG R G +HVGDE+RE+NGI+
Sbjct: 485 VTRVRLVQFQKNTDEPMGITLKMNELNHCIV-ARIMHGGMIHRQGTLHVGDEIREINGIS 543
Query: 191 VLHKRPDEISQILAQSQGSITLKIIPATQEED----------RLKESKVFMRALFHYNPR 240
V ++ +++ ++L + +GSIT KI+P+ + + + K ++++RA F Y+P
Sbjct: 544 VANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCEDLPSTTQPKGRQIYVRAQFEYDPA 603
Query: 241 EDRAIPCQEAGLPFQRRQVLEVVSQDDPTWWQAKRVGDTNLRAGLIPSKGFQERRLSYRR 300
+D IPC+EAG+ F+ +++++S+DD WWQ K N AGLIPS QE R++
Sbjct: 604 KDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLENSKNGTAGLIPSPELQEWRVACIA 663
Query: 301 AAGTLPSPQSLRKPPYDQPCDKETCDCEGYLKGHYVAGLRRSFRLGCRERLGGSQEGKMS 360
T Q+ +C G K Y
Sbjct: 664 MEKTKQEQQA-------------SCTWFGKKKKQY---------------------KDKY 689
Query: 361 SGAESPELLTYEEVARYQHQPGERPRLVVLIGSLGARLHELKQKVVAENPQHFGVAVPHT 420
+ +L+TYEEV + P + + +VL+G+ G +K ++ ++P F +PHT
Sbjct: 690 LAKHNADLVTYEEVVKL---PAFKRKTLVLLGAHGVGRRHIKNTLITKHPDRFAYPIPHT 746
Query: 421 TRPRKSHEKEGVEYHFVSKQAFEADLHHNKFLEHGEYKENLYGTSLEAIQAVMAKNKVCL 480
TRP K E+ G Y+FVS D+ +N++LE+G +++ +YGT LE I+ + + + +
Sbjct: 747 TRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSHEDAMYGTKLETIRKIHEQGLIAI 806
Query: 481 VDVEPEALKQLRTSEFKPYIIFVKPAIQEKRKTPPMSPACEDTAAPFDEQQQEMAASAAF 540
+DVEP+ALK LRT+EF P+++F+ P ++P + DE Q + +
Sbjct: 807 LDVEPQALKVLRTAEFAPFVVFI--------AAPTITPGLNE-----DESLQRLQKESDI 853
Query: 541 IDRHYGHLVDAVLVKEDLQGAYSQLKVVLEKLSKDTHWVPVSWV 584
+ R Y H D ++ ++ L+ +E + WVPVSWV
Sbjct: 854 LQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAPQWVPVSWV 897
>gi|52630447 palmitoylated membrane protein 2 [Homo sapiens]
Length = 552
Score = 296 bits (759), Expect = 3e-80
Identities = 203/603 (33%), Positives = 312/603 (51%), Gaps = 71/603 (11%)
Query: 1 MPVLSEDS--GLHETLALLTSQLRPDSNHKEEMGFLRDVFSEKSLSYLMKIHEKLRYYER 58
MPV + +S + + L L S + ++ FLR + + L K HE+L E
Sbjct: 1 MPVAATNSETAMQQVLDNLGSLPSATGAAELDLIFLRGIMESPIVRSLAKAHERL---EE 57
Query: 59 QSPTPVLHSAVALAEDVMEEL-QAASVHSDERELLQLLSTPHLRAVLMVHDTVAQKNFDP 117
V + + L ++++ +L A S EL +L PH +++L HD+VA K ++
Sbjct: 58 TKLEAVRDNNLELVQEILRDLAHVAEQSSTAAELAHILQEPHFQSLLETHDSVASKTYET 117
Query: 118 VLPPLPDNIDEDFDEESVK--IVRLVKNK----EPLGATIRRDEHSGAVVVARIMRGGAA 171
PP +D F + V VR+V + E LG T R + G +V+ARI+ GG
Sbjct: 118 --PPPSPGLDPTFSNQPVPPDAVRMVGIRKTAGEHLGVTFRVE--GGELVIARILHGGMV 173
Query: 172 DRSGLVHVGDELREVNGIAVLHKRPDEISQILAQSQGSITLKIIPATQEEDRLKESKVFM 231
+ GL+HVGD ++EVNG V P + ++L + GS+ LKI+P+ QE ++ VF+
Sbjct: 174 AQQGLLHVGDIIKEVNGQPV-GSDPRALQELLRNASGSVILKILPSYQEPHLPRQ--VFV 230
Query: 232 RALFHYNPREDRAIPCQEAGLPFQRRQVLEVVSQDDPTWWQAKRVGDTNLRAGLIPSKGF 291
+ F Y+P D IPC+EAGL F +L++V+QDD WWQA V + AGLIPS+
Sbjct: 231 KCHFDYDPARDSLIPCKEAGLRFNAGDLLQIVNQDDANWWQACHVEGGS--AGLIPSQLL 288
Query: 292 QERRLSYRRAAGTLPSPQSLRKPPYDQPCDKETCDCEGYLKGHYVAGLRRSFRLGCRERL 351
+E+R ++ + D E G L G L
Sbjct: 289 EEKRKAFVKR-------------------DLELTPNSGTLCGS----------------L 313
Query: 352 GGSQEGKM------SSGAESPELLTYEEVARYQHQPGERPRLVVLIGSLGARLHELKQKV 405
G ++ +M ++ + ELL YEEVAR P R + +VLIG+ G LK K+
Sbjct: 314 SGKKKKRMMYLTTKNAEFDRHELLIYEEVAR---MPPFRRKTLVLIGAQGVGRRSLKNKL 370
Query: 406 VAENPQHFGVAVPHTTRPRKSHEKEGVEYHFVSKQAFEADLHHNKFLEHGEYKENLYGTS 465
+ +P +G VP+T+R K E+EG Y FVS+ EAD+ ++LEHGEY+ NLYGT
Sbjct: 371 IMWDPDRYGTTVPYTSRRPKDSEREGQGYSFVSRGEMEADVRAGRYLEHGEYEGNLYGTR 430
Query: 466 LEAIQAVMAKNKVCLVDVEPEALKQLRTSEFKPYIIFVKPAIQEKRKTPPMSPACED--- 522
+++I+ V+A KVC++DV P+A+K LRT+EF PY++F++ E + M+ A +
Sbjct: 431 IDSIRGVVAAGKVCVLDVNPQAVKVLRTAEFVPYVVFIEAPDFETLRA--MNRAALESGI 488
Query: 523 -TAAPFDEQQQEMAASAAFIDRHYGHLVDAVLVKEDLQGAYSQLKVVLEKLSKDTHWVPV 581
T + + ++ I R YGH D LV +L+ + +L+ +EKL + WVPV
Sbjct: 489 STKQLTEADLRRTVEESSRIQRGYGHYFDLCLVNSNLERTFRELQTAMEKLRTEPQWVPV 548
Query: 582 SWV 584
SWV
Sbjct: 549 SWV 551
>gi|186972120 calcium/calmodulin-dependent serine protein kinase
isoform 1 [Homo sapiens]
Length = 921
Score = 292 bits (747), Expect = 7e-79
Identities = 179/607 (29%), Positives = 301/607 (49%), Gaps = 101/607 (16%)
Query: 28 KEEMGFLRDVFSEKSLSYLMKIHEKLRYYERQSPTPVLHSAVALAEDVMEELQAASVHSD 87
++++ FL VF ++ L L+ +++K+ AV A++V+EE+ ++D
Sbjct: 365 EKDLDFLHSVFQDQHLHTLLDLYDKINTKSSPQIRNPPSDAVQRAKEVLEEISCYPENND 424
Query: 88 ERELLQLLSTPHLRAVLMVHDTVAQKNFDP----VLPP---------LPDNIDEDFDEES 134
+EL ++L+ PH A+L HD VA + + V PP P++ + D D E+
Sbjct: 425 AKELKRILTQPHFMALLQTHDVVAHEVYSDEALRVTPPPTSPYLNGDSPESANGDMDMEN 484
Query: 135 VKIVRLVK----NKEPLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIA 190
V VRLV+ EP+G T++ +E + +V ARIM GG R G +HVGDE+RE+NGI+
Sbjct: 485 VTRVRLVQFQKNTDEPMGITLKMNELNHCIV-ARIMHGGMIHRQGTLHVGDEIREINGIS 543
Query: 191 VLHKRPDEISQILAQSQGSITLKIIPA--TQEEDRLKES--------------------- 227
V ++ +++ ++L + +GSIT KI+P+ TQ ++S
Sbjct: 544 VANQTVEQLQKMLREMRGSITFKIVPSYRTQSSSCERDSPSTSRQSPANGHSSTNNSVSD 603
Query: 228 ----------KVFMRALFHYNPREDRAIPCQEAGLPFQRRQVLEVVSQDDPTWWQAKRVG 277
++++RA F Y+P +D IPC+EAG+ F+ +++++S+DD WWQ K
Sbjct: 604 LPSTTQPKGRQIYVRAQFEYDPAKDDLIPCKEAGIRFRVGDIIQIISKDDHNWWQGKLEN 663
Query: 278 DTNLRAGLIPSKGFQERRLSYRRAAGTLPSPQSLRKPPYDQPCDKETCDCEGYLKGHYVA 337
N AGLIPS QE R++ T Q+ +C G K Y
Sbjct: 664 SKNGTAGLIPSPELQEWRVACIAMEKTKQEQQA-------------SCTWFGKKKKQYK- 709
