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Search of human proteins with 21359974
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21359974 vitrin [Homo sapiens]
(693 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21359974 vitrin [Homo sapiens] 1385 0.0
gi|205277471 cochlin precursor [Homo sapiens] 375 e-104
gi|4758022 cochlin precursor [Homo sapiens] 375 e-104
gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens] 184 3e-46
gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo s... 177 2e-44
gi|156616290 collagen type VI alpha 6 [Homo sapiens] 173 4e-43
gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens] 173 5e-43
gi|13699836 matrilin 4 isoform 3 precursor [Homo sapiens] 168 2e-41
gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo s... 155 1e-37
gi|240255542 alpha 3 type VI collagen isoform 2 precursor [Homo ... 155 1e-37
gi|240255540 alpha 3 type VI collagen isoform 3 precursor [Homo ... 155 1e-37
gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo ... 140 3e-33
gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens] 132 8e-31
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [... 132 1e-30
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 127 3e-29
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ... 124 2e-28
gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens] 115 1e-25
gi|62548862 matrilin 2 isoform b precursor [Homo sapiens] 115 1e-25
gi|62548860 matrilin 2 isoform a precursor [Homo sapiens] 115 1e-25
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 113 7e-25
gi|13699834 matrilin 4 isoform 2 precursor [Homo sapiens] 110 3e-24
gi|13699830 matrilin 4 isoform 1 precursor [Homo sapiens] 110 3e-24
gi|38348304 von Willebrand factor A domain containing 2 [Homo sa... 103 7e-22
gi|11321565 matrilin 3 precursor [Homo sapiens] 100 8e-21
gi|112734845 collagen, type XX, alpha 1 [Homo sapiens] 98 2e-20
gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens] 86 9e-17
gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens] 86 9e-17
gi|89191868 von Willebrand factor preproprotein [Homo sapiens] 86 1e-16
gi|34452173 integrin alpha X precursor [Homo sapiens] 85 3e-16
gi|62548866 integrin, alpha D precursor [Homo sapiens] 83 7e-16
>gi|21359974 vitrin [Homo sapiens]
Length = 693
Score = 1385 bits (3584), Expect = 0.0
Identities = 693/693 (100%), Positives = 693/693 (100%)
Query: 1 MRTVVLTMKASVIEMFLVLLVTGVHSNKETAKKIKRPKFTVPQINCDVKAGKIIDPEFIV 60
MRTVVLTMKASVIEMFLVLLVTGVHSNKETAKKIKRPKFTVPQINCDVKAGKIIDPEFIV
Sbjct: 1 MRTVVLTMKASVIEMFLVLLVTGVHSNKETAKKIKRPKFTVPQINCDVKAGKIIDPEFIV 60
Query: 61 KCPAGCQDPKYHVYGTDVYASYSSVCGAAVHSGVLDNSGGKILVRKVAGQSGYKGSYSNG 120
KCPAGCQDPKYHVYGTDVYASYSSVCGAAVHSGVLDNSGGKILVRKVAGQSGYKGSYSNG
Sbjct: 61 KCPAGCQDPKYHVYGTDVYASYSSVCGAAVHSGVLDNSGGKILVRKVAGQSGYKGSYSNG 120
Query: 121 VQSLSLPRWRESFIVLESKPKKGVTYPSALTYSSSKSPAAQAGETTKAYQRPPIPGTTAQ 180
VQSLSLPRWRESFIVLESKPKKGVTYPSALTYSSSKSPAAQAGETTKAYQRPPIPGTTAQ
Sbjct: 121 VQSLSLPRWRESFIVLESKPKKGVTYPSALTYSSSKSPAAQAGETTKAYQRPPIPGTTAQ 180
Query: 181 PVTLMQLLAVTVAVATPTTLPRPSPSAASTTSIPRPQSVGHRSQEMDLWSTATYTSSQNR 240
PVTLMQLLAVTVAVATPTTLPRPSPSAASTTSIPRPQSVGHRSQEMDLWSTATYTSSQNR
Sbjct: 181 PVTLMQLLAVTVAVATPTTLPRPSPSAASTTSIPRPQSVGHRSQEMDLWSTATYTSSQNR 240
Query: 241 PRADPGIQRQDPSGAAFQKPVGADVSLGEMDSWKPGSVLLDEGLVPKEELSTQSLEPVSL 300
PRADPGIQRQDPSGAAFQKPVGADVSLGEMDSWKPGSVLLDEGLVPKEELSTQSLEPVSL
Sbjct: 241 PRADPGIQRQDPSGAAFQKPVGADVSLGEMDSWKPGSVLLDEGLVPKEELSTQSLEPVSL 300
Query: 301 GDPNCKIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHF 360
GDPNCKIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHF
Sbjct: 301 GDPNCKIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHF 360
Query: 361 NLKTHTNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSGAPNVVVVMVDGW 420
NLKTHTNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSGAPNVVVVMVDGW
Sbjct: 361 NLKTHTNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSGAPNVVVVMVDGW 420
Query: 421 PTDKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWF 480
PTDKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWF
Sbjct: 421 PTDKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWF 480
Query: 481 GLHKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEF 540
GLHKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEF
Sbjct: 481 GLHKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEF 540
Query: 541 EISDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQL 600
EISDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQL
Sbjct: 541 EISDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQL 600
Query: 601 FKKSKPNKRKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPAR 660
FKKSKPNKRKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPAR
Sbjct: 601 FKKSKPNKRKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPAR 660
Query: 661 DHSFFVDEFDNLHQYVPRIIQNICTEFNSQPRN 693
DHSFFVDEFDNLHQYVPRIIQNICTEFNSQPRN
Sbjct: 661 DHSFFVDEFDNLHQYVPRIIQNICTEFNSQPRN 693
>gi|205277471 cochlin precursor [Homo sapiens]
Length = 550
Score = 375 bits (964), Expect = e-104
Identities = 180/389 (46%), Positives = 263/389 (67%), Gaps = 3/389 (0%)
Query: 301 GDPNCKIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHF 360
G+ +CK D++FLIDGS +IG+RRF +QK + VA L IG GP +G+VQ ++P F
Sbjct: 158 GNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEF 217
Query: 361 NLKTHTNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSGAPNVVVVMVDGW 420
LK T+++D+ AI+++ RGG SN G+A+ + FF+ G R G P VVVV +DGW
Sbjct: 218 YLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVRKGIPKVVVVFIDGW 277
Query: 421 PTDKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWF 480
P+D +EEA +ARE G+N+F +++ E V + F +KAVCR NGF+S H+ +WF
Sbjct: 278 PSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVDKAVCRNNGFFSYHMPNWF 337
Query: 481 GLHKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEF 540
G K ++PLV+++C +++ CSKTC NS +I F+IDGSSSVG NFR +L+FV+N+ K F
Sbjct: 338 GTTKYVKPLVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTF 397
Query: 541 EISDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQL 600
EISD +I AVQ+TY+QR EF F YS+K ++L I+ + Y SGGT+TG AI+F + +
Sbjct: 398 EISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNV 457
Query: 601 FK--KSKPNKRKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHP 658
F + PNK ++++TDG+SYDDV+ PA AAH G+ +++GVAWA ++L+ +A+ P
Sbjct: 458 FGPIRESPNK-NFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKP 516
Query: 659 ARDHSFFVDEFDNLHQYVPRIIQNICTEF 687
H+FF EF L V +I+ IC +F
Sbjct: 517 KESHAFFTREFTGLEPIVSDVIRGICRDF 545
Score = 85.9 bits (211), Expect = 1e-16
Identities = 43/96 (44%), Positives = 55/96 (57%)
Query: 44 INCDVKAGKIIDPEFIVKCPAGCQDPKYHVYGTDVYASYSSVCGAAVHSGVLDNSGGKIL 103
I C + I + V CP GC ++ VYG VYAS SS+CGAAVH GV+ NSGG +
Sbjct: 32 ITCFTRGLDIRKEKADVLCPGGCPLEEFSVYGNIVYASVSSICGAAVHRGVISNSGGPVR 91
Query: 104 VRKVAGQSGYKGSYSNGVQSLSLPRWRESFIVLESK 139
V + G+ Y +NG+QS L RW SF V + K
Sbjct: 92 VYSLPGRENYSSVDANGIQSQMLSRWSASFTVTKGK 127
>gi|4758022 cochlin precursor [Homo sapiens]
Length = 550
Score = 375 bits (964), Expect = e-104
Identities = 180/389 (46%), Positives = 263/389 (67%), Gaps = 3/389 (0%)
Query: 301 GDPNCKIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHF 360
G+ +CK D++FLIDGS +IG+RRF +QK + VA L IG GP +G+VQ ++P F
Sbjct: 158 GNKDCKADIAFLIDGSFNIGQRRFNLQKNFVGKVALMLGIGTEGPHVGLVQASEHPKIEF 217
Query: 361 NLKTHTNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSGAPNVVVVMVDGW 420
LK T+++D+ AI+++ RGG SN G+A+ + FF+ G R G P VVVV +DGW
Sbjct: 218 YLKNFTSAKDVLFAIKEVGFRGGNSNTGKALKHTAQKFFTVDAGVRKGIPKVVVVFIDGW 277
Query: 421 PTDKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWF 480
P+D +EEA +ARE G+N+F +++ E V + F +KAVCR NGF+S H+ +WF
Sbjct: 278 PSDDIEEAGIVAREFGVNVFIVSVAKPIPEELGMVQDVTFVDKAVCRNNGFFSYHMPNWF 337
Query: 481 GLHKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEF 540
G K ++PLV+++C +++ CSKTC NS +I F+IDGSSSVG NFR +L+FV+N+ K F
Sbjct: 338 GTTKYVKPLVQKLCTHEQMMCSKTCYNSVNIAFLIDGSSSVGDSNFRLMLEFVSNIAKTF 397
Query: 541 EISDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQL 600
EISD +I AVQ+TY+QR EF F YS+K ++L I+ + Y SGGT+TG AI+F + +
Sbjct: 398 EISDIGAKIAAVQFTYDQRTEFSFTDYSTKENVLAVIRNIRYMSGGTATGDAISFTVRNV 457
Query: 601 FK--KSKPNKRKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHP 658
F + PNK ++++TDG+SYDDV+ PA AAH G+ +++GVAWA ++L+ +A+ P
Sbjct: 458 FGPIRESPNK-NFLVIVTDGQSYDDVQGPAAAAHDAGITIFSVGVAWAPLDDLKDMASKP 516
Query: 659 ARDHSFFVDEFDNLHQYVPRIIQNICTEF 687
H+FF EF L V +I+ IC +F
Sbjct: 517 KESHAFFTREFTGLEPIVSDVIRGICRDF 545
Score = 85.9 bits (211), Expect = 1e-16
Identities = 43/96 (44%), Positives = 55/96 (57%)
Query: 44 INCDVKAGKIIDPEFIVKCPAGCQDPKYHVYGTDVYASYSSVCGAAVHSGVLDNSGGKIL 103
I C + I + V CP GC ++ VYG VYAS SS+CGAAVH GV+ NSGG +
Sbjct: 32 ITCFTRGLDIRKEKADVLCPGGCPLEEFSVYGNIVYASVSSICGAAVHRGVISNSGGPVR 91
Query: 104 VRKVAGQSGYKGSYSNGVQSLSLPRWRESFIVLESK 139
V + G+ Y +NG+QS L RW SF V + K
Sbjct: 92 VYSLPGRENYSSVDANGIQSQMLSRWSASFTVTKGK 127
>gi|4505111 matrilin 1, cartilage matrix protein [Homo sapiens]
Length = 496
Score = 184 bits (466), Expect = 3e-46
Identities = 132/459 (28%), Positives = 215/459 (46%), Gaps = 61/459 (13%)
Query: 277 SVLLDEGLVPKEELSTQSLEPVSLGDPNCKI---DLSFLIDGSTSIGKRRFRIQKQLLAD 333
S++L L+ + L + L P S G C+ DL F++D S S+ F K L+
Sbjct: 8 SLMLCSLLLLLQALCSPGLAPQSRGHL-CRTRPTDLVFVVDSSRSVRPVEFEKVKVFLSQ 66
Query: 334 VAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTNSRDLKTAIEKITQRGGLSNVGRAISF 393
V ++LD+GP +G+V Y F+L+ H + L A+ +I + G AI F
Sbjct: 67 VIESLDVGPNATRVGMVNYASTVKQEFSLRAHVSKAALLQAVRRIQPLSTGTMTGLAIQF 126
Query: 394 VTKNFFSKANGNRSGAPN---VVVVMVDGWPTDKVEEASRLARESGINIFFITIEGAAEN 450
F A G RS +P+ VV+V+ DG P D V++ S AR SG+ +F I + G+ +
Sbjct: 127 AITKAFGDAEGGRSRSPDISKVVIVVTDGRPQDSVQDVSARARASGVELFAIGV-GSVDK 185
Query: 451 E--KQYVVEPNFANKAVCRTNGFYSLHVQSWFGLHKTLQP------LVKRVCDTDRLACS 502
+Q EP + +V+S+ + K + +V +C T C
Sbjct: 186 ATLRQIASEPQDEHVD----------YVESYSVIEKLSRKFQEAFCVVSDLCATGDHDCE 235
Query: 503 KTCLNS--------------------------------ADIGFVIDGSSSVGTGNFRTVL 530
+ C++S D+ F+IDGS SV NF V
Sbjct: 236 QVCISSPGSYTCACHEGFTLNSDGKTCNVCSGGGGSSATDLVFLIDGSKSVRPENFELVK 295
Query: 531 QFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSGGTSTG 590
+F++ + ++SD ++G VQY+ R EF ++ +K DI A++ + Y GT TG
Sbjct: 296 KFISQIVDTLDVSDKLAQVGLVQYSSSVRQEFPLGRFHTKKDIKAAVRNMSYMEKGTMTG 355
Query: 591 AAINFALEQLFKKS---KPNKRKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAA 647
AA+ + ++ F S +P +K+ I+ TDGRS D + A A G +A+GV A
Sbjct: 356 AALKYLIDNSFTVSSGARPGAQKVGIVFTDGRSQDYINDAAKKAKDLGFKMFAVGVGNAV 415
Query: 648 QEELEVIATHPARDHSFFVDEFDNLHQYVPRIIQNICTE 686
++EL IA+ P +H F+ +F ++Q ++ + IC E
Sbjct: 416 EDELREIASEPVAEHYFYTADFKTINQIGKKLQKKICVE 454
Score = 86.7 bits (213), Expect = 7e-17
Identities = 54/202 (26%), Positives = 98/202 (48%), Gaps = 10/202 (4%)
Query: 301 GDPNCKIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHF 360
G + DL FLIDGS S+ F + K+ ++ + LD+ +G+VQY + F
Sbjct: 268 GGGSSATDLVFLIDGSKSVRPENFELVKKFISQIVDTLDVSDKLAQVGLVQYSSSVRQEF 327
Query: 361 NLKTHTNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSGAPNVVVVMVDGW 420
L +D+K A+ ++ + G A+ ++ N F+ ++G R GA V +V DG
Sbjct: 328 PLGRFHTKKDIKAAVRNMSYMEKGTMTGAALKYLIDNSFTVSSGARPGAQKVGIVFTDGR 387
Query: 421 PTDKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWF 480
D + +A++ A++ G +F + + A E+E + + A + FY+ ++
Sbjct: 388 SQDYINDAAKKAKDLGFKMFAVGVGNAVEDELREIASEPVAE------HYFYTADFKTIN 441
Query: 481 GLHKTLQPLVKRVC-DTDRLAC 501
+ K LQ K++C + D AC
Sbjct: 442 QIGKKLQ---KKICVEEDPCAC 460
>gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo
sapiens]
Length = 3177
Score = 177 bits (450), Expect = 2e-44
Identities = 113/361 (31%), Positives = 198/361 (54%), Gaps = 17/361 (4%)
Query: 308 DLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTN 367
D+ FL+D S +IG+ F++ ++ L DV ++L +G +VQ+ NP T F L T+
Sbjct: 39 DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRT 98
Query: 368 SRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSG--APNVVVVMVDGWPTDKV 425
+++ + I ++ GG + G+ + ++ ++ +KA G+R+G P V+VV+ DG D +
Sbjct: 99 KQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGL 158
Query: 426 EEASRLARESGINIFFITIEGAAENE-KQYVVEPNFANKAVCRTNGFYSLH--VQSWFG- 481
S + + +N+F I +E A E K+ EP N + F SLH V +
Sbjct: 159 ALPSAELKSADVNVFAIGVEDADEGALKEIASEP--LNMHMFNLENFTSLHDIVGNLVSC 216
Query: 482 LHKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFE 541
+H ++ P +R DT+ L T +SADI F+IDGS++ G+ NF +L F+ NL ++
Sbjct: 217 VHSSVSP--ERAGDTETLK-DITAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLP 273
Query: 542 ISDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSGG-TSTGAAINFALEQL 600
I R+G VQ++ E R F D YS+K +L A+K +G+ G + G A++F +E
Sbjct: 274 IGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENH 333
Query: 601 FKKSKPNK-----RKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIA 655
F ++ ++ ++++LI+ G S D++R +A V ++ +G A++ EL+ IA
Sbjct: 334 FTRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIA 393
Query: 656 T 656
T
Sbjct: 394 T 394
Score = 157 bits (397), Expect = 3e-38
Identities = 109/386 (28%), Positives = 191/386 (49%), Gaps = 28/386 (7%)
Query: 286 PKEELSTQSLEPVSLGDPNCKIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGP 345
P+ T++L+ ++ D D+ FLIDGS + G F + L ++ + L IG
Sbjct: 223 PERAGDTETLKDITAQD---SADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQI 279
Query: 346 LMGVVQYGDNPATHFNLKTHTNSRDLKTAIEKITQRGG-LSNVGRAISFVTKNFFSKANG 404
+GVVQ+ D P T F+L T++ + A++ + GG L+N+G A+ FV +N F++A G
Sbjct: 280 RVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGG 339
Query: 405 NR--SGAPNVVVVMVDGWPTDKVEEASRLARESGINIFFITIEGAAENEKQYVV-EPNFA 461
+R G P V+V++ G +D++ +++ + F + + A+ E Q++ + N
Sbjct: 340 SRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLV 399
Query: 462 NKAVCRTNGFYSLHVQSWFGLHKTLQPLVKRVCDTDRLACSKTCL------NSADIGFVI 515
F +S+ L + L P + V + T + N DI F++
Sbjct: 400 ---------FTVPEFRSFGDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLV 450
Query: 516 DGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILN 575
DGSS++G NF + F+ + + EI ++ QY R EF F+ + +K +++
Sbjct: 451 DGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVIT 510
Query: 576 AIKRVGYWSGGT-STGAAINFALEQLFKKSKPNKR-----KLMILITDGRSYDDVRIPAM 629
A++++ G TG+A++F LF S + KL++LIT G+S D++ PA
Sbjct: 511 AVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQ 570
Query: 630 AAHLKGVITYAIGVAWAAQEELEVIA 655
++ +AIG A Q ELE IA
Sbjct: 571 ELKRSSIMAFAIGNKGADQAELEEIA 596
Score = 155 bits (392), Expect = 1e-37
Identities = 114/389 (29%), Positives = 198/389 (50%), Gaps = 22/389 (5%)
Query: 306 KIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTH 365
K D+ FL+DGS+++G F + +A V Q L+IG + V QY D F TH
Sbjct: 443 KRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTH 502
Query: 366 TNSRDLKTAIEKITQRGGLS-NVGRAISFVTKNFFSKANGNRS--GAPNVVVVMVDGWPT 422
R++ TA+ K+ G + G A+ FV N F+ + G R+ G P ++V++ G
Sbjct: 503 PTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSL 562
Query: 423 DKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWFGL 482
D++ + ++ + S I F I +GA + E + + F + V F + +Q L
