Guide to the Human Genome
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Search of human proteins with 113430845

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|113430845 PREDICTED: similar to protein kinase,
DNA-activated, catalytic polypeptide [Homo sapiens]
         (4096 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|113430845 PREDICTED: similar to protein kinase, DNA-activated...  8161   0.0  
gi|126032350 protein kinase, DNA-activated, catalytic polypeptid...  8147   0.0  
gi|13654237 protein kinase, DNA-activated, catalytic polypeptide...  8131   0.0  
gi|157266317 ataxia telangiectasia and Rad3 related protein [Hom...   142   9e-33
gi|169165926 PREDICTED: similar to ataxia telangiectasia and Rad...   142   9e-33
gi|4826730 FK506 binding protein 12-rapamycin associated protein...   140   3e-32
gi|20336199 ataxia telangiectasia mutated isoform 2 [Homo sapiens]    112   1e-23
gi|71902540 ataxia telangiectasia mutated isoform 1 [Homo sapiens]    112   1e-23
gi|169218268 PREDICTED: similar to Serine-protein kinase ATM, pa...   112   1e-23
gi|62243658 PI-3-kinase-related kinase SMG-1 [Homo sapiens]            95   1e-18
gi|34761064 catalytic phosphatidylinositol 3-kinase 3 [Homo sapi...    68   2e-10
gi|4507691 transformation/transcription domain-associated protei...    68   2e-10
gi|21237725 phosphoinositide-3-kinase, catalytic, gamma polypept...    67   5e-10
gi|156564405 catalytic phosphatidylinositol 3-kinase delta [Homo...    61   2e-08
gi|5453894 catalytic phosphatidylinositol 3-kinase beta [Homo sa...    56   6e-07
gi|169218238 PREDICTED: similar to ataxia telangiectasia and Rad...    52   2e-05
gi|4505809 catalytic phosphatidylinositol 4-kinase beta [Homo sa...    48   2e-04
gi|54792082 phosphoinositide-3-kinase, catalytic, alpha polypept...    46   9e-04
gi|194353959 phosphoinositide-3-kinase, class 2 gamma polypeptid...    46   9e-04
gi|194097347 phosphoinositide-3-kinase, class 2 beta polypeptide...    45   0.002
gi|157671929 phosphoinositide-3-kinase, class 2 alpha polypeptid...    44   0.003
gi|148886661 exportin 4 [Homo sapiens]                                 36   0.69 
gi|223941912 coiled-coil domain containing 135 [Homo sapiens]          36   0.90 
gi|188497683 FAST kinase domains 1 [Homo sapiens]                      35   1.5  
gi|4505807 phosphatidylinositol 4-kinase type 3 alpha isoform 1 ...    34   2.6  
gi|155030226 phosphatidylinositol 4-kinase type 3 alpha isoform ...    34   2.6  
gi|41352697 centromere protein I [Homo sapiens]                        34   2.6  
gi|239757646 PREDICTED: similar to phosphatidylinositol 4-kinase...    34   3.4  
gi|122937502 transmembrane channel-like 3 [Homo sapiens]               34   3.4  
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    33   5.8  

>gi|113430845 PREDICTED: similar to protein kinase, DNA-activated,
            catalytic polypeptide [Homo sapiens]
          Length = 4096

 Score = 8161 bits (21175), Expect = 0.0
 Identities = 4096/4096 (100%), Positives = 4096/4096 (100%)

Query: 1    MAGSGAGVRCSLLRLQETLSAADRCGAALAGHQLIRGLGQECVLSSSPAVLALQTSLVFS 60
            MAGSGAGVRCSLLRLQETLSAADRCGAALAGHQLIRGLGQECVLSSSPAVLALQTSLVFS
Sbjct: 1    MAGSGAGVRCSLLRLQETLSAADRCGAALAGHQLIRGLGQECVLSSSPAVLALQTSLVFS 60

Query: 61   RDFGLLVFVRKSLNSIEFRECREEILKFLCIFLEKMGQKIAPYSVEIKNTCTSVYTKDRA 120
            RDFGLLVFVRKSLNSIEFRECREEILKFLCIFLEKMGQKIAPYSVEIKNTCTSVYTKDRA
Sbjct: 61   RDFGLLVFVRKSLNSIEFRECREEILKFLCIFLEKMGQKIAPYSVEIKNTCTSVYTKDRA 120

Query: 121  AKCKIPALDLLIKLLQTFRSSRLMDEFKIGELFSKFYGELALKKKIPDTVLEKVYELLGL 180
            AKCKIPALDLLIKLLQTFRSSRLMDEFKIGELFSKFYGELALKKKIPDTVLEKVYELLGL
Sbjct: 121  AKCKIPALDLLIKLLQTFRSSRLMDEFKIGELFSKFYGELALKKKIPDTVLEKVYELLGL 180

Query: 181  LGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE 240
            LGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE
Sbjct: 181  LGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE 240

Query: 241  DPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKW 300
            DPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKW
Sbjct: 241  DPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKW 300

Query: 301  CAHTNVELKKAALSALESFLKQVSNMVAKNAEMHKNKLQYFMEQFYGIIRNVDSNNKELS 360
            CAHTNVELKKAALSALESFLKQVSNMVAKNAEMHKNKLQYFMEQFYGIIRNVDSNNKELS
Sbjct: 301  CAHTNVELKKAALSALESFLKQVSNMVAKNAEMHKNKLQYFMEQFYGIIRNVDSNNKELS 360

Query: 361  IAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTQTDTGDYRVYQMPSFLQSVASV 420
            IAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTQTDTGDYRVYQMPSFLQSVASV
Sbjct: 361  IAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTQTDTGDYRVYQMPSFLQSVASV 420

Query: 421  LLYLDTVPEVYTPVLEHLVVMQIDSFPQYSPKMQLVCCRAIVKVFLALAAKGPVLRNCIS 480
            LLYLDTVPEVYTPVLEHLVVMQIDSFPQYSPKMQLVCCRAIVKVFLALAAKGPVLRNCIS
Sbjct: 421  LLYLDTVPEVYTPVLEHLVVMQIDSFPQYSPKMQLVCCRAIVKVFLALAAKGPVLRNCIS 480

Query: 481  TVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQM 540
            TVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQM
Sbjct: 481  TVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQM 540

Query: 541  MDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGV 600
            MDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGV
Sbjct: 541  MDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGV 600

Query: 601  WMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRL 660
            WMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRL
Sbjct: 601  WMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRL 660

Query: 661  PLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAVKMKQ 720
            PLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAVKMKQ
Sbjct: 661  PLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAVKMKQ 720

Query: 721  YKDELLASCLTFLLSLPHNIIELDVRAYVPALQMAFKLGLSYTPLAEVGLNALEEWSIYI 780
            YKDELLASCLTFLLSLPHNIIELDVRAYVPALQMAFKLGLSYTPLAEVGLNALEEWSIYI
Sbjct: 721  YKDELLASCLTFLLSLPHNIIELDVRAYVPALQMAFKLGLSYTPLAEVGLNALEEWSIYI 780

Query: 781  DRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSRAAQKGFNKVVLKHLKKTKNL 840
            DRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSRAAQKGFNKVVLKHLKKTKNL
Sbjct: 781  DRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSRAAQKGFNKVVLKHLKKTKNL 840

Query: 841  SSNEAISLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDREKRLSFAVPFRE 900
            SSNEAISLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDREKRLSFAVPFRE
Sbjct: 841  SSNEAISLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDREKRLSFAVPFRE 900

Query: 901  MKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGKATQMPEGGQGAPPMYQ 960
            MKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGKATQMPEGGQGAPPMYQ
Sbjct: 901  MKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGKATQMPEGGQGAPPMYQ 960

Query: 961  LYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVSLLEAILDGIVDP 1020
            LYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVSLLEAILDGIVDP
Sbjct: 961  LYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVSLLEAILDGIVDP 1020

Query: 1021 VDSTLRDFCGRCIREFLKWSIKQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASL 1080
            VDSTLRDFCGRCIREFLKWSIKQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASL
Sbjct: 1021 VDSTLRDFCGRCIREFLKWSIKQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASL 1080

Query: 1081 AFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEK 1140
            AFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEK
Sbjct: 1081 AFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEK 1140

Query: 1141 KHVSLNKAKKRRLPRGFPPSASLCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPG 1200
            KHVSLNKAKKRRLPRGFPPSASLCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPG
Sbjct: 1141 KHVSLNKAKKRRLPRGFPPSASLCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPG 1200

Query: 1201 NRSPNLWLKDVLKEEGVSFLINTFEGGGCGQPSGILAQPTLLYLRGPFSLQATLCWLDLL 1260
            NRSPNLWLKDVLKEEGVSFLINTFEGGGCGQPSGILAQPTLLYLRGPFSLQATLCWLDLL
Sbjct: 1201 NRSPNLWLKDVLKEEGVSFLINTFEGGGCGQPSGILAQPTLLYLRGPFSLQATLCWLDLL 1260

Query: 1261 LAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFLESIAMHDIIAAEKCFGTGAAGN 1320
            LAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFLESIAMHDIIAAEKCFGTGAAGN
Sbjct: 1261 LAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFLESIAMHDIIAAEKCFGTGAAGN 1320

Query: 1321 RTSPQEGERYNYSKCTVVVRIMEFTTTLLNTSPEGWKLLKKDLCNTHLMRVLVQTLCEPA 1380
            RTSPQEGERYNYSKCTVVVRIMEFTTTLLNTSPEGWKLLKKDLCNTHLMRVLVQTLCEPA
Sbjct: 1321 RTSPQEGERYNYSKCTVVVRIMEFTTTLLNTSPEGWKLLKKDLCNTHLMRVLVQTLCEPA 1380

Query: 1381 SIGFNIGDVQVMAHLPDVCVNLMKALKMSPYKDILETHLREKITAQSIEELCAVNLYGPD 1440
            SIGFNIGDVQVMAHLPDVCVNLMKALKMSPYKDILETHLREKITAQSIEELCAVNLYGPD
Sbjct: 1381 SIGFNIGDVQVMAHLPDVCVNLMKALKMSPYKDILETHLREKITAQSIEELCAVNLYGPD 1440

Query: 1441 AQVDRSRLAAVVSACKQLHRAGLLHNILPSQSTDLHHSVGTELLSLVYKGIAPGDERQCL 1500
            AQVDRSRLAAVVSACKQLHRAGLLHNILPSQSTDLHHSVGTELLSLVYKGIAPGDERQCL
Sbjct: 1441 AQVDRSRLAAVVSACKQLHRAGLLHNILPSQSTDLHHSVGTELLSLVYKGIAPGDERQCL 1500

Query: 1501 PSLDLSCKQLASGLLELAFAFGGLCERLVSLLLNPAVLSTASLGSSQGSVIHFSHGEYFY 1560
            PSLDLSCKQLASGLLELAFAFGGLCERLVSLLLNPAVLSTASLGSSQGSVIHFSHGEYFY
Sbjct: 1501 PSLDLSCKQLASGLLELAFAFGGLCERLVSLLLNPAVLSTASLGSSQGSVIHFSHGEYFY 1560

Query: 1561 SLFSETINTELLKNLDLAVLELMQSSVDNTKMVSAVLNGMLDQSFRERANQKHQGLKLAT 1620
            SLFSETINTELLKNLDLAVLELMQSSVDNTKMVSAVLNGMLDQSFRERANQKHQGLKLAT
Sbjct: 1561 SLFSETINTELLKNLDLAVLELMQSSVDNTKMVSAVLNGMLDQSFRERANQKHQGLKLAT 1620

Query: 1621 TILQHWKKCDSWWAKDSPLETKMAVLALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLA 1680
            TILQHWKKCDSWWAKDSPLETKMAVLALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLA
Sbjct: 1621 TILQHWKKCDSWWAKDSPLETKMAVLALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLA 1680

Query: 1681 DTKLDLHLKGQAVTLLPFFTSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYV 1740
            DTKLDLHLKGQAVTLLPFFTSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYV
Sbjct: 1681 DTKLDLHLKGQAVTLLPFFTSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYV 1740

Query: 1741 DCMKKFLDALELSQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLES 1800
            DCMKKFLDALELSQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLES
Sbjct: 1741 DCMKKFLDALELSQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLES 1800

Query: 1801 VYEMFRKDDPRLSFTRQSFVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLKSRFTKLNE 1860
            VYEMFRKDDPRLSFTRQSFVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLKSRFTKLNE
Sbjct: 1801 VYEMFRKDDPRLSFTRQSFVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLKSRFTKLNE 1860

Query: 1861 STFDTQITKKMGYYKILDVMYSRLPKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCY 1920
            STFDTQITKKMGYYKILDVMYSRLPKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCY
Sbjct: 1861 STFDTQITKKMGYYKILDVMYSRLPKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCY 1920