Query: 338 GLRRSFRLGCRERLGGSQEGKMSSGAESPELLTYEEVARYQHQPGERPRLVVLIGSLGAR 397
+ +L+TYEEV + P + + +VL+G+ G
Sbjct: 710 --------------------DKYLAKHNADLVTYEEVVKL---PAFKRKTLVLLGAHGVG 746
Query: 398 LHELKQKVVAENPQHFGVAVPHTTRPRKSHEKEGVEYHFVSKQAFEADLHHNKFLEHGEY 457
+K ++ ++P F +PHTTRP K E+ G Y+FVS D+ +N++LE+G +
Sbjct: 747 RRHIKNTLITKHPDRFAYPIPHTTRPPKKDEENGKNYYFVSHDQMMQDISNNEYLEYGSH 806
Query: 458 KENLYGTSLEAIQAVMAKNKVCLVDVEPEALKQLRTSEFKPYIIFVKPAIQEKRKTPPMS 517
++ +YGT LE I+ + + + ++DVEP+ALK LRT+EF P+++F+ P ++
Sbjct: 807 EDAMYGTKLETIRKIHEQGLIAILDVEPQALKVLRTAEFAPFVVFI--------AAPTIT 858
Query: 518 PACEDTAAPFDEQQQEMAASAAFIDRHYGHLVDAVLVKEDLQGAYSQLKVVLEKLSKDTH 577
P + DE Q + + + R Y H D ++ ++ L+ +E +
Sbjct: 859 PGLNE-----DESLQRLQKESDILQRTYAHYFDLTIINNEIDETIRHLEEAVELVCTAPQ 913
Query: 578 WVPVSWV 584
WVPVSWV
Sbjct: 914 WVPVSWV 920
>gi|4505237 palmitoylated membrane protein 1 [Homo sapiens]
Length = 466
Score = 256 bits (653), Expect = 5e-68
Identities = 146/456 (32%), Positives = 241/456 (52%), Gaps = 58/456 (12%)
Query: 133 ESVKIVRLVK----NKEPLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNG 188
+ V+ VRL++ +EP+G T++ +E V ARI+ GG R G +HVGDE+ E+NG
Sbjct: 64 QEVRKVRLIQFEKVTEEPMGITLKLNEKQSCTV-ARILHGGMIHRQGSLHVGDEILEING 122
Query: 189 IAVLHKRPDEISQILAQSQGSITLKIIPATQEEDRLKESKVFMRALFHYNPREDRAIPCQ 248
V + D++ + + +++G I+LK+IP ++ RL ++FMRA F Y+P++D IPC+
Sbjct: 123 TNVTNHSVDQLQKAMKETKGMISLKVIP--NQQSRLPALQMFMRAQFDYDPKKDNLIPCK 180
Query: 249 EAGLPFQRRQVLEVVSQDDPTWWQAKRVGDTNLRAGLIPSKGFQERRLSYRRAAGTLPSP 308
EAGL F +++++++DD WWQ + G + AGLIPS QE R++ A + PS
Sbjct: 181 EAGLKFATGDIIQIINKDDSNWWQGRVEGSSKESAGLIPSPELQEWRVA--SMAQSAPS- 237
Query: 309 QSLRKPPYDQPCDKETCDCEGYLKGHYVAGLRRSFRLGCRERLGGSQEGKMSSGAESPEL 368
+ P P K+ + YL H SS + ++
Sbjct: 238 ----EAPSCSPFGKKKKYKDKYLAKH-------------------------SSIFDQLDV 268
Query: 369 LTYEEVARYQHQPGERPRLVVLIGSLGARLHELKQKVVAENPQHFGVAVPHTTRPRKSHE 428
++YEEV R P + + +VLIG+ G +K ++++NP+ F VP+TTRP + E
Sbjct: 269 VSYEEVVRL---PAFKRKTLVLIGASGVGRSHIKNALLSQNPEKFVYPVPYTTRPPRKSE 325
Query: 429 KEGVEYHFVSKQAFEADLHHNKFLEHGEYKENLYGTSLEAIQAVMAKNKVCLVDVEPEAL 488
++G EYHF+S + ++ N+FLE G Y+ N++GT E + + +NK+ ++D+EP+ L
Sbjct: 326 EDGKEYHFISTEEMTRNISANEFLEFGSYQGNMFGTKFETVHQIHKQNKIAILDIEPQTL 385
Query: 489 KQLRTSEFKPYIIFVKPAIQEKRKTPPMSPACEDTAAPFDEQQQEMAASAAFIDRHYGHL 548
K +RT+E P+I+F+ P Q + E Q++ + I Y H
Sbjct: 386 KIVRTAELSPFIVFIAPTDQGTQ----------------TEALQQLQKDSEAIRSQYAHY 429
Query: 549 VDAVLVKEDLQGAYSQLKVVLEKLSKDTHWVPVSWV 584
D LV + +L+ ++ WVPVSWV
Sbjct: 430 FDLSLVNNGVDETLKKLQEAFDQACSSPQWVPVSWV 465
>gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]
Length = 749
Score = 183 bits (464), Expect = 4e-46
Identities = 138/475 (29%), Positives = 229/475 (48%), Gaps = 81/475 (17%)
Query: 138 VRLVKNKEPLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIAVLHKRPD 197
V L K LG I E + V+ I+ GG AD SG + GD++ VNGI + +
Sbjct: 319 VVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHE 378
Query: 198 EISQILAQSQGSITLKIIPATQEEDRLK-ESKV--------------------------- 229
+ + L + ++T II Q ED + E+K+
Sbjct: 379 QAAAALKGAGQTVT--IIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSL 436
Query: 230 FMRALFHYNPREDRAIPCQEAGLPFQRRQVLEVVSQDDPTWWQAKRV---GDTNLRAGLI 286
++RA+F Y+ +D +P Q GL F+ +L V++ D WWQA+RV GD+ G+I
Sbjct: 437 YVRAMFDYDKSKDSGLPSQ--GLSFKYGDILHVINASDDEWWQARRVMLEGDSE-EMGVI 493
Query: 287 PSKGFQERRLSYRRAAGTLPSPQSLRKPPYDQPCDKETCDCEGYLKGHYVAGLRRSFRLG 346
PSK ER+ R L + + KP D +G + G
Sbjct: 494 PSKRRVERKERAR-----LKTVKFNAKPG--------VIDSKGDIPG------------- 527
Query: 347 CRERLGGSQEGKMSSGAESPELLTYEEVARYQHQPGERPRLVVLIGSLGARLHELKQKVV 406
LG G + + +L+YE V R Q R V+++G + R+++ ++
Sbjct: 528 ----LGDDGYGTKTLRGQEDLILSYEPVTR---QEINYTRPVIILGPMKDRIND---DLI 577
Query: 407 AENPQHFGVAVPHTTRPRKSHEKEGVEYHFV-SKQAFEADLHHNKFLEHGEYKENLYGTS 465
+E P FG VPHTTRP++ +E +G +YHFV S++ E D+ +KF+E G+Y +NLYGTS
Sbjct: 578 SEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDNLYGTS 637
Query: 466 LEAIQAVMAKNKVCLVDVEPEALKQLRTSEFKPYIIFVKPAIQEKRKTPPMSPACEDTAA 525
+++++ V + K C++DV A+K+L+ ++ P IF+KP + P E
Sbjct: 638 VQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPR--------SLEPLMEMNKR 689
Query: 526 PFDEQQQEMAASAAFIDRHYGHLVDAVLVKEDLQGAYSQLKVVLEKLSKDTHWVP 580
+EQ ++ A +++ +G A++ + L+ Y+Q K+V+E+ S W+P
Sbjct: 690 LTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIP 744
Score = 38.1 bits (87), Expect = 0.023
Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 6/88 (6%)
Query: 133 ESVKIVRLVKNKEPLGATIRR---DEH---SGAVVVARIMRGGAADRSGLVHVGDELREV 186
E+V ++L K + LG +I ++H ++ V +I+ GGAA + G + VGD L V
Sbjct: 138 ETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMV 197
Query: 187 NGIAVLHKRPDEISQILAQSQGSITLKI 214
N ++ +E IL + + LK+
Sbjct: 198 NNYSLEEVTHEEAVAILKNTSEVVYLKV 225
>gi|218156338 chapsyn-110 isoform 1 [Homo sapiens]
Length = 975
Score = 182 bits (461), Expect = 1e-45
Identities = 137/482 (28%), Positives = 231/482 (47%), Gaps = 77/482 (15%)
Query: 138 VRLVKNKEPLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIAVLHKRPD 197
V L K LG I E + V+ I+ GG AD SG + GD++ VNGI + +
Sbjct: 527 VVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHE 586