Sbjct: 563 DEISQPAQELKRSSIMAFAIGNKGADQAELEEIA---FDSSLVFIPAEFRAAPLQGM--L 617
Query: 483 HKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEI 542
L PL + + T + +K DI F++DGS++VG NF V FV NL +I
Sbjct: 618 PGLLAPL-RTLSGTPEVHSNKR-----DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDI 671
Query: 543 SDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSG-GTSTGAAINFALEQLF 601
+ + R+G VQ++ EF + Y +K DIL ++++ G G +TG+A+++ F
Sbjct: 672 GNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHF 731
Query: 602 KKS-----KPNKRKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIAT 656
++ + + +L++L+T G+S D A A G++T+ +G + A + ELE IA
Sbjct: 732 TEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAF 791
Query: 657 HPARDHSFFVDEFDNLHQYVPRIIQNICT 685
+P+ + +D+F +L ++IQ + T
Sbjct: 792 NPSL--VYLMDDFSSLPALPQQLIQPLTT 818
Score = 147 bits (370), Expect = 4e-35
Identities = 106/363 (29%), Positives = 177/363 (48%), Gaps = 17/363 (4%)
Query: 306 KIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTH 365
K D+ FL+DGS ++GK F + + ++ +LDIG +G+VQ+ D P T F+L T+
Sbjct: 637 KRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTY 696
Query: 366 TNSRDLKTAIEKITQRGGLS-NVGRAISFVTKNFFSKANGNR--SGAPNVVVVMVDGWPT 422
D+ + ++ +GG N G A+S+V N F++A G+R P +++++ G
Sbjct: 697 QTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSE 756
Query: 423 DKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWFGL 482
D +A+ +GI F + GA++ K + + F V + F SL
Sbjct: 757 DSYLQAANALTRAGILTFCV---GASQANKAELEQIAFNPSLVYLMDDFSSLPALP---- 809
Query: 483 HKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEI 542
+ +QPL V + DI F+ DGS+++ G F V F+ + E +
Sbjct: 810 QQLIQPLTTYVSGGVEEVPLAQPESKRDILFLFDGSANL-VGQFPVVRDFLYKIIDELNV 868
Query: 543 SDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSG-GTSTGAAINFALEQLF 601
TRI QY+ + ++E FD++ SKP+ILN +KR+ +G + G A+++A +F
Sbjct: 869 KPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIF 928
Query: 602 KKSKPNK-----RKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIAT 656
KS ++ + ++L+ GRS D V PA GV+ + A ELE I
Sbjct: 929 VKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVL 988
Query: 657 HPA 659
PA
Sbjct: 989 SPA 991
Score = 140 bits (354), Expect = 3e-33
Identities = 108/407 (26%), Positives = 192/407 (47%), Gaps = 15/407 (3%)
Query: 287 KEELSTQS--LEPVSLGDPNCKIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAG 344
+EELS L+P+ K D+ FLIDGS S G F+ + L+ + LD+G
Sbjct: 1210 REELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDT 1268
Query: 345 PLMGVVQYGDNPATHFNLKTHTNSRDLKTAIEKITQRGGLS-NVGRAISFVTKNFFSKAN 403
+ V+Q+ D+P F L H++ +++ A++++ +GG NVG A+ +V++N F +
Sbjct: 1269 TRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPL 1328
Query: 404 GNR--SGAPNVVVVMVDGWPTDKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFA 461
G+R G P +V++ G D+V++ + ++ G+ F I E + + P +
Sbjct: 1329 GSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIARNADQEELVKISLSPEYV 1388
Query: 462 NKAVCRTNGFYSLHVQSWFGLHKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSV 521
+V SL + + ++++ + R ++ADI F+ID S V
Sbjct: 1389 F-SVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGV 1447
Query: 522 GTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVG 581
F + FV+ + + I + R+G VQ++ + EF Y S+ +L+AI+R+
Sbjct: 1448 RPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLR 1507
Query: 582 YWSGG-TSTGAAINFALEQLFKKSKPNK-----RKLMILITDGRSYDDVRIPAMAAHLKG 635
G +TG A+ F LF KS ++ + ++L+ G+S DDV A G
Sbjct: 1508 LRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQVIRSSG 1567
Query: 636 VITYAIGVAWAAQEELEVIATHPARDHSFFVDEFDNLHQYVPRIIQN 682
+++ +G + EL+ I P F V EF L RI+ +
Sbjct: 1568 IVSLGVGDRNIDRTELQTITNDPRL--VFTVREFRELPNIEERIMNS 1612
Score = 122 bits (305), Expect = 1e-27
Identities = 129/504 (25%), Positives = 220/504 (43%), Gaps = 48/504 (9%)
Query: 217 QSVGHRSQEMDLWSTATYTSSQNRPRADPGIQRQDPSGAA---FQKPVGADVSLGEMDSW 273
+S G R ++ L + ++ R D SG FQ AD + E
Sbjct: 930 KSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAK-NADPAELEQIVL 988
Query: 274 KPGSVLLDEGLVPKEELSTQS---LEPVSLGDP---NCKIDLSFLIDGSTSIGKRRFRIQ 327
P +L E L +L Q L+ V G P + + D+ FL+DGS + + F +
Sbjct: 989 SPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGV-RSGFPLL 1047
Query: 328 KQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTNSRDLKTAIEKITQRGG-LSN 386
K+ + V ++LD+G + VVQY D F L ++ N +D+ A+ ++T GG N
Sbjct: 1048 KEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPN 1107
Query: 387 VGRAISFVTKNFFSKANGNR--SGAPNVVVVMVDGWPTDKVEEASRLARESGINIFFITI 444
G A+ FV +N + G+R G P +++V+ D V S + + G I I
Sbjct: 1108 TGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGI 1167
Query: 445 EGAAENEKQYV-VEPNFANKAVCRTNGFYSLHVQSWFGLHKTLQPLVKRVCDTDRLACSK 503
A E Q + P+FA + + ++ L Q + +RV R S+
Sbjct: 1168 GNADITEMQTISFIPDFA------------VAIPTFRQLGTVQQVISERVTQLTREELSR 1215
Query: 504 T-----------CLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAV 552
D+ F+IDGS S G F+ V + L ++ TR+ +
Sbjct: 1216 LQPVLQPLPSPGVGGKRDVVFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVI 1274
Query: 553 QYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSG-GTSTGAAINFALEQLFKKSKPNK--- 608
Q++ + ++EF + +SSK ++ NA++R+ G + G A+ + +FK+ ++
Sbjct: 1275 QFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEE 1334
Query: 609 --RKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFV 666
+ ++LI+ G+S D+V PA+ GV + I A QEEL I+ P ++ F V
Sbjct: 1335 GVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSP--EYVFSV 1391
Query: 667 DEFDNLHQYVPRIIQNICTEFNSQ 690
F L +++ I T + Q
Sbjct: 1392 STFRELPSLEQKLLTPITTLTSEQ 1415
Score = 121 bits (303), Expect = 2e-27
Identities = 103/390 (26%), Positives = 180/390 (46%), Gaps = 23/390 (5%)
Query: 308 DLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTN 367
D+ FLID S + F + ++ + + L+IGP+ +GVVQ+ ++ F LKT+ +
Sbjct: 1436 DIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRS 1495
Query: 368 SRDLKTAIEKITQRGGLS-NVGRAISFVTKNFFSKANGNR--SGAPNVVVVMVDGWPTDK 424
+ AI ++ RGG N G+A+ FV +N F K+ G+R G P +V+++ G D
Sbjct: 1496 QAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDD 1555
Query: 425 VEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSL-----HVQSW 479
V +++ R SGI + E Q + + V F L + +
Sbjct: 1556 VSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDP---RLVFTVREFRELPNIEERIMNS 1612
Query: 480 FGLHKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKE 539
FG P V D S+ ADI F++DGS + +F+ VL+FV+ +
Sbjct: 1613 FG-PSAATPAPPGV---DTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDT 1668
Query: 540 FEISDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSG---GTSTG---AAI 593
++G VQY + EF +S+K I++AI +V Y G T G +
Sbjct: 1669 VYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRV 1728
Query: 594 NFALEQLFKKSKPNKRKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEV 653
N + + + ++ +IT G+S +D + ++A +GV +A+GV EE+
Sbjct: 1729 NHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGK 1788
Query: 654 IATHPARDHSFFVDEFDNLHQYVPRIIQNI 683
IA++ A +F V L + ++++ +
Sbjct: 1789 IASNSAT--AFRVGNVQELSELSEQVLETL 1816
Score = 89.0 bits (219), Expect = 1e-17
Identities = 47/178 (26%), Positives = 92/178 (51%), Gaps = 5/178 (2%)
Query: 508 SADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFGFDKY 567
+ADI F++D S ++G +F+ V +F+ ++ K + + D VQ+ EF + Y
Sbjct: 37 AADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTY 96
Query: 568 SSKPDILNAIKRVGYWSGGTSTGAAINFALEQLFKKSKPNKR-----KLMILITDGRSYD 622
+K ++L+ I + Y G TG + + ++ K+ ++ ++++++TDG S D
Sbjct: 97 RTKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKD 156
Query: 623 DVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFVDEFDNLHQYVPRII 680
+ +P+ V +AIGV A + L+ IA+ P H F ++ F +LH V ++
Sbjct: 157 GLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFTSLHDIVGNLV 214
Score = 67.0 bits (162), Expect = 6e-11
Identities = 74/332 (22%), Positives = 134/332 (40%), Gaps = 25/332 (7%)
Query: 306 KIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTH 365
K D+ FL+DGS + + F+ + ++++ + +G+VQY +P F LK
Sbjct: 1637 KADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDF 1696
Query: 366 TNSRDLKTAIEKITQRGGL-SNVGRAISFVTKNFFSKANGNR--SGAPNVVVVMVDGWPT 422
+ R + AI K+ +GG +N + + N F G+R P + V+ G
Sbjct: 1697 STKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGGKSV 1756
Query: 423 DKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWFGL 482
+ ++ S + G+ +F + + E + + V L Q L
Sbjct: 1757 EDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSELSEQVLETL 1816
Query: 483 HKTL-QPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSS----VGTGNFRTVLQFVTN-L 536
H + + L V D +K C +GF DGS V F + + + N +
Sbjct: 1817 HDAMHETLCPGVTD-----AAKACNLDVILGF--DGSRDQNVFVAQKGFESKVDAILNRI 1869
Query: 537 TKEFEIS-----DTDTRIGAVQYTYEQRLE-FGFDKYSSKPDILNAIKRVGYWSGGTSTG 590
++ +S R+ V T +E F FD+Y +P++L + + T
Sbjct: 1870 SQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEY--QPEMLEKFRNMRSQHPYVLTE 1927
Query: 591 AAINFALEQLFKKSKPNKRKLMILITDGRSYD 622
+ L + F++S P+ K++I TDG D
Sbjct: 1928 DTLKVYLNK-FRQSSPDSVKVVIHFTDGADGD 1958
Score = 42.0 bits (97), Expect = 0.002
Identities = 44/176 (25%), Positives = 80/176 (45%), Gaps = 25/176 (14%)
Query: 307 IDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPL------MGVVQYG-----DN 355
ID++F++D + + +F K+ +A + + LD+ P + VVQ+ DN
Sbjct: 2618 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDN 2677
Query: 356 PA-----THFNLKTHTNSRDLKTAIEK-ITQRGGLSNVGRAISFVTKNFFSKANGNRSGA 409
+ F+L + + L + + +TQ G +G AI + +N F A R
Sbjct: 2678 ASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRD-- 2735
Query: 410 PNVVVVMVDG-WPTDKVEEASRLARESGINIFFITIEGAAE--NEKQ---YVVEPN 459
+VV+M+ G P ++EEA R+ ++ +F + G N K+ + EPN
Sbjct: 2736 LKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPN 2791
Score = 35.4 bits (80), Expect = 0.18
Identities = 28/108 (25%), Positives = 47/108 (43%), Gaps = 9/108 (8%)
Query: 147 PSALTYSSSKSPAAQAGETTKAYQRPPI---PGTTAQPVTLMQLL------AVTVAVATP 197
P+A + +K AA+ T A RPP+ P T A+PV A VAT
Sbjct: 2907 PAAAKPAPAKPVAAKPVATKMATVRPPVAVKPATAAKPVAAKPAAVRPPAAAAAKPVATK 2966
Query: 198 TTLPRPSPSAASTTSIPRPQSVGHRSQEMDLWSTATYTSSQNRPRADP 245
+PRP + + T + + S+E+ ++ ++ + RA+P
Sbjct: 2967 PEVPRPQAAKPAATKPATTKPMVKMSREVQVFEITENSAKLHWERAEP 3014
>gi|156616290 collagen type VI alpha 6 [Homo sapiens]
Length = 2263
Score = 173 bits (439), Expect = 4e-43
Identities = 122/382 (31%), Positives = 196/382 (51%), Gaps = 24/382 (6%)
Query: 308 DLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTN 367
D+ LIDGS S F K L++V +I P +G VQY D+ F + ++N
Sbjct: 436 DIYLLIDGSGSTQATDFHEMKTFLSEVVGMFNIAPHKVRVGAVQYADSWDLEFEINKYSN 495
Query: 368 SRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSG-APNVVVVMVDGWPTDKVE 426
+DL AIE I Q GG +N G A++F T + KA R P +VV+ +G D +
Sbjct: 496 KQDLGKAIENIRQMGGNTNTGAALNF-TLSLLQKAKKQRGNKVPCHLVVLTNGMSKDSIL 554
Query: 427 EASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWFGLHKTL 486
E + RE I ++ I I+ A + + + + K V +V + L
Sbjct: 555 EPANRLREEHIRVYAIGIKEANQTQLREIAGEE---KRV--------YYVHDFDALKDIR 603
Query: 487 QPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTD 546
+V+ +C + AC + ADI F++D S S+G NF + F+ NL + +I
Sbjct: 604 NQVVQEICTEE--ACKEM---KADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDR 658
Query: 547 TRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQLF---KK 603
+IG VQ++ + EF +++ S+ DI NAI ++ + T TG+A++F + Q F K
Sbjct: 659 VQIGVVQFSDINKEEFQLNRFMSQSDISNAIDQMAHIGQTTLTGSALSF-VSQYFSPTKG 717
Query: 604 SKPNKRKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHS 663
++PN RK +ILITDG + D V+ PA+ +GVI Y++GV + +LE I+ P +
Sbjct: 718 ARPNIRKFLILITDGEAQDIVKEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRP--EMV 775
Query: 664 FFVDEFDNLHQYVPRIIQNICT 685
F+V+ FD L + ++ IC+
Sbjct: 776 FYVENFDILQRIEDDLVFGICS 797
Score = 163 bits (412), Expect = 6e-40
Identities = 119/390 (30%), Positives = 187/390 (47%), Gaps = 16/390 (4%)
Query: 308 DLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTN 367
D+ FL+D S + + F K L + ALDI +G+V Y + +L N
Sbjct: 229 DVVFLLDMSINGSEENFDYLKGFLEESVSALDIKENCMRVGLVAYSNETKVINSLSMGIN 288
Query: 368 SRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRS--GAPNVVVVMVDGWPTDKV 425
++ I+ ++ R G + G AI + K FS NG+R G P + V++ D V
Sbjct: 289 KSEVLQHIQNLSPRTGKAYTGAAIKKLRKEVFSARNGSRKNQGVPQIAVLVTHRDSEDNV 348
Query: 426 EEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWFGLHKT 485
+A+ R G+ IF + IEGA++ + + + + A + V + F L + L K
Sbjct: 349 TKAAVNLRREGVTIFTLGIEGASDTQLEKIAS-HPAEQYVSKLKTFADLAAHNQTFLKKL 407
Query: 486 LQPLVKRVC------DTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKE 539
+ V +T + C T ADI +IDGS S +F + F++ +
Sbjct: 408 RNQITHTVSVFSERTETLKSGCVDT--EEADIYLLIDGSGSTQATDFHEMKTFLSEVVGM 465
Query: 540 FEISDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQ 599
F I+ R+GAVQY LEF +KYS+K D+ AI+ + G T+TGAA+NF L
Sbjct: 466 FNIAPHKVRVGAVQYADSWDLEFEINKYSNKQDLGKAIENIRQMGGNTNTGAALNFTLSL 525
Query: 600 LFKKSKPNKRKL---MILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIAT 656
L K K K+ ++++T+G S D + PA + + YAIG+ A Q +L IA
Sbjct: 526 LQKAKKQRGNKVPCHLVVLTNGMSKDSILEPANRLREEHIRVYAIGIKEANQTQLREIAG 585
Query: 657 HPARDHSFFVDEFDNLHQYVPRIIQNICTE 686
R ++V +FD L +++Q ICTE
Sbjct: 586 EEKR--VYYVHDFDALKDIRNQVVQEICTE 613
Score = 141 bits (356), Expect = 2e-33
Identities = 105/437 (24%), Positives = 207/437 (47%), Gaps = 31/437 (7%)
Query: 262 GADVSLGEMDSWKPGSVLLDEGLVPKEELSTQSLEPVSLGDPNCK----IDLSFLIDGST 317
G++V+ E S +P V E + + + + CK +D+ F+ID S
Sbjct: 759 GSNVTQLEEISGRPEMVFYVENFDILQRIEDDLVFGICSPREECKRIEVLDVVFVIDSSG 818
Query: 318 SIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTNSRDLKTAIEK 377
SI + I K + + + D+G G ++Y D+P F L ++ + ++
Sbjct: 819 SIDYDEYNIMKDFMIGLVKKADVGKNQVRFGALKYADDPEVLFYLDDFGTKLEVISVLQN 878
Query: 378 ITQRGGLSNVGRAISFVTKNFFSKANGNR--SGAPNVVVVMVDG--WPTDKVEEASRLAR 433
GG + A+ F + + F++A G+R G P V++V+ DG DK+ ++ R
Sbjct: 879 DQAMGGSTYTAEALGF-SDHMFTEARGSRLNKGVPQVLIVITDGESHDADKLNATAKALR 937
Query: 434 ESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWFGLHKTLQPLVKRV 493
+ GI + + I+GA N + + ++K V+++ GL + V
Sbjct: 938 DKGILVLAVGIDGA--NPVELLAMAGSSDKY---------FFVETFGGLKGIFSDVTASV 986
Query: 494 CDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQ 553
C++ ++ C ++ D+ F++DGS+S+ +F+ + +F+ ++ ++F++S RIGA Q
Sbjct: 987 CNSSKVDCE---IDKVDLVFLMDGSTSIQPNDFKKMKEFLASVVQDFDVSLNRVRIGAAQ 1043
Query: 554 YTYEQRLEFGFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQLFKKSKPNK----- 608
++ EF + + +I I+ + G T GAA+ +E F+ ++
Sbjct: 1044 FSDTYHPEFPLGTFIGEKEISFQIENIKQIFGNTHIGAALR-EVEHYFRPDMGSRINTGT 1102
Query: 609 RKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFVDE 668
++++++TDG+S D+V A A +G+ Y++G+ ++L I + V
Sbjct: 1103 PQVLLVLTDGQSQDEVAQAAEALRHRGIDIYSVGIGDVDDQQL--IQITGTAEKKLTVHN 1160
Query: 669 FDNLHQYVPRIIQNICT 685
FD L + RI++NICT
Sbjct: 1161 FDELKKVNKRIVRNICT 1177
Score = 140 bits (354), Expect = 3e-33
Identities = 98/387 (25%), Positives = 188/387 (48%), Gaps = 27/387 (6%)
Query: 306 KIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTH 365
K D+ FL+D S SIG F K + ++ IGP +GVVQ+ D F L
Sbjct: 620 KADIMFLVDSSGSIGPENFSKMKTFMKNLVSKSQIGPDRVQIGVVQFSDINKEEFQLNRF 679