Query: 1921 DAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLLIFEN 1980
            DAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLLIFEN
Sbjct: 1921 DAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLLIFEN 1980

Query: 1981 LIDLKRRYNFPVEVEVPMERKKKYIEIRKEAREAANGDSDGPSYMSSLSYLADSTLSEEM 2040
            LIDLKRRYNFPVEVEVPMERKKKYIEIRKEAREAANGDSDGPSYMSSLSYLADSTLSEEM
Sbjct: 1981 LIDLKRRYNFPVEVEVPMERKKKYIEIRKEAREAANGDSDGPSYMSSLSYLADSTLSEEM 2040

Query: 2041 SQFDFSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTAL 2100
            SQFDFSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTAL
Sbjct: 2041 SQFDFSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTAL 2100

Query: 2101 VKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPY 2160
            VKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPY
Sbjct: 2101 VKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPY 2160

Query: 2161 AKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGLATPTGVPKDEVLANRLLNFLM 2220
            AKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGLATPTGVPKDEVLANRLLNFLM
Sbjct: 2161 AKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGLATPTGVPKDEVLANRLLNFLM 2220

Query: 2221 KHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIV 2280
            KHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIV
Sbjct: 2221 KHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIV 2280

Query: 2281 MANDLPPYDPQCGIQSSEYFQALVNNMSFVRYKEVYAAAAEVLGLILRYVMERKNILEES 2340
            MANDLPPYDPQCGIQSSEYFQALVNNMSFVRYKEVYAAAAEVLGLILRYVMERKNILEES
Sbjct: 2281 MANDLPPYDPQCGIQSSEYFQALVNNMSFVRYKEVYAAAAEVLGLILRYVMERKNILEES 2340

Query: 2341 LCELVAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEV 2400
            LCELVAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEV
Sbjct: 2341 LCELVAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEV 2400

Query: 2401 VLCRVEGMTELYFQLKSKDFVQVMRHRDERQKVCLDIIYKMMPKLKPVELRELLNPVVEF 2460
            VLCRVEGMTELYFQLKSKDFVQVMRHRDERQKVCLDIIYKMMPKLKPVELRELLNPVVEF
Sbjct: 2401 VLCRVEGMTELYFQLKSKDFVQVMRHRDERQKVCLDIIYKMMPKLKPVELRELLNPVVEF 2460

Query: 2461 VSHPSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLII 2520
            VSHPSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLII
Sbjct: 2461 VSHPSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLII 2520

Query: 2521 RNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHPL 2580
            RNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHPL
Sbjct: 2521 RNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHPL 2580

Query: 2581 SECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQQ 2640
            SECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQQ
Sbjct: 2581 SECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQQ 2640

Query: 2641 HDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSDSLLFAHKRSERLQRAPLKSVGPDFG 2700
            HDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSDSLLFAHKRSERLQRAPLKSVGPDFG
Sbjct: 2641 HDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSDSLLFAHKRSERLQRAPLKSVGPDFG 2700

Query: 2701 KKRLGLPGDEVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSEL 2760
            KKRLGLPGDEVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSEL
Sbjct: 2701 KKRLGLPGDEVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSEL 2760

Query: 2761 KMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEMD 2820
            KMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEMD
Sbjct: 2761 KMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEMD 2820

Query: 2821 KFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAVSAGCL 2880
            KFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAVSAGCL
Sbjct: 2821 KFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAVSAGCL 2880

Query: 2881 ASLQQPVGIRLLEEALLRLLPAELPAKRVRGKARLPPDVLRWVELAKLYRSIGEYDVLRG 2940
            ASLQQPVGIRLLEEALLRLLPAELPAKRVRGKARLPPDVLRWVELAKLYRSIGEYDVLRG
Sbjct: 2881 ASLQQPVGIRLLEEALLRLLPAELPAKRVRGKARLPPDVLRWVELAKLYRSIGEYDVLRG 2940

Query: 2941 IFTSEIGTKQITQSALLAEARSDYSEAAKQYDEALNKQDWVDGEPTEAEKDFWELASLDC 3000
            IFTSEIGTKQITQSALLAEARSDYSEAAKQYDEALNKQDWVDGEPTEAEKDFWELASLDC
Sbjct: 2941 IFTSEIGTKQITQSALLAEARSDYSEAAKQYDEALNKQDWVDGEPTEAEKDFWELASLDC 3000

Query: 3001 YNHLAEWKSLEYCSTASIDSENPPDLNKIWSEPFYQETYLPYMIRSKLKLLLQGEADQSL 3060
            YNHLAEWKSLEYCSTASIDSENPPDLNKIWSEPFYQETYLPYMIRSKLKLLLQGEADQSL
Sbjct: 3001 YNHLAEWKSLEYCSTASIDSENPPDLNKIWSEPFYQETYLPYMIRSKLKLLLQGEADQSL 3060

Query: 3061 LTFIDKAMHGELQKAILELHYSQELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVLL 3120
            LTFIDKAMHGELQKAILELHYSQELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVLL
Sbjct: 3061 LTFIDKAMHGELQKAILELHYSQELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVLL 3120

Query: 3121 HQSRLTKLQSVQALTEIQEFISFISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWDD 3180
            HQSRLTKLQSVQALTEIQEFISFISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWDD
Sbjct: 3121 HQSRLTKLQSVQALTEIQEFISFISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWDD 3180

Query: 3181 IITNRCFFLSKIEEKLTPLPEDNSMNVDQDGDPSDRMEVQEQEEDISSLIRSCKFSMKMK 3240
            IITNRCFFLSKIEEKLTPLPEDNSMNVDQDGDPSDRMEVQEQEEDISSLIRSCKFSMKMK
Sbjct: 3181 IITNRCFFLSKIEEKLTPLPEDNSMNVDQDGDPSDRMEVQEQEEDISSLIRSCKFSMKMK 3240

Query: 3241 MIDSARKQNNFSLAMKLLKELHKESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTVL 3300
            MIDSARKQNNFSLAMKLLKELHKESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTVL
Sbjct: 3241 MIDSARKQNNFSLAMKLLKELHKESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTVL 3300

Query: 3301 KTVSLLDENNVSSYLNKNILAFRDQNILLGTTYRIIANALSSEPACLAEIEEDKARRILE 3360
            KTVSLLDENNVSSYLNKNILAFRDQNILLGTTYRIIANALSSEPACLAEIEEDKARRILE
Sbjct: 3301 KTVSLLDENNVSSYLNKNILAFRDQNILLGTTYRIIANALSSEPACLAEIEEDKARRILE 3360

Query: 3361 LSGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFCD 3420
            LSGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFCD
Sbjct: 3361 LSGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFCD 3420

Query: 3421 QQLRKEEENASVTDSAELQAYPALVVEKMLKALKLNSNEARLKFPRLLQIIERYPEETLS 3480
            QQLRKEEENASVTDSAELQAYPALVVEKMLKALKLNSNEARLKFPRLLQIIERYPEETLS
Sbjct: 3421 QQLRKEEENASVTDSAELQAYPALVVEKMLKALKLNSNEARLKFPRLLQIIERYPEETLS 3480

Query: 3481 LMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESYS 3540
            LMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESYS
Sbjct: 3481 LMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESYS 3540

Query: 3541 FKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTPV 3600
            FKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTPV
Sbjct: 3541 FKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTPV 3600

Query: 3601 NKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFND 3660
            NKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFND
Sbjct: 3601 NKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFND 3660

Query: 3661 ITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVRIAG 3720
            ITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVRIAG
Sbjct: 3661 ITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVRIAG 3720

Query: 3721 FDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSAC 3780
            FDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSAC
Sbjct: 3721 FDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSAC 3780

Query: 3781 SQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDVGAYMLMYKGANRTETVTSFR 3840
            SQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDVGAYMLMYKGANRTETVTSFR
Sbjct: 3781 SQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDVGAYMLMYKGANRTETVTSFR 3840

Query: 3841 KRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFMVAM 3900
            KRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFMVAM
Sbjct: 3841 KRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFMVAM 3900

Query: 3901 ETGGVIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKETGLMYSIMVHALRAFR 3960
            ETGGVIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKETGLMYSIMVHALRAFR
Sbjct: 3901 ETGGVIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKETGLMYSIMVHALRAFR 3960

Query: 3961 SDPGLLTNTMDVFVKEPSFDWKNFEQKMLKKGGSWIQEINVAEKNWYPRQKICYAKRKLA 4020
            SDPGLLTNTMDVFVKEPSFDWKNFEQKMLKKGGSWIQEINVAEKNWYPRQKICYAKRKLA
Sbjct: 3961 SDPGLLTNTMDVFVKEPSFDWKNFEQKMLKKGGSWIQEINVAEKNWYPRQKICYAKRKLA 4020

Query: 4021 GANPAVITCDELLLGHEKAPAFRDYVAVARGSKDHNIRAQEPESGLSEETQVKCLMDQAT 4080
            GANPAVITCDELLLGHEKAPAFRDYVAVARGSKDHNIRAQEPESGLSEETQVKCLMDQAT
Sbjct: 4021 GANPAVITCDELLLGHEKAPAFRDYVAVARGSKDHNIRAQEPESGLSEETQVKCLMDQAT 4080

Query: 4081 DPNILGRTWEGWEPWM 4096
            DPNILGRTWEGWEPWM
Sbjct: 4081 DPNILGRTWEGWEPWM 4096


>gi|126032350 protein kinase, DNA-activated, catalytic polypeptide
            isoform 2 [Homo sapiens]
          Length = 4097

 Score = 8147 bits (21139), Expect = 0.0
 Identities = 4092/4097 (99%), Positives = 4094/4097 (99%), Gaps = 1/4097 (0%)

Query: 1    MAGSGAGVRCSLLRLQETLSAADRCGAALAGHQLIRGLGQECVLSSSPAVLALQTSLVFS 60
            MAGSGAGVRCSLLRLQETLSAADRCGAALAGHQLIRGLGQECVLSSSPAVLALQTSLVFS
Sbjct: 1    MAGSGAGVRCSLLRLQETLSAADRCGAALAGHQLIRGLGQECVLSSSPAVLALQTSLVFS 60

Query: 61   RDFGLLVFVRKSLNSIEFRECREEILKFLCIFLEKMGQKIAPYSVEIKNTCTSVYTKDRA 120
            RDFGLLVFVRKSLNSIEFRECREEILKFLCIFLEKMGQKIAPYSVEIKNTCTSVYTKDRA
Sbjct: 61   RDFGLLVFVRKSLNSIEFRECREEILKFLCIFLEKMGQKIAPYSVEIKNTCTSVYTKDRA 120

Query: 121  AKCKIPALDLLIKLLQTFRSSRLMDEFKIGELFSKFYGELALKKKIPDTVLEKVYELLGL 180
            AKCKIPALDLLIKLLQTFRSSRLMDEFKIGELFSKFYGELALKKKIPDTVLEKVYELLGL
Sbjct: 121  AKCKIPALDLLIKLLQTFRSSRLMDEFKIGELFSKFYGELALKKKIPDTVLEKVYELLGL 180

Query: 181  LGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE 240
            LGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE
Sbjct: 181  LGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE 240

Query: 241  DPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKW 300
            DPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKW
Sbjct: 241  DPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKW 300

Query: 301  CAHTNVELKKAALSALESFLKQVSNMVAKNAEMHKNKLQYFMEQFYGIIRNVDSNNKELS 360
            CAHTNVELKKAALSALESFLKQVSNMVAKNAEMHKNKLQYFMEQFYGIIRNVDSNNKELS
Sbjct: 301  CAHTNVELKKAALSALESFLKQVSNMVAKNAEMHKNKLQYFMEQFYGIIRNVDSNNKELS 360

Query: 361  IAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTQTDTGDYRVYQMPSFLQSVASV 420
            IAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTQTDTGD RVYQMPSFLQSVASV
Sbjct: 361  IAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTQTDTGDDRVYQMPSFLQSVASV 420

Query: 421  LLYLDTVPEVYTPVLEHLVVMQIDSFPQYSPKMQLVCCRAIVKVFLALAAKGPVLRNCIS 480
            LLYLDTVPEVYTPVLEHLVVMQIDSFPQYSPKMQLVCCRAIVKVFLALAAKGPVLRNCIS
Sbjct: 421  LLYLDTVPEVYTPVLEHLVVMQIDSFPQYSPKMQLVCCRAIVKVFLALAAKGPVLRNCIS 480

Query: 481  TVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQM 540
            TVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQM
Sbjct: 481  TVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQM 540

Query: 541  MDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGV 600
            MDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGV
Sbjct: 541  MDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGV 600