Query: 198 EISQILAQSQGSITLKIIPATQEEDRLK-ESKV--------------------------- 229
+ + L + ++T II Q ED + E+K+
Sbjct: 587 QAAAALKGAGQTVT--IIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSL 644
Query: 230 FMRALFHYNPREDRAIPCQEAGLPFQRRQVLEVVSQDDPTWWQAKRV---GDTNLRAGLI 286
++RA+F Y+ +D +P Q GL F+ +L V++ D WWQA+RV GD+ G+I
Sbjct: 645 YVRAMFDYDKSKDSGLPSQ--GLSFKYGDILHVINASDDEWWQARRVMLEGDSE-EMGVI 701
Query: 287 PSKGFQERR-------LSYRRAAGTLPSPQSLRKPPYDQPCDKETCDCEGYLKGHYVAGL 339
PSK ER+ + + G + S S DK K ++
Sbjct: 702 PSKRRVERKERARLKTVKFNAKPGVIDSKGSFN--------DKR--------KKSFIFSR 745
Query: 340 RRSFRLGCRERLGGSQEGKMSSGAESPELLTYEEVARYQHQPGERPRLVVLIGSLGARLH 399
+ F + + QE + +L+YE V R Q R V+++G + R++
Sbjct: 746 KFPFY---KNKEQSEQETSDPERGQEDLILSYEPVTR---QEINYTRPVIILGPMKDRIN 799
Query: 400 ELKQKVVAENPQHFGVAVPHTTRPRKSHEKEGVEYHFV-SKQAFEADLHHNKFLEHGEYK 458
+ +++E P FG VPHTTRP++ +E +G +YHFV S++ E D+ +KF+E G+Y
Sbjct: 800 D---DLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYN 856
Query: 459 ENLYGTSLEAIQAVMAKNKVCLVDVEPEALKQLRTSEFKPYIIFVKPAIQEKRKTPPMSP 518
+NLYGTS+++++ V + K C++DV A+K+L+ ++ P IF+KP + P
Sbjct: 857 DNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPR--------SLEP 908
Query: 519 ACEDTAAPFDEQQQEMAASAAFIDRHYGHLVDAVLVKEDLQGAYSQLKVVLEKLSKDTHW 578
E +EQ ++ A +++ +G A++ + L+ Y+Q K+V+E+ S W
Sbjct: 909 LMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIW 968
Query: 579 VP 580
+P
Sbjct: 969 IP 970
Score = 38.1 bits (87), Expect = 0.023
Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 6/88 (6%)
Query: 133 ESVKIVRLVKNKEPLGATIRR---DEH---SGAVVVARIMRGGAADRSGLVHVGDELREV 186
E+V ++L K + LG +I ++H ++ V +I+ GGAA + G + VGD L V
Sbjct: 294 ETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMV 353
Query: 187 NGIAVLHKRPDEISQILAQSQGSITLKI 214
N ++ +E IL + + LK+
Sbjct: 354 NNYSLEEVTHEEAVAILKNTSEVVYLKV 381
>gi|91199538 chapsyn-110 isoform 2 [Homo sapiens]
Length = 870
Score = 182 bits (461), Expect = 1e-45
Identities = 137/482 (28%), Positives = 231/482 (47%), Gaps = 77/482 (15%)
Query: 138 VRLVKNKEPLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIAVLHKRPD 197
V L K LG I E + V+ I+ GG AD SG + GD++ VNGI + +
Sbjct: 422 VVLHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHE 481
Query: 198 EISQILAQSQGSITLKIIPATQEEDRLK-ESKV--------------------------- 229
+ + L + ++T II Q ED + E+K+
Sbjct: 482 QAAAALKGAGQTVT--IIAQYQPEDYARFEAKIHDLREQMMNHSMSSGSGSLRTNQKRSL 539
Query: 230 FMRALFHYNPREDRAIPCQEAGLPFQRRQVLEVVSQDDPTWWQAKRV---GDTNLRAGLI 286
++RA+F Y+ +D +P Q GL F+ +L V++ D WWQA+RV GD+ G+I
Sbjct: 540 YVRAMFDYDKSKDSGLPSQ--GLSFKYGDILHVINASDDEWWQARRVMLEGDSE-EMGVI 596
Query: 287 PSKGFQERR-------LSYRRAAGTLPSPQSLRKPPYDQPCDKETCDCEGYLKGHYVAGL 339
PSK ER+ + + G + S S DK K ++
Sbjct: 597 PSKRRVERKERARLKTVKFNAKPGVIDSKGSFN--------DKR--------KKSFIFSR 640
Query: 340 RRSFRLGCRERLGGSQEGKMSSGAESPELLTYEEVARYQHQPGERPRLVVLIGSLGARLH 399
+ F + + QE + +L+YE V R Q R V+++G + R++
Sbjct: 641 KFPFY---KNKEQSEQETSDPERGQEDLILSYEPVTR---QEINYTRPVIILGPMKDRIN 694
Query: 400 ELKQKVVAENPQHFGVAVPHTTRPRKSHEKEGVEYHFV-SKQAFEADLHHNKFLEHGEYK 458
+ +++E P FG VPHTTRP++ +E +G +YHFV S++ E D+ +KF+E G+Y
Sbjct: 695 D---DLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYN 751
Query: 459 ENLYGTSLEAIQAVMAKNKVCLVDVEPEALKQLRTSEFKPYIIFVKPAIQEKRKTPPMSP 518
+NLYGTS+++++ V + K C++DV A+K+L+ ++ P IF+KP + P
Sbjct: 752 DNLYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPR--------SLEP 803
Query: 519 ACEDTAAPFDEQQQEMAASAAFIDRHYGHLVDAVLVKEDLQGAYSQLKVVLEKLSKDTHW 578
E +EQ ++ A +++ +G A++ + L+ Y+Q K+V+E+ S W
Sbjct: 804 LMEMNKRLTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIW 863
Query: 579 VP 580
+P
Sbjct: 864 IP 865
Score = 38.1 bits (87), Expect = 0.023
Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 6/88 (6%)
Query: 133 ESVKIVRLVKNKEPLGATIRR---DEH---SGAVVVARIMRGGAADRSGLVHVGDELREV 186
E+V ++L K + LG +I ++H ++ V +I+ GGAA + G + VGD L V
Sbjct: 189 ETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMV 248
Query: 187 NGIAVLHKRPDEISQILAQSQGSITLKI 214
N ++ +E IL + + LK+
Sbjct: 249 NNYSLEEVTHEEAVAILKNTSEVVYLKV 276
>gi|119943106 synapse-associated protein 102 isoform a [Homo
sapiens]
Length = 817
Score = 181 bits (460), Expect = 1e-45
Identities = 139/493 (28%), Positives = 235/493 (47%), Gaps = 82/493 (16%)
Query: 121 PLPDNI--DEDFDEESVKIVRLVKNKEPLGATIRRDEHSGAVVVARIMRGGAADRSGLVH 178
P+P ++ +EDF E KI+ L K LG I E + V+ I+ GG AD SG +
Sbjct: 369 PIPRHMLAEEDFTREPRKII-LHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELR 427
Query: 179 VGDELREVNGIAVLHKRPDEISQILAQSQGSITLKIIPATQEEDRLKESKV--------- 229
GD + VNG+ + + ++ + L ++ S+T+ +E R ESK+
Sbjct: 428 RGDRILSVNGVNLRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRF-ESKIHDLREQMMN 486
Query: 230 ------------------FMRALFHYNPREDRAIPCQEAGLPFQRRQVLEVVSQDDPTWW 271
++RALF Y+ D +P Q GL F +L V++ D WW
Sbjct: 487 SSMSSGSGSLRTSEKRSLYVRALFDYDRTRDSCLPSQ--GLSFSYGDILHVINASDDEWW 544
Query: 272 QAKRV---GDTNLRAGLIPSKGFQERRLSYRRAAGTLPSPQSLRKPPYDQPCDKETCDCE 328
QA+ V G++ + G+IPSK E++ R + + + D P
Sbjct: 545 QARLVTPHGESE-QIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRDFP--------- 594
Query: 329 GYLKGHYVAGLRRSFRLGCRERLGGSQEGKMSSGAESPELLTYEEVARYQHQPGERPRLV 388
