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Search of human proteins with 113430845
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|113430845 PREDICTED: similar to protein kinase,
DNA-activated, catalytic polypeptide [Homo sapiens]
(4096 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|113430845 PREDICTED: similar to protein kinase, DNA-activated... 8161 0.0
gi|126032350 protein kinase, DNA-activated, catalytic polypeptid... 8147 0.0
gi|13654237 protein kinase, DNA-activated, catalytic polypeptide... 8131 0.0
gi|157266317 ataxia telangiectasia and Rad3 related protein [Hom... 142 9e-33
gi|169165926 PREDICTED: similar to ataxia telangiectasia and Rad... 142 9e-33
gi|4826730 FK506 binding protein 12-rapamycin associated protein... 140 3e-32
gi|20336199 ataxia telangiectasia mutated isoform 2 [Homo sapiens] 112 1e-23
gi|71902540 ataxia telangiectasia mutated isoform 1 [Homo sapiens] 112 1e-23
gi|169218268 PREDICTED: similar to Serine-protein kinase ATM, pa... 112 1e-23
gi|62243658 PI-3-kinase-related kinase SMG-1 [Homo sapiens] 95 1e-18
gi|34761064 catalytic phosphatidylinositol 3-kinase 3 [Homo sapi... 68 2e-10
gi|4507691 transformation/transcription domain-associated protei... 68 2e-10
gi|21237725 phosphoinositide-3-kinase, catalytic, gamma polypept... 67 5e-10
gi|156564405 catalytic phosphatidylinositol 3-kinase delta [Homo... 61 2e-08
gi|5453894 catalytic phosphatidylinositol 3-kinase beta [Homo sa... 56 6e-07
gi|169218238 PREDICTED: similar to ataxia telangiectasia and Rad... 52 2e-05
gi|4505809 catalytic phosphatidylinositol 4-kinase beta [Homo sa... 48 2e-04
gi|54792082 phosphoinositide-3-kinase, catalytic, alpha polypept... 46 9e-04
gi|194353959 phosphoinositide-3-kinase, class 2 gamma polypeptid... 46 9e-04
gi|194097347 phosphoinositide-3-kinase, class 2 beta polypeptide... 45 0.002
gi|157671929 phosphoinositide-3-kinase, class 2 alpha polypeptid... 44 0.003
gi|148886661 exportin 4 [Homo sapiens] 36 0.69
gi|223941912 coiled-coil domain containing 135 [Homo sapiens] 36 0.90
gi|188497683 FAST kinase domains 1 [Homo sapiens] 35 1.5
gi|4505807 phosphatidylinositol 4-kinase type 3 alpha isoform 1 ... 34 2.6
gi|155030226 phosphatidylinositol 4-kinase type 3 alpha isoform ... 34 2.6
gi|41352697 centromere protein I [Homo sapiens] 34 2.6
gi|239757646 PREDICTED: similar to phosphatidylinositol 4-kinase... 34 3.4
gi|122937502 transmembrane channel-like 3 [Homo sapiens] 34 3.4
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 33 5.8
>gi|113430845 PREDICTED: similar to protein kinase, DNA-activated,
catalytic polypeptide [Homo sapiens]
Length = 4096
Score = 8161 bits (21175), Expect = 0.0
Identities = 4096/4096 (100%), Positives = 4096/4096 (100%)
Query: 1 MAGSGAGVRCSLLRLQETLSAADRCGAALAGHQLIRGLGQECVLSSSPAVLALQTSLVFS 60
MAGSGAGVRCSLLRLQETLSAADRCGAALAGHQLIRGLGQECVLSSSPAVLALQTSLVFS
Sbjct: 1 MAGSGAGVRCSLLRLQETLSAADRCGAALAGHQLIRGLGQECVLSSSPAVLALQTSLVFS 60
Query: 61 RDFGLLVFVRKSLNSIEFRECREEILKFLCIFLEKMGQKIAPYSVEIKNTCTSVYTKDRA 120
RDFGLLVFVRKSLNSIEFRECREEILKFLCIFLEKMGQKIAPYSVEIKNTCTSVYTKDRA
Sbjct: 61 RDFGLLVFVRKSLNSIEFRECREEILKFLCIFLEKMGQKIAPYSVEIKNTCTSVYTKDRA 120
Query: 121 AKCKIPALDLLIKLLQTFRSSRLMDEFKIGELFSKFYGELALKKKIPDTVLEKVYELLGL 180
AKCKIPALDLLIKLLQTFRSSRLMDEFKIGELFSKFYGELALKKKIPDTVLEKVYELLGL
Sbjct: 121 AKCKIPALDLLIKLLQTFRSSRLMDEFKIGELFSKFYGELALKKKIPDTVLEKVYELLGL 180
Query: 181 LGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE 240
LGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE
Sbjct: 181 LGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE 240
Query: 241 DPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKW 300
DPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKW
Sbjct: 241 DPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKW 300
Query: 301 CAHTNVELKKAALSALESFLKQVSNMVAKNAEMHKNKLQYFMEQFYGIIRNVDSNNKELS 360
CAHTNVELKKAALSALESFLKQVSNMVAKNAEMHKNKLQYFMEQFYGIIRNVDSNNKELS
Sbjct: 301 CAHTNVELKKAALSALESFLKQVSNMVAKNAEMHKNKLQYFMEQFYGIIRNVDSNNKELS 360
Query: 361 IAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTQTDTGDYRVYQMPSFLQSVASV 420
IAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTQTDTGDYRVYQMPSFLQSVASV
Sbjct: 361 IAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTQTDTGDYRVYQMPSFLQSVASV 420
Query: 421 LLYLDTVPEVYTPVLEHLVVMQIDSFPQYSPKMQLVCCRAIVKVFLALAAKGPVLRNCIS 480
LLYLDTVPEVYTPVLEHLVVMQIDSFPQYSPKMQLVCCRAIVKVFLALAAKGPVLRNCIS
Sbjct: 421 LLYLDTVPEVYTPVLEHLVVMQIDSFPQYSPKMQLVCCRAIVKVFLALAAKGPVLRNCIS 480
Query: 481 TVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQM 540
TVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQM
Sbjct: 481 TVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQM 540
Query: 541 MDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGV 600
MDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGV
Sbjct: 541 MDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGV 600
Query: 601 WMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRL 660
WMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRL
Sbjct: 601 WMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRL 660
Query: 661 PLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAVKMKQ 720
PLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAVKMKQ
Sbjct: 661 PLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAVKMKQ 720
Query: 721 YKDELLASCLTFLLSLPHNIIELDVRAYVPALQMAFKLGLSYTPLAEVGLNALEEWSIYI 780
YKDELLASCLTFLLSLPHNIIELDVRAYVPALQMAFKLGLSYTPLAEVGLNALEEWSIYI
Sbjct: 721 YKDELLASCLTFLLSLPHNIIELDVRAYVPALQMAFKLGLSYTPLAEVGLNALEEWSIYI 780
Query: 781 DRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSRAAQKGFNKVVLKHLKKTKNL 840
DRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSRAAQKGFNKVVLKHLKKTKNL
Sbjct: 781 DRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSRAAQKGFNKVVLKHLKKTKNL 840
Query: 841 SSNEAISLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDREKRLSFAVPFRE 900
SSNEAISLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDREKRLSFAVPFRE
Sbjct: 841 SSNEAISLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDREKRLSFAVPFRE 900
Query: 901 MKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGKATQMPEGGQGAPPMYQ 960
MKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGKATQMPEGGQGAPPMYQ
Sbjct: 901 MKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGKATQMPEGGQGAPPMYQ 960
Query: 961 LYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVSLLEAILDGIVDP 1020
LYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVSLLEAILDGIVDP
Sbjct: 961 LYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVSLLEAILDGIVDP 1020
Query: 1021 VDSTLRDFCGRCIREFLKWSIKQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASL 1080
VDSTLRDFCGRCIREFLKWSIKQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASL
Sbjct: 1021 VDSTLRDFCGRCIREFLKWSIKQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASL 1080
Query: 1081 AFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEK 1140
AFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEK
Sbjct: 1081 AFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEK 1140
Query: 1141 KHVSLNKAKKRRLPRGFPPSASLCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPG 1200
KHVSLNKAKKRRLPRGFPPSASLCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPG
Sbjct: 1141 KHVSLNKAKKRRLPRGFPPSASLCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPG 1200
Query: 1201 NRSPNLWLKDVLKEEGVSFLINTFEGGGCGQPSGILAQPTLLYLRGPFSLQATLCWLDLL 1260
NRSPNLWLKDVLKEEGVSFLINTFEGGGCGQPSGILAQPTLLYLRGPFSLQATLCWLDLL
Sbjct: 1201 NRSPNLWLKDVLKEEGVSFLINTFEGGGCGQPSGILAQPTLLYLRGPFSLQATLCWLDLL 1260
Query: 1261 LAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFLESIAMHDIIAAEKCFGTGAAGN 1320
LAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFLESIAMHDIIAAEKCFGTGAAGN
Sbjct: 1261 LAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFLESIAMHDIIAAEKCFGTGAAGN 1320
Query: 1321 RTSPQEGERYNYSKCTVVVRIMEFTTTLLNTSPEGWKLLKKDLCNTHLMRVLVQTLCEPA 1380
RTSPQEGERYNYSKCTVVVRIMEFTTTLLNTSPEGWKLLKKDLCNTHLMRVLVQTLCEPA
Sbjct: 1321 RTSPQEGERYNYSKCTVVVRIMEFTTTLLNTSPEGWKLLKKDLCNTHLMRVLVQTLCEPA 1380
Query: 1381 SIGFNIGDVQVMAHLPDVCVNLMKALKMSPYKDILETHLREKITAQSIEELCAVNLYGPD 1440
SIGFNIGDVQVMAHLPDVCVNLMKALKMSPYKDILETHLREKITAQSIEELCAVNLYGPD
Sbjct: 1381 SIGFNIGDVQVMAHLPDVCVNLMKALKMSPYKDILETHLREKITAQSIEELCAVNLYGPD 1440
Query: 1441 AQVDRSRLAAVVSACKQLHRAGLLHNILPSQSTDLHHSVGTELLSLVYKGIAPGDERQCL 1500
AQVDRSRLAAVVSACKQLHRAGLLHNILPSQSTDLHHSVGTELLSLVYKGIAPGDERQCL
Sbjct: 1441 AQVDRSRLAAVVSACKQLHRAGLLHNILPSQSTDLHHSVGTELLSLVYKGIAPGDERQCL 1500
Query: 1501 PSLDLSCKQLASGLLELAFAFGGLCERLVSLLLNPAVLSTASLGSSQGSVIHFSHGEYFY 1560
PSLDLSCKQLASGLLELAFAFGGLCERLVSLLLNPAVLSTASLGSSQGSVIHFSHGEYFY
Sbjct: 1501 PSLDLSCKQLASGLLELAFAFGGLCERLVSLLLNPAVLSTASLGSSQGSVIHFSHGEYFY 1560
Query: 1561 SLFSETINTELLKNLDLAVLELMQSSVDNTKMVSAVLNGMLDQSFRERANQKHQGLKLAT 1620
SLFSETINTELLKNLDLAVLELMQSSVDNTKMVSAVLNGMLDQSFRERANQKHQGLKLAT
Sbjct: 1561 SLFSETINTELLKNLDLAVLELMQSSVDNTKMVSAVLNGMLDQSFRERANQKHQGLKLAT 1620
Query: 1621 TILQHWKKCDSWWAKDSPLETKMAVLALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLA 1680
TILQHWKKCDSWWAKDSPLETKMAVLALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLA
Sbjct: 1621 TILQHWKKCDSWWAKDSPLETKMAVLALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLA 1680
Query: 1681 DTKLDLHLKGQAVTLLPFFTSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYV 1740
DTKLDLHLKGQAVTLLPFFTSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYV
Sbjct: 1681 DTKLDLHLKGQAVTLLPFFTSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYV 1740
Query: 1741 DCMKKFLDALELSQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLES 1800
DCMKKFLDALELSQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLES
Sbjct: 1741 DCMKKFLDALELSQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLES 1800
Query: 1801 VYEMFRKDDPRLSFTRQSFVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLKSRFTKLNE 1860
VYEMFRKDDPRLSFTRQSFVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLKSRFTKLNE
Sbjct: 1801 VYEMFRKDDPRLSFTRQSFVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLKSRFTKLNE 1860
Query: 1861 STFDTQITKKMGYYKILDVMYSRLPKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCY 1920