Query: 601  WMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRL 660
            WMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRL
Sbjct: 601  WMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRL 660

Query: 661  PLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAVKMKQ 720
            PLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAVKMKQ
Sbjct: 661  PLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAVKMKQ 720

Query: 721  YKDELLASCLTFLLSLPHNIIELDVRAYVPALQMAFKLGLSYTPLAEVGLNALEEWSIYI 780
            YKDELLASCLTFLLSLPHNIIELDVRAYVPALQMAFKLGLSYTPLAEVGLNALEEWSIYI
Sbjct: 721  YKDELLASCLTFLLSLPHNIIELDVRAYVPALQMAFKLGLSYTPLAEVGLNALEEWSIYI 780

Query: 781  DRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSRAAQKGFNKVVLKHLKKTKNL 840
            DRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSRAAQKGFNKVVLKHLKKTKNL
Sbjct: 781  DRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSRAAQKGFNKVVLKHLKKTKNL 840

Query: 841  SSNEAISLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDREKRLSFAVPFRE 900
            SSNEAISLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDREKRLSFAVPFRE
Sbjct: 841  SSNEAISLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDREKRLSFAVPFRE 900

Query: 901  MKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGKATQMPEGGQGAPPMYQ 960
            MKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGKATQMPEGGQGAPPMYQ
Sbjct: 901  MKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGKATQMPEGGQGAPPMYQ 960

Query: 961  LYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVSLLEAILDGIVDP 1020
            LYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTV+LLEAILDGIVDP
Sbjct: 961  LYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVALLEAILDGIVDP 1020

Query: 1021 VDSTLRDFCGRCIREFLKWSIKQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASL 1080
            VDSTLRDFCGRCIREFLKWSIKQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASL
Sbjct: 1021 VDSTLRDFCGRCIREFLKWSIKQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASL 1080

Query: 1081 AFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEK 1140
            AFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEK
Sbjct: 1081 AFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEK 1140

Query: 1141 KHVSLNKAKKRRLPRGFPPSASLCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPG 1200
            KHVSLNKAKKRRLPRGFPPSASLCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPG
Sbjct: 1141 KHVSLNKAKKRRLPRGFPPSASLCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPG 1200

Query: 1201 NRSPNLWLKDVLKEEGVSFLINTFEGGGCGQPSGILAQPTLLYLRGPFSLQATLCWLDLL 1260
            NRSPNLWLKDVLKEEGVSFLINTFEGGGCGQPSGILAQPTLLYLRGPFSLQATLCWLDLL
Sbjct: 1201 NRSPNLWLKDVLKEEGVSFLINTFEGGGCGQPSGILAQPTLLYLRGPFSLQATLCWLDLL 1260

Query: 1261 LAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFLESIAMHDIIAAEKCFGTGAAGN 1320
            LAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFLESIAMHDIIAAEKCFGTGAAGN
Sbjct: 1261 LAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFLESIAMHDIIAAEKCFGTGAAGN 1320

Query: 1321 RTSPQEGERYNYSKCTVVVRIMEFTTTLLNTSPEGWKLLKKDLCNTHLMRVLVQTLCEPA 1380
            RTSPQEGERYNYSKCTVVVRIMEFTTTLLNTSPEGWKLLKKDLCNTHLMRVLVQTLCEPA
Sbjct: 1321 RTSPQEGERYNYSKCTVVVRIMEFTTTLLNTSPEGWKLLKKDLCNTHLMRVLVQTLCEPA 1380

Query: 1381 SIGFNIGDVQVMAHLPDVCVNLMKALKMSPYKDILETHLREKITAQSIEELCAVNLYGPD 1440
            SIGFNIGDVQVMAHLPDVCVNLMKALKMSPYKDILETHLREKITAQSIEELCAVNLYGPD
Sbjct: 1381 SIGFNIGDVQVMAHLPDVCVNLMKALKMSPYKDILETHLREKITAQSIEELCAVNLYGPD 1440

Query: 1441 AQVDRSRLAAVVSACKQLHRAGLLHNILPSQSTDLHHSVGTELLSLVYKGIAPGDERQCL 1500
            AQVDRSRLAAVVSACKQLHRAGLLHNILPSQSTDLHHSVGTELLSLVYKGIAPGDERQCL
Sbjct: 1441 AQVDRSRLAAVVSACKQLHRAGLLHNILPSQSTDLHHSVGTELLSLVYKGIAPGDERQCL 1500

Query: 1501 PSLDLSCKQLASGLLELAFAFGGLCERLVSLLLNPAVLSTASLGSSQGSVIHFSHGEYFY 1560
            PSLDLSCKQLASGLLELAFAFGGLCERLVSLLLNPAVLSTASLGSSQGSVIHFSHGEYFY
Sbjct: 1501 PSLDLSCKQLASGLLELAFAFGGLCERLVSLLLNPAVLSTASLGSSQGSVIHFSHGEYFY 1560

Query: 1561 SLFSETINTELLKNLDLAVLELMQSSVDNTKMVSAVLNGMLDQSFRERANQKHQGLKLAT 1620
            SLFSETINTELLKNLDLAVLELMQSSVDNTKMVSAVLNGMLDQSFRERANQKHQGLKLAT
Sbjct: 1561 SLFSETINTELLKNLDLAVLELMQSSVDNTKMVSAVLNGMLDQSFRERANQKHQGLKLAT 1620

Query: 1621 TILQHWKKCDSWWAKDSPLETKMAVLALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLA 1680
            TILQHWKKCDSWWAKDSPLETKMAVLALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLA
Sbjct: 1621 TILQHWKKCDSWWAKDSPLETKMAVLALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLA 1680

Query: 1681 DTKLDLHLKGQAVTLLPFFTSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYV 1740
            DTKLDLHLKGQAVTLLPFFTSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYV
Sbjct: 1681 DTKLDLHLKGQAVTLLPFFTSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYV 1740

Query: 1741 DCMKKFLDALELSQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLES 1800
            DCMKKFLDALELSQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLES
Sbjct: 1741 DCMKKFLDALELSQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLES 1800

Query: 1801 VYEMFRKDDPRLSFTRQSFVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLKSRFTKLNE 1860
            VYEMFRKDDPRLSFTRQSFVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLKSRFTKLNE
Sbjct: 1801 VYEMFRKDDPRLSFTRQSFVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLKSRFTKLNE 1860

Query: 1861 STFDTQITKKMGYYKILDVMYSRLPKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCY 1920
            STFDTQITKKMGYYKILDVMYSRLPKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCY
Sbjct: 1861 STFDTQITKKMGYYKILDVMYSRLPKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCY 1920

Query: 1921 DAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLLIFEN 1980
            DAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLLIFEN
Sbjct: 1921 DAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLLIFEN 1980

Query: 1981 LIDLKRRYNFPVEVEVPMERKKKYIEIRKEAREAANGDSDGPSYMSSLSYLADSTLSEEM 2040
            LIDLKRRYNFPVEVEVPMERKKKYIEIRKEAREAANGDSDGPSYMSSLSYLADSTLSEEM
Sbjct: 1981 LIDLKRRYNFPVEVEVPMERKKKYIEIRKEAREAANGDSDGPSYMSSLSYLADSTLSEEM 2040

Query: 2041 SQFDFSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTAL 2100
            SQFDFSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTAL
Sbjct: 2041 SQFDFSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTAL 2100

Query: 2101 VKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPY 2160
            VKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPY
Sbjct: 2101 VKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPY 2160

Query: 2161 AKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGLATPTGVPKDEVLANRLLNFLM 2220
            AKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGLATPTGVPKDEVLANRLLNFLM
Sbjct: 2161 AKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGLATPTGVPKDEVLANRLLNFLM 2220

Query: 2221 KHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIV 2280
            KHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIV
Sbjct: 2221 KHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIV 2280

Query: 2281 MANDLPPYDPQCGIQSSEYFQALVNNMSFVRYKEVYAAAAEVLGLILRYVMERKNILEES 2340
            MANDLPPYDPQCGIQSSEYFQALVNNMSFVRYKEVYAAAAEVLGLILRYVMERKNILEES
Sbjct: 2281 MANDLPPYDPQCGIQSSEYFQALVNNMSFVRYKEVYAAAAEVLGLILRYVMERKNILEES 2340

Query: 2341 LCELVAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEV 2400
            LCELVAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEV
Sbjct: 2341 LCELVAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEV 2400

Query: 2401 VLCRVEGMTELYFQLKSKDFVQVMRHR-DERQKVCLDIIYKMMPKLKPVELRELLNPVVE 2459
            VLCRVEGMTELYFQLKSKDFVQVMRHR DERQKVCLDIIYKMMPKLKPVELRELLNPVVE
Sbjct: 2401 VLCRVEGMTELYFQLKSKDFVQVMRHRDDERQKVCLDIIYKMMPKLKPVELRELLNPVVE 2460

Query: 2460 FVSHPSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLI 2519
            FVSHPSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLI
Sbjct: 2461 FVSHPSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLI 2520

Query: 2520 IRNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHP 2579
            IRNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHP
Sbjct: 2521 IRNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHP 2580

Query: 2580 LSECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQ 2639
            LSECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQ
Sbjct: 2581 LSECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQ 2640

Query: 2640 QHDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSDSLLFAHKRSERLQRAPLKSVGPDF 2699
            QHDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSDSLLFAHKRSERLQRAPLKSVGPDF
Sbjct: 2641 QHDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSDSLLFAHKRSERLQRAPLKSVGPDF 2700

Query: 2700 GKKRLGLPGDEVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSE 2759
            GKKRLGLPGDEVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSE
Sbjct: 2701 GKKRLGLPGDEVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSE 2760

Query: 2760 LKMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEM 2819
            LKMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEM
Sbjct: 2761 LKMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEM 2820

Query: 2820 DKFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAVSAGC 2879
            DKFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAVSAGC
Sbjct: 2821 DKFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAVSAGC 2880

Query: 2880 LASLQQPVGIRLLEEALLRLLPAELPAKRVRGKARLPPDVLRWVELAKLYRSIGEYDVLR 2939
            LASLQQPVGIRLLEEALLRLLPAELPAKRVRGKARLPPDVLRWVELAKLYRSIGEYDVLR
Sbjct: 2881 LASLQQPVGIRLLEEALLRLLPAELPAKRVRGKARLPPDVLRWVELAKLYRSIGEYDVLR 2940

Query: 2940 GIFTSEIGTKQITQSALLAEARSDYSEAAKQYDEALNKQDWVDGEPTEAEKDFWELASLD 2999
            GIFTSEIGTKQITQSALLAEARSDYSEAAKQYDEALNKQDWVDGEPTEAEKDFWELASLD
Sbjct: 2941 GIFTSEIGTKQITQSALLAEARSDYSEAAKQYDEALNKQDWVDGEPTEAEKDFWELASLD 3000

Query: 3000 CYNHLAEWKSLEYCSTASIDSENPPDLNKIWSEPFYQETYLPYMIRSKLKLLLQGEADQS 3059
            CYNHLAEWKSLEYCSTASIDSENPPDLNKIWSEPFYQETYLPYMIRSKLKLLLQGEADQS
Sbjct: 3001 CYNHLAEWKSLEYCSTASIDSENPPDLNKIWSEPFYQETYLPYMIRSKLKLLLQGEADQS 3060

Query: 3060 LLTFIDKAMHGELQKAILELHYSQELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVL 3119
            LLTFIDKAMHGELQKAILELHYSQELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVL
Sbjct: 3061 LLTFIDKAMHGELQKAILELHYSQELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVL 3120

Query: 3120 LHQSRLTKLQSVQALTEIQEFISFISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWD 3179
            LHQSRLTKLQSVQALTEIQEFISFISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWD
Sbjct: 3121 LHQSRLTKLQSVQALTEIQEFISFISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWD 3180

Query: 3180 DIITNRCFFLSKIEEKLTPLPEDNSMNVDQDGDPSDRMEVQEQEEDISSLIRSCKFSMKM 3239
            DIITNRCFFLSKIEEKLTPLPEDNSMNVDQDGDPSDRMEVQEQEEDISSLIRSCKFSMKM
Sbjct: 3181 DIITNRCFFLSKIEEKLTPLPEDNSMNVDQDGDPSDRMEVQEQEEDISSLIRSCKFSMKM 3240

Query: 3240 KMIDSARKQNNFSLAMKLLKELHKESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTV 3299
            KMIDSARKQNNFSLAMKLLKELHKESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTV
Sbjct: 3241 KMIDSARKQNNFSLAMKLLKELHKESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTV 3300

