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Search of human proteins with 21361794
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361794 TIP120 protein [Homo sapiens]
(1230 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361794 TIP120 protein [Homo sapiens] 2400 0.0
gi|241982712 TBP-interacting protein isoform 1 [Homo sapiens] 1545 0.0
gi|112420977 TBP-interacting protein isoform 2 [Homo sapiens] 1231 0.0
gi|57863301 CLIP-associating protein 2 [Homo sapiens] 44 0.001
gi|62460637 importin 4 [Homo sapiens] 43 0.002
gi|54607053 GCN1 general control of amino-acid synthesis 1-like ... 41 0.008
gi|11545835 TSPY-like 2 [Homo sapiens] 40 0.010
gi|55956788 nucleolin [Homo sapiens] 40 0.018
gi|214010175 CLIP-associating protein 1 isoform 3 [Homo sapiens] 39 0.040
gi|214010173 CLIP-associating protein 1 isoform 2 [Homo sapiens] 39 0.040
gi|31563537 CLIP-associating protein 1 isoform 1 [Homo sapiens] 39 0.040
gi|23510381 transportin 1 isoform 2 [Homo sapiens] 38 0.052
gi|133925811 transportin 1 isoform 1 [Homo sapiens] 38 0.052
gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens] 38 0.052
gi|50083293 coiled-coil domain containing 123 [Homo sapiens] 38 0.052
gi|22212943 ubiquitin-conjugating enzyme UBC3B [Homo sapiens] 38 0.068
gi|39780552 Vac14 homolog [Homo sapiens] 37 0.12
gi|30089916 phosphofurin acidic cluster sorting protein 1 [Homo ... 37 0.15
gi|42740903 MTERF domain containing 2 [Homo sapiens] 36 0.20
gi|157266317 ataxia telangiectasia and Rad3 related protein [Hom... 36 0.20
gi|169218238 PREDICTED: similar to ataxia telangiectasia and Rad... 36 0.20
gi|115529449 upstream binding transcription factor, RNA polymera... 36 0.20
gi|115529451 upstream binding transcription factor, RNA polymera... 36 0.20
gi|7657671 upstream binding transcription factor, RNA polymerase... 36 0.20
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens] 36 0.26
gi|209969838 transportin 2 (importin 3, karyopherin beta 2b) iso... 36 0.26
gi|209969836 transportin 2 (importin 3, karyopherin beta 2b) iso... 36 0.26
gi|48675813 transportin 2 (importin 3, karyopherin beta 2b) isof... 36 0.26
gi|7661566 integrator complex subunit 7 [Homo sapiens] 36 0.26
gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding pro... 36 0.26
>gi|21361794 TIP120 protein [Homo sapiens]
Length = 1230
Score = 2400 bits (6220), Expect = 0.0
Identities = 1230/1230 (100%), Positives = 1230/1230 (100%)
Query: 1 MASASYHISNLLEKMTSSDKDFRFMATNDLMTELQKDSIKLDDDSERKVVKMILKLLEDK 60
MASASYHISNLLEKMTSSDKDFRFMATNDLMTELQKDSIKLDDDSERKVVKMILKLLEDK
Sbjct: 1 MASASYHISNLLEKMTSSDKDFRFMATNDLMTELQKDSIKLDDDSERKVVKMILKLLEDK 60
Query: 61 NGEVQNLAVKCLGPLVSKVKEYQVETIVDTLCTNMLSDKEQLRDISSIGLKTVIGELPPA 120
NGEVQNLAVKCLGPLVSKVKEYQVETIVDTLCTNMLSDKEQLRDISSIGLKTVIGELPPA
Sbjct: 61 NGEVQNLAVKCLGPLVSKVKEYQVETIVDTLCTNMLSDKEQLRDISSIGLKTVIGELPPA 120
Query: 121 SSGSALAANVCKKITGRLTSAIAKQEDVSVQLEALDIMADMLSRQGGLLVNFHPSILTCL 180
SSGSALAANVCKKITGRLTSAIAKQEDVSVQLEALDIMADMLSRQGGLLVNFHPSILTCL
Sbjct: 121 SSGSALAANVCKKITGRLTSAIAKQEDVSVQLEALDIMADMLSRQGGLLVNFHPSILTCL 180
Query: 181 LPQLTSPRLAVRKRTIIALGHLVMSCGNIVFVDLIEHLLSELSKNDSMSTTRTYIQCIAA 240
LPQLTSPRLAVRKRTIIALGHLVMSCGNIVFVDLIEHLLSELSKNDSMSTTRTYIQCIAA
Sbjct: 181 LPQLTSPRLAVRKRTIIALGHLVMSCGNIVFVDLIEHLLSELSKNDSMSTTRTYIQCIAA 240
Query: 241 ISRQAGHRIGEYLEKIIPLVVKFCNVDDDELREYCIQAFESFVRRCPKEVYPHVSTIINI 300
ISRQAGHRIGEYLEKIIPLVVKFCNVDDDELREYCIQAFESFVRRCPKEVYPHVSTIINI
Sbjct: 241 ISRQAGHRIGEYLEKIIPLVVKFCNVDDDELREYCIQAFESFVRRCPKEVYPHVSTIINI 300
Query: 301 CLKYLTYDPNYNYDDEDEDENAMDADGGDDDDQGSDDEYSDDDDMSWKVRRAAAKCLDAV 360
CLKYLTYDPNYNYDDEDEDENAMDADGGDDDDQGSDDEYSDDDDMSWKVRRAAAKCLDAV
Sbjct: 301 CLKYLTYDPNYNYDDEDEDENAMDADGGDDDDQGSDDEYSDDDDMSWKVRRAAAKCLDAV 360
Query: 361 VSTRHEMLPEFYKTVSPALISRFKEREENVKADVFHAYLSLLKQTRPVQSWLCDPDAMEQ 420
VSTRHEMLPEFYKTVSPALISRFKEREENVKADVFHAYLSLLKQTRPVQSWLCDPDAMEQ
Sbjct: 361 VSTRHEMLPEFYKTVSPALISRFKEREENVKADVFHAYLSLLKQTRPVQSWLCDPDAMEQ 420
Query: 421 GETPLTMLQSQVPNIVKALHKQMKEKSVKTRQCCFNMLTELVNVLPGALTQHIPVLVPGI 480
GETPLTMLQSQVPNIVKALHKQMKEKSVKTRQCCFNMLTELVNVLPGALTQHIPVLVPGI
Sbjct: 421 GETPLTMLQSQVPNIVKALHKQMKEKSVKTRQCCFNMLTELVNVLPGALTQHIPVLVPGI 480
Query: 481 IFSLNDKSSSSNLKIDALSCLYVILCNHSPQVFHPHVQALVPPVVACVGDPFYKITSEAL 540
IFSLNDKSSSSNLKIDALSCLYVILCNHSPQVFHPHVQALVPPVVACVGDPFYKITSEAL
Sbjct: 481 IFSLNDKSSSSNLKIDALSCLYVILCNHSPQVFHPHVQALVPPVVACVGDPFYKITSEAL 540
Query: 541 LVTQQLVKVIRPLDQPSSFDATPYIKDLFTCTIKRLKAADIDQEVKERAISCMGQIICNL 600
LVTQQLVKVIRPLDQPSSFDATPYIKDLFTCTIKRLKAADIDQEVKERAISCMGQIICNL
Sbjct: 541 LVTQQLVKVIRPLDQPSSFDATPYIKDLFTCTIKRLKAADIDQEVKERAISCMGQIICNL 600
Query: 601 GDNLGSDLPNTLQIFLERLKNEITRLTTVKALTLIAGSPLKIDLRPVLGEGVPILASFLR 660
GDNLGSDLPNTLQIFLERLKNEITRLTTVKALTLIAGSPLKIDLRPVLGEGVPILASFLR
Sbjct: 601 GDNLGSDLPNTLQIFLERLKNEITRLTTVKALTLIAGSPLKIDLRPVLGEGVPILASFLR 660
Query: 661 KNQRALKLGTLSALDILIKNYSDSLTAAMIDAVLDELPPLISESDMHVSQMAISFLTTLA 720
KNQRALKLGTLSALDILIKNYSDSLTAAMIDAVLDELPPLISESDMHVSQMAISFLTTLA
Sbjct: 661 KNQRALKLGTLSALDILIKNYSDSLTAAMIDAVLDELPPLISESDMHVSQMAISFLTTLA 720
Query: 721 KVYPSSLSKISGSILNELIGLVRSPLLQGGALSAMLDFFQALVVTGTNNLGYMDLLRMLT 780
KVYPSSLSKISGSILNELIGLVRSPLLQGGALSAMLDFFQALVVTGTNNLGYMDLLRMLT
Sbjct: 721 KVYPSSLSKISGSILNELIGLVRSPLLQGGALSAMLDFFQALVVTGTNNLGYMDLLRMLT 780
Query: 781 GPVYSQSTALTHKQSYYSIAKCVAALTRACPKEGPAVVGQFIQDVKNSRSTDSIRLLALL 840
GPVYSQSTALTHKQSYYSIAKCVAALTRACPKEGPAVVGQFIQDVKNSRSTDSIRLLALL
Sbjct: 781 GPVYSQSTALTHKQSYYSIAKCVAALTRACPKEGPAVVGQFIQDVKNSRSTDSIRLLALL 840
Query: 841 SLGEVGHHIDLSGQLELKSVILEAFSSPSEEVKSAASYALGSISVGNLPEYLPFVLQEIT 900
SLGEVGHHIDLSGQLELKSVILEAFSSPSEEVKSAASYALGSISVGNLPEYLPFVLQEIT
Sbjct: 841 SLGEVGHHIDLSGQLELKSVILEAFSSPSEEVKSAASYALGSISVGNLPEYLPFVLQEIT 900
Query: 901 SQPKRQYLLLHSLKEIISSASVVGLKPYVENIWALLLKHCECAEEGTRNVVAECLGKLTL 960