STFDTQITKKMGYYKILDVMYSRLPKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCY
Sbjct: 1861 STFDTQITKKMGYYKILDVMYSRLPKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCY 1920
Query: 1921 DAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLLIFEN 1980
DAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLLIFEN
Sbjct: 1921 DAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLLIFEN 1980
Query: 1981 LIDLKRRYNFPVEVEVPMERKKKYIEIRKEAREAANGDSDGPSYMSSLSYLADSTLSEEM 2040
LIDLKRRYNFPVEVEVPMERKKKYIEIRKEAREAANGDSDGPSYMSSLSYLADSTLSEEM
Sbjct: 1981 LIDLKRRYNFPVEVEVPMERKKKYIEIRKEAREAANGDSDGPSYMSSLSYLADSTLSEEM 2040
Query: 2041 SQFDFSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTAL 2100
SQFDFSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTAL
Sbjct: 2041 SQFDFSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTAL 2100
Query: 2101 VKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPY 2160
VKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPY
Sbjct: 2101 VKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPY 2160
Query: 2161 AKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGLATPTGVPKDEVLANRLLNFLM 2220
AKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGLATPTGVPKDEVLANRLLNFLM
Sbjct: 2161 AKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGLATPTGVPKDEVLANRLLNFLM 2220
Query: 2221 KHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIV 2280
KHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIV
Sbjct: 2221 KHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIV 2280
Query: 2281 MANDLPPYDPQCGIQSSEYFQALVNNMSFVRYKEVYAAAAEVLGLILRYVMERKNILEES 2340
MANDLPPYDPQCGIQSSEYFQALVNNMSFVRYKEVYAAAAEVLGLILRYVMERKNILEES
Sbjct: 2281 MANDLPPYDPQCGIQSSEYFQALVNNMSFVRYKEVYAAAAEVLGLILRYVMERKNILEES 2340
Query: 2341 LCELVAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEV 2400
LCELVAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEV
Sbjct: 2341 LCELVAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEV 2400
Query: 2401 VLCRVEGMTELYFQLKSKDFVQVMRHRDERQKVCLDIIYKMMPKLKPVELRELLNPVVEF 2460
VLCRVEGMTELYFQLKSKDFVQVMRHRDERQKVCLDIIYKMMPKLKPVELRELLNPVVEF
Sbjct: 2401 VLCRVEGMTELYFQLKSKDFVQVMRHRDERQKVCLDIIYKMMPKLKPVELRELLNPVVEF 2460
Query: 2461 VSHPSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLII 2520
VSHPSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLII
Sbjct: 2461 VSHPSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLII 2520
Query: 2521 RNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHPL 2580
RNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHPL
Sbjct: 2521 RNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHPL 2580
Query: 2581 SECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQQ 2640
SECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQQ
Sbjct: 2581 SECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQQ 2640
Query: 2641 HDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSDSLLFAHKRSERLQRAPLKSVGPDFG 2700
HDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSDSLLFAHKRSERLQRAPLKSVGPDFG
Sbjct: 2641 HDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSDSLLFAHKRSERLQRAPLKSVGPDFG 2700
Query: 2701 KKRLGLPGDEVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSEL 2760
KKRLGLPGDEVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSEL
Sbjct: 2701 KKRLGLPGDEVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSEL 2760
Query: 2761 KMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEMD 2820
KMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEMD
Sbjct: 2761 KMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEMD 2820
Query: 2821 KFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAVSAGCL 2880
KFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAVSAGCL
Sbjct: 2821 KFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAVSAGCL 2880
Query: 2881 ASLQQPVGIRLLEEALLRLLPAELPAKRVRGKARLPPDVLRWVELAKLYRSIGEYDVLRG 2940
ASLQQPVGIRLLEEALLRLLPAELPAKRVRGKARLPPDVLRWVELAKLYRSIGEYDVLRG
Sbjct: 2881 ASLQQPVGIRLLEEALLRLLPAELPAKRVRGKARLPPDVLRWVELAKLYRSIGEYDVLRG 2940
Query: 2941 IFTSEIGTKQITQSALLAEARSDYSEAAKQYDEALNKQDWVDGEPTEAEKDFWELASLDC 3000
IFTSEIGTKQITQSALLAEARSDYSEAAKQYDEALNKQDWVDGEPTEAEKDFWELASLDC
Sbjct: 2941 IFTSEIGTKQITQSALLAEARSDYSEAAKQYDEALNKQDWVDGEPTEAEKDFWELASLDC 3000
Query: 3001 YNHLAEWKSLEYCSTASIDSENPPDLNKIWSEPFYQETYLPYMIRSKLKLLLQGEADQSL 3060
YNHLAEWKSLEYCSTASIDSENPPDLNKIWSEPFYQETYLPYMIRSKLKLLLQGEADQSL
Sbjct: 3001 YNHLAEWKSLEYCSTASIDSENPPDLNKIWSEPFYQETYLPYMIRSKLKLLLQGEADQSL 3060
Query: 3061 LTFIDKAMHGELQKAILELHYSQELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVLL 3120
LTFIDKAMHGELQKAILELHYSQELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVLL
Sbjct: 3061 LTFIDKAMHGELQKAILELHYSQELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVLL 3120
Query: 3121 HQSRLTKLQSVQALTEIQEFISFISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWDD 3180
HQSRLTKLQSVQALTEIQEFISFISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWDD
Sbjct: 3121 HQSRLTKLQSVQALTEIQEFISFISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWDD 3180
Query: 3181 IITNRCFFLSKIEEKLTPLPEDNSMNVDQDGDPSDRMEVQEQEEDISSLIRSCKFSMKMK 3240
IITNRCFFLSKIEEKLTPLPEDNSMNVDQDGDPSDRMEVQEQEEDISSLIRSCKFSMKMK
Sbjct: 3181 IITNRCFFLSKIEEKLTPLPEDNSMNVDQDGDPSDRMEVQEQEEDISSLIRSCKFSMKMK 3240
Query: 3241 MIDSARKQNNFSLAMKLLKELHKESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTVL 3300
MIDSARKQNNFSLAMKLLKELHKESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTVL
Sbjct: 3241 MIDSARKQNNFSLAMKLLKELHKESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTVL 3300
Query: 3301 KTVSLLDENNVSSYLNKNILAFRDQNILLGTTYRIIANALSSEPACLAEIEEDKARRILE 3360
KTVSLLDENNVSSYLNKNILAFRDQNILLGTTYRIIANALSSEPACLAEIEEDKARRILE
Sbjct: 3301 KTVSLLDENNVSSYLNKNILAFRDQNILLGTTYRIIANALSSEPACLAEIEEDKARRILE 3360
Query: 3361 LSGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFCD 3420
LSGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFCD
Sbjct: 3361 LSGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFCD 3420
Query: 3421 QQLRKEEENASVTDSAELQAYPALVVEKMLKALKLNSNEARLKFPRLLQIIERYPEETLS 3480
QQLRKEEENASVTDSAELQAYPALVVEKMLKALKLNSNEARLKFPRLLQIIERYPEETLS
Sbjct: 3421 QQLRKEEENASVTDSAELQAYPALVVEKMLKALKLNSNEARLKFPRLLQIIERYPEETLS 3480
Query: 3481 LMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESYS 3540
LMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESYS
Sbjct: 3481 LMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESYS 3540
Query: 3541 FKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTPV 3600
FKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTPV
Sbjct: 3541 FKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTPV 3600
Query: 3601 NKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFND 3660
NKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFND
Sbjct: 3601 NKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFND 3660
Query: 3661 ITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVRIAG 3720
ITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVRIAG
Sbjct: 3661 ITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVRIAG 3720
Query: 3721 FDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSAC 3780
FDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSAC
Sbjct: 3721 FDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSAC 3780
Query: 3781 SQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDVGAYMLMYKGANRTETVTSFR 3840
SQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDVGAYMLMYKGANRTETVTSFR
Sbjct: 3781 SQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDVGAYMLMYKGANRTETVTSFR 3840
Query: 3841 KRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFMVAM 3900
KRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFMVAM
Sbjct: 3841 KRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFMVAM 3900
Query: 3901 ETGGVIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKETGLMYSIMVHALRAFR 3960
ETGGVIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKETGLMYSIMVHALRAFR
Sbjct: 3901 ETGGVIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKETGLMYSIMVHALRAFR 3960
Query: 3961 SDPGLLTNTMDVFVKEPSFDWKNFEQKMLKKGGSWIQEINVAEKNWYPRQKICYAKRKLA 4020
SDPGLLTNTMDVFVKEPSFDWKNFEQKMLKKGGSWIQEINVAEKNWYPRQKICYAKRKLA
Sbjct: 3961 SDPGLLTNTMDVFVKEPSFDWKNFEQKMLKKGGSWIQEINVAEKNWYPRQKICYAKRKLA 4020
Query: 4021 GANPAVITCDELLLGHEKAPAFRDYVAVARGSKDHNIRAQEPESGLSEETQVKCLMDQAT 4080
GANPAVITCDELLLGHEKAPAFRDYVAVARGSKDHNIRAQEPESGLSEETQVKCLMDQAT
Sbjct: 4021 GANPAVITCDELLLGHEKAPAFRDYVAVARGSKDHNIRAQEPESGLSEETQVKCLMDQAT 4080
Query: 4081 DPNILGRTWEGWEPWM 4096
DPNILGRTWEGWEPWM
Sbjct: 4081 DPNILGRTWEGWEPWM 4096
>gi|126032350 protein kinase, DNA-activated, catalytic polypeptide
isoform 2 [Homo sapiens]
Length = 4097
Score = 8147 bits (21139), Expect = 0.0
Identities = 4092/4097 (99%), Positives = 4094/4097 (99%), Gaps = 1/4097 (0%)
Query: 1 MAGSGAGVRCSLLRLQETLSAADRCGAALAGHQLIRGLGQECVLSSSPAVLALQTSLVFS 60
MAGSGAGVRCSLLRLQETLSAADRCGAALAGHQLIRGLGQECVLSSSPAVLALQTSLVFS
Sbjct: 1 MAGSGAGVRCSLLRLQETLSAADRCGAALAGHQLIRGLGQECVLSSSPAVLALQTSLVFS 60
Query: 61 RDFGLLVFVRKSLNSIEFRECREEILKFLCIFLEKMGQKIAPYSVEIKNTCTSVYTKDRA 120
RDFGLLVFVRKSLNSIEFRECREEILKFLCIFLEKMGQKIAPYSVEIKNTCTSVYTKDRA
Sbjct: 61 RDFGLLVFVRKSLNSIEFRECREEILKFLCIFLEKMGQKIAPYSVEIKNTCTSVYTKDRA 120
Query: 121 AKCKIPALDLLIKLLQTFRSSRLMDEFKIGELFSKFYGELALKKKIPDTVLEKVYELLGL 180
AKCKIPALDLLIKLLQTFRSSRLMDEFKIGELFSKFYGELALKKKIPDTVLEKVYELLGL
Sbjct: 121 AKCKIPALDLLIKLLQTFRSSRLMDEFKIGELFSKFYGELALKKKIPDTVLEKVYELLGL 180
Query: 181 LGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE 240
LGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE
Sbjct: 181 LGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE 240
Query: 241 DPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKW 300
DPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKW
Sbjct: 241 DPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKW 300
Query: 301 CAHTNVELKKAALSALESFLKQVSNMVAKNAEMHKNKLQYFMEQFYGIIRNVDSNNKELS 360
CAHTNVELKKAALSALESFLKQVSNMVAKNAEMHKNKLQYFMEQFYGIIRNVDSNNKELS
Sbjct: 301 CAHTNVELKKAALSALESFLKQVSNMVAKNAEMHKNKLQYFMEQFYGIIRNVDSNNKELS 360