Query: 3300 LKTVSLLDENNVSSYLNKNILAFRDQNILLGTTYRIIANALSSEPACLAEIEEDKARRIL 3359
            LKTVSLLDENNVSSYL+KNILAFRDQNILLGTTYRIIANALSSEPACLAEIEEDKARRIL
Sbjct: 3301 LKTVSLLDENNVSSYLSKNILAFRDQNILLGTTYRIIANALSSEPACLAEIEEDKARRIL 3360

Query: 3360 ELSGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFC 3419
            ELSGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFC
Sbjct: 3361 ELSGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFC 3420

Query: 3420 DQQLRKEEENASVTDSAELQAYPALVVEKMLKALKLNSNEARLKFPRLLQIIERYPEETL 3479
            DQQLRKEEENASV DSAELQAYPALVVEKMLKALKLNSNEARLKFPRLLQIIERYPEETL
Sbjct: 3421 DQQLRKEEENASVIDSAELQAYPALVVEKMLKALKLNSNEARLKFPRLLQIIERYPEETL 3480

Query: 3480 SLMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESY 3539
            SLMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESY
Sbjct: 3481 SLMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESY 3540

Query: 3540 SFKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTP 3599
            SFKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTP
Sbjct: 3541 SFKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTP 3600

Query: 3600 VNKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFN 3659
            VNKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFN
Sbjct: 3601 VNKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFN 3660

Query: 3660 DITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVRIA 3719
            DITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVRIA
Sbjct: 3661 DITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVRIA 3720

Query: 3720 GFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSA 3779
            GFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSA
Sbjct: 3721 GFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSA 3780

Query: 3780 CSQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDVGAYMLMYKGANRTETVTSF 3839
            CSQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDVGAYMLMYKGANRTETVTSF
Sbjct: 3781 CSQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDVGAYMLMYKGANRTETVTSF 3840

Query: 3840 RKRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFMVA 3899
            RKRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFMVA
Sbjct: 3841 RKRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFMVA 3900

Query: 3900 METGGVIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKETGLMYSIMVHALRAF 3959
            METGGVIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKETGLMYSIMVHALRAF
Sbjct: 3901 METGGVIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKETGLMYSIMVHALRAF 3960

Query: 3960 RSDPGLLTNTMDVFVKEPSFDWKNFEQKMLKKGGSWIQEINVAEKNWYPRQKICYAKRKL 4019
            RSDPGLLTNTMDVFVKEPSFDWKNFEQKMLKKGGSWIQEINVAEKNWYPRQKICYAKRKL
Sbjct: 3961 RSDPGLLTNTMDVFVKEPSFDWKNFEQKMLKKGGSWIQEINVAEKNWYPRQKICYAKRKL 4020

Query: 4020 AGANPAVITCDELLLGHEKAPAFRDYVAVARGSKDHNIRAQEPESGLSEETQVKCLMDQA 4079
            AGANPAVITCDELLLGHEKAPAFRDYVAVARGSKDHNIRAQEPESGLSEETQVKCLMDQA
Sbjct: 4021 AGANPAVITCDELLLGHEKAPAFRDYVAVARGSKDHNIRAQEPESGLSEETQVKCLMDQA 4080

Query: 4080 TDPNILGRTWEGWEPWM 4096
            TDPNILGRTWEGWEPWM
Sbjct: 4081 TDPNILGRTWEGWEPWM 4097


>gi|13654237 protein kinase, DNA-activated, catalytic polypeptide
            isoform 1 [Homo sapiens]
          Length = 4128

 Score = 8131 bits (21097), Expect = 0.0
 Identities = 4092/4128 (99%), Positives = 4094/4128 (99%), Gaps = 32/4128 (0%)

Query: 1    MAGSGAGVRCSLLRLQETLSAADRCGAALAGHQLIRGLGQECVLSSSPAVLALQTSLVFS 60
            MAGSGAGVRCSLLRLQETLSAADRCGAALAGHQLIRGLGQECVLSSSPAVLALQTSLVFS
Sbjct: 1    MAGSGAGVRCSLLRLQETLSAADRCGAALAGHQLIRGLGQECVLSSSPAVLALQTSLVFS 60

Query: 61   RDFGLLVFVRKSLNSIEFRECREEILKFLCIFLEKMGQKIAPYSVEIKNTCTSVYTKDRA 120
            RDFGLLVFVRKSLNSIEFRECREEILKFLCIFLEKMGQKIAPYSVEIKNTCTSVYTKDRA
Sbjct: 61   RDFGLLVFVRKSLNSIEFRECREEILKFLCIFLEKMGQKIAPYSVEIKNTCTSVYTKDRA 120

Query: 121  AKCKIPALDLLIKLLQTFRSSRLMDEFKIGELFSKFYGELALKKKIPDTVLEKVYELLGL 180
            AKCKIPALDLLIKLLQTFRSSRLMDEFKIGELFSKFYGELALKKKIPDTVLEKVYELLGL
Sbjct: 121  AKCKIPALDLLIKLLQTFRSSRLMDEFKIGELFSKFYGELALKKKIPDTVLEKVYELLGL 180

Query: 181  LGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE 240
            LGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE
Sbjct: 181  LGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE 240

Query: 241  DPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKW 300
            DPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKW
Sbjct: 241  DPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKW 300

Query: 301  CAHTNVELKKAALSALESFLKQVSNMVAKNAEMHKNKLQYFMEQFYGIIRNVDSNNKELS 360
            CAHTNVELKKAALSALESFLKQVSNMVAKNAEMHKNKLQYFMEQFYGIIRNVDSNNKELS
Sbjct: 301  CAHTNVELKKAALSALESFLKQVSNMVAKNAEMHKNKLQYFMEQFYGIIRNVDSNNKELS 360

Query: 361  IAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTQTDTGDYRVYQMPSFLQSVASV 420
            IAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTQTDTGD RVYQMPSFLQSVASV
Sbjct: 361  IAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTQTDTGDDRVYQMPSFLQSVASV 420

Query: 421  LLYLDTVPEVYTPVLEHLVVMQIDSFPQYSPKMQLVCCRAIVKVFLALAAKGPVLRNCIS 480
            LLYLDTVPEVYTPVLEHLVVMQIDSFPQYSPKMQLVCCRAIVKVFLALAAKGPVLRNCIS
Sbjct: 421  LLYLDTVPEVYTPVLEHLVVMQIDSFPQYSPKMQLVCCRAIVKVFLALAAKGPVLRNCIS 480

Query: 481  TVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQM 540
            TVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQM
Sbjct: 481  TVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQM 540

Query: 541  MDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGV 600
            MDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGV
Sbjct: 541  MDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGV 600

Query: 601  WMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRL 660
            WMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRL
Sbjct: 601  WMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRL 660

Query: 661  PLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAVKMKQ 720
            PLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAVKMKQ
Sbjct: 661  PLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAVKMKQ 720

Query: 721  YKDELLASCLTFLLSLPHNIIELDVRAYVPALQMAFKLGLSYTPLAEVGLNALEEWSIYI 780
            YKDELLASCLTFLLSLPHNIIELDVRAYVPALQMAFKLGLSYTPLAEVGLNALEEWSIYI
Sbjct: 721  YKDELLASCLTFLLSLPHNIIELDVRAYVPALQMAFKLGLSYTPLAEVGLNALEEWSIYI 780

Query: 781  DRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSRAAQKGFNKVVLKHLKKTKNL 840
            DRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSRAAQKGFNKVVLKHLKKTKNL
Sbjct: 781  DRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSRAAQKGFNKVVLKHLKKTKNL 840

Query: 841  SSNEAISLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDREKRLSFAVPFRE 900
            SSNEAISLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDREKRLSFAVPFRE
Sbjct: 841  SSNEAISLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDREKRLSFAVPFRE 900

Query: 901  MKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGKATQMPEGGQGAPPMYQ 960
            MKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGKATQMPEGGQGAPPMYQ
Sbjct: 901  MKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGKATQMPEGGQGAPPMYQ 960

Query: 961  LYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVSLLEAILDGIVDP 1020
            LYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTV+LLEAILDGIVDP
Sbjct: 961  LYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVALLEAILDGIVDP 1020

Query: 1021 VDSTLRDFCGRCIREFLKWSIKQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASL 1080
            VDSTLRDFCGRCIREFLKWSIKQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASL
Sbjct: 1021 VDSTLRDFCGRCIREFLKWSIKQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASL 1080

Query: 1081 AFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEK 1140
            AFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEK
Sbjct: 1081 AFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEK 1140

Query: 1141 KHVSLNKAKKRRLPRGFPPSASLCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPG 1200
            KHVSLNKAKKRRLPRGFPPSASLCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPG
Sbjct: 1141 KHVSLNKAKKRRLPRGFPPSASLCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPG 1200

Query: 1201 NRSPNLWLKDVLKEEGVSFLINTFEGGGCGQPSGILAQPTLLYLRGPFSLQATLCWLDLL 1260
            NRSPNLWLKDVLKEEGVSFLINTFEGGGCGQPSGILAQPTLLYLRGPFSLQATLCWLDLL
Sbjct: 1201 NRSPNLWLKDVLKEEGVSFLINTFEGGGCGQPSGILAQPTLLYLRGPFSLQATLCWLDLL 1260

Query: 1261 LAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFLESIAMHDIIAAEKCFGTGAAGN 1320
            LAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFLESIAMHDIIAAEKCFGTGAAGN
Sbjct: 1261 LAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFLESIAMHDIIAAEKCFGTGAAGN 1320

Query: 1321 RTSPQEGERYNYSKCTVVVRIMEFTTTLLNTSPEGWKLLKKDLCNTHLMRVLVQTLCEPA 1380
            RTSPQEGERYNYSKCTVVVRIMEFTTTLLNTSPEGWKLLKKDLCNTHLMRVLVQTLCEPA
Sbjct: 1321 RTSPQEGERYNYSKCTVVVRIMEFTTTLLNTSPEGWKLLKKDLCNTHLMRVLVQTLCEPA 1380

Query: 1381 SIGFNIGDVQVMAHLPDVCVNLMKALKMSPYKDILETHLREKITAQSIEELCAVNLYGPD 1440
            SIGFNIGDVQVMAHLPDVCVNLMKALKMSPYKDILETHLREKITAQSIEELCAVNLYGPD
Sbjct: 1381 SIGFNIGDVQVMAHLPDVCVNLMKALKMSPYKDILETHLREKITAQSIEELCAVNLYGPD 1440

Query: 1441 AQVDRSRLAAVVSACKQLHRAGLLHNILPSQSTDLHHSVGTELLSLVYKGIAPGDERQCL 1500
            AQVDRSRLAAVVSACKQLHRAGLLHNILPSQSTDLHHSVGTELLSLVYKGIAPGDERQCL
Sbjct: 1441 AQVDRSRLAAVVSACKQLHRAGLLHNILPSQSTDLHHSVGTELLSLVYKGIAPGDERQCL 1500

Query: 1501 PSLDLSCKQLASGLLELAFAFGGLCERLVSLLLNPAVLSTASLGSSQGSVIHFSHGEYFY 1560
            PSLDLSCKQLASGLLELAFAFGGLCERLVSLLLNPAVLSTASLGSSQGSVIHFSHGEYFY
Sbjct: 1501 PSLDLSCKQLASGLLELAFAFGGLCERLVSLLLNPAVLSTASLGSSQGSVIHFSHGEYFY 1560

Query: 1561 SLFSETINTELLKNLDLAVLELMQSSVDNTKMVSAVLNGMLDQSFRERANQKHQGLKLAT 1620
            SLFSETINTELLKNLDLAVLELMQSSVDNTKMVSAVLNGMLDQSFRERANQKHQGLKLAT
Sbjct: 1561 SLFSETINTELLKNLDLAVLELMQSSVDNTKMVSAVLNGMLDQSFRERANQKHQGLKLAT 1620

Query: 1621 TILQHWKKCDSWWAKDSPLETKMAVLALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLA 1680
            TILQHWKKCDSWWAKDSPLETKMAVLALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLA
Sbjct: 1621 TILQHWKKCDSWWAKDSPLETKMAVLALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLA 1680

Query: 1681 DTKLDLHLKGQAVTLLPFFTSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYV 1740
            DTKLDLHLKGQAVTLLPFFTSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYV
Sbjct: 1681 DTKLDLHLKGQAVTLLPFFTSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYV 1740

Query: 1741 DCMKKFLDALELSQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLES 1800
            DCMKKFLDALELSQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLES
Sbjct: 1741 DCMKKFLDALELSQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLES 1800

Query: 1801 VYEMFRKDDPRLSFTRQSFVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLKSRFTKLNE 1860
            VYEMFRKDDPRLSFTRQSFVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLKSRFTKLNE
Sbjct: 1801 VYEMFRKDDPRLSFTRQSFVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLKSRFTKLNE 1860