Query: 366 TNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSGAPNVVVVMVDGWPTDKV 425
+ D+ AI+++ G + G A+SFV++ +FS G R ++++ DG D V
Sbjct: 680 MSQSDISNAIDQMAHIGQTTLTGSALSFVSQ-YFSPTKGARPNIRKFLILITDGEAQDIV 738
Query: 426 EEASRLARESGINIFFITIEGAAENEKQYVV-EPNFANKAVCRTNGFYSLHVQSWFGLHK 484
+E + + R+ G+ I+ + + G+ + + + P +V+++ L +
Sbjct: 739 KEPAVVLRQEGVIIYSVGVFGSNVTQLEEISGRPEMV------------FYVENFDILQR 786
Query: 485 TLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISD 544
LV +C + R C + + D+ FVID S S+ + + F+ L K+ ++
Sbjct: 787 IEDDLVFGIC-SPREECKR--IEVLDVVFVIDSSGSIDYDEYNIMKDFMIGLVKKADVGK 843
Query: 545 TDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQLFKKS 604
R GA++Y + + F D + +K ++++ ++ G T T A+ F+ + +F ++
Sbjct: 844 NQVRFGALKYADDPEVLFYLDDFGTKLEVISVLQNDQAMGGSTYTAEALGFS-DHMFTEA 902
Query: 605 KPNK-----RKLMILITDGRSYDDVRIPAMAAHL--KGVITYAIGVAWAAQEELEVIATH 657
+ ++ +++I+ITDG S+D ++ A A L KG++ A+G+ A +E++A
Sbjct: 903 RGSRLNKGVPQVLIVITDGESHDADKLNATAKALRDKGILVLAVGIDGA--NPVELLAMA 960
Query: 658 PARDHSFFVDEFDNLHQYVPRIIQNIC 684
+ D FFV+ F L + ++C
Sbjct: 961 GSSDKYFFVETFGGLKGIFSDVTASVC 987
Score = 111 bits (277), Expect = 3e-24
Identities = 92/374 (24%), Positives = 171/374 (45%), Gaps = 13/374 (3%)
Query: 308 DLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTN 367
D+ FL+D S +G + F K + + +L I + + QY D + F+L T
Sbjct: 27 DVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALAQYSDKLHSEFHLSTFKG 86
Query: 368 SRDLKTAIEK-ITQRGGLSNVGRAISFVTKNFFSK-ANG-NRSGAPNVVVVMVDGWPTDK 424
+ + K GG +G+A+ + +FS ANG ++ P ++VV+ D
Sbjct: 87 RSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRDKKQFPPILVVLASSESEDN 146
Query: 425 VEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWFGLHK 484
VEEAS+ R+ G+ I + ++ A+E + + F RT S+ Q+ + K
Sbjct: 147 VEEASKALRKDGVKIISVGVQKASEENLKAMATSQFHFNL--RTVRDLSMFSQNMTHIIK 204
Query: 485 TLQPLVKRVCDTDRL-ACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEIS 543
+ + D + AC + AD+ F++D S + NF + F+ +I
Sbjct: 205 DVIKYKEGAVDDIFVEACQGPSM--ADVVFLLDMSINGSEENFDYLKGFLEESVSALDIK 262
Query: 544 DTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQLFKK 603
+ R+G V Y+ E ++ +K ++L I+ + +G TGAAI +++F
Sbjct: 263 ENCMRVGLVAYSNETKVINSLSMGINKSEVLQHIQNLSPRTGKAYTGAAIKKLRKEVFSA 322
Query: 604 SKPNKR-----KLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHP 658
+++ ++ +L+T S D+V A+ +GV + +G+ A+ +LE IA+HP
Sbjct: 323 RNGSRKNQGVPQIAVLVTHRDSEDNVTKAAVNLRREGVTIFTLGIEGASDTQLEKIASHP 382
Query: 659 ARDHSFFVDEFDNL 672
A + + F +L
Sbjct: 383 AEQYVSKLKTFADL 396
Score = 93.2 bits (230), Expect = 7e-19
Identities = 89/332 (26%), Positives = 150/332 (45%), Gaps = 32/332 (9%)
Query: 306 KIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTH 365
K+DL FL+DGSTSI F+ K+ LA V Q D+ +G Q+ D F L T
Sbjct: 998 KVDLVFLMDGSTSIQPNDFKKMKEFLASVVQDFDVSLNRVRIGAAQFSDTYHPEFPLGTF 1057
Query: 366 TNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNR--SGAPNVVVVMVDGWPTD 423
+++ IE I Q G +++G A+ V +++F G+R +G P V++V+ DG D
Sbjct: 1058 IGEKEISFQIENIKQIFGNTHIGAALREV-EHYFRPDMGSRINTGTPQVLLVLTDGQSQD 1116
Query: 424 KVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWFGLH 483
+V +A+ R GI+I+ + I +++Q + A K L V ++ L
Sbjct: 1117 EVAQAAEALRHRGIDIYSVGIGDV--DDQQLIQITGTAEK---------KLTVHNFDELK 1165
Query: 484 KTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSS-----VGTGNFRTVLQFVTNLTK 538
K + +V+ +C T A C +GF + G T LQ + L
Sbjct: 1166 KVNKRIVRNICTT---AGESNCFVDVVVGFDVSTQEKGQTLLEGQPWMETYLQDI--LRA 1220
Query: 539 EFEISDTDTRIGA-VQYTYEQRLEFGFDKYSSK-----PDILNAIKRVGYWSGGTSTGAA 592
++ +G Q + ++ +KYS K +ILN++K + G + A
Sbjct: 1221 ISSLNGVSCEVGTETQVSVAFQVTNAMEKYSPKFEIYSENILNSLKDITV-KGPSLLNAN 1279
Query: 593 INFALEQLFKKSKPNKRKLMILITDGRSYDDV 624
+ +L F+ + K+++L +DG DDV
Sbjct: 1280 LLDSLWDTFQNKSAARGKVVLLFSDGLD-DDV 1310
Score = 63.5 bits (153), Expect = 6e-10
Identities = 46/197 (23%), Positives = 85/197 (43%), Gaps = 12/197 (6%)
Query: 499 LACSKTCLNS------ADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAV 552
+ CS +N AD+ F++D S +G+ +F V F+T + I R+
Sbjct: 10 IICSHISVNQDSGPEYADVVFLVDSSDRLGSKSFPFVKMFITKMISSLPIEADKYRVALA 69
Query: 553 QYTYEQRLEFGFDKYSSKPDILNAI-KRVGYWSGGTSTGAAINFALEQLFK-----KSKP 606
QY+ + EF + + +LN + K G+ G G A+ A F + K
Sbjct: 70 QYSDKLHSEFHLSTFKGRSPMLNHLRKNFGFIGGSLQIGKALQEAHRTYFSAPANGRDKK 129
Query: 607 NKRKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFV 666
+++++ S D+V + A GV ++GV A++E L+ +AT + V
Sbjct: 130 QFPPILVVLASSESEDNVEEASKALRKDGVKIISVGVQKASEENLKAMATSQFHFNLRTV 189
Query: 667 DEFDNLHQYVPRIIQNI 683
+ Q + II+++
Sbjct: 190 RDLSMFSQNMTHIIKDV 206
Score = 55.8 bits (133), Expect = 1e-07
Identities = 98/455 (21%), Positives = 177/455 (38%), Gaps = 80/455 (17%)
Query: 301 GDPNCKI---DLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIG----PAGPLMGVVQYG 353
G P C + +L F +D S + ++ F K+++A + + + + P G + ++ Y
Sbjct: 1747 GKPECPVHPTELVFALDHSRDVTEQEFERMKEMMAFLVRDIKVRENSCPVGAHIAILSYN 1806
Query: 354 DNPATHFNLKTHTNSRDLKTAIEKIT-QRGGLSN-VGRAISFVTKNFFSKANGNRSGAPN 411
+ L IE I +R S +GRA+ F+++N F + +
Sbjct: 1807 SHARHLVRFSDAYKKSQLLREIETIPYERSSASREIGRAMRFISRNVFKRTLPG-AHTRK 1865
Query: 412 VVVVMVDGWPTDKVEEASRLARESG---INIFFITIEGAAENEKQYVVEPNFANKAVCRT 468
+ G D + A E G I IT + + ++ T
Sbjct: 1866 IATFFSSGQSAD-AHSITTAAMEFGALEIIPVVITFSNVPSVRRAFAIDD---------T 1915
Query: 469 NGFYSLHVQSWFGLHKTLQPLVK-----RVCDTDRLACSKT----CLNSADIGFVIDGSS 519
F + V S L+ L + VC D +C + + D F++D S
Sbjct: 1916 GTFQVIVVPSGADYIPALERLQRCTFCYDVCKPD-ASCDQARPPPVQSYMDAAFLLDASR 1974
Query: 520 SVGTGNFRTVLQFVTNLTKEFEI------SDTDTRIGAVQYTYEQ----------RLEFG 563
++G+ F + F+ L FEI S T R+ + + R EF
Sbjct: 1975 NMGSAEFEDIRAFLGALLDHFEITPEPETSVTGDRVALLSHAPPDFLPNTQKSPVRAEFN 2034
Query: 564 FDKYSSKPDILNAI-KRVGYWSGGTSTGAAINFALEQLFKKSKPNKR--KLMILITDGRS 620
Y SK + + + V +G G A+ + L+ +F S PN R K++ +I+ G +
Sbjct: 2035 LTTYRSKRLMKRHVHESVKQLNGDAFIGHALQWTLDNVF-LSTPNLRRNKVIFVISAGET 2093
Query: 621 Y----DDVRIPAMAAHLKG--VITYAIGVAWAAQEELEVIATHP------------ARDH 662
+ ++ ++ A +G + +++G W +ELE +A+HP DH
Sbjct: 2094 SHLDGEILKKESLRAKCQGYALFVFSLGPIW-DDKELEDLASHPLDHHLVQLGRIHKPDH 2152
Query: 663 SF---FVDEFDN-----LHQYVPRIIQNICTEFNS 689
S+ FV F N +++Y P ++ C NS
Sbjct: 2153 SYGVKFVKSFINSIRRAINKYPPINLKIKCNRLNS 2187
>gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens]
Length = 2526
Score = 173 bits (438), Expect = 5e-43
Identities = 122/381 (32%), Positives = 199/381 (52%), Gaps = 24/381 (6%)
Query: 308 DLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTN 367
D+ FLIDGS+SI +++F K+ + +V + IGP +GVVQY D+ F + ++N
Sbjct: 442 DIHFLIDGSSSIQEKQFEQIKRFMLEVTEMFSIGPDKVRVGVVQYSDDTEVEFYITDYSN 501
Query: 368 SRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSGAPNVVVVMVDGWPTDKVEE 427
DL+ AI I Q G + G+A+ ++ + + S P ++V+ DG TD+V E
Sbjct: 502 DIDLRKAIFNIKQLTGGTYTGKALDYILQIIKNGMKDRMSKVPCYLIVLTDGMSTDRVVE 561
Query: 428 ASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWFGLHKTLQ 487
++ R I + + I A + E Q + A K + G Q++ L
Sbjct: 562 PAKRLRAEQITVHAVGIGAANKIELQEI-----AGKEERVSFG------QNFDALKSIKN 610
Query: 488 PLVKRVCDTDRLACSKTCLN-SADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTD 546
+V+ +C K C + ADI F++D S S+G NFR + F+ NL + +I
Sbjct: 611 EVVREIC------AEKGCEDMKADIMFLVDSSWSIGNENFRKMKIFMKNLLTKIQIGADK 664
Query: 547 TRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQLFKKSKP 606
T+IG VQ++ + + EF ++Y ++ +I +AI R+ + GT TG A+NF + Q F SK
Sbjct: 665 TQIGVVQFSDKTKEEFQLNRYFTQQEISDAIDRMSLINEGTLTGKALNF-VGQYFTHSKG 723
Query: 607 NK---RKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHS 663
+ +K +ILITDG + DDVR PA K V +++GV A + +LE I+ +
Sbjct: 724 ARLGAKKFLILITDGVAQDDVRDPARILRGKDVTIFSVGVYNANRSQLEEISGDSSL--V 781
Query: 664 FFVDEFDNLHQYVPRIIQNIC 684
F V+ FD+L ++I +C
Sbjct: 782 FHVENFDHLKALERKLIFRVC 802
Score = 148 bits (373), Expect = 2e-35
Identities = 107/390 (27%), Positives = 188/390 (48%), Gaps = 17/390 (4%)
Query: 308 DLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTN 367
DL FL+D S G +Q L ++ ++D+ +G++ Y ++ T LK+ T
Sbjct: 236 DLVFLVDESLGTGGNLRHLQT-FLENITSSMDVKENCMRLGLMSYSNSAKTISFLKSSTT 294
Query: 368 SRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNR--SGAPNVVVVMVDGWPTDKV 425
+ + I+ ++ + G SN G AI + ++ FS++ G+R G P + V++ D+V
Sbjct: 295 QSEFQQQIKNLSIQVGKSNTGAAIDQMRRDGFSESYGSRRAQGVPQIAVLVTHRPSDDEV 354
Query: 426 EEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWFGLHKT 485
+A+ R +N+F ++I+GA + + +V + + + L S L K
Sbjct: 355 HDAALNLRLEDVNVFALSIQGANNTQLEEIVSYP-PEQTISTLKSYADLETYSTKFLKKL 413
Query: 486 LQPLVKRVC------DTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKE 539
+ ++ + D+ C T ADI F+IDGSSS+ F + +F+ +T+
Sbjct: 414 QNEIWSQISTYAEQRNLDKTGCVDT--KEADIHFLIDGSSSIQEKQFEQIKRFMLEVTEM 471
Query: 540 FEISDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQ 599
F I R+G VQY+ + +EF YS+ D+ AI + +GGT TG A+++ L+
Sbjct: 472 FSIGPDKVRVGVVQYSDDTEVEFYITDYSNDIDLRKAIFNIKQLTGGTYTGKALDYILQI 531
Query: 600 LFKKSKPNKRKL---MILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIAT 656
+ K K+ +I++TDG S D V PA + + +A+G+ A + EL+ IA
Sbjct: 532 IKNGMKDRMSKVPCYLIVLTDGMSTDRVVEPAKRLRAEQITVHAVGIGAANKIELQEIAG 591
Query: 657 HPARDHSFFVDEFDNLHQYVPRIIQNICTE 686
R F FD L +++ IC E
Sbjct: 592 KEER--VSFGQNFDALKSIKNEVVREICAE 619
Score = 148 bits (373), Expect = 2e-35
Identities = 105/394 (26%), Positives = 198/394 (50%), Gaps = 28/394 (7%)
Query: 301 GDPNCKIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHF 360
G + K D+ FL+D S SIG FR K + ++ + IG +GVVQ+ D F
Sbjct: 621 GCEDMKADIMFLVDSSWSIGNENFRKMKIFMKNLLTKIQIGADKTQIGVVQFSDKTKEEF 680
Query: 361 NLKTHTNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSGAPNVVVVMVDGW 420
L + +++ AI++++ + G+A++FV + +F+ + G R GA ++++ DG
Sbjct: 681 QLNRYFTQQEISDAIDRMSLINEGTLTGKALNFVGQ-YFTHSKGARLGAKKFLILITDGV 739
Query: 421 PTDKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSL--HVQS 478
D V + +R+ R + IF + + A ++ + + +G SL HV++
Sbjct: 740 AQDDVRDPARILRGKDVTIFSVGVYNANRSQLEEI-------------SGDSSLVFHVEN 786
Query: 479 WFGLHKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTK 538
+ L + L+ RVC C + L D+ FV+D S S+ ++ +L K
Sbjct: 787 FDHLKALERKLIFRVCALH--DCKRITL--LDVVFVLDHSGSIKKQYQDHMINLTIHLVK 842
Query: 539 EFEISDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFA-- 596
+ ++ + GA++Y+ + + F + YS++ I+ +++ G T T A+ A
Sbjct: 843 KADVGRDRVQFGALKYSDQPNILFYLNTYSNRSAIIENLRKRRDTGGNTYTAKALKHANA 902
Query: 597 --LEQLFKKSKPNKRKLMILITDGRSYDDVRIPAMAAHL--KGVITYAIGVAWAAQEELE 652
E+ + K N ++++I+ITDG S+D ++ A L KG+ +A+GV A Q+ELE
Sbjct: 903 LFTEEHGSRIKQNVKQMLIVITDGESHDHDQLNDTALELRNKGITIFAVGVGKANQKELE 962
Query: 653 VIATHPARDHSFFVDEFDNLHQYVPRIIQNICTE 686
+A + ++++ +VD FD L + + +CTE
Sbjct: 963 GMAGN--KNNTIYVDNFDKLKDVFTLVQERMCTE 994
Score = 119 bits (298), Expect = 9e-27
Identities = 100/412 (24%), Positives = 187/412 (45%), Gaps = 18/412 (4%)
Query: 292 TQSLEPVSLGDPNCKIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQ 351
T++L S G D+ FL+D S +G + F K + + +L I + + Q
Sbjct: 14 TETLADQSPGPGPVYADVVFLVDSSDHLGPKSFPFVKTFINKMINSLPIEANKYRVALAQ 73
Query: 352 YGDNPATHFNLKTHTNSRDLKTAIEKITQR-GGLSNVGRAISFVTKNFFSKA-NG-NRSG 408
Y D + F+L T + ++K Q GG +G+A+ + +FS NG +R
Sbjct: 74 YSDEFHSEFHLSTFKGRSPMLNHLKKNFQFIGGSLQIGKALQEAHRTYFSAPINGRDRKQ 133
Query: 409 APNVVVVMVDGWPTDKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRT 468
P ++VV+ D+VEEAS+ ++ G+ I + ++ A+E + + +F RT
Sbjct: 134 FPPILVVLASAESEDEVEEASKALQKDGVKIISVGVQKASEENLKAMATSHFHFNL--RT 191
Query: 469 NGFYSLHVQSWFGLHKTLQPLVKRVCDTDR-----LACSKTCLNSADIGFVIDGSSSVGT 523
S Q+ + K + + D D ++C K L AD+ F++D S G
Sbjct: 192 IRDLSTFSQNMTQIIKDVTKYKEGAVDADMQVHFPISCQKDSL--ADLVFLVDESLGTG- 248
Query: 524 GNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYW 583
GN R + F+ N+T ++ + R+G + Y+ + +++ + IK +
Sbjct: 249 GNLRHLQTFLENITSSMDVKENCMRLGLMSYSNSAKTISFLKSSTTQSEFQQQIKNLSIQ 308
Query: 584 SGGTSTGAAINFALEQLFKKSKPNKR-----KLMILITDGRSYDDVRIPAMAAHLKGVIT 638
G ++TGAAI+ F +S ++R ++ +L+T S D+V A+ L+ V
Sbjct: 309 VGKSNTGAAIDQMRRDGFSESYGSRRAQGVPQIAVLVTHRPSDDEVHDAALNLRLEDVNV 368
Query: 639 YAIGVAWAAQEELEVIATHPARDHSFFVDEFDNLHQYVPRIIQNICTEFNSQ 690
+A+ + A +LE I ++P + + +L Y + ++ + E SQ
Sbjct: 369 FALSIQGANNTQLEEIVSYPPEQTISTLKSYADLETYSTKFLKKLQNEIWSQ 420
Score = 83.6 bits (205), Expect = 6e-16
Identities = 94/396 (23%), Positives = 166/396 (41%), Gaps = 43/396 (10%)
Query: 307 IDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHT 366
+D+ F++D S SI K+ L + + D+G G ++Y D P F L T++
Sbjct: 813 LDVVFVLDHSGSIKKQYQDHMINLTIHLVKKADVGRDRVQFGALKYSDQPNILFYLNTYS 872
Query: 367 NSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNR--SGAPNVVVVMVDG--WPT 422
N + + K GG + +A+ F++ +G+R +++V+ DG
Sbjct: 873 NRSAIIENLRKRRDTGGNTYTAKALKHANA-LFTEEHGSRIKQNVKQMLIVITDGESHDH 931
Query: 423 DKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWFGL 482
D++ + + R GI IF + + A + E +E NK +++V ++ L
Sbjct: 932 DQLNDTALELRNKGITIFAVGVGKANQKE----LEGMAGNKN-------NTIYVDNFDKL 980
Query: 483 HKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEI 542
+ +R+C C L AD+ F+ DGS V +F T+ F+++L F+I
Sbjct: 981 KDVFTLVQERMCTEAPEVCH---LQEADVIFLCDGSDRVSNSDFVTMTTFLSDLIDNFDI 1037
Query: 543 SDTDTRIGAVQY--TYEQRLEF--GFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALE 598
+IG Q+ Y+ +E K K I N K G+ I+FAL+
Sbjct: 1038 QSQRMKIGMAQFGSNYQSIIELKNSLTKTQWKTQIQNVSKSGGF--------PRIDFALK 1089
Query: 599 Q---LFKKSKPNKR-----KLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEE 650
+ +F +R + +++IT G DV G+ +G+ +E
Sbjct: 1090 KVSNMFNLHAGGRRNAGVPQTLVVITSGDPRYDVADAVKTLKDLGICVLVLGIGDVYKEH 1149
Query: 651 LEVIATHPARDHSFFVDEFDNLH--QYVPRIIQNIC 684
L I + + +F +FD L RII+ IC
Sbjct: 1150 LLPITGNSEKIITF--QDFDKLKNVDVKKRIIREIC 1183
Score = 67.8 bits (164), Expect = 3e-11
Identities = 82/394 (20%), Positives = 163/394 (41%), Gaps = 45/394 (11%)
Query: 303 PNCKIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIG----PAGPLMGVVQYGDNPAT 358
P +L F +D S + + F + ++ + L+I P G + +V Y +
Sbjct: 1753 PAYPTELVFALDNSYDVTEESFNKTRDIITSIVNDLNIRENNCPVGARVAMVSYNSGTSY 1812
Query: 359 HFNLKTHTNSRDLKTAIEKITQRGGLS--NVGRAISFVTKNFFSKANGNRSGAPNVVVVM 416
+ + L + +I + +VG A+ FVT+N F + + V V
Sbjct: 1813 LIRWSDYNRKKQLLQQLSQIKYQDTTEPRDVGNAMRFVTRNVFKRTYAG-ANVRRVAVFF 1871
Query: 417 VDGWPTDKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHV 476
+G + + S ++I A +E+ ++ F N T F + V
Sbjct: 1872 SNGQTASRSSIITATMEFSALDISPTVF---AFDERVFLEAFGFDN-----TGTFQVIPV 1923
Query: 477 QSWFGLHKTLQPLVKRVCDTDRLACSKTCLNSA--------DIGFVIDGSSSVGTGNFRT 528
G ++TL+ L + D+ C+ A D+ F+ID S ++ F+
Sbjct: 1924 PP-NGENQTLERLRRCALCYDK-CFPNACIREAFLPEDSYMDVVFLIDNSRNIAKDEFKA 1981
Query: 529 VLQFVTNLTKEFE------ISDTDTRIGAVQYTYEQ---------RLEFGFDKYSSKPDI 573
V V+++ F ISD+ RI + Y+ + + EF F Y ++ +
Sbjct: 1982 VKALVSSVIDNFNIASDPLISDSGDRIALLSYSPWESSRRKMGTVKTEFDFITYDNQLLM 2041
Query: 574 LNAIKRVGYWSGGTST-GAAINFALEQLFKKSK-PNKRKLMILITDGRSYDD---VRIPA 628
N I+ G +T G A+ + E LF ++ K K++ +++ G +Y+ V++ A
Sbjct: 2042 KNHIQTSFQQLNGEATIGRALLWTTENLFPETPYLRKHKVIFVVSAGENYERKEFVKMMA 2101
Query: 629 MAAHLKGVITYAIGVAWAAQEELEVIATHPARDH 662
+ A +G + + I + ++++E +A++P H
Sbjct: 2102 LRAKCQGYVIFVISLGSTRKDDMEELASYPLDQH 2135
Score = 64.7 bits (156), Expect = 3e-10
Identities = 84/411 (20%), Positives = 167/411 (40%), Gaps = 45/411 (10%)