G +Y A + L G ++ +L+YE V R Q R V
Sbjct: 595 GLSDDYYGA-----------KNLKGQEDA----------ILSYEPVTR---QEIHYARPV 630
Query: 389 VLIGSLGARLHELKQKVVAENPQHFGVAVPHTTRPRKSHEKEGVEYHFV-SKQAFEADLH 447
+++G + R+++ +++E P FG VPHTTRPR+ +E +G +YHFV S++ E D+
Sbjct: 631 IILGPMKDRVND---DLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQMEKDIQ 687
Query: 448 HNKFLEHGEYKENLYGTSLEAIQAVMAKNKVCLVDVEPEALKQLRTSEFKPYIIFVKPAI 507
NKF+E G++ +NLYGTS+++++AV + K C++DV A+K+L+ ++ P IF+KP
Sbjct: 688 DNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAIFIKP-- 745
Query: 508 QEKRKTPPMSPACEDTAAPFDEQQQEMAASAAFIDRHYGHLVDAVLVKEDLQGAYSQLKV 567
+ E EQ ++ A +++ +G A++ + L+ Y+++K
Sbjct: 746 ------KSIEALMEMNRRQTYEQANKIYDKAMKLEQEFGEYFTAIVQGDSLEEIYNKIKQ 799
Query: 568 VLEKLSKDTHWVP 580
++E S WVP
Sbjct: 800 IIEDQSGHYIWVP 812
Score = 38.5 bits (88), Expect = 0.017
Identities = 24/88 (27%), Positives = 44/88 (50%), Gaps = 6/88 (6%)
Query: 133 ESVKIVRLVKNKEPLGATIRR---DEH---SGAVVVARIMRGGAADRSGLVHVGDELREV 186
E++ V L+K + LG +I ++H ++ + +I+ GGAA + G + +GD L V
Sbjct: 222 ETIMEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAV 281
Query: 187 NGIAVLHKRPDEISQILAQSQGSITLKI 214
N + R +E L + + LK+
Sbjct: 282 NNTNLQDVRHEEAVASLKNTSDMVYLKV 309
>gi|119943108 synapse-associated protein 102 isoform b [Homo
sapiens]
Length = 512
Score = 180 bits (457), Expect = 3e-45
Identities = 136/499 (27%), Positives = 235/499 (47%), Gaps = 83/499 (16%)
Query: 131 DEESVKIVRLVKNKEPLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIA 190
D + + L K LG I E + V+ I+ GG AD SG + GD + VNG+
Sbjct: 43 DAREPRKIILHKGSTGLGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVN 102
Query: 191 VLHKRPDEISQILAQSQGSITLKIIPATQEEDRLKESKV--------------------- 229
+ + ++ + L ++ S+T+ +E R ESK+
Sbjct: 103 LRNATHEQAAAALKRAGQSVTIVAQYRPEEYSRF-ESKIHDLREQMMNSSMSSGSGSLRT 161
Query: 230 ------FMRALFHYNPREDRAIPCQEAGLPFQRRQVLEVVSQDDPTWWQAKRV---GDTN 280
++RALF Y+ D +P Q GL F +L V++ D WWQA+ V G++
Sbjct: 162 SEKRSLYVRALFDYDRTRDSCLPSQ--GLSFSYGDILHVINASDDEWWQARLVTPHGESE 219
Query: 281 LRAGLIPSKGFQERR-------LSYRRAAGTLPSPQSL-----------RKPPYDQPCDK 322
+ G+IPSK E++ + + G + S +S+ RK P+ + K
Sbjct: 220 -QIGVIPSKKRVEKKERARLKTVKFHARTGMIESNRSIKTKRKKSFRLSRKFPFYK--SK 276
Query: 323 ETCDCEGYLKGHYVAGLRRSFRLGCRERLGGSQEGKMSSGAESPELLTYEEVARYQHQPG 382
E E ++ V + + + SS + +L+YE V R Q
Sbjct: 277 ENMAQESSIQEQGVTS--------------NTSDSESSSKGQEDAILSYEPVTR---QEI 319
Query: 383 ERPRLVVLIGSLGARLHELKQKVVAENPQHFGVAVPHTTRPRKSHEKEGVEYHFV-SKQA 441
R V+++G + R+++ +++E P FG VPHTTRPR+ +E +G +YHFV S++
Sbjct: 320 HYARPVIILGPMKDRVND---DLISEFPHKFGSCVPHTTRPRRDNEVDGQDYHFVVSREQ 376
Query: 442 FEADLHHNKFLEHGEYKENLYGTSLEAIQAVMAKNKVCLVDVEPEALKQLRTSEFKPYII 501
E D+ NKF+E G++ +NLYGTS+++++AV + K C++DV A+K+L+ ++ P I
Sbjct: 377 MEKDIQDNKFIEAGQFNDNLYGTSIQSVRAVAERGKHCILDVSGNAIKRLQQAQLYPIAI 436
Query: 502 FVKPAIQEKRKTPPMSPACEDTAAPFDEQQQEMAASAAFIDRHYGHLVDAVLVKEDLQGA 561
F+KP + E EQ ++ A +++ +G A++ + L+
Sbjct: 437 FIKP--------KSIEALMEMNRRQTYEQANKIYDKAMKLEQEFGEYFTAIVQGDSLEEI 488
Query: 562 YSQLKVVLEKLSKDTHWVP 580
Y+++K ++E S WVP
Sbjct: 489 YNKIKQIIEDQSGHYIWVP 507
>gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]
Length = 904
Score = 167 bits (423), Expect = 2e-41
Identities = 125/484 (25%), Positives = 226/484 (46%), Gaps = 71/484 (14%)
Query: 127 DEDFDEESVKIVRLVKNKEPLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREV 186
D++ E K+V L + LG I E + ++ I+ GG AD SG + GD + V
Sbjct: 457 DDEITREPRKVV-LHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISV 515
Query: 187 NGIAVLHKRPDEISQILAQSQGSITLKIIPATQEEDRLK--------------------- 225
N + + ++ + L + ++T+ +E R +
Sbjct: 516 NSVDLRAASHEQAAAALKNAGQAVTIVAQYRPEEYSRFEAKIHDLREQMMNSSISSGSGS 575
Query: 226 -----ESKVFMRALFHYNPREDRAIPCQEAGLPFQRRQVLEVVSQDDPTWWQAKRV---G 277
+ +++RALF Y+ +D +P Q GL F+ +L V++ D WWQA++V G
Sbjct: 576 LRTSQKRSLYVRALFDYDKTKDSGLPSQ--GLNFKFGDILHVINASDDEWWQARQVTPDG 633
Query: 278 DTNLRAGLIPSKGFQERRLSYRRAAGTLPSPQSLRKPPYDQPCDKETCDCEGYLKGHYVA 337
+++ G+IPSK E++ RA S + + P D +
Sbjct: 634 ESD-EVGVIPSKRRVEKK---ERARLKTVKFNSKTRDKGEIPDDMGS------------- 676
Query: 338 GLRRSFRLGCRERLGGSQEGKMSSGAESPELLTYEEVARYQHQPGERPRLVVLIGSLGAR 397
G + + + + S + +L+YE V Q R V+++G + R
Sbjct: 677 -------KGLKHVTSNASDSESSYRGQEEYVLSYEPV---NQQEVNYTRPVIILGPMKDR 726
Query: 398 LHELKQKVVAENPQHFGVAVPHTTRPRKSHEKEGVEYHFV-SKQAFEADLHHNKFLEHGE 456
+++ +++E P FG VPHTTRP++ +E +G +YHFV S++ E D+ +KF+E G+
Sbjct: 727 IND---DLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTSREQMEKDIQEHKFIEAGQ 783
Query: 457 YKENLYGTSLEAIQAVMAKNKVCLVDVEPEALKQLRTSEFKPYIIFVKPAIQEKRKTPPM 516
Y +LYGTS+++++ V K K C++DV A+K+L+ ++ P IF+KP E
Sbjct: 784 YNNHLYGTSVQSVREVAEKGKHCILDVSGNAIKRLQIAQLYPISIFIKPKSMEN------ 837
Query: 517 SPACEDTAAPFDEQQQEMAASAAFIDRHYGHLVDAVLVKEDLQGAYSQLKVVLEKLSKDT 576
E +EQ ++ A +++ + A++ + L+ Y+Q+K ++E+ S
Sbjct: 838 --IMEMNKRLTEEQARKTFERAMKLEQEFTEHFTAIVQGDTLEDIYNQVKQIIEEQSGSY 895
Query: 577 HWVP 580
WVP
Sbjct: 896 IWVP 899
Score = 40.4 bits (93), Expect = 0.005
Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 6/92 (6%)
Query: 133 ESVKIVRLVKNKEPLGATIRR---DEH---SGAVVVARIMRGGAADRSGLVHVGDELREV 186