Query: 1861 STFDTQITKKMGYYKILDVMYSRLPKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCY 1920
            STFDTQITKKMGYYKILDVMYSRLPKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCY
Sbjct: 1861 STFDTQITKKMGYYKILDVMYSRLPKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCY 1920

Query: 1921 DAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLLIFEN 1980
            DAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLLIFEN
Sbjct: 1921 DAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLLIFEN 1980

Query: 1981 LIDLKRRYNFPVEVEVPMERKKKYIEIRKEAREAANGDSDGPSYMSSLSYLADSTLSEEM 2040
            LIDLKRRYNFPVEVEVPMERKKKYIEIRKEAREAANGDSDGPSYMSSLSYLADSTLSEEM
Sbjct: 1981 LIDLKRRYNFPVEVEVPMERKKKYIEIRKEAREAANGDSDGPSYMSSLSYLADSTLSEEM 2040

Query: 2041 SQFDFSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTAL 2100
            SQFDFSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTAL
Sbjct: 2041 SQFDFSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTAL 2100

Query: 2101 VKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPY 2160
            VKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPY
Sbjct: 2101 VKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPY 2160

Query: 2161 AKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGLATPTGVPKDEVLANRLLNFLM 2220
            AKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGLATPTGVPKDEVLANRLLNFLM
Sbjct: 2161 AKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGLATPTGVPKDEVLANRLLNFLM 2220

Query: 2221 KHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIV 2280
            KHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIV
Sbjct: 2221 KHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIV 2280

Query: 2281 MANDLPPYDPQCGIQSSEYFQALVNNMSFVRYKEVYAAAAEVLGLILRYVMERKNILEES 2340
            MANDLPPYDPQCGIQSSEYFQALVNNMSFVRYKEVYAAAAEVLGLILRYVMERKNILEES
Sbjct: 2281 MANDLPPYDPQCGIQSSEYFQALVNNMSFVRYKEVYAAAAEVLGLILRYVMERKNILEES 2340

Query: 2341 LCELVAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEV 2400
            LCELVAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEV
Sbjct: 2341 LCELVAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEV 2400

Query: 2401 VLCRVEGMTELYFQLKSKDFVQVMRHRD-ERQKVCLDIIYKMMPKLKPVELRELLNPVVE 2459
            VLCRVEGMTELYFQLKSKDFVQVMRHRD ERQKVCLDIIYKMMPKLKPVELRELLNPVVE
Sbjct: 2401 VLCRVEGMTELYFQLKSKDFVQVMRHRDDERQKVCLDIIYKMMPKLKPVELRELLNPVVE 2460

Query: 2460 FVSHPSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLI 2519
            FVSHPSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLI
Sbjct: 2461 FVSHPSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLI 2520

Query: 2520 IRNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHP 2579
            IRNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHP
Sbjct: 2521 IRNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHP 2580

Query: 2580 LSECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQ 2639
            LSECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQ
Sbjct: 2581 LSECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQ 2640

Query: 2640 QHDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSDSLLFAHKRSERLQRAPLKSVGPDF 2699
            QHDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSDSLLFAHKRSERLQRAPLKSVGPDF
Sbjct: 2641 QHDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSDSLLFAHKRSERLQRAPLKSVGPDF 2700

Query: 2700 GKKRLGLPGDEVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSE 2759
            GKKRLGLPGDEVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSE
Sbjct: 2701 GKKRLGLPGDEVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSE 2760

Query: 2760 LKMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEM 2819
            LKMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEM
Sbjct: 2761 LKMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEM 2820

Query: 2820 DKFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAVSAGC 2879
            DKFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAVSAGC
Sbjct: 2821 DKFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAVSAGC 2880

Query: 2880 LASLQQPVGIRLLEEALLRLLPAELPAKRVRGKARLPPDVLRWVELAKLYRSIGEYDVLR 2939
            LASLQQPVGIRLLEEALLRLLPAELPAKRVRGKARLPPDVLRWVELAKLYRSIGEYDVLR
Sbjct: 2881 LASLQQPVGIRLLEEALLRLLPAELPAKRVRGKARLPPDVLRWVELAKLYRSIGEYDVLR 2940

Query: 2940 GIFTSEIGTKQITQSALLAEARSDYSEAAKQYDEALNKQDWVDGEPTEAEKDFWELASLD 2999
            GIFTSEIGTKQITQSALLAEARSDYSEAAKQYDEALNKQDWVDGEPTEAEKDFWELASLD
Sbjct: 2941 GIFTSEIGTKQITQSALLAEARSDYSEAAKQYDEALNKQDWVDGEPTEAEKDFWELASLD 3000

Query: 3000 CYNHLAEWKSLEYCSTASIDSENPPDLNKIWSEPFYQETYLPYMIRSKLKLLLQGEADQS 3059
            CYNHLAEWKSLEYCSTASIDSENPPDLNKIWSEPFYQETYLPYMIRSKLKLLLQGEADQS
Sbjct: 3001 CYNHLAEWKSLEYCSTASIDSENPPDLNKIWSEPFYQETYLPYMIRSKLKLLLQGEADQS 3060

Query: 3060 LLTFIDKAMHGELQKAILELHYSQELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVL 3119
            LLTFIDKAMHGELQKAILELHYSQELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVL
Sbjct: 3061 LLTFIDKAMHGELQKAILELHYSQELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVL 3120

Query: 3120 LHQSRLTKLQSVQALTEIQEFISFISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWD 3179
            LHQSRLTKLQSVQALTEIQEFISFISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWD
Sbjct: 3121 LHQSRLTKLQSVQALTEIQEFISFISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWD 3180

Query: 3180 DIITNRCFFLSKIEEKLTPLPEDNSMNVDQDGDPSDRMEVQEQEEDISSLIRSCKFSMKM 3239
            DIITNRCFFLSKIEEKLTPLPEDNSMNVDQDGDPSDRMEVQEQEEDISSLIRSCKFSMKM
Sbjct: 3181 DIITNRCFFLSKIEEKLTPLPEDNSMNVDQDGDPSDRMEVQEQEEDISSLIRSCKFSMKM 3240

Query: 3240 KMIDSARKQNNFSLAMKLLKELHKESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTV 3299
            KMIDSARKQNNFSLAMKLLKELHKESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTV
Sbjct: 3241 KMIDSARKQNNFSLAMKLLKELHKESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTV 3300

Query: 3300 LKTVSLLDENNVSSYLNKNILAFRDQNILLGTTYRIIANALSSEPACLAEIEEDKARRIL 3359
            LKTVSLLDENNVSSYL+KNILAFRDQNILLGTTYRIIANALSSEPACLAEIEEDKARRIL
Sbjct: 3301 LKTVSLLDENNVSSYLSKNILAFRDQNILLGTTYRIIANALSSEPACLAEIEEDKARRIL 3360

Query: 3360 ELSGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFC 3419
            ELSGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFC
Sbjct: 3361 ELSGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFC 3420

Query: 3420 DQQLRKEEENASVTDSAELQAYPALVVEKMLKALKLNSNEARLKFPRLLQIIERYPEETL 3479
            DQQLRKEEENASV DSAELQAYPALVVEKMLKALKLNSNEARLKFPRLLQIIERYPEETL
Sbjct: 3421 DQQLRKEEENASVIDSAELQAYPALVVEKMLKALKLNSNEARLKFPRLLQIIERYPEETL 3480

Query: 3480 SLMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESY 3539
            SLMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESY
Sbjct: 3481 SLMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESY 3540

Query: 3540 SFKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTP 3599
            SFKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTP
Sbjct: 3541 SFKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTP 3600

Query: 3600 VNKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFN 3659
            VNKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFN
Sbjct: 3601 VNKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFN 3660

Query: 3660 DITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVRIA 3719
            DITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVRIA
Sbjct: 3661 DITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVRIA 3720

Query: 3720 GFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSA 3779
            GFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSA
Sbjct: 3721 GFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSA 3780

Query: 3780 CSQRALQLRTYSVVPMTS-------------------------------SDPRAPPCEYK 3808
            CSQRALQLRTYSVVPMTS                               SDPRAPPCEYK
Sbjct: 3781 CSQRALQLRTYSVVPMTSRLGLIEWLENTVTLKDLLLNTMSQEEKAAYLSDPRAPPCEYK 3840

Query: 3809 DWLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLAL 3868
            DWLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLAL
Sbjct: 3841 DWLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLAL 3900

Query: 3869 RSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMP 3928
            RSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMP
Sbjct: 3901 RSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMP 3960

Query: 3929 FRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKM 3988
            FRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKM
Sbjct: 3961 FRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKM 4020

Query: 3989 LKKGGSWIQEINVAEKNWYPRQKICYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAV 4048
            LKKGGSWIQEINVAEKNWYPRQKICYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAV
Sbjct: 4021 LKKGGSWIQEINVAEKNWYPRQKICYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAV 4080

Query: 4049 ARGSKDHNIRAQEPESGLSEETQVKCLMDQATDPNILGRTWEGWEPWM 4096
            ARGSKDHNIRAQEPESGLSEETQVKCLMDQATDPNILGRTWEGWEPWM
Sbjct: 4081 ARGSKDHNIRAQEPESGLSEETQVKCLMDQATDPNILGRTWEGWEPWM 4128


>gi|157266317 ataxia telangiectasia and Rad3 related protein [Homo
            sapiens]
          Length = 2644

 Score =  142 bits (357), Expect = 9e-33
 Identities = 109/416 (26%), Positives = 178/416 (42%), Gaps = 83/416 (19%)

Query: 3709 KPLPEYHVRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQ 3768
            +P P +   IAGFD+ V ++ASL++PK+I ++G D + +  + K  +DLR+D R+ +   
Sbjct: 2284 EPFPGHWAYIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNS 2343

Query: 3769 VMNGILAQDSACSQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDV-------- 3820
            ++N  L +D+   +R L +RTY+V+P+         C   +W+   +G   +        
Sbjct: 2344 LINKCLRKDAESRRRELHIRTYAVIPLNDE------CGIIEWVNNTAGLRPILTKLYKEK 2397

Query: 3821 GAYM--------LMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLALRSHF 3872
            G YM        ++ K A  +E +  FR+        +    F+R    P ++ + RS +
Sbjct: 2398 GVYMTGKELRQCMLPKSAALSEKLKVFREFLLPRHPPIFHEWFLRTFPDPTSWYSSRSAY 2457

Query: 3873 ASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMPFRLT 3932
              S A++ +  +ILG+GDRH  N +    TG  + +DF   F     F  VPE++PFRLT
Sbjct: 2458 CRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGETF-EVPEIVPFRLT 2516

Query: 3933 RQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKMLKKG 3992
               +N M PM   GL        +R  R     L + +  F+ +P  +W     K +K  
Sbjct: 2517 HNMVNGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEW----SKPVK-- 2570

Query: 3993 GSWIQEINVAEKNWYPRQKICYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAVARGS 4052
                                                      GH KAP       V   +
Sbjct: 2571 ------------------------------------------GHSKAPLNETGEVVNEKA 2588

Query: 4053 KDHNIRAQEPESG------------LSEETQVKCLMDQATDPNILGRTWEGWEPWM 4096
            K H +  ++   G            LS E  V  L+ +ATD N+L + + GW P+M
Sbjct: 2589 KTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEATDENLLCQMYLGWTPYM 2644


>gi|169165926 PREDICTED: similar to ataxia telangiectasia and Rad3
            related protein, partial [Homo sapiens]
          Length = 386

 Score =  142 bits (357), Expect = 9e-33
 Identities = 109/416 (26%), Positives = 178/416 (42%), Gaps = 83/416 (19%)

Query: 3709 KPLPEYHVRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQ 3768
            +P P +   IAGFD+ V ++ASL++PK+I ++G D + +  + K  +DLR+D R+ +   
Sbjct: 26   EPFPGHWAYIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNS 85

Query: 3769 VMNGILAQDSACSQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDV-------- 3820
            ++N  L +D+   +R L +RTY+V+P+         C   +W+   +G   +        
Sbjct: 86   LINKCLRKDAESRRRELHIRTYAVIPLNDE------CGIIEWVNNTAGLRPILTKLYKEK 139

Query: 3821 GAYM--------LMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLALRSHF 3872
            G YM        ++ K A  +E +  FR+        +    F+R    P ++ + RS +
Sbjct: 140  GVYMTGKELRQCMLPKSAALSEKLKVFREFLLPRHPPIFHEWFLRTFPDPTSWYSSRSAY 199

Query: 3873 ASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMPFRLT 3932
              S A++ +  +ILG+GDRH  N +    TG  + +DF   F     F  VPE++PFRLT
Sbjct: 200  CRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGETF-EVPEIVPFRLT 258

Query: 3933 RQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKMLKKG 3992
               +N M PM   GL        +R  R     L + +  F+ +P  +W     K +K  
Sbjct: 259  HNMVNGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEW----SKPVK-- 312