Query: 279 LLDEGLVPKEELSTQSLEPVSLGDPNCKIDLSFLIDGSTSIGKRRFRIQKQLLADVAQAL 338
L D + +E + T++ E L + D+ FL DGS + F L+D+
Sbjct: 980 LKDVFTLVQERMCTEAPEVCHLQEA----DVIFLCDGSDRVSNSDFVTMTTFLSDLIDNF 1035
Query: 339 DIGPAGPLMGVVQYGDNPATHFNLKTHTNSRDLKTAIEKITQRGGLSNVGRAISFVTKNF 398
DI +G+ Q+G N + LK KT I+ +++ GG + A+ V+ F
Sbjct: 1036 DIQSQRMKIGMAQFGSNYQSIIELKNSLTKTQWKTQIQNVSKSGGFPRIDFALKKVSNMF 1095
Query: 399 FSKANGNR-SGAPNVVVVMVDGWPTDKVEEASRLARESGINIFFITIEGAAENEKQYVVE 457
A G R +G P +VV+ G P V +A + ++ GI + + G + K++++
Sbjct: 1096 NLHAGGRRNAGVPQTLVVITSGDPRYDVADAVKTLKDLGICVLVL---GIGDVYKEHLLP 1152
Query: 458 PNFANKAVCRTNGFYSLHVQSWFGLHKTLQPLVKRVCDTDRLACSKT-CLNSADIGFVID 516
++ + F L + +++ +C +C KT C +GF I
Sbjct: 1153 ITGNSEKIITFQDFDKLKNVD------VKKRIIREICQ----SCGKTNCFMDIVVGFDI- 1201
Query: 517 GSSSVGTGNFR----------TVLQFVTNLTKEFEISDTDTRIG-AVQYTYEQRLEFGFD 565
+ G F+ +L+ ++++ + T+ ++ A + +Q F
Sbjct: 1202 STHVQGQPLFQGHPQLESYLPGILEDISSIKGVSCGAGTEAQVSLAFKVNSDQGFPAKFQ 1261
Query: 566 KYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQLFKKSKPNKRKLMILITDG-RSYDDV 624
Y + +++ +V SG T A +L FK ++ +++++ +DG +S ++
Sbjct: 1262 IYQKA--VFDSLLQVNV-SGPTHLNAQFLRSLWDTFKDKSASRGQVLLIFSDGLQSESNI 1318
Query: 625 RIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFVDEFDNLHQY 675
+ + L+ A + L V++ + H F EF Y
Sbjct: 1319 MLENQSDRLRE----------AGLDALLVVSLNTTAHHEFSSFEFGKRFDY 1359
Score = 45.1 bits (105), Expect = 2e-04
Identities = 42/177 (23%), Positives = 77/177 (43%), Gaps = 26/177 (14%)
Query: 510 DIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDT------DTRIGAVQYT-------- 555
D+ F+ID S VG+ F+ V F+T++ F I+ T R+ + Y+
Sbjct: 2291 DVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPNT 2350
Query: 556 --YEQRLEFGFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQLFKKSKPNKRKLMI 613
LEF Y+S + + ++ +G G A+ + ++ +F PN RK +
Sbjct: 2351 EECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVF-VGTPNLRKNKV 2409
Query: 614 LI------TDGRSYDDVRIPAMAAHLKG--VITYAIGVAWAAQEELEVIATHPARDH 662
+ T+ D +R ++ A +G + ++ G +ELE +A+HP H
Sbjct: 2410 IFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSFGPK-HNDKELEELASHPLDHH 2465
Score = 41.6 bits (96), Expect = 0.002
Identities = 44/188 (23%), Positives = 75/188 (39%), Gaps = 25/188 (13%)
Query: 287 KEELSTQSLEPVSLGDPNCKIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPA--- 343
++E + EP + +D++FLID S +G F+ K + V I P
Sbjct: 2270 RKEEPDHTYEPGDVSLQEYYMDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLT 2329
Query: 344 ---GPLMGVVQY---GDNPAT-------HFNLKTHTNSRDLKTAIEKITQRGGLSNVGRA 390
G + V+ Y G P T F+L T+ + +K ++ Q G +G A
Sbjct: 2330 STLGDRVAVLSYSPPGYMPNTEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHA 2389
Query: 391 ISFVTKNFFSKANGNRSGAPNVVVVMVDGWPT-----DKVEEASRLARESGINIFFITIE 445
+ + N F G + N V+ ++ T D + S A+ G +IF +
Sbjct: 2390 LQWTIDNVFV---GTPNLRKNKVIFVISAGETNSLDKDVLRNVSLRAKCQGYSIFVFSF- 2445
Query: 446 GAAENEKQ 453
G N+K+
Sbjct: 2446 GPKHNDKE 2453
>gi|13699836 matrilin 4 isoform 3 precursor [Homo sapiens]
Length = 499
Score = 168 bits (425), Expect = 2e-41
Identities = 115/429 (26%), Positives = 190/429 (44%), Gaps = 44/429 (10%)
Query: 298 VSLGDPNCK---IDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGD 354
+ L P C +DL F+ID S S+ F +Q L + + L++GP +GV+QY
Sbjct: 21 LQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSS 80
Query: 355 NPATHFNLKTHTNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNR---SGAPN 411
+ F L+ + D++ AI + + G AI + FS A G R P
Sbjct: 81 QVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPR 140
Query: 412 VVVVMVDGWPTDKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGF 471
V V++ DG P D+V E + AR GI I+ + ++ A + + P
Sbjct: 141 VAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFL----V 196
Query: 472 YSLHVQSWFGLHKTLQPLVKRVCD----------------------------TDRLACSK 503
S + FGL + V+ +C+ D +C++
Sbjct: 197 ESFDLIQEFGLQFQSRLCVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNR 256
Query: 504 TCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFG 563
D+ ++DGS SV NF V +FV + ++S TR+G VQ++ R EF
Sbjct: 257 CREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFP 316
Query: 564 FDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQLFKKSKP------NKRKLMILITD 617
+Y + ++ A+ V Y GT TG A+ +E F +++ N ++ ++ TD
Sbjct: 317 LGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD 376
Query: 618 GRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFVDEFDNLHQYVP 677
GRS DD+ + A A +G++ YA+GV A + EL IA+ PA H + +F + +
Sbjct: 377 GRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLE 436
Query: 678 RIIQNICTE 686
+ +IC E
Sbjct: 437 NLRGSICPE 445
>gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo
sapiens]
Length = 2971
Score = 155 bits (392), Expect = 1e-37
Identities = 114/389 (29%), Positives = 198/389 (50%), Gaps = 22/389 (5%)
Query: 306 KIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTH 365
K D+ FL+DGS+++G F + +A V Q L+IG + V QY D F TH
Sbjct: 237 KRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTH 296
Query: 366 TNSRDLKTAIEKITQRGGLS-NVGRAISFVTKNFFSKANGNRS--GAPNVVVVMVDGWPT 422
R++ TA+ K+ G + G A+ FV N F+ + G R+ G P ++V++ G
Sbjct: 297 PTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSL 356
Query: 423 DKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWFGL 482
D++ + ++ + S I F I +GA + E + + F + V F + +Q L
Sbjct: 357 DEISQPAQELKRSSIMAFAIGNKGADQAELEEIA---FDSSLVFIPAEFRAAPLQGM--L 411
Query: 483 HKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEI 542
L PL + + T + +K DI F++DGS++VG NF V FV NL +I
Sbjct: 412 PGLLAPL-RTLSGTPEVHSNKR-----DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDI 465
Query: 543 SDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSG-GTSTGAAINFALEQLF 601
+ + R+G VQ++ EF + Y +K DIL ++++ G G +TG+A+++ F
Sbjct: 466 GNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHF 525
Query: 602 KKS-----KPNKRKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIAT 656
++ + + +L++L+T G+S D A A G++T+ +G + A + ELE IA
Sbjct: 526 TEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAF 585
Query: 657 HPARDHSFFVDEFDNLHQYVPRIIQNICT 685
+P+ + +D+F +L ++IQ + T
Sbjct: 586 NPSL--VYLMDDFSSLPALPQQLIQPLTT 612
Score = 154 bits (390), Expect = 2e-37
Identities = 105/364 (28%), Positives = 181/364 (49%), Gaps = 25/364 (6%)
Query: 308 DLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTN 367
D+ FLIDGS + G F + L ++ + L IG +GVVQ+ D P T F+L T++
Sbjct: 36 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYST 95
Query: 368 SRDLKTAIEKITQRGG-LSNVGRAISFVTKNFFSKANGNR--SGAPNVVVVMVDGWPTDK 424
+ A++ + GG L+N+G A+ FV +N F++A G+R G P V+V++ G +D+
Sbjct: 96 KAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDE 155
Query: 425 VEEASRLARESGINIFFITIEGAAENEKQYVV-EPNFANKAVCRTNGFYSLHVQSWFGLH 483
+ +++ + F + + A+ E Q++ + N F +S+ L
Sbjct: 156 IRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLV---------FTVPEFRSFGDLQ 206
Query: 484 KTLQPLVKRVCDTDRLACSKTCL------NSADIGFVIDGSSSVGTGNFRTVLQFVTNLT 537
+ L P + V + T + N DI F++DGSS++G NF + F+ +
Sbjct: 207 EKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVI 266
Query: 538 KEFEISDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSGGT-STGAAINFA 596
+ EI ++ QY R EF F+ + +K +++ A++++ G TG+A++F
Sbjct: 267 QRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFV 326
Query: 597 LEQLFKKSKPNKR-----KLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEEL 651
LF S + KL++LIT G+S D++ PA ++ +AIG A Q EL
Sbjct: 327 RNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAEL 386
Query: 652 EVIA 655
E IA
Sbjct: 387 EEIA 390
Score = 147 bits (370), Expect = 4e-35
Identities = 106/363 (29%), Positives = 177/363 (48%), Gaps = 17/363 (4%)
Query: 306 KIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTH 365
K D+ FL+DGS ++GK F + + ++ +LDIG +G+VQ+ D P T F+L T+
Sbjct: 431 KRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTY 490
Query: 366 TNSRDLKTAIEKITQRGGLS-NVGRAISFVTKNFFSKANGNR--SGAPNVVVVMVDGWPT 422
D+ + ++ +GG N G A+S+V N F++A G+R P +++++ G
Sbjct: 491 QTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSE 550
Query: 423 DKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWFGL 482
D +A+ +GI F + GA++ K + + F V + F SL
Sbjct: 551 DSYLQAANALTRAGILTFCV---GASQANKAELEQIAFNPSLVYLMDDFSSLPALP---- 603
Query: 483 HKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEI 542
+ +QPL V + DI F+ DGS+++ G F V F+ + E +
Sbjct: 604 QQLIQPLTTYVSGGVEEVPLAQPESKRDILFLFDGSANL-VGQFPVVRDFLYKIIDELNV 662
Query: 543 SDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSG-GTSTGAAINFALEQLF 601
TRI QY+ + ++E FD++ SKP+ILN +KR+ +G + G A+++A +F
Sbjct: 663 KPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIF 722
Query: 602 KKSKPNK-----RKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIAT 656
KS ++ + ++L+ GRS D V PA GV+ + A ELE I
Sbjct: 723 VKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVL 782
Query: 657 HPA 659
PA
Sbjct: 783 SPA 785
Score = 140 bits (354), Expect = 3e-33
Identities = 108/407 (26%), Positives = 192/407 (47%), Gaps = 15/407 (3%)
Query: 287 KEELSTQS--LEPVSLGDPNCKIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAG 344
+EELS L+P+ K D+ FLIDGS S G F+ + L+ + LD+G
Sbjct: 1004 REELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDT 1062
Query: 345 PLMGVVQYGDNPATHFNLKTHTNSRDLKTAIEKITQRGGLS-NVGRAISFVTKNFFSKAN 403
+ V+Q+ D+P F L H++ +++ A++++ +GG NVG A+ +V++N F +
Sbjct: 1063 TRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPL 1122
Query: 404 GNR--SGAPNVVVVMVDGWPTDKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFA 461
G+R G P +V++ G D+V++ + ++ G+ F I E + + P +
Sbjct: 1123 GSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIARNADQEELVKISLSPEYV 1182
Query: 462 NKAVCRTNGFYSLHVQSWFGLHKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSV 521
+V SL + + ++++ + R ++ADI F+ID S V
Sbjct: 1183 F-SVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGV 1241
Query: 522 GTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVG 581
F + FV+ + + I + R+G VQ++ + EF Y S+ +L+AI+R+
Sbjct: 1242 RPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLR 1301
Query: 582 YWSGG-TSTGAAINFALEQLFKKSKPNK-----RKLMILITDGRSYDDVRIPAMAAHLKG 635
G +TG A+ F LF KS ++ + ++L+ G+S DDV A G
Sbjct: 1302 LRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQVIRSSG 1361
Query: 636 VITYAIGVAWAAQEELEVIATHPARDHSFFVDEFDNLHQYVPRIIQN 682
+++ +G + EL+ I P F V EF L RI+ +
Sbjct: 1362 IVSLGVGDRNIDRTELQTITNDPRL--VFTVREFRELPNIEERIMNS 1406
Score = 122 bits (305), Expect = 1e-27
Identities = 129/504 (25%), Positives = 220/504 (43%), Gaps = 48/504 (9%)
Query: 217 QSVGHRSQEMDLWSTATYTSSQNRPRADPGIQRQDPSGAA---FQKPVGADVSLGEMDSW 273
+S G R ++ L + ++ R D SG FQ AD + E
Sbjct: 724 KSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAK-NADPAELEQIVL 782
Query: 274 KPGSVLLDEGLVPKEELSTQS---LEPVSLGDP---NCKIDLSFLIDGSTSIGKRRFRIQ 327
P +L E L +L Q L+ V G P + + D+ FL+DGS + + F +
Sbjct: 783 SPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGV-RSGFPLL 841
Query: 328 KQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTNSRDLKTAIEKITQRGG-LSN 386
K+ + V ++LD+G + VVQY D F L ++ N +D+ A+ ++T GG N
Sbjct: 842 KEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPN 901
Query: 387 VGRAISFVTKNFFSKANGNR--SGAPNVVVVMVDGWPTDKVEEASRLARESGINIFFITI 444
G A+ FV +N + G+R G P +++V+ D V S + + G I I
Sbjct: 902 TGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGI 961
Query: 445 EGAAENEKQYV-VEPNFANKAVCRTNGFYSLHVQSWFGLHKTLQPLVKRVCDTDRLACSK 503
A E Q + P+FA + + ++ L Q + +RV R S+
Sbjct: 962 GNADITEMQTISFIPDFA------------VAIPTFRQLGTVQQVISERVTQLTREELSR 1009
Query: 504 T-----------CLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAV 552
D+ F+IDGS S G F+ V + L ++ TR+ +
Sbjct: 1010 LQPVLQPLPSPGVGGKRDVVFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVI 1068
Query: 553 QYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSG-GTSTGAAINFALEQLFKKSKPNK--- 608
Q++ + ++EF + +SSK ++ NA++R+ G + G A+ + +FK+ ++
Sbjct: 1069 QFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEE 1128
Query: 609 --RKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFV 666
+ ++LI+ G+S D+V PA+ GV + I A QEEL I+ P ++ F V
Sbjct: 1129 GVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSP--EYVFSV 1185
Query: 667 DEFDNLHQYVPRIIQNICTEFNSQ 690
F L +++ I T + Q
Sbjct: 1186 STFRELPSLEQKLLTPITTLTSEQ 1209
Score = 121 bits (303), Expect = 2e-27
Identities = 103/390 (26%), Positives = 180/390 (46%), Gaps = 23/390 (5%)
Query: 308 DLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTN 367
D+ FLID S + F + ++ + + L+IGP+ +GVVQ+ ++ F LKT+ +
Sbjct: 1230 DIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRS 1289
Query: 368 SRDLKTAIEKITQRGGLS-NVGRAISFVTKNFFSKANGNR--SGAPNVVVVMVDGWPTDK 424
+ AI ++ RGG N G+A+ FV +N F K+ G+R G P +V+++ G D
Sbjct: 1290 QAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDD 1349
Query: 425 VEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSL-----HVQSW 479
V +++ R SGI + E Q + + V F L + +
Sbjct: 1350 VSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDP---RLVFTVREFRELPNIEERIMNS 1406
Query: 480 FGLHKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKE 539
FG P V D S+ ADI F++DGS + +F+ VL+FV+ +
Sbjct: 1407 FG-PSAATPAPPGV---DTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDT 1462
Query: 540 FEISDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSG---GTSTG---AAI 593
++G VQY + EF +S+K I++AI +V Y G T G +
Sbjct: 1463 VYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRV 1522
Query: 594 NFALEQLFKKSKPNKRKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEV 653
N + + + ++ +IT G+S +D + ++A +GV +A+GV EE+
Sbjct: 1523 NHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGK 1582
Query: 654 IATHPARDHSFFVDEFDNLHQYVPRIIQNI 683
IA++ A +F V L + ++++ +
Sbjct: 1583 IASNSAT--AFRVGNVQELSELSEQVLETL 1610
Score = 96.7 bits (239), Expect = 7e-20
Identities = 53/156 (33%), Positives = 92/156 (58%), Gaps = 6/156 (3%)
Query: 507 NSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFGFDK 566
+SADI F+IDGS++ G+ NF +L F+ NL ++ I R+G VQ++ E R F D
Sbjct: 33 DSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDT 92
Query: 567 YSSKPDILNAIKRVGYWSGG-TSTGAAINFALEQLFKKSKPNK-----RKLMILITDGRS 620
YS+K +L A+K +G+ G + G A++F +E F ++ ++ ++++LI+ G S
Sbjct: 93 YSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPS 152
Query: 621 YDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIAT 656
D++R +A V ++ +G A++ EL+ IAT
Sbjct: 153 SDEIRYGVVALKQASVFSFGLGAQAASRAELQHIAT 188
Score = 67.0 bits (162), Expect = 6e-11
Identities = 74/332 (22%), Positives = 134/332 (40%), Gaps = 25/332 (7%)
Query: 306 KIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTH 365
K D+ FL+DGS + + F+ + ++++ + +G+VQY +P F LK
Sbjct: 1431 KADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDF 1490
Query: 366 TNSRDLKTAIEKITQRGGL-SNVGRAISFVTKNFFSKANGNR--SGAPNVVVVMVDGWPT 422
+ R + AI K+ +GG +N + + N F G+R P + V+ G
Sbjct: 1491 STKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGGKSV 1550
Query: 423 DKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWFGL 482
+ ++ S + G+ +F + + E + + V L Q L
Sbjct: 1551 EDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSELSEQVLETL 1610