E + ++L+K + LG +I ++H ++ V +I+ GGAA + G + +GD+L V
Sbjct: 315 EKIMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAV 374
Query: 187 NGIAVLHKRPDEISQILAQSQGSITLKIIPAT 218
N + + +E L + + LK+ T
Sbjct: 375 NNVCLEEVTHEEAVTALKNTSDFVYLKVAKPT 406
>gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]
Length = 926
Score = 167 bits (423), Expect = 2e-41
Identities = 130/502 (25%), Positives = 235/502 (46%), Gaps = 85/502 (16%)
Query: 127 DEDFDEESVKIVRLVKNKEPLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREV 186
D++ E K+V L + LG I E + ++ I+ GG AD SG + GD + V
Sbjct: 457 DDEITREPRKVV-LHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISV 515
Query: 187 NGIAVLHKRPDEISQILAQSQGSITLKIIPATQEEDRLK--------------------- 225
N + + ++ + L + ++T+ +E R +
Sbjct: 516 NSVDLRAASHEQAAAALKNAGQAVTIVAQYRPEEYSRFEAKIHDLREQMMNSSISSGSGS 575
Query: 226 -----ESKVFMRALFHYNPREDRAIPCQEAGLPFQRRQVLEVVSQDDPTWWQAKRV---G 277
+ +++RALF Y+ +D +P Q GL F+ +L V++ D WWQA++V G
Sbjct: 576 LRTSQKRSLYVRALFDYDKTKDSGLPSQ--GLNFKFGDILHVINASDDEWWQARQVTPDG 633
Query: 278 DTNLRAGLIPSKGFQERRLSYRRA-----AGTLPSPQSL----------RKPPYDQPCDK 322
+++ G+IPSK E++ R + T QS RK P+ + D+
Sbjct: 634 ESD-EVGVIPSKRRVEKKERARLKTVKFNSKTRDKGQSFNDKRKKNLFSRKFPFYKNKDQ 692
Query: 323 ---ETCDCEGYLKGHYVAGLRRSFRLGCRERLGGSQEGKMSSGAESPELLTYEEVARYQH 379
ET D + ++ + + + + S + +L+YE V
Sbjct: 693 SEQETSDADQHVTSN-------------------ASDSESSYRGQEEYVLSYEPV---NQ 730
Query: 380 QPGERPRLVVLIGSLGARLHELKQKVVAENPQHFGVAVPHTTRPRKSHEKEGVEYHFV-S 438
Q R V+++G + R+++ +++E P FG VPHTTRP++ +E +G +YHFV S
Sbjct: 731 QEVNYTRPVIILGPMKDRIND---DLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVTS 787
Query: 439 KQAFEADLHHNKFLEHGEYKENLYGTSLEAIQAVMAKNKVCLVDVEPEALKQLRTSEFKP 498
++ E D+ +KF+E G+Y +LYGTS+++++ V K K C++DV A+K+L+ ++ P
Sbjct: 788 REQMEKDIQEHKFIEAGQYNNHLYGTSVQSVREVAEKGKHCILDVSGNAIKRLQIAQLYP 847
Query: 499 YIIFVKPAIQEKRKTPPMSPACEDTAAPFDEQQQEMAASAAFIDRHYGHLVDAVLVKEDL 558
IF+KP E E +EQ ++ A +++ + A++ + L
Sbjct: 848 ISIFIKPKSMEN--------IMEMNKRLTEEQARKTFERAMKLEQEFTEHFTAIVQGDTL 899
Query: 559 QGAYSQLKVVLEKLSKDTHWVP 580
+ Y+Q+K ++E+ S WVP
Sbjct: 900 EDIYNQVKQIIEEQSGSYIWVP 921
Score = 40.4 bits (93), Expect = 0.005
Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 6/92 (6%)
Query: 133 ESVKIVRLVKNKEPLGATIRR---DEH---SGAVVVARIMRGGAADRSGLVHVGDELREV 186
E + ++L+K + LG +I ++H ++ V +I+ GGAA + G + +GD+L V
Sbjct: 315 EKIMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAV 374
Query: 187 NGIAVLHKRPDEISQILAQSQGSITLKIIPAT 218
N + + +E L + + LK+ T
Sbjct: 375 NNVCLEEVTHEEAVTALKNTSDFVYLKVAKPT 406
>gi|218156270 chapsyn-110 isoform 4 [Homo sapiens]
Length = 334
Score = 165 bits (418), Expect = 9e-41
Identities = 108/360 (30%), Positives = 186/360 (51%), Gaps = 51/360 (14%)
Query: 225 KESKVFMRALFHYNPREDRAIPCQEAGLPFQRRQVLEVVSQDDPTWWQAKRV---GDTNL 281
++ +++RA+F Y+ +D +P Q GL F+ +L V++ D WWQA+RV GD+
Sbjct: 17 QKRSLYVRAMFDYDKSKDSGLPSQ--GLSFKYGDILHVINASDDEWWQARRVMLEGDSE- 73
Query: 282 RAGLIPSKGFQERRLSYRRAAGTLPSPQSLRKPPYDQPCDKETCDCEGYLKGHYVAGLRR 341
G+IPSK ER+ R L + + KP D +G + G
Sbjct: 74 EMGVIPSKRRVERKERAR-----LKTVKFNAKPG--------VIDSKGDIPG-------- 112
Query: 342 SFRLGCRERLGGSQEGKMSSGAESPELLTYEEVARYQHQPGERPRLVVLIGSLGARLHEL 401
LG G + + +L+YE V R Q R V+++G + R+++
Sbjct: 113 ---------LGDDGYGTKTLRGQEDLILSYEPVTR---QEINYTRPVIILGPMKDRIND- 159
Query: 402 KQKVVAENPQHFGVAVPHTTRPRKSHEKEGVEYHFV-SKQAFEADLHHNKFLEHGEYKEN 460
+++E P FG VPHTTRP++ +E +G +YHFV S++ E D+ +KF+E G+Y +N
Sbjct: 160 --DLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVISREQMEKDIQEHKFIEAGQYNDN 217
Query: 461 LYGTSLEAIQAVMAKNKVCLVDVEPEALKQLRTSEFKPYIIFVKPAIQEKRKTPPMSPAC 520
LYGTS+++++ V + K C++DV A+K+L+ ++ P IF+KP + P
Sbjct: 218 LYGTSVQSVRFVAERGKHCILDVSGNAIKRLQVAQLYPIAIFIKPR--------SLEPLM 269
Query: 521 EDTAAPFDEQQQEMAASAAFIDRHYGHLVDAVLVKEDLQGAYSQLKVVLEKLSKDTHWVP 580
E +EQ ++ A +++ +G A++ + L+ Y+Q K+V+E+ S W+P
Sbjct: 270 EMNKRLTEEQAKKTYDRAIKLEQEFGEYFTAIVQGDTLEDIYNQCKLVIEEQSGPFIWIP 329
>gi|4557529 post-synaptic density protein 95 isoform 1 [Homo
sapiens]
Length = 767
Score = 147 bits (370), Expect = 3e-35
Identities = 126/484 (26%), Positives = 213/484 (44%), Gaps = 98/484 (20%)
Query: 127 DEDFDEESVKIVRLVKNKEPLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREV 186
+ED E +IV + + LG I E + ++ I+ GG AD SG + GD++ V
Sbjct: 347 EEDIPREPRRIV-IHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSV 405
Query: 187 NGIAVLHKRPDEISQILAQSQGSITLKIIPATQEEDRLKESKV----------------- 229
NG+ + + ++ + L + ++T+ I EE E+K+
Sbjct: 406 NGVDLRNASHEQAAIALKNAGQTVTI-IAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTA 464
Query: 230 ----------FMRALFHYNPREDRAIPCQEAGLPFQRRQVLEVVSQDDPTWWQAKRVGDT 279
++RALF Y+ +D Q L F+ VL V+ D WWQA+RV
Sbjct: 465 SLRSNPKRGFYIRALFDYDKTKDCGFLSQ--ALSFRFGDVLHVIDASDEEWWQARRVHSD 522
Query: 280 NLR--AGLIPSKGFQERRLSYRRAAGTLPSPQSLRKPPYDQPCDKETCDCEGYLKGHYVA 337
+ G IPSK ER
Sbjct: 523 SETDDIGFIPSKRRVER------------------------------------------- 539
Query: 338 GLRRSFRLGCRERLGGSQEGKMSSGAESPELLTYEEVARYQHQPGERPRLVVLIGSLGAR 397
R RL ++ GS G S G E +L+YE V + + R ++++G R
Sbjct: 540 --REWSRLKAKD--WGSSSG--SQGRED-SVLSYETVTQMEVHYA---RPIIILGPTKDR 589