Query: 3993 GSWIQEINVAEKNWYPRQKICYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAVARGS 4052
                                                      GH KAP       V   +
Sbjct: 313  ------------------------------------------GHSKAPLNETGEVVNEKA 330

Query: 4053 KDHNIRAQEPESG------------LSEETQVKCLMDQATDPNILGRTWEGWEPWM 4096
            K H +  ++   G            LS E  V  L+ +ATD N+L + + GW P+M
Sbjct: 331  KTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEATDENLLCQMYLGWTPYM 386


>gi|4826730 FK506 binding protein 12-rapamycin associated protein 1
            [Homo sapiens]
          Length = 2549

 Score =  140 bits (352), Expect = 3e-32
 Identities = 127/526 (24%), Positives = 239/526 (45%), Gaps = 48/526 (9%)

Query: 3486 ISSVPCWQFISW---ISHMVALLDKDQAVA---VQHSVEEITDNYPQAIVYPFIISSESY 3539
            +  V   Q  +W   I  ++A +D  + +    +   + +I   +PQA++YP  ++S+S 
Sbjct: 1924 VEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKST 1983

Query: 3540 SFKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTP 3599
            +    +  +K  + +    + L     +Q  +   ++L    +L+ +  ++   E ++  
Sbjct: 1984 TTARHNAANKILKNMCEHSNTL-----VQQAMMVSEELIRVAILWHEMWHEGLEEASRLY 2038

Query: 3600 VNKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGK------EFDKHFGKGGSKLLRM 3653
              ++N++ M+E +       +          F Q +G+      E+ + + K G+     
Sbjct: 2039 FGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGN----- 2093

Query: 3654 KLSDFNDITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRN-ELEIPGQYDGRGKPLP 3712
             + D     ++      + SK    L          K+   R+ EL +PG YD   +P+ 
Sbjct: 2094 -VKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPN-QPI- 2150

Query: 3713 EYHVRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNG 3772
               +RI      + V+ S +RP+++ + G +  E  FL+KG EDLRQD+RV QLF ++N 
Sbjct: 2151 ---IRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNT 2207

Query: 3773 ILAQDSACSQRALQLRTYSVVPMTSSDPR---APPCE-----YKDWLTK----MSGKHDV 3820
            +LA D    ++ L ++ Y+V+P++++       P C+      +D+  K    ++ +H +
Sbjct: 2208 LLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRI 2267

Query: 3821 GAYMLM-YKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALI 3879
               M   Y      + V  F    +    D L +     S S E +   R+++  S A++
Sbjct: 2268 MLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVM 2327

Query: 3880 CISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLM 3939
             +  +ILG+GDRH +N M+   +G ++ IDFG  F  A      PE +PFRLTR   N  
Sbjct: 2328 SMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTN-- 2385

Query: 3940 LPMKETGL--MYSIMVH-ALRAFRSDPGLLTNTMDVFVKEPSFDWK 3982
              M+ TGL   Y I  H  +   R     +   ++ FV +P  +W+
Sbjct: 2386 -AMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWR 2430


>gi|20336199 ataxia telangiectasia mutated isoform 2 [Homo sapiens]
          Length = 1708

 Score =  112 bits (279), Expect = 1e-23
 Identities = 105/413 (25%), Positives = 171/413 (41%), Gaps = 69/413 (16%)

Query: 3716 VRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILA 3775
            V I  F     +   +  PK I   G D +E   LVKG +DLRQD  ++Q+FQ+ N +L 
Sbjct: 1333 VTIQSFKAEFRLAGGVNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQ 1392

Query: 3776 QDSACSQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDVGAYMLMYK-GANRTE 3834
            +++   +R L + TY VVP++            +W T   G   +G +++  + GA++  
Sbjct: 1393 RNTETRKRKLTICTYKVVPLSQRSG------VLEWCT---GTVPIGEFLVNNEDGAHKRY 1443

Query: 3835 TVTSFRKRE-SKVPADLLKRAF----------------------VRMSTSPEAFLALRSH 3871
                F   +  K   ++ K++F                      +     P  +   R  
Sbjct: 1444 RPNDFSAFQCQKKMMEVQKKSFEEKYEVFMDVCQNFQPVFRYFCMEKFLDPAIWFEKRLA 1503

Query: 3872 FASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMPFRL 3931
            +  S A   I  +ILG+GDRH+ N ++  ++  ++ ID G AF    + LP PE +PFRL
Sbjct: 1504 YTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQG-KILPTPETVPFRL 1562

Query: 3932 TRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKMLKK 3991
            TR  ++ M      G+        +   R+    L   ++V + +P FDW     K L  
Sbjct: 1563 TRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQETLLTIVEVLLYDPLFDWTMNPLKAL-- 1620

Query: 3992 GGSWIQEINVAEKNWYPRQKI--CYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAVA 4049
               ++Q+    E   +P         KR L+  + +     E +L               
Sbjct: 1621 ---YLQQRPEDETELHPTLNADDQECKRNLSDIDQSFNKVAERVL--------------- 1662

Query: 4050 RGSKDHNIRAQEPESGLSEET------QVKCLMDQATDPNILGRTWEGWEPWM 4096
                   +R QE   G+ E T      QV  L+ QA DP  L R + GW+ W+
Sbjct: 1663 -------MRLQEKLKGVEEGTVLSVGGQVNLLIQQAIDPKNLSRLFPGWKAWV 1708


>gi|71902540 ataxia telangiectasia mutated isoform 1 [Homo sapiens]
          Length = 3056

 Score =  112 bits (279), Expect = 1e-23
 Identities = 105/413 (25%), Positives = 171/413 (41%), Gaps = 69/413 (16%)

Query: 3716 VRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILA 3775
            V I  F     +   +  PK I   G D +E   LVKG +DLRQD  ++Q+FQ+ N +L 
Sbjct: 2681 VTIQSFKAEFRLAGGVNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQ 2740

Query: 3776 QDSACSQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDVGAYMLMYK-GANRTE 3834
            +++   +R L + TY VVP++            +W T   G   +G +++  + GA++  
Sbjct: 2741 RNTETRKRKLTICTYKVVPLSQRSG------VLEWCT---GTVPIGEFLVNNEDGAHKRY 2791

Query: 3835 TVTSFRKRE-SKVPADLLKRAF----------------------VRMSTSPEAFLALRSH 3871
                F   +  K   ++ K++F                      +     P  +   R  
Sbjct: 2792 RPNDFSAFQCQKKMMEVQKKSFEEKYEVFMDVCQNFQPVFRYFCMEKFLDPAIWFEKRLA 2851

Query: 3872 FASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMPFRL 3931
            +  S A   I  +ILG+GDRH+ N ++  ++  ++ ID G AF    + LP PE +PFRL
Sbjct: 2852 YTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQG-KILPTPETVPFRL 2910

Query: 3932 TRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKMLKK 3991
            TR  ++ M      G+        +   R+    L   ++V + +P FDW     K L  
Sbjct: 2911 TRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQETLLTIVEVLLYDPLFDWTMNPLKAL-- 2968

Query: 3992 GGSWIQEINVAEKNWYPRQKI--CYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAVA 4049
               ++Q+    E   +P         KR L+  + +     E +L               
Sbjct: 2969 ---YLQQRPEDETELHPTLNADDQECKRNLSDIDQSFNKVAERVL--------------- 3010

Query: 4050 RGSKDHNIRAQEPESGLSEET------QVKCLMDQATDPNILGRTWEGWEPWM 4096
                   +R QE   G+ E T      QV  L+ QA DP  L R + GW+ W+
Sbjct: 3011 -------MRLQEKLKGVEEGTVLSVGGQVNLLIQQAIDPKNLSRLFPGWKAWV 3056


>gi|169218268 PREDICTED: similar to Serine-protein kinase ATM, partial
            [Homo sapiens]
          Length = 2934

 Score =  112 bits (279), Expect = 1e-23
 Identities = 105/413 (25%), Positives = 171/413 (41%), Gaps = 69/413 (16%)

Query: 3716 VRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILA 3775
            V I  F     +   +  PK I   G D +E   LVKG +DLRQD  ++Q+FQ+ N +L 
Sbjct: 2559 VTIQSFKAEFRLAGGVNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQ 2618

Query: 3776 QDSACSQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDVGAYMLMYK-GANRTE 3834
            +++   +R L + TY VVP++            +W T   G   +G +++  + GA++  
Sbjct: 2619 RNTETRKRKLTICTYKVVPLSQRSG------VLEWCT---GTVPIGEFLVNNEDGAHKRY 2669

Query: 3835 TVTSFRKRE-SKVPADLLKRAF----------------------VRMSTSPEAFLALRSH 3871
                F   +  K   ++ K++F                      +     P  +   R  
Sbjct: 2670 RPNDFSAFQCQKKMMEVQKKSFEEKYEVFMDVCQNFQPVFRYFCMEKFLDPAIWFEKRLA 2729

Query: 3872 FASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMPFRL 3931
            +  S A   I  +ILG+GDRH+ N ++  ++  ++ ID G AF    + LP PE +PFRL
Sbjct: 2730 YTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQG-KILPTPETVPFRL 2788

Query: 3932 TRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKMLKK 3991
            TR  ++ M      G+        +   R+    L   ++V + +P FDW     K L  
Sbjct: 2789 TRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQETLLTIVEVLLYDPLFDWTMNPLKAL-- 2846

Query: 3992 GGSWIQEINVAEKNWYPRQKI--CYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAVA 4049
               ++Q+    E   +P         KR L+  + +     E +L               
Sbjct: 2847 ---YLQQRPEDETELHPTLNADDQECKRNLSDIDQSFDKVAERVL--------------- 2888

Query: 4050 RGSKDHNIRAQEPESGLSEET------QVKCLMDQATDPNILGRTWEGWEPWM 4096
                   +R QE   G+ E T      QV  L+ QA DP  L R + GW+ W+
Sbjct: 2889 -------MRLQEKLKGVEEGTVLSVGGQVNLLIQQAIDPKNLSRLFPGWKAWV 2934


>gi|62243658 PI-3-kinase-related kinase SMG-1 [Homo sapiens]
          Length = 3661

 Score = 95.1 bits (235), Expect = 1e-18
 Identities = 88/378 (23%), Positives = 150/378 (39%), Gaps = 77/378 (20%)

Query: 3658 FNDITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVR 3717
            F +I   L  +  K +     L+E SPW++         E+ +PG+   R        V 
Sbjct: 2071 FKEIMLSLQQRAQKRASYILRLEEISPWLA----AMTNTEIALPGEVSARDT------VT 2120

Query: 3718 IAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQD 3777
            I      +T++ +  +PK+++  G D + +P+L KG EDL  D+R+ Q   ++N + A  
Sbjct: 2121 IHSVGGTITILPTKTKPKKLLFLGSDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFATI 2180

Query: 3778 SACSQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDVGAYMLMYKGANRTETVT 3837
            +         R YSV P+ +   R+   ++ D  T + G         +YK   + E   
Sbjct: 2181 NRQETPRFHARHYSVTPLGT---RSGLIQWVDGATPLFG---------LYKRWQQREAAL 2228

Query: 3838 SFRKRE--------------------SKV------------------PADLLKRAFVR-M 3858
              +K +                    SK+                  P  ++K      M
Sbjct: 2229 QAQKAQDSYQTPQNPGIVPRPSELYYSKIGPALKTVGLSLDVSRRDWPLHVMKAVLEELM 2288

Query: 3859 STSPEAFLA---------------LRSHFASSHALICISHWILGIGDRHLNNFMVAMETG 3903
              +P   LA               +   +A S A++ +  +I+G+GDRHL+N ++ M TG
Sbjct: 2289 EATPPNLLAKELWSSCTTPDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTG 2348

Query: 3904 GVIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDP 3963
             V+ ID+   F    + L VPE +PFR+T+     +      G+        L   R   
Sbjct: 2349 EVVHIDYNVCFEKG-KSLRVPEKVPFRMTQNIETALGVTGVEGVFRLSCEQVLHIMRRGR 2407

Query: 3964 GLLTNTMDVFVKEPSFDW 3981
              L   ++ FV +P  DW
Sbjct: 2408 ETLLTLLEAFVYDPLVDW 2425


>gi|34761064 catalytic phosphatidylinositol 3-kinase 3 [Homo sapiens]
          Length = 887

 Score = 68.2 bits (165), Expect = 2e-10
 Identities = 70/284 (24%), Positives = 119/284 (41%), Gaps = 41/284 (14%)

Query: 3644 GKGGSKLLRMKLSDFNDITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQ 3703
            G    +++R  L+      + L+  M    +  GN K+      + +++ L  + E    
Sbjct: 531  GDKSVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKK-----KNERLQALLGDNEKMNL 585