SQPKRQYLLLHSLKEIISSASVVGLKPYVENIWALLLKHCECAEEGTRNVVAECLGKLTL
Sbjct: 901 SQPKRQYLLLHSLKEIISSASVVGLKPYVENIWALLLKHCECAEEGTRNVVAECLGKLTL 960
Query: 961 IDPETLLPRLKGYLISGSSYARSSVVTAVKFTISDHPQPIDPLLKNCIGDFLKTLEDPDL 1020
IDPETLLPRLKGYLISGSSYARSSVVTAVKFTISDHPQPIDPLLKNCIGDFLKTLEDPDL
Sbjct: 961 IDPETLLPRLKGYLISGSSYARSSVVTAVKFTISDHPQPIDPLLKNCIGDFLKTLEDPDL 1020
Query: 1021 NVRRVALVTFNSAAHNKPSLIRDLLDTVLPHLYNETKVRKELIREVEMGPFKHTVDDGLD 1080
NVRRVALVTFNSAAHNKPSLIRDLLDTVLPHLYNETKVRKELIREVEMGPFKHTVDDGLD
Sbjct: 1021 NVRRVALVTFNSAAHNKPSLIRDLLDTVLPHLYNETKVRKELIREVEMGPFKHTVDDGLD 1080
Query: 1081 IRKAAFECMYTLLDSCLDRLDIFEFLNHVEDGLKDHYDIKMLTFLMLVRLSTLCPSAVLQ 1140
IRKAAFECMYTLLDSCLDRLDIFEFLNHVEDGLKDHYDIKMLTFLMLVRLSTLCPSAVLQ
Sbjct: 1081 IRKAAFECMYTLLDSCLDRLDIFEFLNHVEDGLKDHYDIKMLTFLMLVRLSTLCPSAVLQ 1140
Query: 1141 RLDRLVEPLRATCTTKVKANSVKQEFEKQDELKRSAMRAVAALLTIPEAEKSPLMSEFQS 1200
RLDRLVEPLRATCTTKVKANSVKQEFEKQDELKRSAMRAVAALLTIPEAEKSPLMSEFQS
Sbjct: 1141 RLDRLVEPLRATCTTKVKANSVKQEFEKQDELKRSAMRAVAALLTIPEAEKSPLMSEFQS 1200
Query: 1201 QISSNPELAAIFESIQKDSSSTNLESMDTS 1230
QISSNPELAAIFESIQKDSSSTNLESMDTS
Sbjct: 1201 QISSNPELAAIFESIQKDSSSTNLESMDTS 1230
>gi|241982712 TBP-interacting protein isoform 1 [Homo sapiens]
Length = 1236
Score = 1545 bits (4001), Expect = 0.0
Identities = 772/1237 (62%), Positives = 988/1237 (79%), Gaps = 8/1237 (0%)
Query: 1 MASASYHISNLLEKMTSSDKDFRFMATNDLMTELQKDSIKLDDDSERKVVKMILKLLEDK 60
M++A++HIS+LLEKMTSSDKDFRFMAT+DLM+ELQKDSI+LD+DSERKVVKM+L+LLEDK
Sbjct: 1 MSTAAFHISSLLEKMTSSDKDFRFMATSDLMSELQKDSIQLDEDSERKVVKMLLRLLEDK 60
Query: 61 NGEVQNLAVKCLGPLVSKVKEYQVETIVDTLCTNMLSDKEQLRDISSIGLKTVIGELPPA 120
NGEVQNLAVKCLGPLV KVKEYQVETIVDTLCTNM SDKEQLRDI+ IGLKTV+ ELPPA
Sbjct: 61 NGEVQNLAVKCLGPLVVKVKEYQVETIVDTLCTNMRSDKEQLRDIAGIGLKTVLSELPPA 120
Query: 121 SSGSALAANVCKKITGRLTSAIAKQEDVSVQLEALDIMADMLSRQGGLLVNFHPSILTCL 180
++GS LA NVC+KITG+LTSAIA+QEDV+VQLEALDI++DMLSR G L FH S+L CL
Sbjct: 121 ATGSGLATNVCRKITGQLTSAIAQQEDVAVQLEALDILSDMLSRLGVPLGAFHASLLHCL 180
Query: 181 LPQLTSPRLAVRKRTIIALGHLVMSCGNIVFVDLIEHLLSELSKN---DSMSTTRTYIQC 237
LPQL+SPRLAVRKR + ALGHL +C +FV+L +HLL L S + RT IQC
Sbjct: 181 LPQLSSPRLAVRKRAVGALGHLAAACSTDLFVELADHLLDRLPGPRVPTSPTAIRTLIQC 240
Query: 238 IAAISRQAGHRIGEYLEKIIPLVVKFCNVDDDELREYCIQAFESFVRRCPKEVYPHVSTI 297
+ ++ RQAGHR+G +L++++PLV FCN+DDDELRE C+QAFE+F+R+CPKE+ PHV +
Sbjct: 241 LGSVGRQAGHRLGAHLDRLVPLVEDFCNLDDDELRESCLQAFEAFLRKCPKEMGPHVPNV 300
Query: 298 INICLKYLTYDPNYNYDDEDEDENAMDADGGDDDDQGSDDEYSDDDDMSWKVRRAAAKCL 357
++CL+Y+ +DPNYNYD DEDE M+ + + +Q S+DEYSDDDDMSWKVRRAAAKC+
Sbjct: 301 TSLCLQYIKHDPNYNYDS-DEDEEQMETEDSEFSEQESEDEYSDDDDMSWKVRRAAAKCI 359
Query: 358 DAVVSTRHEMLPEFYKTVSPALISRFKEREENVKADVFHAYLSLLKQTRPVQSWLCDPDA 417
A++S+R ++LP+F+ T++P LI RFKEREENVKADVF AY+ LL+QT+P + WL +
Sbjct: 360 AALISSRPDLLPDFHCTLAPVLIRRFKEREENVKADVFTAYIVLLRQTQPPKGWLEAMEE 419
Query: 418 MEQGETPLTMLQSQVPNIVKALHKQMKEKSVKTRQCCFNMLTELVNVLPGALTQHIPVLV 477
Q + L ML+ QVP +VKAL +Q+K++SV+ RQ CF++LTEL VLPG+L +H+PVLV
Sbjct: 420 PTQTGSNLHMLRGQVPLVVKALQRQLKDRSVRARQGCFSLLTELAGVLPGSLAEHMPVLV 479
Query: 478 PGIIFSLNDKSSSSNLKIDALSCLYVILCNHSPQVFHPHVQALVPPVVACVGDPFYKITS 537
GIIFSL D+SSSS +++DAL+ L +L + FHPH+ L+PPV+ACV D FYKI +
Sbjct: 480 SGIIFSLADRSSSSTIRMDALAFLQGLLGTEPAEAFHPHLPILLPPVMACVADSFYKIAA 539
Query: 538 EALLVTQQLVKVIRPLDQPSSFDATPYIKDLFTCTIKRLKAADIDQEVKERAISCMGQII 597
EAL+V Q+LV+ + PL +P D PY+ ++ T+ RL+A D+DQEVKERAISCMG ++
Sbjct: 540 EALVVLQELVRALWPLHRPRMLDPEPYVGEMSAVTLARLRATDLDQEVKERAISCMGHLV 599
Query: 598 CNLGDNLGSDLPNTLQIFLERLKNEITRLTTVKALTLIAGSPLKIDLRPVLGEGVPILAS 657
+LGD LG DL TL + L+RL+NEITRL +KALTL+A SPL++DL+P+L E + ILAS
Sbjct: 600 GHLGDRLGDDLEPTLLLLLDRLRNEITRLPAIKALTLVAVSPLQLDLQPILAEALHILAS 659
Query: 658 FLRKNQRALKLGTLSALDILIKNYSDSLTAAMIDAVLDELPPLISESDMHVSQMAISFLT 717
FLRKNQRAL+L TL+ALD L ++ SL + + AVL ELP L++ESDMHV+Q+A+ FL
Sbjct: 660 FLRKNQRALRLATLAALDALAQSQGLSLPPSAVQAVLAELPALVNESDMHVAQLAVDFLA 719
Query: 718 TLAKVYPSSLSKISGSILNELIGLVRSPLLQGGALSAMLDFFQALVVTGTNNLGYMDLLR 777
T+ + P+SL ++SG +L+EL+ L+RSPLL G L+A F QALV T + Y L+
Sbjct: 720 TVTQAQPASLVEVSGPVLSELLRLLRSPLLPAGVLAAAEGFLQALVGTRPPCVDYAKLIS 779
Query: 778 MLTGPVYSQST---ALTHKQSYYSIAKCVAALTRACPKEGPAVVGQFIQDVKNSRSTDSI 834
+LT PVY Q+ HKQ ++S+A+CVAAL+ ACP+E + + + D ++ S+ +
Sbjct: 780 LLTAPVYEQAVDGGPGLHKQVFHSLARCVAALSAACPQEAASTASRLVCDARSPHSSTGV 839
Query: 835 RLLALLSLGEVGHHIDLSGQLELKSVILEAFSSPSEEVKSAASYALGSISVGNLPEYLPF 894
++LA LSL EVG Q ELK+V+LEA SPSE+V++AASYALG + G+LP++LPF
Sbjct: 840 KVLAFLSLAEVGQVAGPGHQRELKAVLLEALGSPSEDVRAAASYALGRVGAGSLPDFLPF 899
Query: 895 VLQEITSQPKRQYLLLHSLKEIISSASVVGLKPYVENIWALLLKHCECAEEGTRNVVAEC 954
+L++I ++P+RQYLLLHSL+E + +A LKPY E+IWALL + CE AEEGTR VVAEC
Sbjct: 900 LLEQIEAEPRRQYLLLHSLREALGAAQPDSLKPYAEDIWALLFQRCEGAEEGTRGVVAEC 959
Query: 955 LGKLTLIDPETLLPRLKGYLISGSSYARSSVVTAVKFTISDHPQPIDPLLKNCIGDFLKT 1014
+GKL L++P LLPRL+ L +G + RS+V+TAVKF ISD P PIDPLLK+ IG+F+++
Sbjct: 960 IGKLVLVNPSFLLPRLRKQLAAGRPHTRSTVITAVKFLISDQPHPIDPLLKSFIGEFMES 1019
Query: 1015 LEDPDLNVRRVALVTFNSAAHNKPSLIRDLLDTVLPHLYNETKVRKELIREVEMGPFKHT 1074
L+DPDLNVRR L FNSA HNKPSL+RDLLD +LP LY ETK+R++LIREVEMGPFKHT
Sbjct: 1020 LQDPDLNVRRATLAFFNSAVHNKPSLVRDLLDDILPLLYQETKIRRDLIREVEMGPFKHT 1079
Query: 1075 VDDGLDIRKAAFECMYTLLDSCLDRLDIFEFLNHVEDGLKDHYDIKMLTFLMLVRLSTLC 1134
VDDGLD+RKAAFECMY+LL+SCL +LDI EFLNHVEDGLKDHYDI+MLTF+M+ RL+TLC
Sbjct: 1080 VDDGLDVRKAAFECMYSLLESCLGQLDICEFLNHVEDGLKDHYDIRMLTFIMVARLATLC 1139
Query: 1135 PSAVLQRLDRLVEPLRATCTTKVKANSVKQEFEKQDELKRSAMRAVAALLTIPEAEKSPL 1194
P+ VLQR+DRL+EPLRATCT KVKA SVKQEFEKQDELKRSAMRAVAALLTIPE KSP+
Sbjct: 1140 PAPVLQRVDRLIEPLRATCTAKVKAGSVKQEFEKQDELKRSAMRAVAALLTIPEVGKSPI 1199
Query: 1195 MSEFQSQISSNPELAAIFESIQKDSSST-NLESMDTS 1230
M++F SQI SNPELAA+FESIQKDS+S + +SM+ S
Sbjct: 1200 MADFSSQIRSNPELAALFESIQKDSASAPSTDSMELS 1236