Query: 398 LHELKQKVVAENPQHFGVAVPHTTRPRKSHEKEGVEYHFVS-KQAFEADLHHNKFLEHGE 456
++ +++E P FG VPHTTRP++ +E +G +YHFVS ++ E D+ +KF+E G+
Sbjct: 590 AND---DLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQ 646
Query: 457 YKENLYGTSLEAIQAVMAKNKVCLVDVEPEALKQLRTSEFKPYIIFVKPAIQEKRKTPPM 516
Y +LYGTS+++++ V + K C++DV A+++L+ + P IF++P E
Sbjct: 647 YNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLEN------ 700
Query: 517 SPACEDTAAPFDEQQQEMAASAAFIDRHYGHLVDAVLVKEDLQGAYSQLKVVLEKLSKDT 576
E +EQ ++ A +++ + A++ + + Y ++K V+E LS
Sbjct: 701 --VLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPY 758
Query: 577 HWVP 580
WVP
Sbjct: 759 IWVP 762
Score = 37.4 bits (85), Expect = 0.039
Identities = 22/88 (25%), Positives = 45/88 (51%), Gaps = 6/88 (6%)
Query: 133 ESVKIVRLVKNKEPLGATIRR---DEH---SGAVVVARIMRGGAADRSGLVHVGDELREV 186
E V ++L+K + LG +I ++H ++ V +I+ GGAA + G + +GD++ V
Sbjct: 199 EKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAV 258
Query: 187 NGIAVLHKRPDEISQILAQSQGSITLKI 214
N + + ++ L + + LK+
Sbjct: 259 NSVGLEDVMHEDAVAALKNTYDVVYLKV 286
>gi|192447426 post-synaptic density protein 95 isoform 2 [Homo
sapiens]
Length = 721
Score = 147 bits (370), Expect = 3e-35
Identities = 126/484 (26%), Positives = 213/484 (44%), Gaps = 98/484 (20%)
Query: 127 DEDFDEESVKIVRLVKNKEPLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREV 186
+ED E +IV + + LG I E + ++ I+ GG AD SG + GD++ V
Sbjct: 301 EEDIPREPRRIV-IHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSV 359
Query: 187 NGIAVLHKRPDEISQILAQSQGSITLKIIPATQEEDRLKESKV----------------- 229
NG+ + + ++ + L + ++T+ I EE E+K+
Sbjct: 360 NGVDLRNASHEQAAIALKNAGQTVTI-IAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTA 418
Query: 230 ----------FMRALFHYNPREDRAIPCQEAGLPFQRRQVLEVVSQDDPTWWQAKRVGDT 279
++RALF Y+ +D Q L F+ VL V+ D WWQA+RV
Sbjct: 419 SLRSNPKRGFYIRALFDYDKTKDCGFLSQ--ALSFRFGDVLHVIDASDEEWWQARRVHSD 476
Query: 280 NLR--AGLIPSKGFQERRLSYRRAAGTLPSPQSLRKPPYDQPCDKETCDCEGYLKGHYVA 337
+ G IPSK ER
Sbjct: 477 SETDDIGFIPSKRRVER------------------------------------------- 493
Query: 338 GLRRSFRLGCRERLGGSQEGKMSSGAESPELLTYEEVARYQHQPGERPRLVVLIGSLGAR 397
R RL ++ GS G S G E +L+YE V + + R ++++G R
Sbjct: 494 --REWSRLKAKD--WGSSSG--SQGRED-SVLSYETVTQMEVHYA---RPIIILGPTKDR 543
Query: 398 LHELKQKVVAENPQHFGVAVPHTTRPRKSHEKEGVEYHFVS-KQAFEADLHHNKFLEHGE 456
++ +++E P FG VPHTTRP++ +E +G +YHFVS ++ E D+ +KF+E G+
Sbjct: 544 AND---DLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQ 600
Query: 457 YKENLYGTSLEAIQAVMAKNKVCLVDVEPEALKQLRTSEFKPYIIFVKPAIQEKRKTPPM 516
Y +LYGTS+++++ V + K C++DV A+++L+ + P IF++P E
Sbjct: 601 YNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLEN------ 654
Query: 517 SPACEDTAAPFDEQQQEMAASAAFIDRHYGHLVDAVLVKEDLQGAYSQLKVVLEKLSKDT 576
E +EQ ++ A +++ + A++ + + Y ++K V+E LS
Sbjct: 655 --VLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPY 712
Query: 577 HWVP 580
WVP
Sbjct: 713 IWVP 716
Score = 37.4 bits (85), Expect = 0.039
Identities = 22/88 (25%), Positives = 45/88 (51%), Gaps = 6/88 (6%)
Query: 133 ESVKIVRLVKNKEPLGATIRR---DEH---SGAVVVARIMRGGAADRSGLVHVGDELREV 186
E V ++L+K + LG +I ++H ++ V +I+ GGAA + G + +GD++ V
Sbjct: 153 EKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAV 212
Query: 187 NGIAVLHKRPDEISQILAQSQGSITLKI 214
N + + ++ L + + LK+
Sbjct: 213 NSVGLEDVMHEDAVAALKNTYDVVYLKV 240
>gi|226874833 guanylate kinase 1 isoform b [Homo sapiens]
Length = 197
Score = 108 bits (269), Expect = 2e-23
Identities = 61/190 (32%), Positives = 104/190 (54%), Gaps = 9/190 (4%)
Query: 385 PRLVVLIGSLGARLHELKQKVVAENPQHFGVAVPHTTRPRKSHEKEGVEYHFVSKQAFEA 444
PR VVL G GA L ++++ E+ FG +V HTTR + E+ G +Y+FV+++ +
Sbjct: 4 PRPVVLSGPSGAGKSTLLKRLLQEHSGIFGFSVSHTTRNPRPGEENGKDYYFVTREVMQR 63
Query: 445 DLHHNKFLEHGEYKENLYGTSLEAIQAVMAKNKVCLVDVEPEALKQLRTSEFKPYIIFVK 504
D+ F+EH E+ NLYGTS A+QAV A N++C++DV+ + ++ ++ ++ +P I V+
Sbjct: 64 DIAAGDFIEHAEFSGNLYGTSKVAVQAVQAMNRICVLDVDLQGVRNIKATDLRPIYISVQ 123
Query: 505 PA---IQEKRKTPPMSPACEDTAAPFDEQQQEMAASAAFIDRHYGHLVDAVLVKEDLQGA 561
P + E+R + E Q +M +S L D V++ + L A
Sbjct: 124 PPSLHVLEQRLRQRNTETEESLVKRLAAAQADMESSKE------PGLFDVVIINDSLDQA 177
Query: 562 YSQLKVVLEK 571
Y++LK L +
Sbjct: 178 YAELKEALSE 187
>gi|226874831 guanylate kinase 1 isoform a [Homo sapiens]
Length = 218
Score = 108 bits (269), Expect = 2e-23
Identities = 61/190 (32%), Positives = 104/190 (54%), Gaps = 9/190 (4%)
Query: 385 PRLVVLIGSLGARLHELKQKVVAENPQHFGVAVPHTTRPRKSHEKEGVEYHFVSKQAFEA 444
PR VVL G GA L ++++ E+ FG +V HTTR + E+ G +Y+FV+++ +
Sbjct: 25 PRPVVLSGPSGAGKSTLLKRLLQEHSGIFGFSVSHTTRNPRPGEENGKDYYFVTREVMQR 84
Query: 445 DLHHNKFLEHGEYKENLYGTSLEAIQAVMAKNKVCLVDVEPEALKQLRTSEFKPYIIFVK 504
D+ F+EH E+ NLYGTS A+QAV A N++C++DV+ + ++ ++ ++ +P I V+
Sbjct: 85 DIAAGDFIEHAEFSGNLYGTSKVAVQAVQAMNRICVLDVDLQGVRNIKATDLRPIYISVQ 144
Query: 505 PA---IQEKRKTPPMSPACEDTAAPFDEQQQEMAASAAFIDRHYGHLVDAVLVKEDLQGA 561
P + E+R + E Q +M +S L D V++ + L A
Sbjct: 145 PPSLHVLEQRLRQRNTETEESLVKRLAAAQADMESSKE------PGLFDVVIINDSLDQA 198
Query: 562 YSQLKVVLEK 571
Y++LK L +
Sbjct: 199 YAELKEALSE 208
>gi|4504221 guanylate kinase 1 isoform b [Homo sapiens]
Length = 197
Score = 108 bits (269), Expect = 2e-23