Query: 361 IAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTQTDTGDYRVYQMPSFLQSVASV 420
IAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTQTDTGD RVYQMPSFLQSVASV
Sbjct: 361 IAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTQTDTGDDRVYQMPSFLQSVASV 420
Query: 421 LLYLDTVPEVYTPVLEHLVVMQIDSFPQYSPKMQLVCCRAIVKVFLALAAKGPVLRNCIS 480
LLYLDTVPEVYTPVLEHLVVMQIDSFPQYSPKMQLVCCRAIVKVFLALAAKGPVLRNCIS
Sbjct: 421 LLYLDTVPEVYTPVLEHLVVMQIDSFPQYSPKMQLVCCRAIVKVFLALAAKGPVLRNCIS 480
Query: 481 TVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQM 540
TVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQM
Sbjct: 481 TVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQM 540
Query: 541 MDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGV 600
MDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGV
Sbjct: 541 MDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGV 600
Query: 601 WMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRL 660
WMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRL
Sbjct: 601 WMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRL 660
Query: 661 PLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAVKMKQ 720
PLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAVKMKQ
Sbjct: 661 PLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAVKMKQ 720
Query: 721 YKDELLASCLTFLLSLPHNIIELDVRAYVPALQMAFKLGLSYTPLAEVGLNALEEWSIYI 780
YKDELLASCLTFLLSLPHNIIELDVRAYVPALQMAFKLGLSYTPLAEVGLNALEEWSIYI
Sbjct: 721 YKDELLASCLTFLLSLPHNIIELDVRAYVPALQMAFKLGLSYTPLAEVGLNALEEWSIYI 780
Query: 781 DRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSRAAQKGFNKVVLKHLKKTKNL 840
DRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSRAAQKGFNKVVLKHLKKTKNL
Sbjct: 781 DRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSRAAQKGFNKVVLKHLKKTKNL 840
Query: 841 SSNEAISLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDREKRLSFAVPFRE 900
SSNEAISLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDREKRLSFAVPFRE
Sbjct: 841 SSNEAISLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDREKRLSFAVPFRE 900
Query: 901 MKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGKATQMPEGGQGAPPMYQ 960
MKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGKATQMPEGGQGAPPMYQ
Sbjct: 901 MKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGKATQMPEGGQGAPPMYQ 960
Query: 961 LYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVSLLEAILDGIVDP 1020
LYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTV+LLEAILDGIVDP
Sbjct: 961 LYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVALLEAILDGIVDP 1020
Query: 1021 VDSTLRDFCGRCIREFLKWSIKQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASL 1080
VDSTLRDFCGRCIREFLKWSIKQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASL
Sbjct: 1021 VDSTLRDFCGRCIREFLKWSIKQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASL 1080
Query: 1081 AFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEK 1140
AFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEK
Sbjct: 1081 AFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEK 1140
Query: 1141 KHVSLNKAKKRRLPRGFPPSASLCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPG 1200
KHVSLNKAKKRRLPRGFPPSASLCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPG
Sbjct: 1141 KHVSLNKAKKRRLPRGFPPSASLCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPG 1200
Query: 1201 NRSPNLWLKDVLKEEGVSFLINTFEGGGCGQPSGILAQPTLLYLRGPFSLQATLCWLDLL 1260
NRSPNLWLKDVLKEEGVSFLINTFEGGGCGQPSGILAQPTLLYLRGPFSLQATLCWLDLL
Sbjct: 1201 NRSPNLWLKDVLKEEGVSFLINTFEGGGCGQPSGILAQPTLLYLRGPFSLQATLCWLDLL 1260
Query: 1261 LAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFLESIAMHDIIAAEKCFGTGAAGN 1320
LAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFLESIAMHDIIAAEKCFGTGAAGN
Sbjct: 1261 LAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFLESIAMHDIIAAEKCFGTGAAGN 1320
Query: 1321 RTSPQEGERYNYSKCTVVVRIMEFTTTLLNTSPEGWKLLKKDLCNTHLMRVLVQTLCEPA 1380
RTSPQEGERYNYSKCTVVVRIMEFTTTLLNTSPEGWKLLKKDLCNTHLMRVLVQTLCEPA
Sbjct: 1321 RTSPQEGERYNYSKCTVVVRIMEFTTTLLNTSPEGWKLLKKDLCNTHLMRVLVQTLCEPA 1380
Query: 1381 SIGFNIGDVQVMAHLPDVCVNLMKALKMSPYKDILETHLREKITAQSIEELCAVNLYGPD 1440
SIGFNIGDVQVMAHLPDVCVNLMKALKMSPYKDILETHLREKITAQSIEELCAVNLYGPD
Sbjct: 1381 SIGFNIGDVQVMAHLPDVCVNLMKALKMSPYKDILETHLREKITAQSIEELCAVNLYGPD 1440
Query: 1441 AQVDRSRLAAVVSACKQLHRAGLLHNILPSQSTDLHHSVGTELLSLVYKGIAPGDERQCL 1500
AQVDRSRLAAVVSACKQLHRAGLLHNILPSQSTDLHHSVGTELLSLVYKGIAPGDERQCL
Sbjct: 1441 AQVDRSRLAAVVSACKQLHRAGLLHNILPSQSTDLHHSVGTELLSLVYKGIAPGDERQCL 1500
Query: 1501 PSLDLSCKQLASGLLELAFAFGGLCERLVSLLLNPAVLSTASLGSSQGSVIHFSHGEYFY 1560
PSLDLSCKQLASGLLELAFAFGGLCERLVSLLLNPAVLSTASLGSSQGSVIHFSHGEYFY
Sbjct: 1501 PSLDLSCKQLASGLLELAFAFGGLCERLVSLLLNPAVLSTASLGSSQGSVIHFSHGEYFY 1560
Query: 1561 SLFSETINTELLKNLDLAVLELMQSSVDNTKMVSAVLNGMLDQSFRERANQKHQGLKLAT 1620
SLFSETINTELLKNLDLAVLELMQSSVDNTKMVSAVLNGMLDQSFRERANQKHQGLKLAT
Sbjct: 1561 SLFSETINTELLKNLDLAVLELMQSSVDNTKMVSAVLNGMLDQSFRERANQKHQGLKLAT 1620
Query: 1621 TILQHWKKCDSWWAKDSPLETKMAVLALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLA 1680
TILQHWKKCDSWWAKDSPLETKMAVLALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLA
Sbjct: 1621 TILQHWKKCDSWWAKDSPLETKMAVLALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLA 1680
Query: 1681 DTKLDLHLKGQAVTLLPFFTSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYV 1740
DTKLDLHLKGQAVTLLPFFTSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYV
Sbjct: 1681 DTKLDLHLKGQAVTLLPFFTSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYV 1740
Query: 1741 DCMKKFLDALELSQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLES 1800
DCMKKFLDALELSQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLES
Sbjct: 1741 DCMKKFLDALELSQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLES 1800
Query: 1801 VYEMFRKDDPRLSFTRQSFVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLKSRFTKLNE 1860
VYEMFRKDDPRLSFTRQSFVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLKSRFTKLNE
Sbjct: 1801 VYEMFRKDDPRLSFTRQSFVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLKSRFTKLNE 1860
Query: 1861 STFDTQITKKMGYYKILDVMYSRLPKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCY 1920
STFDTQITKKMGYYKILDVMYSRLPKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCY
Sbjct: 1861 STFDTQITKKMGYYKILDVMYSRLPKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCY 1920
Query: 1921 DAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLLIFEN 1980
DAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLLIFEN
Sbjct: 1921 DAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLLIFEN 1980
Query: 1981 LIDLKRRYNFPVEVEVPMERKKKYIEIRKEAREAANGDSDGPSYMSSLSYLADSTLSEEM 2040
LIDLKRRYNFPVEVEVPMERKKKYIEIRKEAREAANGDSDGPSYMSSLSYLADSTLSEEM
Sbjct: 1981 LIDLKRRYNFPVEVEVPMERKKKYIEIRKEAREAANGDSDGPSYMSSLSYLADSTLSEEM 2040
Query: 2041 SQFDFSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTAL 2100
SQFDFSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTAL
Sbjct: 2041 SQFDFSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTAL 2100
Query: 2101 VKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPY 2160
VKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPY
Sbjct: 2101 VKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPY 2160
Query: 2161 AKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGLATPTGVPKDEVLANRLLNFLM 2220
AKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGLATPTGVPKDEVLANRLLNFLM
Sbjct: 2161 AKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGLATPTGVPKDEVLANRLLNFLM 2220
Query: 2221 KHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIV 2280
KHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIV
Sbjct: 2221 KHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIV 2280
Query: 2281 MANDLPPYDPQCGIQSSEYFQALVNNMSFVRYKEVYAAAAEVLGLILRYVMERKNILEES 2340
MANDLPPYDPQCGIQSSEYFQALVNNMSFVRYKEVYAAAAEVLGLILRYVMERKNILEES
Sbjct: 2281 MANDLPPYDPQCGIQSSEYFQALVNNMSFVRYKEVYAAAAEVLGLILRYVMERKNILEES 2340
Query: 2341 LCELVAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEV 2400
LCELVAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEV
Sbjct: 2341 LCELVAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEV 2400
Query: 2401 VLCRVEGMTELYFQLKSKDFVQVMRHR-DERQKVCLDIIYKMMPKLKPVELRELLNPVVE 2459
VLCRVEGMTELYFQLKSKDFVQVMRHR DERQKVCLDIIYKMMPKLKPVELRELLNPVVE
Sbjct: 2401 VLCRVEGMTELYFQLKSKDFVQVMRHRDDERQKVCLDIIYKMMPKLKPVELRELLNPVVE 2460
Query: 2460 FVSHPSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLI 2519
FVSHPSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLI
Sbjct: 2461 FVSHPSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLI 2520
Query: 2520 IRNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHP 2579
IRNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHP
Sbjct: 2521 IRNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHP 2580
Query: 2580 LSECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQ 2639
LSECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQ
Sbjct: 2581 LSECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQ 2640
Query: 2640 QHDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSDSLLFAHKRSERLQRAPLKSVGPDF 2699
QHDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSDSLLFAHKRSERLQRAPLKSVGPDF
Sbjct: 2641 QHDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSDSLLFAHKRSERLQRAPLKSVGPDF 2700
Query: 2700 GKKRLGLPGDEVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSE 2759
GKKRLGLPGDEVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSE
Sbjct: 2701 GKKRLGLPGDEVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSE 2760
Query: 2760 LKMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEM 2819
LKMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEM
Sbjct: 2761 LKMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEM 2820
Query: 2820 DKFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAVSAGC 2879
DKFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAVSAGC
Sbjct: 2821 DKFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAVSAGC 2880
Query: 2880 LASLQQPVGIRLLEEALLRLLPAELPAKRVRGKARLPPDVLRWVELAKLYRSIGEYDVLR 2939
LASLQQPVGIRLLEEALLRLLPAELPAKRVRGKARLPPDVLRWVELAKLYRSIGEYDVLR