Query: 483 HKTL-QPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSS----VGTGNFRTVLQFVTN-L 536
H + + L V D +K C +GF DGS V F + + + N +
Sbjct: 1611 HDAMHETLCPGVTD-----AAKACNLDVILGF--DGSRDQNVFVAQKGFESKVDAILNRI 1663
Query: 537 TKEFEIS-----DTDTRIGAVQYTYEQRLE-FGFDKYSSKPDILNAIKRVGYWSGGTSTG 590
++ +S R+ V T +E F FD+Y +P++L + + T
Sbjct: 1664 SQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEY--QPEMLEKFRNMRSQHPYVLTE 1721
Query: 591 AAINFALEQLFKKSKPNKRKLMILITDGRSYD 622
+ L + F++S P+ K++I TDG D
Sbjct: 1722 DTLKVYLNK-FRQSSPDSVKVVIHFTDGADGD 1752
Score = 42.0 bits (97), Expect = 0.002
Identities = 44/176 (25%), Positives = 80/176 (45%), Gaps = 25/176 (14%)
Query: 307 IDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPL------MGVVQYG-----DN 355
ID++F++D + + +F K+ +A + + LD+ P + VVQ+ DN
Sbjct: 2412 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDN 2471
Query: 356 PA-----THFNLKTHTNSRDLKTAIEK-ITQRGGLSNVGRAISFVTKNFFSKANGNRSGA 409
+ F+L + + L + + +TQ G +G AI + +N F A R
Sbjct: 2472 ASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRD-- 2529
Query: 410 PNVVVVMVDG-WPTDKVEEASRLARESGINIFFITIEGAAE--NEKQ---YVVEPN 459
+VV+M+ G P ++EEA R+ ++ +F + G N K+ + EPN
Sbjct: 2530 LKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPN 2585
Score = 35.4 bits (80), Expect = 0.18
Identities = 28/108 (25%), Positives = 47/108 (43%), Gaps = 9/108 (8%)
Query: 147 PSALTYSSSKSPAAQAGETTKAYQRPPI---PGTTAQPVTLMQLL------AVTVAVATP 197
P+A + +K AA+ T A RPP+ P T A+PV A VAT
Sbjct: 2701 PAAAKPAPAKPVAAKPVATKMATVRPPVAVKPATAAKPVAAKPAAVRPPAAAAAKPVATK 2760
Query: 198 TTLPRPSPSAASTTSIPRPQSVGHRSQEMDLWSTATYTSSQNRPRADP 245
+PRP + + T + + S+E+ ++ ++ + RA+P
Sbjct: 2761 PEVPRPQAAKPAATKPATTKPMVKMSREVQVFEITENSAKLHWERAEP 2808
>gi|240255542 alpha 3 type VI collagen isoform 2 precursor [Homo
sapiens]
Length = 1036
Score = 155 bits (392), Expect = 1e-37
Identities = 114/389 (29%), Positives = 198/389 (50%), Gaps = 22/389 (5%)
Query: 306 KIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTH 365
K D+ FL+DGS+++G F + +A V Q L+IG + V QY D F TH
Sbjct: 36 KRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTH 95
Query: 366 TNSRDLKTAIEKITQRGGLS-NVGRAISFVTKNFFSKANGNRS--GAPNVVVVMVDGWPT 422
R++ TA+ K+ G + G A+ FV N F+ + G R+ G P ++V++ G
Sbjct: 96 PTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSL 155
Query: 423 DKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWFGL 482
D++ + ++ + S I F I +GA + E + + F + V F + +Q L
Sbjct: 156 DEISQPAQELKRSSIMAFAIGNKGADQAELEEIA---FDSSLVFIPAEFRAAPLQGM--L 210
Query: 483 HKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEI 542
L PL + + T + +K DI F++DGS++VG NF V FV NL +I
Sbjct: 211 PGLLAPL-RTLSGTPEVHSNKR-----DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDI 264
Query: 543 SDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSG-GTSTGAAINFALEQLF 601
+ + R+G VQ++ EF + Y +K DIL ++++ G G +TG+A+++ F
Sbjct: 265 GNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHF 324
Query: 602 KKS-----KPNKRKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIAT 656
++ + + +L++L+T G+S D A A G++T+ +G + A + ELE IA
Sbjct: 325 TEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAF 384
Query: 657 HPARDHSFFVDEFDNLHQYVPRIIQNICT 685
+P+ + +D+F +L ++IQ + T
Sbjct: 385 NPSL--VYLMDDFSSLPALPQQLIQPLTT 411
Score = 147 bits (370), Expect = 4e-35
Identities = 106/363 (29%), Positives = 177/363 (48%), Gaps = 17/363 (4%)
Query: 306 KIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTH 365
K D+ FL+DGS ++GK F + + ++ +LDIG +G+VQ+ D P T F+L T+
Sbjct: 230 KRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTY 289
Query: 366 TNSRDLKTAIEKITQRGGLS-NVGRAISFVTKNFFSKANGNR--SGAPNVVVVMVDGWPT 422
D+ + ++ +GG N G A+S+V N F++A G+R P +++++ G
Sbjct: 290 QTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSE 349
Query: 423 DKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWFGL 482
D +A+ +GI F + GA++ K + + F V + F SL
Sbjct: 350 DSYLQAANALTRAGILTFCV---GASQANKAELEQIAFNPSLVYLMDDFSSLPALP---- 402
Query: 483 HKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEI 542
+ +QPL V + DI F+ DGS+++ G F V F+ + E +
Sbjct: 403 QQLIQPLTTYVSGGVEEVPLAQPESKRDILFLFDGSANL-VGQFPVVRDFLYKIIDELNV 461
Query: 543 SDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSG-GTSTGAAINFALEQLF 601
TRI QY+ + ++E FD++ SKP+ILN +KR+ +G + G A+++A +F
Sbjct: 462 KPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIF 521
Query: 602 KKSKPNK-----RKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIAT 656
KS ++ + ++L+ GRS D V PA GV+ + A ELE I
Sbjct: 522 VKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVL 581
Query: 657 HPA 659
PA
Sbjct: 582 SPA 584
Score = 122 bits (305), Expect = 1e-27
Identities = 129/504 (25%), Positives = 220/504 (43%), Gaps = 48/504 (9%)
Query: 217 QSVGHRSQEMDLWSTATYTSSQNRPRADPGIQRQDPSGAA---FQKPVGADVSLGEMDSW 273
+S G R ++ L + ++ R D SG FQ AD + E
Sbjct: 523 KSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAK-NADPAELEQIVL 581
Query: 274 KPGSVLLDEGLVPKEELSTQS---LEPVSLGDP---NCKIDLSFLIDGSTSIGKRRFRIQ 327
P +L E L +L Q L+ V G P + + D+ FL+DGS + + F +
Sbjct: 582 SPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGV-RSGFPLL 640
Query: 328 KQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTNSRDLKTAIEKITQRGG-LSN 386
K+ + V ++LD+G + VVQY D F L ++ N +D+ A+ ++T GG N
Sbjct: 641 KEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPN 700
Query: 387 VGRAISFVTKNFFSKANGNR--SGAPNVVVVMVDGWPTDKVEEASRLARESGINIFFITI 444
G A+ FV +N + G+R G P +++V+ D V S + + G I I
Sbjct: 701 TGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGI 760
Query: 445 EGAAENEKQYV-VEPNFANKAVCRTNGFYSLHVQSWFGLHKTLQPLVKRVCDTDRLACSK 503
A E Q + P+FA + + ++ L Q + +RV R S+
Sbjct: 761 GNADITEMQTISFIPDFA------------VAIPTFRQLGTVQQVISERVTQLTREELSR 808
Query: 504 T-----------CLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAV 552
D+ F+IDGS S G F+ V + L ++ TR+ +
Sbjct: 809 LQPVLQPLPSPGVGGKRDVVFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVI 867
Query: 553 QYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSG-GTSTGAAINFALEQLFKKSKPNK--- 608
Q++ + ++EF + +SSK ++ NA++R+ G + G A+ + +FK+ ++
Sbjct: 868 QFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEE 927
Query: 609 --RKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFV 666
+ ++LI+ G+S D+V PA+ GV + I A QEEL I+ P ++ F V
Sbjct: 928 GVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSP--EYVFSV 984
Query: 667 DEFDNLHQYVPRIIQNICTEFNSQ 690
F L +++ I T + Q
Sbjct: 985 STFRELPSLEQKLLTPITTLTSEQ 1008
Score = 88.6 bits (218), Expect = 2e-17
Identities = 50/156 (32%), Positives = 83/156 (53%), Gaps = 6/156 (3%)
Query: 506 LNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFGFD 565
+N DI F++DGSS++G NF + F+ + + EI ++ QY R EF F+
Sbjct: 34 VNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFN 93
Query: 566 KYSSKPDILNAIKRVGYWSGGT-STGAAINFALEQLFKKSKPNKR-----KLMILITDGR 619
+ +K +++ A++++ G TG+A++F LF S + KL++LIT G+
Sbjct: 94 THPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGK 153
Query: 620 SYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIA 655
S D++ PA ++ +AIG A Q ELE IA
Sbjct: 154 SLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIA 189
>gi|240255540 alpha 3 type VI collagen isoform 3 precursor [Homo
sapiens]
Length = 1237
Score = 155 bits (392), Expect = 1e-37
Identities = 114/389 (29%), Positives = 198/389 (50%), Gaps = 22/389 (5%)
Query: 306 KIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTH 365
K D+ FL+DGS+++G F + +A V Q L+IG + V QY D F TH
Sbjct: 237 KRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTH 296
Query: 366 TNSRDLKTAIEKITQRGGLS-NVGRAISFVTKNFFSKANGNRS--GAPNVVVVMVDGWPT 422
R++ TA+ K+ G + G A+ FV N F+ + G R+ G P ++V++ G
Sbjct: 297 PTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSL 356
Query: 423 DKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWFGL 482
D++ + ++ + S I F I +GA + E + + F + V F + +Q L
Sbjct: 357 DEISQPAQELKRSSIMAFAIGNKGADQAELEEIA---FDSSLVFIPAEFRAAPLQGM--L 411
Query: 483 HKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEI 542
L PL + + T + +K DI F++DGS++VG NF V FV NL +I
Sbjct: 412 PGLLAPL-RTLSGTPEVHSNKR-----DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDI 465
Query: 543 SDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSG-GTSTGAAINFALEQLF 601
+ + R+G VQ++ EF + Y +K DIL ++++ G G +TG+A+++ F
Sbjct: 466 GNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHF 525
Query: 602 KKS-----KPNKRKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIAT 656
++ + + +L++L+T G+S D A A G++T+ +G + A + ELE IA
Sbjct: 526 TEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAF 585
Query: 657 HPARDHSFFVDEFDNLHQYVPRIIQNICT 685
+P+ + +D+F +L ++IQ + T
Sbjct: 586 NPSL--VYLMDDFSSLPALPQQLIQPLTT 612
Score = 154 bits (390), Expect = 2e-37
Identities = 105/364 (28%), Positives = 181/364 (49%), Gaps = 25/364 (6%)
Query: 308 DLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTN 367
D+ FLIDGS + G F + L ++ + L IG +GVVQ+ D P T F+L T++
Sbjct: 36 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYST 95
Query: 368 SRDLKTAIEKITQRGG-LSNVGRAISFVTKNFFSKANGNR--SGAPNVVVVMVDGWPTDK 424
+ A++ + GG L+N+G A+ FV +N F++A G+R G P V+V++ G +D+
Sbjct: 96 KAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDE 155
Query: 425 VEEASRLARESGINIFFITIEGAAENEKQYVV-EPNFANKAVCRTNGFYSLHVQSWFGLH 483
+ +++ + F + + A+ E Q++ + N F +S+ L
Sbjct: 156 IRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLV---------FTVPEFRSFGDLQ 206
Query: 484 KTLQPLVKRVCDTDRLACSKTCL------NSADIGFVIDGSSSVGTGNFRTVLQFVTNLT 537
+ L P + V + T + N DI F++DGSS++G NF + F+ +
Sbjct: 207 EKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVI 266
Query: 538 KEFEISDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSGGT-STGAAINFA 596
+ EI ++ QY R EF F+ + +K +++ A++++ G TG+A++F
Sbjct: 267 QRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFV 326
Query: 597 LEQLFKKSKPNKR-----KLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEEL 651
LF S + KL++LIT G+S D++ PA ++ +AIG A Q EL
Sbjct: 327 RNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAEL 386
Query: 652 EVIA 655
E IA
Sbjct: 387 EEIA 390
Score = 147 bits (370), Expect = 4e-35
Identities = 106/363 (29%), Positives = 177/363 (48%), Gaps = 17/363 (4%)
Query: 306 KIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTH 365
K D+ FL+DGS ++GK F + + ++ +LDIG +G+VQ+ D P T F+L T+
Sbjct: 431 KRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTY 490
Query: 366 TNSRDLKTAIEKITQRGGLS-NVGRAISFVTKNFFSKANGNR--SGAPNVVVVMVDGWPT 422
D+ + ++ +GG N G A+S+V N F++A G+R P +++++ G
Sbjct: 491 QTKSDILGHLRQLQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSE 550
Query: 423 DKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWFGL 482
D +A+ +GI F + GA++ K + + F V + F SL
Sbjct: 551 DSYLQAANALTRAGILTFCV---GASQANKAELEQIAFNPSLVYLMDDFSSLPALP---- 603
Query: 483 HKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEI 542
+ +QPL V + DI F+ DGS+++ G F V F+ + E +
Sbjct: 604 QQLIQPLTTYVSGGVEEVPLAQPESKRDILFLFDGSANL-VGQFPVVRDFLYKIIDELNV 662
Query: 543 SDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSG-GTSTGAAINFALEQLF 601
TRI QY+ + ++E FD++ SKP+ILN +KR+ +G + G A+++A +F
Sbjct: 663 KPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIF 722
Query: 602 KKSKPNK-----RKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIAT 656
KS ++ + ++L+ GRS D V PA GV+ + A ELE I
Sbjct: 723 VKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVL 782
Query: 657 HPA 659
PA
Sbjct: 783 SPA 785
Score = 122 bits (305), Expect = 1e-27
Identities = 129/504 (25%), Positives = 220/504 (43%), Gaps = 48/504 (9%)
Query: 217 QSVGHRSQEMDLWSTATYTSSQNRPRADPGIQRQDPSGAA---FQKPVGADVSLGEMDSW 273
+S G R ++ L + ++ R D SG FQ AD + E
Sbjct: 724 KSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAK-NADPAELEQIVL 782
Query: 274 KPGSVLLDEGLVPKEELSTQS---LEPVSLGDP---NCKIDLSFLIDGSTSIGKRRFRIQ 327
P +L E L +L Q L+ V G P + + D+ FL+DGS + + F +
Sbjct: 783 SPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGV-RSGFPLL 841
Query: 328 KQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTNSRDLKTAIEKITQRGG-LSN 386
K+ + V ++LD+G + VVQY D F L ++ N +D+ A+ ++T GG N
Sbjct: 842 KEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPN 901
Query: 387 VGRAISFVTKNFFSKANGNR--SGAPNVVVVMVDGWPTDKVEEASRLARESGINIFFITI 444
G A+ FV +N + G+R G P +++V+ D V S + + G I I
Sbjct: 902 TGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGI 961
Query: 445 EGAAENEKQYV-VEPNFANKAVCRTNGFYSLHVQSWFGLHKTLQPLVKRVCDTDRLACSK 503
A E Q + P+FA + + ++ L Q + +RV R S+
Sbjct: 962 GNADITEMQTISFIPDFA------------VAIPTFRQLGTVQQVISERVTQLTREELSR 1009
Query: 504 T-----------CLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAV 552
D+ F+IDGS S G F+ V + L ++ TR+ +
Sbjct: 1010 LQPVLQPLPSPGVGGKRDVVFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVI 1068
Query: 553 QYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSG-GTSTGAAINFALEQLFKKSKPNK--- 608
Q++ + ++EF + +SSK ++ NA++R+ G + G A+ + +FK+ ++
Sbjct: 1069 QFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEE 1128
Query: 609 --RKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFV 666
+ ++LI+ G+S D+V PA+ GV + I A QEEL I+ P ++ F V
Sbjct: 1129 GVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSP--EYVFSV 1185
Query: 667 DEFDNLHQYVPRIIQNICTEFNSQ 690
F L +++ I T + Q
Sbjct: 1186 STFRELPSLEQKLLTPITTLTSEQ 1209
Score = 96.7 bits (239), Expect = 7e-20
Identities = 53/156 (33%), Positives = 92/156 (58%), Gaps = 6/156 (3%)
Query: 507 NSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFGFDK 566
+SADI F+IDGS++ G+ NF +L F+ NL ++ I R+G VQ++ E R F D
Sbjct: 33 DSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDT 92
Query: 567 YSSKPDILNAIKRVGYWSGG-TSTGAAINFALEQLFKKSKPNK-----RKLMILITDGRS 620
YS+K +L A+K +G+ G + G A++F +E F ++ ++ ++++LI+ G S
Sbjct: 93 YSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPS 152
Query: 621 YDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIAT 656
D++R +A V ++ +G A++ EL+ IAT
Sbjct: 153 SDEIRYGVVALKQASVFSFGLGAQAASRAELQHIAT 188
>gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo
sapiens]
Length = 2570
Score = 140 bits (354), Expect = 3e-33
Identities = 108/407 (26%), Positives = 192/407 (47%), Gaps = 15/407 (3%)
Query: 287 KEELSTQS--LEPVSLGDPNCKIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAG 344
+EELS L+P+ K D+ FLIDGS S G F+ + L+ + LD+G
Sbjct: 603 REELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDT 661
Query: 345 PLMGVVQYGDNPATHFNLKTHTNSRDLKTAIEKITQRGGLS-NVGRAISFVTKNFFSKAN 403
+ V+Q+ D+P F L H++ +++ A++++ +GG NVG A+ +V++N F +
Sbjct: 662 TRVAVIQFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPL 721
Query: 404 GNR--SGAPNVVVVMVDGWPTDKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFA 461
G+R G P +V++ G D+V++ + ++ G+ F I E + + P +
Sbjct: 722 GSRIEEGVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTIARNADQEELVKISLSPEYV 781
Query: 462 NKAVCRTNGFYSLHVQSWFGLHKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSV 521
+V SL + + ++++ + R ++ADI F+ID S V
Sbjct: 782 F-SVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGV 840
Query: 522 GTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVG 581
F + FV+ + + I + R+G VQ++ + EF Y S+ +L+AI+R+