>gi|112420977 TBP-interacting protein isoform 2 [Homo sapiens]
Length = 1119
Score = 1231 bits (3184), Expect = 0.0
Identities = 618/1066 (57%), Positives = 808/1066 (75%), Gaps = 32/1066 (3%)
Query: 172 FHPSILTCLLPQLTSPRLAVRKRTIIALGHLVMSCGNIVFVDLIEHLLSELSKN---DSM 228
FH S+L CLLPQL+SPRLAVRKR + ALGHL +C +FV+L +HLL L S
Sbjct: 79 FHASLLHCLLPQLSSPRLAVRKRAVGALGHLAAACSTDLFVELADHLLDRLPGPRVPTSP 138
Query: 229 STTRTYIQCIAAISRQAGHRIGEYLEKIIPLVVKFCNVDDDELREYCIQAFESFVRRCPK 288
+ RT IQC+ ++ RQAGHR+G +L++++PLV FCN+DDDELRE C+QAFE+F+R+CPK
Sbjct: 139 TAIRTLIQCLGSVGRQAGHRLGAHLDRLVPLVEDFCNLDDDELRESCLQAFEAFLRKCPK 198
Query: 289 EVYPHVSTIINICLKYLTYDPNYNYDDEDEDENAMDADGGDDDDQGSDDEYSDDDDMSWK 348
E+ PHV + ++CL+Y+ +DPNYNYD DEDE M+ + + +Q S+DEYSDDDDMSWK
Sbjct: 199 EMGPHVPNVTSLCLQYIKHDPNYNYDS-DEDEEQMETEDSEFSEQESEDEYSDDDDMSWK 257
Query: 349 VRRAAAKCLDAVVSTRHEMLPEFYKTVSPALISRFKEREENVKADVFHAYLSLLKQTRPV 408
VRRAAAKC+ A++S+R ++LP+F+ T++P LI RFKEREENVKADVF AY+ LL+QT+P
Sbjct: 258 VRRAAAKCIAALISSRPDLLPDFHCTLAPVLIRRFKEREENVKADVFTAYIVLLRQTQPP 317
Query: 409 QSWLCDPDAMEQGETPLTMLQSQVPNIVKALHKQMKEKSVKTRQCCFNMLTELVNVLPGA 468
+ WL + Q + L ML+ QVP +VKAL +Q+K++SV+ RQ CF++LTEL VLPG+
Sbjct: 318 KGWLEAMEEPTQTGSNLHMLRGQVPLVVKALQRQLKDRSVRARQGCFSLLTELAGVLPGS 377
Query: 469 LTQHIPVLVPGIIFSLNDKSSSSNLKIDALSCLYVILCNHSPQVFHPHVQALVPPVVACV 528
L +H+PVLV GIIFSL D+SSSS +++DAL+ L +L + FHPH+ L+PPV+ACV
Sbjct: 378 LAEHMPVLVSGIIFSLADRSSSSTIRMDALAFLQGLLGTEPAEAFHPHLPILLPPVMACV 437
Query: 529 GDPFYKITSEALLVTQQLVKVIRPLDQPSSFDATPYIKDLFTCTIKRLKAADIDQEVKER 588
D FYKI +EAL+V Q+LV+ + PL +P D PY+ ++ T+ RL+A D+DQEVKER
Sbjct: 438 ADSFYKIAAEALVVLQELVRALWPLHRPRMLDPEPYVGEMSAVTLARLRATDLDQEVKER 497
Query: 589 AISCMGQIICNLGDNLGSDLPNTLQIFLERLKNEITRLTTVKALTLIAGSPLKIDLRPVL 648
AISCMG ++ +LGD LG DL TL + L+RL+NEITRL +KALTL+A SPL++DL+P+L
Sbjct: 498 AISCMGHLVGHLGDRLGDDLEPTLLLLLDRLRNEITRLPAIKALTLVAVSPLQLDLQPIL 557
Query: 649 GEGVPILASFLRKNQRALKLGTLSALDILIKNYSDSLTAAMIDAVLDELPPLISESDMHV 708
E + ILASFLRKNQRAL+L TL+ALD L ++ SL + + AVL ELP L++ESDMHV
Sbjct: 558 AEALHILASFLRKNQRALRLATLAALDALAQSQGLSLPPSAVQAVLAELPALVNESDMHV 617
Query: 709 SQMAISFLTTLAKVYPSSLSKISGSILNELIGLVRSPLLQGGALSAMLDFFQALVVTGTN 768
+Q+A+ FL T+ + P+SL ++SG +L+EL+ L+RSPLL G L+A F QALV T
Sbjct: 618 AQLAVDFLATVTQAQPASLVEVSGPVLSELLRLLRSPLLPAGVLAAAEGFLQALVGTRPP 677
Query: 769 NLGYMDLLRMLTGPVYSQST---ALTHKQSYYSIAKCVAALTRACPKEGPAVVGQFIQDV 825
+ Y L+ +LT PVY Q+ HKQ ++S+A+CVAAL+ ACP+E + + + D
Sbjct: 678 CVDYAKLISLLTAPVYEQAVDGGPGLHKQVFHSLARCVAALSAACPQEAASTASRLVCDA 737
Query: 826 KNSRSTDSIRLLALLSLGEVGHHIDLSGQLELKSVILEAFSSPSEEVKSAASYALGSISV 885
++ S+ +++LA LSL EVG Q ELK+V+LEA SPSE+V++AASYALG +
Sbjct: 738 RSPHSSTGVKVLAFLSLAEVGQVAGPGHQRELKAVLLEALGSPSEDVRAAASYALGRVGA 797
Query: 886 GNLPEYLPFVLQEITSQPKRQYLLLHSLKEIISSASVVGLKPYVENIWALLLKHCECAEE 945
G+LP++LPF+L++I ++P+RQYLLLHSL+E + +A LKPY E+IWALL + CE AEE
Sbjct: 798 GSLPDFLPFLLEQIEAEPRRQYLLLHSLREALGAAQPDSLKPYAEDIWALLFQRCEGAEE 857
Query: 946 GTRNVVAECLGKLTLIDPETLLPRLKGYLISGSSYARSSVVTAVKFTISDHPQPIDPLLK 1005
GTR VVAEC+GKL L++P LLPRL+ L +G + RS+V+TAVKF ISD P PIDPLLK
Sbjct: 858 GTRGVVAECIGKLVLVNPSFLLPRLRKQLAAGRPHTRSTVITAVKFLISDQPHPIDPLLK 917
Query: 1006 NCIGDFLKTLEDPDLNVRRVALVTFNSAAHNKPSLIRDLLDTVLPHLYNETKVRKELIRE 1065
+ I A HNKPSL+RDLLD +LP LY ETK+R++LIRE
Sbjct: 918 SFI------------------------AVHNKPSLVRDLLDDILPLLYQETKIRRDLIRE 953
Query: 1066 VEMGPFKHTVDDGLDIRKAAFECMYTLLDSCLDRLDIFEFLNHVEDGLKDHYDIKMLTFL 1125
VEMGPFKHTVDDGLD+RKAAFECMY+LL+SCL +LDI EFLNHVEDGLKDHYDI+MLTF+
Sbjct: 954 VEMGPFKHTVDDGLDVRKAAFECMYSLLESCLGQLDICEFLNHVEDGLKDHYDIRMLTFI 1013
Query: 1126 MLVRLSTLCPSAVLQRLDRLVEPLRATCTTKVKANSVKQEFEKQDELKRSAMRAVAALLT 1185
M+ RL+TLCP+ VLQR+DRL+EPLRATCT KVKA SVKQEFEKQDELKRSAMRAVAALLT
Sbjct: 1014 MVARLATLCPAPVLQRVDRLIEPLRATCTAKVKAGSVKQEFEKQDELKRSAMRAVAALLT 1073
Query: 1186 IPEAEKSPLMSEFQSQISSNPELAAIFESIQKDSSST-NLESMDTS 1230
IPE KSP+M++F SQI SNPELAA+FESIQKDS+S + +SM+ S
Sbjct: 1074 IPEVGKSPIMADFSSQIRSNPELAALFESIQKDSASAPSTDSMELS 1119
>gi|57863301 CLIP-associating protein 2 [Homo sapiens]
Length = 1506
Score = 43.5 bits (101), Expect = 0.001
Identities = 41/199 (20%), Positives = 92/199 (46%), Gaps = 21/199 (10%)
Query: 8 ISNLLEKMTSSDK--DFRFMATNDLMTELQKDSIKLDDDSERKVVKMILKLLEDKNGEVQ 65
++ LL+++++ ++ + R +A +LM Q++S + D+ + ++ ++L+ L DK ++
Sbjct: 1272 VAELLKELSNHNERVEERKIALYELMKLTQEESFSVWDEHFKTILLLLLETLGDKEPTIR 1331
Query: 66 NLAVKCLGPLV----SKVKEYQVETIVDTLCTNMLSDKEQLRDISSIGLKTVIGELPPAS 121
LA+K L ++ ++ K Y T++ TL + KE +R
Sbjct: 1332 ALALKVLREILRHQPARFKNYAELTVMKTLEAHKDPHKEVVRSAE--------------E 1377
Query: 122 SGSALAANVCKKITGRLTSAIAKQEDVSVQLEALDIMADMLSRQGGLLVN-FHPSILTCL 180
+ S LA ++ + ++ I + D + L A+ + ++ R +N P I+ L
Sbjct: 1378 AASVLATSISPEQCIKVLCPIIQTADYPINLAAIKMQTKVIERVSKETLNLLLPEIMPGL 1437
Query: 181 LPQLTSPRLAVRKRTIIAL 199
+ + +VRK + L
Sbjct: 1438 IQGYDNSESSVRKACVFCL 1456
>gi|62460637 importin 4 [Homo sapiens]
Length = 1081
Score = 43.1 bits (100), Expect = 0.002
Identities = 66/319 (20%), Positives = 128/319 (40%), Gaps = 41/319 (12%)
Query: 36 KDSIKLDDDSERKVVKMILKLLEDKNGEVQNLAVKCLGPLVSKVKEYQVETIVDTLCTNM 95
+++++ + +RK ++L +L D G+ ++ + L PL+ V C +
Sbjct: 358 EEALRSESPYQRKAGLLVLAVLSDGAGD--HIRQRLLPPLLQIV------------CKGL 403
Query: 96 LSDKEQLRDISSIGLKTVIGELPPASSGSALAANVCKKITGRLTSA-IAKQEDVSVQLEA 154
+ +R+ + L L P S + + V + L S + ++ A
Sbjct: 404 EDPSQVVRNAALFALGQFSENLQPHIS--SYSREVMPLLLAYLKSVPLGHTHHLAKACYA 461
Query: 155 LDIMADMLSRQGGLLVNFHPSILTCLLPQLTSPRLAVRKRTII-ALGHLVMSCGNIV--- 210
L+ + L G + + P ++ C+L L +P K + ALG + + +
Sbjct: 462 LENFVENL---GPKVQPYLPELMECMLQLLRNPSSPRAKELAVSALGAIATAAQASLLPY 518
Query: 211 FVDLIEHLLSEL--SKNDSMSTTRTYIQCIAAISRQAGHRIGEYLEKIIPLVVKFCN-VD 267
F ++EHL L + D ++ + ++R G + E+ L + C+ VD
Sbjct: 519 FPAIMEHLREFLLTGREDLQPVQIQSLETLGVLARAVGEPMRPLAEECCQLGLGLCDQVD 578