Identities = 61/190 (32%), Positives = 104/190 (54%), Gaps = 9/190 (4%)
Query: 385 PRLVVLIGSLGARLHELKQKVVAENPQHFGVAVPHTTRPRKSHEKEGVEYHFVSKQAFEA 444
PR VVL G GA L ++++ E+ FG +V HTTR + E+ G +Y+FV+++ +
Sbjct: 4 PRPVVLSGPSGAGKSTLLKRLLQEHSGIFGFSVSHTTRNPRPGEENGKDYYFVTREVMQR 63
Query: 445 DLHHNKFLEHGEYKENLYGTSLEAIQAVMAKNKVCLVDVEPEALKQLRTSEFKPYIIFVK 504
D+ F+EH E+ NLYGTS A+QAV A N++C++DV+ + ++ ++ ++ +P I V+
Sbjct: 64 DIAAGDFIEHAEFSGNLYGTSKVAVQAVQAMNRICVLDVDLQGVRNIKATDLRPIYISVQ 123
Query: 505 PA---IQEKRKTPPMSPACEDTAAPFDEQQQEMAASAAFIDRHYGHLVDAVLVKEDLQGA 561
P + E+R + E Q +M +S L D V++ + L A
Sbjct: 124 PPSLHVLEQRLRQRNTETEESLVKRLAAAQADMESSKE------PGLFDVVIINDSLDQA 177
Query: 562 YSQLKVVLEK 571
Y++LK L +
Sbjct: 178 YAELKEALSE 187
>gi|21389483 leucine-rich repeats and guanylate kinase domain
containing [Homo sapiens]
Length = 825
Score = 65.5 bits (158), Expect = 1e-10
Identities = 45/189 (23%), Positives = 85/189 (44%), Gaps = 10/189 (5%)
Query: 387 LVVLIGSLGARLHELKQKVVAENPQHFGVAVPHTTRPRKSHEKEGVEYHFVSKQAFEADL 446
+++L G EL ++ + +F HTTRP E + V+YHF+S+ F+ +
Sbjct: 416 MLILAGPEACGKRELAHRLCRQFSTYFRYGACHTTRPPYFGEGDRVDYHFISQDVFDEMV 475
Query: 447 HHNKFLEHGEYKENLYGTSLEAIQAVMAKNKVCLVDVEPEALKQLRTSEFKPYIIFVKPA 506
+ KF+ Y + YG + + ++ + + +E E ++ L+ S F+P I V P
Sbjct: 476 NMGKFILTFSYGNHKYGLNRDTVEGIARDGLASCIHMEIEGVRSLKYSYFEPRYILVVPM 535
Query: 507 IQEKRKTPPMSPACEDTAAPFDEQQQEMAASAA----FIDRHYGHLVDAVLVKEDLQGAY 562
+EK + F + E A S I++++ D V+ +DL AY
Sbjct: 536 NKEKYE------GYLRRKGLFSRAEIEFAVSRVDLYIKINQNFPGYFDEVINADDLDVAY 589
Query: 563 SQLKVVLEK 571
+L ++ +
Sbjct: 590 QKLSQLIRE 598
>gi|95089461 discs large homolog 5 [Homo sapiens]
Length = 1919
Score = 61.2 bits (147), Expect = 2e-09
Identities = 102/496 (20%), Positives = 198/496 (39%), Gaps = 67/496 (13%)
Query: 106 VHDTVAQKNFDPVLPPLPDN---IDEDFDEESV--KIVRLVKNKEPLGATIRRDEHSGAV 160
V D + +++ P PP + I D +++++ ++V + K++ LG + G
Sbjct: 1466 VIDPLMEQDEGPSTPPAKQSSSRIAGDANKKTLEPRVVFIKKSQLELGVHLCGGNLHGVF 1525
Query: 161 VVARIMRGGAADRSGLVHVGDELREVNGIAVLHKRPDEISQILAQSQGSITLKIIPATQE 220
V A GLV GD + E + V +K +E+ + + + + LK+ +E
Sbjct: 1526 VAEVEDDSPAKGPDGLVP-GDLILEYGSLDVRNKTVEEVYVEMLKPRDGVRLKVQYRPEE 1584
Query: 221 EDRLKE---SKVFMRALFHYNPREDRAIPCQEAGLPFQRRQVLEV---VSQDDPTWWQAK 274
+ K ++RAL+ DR ++ L F++ +L V + Q W A
Sbjct: 1585 FTKAKGLPGDSFYIRALY------DRLADVEQE-LSFKKDDILYVDDTLPQGTFGSWMAW 1637
Query: 275 RVGDT--NLRAGLIPSKGFQERRLSYRRAAGTLPSPQSLRKPPYDQPCDKETCDCEGYLK 332
++ + ++ G IPSK ++ S R + + S K
Sbjct: 1638 QLDENAQKIQRGQIPSKYVMDQEFSRRLSMSEVKDDNSATKT------------------ 1679
Query: 333 GHYVAGLRRSF-RLGCRERLGGSQEGK---MSSGAESPELLTYEEVARYQHQPGERPRLV 388
A RRSF R + + GS++GK S + +E+ +Q ++
Sbjct: 1680 --LSAAARRSFFRRKHKHKRSGSKDGKDLLALDAFSSDSIPLFEDSVSLAYQRVQKVDCT 1737
Query: 389 VL--IGSLGARLHELKQKVVAENPQHFGVAVPHTTRPRKSHEKEGVEYHFVSKQAFEADL 446
L + LG L +K+ +V E P F + +E S+QA E +
Sbjct: 1738 ALRPVLILGPLLDVVKEMLVNEAPGKFC--------------RCPLEVMKASQQAIERGV 1783
Query: 447 HHNKFLEHGEYKENLYGTSLEAIQAVMAKNKVCLVDVEPEALKQLRTSEFKPYIIFV--K 504
F+++ + T++ +I+ + KN+ CL+D+ P A+++L P +IF+ K
Sbjct: 1784 KDCLFVDYKRRSGHFDVTTVASIKEITEKNRHCLLDIAPHAIERLHHMHIYPIVIFIHYK 1843
Query: 505 PAIQEKRKTPPMSPACEDTAAPFDEQQQEMAASAAFIDRHYGHLVDAVLVKEDLQGAYSQ 564
A K + P+ + T +E +A +++ Y V+ L +Q
Sbjct: 1844 SAKHIKEQRDPIYLRDKVT----QRHSKEQFEAAQKLEQEYSRYFTGVIQGGALSSICTQ 1899
Query: 565 LKVVLEKLSKDTHWVP 580
+ ++ + W+P
Sbjct: 1900 ILAMVNQEQNKVLWIP 1915
Score = 40.8 bits (94), Expect = 0.003
Identities = 26/80 (32%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Query: 133 ESVKIVRLVKNKEPLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIAVL 192
E + V++ K EPLG +I E G + V+++ G A ++GL + GD+L E NGI +
Sbjct: 1346 EEPRHVKVQKGSEPLGISIVSGE-KGGIYVSKVTVGSIAHQAGLEY-GDQLLEFNGINLR 1403
Query: 193 HKRPDEISQILAQSQGSITL 212
+ I+ Q +IT+
Sbjct: 1404 SATEQQARLIIGQQCDTITI 1423
Score = 40.0 bits (92), Expect = 0.006
Identities = 24/90 (26%), Positives = 41/90 (45%), Gaps = 5/90 (5%)
Query: 146 PLGATIRRDEHSG-----AVVVARIMRGGAADRSGLVHVGDELREVNGIAVLHKRPDEIS 200
PL + + SG V A ++ G A + G + VGD + +NGIA+ +K +E
Sbjct: 719 PLHINLSGQKDSGISLENGVYAAAVLPGSPAAKEGSLAVGDRIVAINGIALDNKSLNECE 778
Query: 201 QILAQSQGSITLKIIPATQEEDRLKESKVF 230
+L Q S+TL ++ + +F
Sbjct: 779 SLLRSCQDSLTLSLLKVFPQSSSWSGQNIF 808
>gi|82659097 par-6 partitioning defective 6 homolog alpha isoform 2
[Homo sapiens]
Length = 345
Score = 55.8 bits (133), Expect = 1e-07
Identities = 40/138 (28%), Positives = 68/138 (49%), Gaps = 19/138 (13%)
Query: 104 LMVHDTVAQKNFDPVLPPLPDN-------IDEDFDEESVKIVRLVKN--KEPLGATIRRD 154
L++ + P+L LP + ID D E+ + VRL K+ PLG IR
Sbjct: 116 LLLRPVAPLRTRPPLLISLPQDFRQVSSVIDVDLLPETHRRVRLHKHGSDRPLGFYIRDG 175
Query: 155 ----------EHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIAVLHKRPDEISQILA 204
E + ++R++RGG A+ +GL+ V DE+ EVNGI V K D+++ ++
Sbjct: 176 MSVRVAPQGLERVPGIFISRLVRGGLAESTGLLAVSDEILEVNGIEVAGKTLDQVTDMMV 235
Query: 205 QSQGSITLKIIPATQEED 222
+ ++ + + PA Q +
Sbjct: 236 ANSHNLIVTVKPANQRNN 253
>gi|8394417 par-6 partitioning defective 6 homolog alpha isoform 1
[Homo sapiens]
Length = 346
Score = 55.8 bits (133), Expect = 1e-07