Sbjct: 841 RPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLR 900
Query: 582 YWSGG-TSTGAAINFALEQLFKKSKPNK-----RKLMILITDGRSYDDVRIPAMAAHLKG 635
G +TG A+ F LF KS ++ + ++L+ G+S DDV A G
Sbjct: 901 LRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQVIRSSG 960
Query: 636 VITYAIGVAWAAQEELEVIATHPARDHSFFVDEFDNLHQYVPRIIQN 682
+++ +G + EL+ I P F V EF L RI+ +
Sbjct: 961 IVSLGVGDRNIDRTELQTITNDPRL--VFTVREFRELPNIEERIMNS 1005
Score = 138 bits (348), Expect = 2e-32
Identities = 107/364 (29%), Positives = 175/364 (48%), Gaps = 25/364 (6%)
Query: 306 KIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTH 365
K D+ FL+DGS+++G F + +A V Q L+IG + V QY D F TH
Sbjct: 36 KRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTH 95
Query: 366 TNSRDLKTAIEKITQRGGLS-NVGRAISFVTKNFFSKANGNRS--GAPNVVVVMVDGWPT 422
R++ TA+ K+ G + G A+ FV N F+ + G R+ G P ++V++ G
Sbjct: 96 PTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSL 155
Query: 423 DKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWF-G 481
D++ + ++ + S I F I +GA + E + + F + V F + +Q G
Sbjct: 156 DEISQPAQELKRSSIMAFAIGNKGADQAELEEIA---FDSSLVFIPAEFRAAPLQGMLPG 212
Query: 482 LHKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFE 541
L L+ L ++ R DI F+ DGS+++ G F V F+ + E
Sbjct: 213 LLAPLRTLSGTPEESKR-----------DILFLFDGSANL-VGQFPVVRDFLYKIIDELN 260
Query: 542 ISDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSG-GTSTGAAINFALEQL 600
+ TRI QY+ + ++E FD++ SKP+ILN +KR+ +G + G A+++A +
Sbjct: 261 VKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYI 320
Query: 601 FKKSKPNK-----RKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIA 655
F KS ++ + ++L+ GRS D V PA GV+ + A ELE I
Sbjct: 321 FVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIV 380
Query: 656 THPA 659
PA
Sbjct: 381 LSPA 384
Score = 122 bits (305), Expect = 1e-27
Identities = 129/504 (25%), Positives = 220/504 (43%), Gaps = 48/504 (9%)
Query: 217 QSVGHRSQEMDLWSTATYTSSQNRPRADPGIQRQDPSGAA---FQKPVGADVSLGEMDSW 273
+S G R ++ L + ++ R D SG FQ AD + E
Sbjct: 323 KSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAK-NADPAELEQIVL 381
Query: 274 KPGSVLLDEGLVPKEELSTQS---LEPVSLGDP---NCKIDLSFLIDGSTSIGKRRFRIQ 327
P +L E L +L Q L+ V G P + + D+ FL+DGS + + F +
Sbjct: 382 SPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGV-RSGFPLL 440
Query: 328 KQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTNSRDLKTAIEKITQRGG-LSN 386
K+ + V ++LD+G + VVQY D F L ++ N +D+ A+ ++T GG N
Sbjct: 441 KEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPN 500
Query: 387 VGRAISFVTKNFFSKANGNR--SGAPNVVVVMVDGWPTDKVEEASRLARESGINIFFITI 444
G A+ FV +N + G+R G P +++V+ D V S + + G I I
Sbjct: 501 TGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGI 560
Query: 445 EGAAENEKQYV-VEPNFANKAVCRTNGFYSLHVQSWFGLHKTLQPLVKRVCDTDRLACSK 503
A E Q + P+FA + + ++ L Q + +RV R S+
Sbjct: 561 GNADITEMQTISFIPDFA------------VAIPTFRQLGTVQQVISERVTQLTREELSR 608
Query: 504 T-----------CLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAV 552
D+ F+IDGS S G F+ V + L ++ TR+ +
Sbjct: 609 LQPVLQPLPSPGVGGKRDVVFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVI 667
Query: 553 QYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSG-GTSTGAAINFALEQLFKKSKPNK--- 608
Q++ + ++EF + +SSK ++ NA++R+ G + G A+ + +FK+ ++
Sbjct: 668 QFSDDPKVEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEE 727
Query: 609 --RKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFV 666
+ ++LI+ G+S D+V PA+ GV + I A QEEL I+ P ++ F V
Sbjct: 728 GVPQFLVLISSGKSDDEVDDPAVELKQFGVAPFTI-ARNADQEELVKISLSP--EYVFSV 784
Query: 667 DEFDNLHQYVPRIIQNICTEFNSQ 690
F L +++ I T + Q
Sbjct: 785 STFRELPSLEQKLLTPITTLTSEQ 808
Score = 121 bits (303), Expect = 2e-27
Identities = 103/390 (26%), Positives = 180/390 (46%), Gaps = 23/390 (5%)
Query: 308 DLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTN 367
D+ FLID S + F + ++ + + L+IGP+ +GVVQ+ ++ F LKT+ +
Sbjct: 829 DIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRS 888
Query: 368 SRDLKTAIEKITQRGGLS-NVGRAISFVTKNFFSKANGNR--SGAPNVVVVMVDGWPTDK 424
+ AI ++ RGG N G+A+ FV +N F K+ G+R G P +V+++ G D
Sbjct: 889 QAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDD 948
Query: 425 VEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSL-----HVQSW 479
V +++ R SGI + E Q + + V F L + +
Sbjct: 949 VSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDP---RLVFTVREFRELPNIEERIMNS 1005
Query: 480 FGLHKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKE 539
FG P V D S+ ADI F++DGS + +F+ VL+FV+ +
Sbjct: 1006 FG-PSAATPAPPGV---DTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDT 1061
Query: 540 FEISDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSG---GTSTG---AAI 593
++G VQY + EF +S+K I++AI +V Y G T G +
Sbjct: 1062 VYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRV 1121
Query: 594 NFALEQLFKKSKPNKRKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEV 653
N + + + ++ +IT G+S +D + ++A +GV +A+GV EE+
Sbjct: 1122 NHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGK 1181
Query: 654 IATHPARDHSFFVDEFDNLHQYVPRIIQNI 683
IA++ A +F V L + ++++ +
Sbjct: 1182 IASNSAT--AFRVGNVQELSELSEQVLETL 1209
Score = 88.6 bits (218), Expect = 2e-17
Identities = 50/156 (32%), Positives = 83/156 (53%), Gaps = 6/156 (3%)
Query: 506 LNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFGFD 565
+N DI F++DGSS++G NF + F+ + + EI ++ QY R EF F+
Sbjct: 34 VNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFN 93
Query: 566 KYSSKPDILNAIKRVGYWSGGT-STGAAINFALEQLFKKSKPNKR-----KLMILITDGR 619
+ +K +++ A++++ G TG+A++F LF S + KL++LIT G+
Sbjct: 94 THPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGK 153
Query: 620 SYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIA 655
S D++ PA ++ +AIG A Q ELE IA
Sbjct: 154 SLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIA 189
Score = 67.0 bits (162), Expect = 6e-11
Identities = 74/332 (22%), Positives = 134/332 (40%), Gaps = 25/332 (7%)
Query: 306 KIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTH 365
K D+ FL+DGS + + F+ + ++++ + +G+VQY +P F LK
Sbjct: 1030 KADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDF 1089
Query: 366 TNSRDLKTAIEKITQRGGL-SNVGRAISFVTKNFFSKANGNR--SGAPNVVVVMVDGWPT 422
+ R + AI K+ +GG +N + + N F G+R P + V+ G
Sbjct: 1090 STKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGGKSV 1149
Query: 423 DKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWFGL 482
+ ++ S + G+ +F + + E + + V L Q L
Sbjct: 1150 EDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSELSEQVLETL 1209
Query: 483 HKTL-QPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSS----VGTGNFRTVLQFVTN-L 536
H + + L V D +K C +GF DGS V F + + + N +
Sbjct: 1210 HDAMHETLCPGVTD-----AAKACNLDVILGF--DGSRDQNVFVAQKGFESKVDAILNRI 1262
Query: 537 TKEFEIS-----DTDTRIGAVQYTYEQRLE-FGFDKYSSKPDILNAIKRVGYWSGGTSTG 590
++ +S R+ V T +E F FD+Y +P++L + + T
Sbjct: 1263 SQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEY--QPEMLEKFRNMRSQHPYVLTE 1320
Query: 591 AAINFALEQLFKKSKPNKRKLMILITDGRSYD 622
+ L + F++S P+ K++I TDG D
Sbjct: 1321 DTLKVYLNK-FRQSSPDSVKVVIHFTDGADGD 1351
Score = 42.0 bits (97), Expect = 0.002
Identities = 44/176 (25%), Positives = 80/176 (45%), Gaps = 25/176 (14%)
Query: 307 IDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPL------MGVVQYG-----DN 355
ID++F++D + + +F K+ +A + + LD+ P + VVQ+ DN
Sbjct: 2011 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDN 2070
Query: 356 PA-----THFNLKTHTNSRDLKTAIEK-ITQRGGLSNVGRAISFVTKNFFSKANGNRSGA 409
+ F+L + + L + + +TQ G +G AI + +N F A R
Sbjct: 2071 ASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRD-- 2128
Query: 410 PNVVVVMVDG-WPTDKVEEASRLARESGINIFFITIEGAAE--NEKQ---YVVEPN 459
+VV+M+ G P ++EEA R+ ++ +F + G N K+ + EPN
Sbjct: 2129 LKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPN 2184
Score = 35.4 bits (80), Expect = 0.18
Identities = 28/108 (25%), Positives = 47/108 (43%), Gaps = 9/108 (8%)
Query: 147 PSALTYSSSKSPAAQAGETTKAYQRPPI---PGTTAQPVTLMQLL------AVTVAVATP 197
P+A + +K AA+ T A RPP+ P T A+PV A VAT
Sbjct: 2300 PAAAKPAPAKPVAAKPVATKMATVRPPVAVKPATAAKPVAAKPAAVRPPAAAAAKPVATK 2359
Query: 198 TTLPRPSPSAASTTSIPRPQSVGHRSQEMDLWSTATYTSSQNRPRADP 245
+PRP + + T + + S+E+ ++ ++ + RA+P
Sbjct: 2360 PEVPRPQAAKPAATKPATTKPMVKMSREVQVFEITENSAKLHWERAEP 2407
>gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]
Length = 1796
Score = 132 bits (333), Expect = 8e-31
Identities = 76/206 (36%), Positives = 112/206 (54%), Gaps = 12/206 (5%)
Query: 490 VKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRI 549
VK VC T +A DI ++DGS S+G NFR V F+ NL F++ TRI
Sbjct: 147 VKFVCQTPAIA---------DIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRI 197
Query: 550 GAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQLFKK---SKP 606
G QY+ + R+E+ + +S+K +++ A++ + Y G T TG A+N+ E FK S+
Sbjct: 198 GLAQYSGDPRIEWHLNAFSTKDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSRT 257
Query: 607 NKRKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFV 666
K+ ILITDG+S DD+ P+ GV +AIGV A EL+ IA+ P H + V
Sbjct: 258 GVSKIGILITDGKSQDDIIPPSRNLRESGVELFAIGVKNADVNELQEIASEPDSTHVYNV 317
Query: 667 DEFDNLHQYVPRIIQNICTEFNSQPR 692
EFD +H V + + +C+ Q R
Sbjct: 318 AEFDLMHTVVESLTRTLCSRVEEQDR 343
Score = 118 bits (296), Expect = 2e-26
Identities = 67/180 (37%), Positives = 99/180 (55%), Gaps = 4/180 (2%)
Query: 509 ADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTD-TRIGAVQYTYEQRLEFGFDKY 567
AD+ F++DGS S+G NF ++ F+ + TD T++ VQ+T + R EF + Y
Sbjct: 1031 ADLVFMVDGSWSIGDENFNKIISFLYSTVGALNKIGTDGTQVAMVQFTDDPRTEFKLNAY 1090
Query: 568 SSKPDILNAIKRVGYWSGGTSTGAAINFALEQLFKKSKPNKR---KLMILITDGRSYDDV 624
+K +L+AIK + Y G T TG AI + + LF +R K++++ITDGRS DDV
Sbjct: 1091 KTKETLLDAIKHISYKGGNTKTGKAIKYVRDTLFTAESGTRRGIPKVIVVITDGRSQDDV 1150
Query: 625 RIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFVDEFDNLHQYVPRIIQNIC 684
+ L G +AIGVA A EL I + P+ H FFVD+FD + +I +C
Sbjct: 1151 NKISREMQLDGYSIFAIGVADADYSELVSIGSKPSARHVFFVDDFDAFKKIEDELITFVC 1210
Score = 93.2 bits (230), Expect = 7e-19
Identities = 64/197 (32%), Positives = 95/197 (48%), Gaps = 10/197 (5%)
Query: 306 KIDLSFLIDGSTSIGKRRF-RIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKT 364
K DL F++DGS SIG F +I L + V IG G + +VQ+ D+P T F L
Sbjct: 1030 KADLVFMVDGSWSIGDENFNKIISFLYSTVGALNKIGTDGTQVAMVQFTDDPRTEFKLNA 1089
Query: 365 HTNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSGAPNVVVVMVDGWPTDK 424
+ L AI+ I+ +GG + G+AI +V F+ +G R G P V+VV+ DG D
Sbjct: 1090 YKTKETLLDAIKHISYKGGNTKTGKAIKYVRDTLFTAESGTRRGIPKVIVVITDGRSQDD 1149
Query: 425 VEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWFGLHK 484
V + SR + G +IF I G A+ + +V + +K R + V + K
Sbjct: 1150 VNKISREMQLDGYSIFAI---GVADADYSELV--SIGSKPSAR----HVFFVDDFDAFKK 1200
Query: 485 TLQPLVKRVCDTDRLAC 501
L+ VC+T C
Sbjct: 1201 IEDELITFVCETASATC 1217
Score = 90.9 bits (224), Expect = 4e-18
Identities = 46/153 (30%), Positives = 84/153 (54%), Gaps = 1/153 (0%)
Query: 308 DLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTN 367
D+ L+DGS SIG+ FR+ + L ++ A D+G +G+ QY +P ++L +
Sbjct: 158 DIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLAQYSGDPRIEWHLNAFST 217
Query: 368 SRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSGAPNVVVVMVDGWPTDKVEE 427
++ A+ + +GG + G A++++ +N F G+R+G + +++ DG D +
Sbjct: 218 KDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSRTGVSKIGILITDGKSQDDIIP 277
Query: 428 ASRLARESGINIFFITIEGAAENEKQYVV-EPN 459
SR RESG+ +F I ++ A NE Q + EP+
Sbjct: 278 PSRNLRESGVELFAIGVKNADVNELQEIASEPD 310
>gi|93141047 collagen, type XII, alpha 1 long isoform precursor
[Homo sapiens]
Length = 3063
Score = 132 bits (331), Expect = 1e-30
Identities = 73/207 (35%), Positives = 119/207 (57%), Gaps = 5/207 (2%)
Query: 487 QPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTD 546
+P+ K+ T+ CS + D+ F++DGS SVG NF+ +L F+ L F+I +
Sbjct: 119 KPVEKKPGKTEIQKCSVSAWT--DLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEK 176
Query: 547 TRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQLFKKS-- 604
TR+G VQY+ + R EF ++Y + ++L AIK++ Y G T TG AI++ ++ F +S
Sbjct: 177 TRVGVVQYSSDTRTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAG 236
Query: 605 -KPNKRKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHS 663
+ K+ I+ITDG+S D+V IPA GV +++G+ A +EL+ IA+ P+ +H
Sbjct: 237 ARVGFPKVAIIITDGKSQDEVEIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHV 296
Query: 664 FFVDEFDNLHQYVPRIIQNICTEFNSQ 690
F V FD + II +C+ + Q
Sbjct: 297 FNVANFDAIVDIQNEIISQVCSGVDEQ 323
Score = 131 bits (330), Expect = 2e-30
Identities = 76/196 (38%), Positives = 108/196 (55%), Gaps = 3/196 (1%)
Query: 498 RLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYE 557
++ CS+ ADI F++DGS S+G NF V F+ L K FEIS +I VQY+ +
Sbjct: 428 QVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRD 487
Query: 558 QRLEFGFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQLF---KKSKPNKRKLMIL 614
EF K++ DI+ AI Y G T+TG A+ + E++F K S+ N K+MIL
Sbjct: 488 PHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMIL 547
Query: 615 ITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFVDEFDNLHQ 674
ITDG+S D R PA+ V +A+GV A + ELE IA+ PA H F V++FD +
Sbjct: 548 ITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQR 607
Query: 675 YVPRIIQNICTEFNSQ 690
+ Q+IC +
Sbjct: 608 ISFELTQSICLRIEQE 623
Score = 125 bits (314), Expect = 1e-28
Identities = 69/191 (36%), Positives = 109/191 (57%), Gaps = 5/191 (2%)
Query: 499 LACSKTCLN--SADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTY 556
L+ CL ADI ++DGS S+G NFRTV F++ + + F+I +I QY+
Sbjct: 1186 LSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSG 1245
Query: 557 EQRLEFGFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQLFKKS---KPNKRKLMI 613
+ R E+ + + K +L A+ + Y G T TG A+NF +Q F+ +P RK+ +
Sbjct: 1246 DPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGV 1305
Query: 614 LITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFVDEFDNLH 673
LITDG+S DDV P+ +GV +AIG+ A + EL++IAT P H++ V +F++L
Sbjct: 1306 LITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLS 1365
Query: 674 QYVPRIIQNIC 684
+ V + N+C
Sbjct: 1366 RIVDDLTINLC 1376
Score = 108 bits (269), Expect = 2e-23
Identities = 61/180 (33%), Positives = 97/180 (53%), Gaps = 4/180 (2%)
Query: 509 ADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEF-EISDTDTRIGAVQYTYEQRLEFGFDKY 567
ADI F+ D S S+G NF V++F+ N F EIS ++ VQY+ E + EF + Y
Sbjct: 2322 ADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTY 2381
Query: 568 SSKPDILNAIKRVGYWSGGTSTGAAINFALEQLF---KKSKPNKRKLMILITDGRSYDDV 624
+ K L A++ + Y G T TG A+ F E++ + N K+++++TDGRS D+V
Sbjct: 2382 NDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEV 2441
Query: 625 RIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFVDEFDNLHQYVPRIIQNIC 684
+ A+ G + +GVA EL IA+ P+ H F VD+F++ + +I +C
Sbjct: 2442 KKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVC 2501
Score = 103 bits (257), Expect = 5e-22
Identities = 57/153 (37%), Positives = 86/153 (56%), Gaps = 1/153 (0%)
Query: 308 DLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTN 367
DL FL+DGS S+G+ F+ +A + A DIG +GVVQY + T FNL +
Sbjct: 140 DLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYYQ 199
Query: 368 SRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSGAPNVVVVMVDGWPTDKVEE 427