Query: 268 DDELREYCIQAFESFVRRCPKEVYPHVSTIINICLKYLTYD----PNYN-------YDDE 316
D +LR F + + + PH+ I + L L P Y+ +DDE
Sbjct: 579 DPDLRRCTYSLFAALSGLMGEGLAPHLEQITTLMLLSLRSTEGIVPQYDGSSSFLLFDDE 638
Query: 317 ---DEDENAMDADGGDDDD 332
+E+E MD D ++DD
Sbjct: 639 SDGEEEEELMDEDVEEEDD 657
Score = 33.9 bits (76), Expect = 0.98
Identities = 55/245 (22%), Positives = 96/245 (39%), Gaps = 42/245 (17%)
Query: 808 RACPKEGPAVVGQFIQDVKNSRSTDSIRLLALLSLGEVGHHIDLSGQLELKSVILEAFSS 867
+ CP+ P + + R + +LA+LS G G HI L ++ +
Sbjct: 348 KLCPQLMPMLEEALRSESPYQRKA-GLLVLAVLSDG-AGDHIRQRLLPPLLQIVCKGLED 405
Query: 868 PSEEVKSAASYALGSISVGNLP-------EYLPFVLQEITSQPKRQYLLLHSLKEIISSA 920
PS+ V++AA +ALG S P E +P +L + S P H L +
Sbjct: 406 PSQVVRNAALFALGQFSENLQPHISSYSREVMPLLLAYLKSVPLGH---THHL-----AK 457
Query: 921 SVVGLKPYVEN----IWALLLKHCECAEEGTRN--------VVAECLGKLTLIDPETLLP 968
+ L+ +VEN + L + EC + RN + LG + +LLP
Sbjct: 458 ACYALENFVENLGPKVQPYLPELMECMLQLLRNPSSPRAKELAVSALGAIATAAQASLLP 517
Query: 969 -------RLKGYLISGSSYARSSVVTAVK---FTISDHPQPIDPLLKNCIG---DFLKTL 1015
L+ +L++G + + +++ +P+ PL + C +
Sbjct: 518 YFPAIMEHLREFLLTGREDLQPVQIQSLETLGVLARAVGEPMRPLAEECCQLGLGLCDQV 577
Query: 1016 EDPDL 1020
+DPDL
Sbjct: 578 DDPDL 582
>gi|54607053 GCN1 general control of amino-acid synthesis 1-like 1
[Homo sapiens]
Length = 2671
Score = 40.8 bits (94), Expect = 0.008
Identities = 58/268 (21%), Positives = 98/268 (36%), Gaps = 13/268 (4%)
Query: 49 VVKMILKLLEDKNGEVQNLAVKCLGPLVSKVKEYQVETIVDTLCTNMLSDKEQLRDISSI 108
+V + ++L D + +VQ + L + S ++ ++ I L + + +
Sbjct: 1539 IVPKLTEVLTDSHVKVQKAGQQALRQIGSVIRNPEILAIAPVLLDALTDPSRKTQKCLQT 1598
Query: 109 GLKTVIGELPPASSGSALAANVCKKITGRLTSAIAKQEDVSVQLEALDIMADMLSRQGGL 168
L T A S + + V + R T + + +L D
Sbjct: 1599 LLDTKFVHFIDAPSLALIMPIVQRAFQDRSTDTRKMAAQIIGNMYSLTDQKD-------- 1650
Query: 169 LVNFHPSILTCLLPQLTSPRLAVRKRTIIALGHLVMSCGNIVFVDLIEHLLSELSKNDSM 228
L + PS+ L L P VR + ALG +V G F DL+ L+ L+ S
Sbjct: 1651 LAPYLPSVTPGLKASLLDPVPEVRTVSAKALGAMVKGMGESCFEDLLPWLMETLTYEQSS 1710
Query: 229 STTRTYIQCIAAISRQAGHRIGEYLEKIIPLVVKFCNVDD--DELREYCIQAFESFVRRC 286
Q +A + G E LEK++P +V + D +R+ I F
Sbjct: 1711 VDRSGAAQGLAEVMAGLG---VEKLEKLMPEIVATASKVDIAPHVRDGYIMMFNYLPITF 1767
Query: 287 PKEVYPHVSTIINICLKYLTYDPNYNYD 314
+ P+V II LK L + + D
Sbjct: 1768 GDKFTPYVGPIIPCILKALADENEFVRD 1795
Score = 40.4 bits (93), Expect = 0.010
Identities = 153/763 (20%), Positives = 283/763 (37%), Gaps = 187/763 (24%)
Query: 49 VVKMILKLLEDKNGEVQNLAVKCLGPLVSKVKEYQVETIVDTLCTNMLSDKEQLRDISSI 108
++ ILK L D+N V++ A++ ++S E + ++ L + D ++R SS+
Sbjct: 1778 IIPCILKALADENEFVRDTALRAGQRVISMYAETAIALLLPQLEQGLFDDLWRIR-FSSV 1836
Query: 109 GLKTVIGELPPASSGSALAANVCKKITGRLTSAIAKQEDV-------SVQLEALDIM--- 158
L +G+L SG +TG++T+ A ++D + AL +
Sbjct: 1837 QL---LGDLLFHISG----------VTGKMTTETASEDDNFGTAQSNKAIITALGVERRN 1883
Query: 159 ------------ADMLSRQGGL-----LVNFHPSILTCLLPQLTSPRLA------VRKRT 195
++ RQ L +V+ P L +LP L L KRT
Sbjct: 1884 RVLAGLYMGRSDTQLVVRQASLHVWKIVVSNTPRTLREILPTLFGLLLGFLASTCADKRT 1943
Query: 196 IIA--LGHLVMSCGNIVFVDLIEHL------------------LSELSKNDSMSTTRTYI 235
I A LG LV G + ++I L LSE+ K+ S +
Sbjct: 1944 IAARTLGDLVRKLGEKILPEIIPILEEGLRSQKSDERQGVCIGLSEIMKSTSRDAVLYFS 2003
Query: 236 QCIAAISRQA-----------------------GHRIGEYLEKIIPLVVKFCNVDDDELR 272
+ + +R+A GH+ LE I+P ++K +DD+E+
Sbjct: 2004 ESLVPTARKALCDPLEEVREAAAKTFEQLHSTIGHQA---LEDILPFLLK--QLDDEEVS 2058
Query: 273 EYCIQAFESFVR---------RCPKEVYPHVSTIINICLKYLTYDPNYNY---------- 313
E+ + + + PK P V+T + L + D +
Sbjct: 2059 EFALDGLKQVMAIKSRVVLPYLVPKLTTPPVNTRVLAFLSSVAGDALTRHLGVILPAVML 2118
Query: 314 ---------DDEDEDENAMDADGGDDDDQGS----DDEYSDDDDMSWKVRRAAAKCLDAV 360
D++ E N +DD G +D +R+AAA L+
Sbjct: 2119 ALKEKLGTPDEQLEMANCQAVILSVEDDTGHRIIIEDLLEATRSPEVGMRQAAAIILNIY 2178
Query: 361 VSTRHEMLPEFYKTVSPALISRFKEREENVKADVFHAYLSLLKQTRPVQSWLCDPDAMEQ 420
S +++ LI F + V + + A ++ K+ DA Q
Sbjct: 2179 CSRSKADYTSHLRSLVSGLIRLFNDSSPVVLEESWDALNAITKKL----------DAGNQ 2228
Query: 421 GETPLTMLQSQVPNIVKALHKQMKEKSVKTRQCCFNMLTELVNVLPG------ALTQHIP 474
+++ LHK+++ +++ +PG +T +P
Sbjct: 2229 LA------------LIEELHKEIRLIGNESKG----------EHVPGFCLPKKGVTSILP 2266
Query: 475 VLVPGIIFSLNDKSSSSNLKIDALSCLYVILCNHSPQVFHPHVQALVPPVVACVGDPFYK 534
VL G++ + S K +A L +++ S P V ++ P++ +GD F
Sbjct: 2267 VLREGVL------TGSPEQKEEAAKALGLVIRLTSADALRPSVVSITGPLIRILGDRFSW 2320
Query: 535 ITSEALLVTQQLVKVIRPLDQPSSFDATPYIKDLFTCTIKRLKAADIDQEVKERAISCMG 594
ALL T L L P++ L T K L+ D ++ V+ +A +G
Sbjct: 2321 NVKAALLETLSL------LLAKVGIALKPFLPQLQTTFTKALQ--DSNRGVRLKAADALG 2372
Query: 595 QIIC--NLGDNLGSDLPNTLQIFLERLKNEITRLTTVKALT-LIAGSPLKIDLRPVLGEG 651
++I D L ++L N ++ +++ R T ++AL +I G+ K+D +
Sbjct: 2373 KLISIHIKVDPLFTELLNGIR----AMEDPGVRDTMLQALRFVIQGAGAKVD-AVIRKNI 2427
Query: 652 VPILASFLRKNQRALKLGTLSALDILIKNYSDSLTAAMIDAVL 694
V +L S L ++ ++ + L L ++ +A++ L
Sbjct: 2428 VSLLLSMLGHDEDNTRISSAGCLGELCAFLTEEELSAVLQQCL 2470
Score = 37.0 bits (84), Expect = 0.12
Identities = 51/207 (24%), Positives = 82/207 (39%), Gaps = 19/207 (9%)
Query: 834 IRLLALLSLGE--VGHHIDLSGQLELKSVILEAFSSPSEEVKSAASYALGSISVGNLPEY 891
IRL+ S GE G + G + V+ E + S E K A+ ALG + +
Sbjct: 2239 IRLIGNESKGEHVPGFCLPKKGVTSILPVLREGVLTGSPEQKEEAAKALGLVIRLTSADA 2298
Query: 892 LPFVLQEITSQPKR----------QYLLLHSLKEIISSASVVGLKPYVENIWALLLKHCE 941
L + IT R + LL +L +++ + LKP++ + K +
Sbjct: 2299 LRPSVVSITGPLIRILGDRFSWNVKAALLETLSLLLAKVGIA-LKPFLPQLQTTFTKALQ 2357
Query: 942 CAEEGTRNVVAECLGKLTLI----DPETLLPRLKGYLISGSSYARSSVVTAVKFTISDHP 997
+ G R A+ LGKL I DP L G R +++ A++F I
Sbjct: 2358 DSNRGVRLKAADALGKLISIHIKVDP-LFTELLNGIRAMEDPGVRDTMLQALRFVIQGAG 2416
Query: 998 QPIDPLL-KNCIGDFLKTLEDPDLNVR 1023
+D ++ KN + L L + N R
Sbjct: 2417 AKVDAVIRKNIVSLLLSMLGHDEDNTR 2443
Score = 34.3 bits (77), Expect = 0.75
Identities = 66/304 (21%), Positives = 119/304 (39%), Gaps = 21/304 (6%)