Query: 3704 YDGRGKPLP-EYHVRIAGF-DERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQ 3761
             D    PLP E  V+I G   E  T+  S   P ++  +  D  ++P + K G+DLRQDQ
Sbjct: 586  SDVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTEDGGKYPVIFKHGDDLRQDQ 645

Query: 3762 RVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDVG 3821
             + Q+  +M+ +L +++      L+L  Y V+                     S KH   
Sbjct: 646  LILQIISLMDKLLRKENL----DLKLTPYKVL-------------------ATSTKHGFM 682

Query: 3822 AYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLA-LRSHFASSHALIC 3880
             ++     A   +T  S +            R +      P    A +   +  S A  C
Sbjct: 683  QFIQSVPVAEVLDTEGSIQN---------FFRKYAPSENGPNGISAEVMDTYVKSCAGYC 733

Query: 3881 ISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVP 3924
            +  +ILG+GDRHL+N ++  +TG +  IDFG+  G   + LP P
Sbjct: 734  VITYILGVGDRHLDNLLLT-KTGKLFHIDFGYILGRDPKPLPPP 776


>gi|4507691 transformation/transcription domain-associated protein
            [Homo sapiens]
          Length = 3830

 Score = 67.8 bits (164), Expect = 2e-10
 Identities = 119/583 (20%), Positives = 220/583 (37%), Gaps = 105/583 (18%)

Query: 3489 VPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPF--------IISSESYS 3540
            VP  Q+++WI  ++  L   +   + + + ++   YPQA+ +P         I   E Y 
Sbjct: 3197 VPPIQWLAWIPQLLTCLVGSEGKLLLNLISQVGRVYPQAVYFPIRTLYLTLKIEQRERYK 3256

Query: 3541 ------------FKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWS 3588
                        ++ +   H  +E    + S L+  G++   +             ++W 
Sbjct: 3257 SDPGPIRATAPMWRCSRIMHMQRELHPTLLSSLE--GIVDQMV----------WFRENWH 3304

Query: 3589 NDVRAELAKTPVNKKNIEKMYERMY---AALGDPK-APGLGAFRRKFIQTFGKEFDK--- 3641
             +V  +L      ++ + K Y   +    A+ D K  P    F +K + TFG   +    
Sbjct: 3305 EEVLRQL------QQGLAKCYSVAFEKSGAVSDAKITPHTLNFVKKLVSTFGVGLENVSN 3358

Query: 3642 ---HFGKGGSKLLRMKLSDFNDITNMLLLK----MNKDSKPPGNLK------ECSPWMS- 3687
                F    S+ L  +            LK     + D   PG++K      +   W+  
Sbjct: 3359 VSTMFSSAASESLARRAQATAQDPVFQKLKGQFTTDFDFSVPGSMKLHNLISKLKKWIKI 3418

Query: 3688 --------------DFKVEFLRN------ELEIPGQYDGRGKPLP-EYHVRIAGFDERVT 3726
                          + K  FL N      E+EIPG++     P P  Y+++IA F  RV 
Sbjct: 3419 LEAKTKQLPKFFLIEEKCRFLSNFSAQTAEVEIPGEFL---MPKPTHYYIKIARFMPRVE 3475

Query: 3727 VMASLRRP-KRIIIRGHDEREHPFLVKGGEDL---RQDQRVEQLFQVMNGILAQDSACSQ 3782
            ++       +R+ IRGH+ + +P+LV     L   R+++RV QL +++N  L +    ++
Sbjct: 3476 IVQKHNTAARRLYIRGHNGKIYPYLVMNDACLTESRREERVLQLLRLLNPCLEKRKETTK 3535

Query: 3783 RALQL---RTYSVVP---MTSSDPRAPPCE--YKDWLTKMSGKHD--VGAYM-----LMY 3827
            R L     R  +V P   +   +P +      YK    K   +HD  +  Y      +  
Sbjct: 3536 RHLFFTVPRVVAVSPQMRLVEDNPSSLSLVEIYKQRCAKKGIEHDNPISRYYDRLATVQA 3595

Query: 3828 KGANRTETVTSFRKRE---SKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHW 3884
            +G   +  V     +E   + VP  +LK   +    +   +   R  F    ALI  + +
Sbjct: 3596 RGTQASHQVLRDILKEVQSNMVPRSMLKEWALHTFPNATDYWTFRKMFTIQLALIGFAEF 3655

Query: 3885 ILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKE 3944
            +L +   +     +A +TG +    F      AT  L     +PFRLT      +  +  
Sbjct: 3656 VLHLNRLNPEMLQIAQDTGKLNVAYFRFDINDATGDLDANRPVPFRLTPNISEFLTTIGV 3715

Query: 3945 TGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQK 3987
            +G + + M+   R F      +   +   +++    W    Q+
Sbjct: 3716 SGPLTASMIAVARCFAQPNFKVDGILKTVLRDEIIAWHKKTQE 3758


>gi|21237725 phosphoinositide-3-kinase, catalytic, gamma polypeptide
            [Homo sapiens]
          Length = 1102

 Score = 66.6 bits (161), Expect = 5e-10
 Identities = 60/223 (26%), Positives = 92/223 (41%), Gaps = 32/223 (14%)

Query: 3723 ERVTVMASLRRPKRIIIRGHD-----EREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQD 3777
            E+  VMAS ++P  +  +  D           + K G+DLRQD  + Q+ ++M  I   +
Sbjct: 799  EKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETE 858

Query: 3778 SACSQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDVGAYMLMYKGANRTETVT 3837
            S      L L  Y  +                     S    +G   ++       +   
Sbjct: 859  SL----DLCLLPYGCI---------------------STGDKIGMIEIVKDATTIAKIQQ 893

Query: 3838 SFRKRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFM 3897
            S          ++L       S + E F A    F  S A  C++ ++LGIGDRH +N M
Sbjct: 894  STVGNTGAFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIM 953

Query: 3898 VAMETGGVIGIDFGHAFGSATQFLPV-PELMPFRLTRQFINLM 3939
            +  ETG +  IDFGH  G+   FL +  E +PF LT  F+ +M
Sbjct: 954  IT-ETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVM 995


>gi|156564405 catalytic phosphatidylinositol 3-kinase delta [Homo
            sapiens]
          Length = 1044

 Score = 61.2 bits (147), Expect = 2e-08
 Identities = 60/222 (27%), Positives = 95/222 (42%), Gaps = 31/222 (13%)

Query: 3723 ERVTVMASLRRPKRIIIRGHDEREHP---FLVKGGEDLRQDQRVEQLFQVMNGILAQDSA 3779
            E+ T M S  +P  I+    +         + K G+DLRQD    Q+ Q+M+ +  Q+  
Sbjct: 747  EQCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGL 806

Query: 3780 CSQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMS-GKHDVGAYMLMYKGANRTETVTS 3838
                 L++  Y  +P              D +  +   K ++ A     K A        
Sbjct: 807  ----DLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDA-------L 855

Query: 3839 FRKRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFMV 3898
                +SK P + L RA                 F  S A  C++ ++LGIGDRH +N M+
Sbjct: 856  LNWLKSKNPGEALDRAI--------------EEFTLSCAGYCVATYVLGIGDRHSDNIMI 901

Query: 3899 AMETGGVIGIDFGHAFGS-ATQFLPVPELMPFRLTRQFINLM 3939
              E+G +  IDFGH  G+  T+F    E +PF LT  F++++
Sbjct: 902  -RESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVI 942


>gi|5453894 catalytic phosphatidylinositol 3-kinase beta [Homo
            sapiens]
          Length = 1070

 Score = 56.2 bits (134), Expect = 6e-07
 Identities = 55/197 (27%), Positives = 86/197 (43%), Gaps = 38/197 (19%)

Query: 3750 LVKGGEDLRQDQRVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSSDPRAPPCEYKD 3809
            + K G+DLRQD    Q+ ++M      D    +  L LR      + + D          
Sbjct: 803  IFKNGDDLRQDMLTLQMLRLM------DLLWKEAGLDLRMLPYGCLATGD---------- 846

Query: 3810 WLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPA------DLLKRAFVRMSTSPE 3863
                 SG  +V          + +ET+   +   S V A      D L       ++  +
Sbjct: 847  ----RSGLIEV---------VSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDD 893

Query: 3864 AFLALRSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGS-ATQFLP 3922
               A+   F  S A  C++ ++LGIGDRH +N MV  +TG +  IDFGH  G+  ++F  
Sbjct: 894  LDRAIEE-FTLSCAGYCVASYVLGIGDRHSDNIMV-KKTGQLFHIDFGHILGNFKSKFGI 951

Query: 3923 VPELMPFRLTRQFINLM 3939
              E +PF LT  FI+++
Sbjct: 952  KRERVPFILTYDFIHVI 968


>gi|169218238 PREDICTED: similar to ataxia telangiectasia and Rad3
            related protein, partial [Homo sapiens]
          Length = 2105

 Score = 51.6 bits (122), Expect = 2e-05
 Identities = 23/63 (36%), Positives = 42/63 (66%)

Query: 3709 KPLPEYHVRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQ 3768
            +P P +   IAGFD+ V ++ASL++PK+I ++G D + +  + K  +DLR+D R+ +   
Sbjct: 2042 EPFPGHWAYIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNS 2101

Query: 3769 VMN 3771
            ++N
Sbjct: 2102 LIN 2104


>gi|4505809 catalytic phosphatidylinositol 4-kinase beta [Homo
            sapiens]
          Length = 828

 Score = 47.8 bits (112), Expect = 2e-04
 Identities = 29/81 (35%), Positives = 47/81 (58%), Gaps = 2/81 (2%)

Query: 3859 STSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSAT 3918
            S + EAFL+ + +F  S A  C+  ++L + DRH  N ++  E G +I IDFG    S+ 
Sbjct: 652  SYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAE-GHIIHIDFGFILSSSP 710

Query: 3919 QFLPVPELMPFRLTRQFINLM 3939
            + L   E   F+LT +F+++M
Sbjct: 711  RNLGF-ETSAFKLTTEFVDVM 730


>gi|54792082 phosphoinositide-3-kinase, catalytic, alpha polypeptide
            [Homo sapiens]
          Length = 1068

 Score = 45.8 bits (107), Expect = 9e-04
 Identities = 57/221 (25%), Positives = 90/221 (40%), Gaps = 33/221 (14%)

Query: 3723 ERVTVMASLRRPKRIIIRGHDE------REHPFLVKGGEDLRQDQRVEQLFQVMNGILAQ 3776
            E   +M+S +RP  +     D       + +  + K G+DLRQD    Q+ ++M  I   
Sbjct: 767  EECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIW-- 824

Query: 3777 DSACSQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDVGAYMLMYKGANRTETV 3836
                  + L LR      ++  D        ++  T M  +   G      KGA +  + 
Sbjct: 825  ----QNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGL-----KGALQFNSH 875

Query: 3837 TSFRKRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLNNF 3896
            T  +  + K   ++   A                 F  S A  C++ +ILGIGDRH +N 
Sbjct: 876  TLHQWLKDKNKGEIYDAAI--------------DLFTRSCAGYCVATFILGIGDRHNSNI 921

Query: 3897 MVAMETGGVIGIDFGHAFG-SATQFLPVPELMPFRLTRQFI 3936
            MV  + G +  IDFGH       +F    E +PF LT+ F+
Sbjct: 922  MV-KDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFL 961


>gi|194353959 phosphoinositide-3-kinase, class 2 gamma polypeptide
            [Homo sapiens]
          Length = 1445

 Score = 45.8 bits (107), Expect = 9e-04
 Identities = 49/171 (28%), Positives = 71/171 (41%), Gaps = 27/171 (15%)

Query: 3750 LVKGGEDLRQDQRVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSSDPRAPPCEYKD 3809
            + K G+DLRQD  V QL QVM+ I  Q+    Q  +  R  S           P      
Sbjct: 919  IFKAGDDLRQDMLVLQLIQVMDNIWLQEGLDMQMIIY-RCLSTGKDQGLVQMVPDAVTLA 977

Query: 3810 WLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLALR 3869
             + + SG            G  +  T+  +  + + + AD  K              ALR
Sbjct: 978  KIHRHSG----------LIGPLKENTIKKWFSQHNHLKADYEK--------------ALR 1013

Query: 3870 SHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQF 3920
            + F S  A  C+  +ILG+ DRH +N M+  ++G +  IDFG   G A  F
Sbjct: 1014 NFFYSC-AGWCVVTFILGVCDRHNDNIMLT-KSGHMFHIDFGKFLGHAQTF 1062


>gi|194097347 phosphoinositide-3-kinase, class 2 beta polypeptide
            [Homo sapiens]
          Length = 1634