Sbjct: 2881 LASLQQPVGIRLLEEALLRLLPAELPAKRVRGKARLPPDVLRWVELAKLYRSIGEYDVLR 2940
Query: 2940 GIFTSEIGTKQITQSALLAEARSDYSEAAKQYDEALNKQDWVDGEPTEAEKDFWELASLD 2999
GIFTSEIGTKQITQSALLAEARSDYSEAAKQYDEALNKQDWVDGEPTEAEKDFWELASLD
Sbjct: 2941 GIFTSEIGTKQITQSALLAEARSDYSEAAKQYDEALNKQDWVDGEPTEAEKDFWELASLD 3000
Query: 3000 CYNHLAEWKSLEYCSTASIDSENPPDLNKIWSEPFYQETYLPYMIRSKLKLLLQGEADQS 3059
CYNHLAEWKSLEYCSTASIDSENPPDLNKIWSEPFYQETYLPYMIRSKLKLLLQGEADQS
Sbjct: 3001 CYNHLAEWKSLEYCSTASIDSENPPDLNKIWSEPFYQETYLPYMIRSKLKLLLQGEADQS 3060
Query: 3060 LLTFIDKAMHGELQKAILELHYSQELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVL 3119
LLTFIDKAMHGELQKAILELHYSQELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVL
Sbjct: 3061 LLTFIDKAMHGELQKAILELHYSQELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVL 3120
Query: 3120 LHQSRLTKLQSVQALTEIQEFISFISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWD 3179
LHQSRLTKLQSVQALTEIQEFISFISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWD
Sbjct: 3121 LHQSRLTKLQSVQALTEIQEFISFISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWD 3180
Query: 3180 DIITNRCFFLSKIEEKLTPLPEDNSMNVDQDGDPSDRMEVQEQEEDISSLIRSCKFSMKM 3239
DIITNRCFFLSKIEEKLTPLPEDNSMNVDQDGDPSDRMEVQEQEEDISSLIRSCKFSMKM
Sbjct: 3181 DIITNRCFFLSKIEEKLTPLPEDNSMNVDQDGDPSDRMEVQEQEEDISSLIRSCKFSMKM 3240
Query: 3240 KMIDSARKQNNFSLAMKLLKELHKESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTV 3299
KMIDSARKQNNFSLAMKLLKELHKESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTV
Sbjct: 3241 KMIDSARKQNNFSLAMKLLKELHKESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTV 3300
Query: 3300 LKTVSLLDENNVSSYLNKNILAFRDQNILLGTTYRIIANALSSEPACLAEIEEDKARRIL 3359
LKTVSLLDENNVSSYL+KNILAFRDQNILLGTTYRIIANALSSEPACLAEIEEDKARRIL
Sbjct: 3301 LKTVSLLDENNVSSYLSKNILAFRDQNILLGTTYRIIANALSSEPACLAEIEEDKARRIL 3360
Query: 3360 ELSGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFC 3419
ELSGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFC
Sbjct: 3361 ELSGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFC 3420
Query: 3420 DQQLRKEEENASVTDSAELQAYPALVVEKMLKALKLNSNEARLKFPRLLQIIERYPEETL 3479
DQQLRKEEENASV DSAELQAYPALVVEKMLKALKLNSNEARLKFPRLLQIIERYPEETL
Sbjct: 3421 DQQLRKEEENASVIDSAELQAYPALVVEKMLKALKLNSNEARLKFPRLLQIIERYPEETL 3480
Query: 3480 SLMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESY 3539
SLMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESY
Sbjct: 3481 SLMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESY 3540
Query: 3540 SFKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTP 3599
SFKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTP
Sbjct: 3541 SFKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTP 3600
Query: 3600 VNKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFN 3659
VNKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFN
Sbjct: 3601 VNKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFN 3660
Query: 3660 DITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVRIA 3719
DITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVRIA
Sbjct: 3661 DITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVRIA 3720
Query: 3720 GFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSA 3779
GFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSA
Sbjct: 3721 GFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSA 3780
Query: 3780 CSQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDVGAYMLMYKGANRTETVTSF 3839
CSQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDVGAYMLMYKGANRTETVTSF
Sbjct: 3781 CSQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDVGAYMLMYKGANRTETVTSF 3840
Query: 3840 RKRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFMVA 3899
RKRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFMVA
Sbjct: 3841 RKRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFMVA 3900
Query: 3900 METGGVIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKETGLMYSIMVHALRAF 3959
METGGVIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKETGLMYSIMVHALRAF
Sbjct: 3901 METGGVIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKETGLMYSIMVHALRAF 3960
Query: 3960 RSDPGLLTNTMDVFVKEPSFDWKNFEQKMLKKGGSWIQEINVAEKNWYPRQKICYAKRKL 4019
RSDPGLLTNTMDVFVKEPSFDWKNFEQKMLKKGGSWIQEINVAEKNWYPRQKICYAKRKL
Sbjct: 3961 RSDPGLLTNTMDVFVKEPSFDWKNFEQKMLKKGGSWIQEINVAEKNWYPRQKICYAKRKL 4020
Query: 4020 AGANPAVITCDELLLGHEKAPAFRDYVAVARGSKDHNIRAQEPESGLSEETQVKCLMDQA 4079
AGANPAVITCDELLLGHEKAPAFRDYVAVARGSKDHNIRAQEPESGLSEETQVKCLMDQA
Sbjct: 4021 AGANPAVITCDELLLGHEKAPAFRDYVAVARGSKDHNIRAQEPESGLSEETQVKCLMDQA 4080
Query: 4080 TDPNILGRTWEGWEPWM 4096
TDPNILGRTWEGWEPWM
Sbjct: 4081 TDPNILGRTWEGWEPWM 4097
>gi|13654237 protein kinase, DNA-activated, catalytic polypeptide
isoform 1 [Homo sapiens]
Length = 4128
Score = 8131 bits (21097), Expect = 0.0
Identities = 4092/4128 (99%), Positives = 4094/4128 (99%), Gaps = 32/4128 (0%)
Query: 1 MAGSGAGVRCSLLRLQETLSAADRCGAALAGHQLIRGLGQECVLSSSPAVLALQTSLVFS 60
MAGSGAGVRCSLLRLQETLSAADRCGAALAGHQLIRGLGQECVLSSSPAVLALQTSLVFS
Sbjct: 1 MAGSGAGVRCSLLRLQETLSAADRCGAALAGHQLIRGLGQECVLSSSPAVLALQTSLVFS 60
Query: 61 RDFGLLVFVRKSLNSIEFRECREEILKFLCIFLEKMGQKIAPYSVEIKNTCTSVYTKDRA 120
RDFGLLVFVRKSLNSIEFRECREEILKFLCIFLEKMGQKIAPYSVEIKNTCTSVYTKDRA
Sbjct: 61 RDFGLLVFVRKSLNSIEFRECREEILKFLCIFLEKMGQKIAPYSVEIKNTCTSVYTKDRA 120
Query: 121 AKCKIPALDLLIKLLQTFRSSRLMDEFKIGELFSKFYGELALKKKIPDTVLEKVYELLGL 180
AKCKIPALDLLIKLLQTFRSSRLMDEFKIGELFSKFYGELALKKKIPDTVLEKVYELLGL
Sbjct: 121 AKCKIPALDLLIKLLQTFRSSRLMDEFKIGELFSKFYGELALKKKIPDTVLEKVYELLGL 180
Query: 181 LGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE 240
LGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE
Sbjct: 181 LGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE 240
Query: 241 DPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKW 300
DPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKW
Sbjct: 241 DPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKW 300
Query: 301 CAHTNVELKKAALSALESFLKQVSNMVAKNAEMHKNKLQYFMEQFYGIIRNVDSNNKELS 360
CAHTNVELKKAALSALESFLKQVSNMVAKNAEMHKNKLQYFMEQFYGIIRNVDSNNKELS
Sbjct: 301 CAHTNVELKKAALSALESFLKQVSNMVAKNAEMHKNKLQYFMEQFYGIIRNVDSNNKELS 360
Query: 361 IAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTQTDTGDYRVYQMPSFLQSVASV 420
IAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTQTDTGD RVYQMPSFLQSVASV
Sbjct: 361 IAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTQTDTGDDRVYQMPSFLQSVASV 420
Query: 421 LLYLDTVPEVYTPVLEHLVVMQIDSFPQYSPKMQLVCCRAIVKVFLALAAKGPVLRNCIS 480
LLYLDTVPEVYTPVLEHLVVMQIDSFPQYSPKMQLVCCRAIVKVFLALAAKGPVLRNCIS
Sbjct: 421 LLYLDTVPEVYTPVLEHLVVMQIDSFPQYSPKMQLVCCRAIVKVFLALAAKGPVLRNCIS 480
Query: 481 TVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQM 540
TVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQM
Sbjct: 481 TVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQM 540
Query: 541 MDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGV 600
MDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGV
Sbjct: 541 MDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGV 600
Query: 601 WMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRL 660
WMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRL
Sbjct: 601 WMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRL 660
Query: 661 PLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAVKMKQ 720
PLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAVKMKQ
Sbjct: 661 PLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAVKMKQ 720
Query: 721 YKDELLASCLTFLLSLPHNIIELDVRAYVPALQMAFKLGLSYTPLAEVGLNALEEWSIYI 780
YKDELLASCLTFLLSLPHNIIELDVRAYVPALQMAFKLGLSYTPLAEVGLNALEEWSIYI
Sbjct: 721 YKDELLASCLTFLLSLPHNIIELDVRAYVPALQMAFKLGLSYTPLAEVGLNALEEWSIYI 780
Query: 781 DRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSRAAQKGFNKVVLKHLKKTKNL 840
DRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSRAAQKGFNKVVLKHLKKTKNL
Sbjct: 781 DRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSRAAQKGFNKVVLKHLKKTKNL 840
Query: 841 SSNEAISLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDREKRLSFAVPFRE 900
SSNEAISLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDREKRLSFAVPFRE
Sbjct: 841 SSNEAISLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDREKRLSFAVPFRE 900
Query: 901 MKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGKATQMPEGGQGAPPMYQ 960
MKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGKATQMPEGGQGAPPMYQ
Sbjct: 901 MKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGKATQMPEGGQGAPPMYQ 960
Query: 961 LYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVSLLEAILDGIVDP 1020
LYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTV+LLEAILDGIVDP
Sbjct: 961 LYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVALLEAILDGIVDP 1020
Query: 1021 VDSTLRDFCGRCIREFLKWSIKQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASL 1080
VDSTLRDFCGRCIREFLKWSIKQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASL
Sbjct: 1021 VDSTLRDFCGRCIREFLKWSIKQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASL 1080
Query: 1081 AFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEK 1140
AFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEK
Sbjct: 1081 AFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEK 1140
Query: 1141 KHVSLNKAKKRRLPRGFPPSASLCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPG 1200
KHVSLNKAKKRRLPRGFPPSASLCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPG
Sbjct: 1141 KHVSLNKAKKRRLPRGFPPSASLCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPG 1200
Query: 1201 NRSPNLWLKDVLKEEGVSFLINTFEGGGCGQPSGILAQPTLLYLRGPFSLQATLCWLDLL 1260
NRSPNLWLKDVLKEEGVSFLINTFEGGGCGQPSGILAQPTLLYLRGPFSLQATLCWLDLL
Sbjct: 1201 NRSPNLWLKDVLKEEGVSFLINTFEGGGCGQPSGILAQPTLLYLRGPFSLQATLCWLDLL 1260
Query: 1261 LAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFLESIAMHDIIAAEKCFGTGAAGN 1320
LAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFLESIAMHDIIAAEKCFGTGAAGN
Sbjct: 1261 LAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFLESIAMHDIIAAEKCFGTGAAGN 1320
Query: 1321 RTSPQEGERYNYSKCTVVVRIMEFTTTLLNTSPEGWKLLKKDLCNTHLMRVLVQTLCEPA 1380
RTSPQEGERYNYSKCTVVVRIMEFTTTLLNTSPEGWKLLKKDLCNTHLMRVLVQTLCEPA
Sbjct: 1321 RTSPQEGERYNYSKCTVVVRIMEFTTTLLNTSPEGWKLLKKDLCNTHLMRVLVQTLCEPA 1380