Query: 13 EKMTSSDKDFRFMATNDLMTELQKDSIKLDDDSERKVVKMILKL---LEDKNGEVQNLAV 69
E + ++ D + A + L K D S+ KV ++ KL L + +VQ
Sbjct: 1301 EFLKNAPNDASYDAVRQSVVVLMGSLAKHLDKSDPKVKPIVAKLIAALSTPSQQVQESVA 1360
Query: 70 KCLGPLVSKVKEYQVETIVDTLCTNMLSDKEQLRDISSIGLKTVIGELPPASSGSALAAN 129
CL PLV +KE I + + SDK R ++ GL ++ G + +
Sbjct: 1361 SCLPPLVPAIKEDAGGMIQRLMQQLLESDKYAERKGAAYGLAGLV-------KGLGILSL 1413
Query: 130 VCKKITGRLTSAIAKQEDVSVQLEALDIMADMLSRQGGLLVNFHPSILTCLLPQLTSPRL 189
+++ LT AI +++ + AL + + G L + +L LL
Sbjct: 1414 KQQEMMAALTDAIQDKKNFRRREGALFAFEMLCTMLGKLFEPYVVHVLPHLLLCFGDGNQ 1473
Query: 190 AVRKRTIIALGHLVMSCGNIVFVDLIEHLLSELSKNDSMSTTRTYIQCIAAISRQAGHRI 249
VR+ VMS + V L+ L + +S T ++ + A++ A ++
Sbjct: 1474 YVRE-AADDCAKAVMSNLSAHGVKLVLPSLLAALEEESWRTKAGSVELLGAMAYCAPKQL 1532
Query: 250 GEYLEKIIPL---VVKFCNVDDDELREYCIQAFESFVRRCPKEVYPHVSTIINICLKYLT 306
L I+P V+ +V + + ++ S +R P + I + L LT
Sbjct: 1533 SSCLPNIVPKLTEVLTDSHVKVQKAGQQALRQIGSVIRN------PEILAIAPVLLDALT 1586
Query: 307 YDPN 310
DP+
Sbjct: 1587 -DPS 1589
>gi|11545835 TSPY-like 2 [Homo sapiens]
Length = 693
Score = 40.4 bits (93), Expect = 0.010
Identities = 18/31 (58%), Positives = 20/31 (64%)
Query: 314 DDEDEDENAMDADGGDDDDQGSDDEYSDDDD 344
DDED D N D +G DDD D+E SDDDD
Sbjct: 570 DDEDNDGNEGDNEGSDDDGNEGDNEGSDDDD 600
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 39.7 bits (91), Expect = 0.018
Identities = 26/89 (29%), Positives = 43/89 (48%), Gaps = 8/89 (8%)
Query: 267 DDDELREYCIQAFESFVRRCPKEVYPHVSTIINICLKYLTYDPNYNYDDEDEDENAMDAD 326
DDDE + +A E+ + K + ++ + K + D + DDEDED+ D D
Sbjct: 199 DDDEEDDSEEEAMETTPAKGKK-----AAKVVPVKAKNVAEDEDEEEDDEDEDD---DDD 250
Query: 327 GGDDDDQGSDDEYSDDDDMSWKVRRAAAK 355
D+DD DDE ++++ V+ A K
Sbjct: 251 EDDEDDDDEDDEEEEEEEEEEPVKEAPGK 279
Score = 31.2 bits (69), Expect = 6.4
Identities = 18/43 (41%), Positives = 23/43 (53%), Gaps = 12/43 (27%)
Query: 314 DDEDEDEN-------AMDADGG-----DDDDQGSDDEYSDDDD 344
DDEDEDE+ AM A D+DD+ +D+ DDDD
Sbjct: 159 DDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDD 201
>gi|214010175 CLIP-associating protein 1 isoform 3 [Homo sapiens]
Length = 1471
Score = 38.5 bits (88), Expect = 0.040
Identities = 44/218 (20%), Positives = 105/218 (48%), Gaps = 25/218 (11%)
Query: 8 ISNLLEKMTSSDK--DFRFMATNDLMTELQKDSIKLDDDSERKVVKMILKLLEDKNGEVQ 65
+++LL+++++ ++ + R A +L+ ++DS+ + ++ + ++ ++L+ L DK+ ++
Sbjct: 1237 VADLLKELSNHNERVEERKGALLELLKITREDSLGVWEEHFKTILLLLLETLGDKDHSIR 1296
Query: 66 NLAVKCLGPLV----SKVKEYQVETIVDTLCTNMLSDKEQLRDISSIGLKTVIGELPPAS 121
LA++ L ++ ++ K Y TI+ TL + S KE +R
Sbjct: 1297 ALALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVVR--------------AAEE 1342
Query: 122 SGSALAANVCKKITGRLTSAIAKQEDVSVQLEALDIMADMLSR-QGGLLVNFHPSILTCL 180
+ S LA+++ + ++ I + D + L A+ + ++ R L+ I+ L
Sbjct: 1343 AASTLASSIHPEQCIKVLCPIIQTADYPINLAAIKMQTKVVERIAKESLLQLLVDIIPGL 1402
Query: 181 LPQLTSPRLAVRKRTIIALGHLVMSCGNIVFVDLIEHL 218
L + +VRK ++ L ++ +++ DL HL
Sbjct: 1403 LQGYDNTESSVRKASVFCL----VAIYSVIGEDLKPHL 1436
Score = 32.3 bits (72), Expect = 2.9
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 3/91 (3%)
Query: 425 LTMLQSQVPNIVKALHKQMKEKSVKTRQCCFNMLTELVNV-LPGALTQHIPVLVPGIIFS 483
L + + +P ++ + KSV R+ CF L L+ +L +HI VL I
Sbjct: 435 LIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSLERHISVLAETIKKG 494
Query: 484 LNDKSSSSNLKIDALSCLYVILCNHSPQVFH 514
++D + S +I+A C + + S + H
Sbjct: 495 IHD--ADSEARIEARKCYWGFHSHFSREAEH 523
>gi|214010173 CLIP-associating protein 1 isoform 2 [Homo sapiens]
Length = 1479
Score = 38.5 bits (88), Expect = 0.040
Identities = 44/218 (20%), Positives = 105/218 (48%), Gaps = 25/218 (11%)
Query: 8 ISNLLEKMTSSDK--DFRFMATNDLMTELQKDSIKLDDDSERKVVKMILKLLEDKNGEVQ 65
+++LL+++++ ++ + R A +L+ ++DS+ + ++ + ++ ++L+ L DK+ ++
Sbjct: 1245 VADLLKELSNHNERVEERKGALLELLKITREDSLGVWEEHFKTILLLLLETLGDKDHSIR 1304
Query: 66 NLAVKCLGPLV----SKVKEYQVETIVDTLCTNMLSDKEQLRDISSIGLKTVIGELPPAS 121
LA++ L ++ ++ K Y TI+ TL + S KE +R
Sbjct: 1305 ALALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVVR--------------AAEE 1350
Query: 122 SGSALAANVCKKITGRLTSAIAKQEDVSVQLEALDIMADMLSR-QGGLLVNFHPSILTCL 180
+ S LA+++ + ++ I + D + L A+ + ++ R L+ I+ L
Sbjct: 1351 AASTLASSIHPEQCIKVLCPIIQTADYPINLAAIKMQTKVVERIAKESLLQLLVDIIPGL 1410
Query: 181 LPQLTSPRLAVRKRTIIALGHLVMSCGNIVFVDLIEHL 218
L + +VRK ++ L ++ +++ DL HL
Sbjct: 1411 LQGYDNTESSVRKASVFCL----VAIYSVIGEDLKPHL 1444
Score = 32.3 bits (72), Expect = 2.9
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 3/91 (3%)
Query: 425 LTMLQSQVPNIVKALHKQMKEKSVKTRQCCFNMLTELVNV-LPGALTQHIPVLVPGIIFS 483
L + + +P ++ + KSV R+ CF L L+ +L +HI VL I
Sbjct: 435 LIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSLERHISVLAETIKKG 494
Query: 484 LNDKSSSSNLKIDALSCLYVILCNHSPQVFH 514
++D + S +I+A C + + S + H
Sbjct: 495 IHD--ADSEARIEARKCYWGFHSHFSREAEH 523
>gi|31563537 CLIP-associating protein 1 isoform 1 [Homo sapiens]
Length = 1538
Score = 38.5 bits (88), Expect = 0.040
Identities = 44/218 (20%), Positives = 105/218 (48%), Gaps = 25/218 (11%)
Query: 8 ISNLLEKMTSSDK--DFRFMATNDLMTELQKDSIKLDDDSERKVVKMILKLLEDKNGEVQ 65
+++LL+++++ ++ + R A +L+ ++DS+ + ++ + ++ ++L+ L DK+ ++
Sbjct: 1304 VADLLKELSNHNERVEERKGALLELLKITREDSLGVWEEHFKTILLLLLETLGDKDHSIR 1363
Query: 66 NLAVKCLGPLV----SKVKEYQVETIVDTLCTNMLSDKEQLRDISSIGLKTVIGELPPAS 121
LA++ L ++ ++ K Y TI+ TL + S KE +R
Sbjct: 1364 ALALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVVR--------------AAEE 1409
Query: 122 SGSALAANVCKKITGRLTSAIAKQEDVSVQLEALDIMADMLSR-QGGLLVNFHPSILTCL 180
+ S LA+++ + ++ I + D + L A+ + ++ R L+ I+ L
Sbjct: 1410 AASTLASSIHPEQCIKVLCPIIQTADYPINLAAIKMQTKVVERIAKESLLQLLVDIIPGL 1469
Query: 181 LPQLTSPRLAVRKRTIIALGHLVMSCGNIVFVDLIEHL 218
L + +VRK ++ L ++ +++ DL HL
Sbjct: 1470 LQGYDNTESSVRKASVFCL----VAIYSVIGEDLKPHL 1503