+L AI+KI +GG + G AI ++ KN F+++ G R G P V +++ DG D+VE
Sbjct: 200 RDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARVGFPKVAIIITDGKSQDEVEI 259
Query: 428 ASRLARESGINIFFITIEGA-AENEKQYVVEPN 459
+R R G+ +F + I+ A A+ KQ P+
Sbjct: 260 PARELRNVGVEVFSLGIKAADAKELKQIASTPS 292
Score = 95.5 bits (236), Expect = 1e-19
Identities = 49/153 (32%), Positives = 82/153 (53%)
Query: 306 KIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTH 365
K D+ FL+DGS SIG F + L + ++ +I P + +VQY +P T F LK
Sbjct: 438 KADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKF 497
Query: 366 TNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSGAPNVVVVMVDGWPTDKV 425
T D+ AI RGG +N G+A+++V + F + G+RS P V++++ DG +D
Sbjct: 498 TKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAF 557
Query: 426 EEASRLARESGINIFFITIEGAAENEKQYVVEP 458
+ + R S + IF + ++ A +E + + P
Sbjct: 558 RDPAIKLRNSDVEIFAVGVKDAVRSELEAIASP 590
Score = 91.7 bits (226), Expect = 2e-18
Identities = 78/314 (24%), Positives = 135/314 (42%), Gaps = 40/314 (12%)
Query: 186 QLLAVTVAVATPTTLPRPSPSAASTTSIPRPQSVGHRSQEMDLWSTAT-YTSSQNRPRAD 244
Q++A T T L R P ++ +G +TA+ + S +N +D
Sbjct: 1038 QMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSD 1097
Query: 245 PGIQR----QDPSGAAFQ------KPVGADVSLGEM-----------DSWKPGSV----- 278
P + +P+ + P G D LGE+ + + G+
Sbjct: 1098 PTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNV 1157
Query: 279 --LLDEG----LVPKE--ELSTQSLEPVSLGDPNC----KIDLSFLIDGSTSIGKRRFRI 326
+ D G LV +E LS ++ P+ C + D+ L+DGS SIG+ FR
Sbjct: 1158 FGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRT 1217
Query: 327 QKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTNSRDLKTAIEKITQRGGLSN 386
+ ++ + + DIGP + + QY +P T + L H + + L A+ + +GG +
Sbjct: 1218 VRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTL 1277
Query: 387 VGRAISFVTKNFFSKANGNRSGAPNVVVVMVDGWPTDKVEEASRLARESGINIFFITIEG 446
G A++F+ + F G R A + V++ DG D VE S+ ++ G+ +F I I+
Sbjct: 1278 TGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKN 1337
Query: 447 AAENE-KQYVVEPN 459
A E E K +P+
Sbjct: 1338 ADEVELKMIATDPD 1351
Score = 87.4 bits (215), Expect = 4e-17
Identities = 64/226 (28%), Positives = 108/226 (47%), Gaps = 11/226 (4%)
Query: 306 KIDLSFLIDGSTSIGKRRF-RIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKT 364
K D+ FL D S SIG F ++ K + V +I PAG + VQY D + F L T
Sbjct: 2321 KADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNT 2380
Query: 365 HTNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSGAPNVVVVMVDGWPTDK 424
+ + A++ I RGG + G+A++F+ + + +G R P V+VV+ DG D+
Sbjct: 2381 YNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDE 2440
Query: 425 VEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWFGLHK 484
V++A+ + ++SG ++F + + NE N A+K R + V + K
Sbjct: 2441 VKKAALVIQQSGFSVFVVGVADVDYNEL-----ANIASKPSER----HVFIVDDFESFEK 2491
Query: 485 TLQPLVKRVCDTDRLACSKTCLNS-ADIGFVIDGSSSVGTGNFRTV 529
L+ VC+T +C L+ GF + + ++ NF +V
Sbjct: 2492 IEDNLITFVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASV 2537
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 127 bits (319), Expect = 3e-29
Identities = 75/199 (37%), Positives = 110/199 (55%), Gaps = 6/199 (3%)
Query: 497 DRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFE--ISDTDTRIGAVQY 554
+R+ C++ L +ADI F++DGSSS+G NFR V F+ L F S R VQY
Sbjct: 27 ERVTCTR--LYAADIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQY 84
Query: 555 TYEQRLEFGFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQLF--KKSKPNKRKLM 612
+ + R EFG D S D++ AI+ + Y G T TGAAI + +F + ++P K+
Sbjct: 85 SDDPRTEFGLDALGSGGDVIRAIRELSYKGGNTRTGAAILHVADHVFLPQLARPGVPKVC 144
Query: 613 ILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFVDEFDNL 672
ILITDG+S D V A +GV +A+G+ A EEL+ +A+ P D FFV++F L
Sbjct: 145 ILITDGKSQDLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFSIL 204
Query: 673 HQYVPRIIQNICTEFNSQP 691
+P + + +CT P
Sbjct: 205 RTLLPLVSRRVCTTAGGVP 223
Score = 79.7 bits (195), Expect = 8e-15
Identities = 62/195 (31%), Positives = 96/195 (49%), Gaps = 20/195 (10%)
Query: 308 DLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGV----VQYGDNPATHFNLK 363
D+ FL+DGS+SIG+ FR + L + L A GV VQY D+P T F L
Sbjct: 38 DIVFLLDGSSSIGRSNFREVRSFLEGLV--LPFSGAASAQGVRFATVQYSDDPRTEFGLD 95
Query: 364 THTNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSGAPNVVVVMVDGWPTD 423
+ D+ AI +++ +GG + G AI V + F R G P V +++ DG D
Sbjct: 96 ALGSGGDVIRAIRELSYKGGNTRTGAAILHVADHVFLPQLA-RPGVPKVCILITDGKSQD 154
Query: 424 KVEEASRLARESGINIFFITIEGAAENE-KQYVVEPNFANKAVCRTNGFYSLHVQSWFGL 482
V+ A++ + G+ +F + I+ A E K+ +P T+ F+ + F +
Sbjct: 155 LVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQP---------TSDFF--FFVNDFSI 203
Query: 483 HKTLQPLV-KRVCDT 496
+TL PLV +RVC T
Sbjct: 204 LRTLLPLVSRRVCTT 218
Score = 43.1 bits (100), Expect = 9e-04
Identities = 38/152 (25%), Positives = 66/152 (43%), Gaps = 7/152 (4%)
Query: 548 RIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWS-GGTSTGAAINFALEQLFKKSKP 606
++G + Y++ F + IL I+ + Y G + G A+ A + P
Sbjct: 1092 QVGLLSYSHRPSPLFPLNGSHDLGIILQRIRDMPYMDPSGNNLGTAVVTAHRYMLAPDAP 1151
Query: 607 NKRK----LMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDH 662
+R+ +M+L+ D D+ P A G+ +G+A A E+L +A
Sbjct: 1152 GRRQHVPGVMVLLVDEPLRGDIFSPIREAQASGLNVVMLGMAGADPEQLRRLAPGMDSVQ 1211
Query: 663 SFF-VDEFDNLHQYVPRIIQNIC-TEFNSQPR 692
+FF VD+ +L Q V + +C F +QPR
Sbjct: 1212 TFFAVDDGPSLDQAVSGLATALCQASFTTQPR 1243
Score = 42.7 bits (99), Expect = 0.001
Identities = 59/265 (22%), Positives = 107/265 (40%), Gaps = 33/265 (12%)
Query: 203 PSPSAASTTSIPRPQSVGHRSQEMDL------WSTATYTSSQN---RPRADPGIQ----- 248
PS + T PR S+ R + + W+ + SS RP PG +
Sbjct: 944 PSAEVTARTESPRVPSIELRVVDTSIDSVTLAWTPVSRASSYILSWRPLRGPGQEVPGSP 1003
Query: 249 RQDPSGAAFQKPVGADVSLGEMDSWKPGSVLLDEGLVPKEELSTQSLEPVSLGDPNCKID 308
+ P ++ Q+ G + + + S P +LD P+ ++ + P L D
Sbjct: 1004 QTLPGISSSQRVTGLEPGVSYIFSLTP---VLDGVRGPEASVTQTPVCPRGLADV----- 1055
Query: 309 LSFLIDGSTSIGKRRFRIQKQLLADVAQALD-IGPAGPLMGVVQYGDNPATHFNLKTHTN 367
+ +T R +++L + AL +GP +G++ Y P+ F L
Sbjct: 1056 --VFLPHATQDNAHRAEATRRVLERLVLALGPLGPQAVQVGLLSYSHRPSPLFPLN---G 1110
Query: 368 SRDLKTAIEKITQRGGL----SNVGRAISFVTKNFFSK-ANGNRSGAPNVVVVMVDGWPT 422
S DL +++I + +N+G A+ + + A G R P V+V++VD
Sbjct: 1111 SHDLGIILQRIRDMPYMDPSGNNLGTAVVTAHRYMLAPDAPGRRQHVPGVMVLLVDEPLR 1170
Query: 423 DKVEEASRLARESGINIFFITIEGA 447
+ R A+ SG+N+ + + GA
Sbjct: 1171 GDIFSPIREAQASGLNVVMLGMAGA 1195
>gi|93141049 collagen, type XII, alpha 1 short isoform precursor
[Homo sapiens]
Length = 1899
Score = 124 bits (312), Expect = 2e-28
Identities = 66/179 (36%), Positives = 105/179 (58%), Gaps = 3/179 (1%)
Query: 509 ADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFGFDKYS 568
ADI ++DGS S+G NFRTV F++ + + F+I +I QY+ + R E+ + +
Sbjct: 34 ADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHR 93
Query: 569 SKPDILNAIKRVGYWSGGTSTGAAINFALEQLFKKS---KPNKRKLMILITDGRSYDDVR 625
K +L A+ + Y G T TG A+NF +Q F+ +P RK+ +LITDG+S DDV
Sbjct: 94 DKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVE 153
Query: 626 IPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFVDEFDNLHQYVPRIIQNIC 684
P+ +GV +AIG+ A + EL++IAT P H++ V +F++L + V + N+C
Sbjct: 154 APSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLC 212
Score = 108 bits (269), Expect = 2e-23
Identities = 61/180 (33%), Positives = 97/180 (53%), Gaps = 4/180 (2%)
Query: 509 ADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEF-EISDTDTRIGAVQYTYEQRLEFGFDKY 567
ADI F+ D S S+G NF V++F+ N F EIS ++ VQY+ E + EF + Y
Sbjct: 1158 ADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTY 1217
Query: 568 SSKPDILNAIKRVGYWSGGTSTGAAINFALEQLF---KKSKPNKRKLMILITDGRSYDDV 624
+ K L A++ + Y G T TG A+ F E++ + N K+++++TDGRS D+V
Sbjct: 1218 NDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEV 1277
Query: 625 RIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFVDEFDNLHQYVPRIIQNIC 684
+ A+ G + +GVA EL IA+ P+ H F VD+F++ + +I +C
Sbjct: 1278 KKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVC 1337
Score = 90.1 bits (222), Expect = 6e-18
Identities = 47/153 (30%), Positives = 80/153 (52%), Gaps = 1/153 (0%)
Query: 308 DLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTN 367
D+ L+DGS SIG+ FR + ++ + + DIGP + + QY +P T + L H +
Sbjct: 35 DIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRD 94
Query: 368 SRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSGAPNVVVVMVDGWPTDKVEE 427
+ L A+ + +GG + G A++F+ + F G R A + V++ DG D VE
Sbjct: 95 KKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEA 154
Query: 428 ASRLARESGINIFFITIEGAAENE-KQYVVEPN 459
S+ ++ G+ +F I I+ A E E K +P+
Sbjct: 155 PSKKLKDEGVELFAIGIKNADEVELKMIATDPD 187
Score = 87.4 bits (215), Expect = 4e-17
Identities = 64/226 (28%), Positives = 108/226 (47%), Gaps = 11/226 (4%)
Query: 306 KIDLSFLIDGSTSIGKRRF-RIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKT 364
K D+ FL D S SIG F ++ K + V +I PAG + VQY D + F L T
Sbjct: 1157 KADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNT 1216
Query: 365 HTNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSGAPNVVVVMVDGWPTDK 424
+ + A++ I RGG + G+A++F+ + + +G R P V+VV+ DG D+
Sbjct: 1217 YNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDE 1276
Query: 425 VEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWFGLHK 484
V++A+ + ++SG ++F + + NE N A+K R + V + K
Sbjct: 1277 VKKAALVIQQSGFSVFVVGVADVDYNEL-----ANIASKPSER----HVFIVDDFESFEK 1327
Query: 485 TLQPLVKRVCDTDRLACSKTCLNS-ADIGFVIDGSSSVGTGNFRTV 529
L+ VC+T +C L+ GF + + ++ NF +V
Sbjct: 1328 IEDNLITFVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASV 1373
>gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]
Length = 957
Score = 115 bits (289), Expect = 1e-25
Identities = 64/178 (35%), Positives = 100/178 (56%), Gaps = 1/178 (0%)
Query: 510 DIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFGFDKYSS 569
D+ F++DGS SVG NF V +++ N+TK F+I ++G VQY+ LE Y S
Sbjct: 37 DLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKFIQVGVVQYSDYPVLEIPLGSYDS 96
Query: 570 KPDILNAIKRVGYWSGGTSTGAAINFALEQLFKKSKPNKRKLMILITDGRSYDDVRIPAM 629
+ A++ + Y G T TG AI FAL+ LF KS K+ +++TDG+S DDV+ A
Sbjct: 97 GEHLTAAVESILYLGGNTKTGKAIQFALDYLFAKSSRFLTKIAVVLTDGKSQDDVKDAAQ 156
Query: 630 AAHLKGVITYAIGVAWAAQE-ELEVIATHPARDHSFFVDEFDNLHQYVPRIIQNICTE 686
AA + +AIGV ++ EL IA P+ + F+V+++ + + + Q +C E
Sbjct: 157 AARDSKITLFAIGVGSETEDAELRAIANKPSSTYVFYVEDYIAISKIREVMKQKLCEE 214
Score = 95.5 bits (236), Expect = 1e-19
Identities = 57/188 (30%), Positives = 97/188 (51%), Gaps = 11/188 (5%)
Query: 308 DLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTN 367
DL F++DGS S+G F I K+ L ++ + DIGP +GVVQY D P L ++ +
Sbjct: 37 DLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKFIQVGVVQYSDYPVLEIPLGSYDS 96
Query: 368 SRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSGAPNVVVVMVDGWPTDKVEE 427
L A+E I GG + G+AI F F+K++ + VV+ DG D V++
Sbjct: 97 GEHLTAAVESILYLGGNTKTGKAIQFALDYLFAKSS---RFLTKIAVVLTDGKSQDDVKD 153
Query: 428 ASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWFGLHKTLQ 487
A++ AR+S I +F I + E+ + + ANK + Y +V+ + + K +
Sbjct: 154 AAQAARDSKITLFAIGVGSETEDAELRAI----ANK----PSSTYVFYVEDYIAISKIRE 205
Query: 488 PLVKRVCD 495
+ +++C+
Sbjct: 206 VMKQKLCE 213
>gi|62548862 matrilin 2 isoform b precursor [Homo sapiens]
Length = 937
Score = 115 bits (289), Expect = 1e-25
Identities = 64/194 (32%), Positives = 98/194 (50%), Gaps = 6/194 (3%)
Query: 497 DRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTY 556
D C K D+ FVIDGS S+G NF V QFVT + IS R+G +QY+
Sbjct: 642 DGRRCKKCTEGPIDLVFVIDGSKSLGEENFEVVKQFVTGIIDSLTISPKAARVGLLQYST 701
Query: 557 EQRLEFGFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQLFKKSKPNK------RK 610
+ EF ++S D+ A+ + Y G+ TG A+ E+ F + + + +
Sbjct: 702 QVHTEFTLRNFNSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQGEGARPLSTRVPR 761
Query: 611 LMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFVDEFD 670
I+ TDGR+ DDV A A G+ YA+GV A +EEL+ IA+ P H F+ ++F
Sbjct: 762 AAIVFTDGRAQDDVSEWASKAKANGITMYAVGVGKAIEEELQEIASEPTNKHLFYAEDFS 821
Query: 671 NLHQYVPRIIQNIC 684
+ + ++ + IC
Sbjct: 822 TMDEISEKLKKGIC 835
Score = 102 bits (253), Expect = 2e-21
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 7/189 (3%)
Query: 504 TCLNS-ADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEF 562
+C N AD+ F+ID S SV T ++ V +F+ ++ + +I TR+G +QY + EF
Sbjct: 50 SCENKRADLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLLQYGSTVKNEF 109
Query: 563 GFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQLFKKS------KPNKRKLMILIT 616
+ K ++ A+KR+ + S GT TG AI +AL F ++ + N ++++++T
Sbjct: 110 SLKTFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPRVIMIVT 169
Query: 617 DGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFVDEFDNLHQYV 676
DGR D V A A G++ +AIGV L+ I + P DH F V F +
Sbjct: 170 DGRPQDSVAEVAAKARDTGILIFAIGVGQVDFNTLKSIGSEPHEDHVFLVANFSQIETLT 229
Query: 677 PRIIQNICT 685
+ +CT
Sbjct: 230 SVFQKKLCT 238
Score = 87.8 bits (216), Expect = 3e-17
Identities = 48/144 (33%), Positives = 77/144 (53%), Gaps = 3/144 (2%)
Query: 304 NCKIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLK 363
N + DL F+ID S S+ + K+ + D+ Q LDIGP +G++QYG F+LK
Sbjct: 53 NKRADLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLLQYGSTVKNEFSLK 112
Query: 364 THTNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGN---RSGAPNVVVVMVDGW 420
T +++ A++++ + G AI + FS+A G R P V++++ DG
Sbjct: 113 TFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPRVIMIVTDGR 172
Query: 421 PTDKVEEASRLARESGINIFFITI 444
P D V E + AR++GI IF I +
Sbjct: 173 PQDSVAEVAAKARDTGILIFAIGV 196
Score = 84.7 bits (208), Expect = 3e-16
Identities = 46/152 (30%), Positives = 78/152 (51%), Gaps = 3/152 (1%)
Query: 307 IDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHT 366
IDL F+IDGS S+G+ F + KQ + + +L I P +G++QY T F L+
Sbjct: 654 IDLVFVIDGSKSLGEENFEVVKQFVTGIIDSLTISPKAARVGLLQYSTQVHTEFTLRNFN 713
Query: 367 NSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNR---SGAPNVVVVMVDGWPTD 423
+++D+K A+ + G S G A+ + + F++ G R + P +V DG D
Sbjct: 714 SAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQGEGARPLSTRVPRAAIVFTDGRAQD 773
Query: 424 KVEEASRLARESGINIFFITIEGAAENEKQYV 455
V E + A+ +GI ++ + + A E E Q +
Sbjct: 774 DVSEWASKAKANGITMYAVGVGKAIEEELQEI 805
>gi|62548860 matrilin 2 isoform a precursor [Homo sapiens]
Length = 956
Score = 115 bits (289), Expect = 1e-25
Identities = 64/194 (32%), Positives = 98/194 (50%), Gaps = 6/194 (3%)
Query: 497 DRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTY 556
D C K D+ FVIDGS S+G NF V QFVT + IS R+G +QY+
Sbjct: 642 DGRRCKKCTEGPIDLVFVIDGSKSLGEENFEVVKQFVTGIIDSLTISPKAARVGLLQYST 701
Query: 557 EQRLEFGFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQLFKKSKPNK------RK 610
+ EF ++S D+ A+ + Y G+ TG A+ E+ F + + + +
Sbjct: 702 QVHTEFTLRNFNSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQGEGARPLSTRVPR 761
Query: 611 LMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFVDEFD 670
I+ TDGR+ DDV A A G+ YA+GV A +EEL+ IA+ P H F+ ++F
Sbjct: 762 AAIVFTDGRAQDDVSEWASKAKANGITMYAVGVGKAIEEELQEIASEPTNKHLFYAEDFS 821
Query: 671 NLHQYVPRIIQNIC 684
+ + ++ + IC
Sbjct: 822 TMDEISEKLKKGIC 835