Query: 1381 SIGFNIGDVQVMAHLPDVCVNLMKALKMSPYKDILETHLREKITAQSIEELCAVNLYGPD 1440
SIGFNIGDVQVMAHLPDVCVNLMKALKMSPYKDILETHLREKITAQSIEELCAVNLYGPD
Sbjct: 1381 SIGFNIGDVQVMAHLPDVCVNLMKALKMSPYKDILETHLREKITAQSIEELCAVNLYGPD 1440
Query: 1441 AQVDRSRLAAVVSACKQLHRAGLLHNILPSQSTDLHHSVGTELLSLVYKGIAPGDERQCL 1500
AQVDRSRLAAVVSACKQLHRAGLLHNILPSQSTDLHHSVGTELLSLVYKGIAPGDERQCL
Sbjct: 1441 AQVDRSRLAAVVSACKQLHRAGLLHNILPSQSTDLHHSVGTELLSLVYKGIAPGDERQCL 1500
Query: 1501 PSLDLSCKQLASGLLELAFAFGGLCERLVSLLLNPAVLSTASLGSSQGSVIHFSHGEYFY 1560
PSLDLSCKQLASGLLELAFAFGGLCERLVSLLLNPAVLSTASLGSSQGSVIHFSHGEYFY
Sbjct: 1501 PSLDLSCKQLASGLLELAFAFGGLCERLVSLLLNPAVLSTASLGSSQGSVIHFSHGEYFY 1560
Query: 1561 SLFSETINTELLKNLDLAVLELMQSSVDNTKMVSAVLNGMLDQSFRERANQKHQGLKLAT 1620
SLFSETINTELLKNLDLAVLELMQSSVDNTKMVSAVLNGMLDQSFRERANQKHQGLKLAT
Sbjct: 1561 SLFSETINTELLKNLDLAVLELMQSSVDNTKMVSAVLNGMLDQSFRERANQKHQGLKLAT 1620
Query: 1621 TILQHWKKCDSWWAKDSPLETKMAVLALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLA 1680
TILQHWKKCDSWWAKDSPLETKMAVLALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLA
Sbjct: 1621 TILQHWKKCDSWWAKDSPLETKMAVLALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLA 1680
Query: 1681 DTKLDLHLKGQAVTLLPFFTSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYV 1740
DTKLDLHLKGQAVTLLPFFTSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYV
Sbjct: 1681 DTKLDLHLKGQAVTLLPFFTSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYV 1740
Query: 1741 DCMKKFLDALELSQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLES 1800
DCMKKFLDALELSQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLES
Sbjct: 1741 DCMKKFLDALELSQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLES 1800
Query: 1801 VYEMFRKDDPRLSFTRQSFVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLKSRFTKLNE 1860
VYEMFRKDDPRLSFTRQSFVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLKSRFTKLNE
Sbjct: 1801 VYEMFRKDDPRLSFTRQSFVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLKSRFTKLNE 1860
Query: 1861 STFDTQITKKMGYYKILDVMYSRLPKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCY 1920
STFDTQITKKMGYYKILDVMYSRLPKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCY
Sbjct: 1861 STFDTQITKKMGYYKILDVMYSRLPKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCY 1920
Query: 1921 DAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLLIFEN 1980
DAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLLIFEN
Sbjct: 1921 DAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLLIFEN 1980
Query: 1981 LIDLKRRYNFPVEVEVPMERKKKYIEIRKEAREAANGDSDGPSYMSSLSYLADSTLSEEM 2040
LIDLKRRYNFPVEVEVPMERKKKYIEIRKEAREAANGDSDGPSYMSSLSYLADSTLSEEM
Sbjct: 1981 LIDLKRRYNFPVEVEVPMERKKKYIEIRKEAREAANGDSDGPSYMSSLSYLADSTLSEEM 2040
Query: 2041 SQFDFSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTAL 2100
SQFDFSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTAL
Sbjct: 2041 SQFDFSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTAL 2100
Query: 2101 VKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPY 2160
VKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPY
Sbjct: 2101 VKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPY 2160
Query: 2161 AKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGLATPTGVPKDEVLANRLLNFLM 2220
AKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGLATPTGVPKDEVLANRLLNFLM
Sbjct: 2161 AKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGLATPTGVPKDEVLANRLLNFLM 2220
Query: 2221 KHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIV 2280
KHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIV
Sbjct: 2221 KHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIV 2280
Query: 2281 MANDLPPYDPQCGIQSSEYFQALVNNMSFVRYKEVYAAAAEVLGLILRYVMERKNILEES 2340
MANDLPPYDPQCGIQSSEYFQALVNNMSFVRYKEVYAAAAEVLGLILRYVMERKNILEES
Sbjct: 2281 MANDLPPYDPQCGIQSSEYFQALVNNMSFVRYKEVYAAAAEVLGLILRYVMERKNILEES 2340
Query: 2341 LCELVAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEV 2400
LCELVAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEV
Sbjct: 2341 LCELVAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEV 2400
Query: 2401 VLCRVEGMTELYFQLKSKDFVQVMRHRD-ERQKVCLDIIYKMMPKLKPVELRELLNPVVE 2459
VLCRVEGMTELYFQLKSKDFVQVMRHRD ERQKVCLDIIYKMMPKLKPVELRELLNPVVE
Sbjct: 2401 VLCRVEGMTELYFQLKSKDFVQVMRHRDDERQKVCLDIIYKMMPKLKPVELRELLNPVVE 2460
Query: 2460 FVSHPSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLI 2519
FVSHPSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLI
Sbjct: 2461 FVSHPSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLI 2520
Query: 2520 IRNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHP 2579
IRNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHP
Sbjct: 2521 IRNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHP 2580
Query: 2580 LSECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQ 2639
LSECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQ
Sbjct: 2581 LSECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQ 2640
Query: 2640 QHDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSDSLLFAHKRSERLQRAPLKSVGPDF 2699
QHDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSDSLLFAHKRSERLQRAPLKSVGPDF
Sbjct: 2641 QHDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSDSLLFAHKRSERLQRAPLKSVGPDF 2700
Query: 2700 GKKRLGLPGDEVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSE 2759
GKKRLGLPGDEVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSE
Sbjct: 2701 GKKRLGLPGDEVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSE 2760
Query: 2760 LKMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEM 2819
LKMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEM
Sbjct: 2761 LKMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEM 2820
Query: 2820 DKFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAVSAGC 2879
DKFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAVSAGC
Sbjct: 2821 DKFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAVSAGC 2880
Query: 2880 LASLQQPVGIRLLEEALLRLLPAELPAKRVRGKARLPPDVLRWVELAKLYRSIGEYDVLR 2939
LASLQQPVGIRLLEEALLRLLPAELPAKRVRGKARLPPDVLRWVELAKLYRSIGEYDVLR
Sbjct: 2881 LASLQQPVGIRLLEEALLRLLPAELPAKRVRGKARLPPDVLRWVELAKLYRSIGEYDVLR 2940
Query: 2940 GIFTSEIGTKQITQSALLAEARSDYSEAAKQYDEALNKQDWVDGEPTEAEKDFWELASLD 2999
GIFTSEIGTKQITQSALLAEARSDYSEAAKQYDEALNKQDWVDGEPTEAEKDFWELASLD
Sbjct: 2941 GIFTSEIGTKQITQSALLAEARSDYSEAAKQYDEALNKQDWVDGEPTEAEKDFWELASLD 3000
Query: 3000 CYNHLAEWKSLEYCSTASIDSENPPDLNKIWSEPFYQETYLPYMIRSKLKLLLQGEADQS 3059
CYNHLAEWKSLEYCSTASIDSENPPDLNKIWSEPFYQETYLPYMIRSKLKLLLQGEADQS
Sbjct: 3001 CYNHLAEWKSLEYCSTASIDSENPPDLNKIWSEPFYQETYLPYMIRSKLKLLLQGEADQS 3060
Query: 3060 LLTFIDKAMHGELQKAILELHYSQELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVL 3119
LLTFIDKAMHGELQKAILELHYSQELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVL
Sbjct: 3061 LLTFIDKAMHGELQKAILELHYSQELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVL 3120
Query: 3120 LHQSRLTKLQSVQALTEIQEFISFISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWD 3179
LHQSRLTKLQSVQALTEIQEFISFISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWD
Sbjct: 3121 LHQSRLTKLQSVQALTEIQEFISFISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWD 3180
Query: 3180 DIITNRCFFLSKIEEKLTPLPEDNSMNVDQDGDPSDRMEVQEQEEDISSLIRSCKFSMKM 3239
DIITNRCFFLSKIEEKLTPLPEDNSMNVDQDGDPSDRMEVQEQEEDISSLIRSCKFSMKM
Sbjct: 3181 DIITNRCFFLSKIEEKLTPLPEDNSMNVDQDGDPSDRMEVQEQEEDISSLIRSCKFSMKM 3240
Query: 3240 KMIDSARKQNNFSLAMKLLKELHKESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTV 3299
KMIDSARKQNNFSLAMKLLKELHKESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTV
Sbjct: 3241 KMIDSARKQNNFSLAMKLLKELHKESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTV 3300
Query: 3300 LKTVSLLDENNVSSYLNKNILAFRDQNILLGTTYRIIANALSSEPACLAEIEEDKARRIL 3359
LKTVSLLDENNVSSYL+KNILAFRDQNILLGTTYRIIANALSSEPACLAEIEEDKARRIL
Sbjct: 3301 LKTVSLLDENNVSSYLSKNILAFRDQNILLGTTYRIIANALSSEPACLAEIEEDKARRIL 3360
Query: 3360 ELSGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFC 3419
ELSGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFC
Sbjct: 3361 ELSGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFC 3420
Query: 3420 DQQLRKEEENASVTDSAELQAYPALVVEKMLKALKLNSNEARLKFPRLLQIIERYPEETL 3479
DQQLRKEEENASV DSAELQAYPALVVEKMLKALKLNSNEARLKFPRLLQIIERYPEETL
Sbjct: 3421 DQQLRKEEENASVIDSAELQAYPALVVEKMLKALKLNSNEARLKFPRLLQIIERYPEETL 3480
Query: 3480 SLMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESY 3539
SLMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESY
Sbjct: 3481 SLMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESY 3540
Query: 3540 SFKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTP 3599
SFKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTP
Sbjct: 3541 SFKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTP 3600
Query: 3600 VNKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFN 3659
VNKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFN
Sbjct: 3601 VNKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFN 3660
Query: 3660 DITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVRIA 3719
DITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVRIA
Sbjct: 3661 DITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVRIA 3720
Query: 3720 GFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSA 3779
GFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSA
Sbjct: 3721 GFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSA 3780
Query: 3780 CSQRALQLRTYSVVPMTS-------------------------------SDPRAPPCEYK 3808
CSQRALQLRTYSVVPMTS SDPRAPPCEYK
Sbjct: 3781 CSQRALQLRTYSVVPMTSRLGLIEWLENTVTLKDLLLNTMSQEEKAAYLSDPRAPPCEYK 3840
Query: 3809 DWLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLAL 3868
DWLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLAL
Sbjct: 3841 DWLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLAL 3900
Query: 3869 RSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMP 3928
RSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMP
Sbjct: 3901 RSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMP 3960
Query: 3929 FRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKM 3988
FRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKM
Sbjct: 3961 FRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKM 4020
Query: 3989 LKKGGSWIQEINVAEKNWYPRQKICYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAV 4048
LKKGGSWIQEINVAEKNWYPRQKICYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAV
Sbjct: 4021 LKKGGSWIQEINVAEKNWYPRQKICYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAV 4080
Query: 4049 ARGSKDHNIRAQEPESGLSEETQVKCLMDQATDPNILGRTWEGWEPWM 4096
ARGSKDHNIRAQEPESGLSEETQVKCLMDQATDPNILGRTWEGWEPWM
Sbjct: 4081 ARGSKDHNIRAQEPESGLSEETQVKCLMDQATDPNILGRTWEGWEPWM 4128
>gi|157266317 ataxia telangiectasia and Rad3 related protein [Homo
sapiens]
Length = 2644
Score = 142 bits (357), Expect = 9e-33
Identities = 109/416 (26%), Positives = 178/416 (42%), Gaps = 83/416 (19%)
Query: 3709 KPLPEYHVRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQ 3768
+P P + IAGFD+ V ++ASL++PK+I ++G D + + + K +DLR+D R+ +
Sbjct: 2284 EPFPGHWAYIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNS 2343
Query: 3769 VMNGILAQDSACSQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDV-------- 3820
++N L +D+ +R L +RTY+V+P+ C +W+ +G +
Sbjct: 2344 LINKCLRKDAESRRRELHIRTYAVIPLNDE------CGIIEWVNNTAGLRPILTKLYKEK 2397
Query: 3821 GAYM--------LMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLALRSHF 3872
G YM ++ K A +E + FR+ + F+R P ++ + RS +
Sbjct: 2398 GVYMTGKELRQCMLPKSAALSEKLKVFREFLLPRHPPIFHEWFLRTFPDPTSWYSSRSAY 2457
Query: 3873 ASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMPFRLT 3932
S A++ + +ILG+GDRH N + TG + +DF F F VPE++PFRLT
Sbjct: 2458 CRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGETF-EVPEIVPFRLT 2516
Query: 3933 RQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKMLKKG 3992
+N M PM GL +R R L + + F+ +P +W K +K
Sbjct: 2517 HNMVNGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEW----SKPVK-- 2570
Query: 3993 GSWIQEINVAEKNWYPRQKICYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAVARGS 4052
GH KAP V +
Sbjct: 2571 ------------------------------------------GHSKAPLNETGEVVNEKA 2588
Query: 4053 KDHNIRAQEPESG------------LSEETQVKCLMDQATDPNILGRTWEGWEPWM 4096
K H + ++ G LS E V L+ +ATD N+L + + GW P+M
Sbjct: 2589 KTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEATDENLLCQMYLGWTPYM 2644
>gi|169165926 PREDICTED: similar to ataxia telangiectasia and Rad3
related protein, partial [Homo sapiens]
Length = 386
Score = 142 bits (357), Expect = 9e-33
Identities = 109/416 (26%), Positives = 178/416 (42%), Gaps = 83/416 (19%)
Query: 3709 KPLPEYHVRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQ 3768
+P P + IAGFD+ V ++ASL++PK+I ++G D + + + K +DLR+D R+ +
Sbjct: 26 EPFPGHWAYIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNS 85
Query: 3769 VMNGILAQDSACSQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDV-------- 3820
++N L +D+ +R L +RTY+V+P+ C +W+ +G +
Sbjct: 86 LINKCLRKDAESRRRELHIRTYAVIPLNDE------CGIIEWVNNTAGLRPILTKLYKEK 139
Query: 3821 GAYM--------LMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLALRSHF 3872
G YM ++ K A +E + FR+ + F+R P ++ + RS +
Sbjct: 140 GVYMTGKELRQCMLPKSAALSEKLKVFREFLLPRHPPIFHEWFLRTFPDPTSWYSSRSAY 199
Query: 3873 ASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMPFRLT 3932
S A++ + +ILG+GDRH N + TG + +DF F F VPE++PFRLT
Sbjct: 200 CRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGETF-EVPEIVPFRLT 258
Query: 3933 RQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKMLKKG 3992
+N M PM GL +R R L + + F+ +P +W K +K
Sbjct: 259 HNMVNGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEW----SKPVK-- 312
Query: 3993 GSWIQEINVAEKNWYPRQKICYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAVARGS 4052
GH KAP V +
Sbjct: 313 ------------------------------------------GHSKAPLNETGEVVNEKA 330
Query: 4053 KDHNIRAQEPESG------------LSEETQVKCLMDQATDPNILGRTWEGWEPWM 4096
K H + ++ G LS E V L+ +ATD N+L + + GW P+M
Sbjct: 331 KTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEATDENLLCQMYLGWTPYM 386
>gi|4826730 FK506 binding protein 12-rapamycin associated protein 1
[Homo sapiens]
Length = 2549
Score = 140 bits (352), Expect = 3e-32
Identities = 127/526 (24%), Positives = 239/526 (45%), Gaps = 48/526 (9%)
Query: 3486 ISSVPCWQFISW---ISHMVALLDKDQAVA---VQHSVEEITDNYPQAIVYPFIISSESY 3539
+ V Q +W I ++A +D + + + + +I +PQA++YP ++S+S
Sbjct: 1924 VEGVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYPLTVASKST 1983
Query: 3540 SFKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTP 3599
+ + +K + + + L +Q + ++L +L+ + ++ E ++
Sbjct: 1984 TTARHNAANKILKNMCEHSNTL-----VQQAMMVSEELIRVAILWHEMWHEGLEEASRLY 2038
Query: 3600 VNKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGK------EFDKHFGKGGSKLLRM 3653
++N++ M+E + + F Q +G+ E+ + + K G+
Sbjct: 2039 FGERNVKGMFEVLEPLHAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGN----- 2093
Query: 3654 KLSDFNDITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRN-ELEIPGQYDGRGKPLP 3712
+ D ++ + SK L K+ R+ EL +PG YD +P+
Sbjct: 2094 -VKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDPN-QPI- 2150
Query: 3713 EYHVRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNG 3772
+RI + V+ S +RP+++ + G + E FL+KG EDLRQD+RV QLF ++N
Sbjct: 2151 ---IRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNT 2207
Query: 3773 ILAQDSACSQRALQLRTYSVVPMTSSDPR---APPCE-----YKDWLTK----MSGKHDV 3820
+LA D ++ L ++ Y+V+P++++ P C+ +D+ K ++ +H +
Sbjct: 2208 LLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRI 2267
Query: 3821 GAYMLM-YKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALI 3879
M Y + V F + D L + S S E + R+++ S A++
Sbjct: 2268 MLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVM 2327
Query: 3880 CISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLM 3939
+ +ILG+GDRH +N M+ +G ++ IDFG F A PE +PFRLTR N
Sbjct: 2328 SMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTN-- 2385
Query: 3940 LPMKETGL--MYSIMVH-ALRAFRSDPGLLTNTMDVFVKEPSFDWK 3982
M+ TGL Y I H + R + ++ FV +P +W+
Sbjct: 2386 -AMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWR 2430
>gi|20336199 ataxia telangiectasia mutated isoform 2 [Homo sapiens]
Length = 1708
Score = 112 bits (279), Expect = 1e-23
Identities = 105/413 (25%), Positives = 171/413 (41%), Gaps = 69/413 (16%)
Query: 3716 VRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILA 3775
V I F + + PK I G D +E LVKG +DLRQD ++Q+FQ+ N +L
Sbjct: 1333 VTIQSFKAEFRLAGGVNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQ 1392
Query: 3776 QDSACSQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDVGAYMLMYK-GANRTE 3834
+++ +R L + TY VVP++ +W T G +G +++ + GA++
Sbjct: 1393 RNTETRKRKLTICTYKVVPLSQRSG------VLEWCT---GTVPIGEFLVNNEDGAHKRY 1443
Query: 3835 TVTSFRKRE-SKVPADLLKRAF----------------------VRMSTSPEAFLALRSH 3871
F + K ++ K++F + P + R
Sbjct: 1444 RPNDFSAFQCQKKMMEVQKKSFEEKYEVFMDVCQNFQPVFRYFCMEKFLDPAIWFEKRLA 1503
Query: 3872 FASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMPFRL 3931
+ S A I +ILG+GDRH+ N ++ ++ ++ ID G AF + LP PE +PFRL
Sbjct: 1504 YTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQG-KILPTPETVPFRL 1562
Query: 3932 TRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKMLKK 3991
TR ++ M G+ + R+ L ++V + +P FDW K L
Sbjct: 1563 TRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQETLLTIVEVLLYDPLFDWTMNPLKAL-- 1620
Query: 3992 GGSWIQEINVAEKNWYPRQKI--CYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAVA 4049
++Q+ E +P KR L+ + + E +L
Sbjct: 1621 ---YLQQRPEDETELHPTLNADDQECKRNLSDIDQSFNKVAERVL--------------- 1662
Query: 4050 RGSKDHNIRAQEPESGLSEET------QVKCLMDQATDPNILGRTWEGWEPWM 4096
+R QE G+ E T QV L+ QA DP L R + GW+ W+
Sbjct: 1663 -------MRLQEKLKGVEEGTVLSVGGQVNLLIQQAIDPKNLSRLFPGWKAWV 1708
>gi|71902540 ataxia telangiectasia mutated isoform 1 [Homo sapiens]
Length = 3056
Score = 112 bits (279), Expect = 1e-23
Identities = 105/413 (25%), Positives = 171/413 (41%), Gaps = 69/413 (16%)
Query: 3716 VRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILA 3775
V I F + + PK I G D +E LVKG +DLRQD ++Q+FQ+ N +L
Sbjct: 2681 VTIQSFKAEFRLAGGVNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQ 2740
Query: 3776 QDSACSQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDVGAYMLMYK-GANRTE 3834
+++ +R L + TY VVP++ +W T G +G +++ + GA++
Sbjct: 2741 RNTETRKRKLTICTYKVVPLSQRSG------VLEWCT---GTVPIGEFLVNNEDGAHKRY 2791
Query: 3835 TVTSFRKRE-SKVPADLLKRAF----------------------VRMSTSPEAFLALRSH 3871
F + K ++ K++F + P + R
Sbjct: 2792 RPNDFSAFQCQKKMMEVQKKSFEEKYEVFMDVCQNFQPVFRYFCMEKFLDPAIWFEKRLA 2851
Query: 3872 FASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMPFRL 3931
+ S A I +ILG+GDRH+ N ++ ++ ++ ID G AF + LP PE +PFRL
Sbjct: 2852 YTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQG-KILPTPETVPFRL 2910
Query: 3932 TRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKMLKK 3991
TR ++ M G+ + R+ L ++V + +P FDW K L
Sbjct: 2911 TRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQETLLTIVEVLLYDPLFDWTMNPLKAL-- 2968
Query: 3992 GGSWIQEINVAEKNWYPRQKI--CYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAVA 4049
++Q+ E +P KR L+ + + E +L
Sbjct: 2969 ---YLQQRPEDETELHPTLNADDQECKRNLSDIDQSFNKVAERVL--------------- 3010
Query: 4050 RGSKDHNIRAQEPESGLSEET------QVKCLMDQATDPNILGRTWEGWEPWM 4096
+R QE G+ E T QV L+ QA DP L R + GW+ W+
Sbjct: 3011 -------MRLQEKLKGVEEGTVLSVGGQVNLLIQQAIDPKNLSRLFPGWKAWV 3056
>gi|169218268 PREDICTED: similar to Serine-protein kinase ATM, partial
[Homo sapiens]
Length = 2934
Score = 112 bits (279), Expect = 1e-23
Identities = 105/413 (25%), Positives = 171/413 (41%), Gaps = 69/413 (16%)
Query: 3716 VRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILA 3775
V I F + + PK I G D +E LVKG +DLRQD ++Q+FQ+ N +L
Sbjct: 2559 VTIQSFKAEFRLAGGVNLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQ 2618
Query: 3776 QDSACSQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDVGAYMLMYK-GANRTE 3834
+++ +R L + TY VVP++ +W T G +G +++ + GA++
Sbjct: 2619 RNTETRKRKLTICTYKVVPLSQRSG------VLEWCT---GTVPIGEFLVNNEDGAHKRY 2669
Query: 3835 TVTSFRKRE-SKVPADLLKRAF----------------------VRMSTSPEAFLALRSH 3871
F + K ++ K++F + P + R
Sbjct: 2670 RPNDFSAFQCQKKMMEVQKKSFEEKYEVFMDVCQNFQPVFRYFCMEKFLDPAIWFEKRLA 2729