Score = 32.3 bits (72), Expect = 2.9
Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 3/91 (3%)
Query: 425 LTMLQSQVPNIVKALHKQMKEKSVKTRQCCFNMLTELVNV-LPGALTQHIPVLVPGIIFS 483
L + + +P ++ + KSV R+ CF L L+ +L +HI VL I
Sbjct: 435 LIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSLERHISVLAETIKKG 494
Query: 484 LNDKSSSSNLKIDALSCLYVILCNHSPQVFH 514
++D + S +I+A C + + S + H
Sbjct: 495 IHD--ADSEARIEARKCYWGFHSHFSREAEH 523
>gi|23510381 transportin 1 isoform 2 [Homo sapiens]
Length = 890
Score = 38.1 bits (87), Expect = 0.052
Identities = 80/444 (18%), Positives = 172/444 (38%), Gaps = 63/444 (14%)
Query: 129 NVCKKITGRLTSAIAKQEDVSVQLEALDIMADMLSRQGGLLVNFHPSILTCLLPQLTSPR 188
N C+ G L Q+ E LD +D+L R +++ P++ S
Sbjct: 143 NTCEGAFGAL------QKICEDSAEILD--SDVLDRPLNIMIPKFLQFFKHSSPKIRSHA 194
Query: 189 LAVRKRTIIALGHLVMSCGNIVFVDLIEHLLSELSKNDSMSTTRTYIQCIAAISRQAGHR 248
+A + II+ +M + +D L L+ ++ + + + + R
Sbjct: 195 VACVNQFIISRTQALM-----LHIDSFIENLFALAGDEEPEVRKNVCRALVMLLEVRMDR 249
Query: 249 IGEYLEKIIPLVVKFCNVDDDELREYCIQAFESFVRR--CPKEVYPHVSTIINIC---LK 303
+ ++ I+ +++ D+ + + + + + C + H+ +I + +K
Sbjct: 250 LLPHMHNIVEYMLQRTQDQDENVALEACEFWLTLAEQPICKDVLVRHLPKLIPVLVNGMK 309
Query: 304 YLTYDPNYNYDDEDEDENAMDAD-------------------GGDDDDQGSDDEYSDDDD 344
Y D D +EDE D++ G +++ DDE DDD
Sbjct: 310 YSDIDIILLKGDVEEDETIPDSEQDIRPRFHRSRTVAQQHDEDGIEEEDDDDDEIDDDDT 369
Query: 345 MS-WKVRRAAAKCLDAVVST-RHEMLPEFYKTVSPALISRFKEREEN-------VKADVF 395
+S W +R+ +A LD + + R E+LP + L +E+ +
Sbjct: 370 ISDWNLRKCSAAALDVLANVYRDELLPHILPLLKELLFHHEWVVKESGILVLGAIAEGCM 429
Query: 396 HAYLSLLKQTRP-VQSWLCDPDAMEQGETPLTM------LQSQVPN-----IVKALHKQM 443
+ L + P + L D A+ + T T+ + SQ P+ ++ L K++
Sbjct: 430 QGMIPYLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWVVSQPPDTYLKPLMTELLKRI 489
Query: 444 KEKSVKTRQCCFNMLTELVNVLPGALTQHIPVLVPGIIFSLNDKSSSSNLKI--DALSCL 501
+ + + ++ + L L ++ ++ ++F+ + K NL I DA+ L
Sbjct: 490 LDSNKRVQEAACSAFATLEEEACTELVPYLAYILDTLVFAFS-KYQHKNLLILYDAIGTL 548
Query: 502 YVILCNHSPQVFHPHVQALVPPVV 525
+ +H + ++Q L+PP++
Sbjct: 549 ADSVGHHLNK--PEYIQMLMPPLI 570
>gi|133925811 transportin 1 isoform 1 [Homo sapiens]
Length = 898
Score = 38.1 bits (87), Expect = 0.052
Identities = 80/444 (18%), Positives = 172/444 (38%), Gaps = 63/444 (14%)
Query: 129 NVCKKITGRLTSAIAKQEDVSVQLEALDIMADMLSRQGGLLVNFHPSILTCLLPQLTSPR 188
N C+ G L Q+ E LD +D+L R +++ P++ S
Sbjct: 151 NTCEGAFGAL------QKICEDSAEILD--SDVLDRPLNIMIPKFLQFFKHSSPKIRSHA 202
Query: 189 LAVRKRTIIALGHLVMSCGNIVFVDLIEHLLSELSKNDSMSTTRTYIQCIAAISRQAGHR 248
+A + II+ +M + +D L L+ ++ + + + + R
Sbjct: 203 VACVNQFIISRTQALM-----LHIDSFIENLFALAGDEEPEVRKNVCRALVMLLEVRMDR 257
Query: 249 IGEYLEKIIPLVVKFCNVDDDELREYCIQAFESFVRR--CPKEVYPHVSTIINIC---LK 303
+ ++ I+ +++ D+ + + + + + C + H+ +I + +K
Sbjct: 258 LLPHMHNIVEYMLQRTQDQDENVALEACEFWLTLAEQPICKDVLVRHLPKLIPVLVNGMK 317
Query: 304 YLTYDPNYNYDDEDEDENAMDAD-------------------GGDDDDQGSDDEYSDDDD 344
Y D D +EDE D++ G +++ DDE DDD
Sbjct: 318 YSDIDIILLKGDVEEDETIPDSEQDIRPRFHRSRTVAQQHDEDGIEEEDDDDDEIDDDDT 377
Query: 345 MS-WKVRRAAAKCLDAVVST-RHEMLPEFYKTVSPALISRFKEREEN-------VKADVF 395
+S W +R+ +A LD + + R E+LP + L +E+ +
Sbjct: 378 ISDWNLRKCSAAALDVLANVYRDELLPHILPLLKELLFHHEWVVKESGILVLGAIAEGCM 437
Query: 396 HAYLSLLKQTRP-VQSWLCDPDAMEQGETPLTM------LQSQVPN-----IVKALHKQM 443
+ L + P + L D A+ + T T+ + SQ P+ ++ L K++
Sbjct: 438 QGMIPYLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWVVSQPPDTYLKPLMTELLKRI 497
Query: 444 KEKSVKTRQCCFNMLTELVNVLPGALTQHIPVLVPGIIFSLNDKSSSSNLKI--DALSCL 501
+ + + ++ + L L ++ ++ ++F+ + K NL I DA+ L
Sbjct: 498 LDSNKRVQEAACSAFATLEEEACTELVPYLAYILDTLVFAFS-KYQHKNLLILYDAIGTL 556
Query: 502 YVILCNHSPQVFHPHVQALVPPVV 525
+ +H + ++Q L+PP++
Sbjct: 557 ADSVGHHLNK--PEYIQMLMPPLI 578
>gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens]
Length = 619
Score = 38.1 bits (87), Expect = 0.052
Identities = 14/51 (27%), Positives = 31/51 (60%)
Query: 294 VSTIINICLKYLTYDPNYNYDDEDEDENAMDADGGDDDDQGSDDEYSDDDD 344
+ I+N+CL+ + + +D+ ED++ + D ++D++ ++E DDDD
Sbjct: 116 IQCIVNVCLEIMEPGGDGGEEDDKEDDDDDEDDDDEEDEEEEEEEEEDDDD 166
>gi|50083293 coiled-coil domain containing 123 [Homo sapiens]
Length = 783
Score = 38.1 bits (87), Expect = 0.052
Identities = 31/112 (27%), Positives = 46/112 (41%), Gaps = 14/112 (12%)
Query: 1120 KMLTFLMLVRLSTLCPSAVLQRLDRLVEPLRATCTT--------------KVKANSVKQE 1165
K+ LML+ T L +E LRA C K N +K +
Sbjct: 464 KLTKQLMLLEAKTHGQEKELAENREQLEILRAKCQELKTHSDGKIAVEVHKSIVNELKSQ 523
Query: 1166 FEKQDELKRSAMRAVAALLTIPEAEKSPLMSEFQSQISSNPELAAIFESIQK 1217
+K++E +R+ M + LT+ +A+K L+ E S N L A E QK
Sbjct: 524 LQKEEEKERAEMEELMEKLTVLQAQKKSLLLEKNSLTEQNKALEAELERAQK 575
>gi|22212943 ubiquitin-conjugating enzyme UBC3B [Homo sapiens]
Length = 238
Score = 37.7 bits (86), Expect = 0.068
Identities = 17/33 (51%), Positives = 22/33 (66%)
Query: 305 LTYDPNYNYDDEDEDENAMDADGGDDDDQGSDD 337
L YD Y+ D +DEDE DAD DDDD G+++
Sbjct: 205 LLYDDLYDDDIDDEDEEEEDADCYDDDDSGNEE 237
>gi|39780552 Vac14 homolog [Homo sapiens]
Length = 782
Score = 37.0 bits (84), Expect = 0.12
Identities = 30/108 (27%), Positives = 51/108 (47%), Gaps = 5/108 (4%)
Query: 215 IEHLLSELSKNDSMS----TTRTYIQCIAAISRQAGHRIGEYLEKIIPLVVKFCNVDDDE 270
I+H++ LS+ ++S + + + +AA S G G YL+++I V+ N D
Sbjct: 49 IKHVIQTLSQEFALSQHPHSRKGGLIGLAACSIALGKDSGLYLKELIEPVLTCFNDADSR 108
Query: 271 LREYCIQAFESFVRRCPKEVYPHVSTIINICLKYLTYDPNYNYDDEDE 318
LR Y +A + V+ V PH + + + L L DP+ N E
Sbjct: 109 LRYYACEALYNIVKVARGAVLPHFNVLFD-GLSKLAADPDPNVKSGSE 155
>gi|30089916 phosphofurin acidic cluster sorting protein 1 [Homo
sapiens]
Length = 963
Score = 36.6 bits (83), Expect = 0.15
Identities = 23/77 (29%), Positives = 37/77 (48%), Gaps = 6/77 (7%)
Query: 312 NYDDEDEDENAMDADGGDDDDQGSDDEYSDDDDMSWKVRRAAAKCLDAVVSTRHEMLPEF 371
NY +E+E+ + + +G DD G D Y D+D KV++ K TR + +