Identities = 40/138 (28%), Positives = 68/138 (49%), Gaps = 19/138 (13%)
Query: 104 LMVHDTVAQKNFDPVLPPLPDN-------IDEDFDEESVKIVRLVKN--KEPLGATIRRD 154
L++ + P+L LP + ID D E+ + VRL K+ PLG IR
Sbjct: 117 LLLRPVAPLRTRPPLLISLPQDFRQVSSVIDVDLLPETHRRVRLHKHGSDRPLGFYIRDG 176
Query: 155 ----------EHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIAVLHKRPDEISQILA 204
E + ++R++RGG A+ +GL+ V DE+ EVNGI V K D+++ ++
Sbjct: 177 MSVRVAPQGLERVPGIFISRLVRGGLAESTGLLAVSDEILEVNGIEVAGKTLDQVTDMMV 236
Query: 205 QSQGSITLKIIPATQEED 222
+ ++ + + PA Q +
Sbjct: 237 ANSHNLIVTVKPANQRNN 254
>gi|62955042 PAR-6 beta [Homo sapiens]
Length = 372
Score = 55.5 bits (132), Expect = 1e-07
Identities = 36/120 (30%), Positives = 63/120 (52%), Gaps = 12/120 (10%)
Query: 121 PLPDNIDEDFDEESVKIVRLVK--NKEPLGATIRRD----------EHSGAVVVARIMRG 168
P+ ID D E+ + VRL K ++PLG IR E + ++R++ G
Sbjct: 141 PVSSIIDVDILPETHRRVRLYKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGIFISRLVPG 200
Query: 169 GAADRSGLVHVGDELREVNGIAVLHKRPDEISQILAQSQGSITLKIIPATQEEDRLKESK 228
G A +GL+ V DE+ EVNGI V K D+++ ++ + ++ + + PA Q + ++ S+
Sbjct: 201 GLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVRPANQRNNVVRNSR 260
>gi|14210518 PAR-6 gamma protein [Homo sapiens]
Length = 376
Score = 53.1 bits (126), Expect = 7e-07
Identities = 39/134 (29%), Positives = 70/134 (52%), Gaps = 16/134 (11%)
Query: 121 PLPDNIDEDFDEESVKIVRLVKN--KEPLG------ATIRRDEHS----GAVVVARIMRG 168
P+ ID D E+ + VRL ++ ++PLG A++R H + ++R++ G
Sbjct: 142 PVSSIIDVDLVPETHRRVRLHRHGCEKPLGFYIRDGASVRVTPHGLEKVPGIFISRMVPG 201
Query: 169 GAADRSGLVHVGDELREVNGIAVLHKRPDEISQILAQSQGSITLKIIPATQEEDRLKESK 228
G A+ +GL+ V DE+ EVNGI V K D+++ ++ + ++ + + PA Q + ++
Sbjct: 202 GLAESTGLLAVNDEVLEVNGIEVAGKTLDQVTDMMIANSHNLIVTVKPANQRNNVVRGG- 260
Query: 229 VFMRALFHYNPRED 242
RAL P D
Sbjct: 261 ---RALGSSGPPSD 271
>gi|223890252 glutamate receptor interacting protein 1 [Homo
sapiens]
Length = 1076
Score = 51.6 bits (122), Expect = 2e-06
Identities = 38/133 (28%), Positives = 65/133 (48%), Gaps = 7/133 (5%)
Query: 124 DNIDEDFDEESVKIVRLVKNKE---PLGATIR-RDEHSGAVVVARIMRGGAADRSGLVHV 179
DN DE E S I+ V+ K PLG TI +E ++++ + +GG A+R+G +H+
Sbjct: 607 DNSDEQ--ESSGAIIYTVELKRYGGPLGITISGTEEPFDPIIISSLTKGGLAERTGAIHI 664
Query: 180 GDELREVNGIAVLHKRPDEISQILAQSQGSITLKIIPATQEEDRLKESKVFMRA-LFHYN 238
GD + +N ++ K E +L + ++TLKI T + K + + L
Sbjct: 665 GDRILAINSSSLKGKPLSEAIHLLQMAGETVTLKIKKQTDAQSASSPKKFPISSHLSDLG 724
Query: 239 PREDRAIPCQEAG 251
E+ + P Q+ G
Sbjct: 725 DVEEDSSPAQKPG 737
Score = 42.0 bits (97), Expect = 0.002
Identities = 21/66 (31%), Positives = 36/66 (54%)
Query: 160 VVVARIMRGGAADRSGLVHVGDELREVNGIAVLHKRPDEISQILAQSQGSITLKIIPATQ 219
+V+ +I ADR G +HVGD + ++G ++ + E +Q LA + + L+I+P Q
Sbjct: 278 IVIDKIKSASIADRCGALHVGDHILSIDGTSMEYCTLAEATQFLANTTDQVKLEILPHHQ 337
Query: 220 EEDRLK 225
LK
Sbjct: 338 TRLALK 343
Score = 40.0 bits (92), Expect = 0.006
Identities = 32/101 (31%), Positives = 50/101 (49%), Gaps = 4/101 (3%)
Query: 116 DPVLPPLPDNIDEDFDEESVKIVRLVKNK-EPLGATIRRD-EHSGAVVVARIMRGGAADR 173
D L +I E+F +V V L+K + LG T+ + G V+ + +GG A R
Sbjct: 34 DGALAVRRQSIPEEFKGSTV--VELMKKEGTTLGLTVSGGIDKDGKPRVSNLRQGGIAAR 91
Query: 174 SGLVHVGDELREVNGIAVLHKRPDEISQILAQSQGSITLKI 214
S + VGD ++ VNGI + R DEI +L + L++
Sbjct: 92 SDQLDVGDYIKAVNGINLAKFRHDEIISLLKNVGERVVLEV 132
Score = 38.1 bits (87), Expect = 0.023
Identities = 27/73 (36%), Positives = 32/73 (43%), Gaps = 5/73 (6%)
Query: 138 VRLVKNKEPLGATIRRDEH-----SGAVVVARIMRGGAADRSGLVHVGDELREVNGIAVL 192
V L K G IR H S VV+ + GG ADR G + GD L V+GI +L
Sbjct: 153 VTLHKEGNTFGFVIRGGAHDDRNKSRPVVITCVRPGGPADREGTIKPGDRLLSVDGIRLL 212
Query: 193 HKRPDEISQILAQ 205
E IL Q
Sbjct: 213 GTTHAEAMSILKQ 225
Score = 35.8 bits (81), Expect = 0.11
Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 3/89 (3%)
Query: 142 KNKEPLGATIRRDEH---SGAVVVARIMRGGAADRSGLVHVGDELREVNGIAVLHKRPDE 198
K+ LG TI +V++ I +G A R+G + +GD+L ++ I + + ++
Sbjct: 527 KHNVELGITISSPSSRKPGDPLVISDIKKGSVAHRTGTLELGDKLLAIDNIRLDNCSMED 586
Query: 199 ISQILAQSQGSITLKIIPATQEEDRLKES 227
QIL Q + + LKI D + S
Sbjct: 587 AVQILQQCEDLVKLKIRKDEDNSDEQESS 615
Score = 35.0 bits (79), Expect = 0.19
Identities = 25/89 (28%), Positives = 42/89 (47%), Gaps = 4/89 (4%)
Query: 148 GATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIAVLHKRPDEISQILAQSQ 207
G+ + S +++ I A+R G++ +GD + +NGI +E SQ+L S
Sbjct: 437 GSVFATETLSSPPLISYIEADSPAERCGVLQIGDRVMAINGIPTEDSTFEEASQLLRDS- 495
Query: 208 GSITLKIIPATQEEDRLKESKVFMRALFH 236
SIT K+ + E + ES + FH
Sbjct: 496 -SITSKV--TLEIEFDVAESVIPSSGTFH 521
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,127,970
Number of Sequences: 37866
Number of extensions: 1076358
Number of successful extensions: 3468
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 108
Number of HSP's successfully gapped in prelim test: 59
Number of HSP's that attempted gapping in prelim test: 3119
Number of HSP's gapped (non-prelim): 317
length of query: 585
length of database: 18,247,518
effective HSP length: 108
effective length of query: 477
effective length of database: 14,157,990
effective search space: 6753361230
effective search space used: 6753361230
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.