 Score = 44.7 bits (104), Expect = 0.002
 Identities = 47/171 (27%), Positives = 72/171 (42%), Gaps = 27/171 (15%)

Query: 3750 LVKGGEDLRQDQRVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSSDPRAPPCEYKD 3809
            + K G+DLRQD    Q+ ++M+ I  Q+     R +  R +S           P  E   
Sbjct: 1081 IFKCGDDLRQDMLTLQMIRIMSKIWVQEGL-DMRMVIFRCFSTGRGRGMVEMIPNAET-- 1137

Query: 3810 WLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLALR 3869
             L K+  +H V                 SF+ R     AD L++     +   + +    
Sbjct: 1138 -LRKIQVEHGVTG---------------SFKDRPL---ADWLQKH----NPGEDEYEKAV 1174

Query: 3870 SHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQF 3920
             +F  S A  C++ ++LGI DRH +N M+   TG +  IDFG   G A  F
Sbjct: 1175 ENFIYSCAGCCVATYVLGICDRHNDNIML-KTTGHMFHIDFGRFLGHAQMF 1224


>gi|157671929 phosphoinositide-3-kinase, class 2 alpha polypeptide
            [Homo sapiens]
          Length = 1686

 Score = 43.9 bits (102), Expect = 0.003
 Identities = 56/232 (24%), Positives = 94/232 (40%), Gaps = 36/232 (15%)

Query: 3750 LVKGGEDLRQDQRVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSSDPRAPP--CEY 3807
            + K GEDLRQD    Q+ ++M+ I  ++       L LR      +++   R        
Sbjct: 1136 MFKVGEDLRQDMLALQMIKIMDKIWLKEG------LDLRMVIFKCLSTGRDRGMVELVPA 1189

Query: 3808 KDWLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLA 3867
             D L K+  ++ V                 SF+    K  A+ L++     + S E +  
Sbjct: 1190 SDTLRKIQVEYGVTG---------------SFK---DKPLAEWLRK----YNPSEEEYEK 1227

Query: 3868 LRSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVP-EL 3926
               +F  S A  C++ ++LGI DRH +N M+   TG +  IDFG   G A  F     + 
Sbjct: 1228 ASENFIYSCAGCCVATYVLGICDRHNDNIML-RSTGHMFHIDFGKFLGHAQMFGSFKRDR 1286

Query: 3927 MPFRLTRQFINLMLPMKETGLMYSIMV----HALRAFRSDPGLLTNTMDVFV 3974
             PF LT     ++   ++  + + + V     A    R    L  N + + +
Sbjct: 1287 APFVLTSDMAYVINGGEKPTIRFQLFVDLCCQAYNLIRKQTNLFLNLLSLMI 1338


>gi|148886661 exportin 4 [Homo sapiens]
          Length = 1151

 Score = 36.2 bits (82), Expect = 0.69
 Identities = 44/179 (24%), Positives = 78/179 (43%), Gaps = 25/179 (13%)

Query: 169  TVLEKVYELLGLLGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLS 228
            T+  + Y+L+  + E+ P ++    E+LF++ +  L+  MTS   E    V   CL+ L+
Sbjct: 975  TLCNQYYKLITFICEIFPEKIPQLPEDLFKSLMYSLELGMTSMSSE----VCQLCLEALT 1030

Query: 229  SLLCNFTKSMEEDPQTSREIFNFVLKAIRPQIDLKRY------AVPSAGLRLFALHASQF 282
             L     K+ E D        +F LK +   + L+++      A   A   L  LH +++
Sbjct: 1031 PLAEQCAKAQETDSPLFLATRHF-LKLVFDMLVLQKHNTEMTTAAGEAFYTLVCLHQAEY 1089

Query: 283  S---TCLLDN------YVSLFEVLLKWCAHT-----NVELKKAALSALESFLKQVSNMV 327
            S     LL +      Y  L +   K  A +     + + K A L +LE F+  V  ++
Sbjct: 1090 SELVETLLSSQQDPVIYQRLADAFNKLTASSTPPTLDRKQKMAFLKSLEEFMANVGGLL 1148


>gi|223941912 coiled-coil domain containing 135 [Homo sapiens]
          Length = 874

 Score = 35.8 bits (81), Expect = 0.90
 Identities = 23/58 (39%), Positives = 31/58 (53%), Gaps = 10/58 (17%)

Query: 2546 SPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHPLSECEFQEYTIDSDWRFRSTVLTP 2603
            +PK E H L +A NF  + + + PD   P+F HPL+ECE          +F ST L P
Sbjct: 88   TPK-EEHLLQVADNFSRQYSHLCPDRV-PLFLHPLNECEVP--------KFVSTTLRP 135


>gi|188497683 FAST kinase domains 1 [Homo sapiens]
          Length = 847

 Score = 35.0 bits (79), Expect = 1.5
 Identities = 31/143 (21%), Positives = 67/143 (46%), Gaps = 26/143 (18%)

Query: 280 SQFSTCLLDNYVSLFEVLLKWC--AHTNVELKKAALSALESFLKQVSNMVAKNAEMHK-N 336
           S+FS+CL D ++    ++ K     H N+E  +  LS+L   +  +S++++++ +    N
Sbjct: 156 SEFSSCLADQHLYFSPLMGKIADIVHRNLETTQD-LSSLSVLMVNISSLISRHFQQQLVN 214

Query: 337 KLQYFMEQFYGIIRNVDSNNKELSIAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMF 396
           K +   +        +DS+   ++ +I  +            ++V + Y  L++RC  +F
Sbjct: 215 KTELLFD-------TIDSSEVNVAKSIAKF-----------LRNVRYRYQPLLERCNNVF 256

Query: 397 LTQTDTGDY----RVYQMPSFLQ 415
           L+  D  D     ++  +  FLQ
Sbjct: 257 LSNVDHLDLDSISKILSVYKFLQ 279


>gi|4505807 phosphatidylinositol 4-kinase type 3 alpha isoform 1 [Homo
            sapiens]
          Length = 854

 Score = 34.3 bits (77), Expect = 2.6
 Identities = 43/168 (25%), Positives = 60/168 (35%), Gaps = 32/168 (19%)

Query: 3750 LVKGGEDLRQDQRVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSSDPRAPPCEYKD 3809
            + K G+D RQD    Q+  +   I  Q           R  +  P        P C  +D
Sbjct: 600  IFKVGDDCRQDMLALQIIDLFKNIF-QLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRD 658

Query: 3810 WLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLALR 3869
             L + +   D G Y                         D   R +   ST   AF   R
Sbjct: 659  QLGRQT---DFGMY-------------------------DYFTRQYGDESTL--AFQQAR 688

Query: 3870 SHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSA 3917
             +F  S A   +  ++L I DRH  N M+  + G +I IDFG  F S+
Sbjct: 689  YNFIRSMAAYSLLLFLLQIKDRHNGNIMLD-KKGHIIHIDFGFMFESS 735


>gi|155030226 phosphatidylinositol 4-kinase type 3 alpha isoform 2
            [Homo sapiens]
          Length = 2044

 Score = 34.3 bits (77), Expect = 2.6
 Identities = 43/168 (25%), Positives = 60/168 (35%), Gaps = 32/168 (19%)

Query: 3750 LVKGGEDLRQDQRVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSSDPRAPPCEYKD 3809
            + K G+D RQD    Q+  +   I  Q           R  +  P        P C  +D
Sbjct: 1790 IFKVGDDCRQDMLALQIIDLFKNIF-QLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRD 1848

Query: 3810 WLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLALR 3869
             L + +   D G Y                         D   R +   ST   AF   R
Sbjct: 1849 QLGRQT---DFGMY-------------------------DYFTRQYGDESTL--AFQQAR 1878

Query: 3870 SHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSA 3917
             +F  S A   +  ++L I DRH  N M+  + G +I IDFG  F S+
Sbjct: 1879 YNFIRSMAAYSLLLFLLQIKDRHNGNIMLD-KKGHIIHIDFGFMFESS 1925


>gi|41352697 centromere protein I [Homo sapiens]
          Length = 756

 Score = 34.3 bits (77), Expect = 2.6
 Identities = 22/72 (30%), Positives = 39/72 (54%), Gaps = 8/72 (11%)

Query: 822 AQKGFNKVVLKHLKKTKNLSSNEAISLEEIRIRV-VQMLGSLGGQINKNLL------TVT 874
           A +  +K + KHLK  +N++    ++ EEI I + + + G  G  +N  +L      TV 
Sbjct: 80  ASQNKDKTLEKHLKTVENVAWKNGLASEEIDILLNIALSGKFGNAVNTRILKCMIPATVI 139

Query: 875 SSDEMMKSYVAW 886
           S D ++K+ V+W
Sbjct: 140 SEDSVVKA-VSW 150


>gi|239757646 PREDICTED: similar to phosphatidylinositol 4-kinase type
            3 alpha [Homo sapiens]
          Length = 286

 Score = 33.9 bits (76), Expect = 3.4
 Identities = 43/168 (25%), Positives = 60/168 (35%), Gaps = 32/168 (19%)

Query: 3750 LVKGGEDLRQDQRVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSSDPRAPPCEYKD 3809
            + K G+D RQD    Q+  +   I  Q           R  +  P        P C  +D
Sbjct: 54   IFKLGDDCRQDMLALQIIDLFKNIF-QLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRD 112

Query: 3810 WLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLALR 3869
             L + +   D G Y                         D   R +   ST   AF   R
Sbjct: 113  QLGRQT---DFGMY-------------------------DYFTRQYGDESTL--AFQQAR 142

Query: 3870 SHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSA 3917
             +F  S A   +  ++L I DRH  N M+  + G +I IDFG  F S+
Sbjct: 143  YNFIRSMAAYSLLLFLLQIKDRHNGNIMLD-KKGHIIHIDFGFMFESS 189


>gi|122937502 transmembrane channel-like 3 [Homo sapiens]
          Length = 1100

 Score = 33.9 bits (76), Expect = 3.4
 Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 11/95 (11%)

Query: 2093 CMAPLTALVKHMHRSL--GPPQGEE-------DSVPRDLPSWMKFLHGKLGNPIVPLNIR 2143
            CM P    +     SL  GP  G+E       +++ +D P W   + G + +P+V L   
Sbjct: 631  CMLPTIFAIVRYKPSLNCGPFSGQEKIYDIVSETIEKDFPVWFGSVVGHISSPVVILPAV 690

Query: 2144 LFLAKLVINTEEVFR--PYAKHWLSPLLQLAASEN 2176
            L L  L+   + + R    + H L   +Q A SE+
Sbjct: 691  LLLFMLIYYLQSIARSLKLSNHQLKMQIQNARSED 725


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 33.1 bits (74), Expect = 5.8
 Identities = 62/277 (22%), Positives = 112/277 (40%), Gaps = 36/277 (12%)

Query: 3218 EVQEQEEDISSLIRSCKFSMKMKMIDSARKQNNFSLAMKLL----KELHKESKTRDDWLV 3273
            E QE+EE+    +     +++ ++ D+ +K ++    ++ L    K+L K+++     L 
Sbjct: 1350 EQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLE 1409

Query: 3274 SWVQSYCRLSHCRSRSQGCSEQVLTVLKTVSLLDENNVSSYLNKNILAFRDQNILLGTTY 3333
                +Y +L   ++R Q    Q L  L TV L  +  V+S L K    F DQ  LL    
Sbjct: 1410 EKALAYDKLEKTKNRLQ----QELDDL-TVDLDHQRQVASNLEKKQKKF-DQ--LLAEEK 1461

Query: 3334 RIIANALSSEPACLAEIEEDKARRILELSGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEE 3393
             I A          AE  E K  + L L+ +  E  E       +  F+  ++ ++A  E
Sbjct: 1462 SISARYAEERDRAEAEARE-KETKALSLARALEEALEA------KEEFERQNKQLRADME 1514

Query: 3394 EAQPPSWSCGPAAGVID----AYMTLADFCDQQLRKEEENASVTDSAELQAYPALVVEKM 3449
            +        G     ++    A     +    QL + E+    T+ A+L+          
Sbjct: 1515 DLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLR---------- 1564

Query: 3450 LKALKLNSNEARLKFPRLLQIIERYPEETLSLMTKEI 3486
               L++N    + +F R LQ  +   EE   L+ K++
Sbjct: 1565 ---LEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQV 1598


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 150,174,383
Number of Sequences: 37866
Number of extensions: 6678364
Number of successful extensions: 16441
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 16240
Number of HSP's gapped (non-prelim): 168
length of query: 4096
length of database: 18,247,518
effective HSP length: 123
effective length of query: 3973
effective length of database: 13,590,000
effective search space: 53993070000
effective search space used: 53993070000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 72 (32.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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