Query: 3872 FASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMPFRL 3931
+ S A I +ILG+GDRH+ N ++ ++ ++ ID G AF + LP PE +PFRL
Sbjct: 2730 YTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQG-KILPTPETVPFRL 2788
Query: 3932 TRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKMLKK 3991
TR ++ M G+ + R+ L ++V + +P FDW K L
Sbjct: 2789 TRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQETLLTIVEVLLYDPLFDWTMNPLKAL-- 2846
Query: 3992 GGSWIQEINVAEKNWYPRQKI--CYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAVA 4049
++Q+ E +P KR L+ + + E +L
Sbjct: 2847 ---YLQQRPEDETELHPTLNADDQECKRNLSDIDQSFDKVAERVL--------------- 2888
Query: 4050 RGSKDHNIRAQEPESGLSEET------QVKCLMDQATDPNILGRTWEGWEPWM 4096
+R QE G+ E T QV L+ QA DP L R + GW+ W+
Sbjct: 2889 -------MRLQEKLKGVEEGTVLSVGGQVNLLIQQAIDPKNLSRLFPGWKAWV 2934
>gi|62243658 PI-3-kinase-related kinase SMG-1 [Homo sapiens]
Length = 3661
Score = 95.1 bits (235), Expect = 1e-18
Identities = 88/378 (23%), Positives = 150/378 (39%), Gaps = 77/378 (20%)
Query: 3658 FNDITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVR 3717
F +I L + K + L+E SPW++ E+ +PG+ R V
Sbjct: 2071 FKEIMLSLQQRAQKRASYILRLEEISPWLA----AMTNTEIALPGEVSARDT------VT 2120
Query: 3718 IAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQD 3777
I +T++ + +PK+++ G D + +P+L KG EDL D+R+ Q ++N + A
Sbjct: 2121 IHSVGGTITILPTKTKPKKLLFLGSDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFATI 2180
Query: 3778 SACSQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDVGAYMLMYKGANRTETVT 3837
+ R YSV P+ + R+ ++ D T + G +YK + E
Sbjct: 2181 NRQETPRFHARHYSVTPLGT---RSGLIQWVDGATPLFG---------LYKRWQQREAAL 2228
Query: 3838 SFRKRE--------------------SKV------------------PADLLKRAFVR-M 3858
+K + SK+ P ++K M
Sbjct: 2229 QAQKAQDSYQTPQNPGIVPRPSELYYSKIGPALKTVGLSLDVSRRDWPLHVMKAVLEELM 2288
Query: 3859 STSPEAFLA---------------LRSHFASSHALICISHWILGIGDRHLNNFMVAMETG 3903
+P LA + +A S A++ + +I+G+GDRHL+N ++ M TG
Sbjct: 2289 EATPPNLLAKELWSSCTTPDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTG 2348
Query: 3904 GVIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDP 3963
V+ ID+ F + L VPE +PFR+T+ + G+ L R
Sbjct: 2349 EVVHIDYNVCFEKG-KSLRVPEKVPFRMTQNIETALGVTGVEGVFRLSCEQVLHIMRRGR 2407
Query: 3964 GLLTNTMDVFVKEPSFDW 3981
L ++ FV +P DW
Sbjct: 2408 ETLLTLLEAFVYDPLVDW 2425
>gi|34761064 catalytic phosphatidylinositol 3-kinase 3 [Homo sapiens]
Length = 887
Score = 68.2 bits (165), Expect = 2e-10
Identities = 70/284 (24%), Positives = 119/284 (41%), Gaps = 41/284 (14%)
Query: 3644 GKGGSKLLRMKLSDFNDITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQ 3703
G +++R L+ + L+ M + GN K+ + +++ L + E
Sbjct: 531 GDKSVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKK-----KNERLQALLGDNEKMNL 585
Query: 3704 YDGRGKPLP-EYHVRIAGF-DERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQ 3761
D PLP E V+I G E T+ S P ++ + D ++P + K G+DLRQDQ
Sbjct: 586 SDVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTEDGGKYPVIFKHGDDLRQDQ 645
Query: 3762 RVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDVG 3821
+ Q+ +M+ +L +++ L+L Y V+ S KH
Sbjct: 646 LILQIISLMDKLLRKENL----DLKLTPYKVL-------------------ATSTKHGFM 682
Query: 3822 AYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLA-LRSHFASSHALIC 3880
++ A +T S + R + P A + + S A C
Sbjct: 683 QFIQSVPVAEVLDTEGSIQN---------FFRKYAPSENGPNGISAEVMDTYVKSCAGYC 733
Query: 3881 ISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVP 3924
+ +ILG+GDRHL+N ++ +TG + IDFG+ G + LP P
Sbjct: 734 VITYILGVGDRHLDNLLLT-KTGKLFHIDFGYILGRDPKPLPPP 776
>gi|4507691 transformation/transcription domain-associated protein
[Homo sapiens]
Length = 3830
Score = 67.8 bits (164), Expect = 2e-10
Identities = 119/583 (20%), Positives = 220/583 (37%), Gaps = 105/583 (18%)
Query: 3489 VPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPF--------IISSESYS 3540
VP Q+++WI ++ L + + + + ++ YPQA+ +P I E Y
Sbjct: 3197 VPPIQWLAWIPQLLTCLVGSEGKLLLNLISQVGRVYPQAVYFPIRTLYLTLKIEQRERYK 3256
Query: 3541 ------------FKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWS 3588
++ + H +E + S L+ G++ + ++W
Sbjct: 3257 SDPGPIRATAPMWRCSRIMHMQRELHPTLLSSLE--GIVDQMV----------WFRENWH 3304
Query: 3589 NDVRAELAKTPVNKKNIEKMYERMY---AALGDPK-APGLGAFRRKFIQTFGKEFDK--- 3641
+V +L ++ + K Y + A+ D K P F +K + TFG +
Sbjct: 3305 EEVLRQL------QQGLAKCYSVAFEKSGAVSDAKITPHTLNFVKKLVSTFGVGLENVSN 3358
Query: 3642 ---HFGKGGSKLLRMKLSDFNDITNMLLLK----MNKDSKPPGNLK------ECSPWMS- 3687
F S+ L + LK + D PG++K + W+
Sbjct: 3359 VSTMFSSAASESLARRAQATAQDPVFQKLKGQFTTDFDFSVPGSMKLHNLISKLKKWIKI 3418
Query: 3688 --------------DFKVEFLRN------ELEIPGQYDGRGKPLP-EYHVRIAGFDERVT 3726
+ K FL N E+EIPG++ P P Y+++IA F RV
Sbjct: 3419 LEAKTKQLPKFFLIEEKCRFLSNFSAQTAEVEIPGEFL---MPKPTHYYIKIARFMPRVE 3475
Query: 3727 VMASLRRP-KRIIIRGHDEREHPFLVKGGEDL---RQDQRVEQLFQVMNGILAQDSACSQ 3782
++ +R+ IRGH+ + +P+LV L R+++RV QL +++N L + ++
Sbjct: 3476 IVQKHNTAARRLYIRGHNGKIYPYLVMNDACLTESRREERVLQLLRLLNPCLEKRKETTK 3535
Query: 3783 RALQL---RTYSVVP---MTSSDPRAPPCE--YKDWLTKMSGKHD--VGAYM-----LMY 3827
R L R +V P + +P + YK K +HD + Y +
Sbjct: 3536 RHLFFTVPRVVAVSPQMRLVEDNPSSLSLVEIYKQRCAKKGIEHDNPISRYYDRLATVQA 3595
Query: 3828 KGANRTETVTSFRKRE---SKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHW 3884
+G + V +E + VP +LK + + + R F ALI + +
Sbjct: 3596 RGTQASHQVLRDILKEVQSNMVPRSMLKEWALHTFPNATDYWTFRKMFTIQLALIGFAEF 3655
Query: 3885 ILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKE 3944
+L + + +A +TG + F AT L +PFRLT + +
Sbjct: 3656 VLHLNRLNPEMLQIAQDTGKLNVAYFRFDINDATGDLDANRPVPFRLTPNISEFLTTIGV 3715
Query: 3945 TGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQK 3987
+G + + M+ R F + + +++ W Q+
Sbjct: 3716 SGPLTASMIAVARCFAQPNFKVDGILKTVLRDEIIAWHKKTQE 3758
>gi|21237725 phosphoinositide-3-kinase, catalytic, gamma polypeptide
[Homo sapiens]
Length = 1102
Score = 66.6 bits (161), Expect = 5e-10
Identities = 60/223 (26%), Positives = 92/223 (41%), Gaps = 32/223 (14%)
Query: 3723 ERVTVMASLRRPKRIIIRGHD-----EREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQD 3777
E+ VMAS ++P + + D + K G+DLRQD + Q+ ++M I +
Sbjct: 799 EKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQDMLILQILRIMESIWETE 858
Query: 3778 SACSQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDVGAYMLMYKGANRTETVT 3837
S L L Y + S +G ++ +
Sbjct: 859 SL----DLCLLPYGCI---------------------STGDKIGMIEIVKDATTIAKIQQ 893
Query: 3838 SFRKRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFM 3897
S ++L S + E F A F S A C++ ++LGIGDRH +N M
Sbjct: 894 STVGNTGAFKDEVLNHWLKEKSPTEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIM 953
Query: 3898 VAMETGGVIGIDFGHAFGSATQFLPV-PELMPFRLTRQFINLM 3939
+ ETG + IDFGH G+ FL + E +PF LT F+ +M
Sbjct: 954 IT-ETGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVM 995
>gi|156564405 catalytic phosphatidylinositol 3-kinase delta [Homo
sapiens]
Length = 1044
Score = 61.2 bits (147), Expect = 2e-08
Identities = 60/222 (27%), Positives = 95/222 (42%), Gaps = 31/222 (13%)
Query: 3723 ERVTVMASLRRPKRIIIRGHDEREHP---FLVKGGEDLRQDQRVEQLFQVMNGILAQDSA 3779
E+ T M S +P I+ + + K G+DLRQD Q+ Q+M+ + Q+
Sbjct: 747 EQCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGL 806
Query: 3780 CSQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMS-GKHDVGAYMLMYKGANRTETVTS 3838
L++ Y +P D + + K ++ A K A
Sbjct: 807 ----DLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLNKSNMAATAAFNKDA-------L 855
Query: 3839 FRKRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFMV 3898
+SK P + L RA F S A C++ ++LGIGDRH +N M+
Sbjct: 856 LNWLKSKNPGEALDRAI--------------EEFTLSCAGYCVATYVLGIGDRHSDNIMI 901
Query: 3899 AMETGGVIGIDFGHAFGS-ATQFLPVPELMPFRLTRQFINLM 3939
E+G + IDFGH G+ T+F E +PF LT F++++
Sbjct: 902 -RESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVI 942
>gi|5453894 catalytic phosphatidylinositol 3-kinase beta [Homo
sapiens]
Length = 1070
Score = 56.2 bits (134), Expect = 6e-07
Identities = 55/197 (27%), Positives = 86/197 (43%), Gaps = 38/197 (19%)
Query: 3750 LVKGGEDLRQDQRVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSSDPRAPPCEYKD 3809
+ K G+DLRQD Q+ ++M D + L LR + + D
Sbjct: 803 IFKNGDDLRQDMLTLQMLRLM------DLLWKEAGLDLRMLPYGCLATGD---------- 846
Query: 3810 WLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPA------DLLKRAFVRMSTSPE 3863
SG +V + +ET+ + S V A D L ++ +
Sbjct: 847 ----RSGLIEV---------VSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDD 893
Query: 3864 AFLALRSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGS-ATQFLP 3922
A+ F S A C++ ++LGIGDRH +N MV +TG + IDFGH G+ ++F
Sbjct: 894 LDRAIEE-FTLSCAGYCVASYVLGIGDRHSDNIMV-KKTGQLFHIDFGHILGNFKSKFGI 951
Query: 3923 VPELMPFRLTRQFINLM 3939
E +PF LT FI+++
Sbjct: 952 KRERVPFILTYDFIHVI 968
>gi|169218238 PREDICTED: similar to ataxia telangiectasia and Rad3
related protein, partial [Homo sapiens]
Length = 2105
Score = 51.6 bits (122), Expect = 2e-05
Identities = 23/63 (36%), Positives = 42/63 (66%)
Query: 3709 KPLPEYHVRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQ 3768
+P P + IAGFD+ V ++ASL++PK+I ++G D + + + K +DLR+D R+ +
Sbjct: 2042 EPFPGHWAYIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNS 2101
Query: 3769 VMN 3771
++N
Sbjct: 2102 LIN 2104
>gi|4505809 catalytic phosphatidylinositol 4-kinase beta [Homo
sapiens]
Length = 828
Score = 47.8 bits (112), Expect = 2e-04
Identities = 29/81 (35%), Positives = 47/81 (58%), Gaps = 2/81 (2%)
Query: 3859 STSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSAT 3918
S + EAFL+ + +F S A C+ ++L + DRH N ++ E G +I IDFG S+
Sbjct: 652 SYTTEAFLSAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAE-GHIIHIDFGFILSSSP 710
Query: 3919 QFLPVPELMPFRLTRQFINLM 3939
+ L E F+LT +F+++M
Sbjct: 711 RNLGF-ETSAFKLTTEFVDVM 730
>gi|54792082 phosphoinositide-3-kinase, catalytic, alpha polypeptide
[Homo sapiens]
Length = 1068
Score = 45.8 bits (107), Expect = 9e-04
Identities = 57/221 (25%), Positives = 90/221 (40%), Gaps = 33/221 (14%)
Query: 3723 ERVTVMASLRRPKRIIIRGHDE------REHPFLVKGGEDLRQDQRVEQLFQVMNGILAQ 3776
E +M+S +RP + D + + + K G+DLRQD Q+ ++M I
Sbjct: 767 EECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIW-- 824