Sbjct: 276 NYSEEEEESFSSEQEGSDDPLHGQDLFYEDED--LRKVKKTRRKLTSTSAITRQPNIKQK 333
Query: 372 YKTVSPALISRFKEREE 388
+ AL+ RFK +E
Sbjct: 334 F----VALLKRFKVSDE 346
>gi|42740903 MTERF domain containing 2 [Homo sapiens]
Length = 381
Score = 36.2 bits (82), Expect = 0.20
Identities = 13/31 (41%), Positives = 21/31 (67%)
Query: 314 DDEDEDENAMDADGGDDDDQGSDDEYSDDDD 344
D++D+DE D D D+DD DD+ ++D+D
Sbjct: 342 DEDDDDEEDNDEDDNDEDDDDEDDDEAEDND 372
Score = 36.2 bits (82), Expect = 0.20
Identities = 15/31 (48%), Positives = 20/31 (64%)
Query: 314 DDEDEDENAMDADGGDDDDQGSDDEYSDDDD 344
+D DED+N D D DDD+ +DE DDD+
Sbjct: 349 EDNDEDDNDEDDDDEDDDEAEDNDEDEDDDE 379
Score = 35.4 bits (80), Expect = 0.34
Identities = 14/31 (45%), Positives = 20/31 (64%)
Query: 314 DDEDEDENAMDADGGDDDDQGSDDEYSDDDD 344
D+ED DE+ D D D+DD ++D D+DD
Sbjct: 347 DEEDNDEDDNDEDDDDEDDDEAEDNDEDEDD 377
Score = 33.1 bits (74), Expect = 1.7
Identities = 13/28 (46%), Positives = 18/28 (64%)
Query: 317 DEDENAMDADGGDDDDQGSDDEYSDDDD 344
DEDE+ D + D+DD DD+ DDD+
Sbjct: 340 DEDEDDDDEEDNDEDDNDEDDDDEDDDE 367
Score = 30.8 bits (68), Expect = 8.3
Identities = 13/37 (35%), Positives = 22/37 (59%), Gaps = 4/37 (10%)
Query: 308 DPNYNYDDEDEDENAMDADGGDDDDQGSDDEYSDDDD 344
D + D++D DE+ D +DDD+ D++ +DDD
Sbjct: 346 DDEEDNDEDDNDED----DDDEDDDEAEDNDEDEDDD 378
>gi|157266317 ataxia telangiectasia and Rad3 related protein [Homo
sapiens]
Length = 2644
Score = 36.2 bits (82), Expect = 0.20
Identities = 28/111 (25%), Positives = 50/111 (45%), Gaps = 4/111 (3%)
Query: 856 ELKSVILEAFSSPSEEVKSAASYALGSISVGNLPEYLPFVLQEITSQPKRQYLLLHSLKE 915
++K+V+ E SE + L ++ + E + + +TS + Y L +
Sbjct: 1263 KIKAVLQEYRKETSESTDLQTTLQLSMKAIQH--ENVDVRIHALTSLKETLYKNQEKLIK 1320
Query: 916 IISSASVVGLKPYVENIWALLLKHCECAEEGTRNVVAECLGKLTLIDPETL 966
+ + V +P + + +LLK C+ A R + ECLG+L IDP L
Sbjct: 1321 YATDSETV--EPIISQLVTVLLKGCQDANSQARLLCGECLGELGAIDPGRL 1369
>gi|169218238 PREDICTED: similar to ataxia telangiectasia and Rad3
related protein, partial [Homo sapiens]
Length = 2105
Score = 36.2 bits (82), Expect = 0.20
Identities = 28/111 (25%), Positives = 50/111 (45%), Gaps = 4/111 (3%)
Query: 856 ELKSVILEAFSSPSEEVKSAASYALGSISVGNLPEYLPFVLQEITSQPKRQYLLLHSLKE 915
++K+V+ E SE + L ++ + E + + +TS + Y L +
Sbjct: 1021 KIKAVLQEYRKETSESTDLQTTLQLSMKAIQH--ENVDVRIHALTSLKETLYKNQEKLIK 1078
Query: 916 IISSASVVGLKPYVENIWALLLKHCECAEEGTRNVVAECLGKLTLIDPETL 966
+ + V +P + + +LLK C+ A R + ECLG+L IDP L
Sbjct: 1079 YATDSETV--EPIISQLVTVLLKGCQDANSQARLLCGECLGELGAIDPGRL 1127
>gi|115529449 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 36.2 bits (82), Expect = 0.20
Identities = 16/39 (41%), Positives = 20/39 (51%)
Query: 308 DPNYNYDDEDEDENAMDADGGDDDDQGSDDEYSDDDDMS 346
D + DDEDEDE D + GD + G D S +D S
Sbjct: 643 DDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDES 681
>gi|115529451 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 36.2 bits (82), Expect = 0.20
Identities = 16/39 (41%), Positives = 20/39 (51%)
Query: 308 DPNYNYDDEDEDENAMDADGGDDDDQGSDDEYSDDDDMS 346
D + DDEDEDE D + GD + G D S +D S
Sbjct: 643 DDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDES 681
>gi|7657671 upstream binding transcription factor, RNA polymerase I
isoform a [Homo sapiens]
Length = 764
Score = 36.2 bits (82), Expect = 0.20
Identities = 16/39 (41%), Positives = 20/39 (51%)
Query: 308 DPNYNYDDEDEDENAMDADGGDDDDQGSDDEYSDDDDMS 346
D + DDEDEDE D + GD + G D S +D S
Sbjct: 680 DDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDES 718
>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
Length = 1390
Score = 35.8 bits (81), Expect = 0.26
Identities = 14/32 (43%), Positives = 21/32 (65%)
Query: 313 YDDEDEDENAMDADGGDDDDQGSDDEYSDDDD 344
++D+ EDE+ D D DDDD DDE +D++
Sbjct: 253 HEDDGEDEDDEDDDDDDDDDDDDDDEDDEDEE 284
Score = 35.0 bits (79), Expect = 0.44
Identities = 23/80 (28%), Positives = 34/80 (42%), Gaps = 9/80 (11%)
Query: 308 DPNYNYDDEDEDENAMDADGGDDDDQGSDDEYSDDDDMSWKVRRAAAKCLDAVV------ 361
D + D EDED+ D D DDDD +D+ ++D +R + A V
Sbjct: 250 DQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDEDEEDGEEENQKRYYLRQRKATVYYQAPL 309
Query: 362 -STRHEMLPEFYKT--VSPA 378
RH+ P + + SPA
Sbjct: 310 EKPRHQRKPNIFYSGPASPA 329
Score = 34.3 bits (77), Expect = 0.75
Identities = 12/31 (38%), Positives = 20/31 (64%)
Query: 314 DDEDEDENAMDADGGDDDDQGSDDEYSDDDD 344
+D++ +++ D D DDDD DD+ DD+D
Sbjct: 249 EDQEHEDDGEDEDDEDDDDDDDDDDDDDDED 279
Score = 33.5 bits (75), Expect = 1.3
Identities = 15/30 (50%), Positives = 20/30 (66%), Gaps = 1/30 (3%)
Query: 315 DEDEDENAMDADGGDDDDQGSDDEYSDDDD 344
+E ED+ D DG D+DD+ DD+ DDDD
Sbjct: 246 EEGEDQEHED-DGEDEDDEDDDDDDDDDDD 274
Score = 31.2 bits (69), Expect = 6.4
Identities = 12/31 (38%), Positives = 18/31 (58%)
Query: 314 DDEDEDENAMDADGGDDDDQGSDDEYSDDDD 344
+ +E E+ D G+D+D DD+ DDDD
Sbjct: 243 ESSEEGEDQEHEDDGEDEDDEDDDDDDDDDD 273
>gi|209969838 transportin 2 (importin 3, karyopherin beta 2b)
isoform 1 [Homo sapiens]
Length = 897
Score = 35.8 bits (81), Expect = 0.26
Identities = 41/207 (19%), Positives = 82/207 (39%), Gaps = 29/207 (14%)
Query: 191 VRKRTIIALGHLVMSCGNIVFVDL---IEHLLSELSKNDSMSTTRTYIQCIAAISRQAGH 247
+R I + +M + ++ IEHL + L+ +D + + + +
Sbjct: 188 IRSHAIACVNQFIMDRAQALMDNIDTFIEHLFA-LAVDDDPEVRKNVCRALVMLLEVRID 246
Query: 248 RIGEYLEKIIPLVVKFCNVDDDELREYCIQAFESFVRR--CPKEVYPHVSTIINIC---L 302
R+ ++ II +++ D+ + + + + + C + + H+ +I I +
Sbjct: 247 RLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICKEVLASHLVQLIPILVNGM 306
Query: 303 KYLTYDPNYNYDDEDEDENAMDADGG----------------DDDDQGSDDEYSDDDD-- 344
KY D D +EDE D++ + GS+D DDDD
Sbjct: 307 KYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAEDDDDDDA 366
Query: 345 -MSWKVRRAAAKCLDAVVST-RHEMLP 369
W +R+ +A LD + + R E+LP
Sbjct: 367 LSDWNLRKCSAAALDVLANVFREELLP 393
Score = 30.8 bits (68), Expect = 8.3
Identities = 38/191 (19%), Positives = 71/191 (37%), Gaps = 28/191 (14%)
Query: 966 LLPRLKGYLISGSSYARSSVVTAVKFTISDHPQPIDPLLKN-----CIGDFLKTLEDPDL 1020
LLP+L L S A++ D + +D N I FL+ +
Sbjct: 127 LLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQFFKHCSP 186
Query: 1021 NVRRVALVTFNSAAHNKPSLIRDLLDTVLPHLYNETKVRKELIREVEMGPFKHTVDDGLD 1080
+R A+ N ++ + D +DT + HL F VDD +
Sbjct: 187 KIRSHAIACVNQFIMDRAQALMDNIDTFIEHL------------------FALAVDDDPE 228
Query: 1081 IRKAAFECMYTLLDSCLDRL--DIFEFLNHVEDGLKDHYD---IKMLTFLMLVRLSTLCP 1135
+RK + LL+ +DRL + + ++ +DH + ++ F + + +C
Sbjct: 229 VRKNVCRALVMLLEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICK 288
Query: 1136 SAVLQRLDRLV 1146
+ L +L+
Sbjct: 289 EVLASHLVQLI 299
>gi|209969836 transportin 2 (importin 3, karyopherin beta 2b)
isoform 3 [Homo sapiens]
Length = 887
Score = 35.8 bits (81), Expect = 0.26
Identities = 41/207 (19%), Positives = 82/207 (39%), Gaps = 29/207 (14%)
Query: 191 VRKRTIIALGHLVMSCGNIVFVDL---IEHLLSELSKNDSMSTTRTYIQCIAAISRQAGH 247
+R I + +M + ++ IEHL + L+ +D + + + +
Sbjct: 188 IRSHAIACVNQFIMDRAQALMDNIDTFIEHLFA-LAVDDDPEVRKNVCRALVMLLEVRID 246
Query: 248 RIGEYLEKIIPLVVKFCNVDDDELREYCIQAFESFVRR--CPKEVYPHVSTIINIC---L 302
R+ ++ II +++ D+ + + + + + C + + H+ +I I +
Sbjct: 247 RLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICKEVLASHLVQLIPILVNGM 306
Query: 303 KYLTYDPNYNYDDEDEDENAMDADGG----------------DDDDQGSDDEYSDDDD-- 344
KY D D +EDE D++ + GS+D DDDD
Sbjct: 307 KYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAEDDDDDDA 366
Query: 345 -MSWKVRRAAAKCLDAVVST-RHEMLP 369
W +R+ +A LD + + R E+LP
Sbjct: 367 LSDWNLRKCSAAALDVLANVFREELLP 393
Score = 30.8 bits (68), Expect = 8.3
Identities = 38/191 (19%), Positives = 71/191 (37%), Gaps = 28/191 (14%)
Query: 966 LLPRLKGYLISGSSYARSSVVTAVKFTISDHPQPIDPLLKN-----CIGDFLKTLEDPDL 1020
LLP+L L S A++ D + +D N I FL+ +
Sbjct: 127 LLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQFFKHCSP 186
Query: 1021 NVRRVALVTFNSAAHNKPSLIRDLLDTVLPHLYNETKVRKELIREVEMGPFKHTVDDGLD 1080
+R A+ N ++ + D +DT + HL F VDD +
Sbjct: 187 KIRSHAIACVNQFIMDRAQALMDNIDTFIEHL------------------FALAVDDDPE 228
Query: 1081 IRKAAFECMYTLLDSCLDRL--DIFEFLNHVEDGLKDHYD---IKMLTFLMLVRLSTLCP 1135
+RK + LL+ +DRL + + ++ +DH + ++ F + + +C
Sbjct: 229 VRKNVCRALVMLLEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICK 288
Query: 1136 SAVLQRLDRLV 1146
+ L +L+
Sbjct: 289 EVLASHLVQLI 299
>gi|48675813 transportin 2 (importin 3, karyopherin beta 2b) isoform
2 [Homo sapiens]
Length = 887
Score = 35.8 bits (81), Expect = 0.26
Identities = 41/207 (19%), Positives = 82/207 (39%), Gaps = 29/207 (14%)
Query: 191 VRKRTIIALGHLVMSCGNIVFVDL---IEHLLSELSKNDSMSTTRTYIQCIAAISRQAGH 247
+R I + +M + ++ IEHL + L+ +D + + + +
Sbjct: 188 IRSHAIACVNQFIMDRAQALMDNIDTFIEHLFA-LAVDDDPEVRKNVCRALVMLLEVRID 246
Query: 248 RIGEYLEKIIPLVVKFCNVDDDELREYCIQAFESFVRR--CPKEVYPHVSTIINIC---L 302
R+ ++ II +++ D+ + + + + + C + + H+ +I I +
Sbjct: 247 RLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICKEVLASHLVQLIPILVNGM 306
Query: 303 KYLTYDPNYNYDDEDEDENAMDADGG----------------DDDDQGSDDEYSDDDD-- 344
KY D D +EDE D++ + GS+D DDDD
Sbjct: 307 KYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAERPDGSEDAEDDDDDDA 366
Query: 345 -MSWKVRRAAAKCLDAVVST-RHEMLP 369
W +R+ +A LD + + R E+LP
Sbjct: 367 LSDWNLRKCSAAALDVLANVFREELLP 393
Score = 30.8 bits (68), Expect = 8.3
Identities = 38/191 (19%), Positives = 71/191 (37%), Gaps = 28/191 (14%)
Query: 966 LLPRLKGYLISGSSYARSSVVTAVKFTISDHPQPIDPLLKN-----CIGDFLKTLEDPDL 1020
LLP+L L S A++ D + +D N I FL+ +
Sbjct: 127 LLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKFLQFFKHCSP 186
Query: 1021 NVRRVALVTFNSAAHNKPSLIRDLLDTVLPHLYNETKVRKELIREVEMGPFKHTVDDGLD 1080
+R A+ N ++ + D +DT + HL F VDD +
Sbjct: 187 KIRSHAIACVNQFIMDRAQALMDNIDTFIEHL------------------FALAVDDDPE 228
Query: 1081 IRKAAFECMYTLLDSCLDRL--DIFEFLNHVEDGLKDHYD---IKMLTFLMLVRLSTLCP 1135
+RK + LL+ +DRL + + ++ +DH + ++ F + + +C
Sbjct: 229 VRKNVCRALVMLLEVRIDRLIPHMHSIIQYMLQRTQDHDENVALEACEFWLTLAEQPICK 288
Query: 1136 SAVLQRLDRLV 1146
+ L +L+
Sbjct: 289 EVLASHLVQLI 299
>gi|7661566 integrator complex subunit 7 [Homo sapiens]
Length = 962
Score = 35.8 bits (81), Expect = 0.26
Identities = 32/136 (23%), Positives = 66/136 (48%), Gaps = 6/136 (4%)
Query: 27 TNDLMTELQKDSIKLDDDSERKVVKMILKLLEDKNGEVQ---NLAVKCLGPLVSKVKEYQ 83
TN ++ +KD + L+ D+ + +++ +D + Q +A+ C+ L +K + +
Sbjct: 368 TNITVSCQEKDLLALEQDAVFGLESLLVLCSQDDSPGAQATLKIALNCMVKL-AKGRPHL 426
Query: 84 VETIVDTLCTNMLSDKEQLRDISSIGLKTVIGELPPASSGSALAANVCKKITGRLTSAIA 143
+++V+TL T + S ++ R + L + +LP G K+ GR SA
Sbjct: 427 SQSVVETLLTQLHSAQDAARILMCHCLAAIAMQLPVLGDGMLGDLMELYKVIGR--SATD 484
Query: 144 KQEDVSVQLEALDIMA 159
KQ+++ V L + +A
Sbjct: 485 KQQELLVSLATVIFVA 500
>gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding
protein homolog 1 [Homo sapiens]
Length = 557
Score = 35.8 bits (81), Expect = 0.26
Identities = 15/38 (39%), Positives = 23/38 (60%), Gaps = 1/38 (2%)
Query: 308 DPNYNYDDEDEDENAMDADGGDDDDQGSDDEYSDDDDM 345
D YNY+ DEDE + D G ++++ DD+ DDD +
Sbjct: 4 DEGYNYEF-DEDEECSEEDSGAEEEEDEDDDEPDDDTL 40
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,635,831
Number of Sequences: 37866
Number of extensions: 1823549
Number of successful extensions: 8253
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 51
Number of HSP's successfully gapped in prelim test: 56
Number of HSP's that attempted gapping in prelim test: 6978
Number of HSP's gapped (non-prelim): 960
length of query: 1230
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1116
effective length of database: 13,930,794
effective search space: 15546766104
effective search space used: 15546766104
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.