Query: 3777 DSACSQRALQLRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKHDVGAYMLMYKGANRTETV 3836
+ L LR ++ D ++ T M + G KGA + +
Sbjct: 825 ----QNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGL-----KGALQFNSH 875
Query: 3837 TSFRKRESKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLNNF 3896
T + + K ++ A F S A C++ +ILGIGDRH +N
Sbjct: 876 TLHQWLKDKNKGEIYDAAI--------------DLFTRSCAGYCVATFILGIGDRHNSNI 921
Query: 3897 MVAMETGGVIGIDFGHAFG-SATQFLPVPELMPFRLTRQFI 3936
MV + G + IDFGH +F E +PF LT+ F+
Sbjct: 922 MV-KDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFL 961
>gi|194353959 phosphoinositide-3-kinase, class 2 gamma polypeptide
[Homo sapiens]
Length = 1445
Score = 45.8 bits (107), Expect = 9e-04
Identities = 49/171 (28%), Positives = 71/171 (41%), Gaps = 27/171 (15%)
Query: 3750 LVKGGEDLRQDQRVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSSDPRAPPCEYKD 3809
+ K G+DLRQD V QL QVM+ I Q+ Q + R S P
Sbjct: 919 IFKAGDDLRQDMLVLQLIQVMDNIWLQEGLDMQMIIY-RCLSTGKDQGLVQMVPDAVTLA 977
Query: 3810 WLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLALR 3869
+ + SG G + T+ + + + + AD K ALR
Sbjct: 978 KIHRHSG----------LIGPLKENTIKKWFSQHNHLKADYEK--------------ALR 1013
Query: 3870 SHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQF 3920
+ F S A C+ +ILG+ DRH +N M+ ++G + IDFG G A F
Sbjct: 1014 NFFYSC-AGWCVVTFILGVCDRHNDNIMLT-KSGHMFHIDFGKFLGHAQTF 1062
>gi|194097347 phosphoinositide-3-kinase, class 2 beta polypeptide
[Homo sapiens]
Length = 1634
Score = 44.7 bits (104), Expect = 0.002
Identities = 47/171 (27%), Positives = 72/171 (42%), Gaps = 27/171 (15%)
Query: 3750 LVKGGEDLRQDQRVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSSDPRAPPCEYKD 3809
+ K G+DLRQD Q+ ++M+ I Q+ R + R +S P E
Sbjct: 1081 IFKCGDDLRQDMLTLQMIRIMSKIWVQEGL-DMRMVIFRCFSTGRGRGMVEMIPNAET-- 1137
Query: 3810 WLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLALR 3869
L K+ +H V SF+ R AD L++ + + +
Sbjct: 1138 -LRKIQVEHGVTG---------------SFKDRPL---ADWLQKH----NPGEDEYEKAV 1174
Query: 3870 SHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQF 3920
+F S A C++ ++LGI DRH +N M+ TG + IDFG G A F
Sbjct: 1175 ENFIYSCAGCCVATYVLGICDRHNDNIML-KTTGHMFHIDFGRFLGHAQMF 1224
>gi|157671929 phosphoinositide-3-kinase, class 2 alpha polypeptide
[Homo sapiens]
Length = 1686
Score = 43.9 bits (102), Expect = 0.003
Identities = 56/232 (24%), Positives = 94/232 (40%), Gaps = 36/232 (15%)
Query: 3750 LVKGGEDLRQDQRVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSSDPRAPP--CEY 3807
+ K GEDLRQD Q+ ++M+ I ++ L LR +++ R
Sbjct: 1136 MFKVGEDLRQDMLALQMIKIMDKIWLKEG------LDLRMVIFKCLSTGRDRGMVELVPA 1189
Query: 3808 KDWLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLA 3867
D L K+ ++ V SF+ K A+ L++ + S E +
Sbjct: 1190 SDTLRKIQVEYGVTG---------------SFK---DKPLAEWLRK----YNPSEEEYEK 1227
Query: 3868 LRSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVP-EL 3926
+F S A C++ ++LGI DRH +N M+ TG + IDFG G A F +
Sbjct: 1228 ASENFIYSCAGCCVATYVLGICDRHNDNIML-RSTGHMFHIDFGKFLGHAQMFGSFKRDR 1286
Query: 3927 MPFRLTRQFINLMLPMKETGLMYSIMV----HALRAFRSDPGLLTNTMDVFV 3974
PF LT ++ ++ + + + V A R L N + + +
Sbjct: 1287 APFVLTSDMAYVINGGEKPTIRFQLFVDLCCQAYNLIRKQTNLFLNLLSLMI 1338
>gi|148886661 exportin 4 [Homo sapiens]
Length = 1151
Score = 36.2 bits (82), Expect = 0.69
Identities = 44/179 (24%), Positives = 78/179 (43%), Gaps = 25/179 (13%)
Query: 169 TVLEKVYELLGLLGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLS 228
T+ + Y+L+ + E+ P ++ E+LF++ + L+ MTS E V CL+ L+
Sbjct: 975 TLCNQYYKLITFICEIFPEKIPQLPEDLFKSLMYSLELGMTSMSSE----VCQLCLEALT 1030
Query: 229 SLLCNFTKSMEEDPQTSREIFNFVLKAIRPQIDLKRY------AVPSAGLRLFALHASQF 282
L K+ E D +F LK + + L+++ A A L LH +++
Sbjct: 1031 PLAEQCAKAQETDSPLFLATRHF-LKLVFDMLVLQKHNTEMTTAAGEAFYTLVCLHQAEY 1089
Query: 283 S---TCLLDN------YVSLFEVLLKWCAHT-----NVELKKAALSALESFLKQVSNMV 327
S LL + Y L + K A + + + K A L +LE F+ V ++
Sbjct: 1090 SELVETLLSSQQDPVIYQRLADAFNKLTASSTPPTLDRKQKMAFLKSLEEFMANVGGLL 1148
>gi|223941912 coiled-coil domain containing 135 [Homo sapiens]
Length = 874
Score = 35.8 bits (81), Expect = 0.90
Identities = 23/58 (39%), Positives = 31/58 (53%), Gaps = 10/58 (17%)
Query: 2546 SPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHPLSECEFQEYTIDSDWRFRSTVLTP 2603
+PK E H L +A NF + + + PD P+F HPL+ECE +F ST L P
Sbjct: 88 TPK-EEHLLQVADNFSRQYSHLCPDRV-PLFLHPLNECEVP--------KFVSTTLRP 135
>gi|188497683 FAST kinase domains 1 [Homo sapiens]
Length = 847
Score = 35.0 bits (79), Expect = 1.5
Identities = 31/143 (21%), Positives = 67/143 (46%), Gaps = 26/143 (18%)
Query: 280 SQFSTCLLDNYVSLFEVLLKWC--AHTNVELKKAALSALESFLKQVSNMVAKNAEMHK-N 336
S+FS+CL D ++ ++ K H N+E + LS+L + +S++++++ + N
Sbjct: 156 SEFSSCLADQHLYFSPLMGKIADIVHRNLETTQD-LSSLSVLMVNISSLISRHFQQQLVN 214
Query: 337 KLQYFMEQFYGIIRNVDSNNKELSIAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMF 396
K + + +DS+ ++ +I + ++V + Y L++RC +F
Sbjct: 215 KTELLFD-------TIDSSEVNVAKSIAKF-----------LRNVRYRYQPLLERCNNVF 256
Query: 397 LTQTDTGDY----RVYQMPSFLQ 415
L+ D D ++ + FLQ
Sbjct: 257 LSNVDHLDLDSISKILSVYKFLQ 279
>gi|4505807 phosphatidylinositol 4-kinase type 3 alpha isoform 1 [Homo
sapiens]
Length = 854
Score = 34.3 bits (77), Expect = 2.6
Identities = 43/168 (25%), Positives = 60/168 (35%), Gaps = 32/168 (19%)
Query: 3750 LVKGGEDLRQDQRVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSSDPRAPPCEYKD 3809
+ K G+D RQD Q+ + I Q R + P P C +D
Sbjct: 600 IFKVGDDCRQDMLALQIIDLFKNIF-QLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRD 658
Query: 3810 WLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLALR 3869
L + + D G Y D R + ST AF R
Sbjct: 659 QLGRQT---DFGMY-------------------------DYFTRQYGDESTL--AFQQAR 688
Query: 3870 SHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSA 3917
+F S A + ++L I DRH N M+ + G +I IDFG F S+
Sbjct: 689 YNFIRSMAAYSLLLFLLQIKDRHNGNIMLD-KKGHIIHIDFGFMFESS 735
>gi|155030226 phosphatidylinositol 4-kinase type 3 alpha isoform 2
[Homo sapiens]
Length = 2044
Score = 34.3 bits (77), Expect = 2.6
Identities = 43/168 (25%), Positives = 60/168 (35%), Gaps = 32/168 (19%)
Query: 3750 LVKGGEDLRQDQRVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSSDPRAPPCEYKD 3809
+ K G+D RQD Q+ + I Q R + P P C +D
Sbjct: 1790 IFKVGDDCRQDMLALQIIDLFKNIF-QLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRD 1848
Query: 3810 WLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLALR 3869
L + + D G Y D R + ST AF R
Sbjct: 1849 QLGRQT---DFGMY-------------------------DYFTRQYGDESTL--AFQQAR 1878
Query: 3870 SHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSA 3917
+F S A + ++L I DRH N M+ + G +I IDFG F S+
Sbjct: 1879 YNFIRSMAAYSLLLFLLQIKDRHNGNIMLD-KKGHIIHIDFGFMFESS 1925
>gi|41352697 centromere protein I [Homo sapiens]
Length = 756
Score = 34.3 bits (77), Expect = 2.6
Identities = 22/72 (30%), Positives = 39/72 (54%), Gaps = 8/72 (11%)
Query: 822 AQKGFNKVVLKHLKKTKNLSSNEAISLEEIRIRV-VQMLGSLGGQINKNLL------TVT 874
A + +K + KHLK +N++ ++ EEI I + + + G G +N +L TV
Sbjct: 80 ASQNKDKTLEKHLKTVENVAWKNGLASEEIDILLNIALSGKFGNAVNTRILKCMIPATVI 139
Query: 875 SSDEMMKSYVAW 886
S D ++K+ V+W
Sbjct: 140 SEDSVVKA-VSW 150
>gi|239757646 PREDICTED: similar to phosphatidylinositol 4-kinase type
3 alpha [Homo sapiens]
Length = 286
Score = 33.9 bits (76), Expect = 3.4
Identities = 43/168 (25%), Positives = 60/168 (35%), Gaps = 32/168 (19%)
Query: 3750 LVKGGEDLRQDQRVEQLFQVMNGILAQDSACSQRALQLRTYSVVPMTSSDPRAPPCEYKD 3809
+ K G+D RQD Q+ + I Q R + P P C +D
Sbjct: 54 IFKLGDDCRQDMLALQIIDLFKNIF-QLVGLDLFVFPYRVVATAPGCGVIECIPDCTSRD 112
Query: 3810 WLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLALR 3869
L + + D G Y D R + ST AF R
Sbjct: 113 QLGRQT---DFGMY-------------------------DYFTRQYGDESTL--AFQQAR 142
Query: 3870 SHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSA 3917
+F S A + ++L I DRH N M+ + G +I IDFG F S+
Sbjct: 143 YNFIRSMAAYSLLLFLLQIKDRHNGNIMLD-KKGHIIHIDFGFMFESS 189
>gi|122937502 transmembrane channel-like 3 [Homo sapiens]
Length = 1100
Score = 33.9 bits (76), Expect = 3.4
Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 11/95 (11%)
Query: 2093 CMAPLTALVKHMHRSL--GPPQGEE-------DSVPRDLPSWMKFLHGKLGNPIVPLNIR 2143
CM P + SL GP G+E +++ +D P W + G + +P+V L
Sbjct: 631 CMLPTIFAIVRYKPSLNCGPFSGQEKIYDIVSETIEKDFPVWFGSVVGHISSPVVILPAV 690
Query: 2144 LFLAKLVINTEEVFR--PYAKHWLSPLLQLAASEN 2176
L L L+ + + R + H L +Q A SE+
Sbjct: 691 LLLFMLIYYLQSIARSLKLSNHQLKMQIQNARSED 725
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 33.1 bits (74), Expect = 5.8
Identities = 62/277 (22%), Positives = 112/277 (40%), Gaps = 36/277 (12%)
Query: 3218 EVQEQEEDISSLIRSCKFSMKMKMIDSARKQNNFSLAMKLL----KELHKESKTRDDWLV 3273
E QE+EE+ + +++ ++ D+ +K ++ ++ L K+L K+++ L
Sbjct: 1350 EQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLE 1409
Query: 3274 SWVQSYCRLSHCRSRSQGCSEQVLTVLKTVSLLDENNVSSYLNKNILAFRDQNILLGTTY 3333
+Y +L ++R Q Q L L TV L + V+S L K F DQ LL
Sbjct: 1410 EKALAYDKLEKTKNRLQ----QELDDL-TVDLDHQRQVASNLEKKQKKF-DQ--LLAEEK 1461
Query: 3334 RIIANALSSEPACLAEIEEDKARRILELSGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEE 3393
I A AE E K + L L+ + E E + F+ ++ ++A E
Sbjct: 1462 SISARYAEERDRAEAEARE-KETKALSLARALEEALEA------KEEFERQNKQLRADME 1514
Query: 3394 EAQPPSWSCGPAAGVID----AYMTLADFCDQQLRKEEENASVTDSAELQAYPALVVEKM 3449
+ G ++ A + QL + E+ T+ A+L+
Sbjct: 1515 DLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLR---------- 1564
Query: 3450 LKALKLNSNEARLKFPRLLQIIERYPEETLSLMTKEI 3486
L++N + +F R LQ + EE L+ K++
Sbjct: 1565 ---LEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQV 1598
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 150,174,383
Number of Sequences: 37866
Number of extensions: 6678364
Number of successful extensions: 16441
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 16240
Number of HSP's gapped (non-prelim): 168
length of query: 4096
length of database: 18,247,518
effective HSP length: 123
effective length of query: 3973
effective length of database: 13,590,000
effective search space: 53993070000
effective search space used: 53993070000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 72 (32.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.