Score = 102 bits (253), Expect = 2e-21
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 7/189 (3%)
Query: 504 TCLNS-ADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEF 562
+C N AD+ F+ID S SV T ++ V +F+ ++ + +I TR+G +QY + EF
Sbjct: 50 SCENKRADLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLLQYGSTVKNEF 109
Query: 563 GFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQLFKKS------KPNKRKLMILIT 616
+ K ++ A+KR+ + S GT TG AI +AL F ++ + N ++++++T
Sbjct: 110 SLKTFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPRVIMIVT 169
Query: 617 DGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFVDEFDNLHQYV 676
DGR D V A A G++ +AIGV L+ I + P DH F V F +
Sbjct: 170 DGRPQDSVAEVAAKARDTGILIFAIGVGQVDFNTLKSIGSEPHEDHVFLVANFSQIETLT 229
Query: 677 PRIIQNICT 685
+ +CT
Sbjct: 230 SVFQKKLCT 238
Score = 87.8 bits (216), Expect = 3e-17
Identities = 48/144 (33%), Positives = 77/144 (53%), Gaps = 3/144 (2%)
Query: 304 NCKIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLK 363
N + DL F+ID S S+ + K+ + D+ Q LDIGP +G++QYG F+LK
Sbjct: 53 NKRADLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLLQYGSTVKNEFSLK 112
Query: 364 THTNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGN---RSGAPNVVVVMVDGW 420
T +++ A++++ + G AI + FS+A G R P V++++ DG
Sbjct: 113 TFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPRVIMIVTDGR 172
Query: 421 PTDKVEEASRLARESGINIFFITI 444
P D V E + AR++GI IF I +
Sbjct: 173 PQDSVAEVAAKARDTGILIFAIGV 196
Score = 84.7 bits (208), Expect = 3e-16
Identities = 46/152 (30%), Positives = 78/152 (51%), Gaps = 3/152 (1%)
Query: 307 IDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHT 366
IDL F+IDGS S+G+ F + KQ + + +L I P +G++QY T F L+
Sbjct: 654 IDLVFVIDGSKSLGEENFEVVKQFVTGIIDSLTISPKAARVGLLQYSTQVHTEFTLRNFN 713
Query: 367 NSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNR---SGAPNVVVVMVDGWPTD 423
+++D+K A+ + G S G A+ + + F++ G R + P +V DG D
Sbjct: 714 SAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQGEGARPLSTRVPRAAIVFTDGRAQD 773
Query: 424 KVEEASRLARESGINIFFITIEGAAENEKQYV 455
V E + A+ +GI ++ + + A E E Q +
Sbjct: 774 DVSEWASKAKANGITMYAVGVGKAIEEELQEI 805
>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
Length = 1626
Score = 113 bits (282), Expect = 7e-25
Identities = 67/197 (34%), Positives = 103/197 (52%), Gaps = 9/197 (4%)
Query: 494 CDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQ 553
C R C D+ F++D SSSVG +F V Q+V NL FE+ TR+G V+
Sbjct: 25 CQAQRAGCKSV---HYDLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVR 81
Query: 554 YTYEQRLEFGFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQLFKK---SKPNKR- 609
Y+ F + S+ ++ A +R+ Y G T+TG A+ + + F +P R
Sbjct: 82 YSDRPTTAFELGLFGSQEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRA 141
Query: 610 --KLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFVD 667
++ IL+TDGRS D V A AAH G+ +A+GV A +EELE IA+ P H F V
Sbjct: 142 YKQVAILLTDGRSQDLVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVS 201
Query: 668 EFDNLHQYVPRIIQNIC 684
+F+ + + ++ + +C
Sbjct: 202 DFNAIDKIRGKLRRRLC 218
Score = 92.8 bits (229), Expect = 9e-19
Identities = 57/192 (29%), Positives = 94/192 (48%), Gaps = 14/192 (7%)
Query: 308 DLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTN 367
DL FL+D S+S+GK F +Q +A++ ++GP +GVV+Y D P T F L +
Sbjct: 38 DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFEVGPDRTRVGVVRYSDRPTTAFELGLFGS 97
Query: 368 SRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNR---SGAPNVVVVMVDGWPTDK 424
++K A ++ GG +N G A+ ++T FS G R V +++ DG D
Sbjct: 98 QEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQVAILLTDGRSQDL 157
Query: 425 VEEASRLARESGINIFFITIEGAAENEKQYVV-EPNFANKAVCRTNGFYSLHVQSWFGLH 483
V +A+ A +GI IF + + A + E + + EP A + HV + +
Sbjct: 158 VLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSA----------HVFHVSDFNAID 207
Query: 484 KTLQPLVKRVCD 495
K L +R+C+
Sbjct: 208 KIRGKLRRRLCE 219
>gi|13699834 matrilin 4 isoform 2 precursor [Homo sapiens]
Length = 540
Score = 110 bits (276), Expect = 3e-24
Identities = 61/201 (30%), Positives = 102/201 (50%), Gaps = 6/201 (2%)
Query: 492 RVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGA 551
R D +C++ D+ ++DGS SV NF V +FV + ++S TR+G
Sbjct: 286 RQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGL 345
Query: 552 VQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQLFKKSKP----- 606
VQ++ R EF +Y + ++ A+ V Y GT TG A+ +E F +++
Sbjct: 346 VQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRA 405
Query: 607 -NKRKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFF 665
N ++ ++ TDGRS DD+ + A A +G++ YA+GV A + EL IA+ PA H +
Sbjct: 406 LNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSY 465
Query: 666 VDEFDNLHQYVPRIIQNICTE 686
+F + + + +IC E
Sbjct: 466 APDFGTMTHLLENLRGSICPE 486
Score = 94.7 bits (234), Expect = 2e-19
Identities = 56/181 (30%), Positives = 94/181 (51%), Gaps = 6/181 (3%)
Query: 510 DIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFGFDKYSS 569
D+ FVID S SV F T+ QF+ L + + TR+G +QY+ + + F +S
Sbjct: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
Query: 570 KPDILNAIKRVGYWSGGTSTGAAINFALEQLFKKSK----PNKR--KLMILITDGRSYDD 623
+ D+ AI+ + + GT TG AI +A+ F ++ P +R ++ +++TDGR D
Sbjct: 94 REDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDR 153
Query: 624 VRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFVDEFDNLHQYVPRIIQNI 683
V A A +G+ YA+GV A L +A+ P +H F V+ FD + ++ + +
Sbjct: 154 VAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQSRL 213
Query: 684 C 684
C
Sbjct: 214 C 214
Score = 79.7 bits (195), Expect = 8e-15
Identities = 49/167 (29%), Positives = 78/167 (46%), Gaps = 6/167 (3%)
Query: 298 VSLGDPNCK---IDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGD 354
+ L P C +DL F+ID S S+ F +Q L + + L++GP +GV+QY
Sbjct: 21 LQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSS 80
Query: 355 NPATHFNLKTHTNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNR---SGAPN 411
+ F L+ + D++ AI + + G AI + FS A G R P
Sbjct: 81 QVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPR 140
Query: 412 VVVVMVDGWPTDKVEEASRLARESGINIFFITIEGAAENEKQYVVEP 458
V V++ DG P D+V E + AR GI I+ + ++ A + + P
Sbjct: 141 VAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASP 187
Score = 71.6 bits (174), Expect = 2e-12
Identities = 44/156 (28%), Positives = 78/156 (50%), Gaps = 4/156 (2%)
Query: 307 IDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHT 366
+DL L+DGS S+ + F + K+ + + LD+ P G +G+VQ+ T F L +
Sbjct: 303 VDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYG 362
Query: 367 NSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSGA---PNVVVVMVDGWPTD 423
+ ++K A+ + + G A+ + ++ FS+A G R A P V +V DG D
Sbjct: 363 TAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQD 422
Query: 424 KVEEASRLARESGINIFFITIEGAAENE-KQYVVEP 458
+ + A+E GI ++ + + A E E ++ EP
Sbjct: 423 DISVWAARAKEEGIVMYAVGVGKAVEAELREIASEP 458
>gi|13699830 matrilin 4 isoform 1 precursor [Homo sapiens]
Length = 581
Score = 110 bits (276), Expect = 3e-24
Identities = 61/201 (30%), Positives = 102/201 (50%), Gaps = 6/201 (2%)
Query: 492 RVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGA 551
R D +C++ D+ ++DGS SV NF V +FV + ++S TR+G
Sbjct: 327 RQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGL 386
Query: 552 VQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQLFKKSKP----- 606
VQ++ R EF +Y + ++ A+ V Y GT TG A+ +E F +++
Sbjct: 387 VQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRA 446
Query: 607 -NKRKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFF 665
N ++ ++ TDGRS DD+ + A A +G++ YA+GV A + EL IA+ PA H +
Sbjct: 447 LNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSY 506
Query: 666 VDEFDNLHQYVPRIIQNICTE 686
+F + + + +IC E
Sbjct: 507 APDFGTMTHLLENLRGSICPE 527
Score = 94.7 bits (234), Expect = 2e-19
Identities = 56/181 (30%), Positives = 94/181 (51%), Gaps = 6/181 (3%)
Query: 510 DIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFGFDKYSS 569
D+ FVID S SV F T+ QF+ L + + TR+G +QY+ + + F +S
Sbjct: 34 DLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSR 93
Query: 570 KPDILNAIKRVGYWSGGTSTGAAINFALEQLFKKSK----PNKR--KLMILITDGRSYDD 623
+ D+ AI+ + + GT TG AI +A+ F ++ P +R ++ +++TDGR D
Sbjct: 94 REDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDR 153
Query: 624 VRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFVDEFDNLHQYVPRIIQNI 683
V A A +G+ YA+GV A L +A+ P +H F V+ FD + ++ + +
Sbjct: 154 VAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQSRL 213
Query: 684 C 684
C
Sbjct: 214 C 214
Score = 82.0 bits (201), Expect = 2e-15
Identities = 61/231 (26%), Positives = 96/231 (41%), Gaps = 17/231 (7%)
Query: 298 VSLGDPNCK---IDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGD 354
+ L P C +DL F+ID S S+ F +Q L + + L++GP +GV+QY
Sbjct: 21 LQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSS 80
Query: 355 NPATHFNLKTHTNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNR---SGAPN 411
+ F L+ + D++ AI + + G AI + FS A G R P
Sbjct: 81 QVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPR 140
Query: 412 VVVVMVDGWPTDKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGF 471
V V++ DG P D+V E + AR GI I+ + ++ A + + P
Sbjct: 141 VAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFL----V 196
Query: 472 YSLHVQSWFGLHKTLQPLVKRVCDTDRLACSKTCLNS-------ADIGFVI 515
S + FGL + +C C C+NS +GFV+
Sbjct: 197 ESFDLIQEFGLQFQSRLCAIDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVL 247
Score = 71.6 bits (174), Expect = 2e-12
Identities = 44/156 (28%), Positives = 78/156 (50%), Gaps = 4/156 (2%)
Query: 307 IDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHT 366
+DL L+DGS S+ + F + K+ + + LD+ P G +G+VQ+ T F L +
Sbjct: 344 VDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYG 403
Query: 367 NSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSGA---PNVVVVMVDGWPTD 423
+ ++K A+ + + G A+ + ++ FS+A G R A P V +V DG D
Sbjct: 404 TAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQD 463
Query: 424 KVEEASRLARESGINIFFITIEGAAENE-KQYVVEP 458
+ + A+E GI ++ + + A E E ++ EP
Sbjct: 464 DISVWAARAKEEGIVMYAVGVGKAVEAELREIASEP 499
>gi|38348304 von Willebrand factor A domain containing 2 [Homo
sapiens]
Length = 725
Score = 103 bits (256), Expect = 7e-22
Identities = 90/387 (23%), Positives = 160/387 (41%), Gaps = 27/387 (6%)
Query: 305 CKIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKT 364
C++DL FL+D S F K + +A+ + +GV Y +
Sbjct: 340 CRVDLLFLLDSSAGTTLDGFLRAKVFVKRFVRAVLSEDSRARVGVATYSRELLVAVPVGE 399
Query: 365 HTNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSGAPN-VVVVMVDGWPTD 423
+ + DL +++ I RGG + G A+ + F A P VVV++ + D
Sbjct: 400 YQDVPDLVWSLDGIPFRGGPTLTGSALRQAAERGFGSATRTGQDRPRRVVVLLTESHSED 459
Query: 424 KVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWFG-- 481
+V +R AR + + + E ++ P HV +
Sbjct: 460 EVAGPARHARARELLLLGVGSEAVRAELEEITGSPK---------------HVMVYSDPQ 504
Query: 482 -LHKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEF 540
L + L ++C R C L D+ F++D S+SVG NF + FV + +F
Sbjct: 505 DLFNQIPELQGKLCSRQRPGCRTQAL---DLVFMLDTSASVGPENFAQMQSFVRSCALQF 561
Query: 541 EISDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQL 600
E++ T++G V Y + + FG D ++ +L AI + Y G S G A+ +++
Sbjct: 562 EVNPDVTQVGLVVYGSQVQTAFGLDTKPTRAAMLRAISQAPYLGGVGSAGTALLHIYDKV 621
Query: 601 F---KKSKPNKRKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATH 657
+ ++P K ++++T GR +D +PA G+ +GV E L +A
Sbjct: 622 MTVQRGARPGVPKAVVVLTGGRGAEDAAVPAQKLRNNGISVLVVGVGPVLSEGLRRLA-- 679
Query: 658 PARDHSFFVDEFDNLHQYVPRIIQNIC 684
RD V + +L + +I+ +C
Sbjct: 680 GPRDSLIHVAAYADLRYHQDVLIEWLC 706
Score = 98.6 bits (244), Expect = 2e-20
Identities = 54/172 (31%), Positives = 91/172 (52%), Gaps = 9/172 (5%)
Query: 505 CLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFGF 564
C + DI F++DGS+SVG G+F F + +IS R+GA Q++ LEF
Sbjct: 46 CSAAVDIMFLLDGSNSVGKGSFERSKHFAITVCDGLDISPERVRVGAFQFSSTPHLEFPL 105
Query: 565 DKYSSKPDILNAIKRVGYWSGGTSTGAAINFALEQLFKKSKPNKR-----KLMILITDGR 619
D +S++ ++ IKR+ + G T T AL+ L + P R +++I++TDG+
Sbjct: 106 DSFSTQQEVKARIKRMVFKGGRTET----ELALKYLLHRGLPGGRNASVPQILIIVTDGK 161
Query: 620 SYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFVDEFDN 671
S DV +P+ +GV +A+GV + EEL +A+ P H ++ ++
Sbjct: 162 SQGDVALPSKQLKERGVTVFAVGVRFPRWEELHALASEPRGQHVLLAEQVED 213
Score = 74.3 bits (181), Expect = 3e-13
Identities = 52/208 (25%), Positives = 92/208 (44%), Gaps = 15/208 (7%)
Query: 275 PGSVLLDEGLVPKEELSTQSLEPVSLGDPNCKIDLSFLIDGSTSIGKRRFRIQKQLLADV 334
P S+ L E V KE + S + + +D+ FL+DGS S+GK F K V
Sbjct: 19 PPSLPLQEVHVSKETIGKISAASKMMWC-SAAVDIMFLLDGSNSVGKGSFERSKHFAITV 77
Query: 335 AQALDIGPAGPLMGVVQYGDNPATHFNLKTHTNSRDLKTAIEKITQRGGLSNVGRAISFV 394
LDI P +G Q+ P F L + + +++K I+++ +GG + A+ ++
Sbjct: 78 CDGLDISPERVRVGAFQFSSTPHLEFPLDSFSTQQEVKARIKRMVFKGGRTETELALKYL 137
Query: 395 TKNFFSKANGNRSGAPNVVVVMVDGWPTDKVEEASRLARESGINIFFITIEG-------- 446
G + P +++++ DG V S+ +E G+ +F + +
Sbjct: 138 LHR--GLPGGRNASVPQILIIVTDGKSQGDVALPSKQLKERGVTVFAVGVRFPRWEELHA 195
Query: 447 -AAENEKQYVVEPNFANKAVCRTNGFYS 473
A+E Q+V+ A + TNG +S
Sbjct: 196 LASEPRGQHVL---LAEQVEDATNGLFS 220
Score = 65.5 bits (158), Expect = 2e-10
Identities = 37/145 (25%), Positives = 64/145 (44%), Gaps = 3/145 (2%)
Query: 303 PNCK---IDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATH 359
P C+ +DL F++D S S+G F + + A ++ P +G+V YG T
Sbjct: 523 PGCRTQALDLVFMLDTSASVGPENFAQMQSFVRSCALQFEVNPDVTQVGLVVYGSQVQTA 582
Query: 360 FNLKTHTNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSGAPNVVVVMVDG 419
F L T + AI + GG+ + G A+ + + G R G P VVV+ G
Sbjct: 583 FGLDTKPTRAAMLRAISQAPYLGGVGSAGTALLHIYDKVMTVQRGARPGVPKAVVVLTGG 642
Query: 420 WPTDKVEEASRLARESGINIFFITI 444
+ ++ R +GI++ + +
Sbjct: 643 RGAEDAAVPAQKLRNNGISVLVVGV 667
>gi|11321565 matrilin 3 precursor [Homo sapiens]
Length = 486
Score = 99.8 bits (247), Expect = 8e-21
Identities = 56/181 (30%), Positives = 90/181 (49%), Gaps = 6/181 (3%)
Query: 510 DIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFGFDKYSS 569
D+ F+ID S SV F V FV+ + +I DTR+ V Y ++EF Y+
Sbjct: 83 DLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAVVNYASTVKIEFQLQAYTD 142
Query: 570 KPDILNAIKRVGYWSGGTSTGAAINFALEQLF------KKSKPNKRKLMILITDGRSYDD 623
K + A+ R+ S GT +G AI A+++ F ++ N K+ I++TDGR D
Sbjct: 143 KQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTVEAGAREPSSNIPKVAIIVTDGRPQDQ 202
Query: 624 VRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFVDEFDNLHQYVPRIIQNI 683
V A A G+ YA+GV A L+++A+ P +H F+V+ + + + R +
Sbjct: 203 VNEVAARAQASGIELYAVGVDRADMASLKMMASEPLEEHVFYVETYGVIEKLSSRFQETF 262
Query: 684 C 684
C
Sbjct: 263 C 263
Score = 79.3 bits (194), Expect = 1e-14
Identities = 64/230 (27%), Positives = 100/230 (43%), Gaps = 31/230 (13%)
Query: 228 LWSTATYTSSQNRPRADPGIQRQD---PSGAAFQKPVGADVSLGEMDSWKPGSVLLDEGL 284
LW S+ P A PG +R + P G+ ++P A
Sbjct: 17 LWPLLLLPSAAPDPVARPGFRRLETRGPGGSPGRRPSPA--------------------- 55
Query: 285 VPKEELSTQSLEPV-SLGDPNCK---IDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDI 340
P ++ + EP + G CK +DL F+ID S S+ F K ++ + LDI
Sbjct: 56 APDGAPASGTSEPGRARGAGVCKSRPLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDI 115
Query: 341 GPAGPLMGVVQYGDNPATHFNLKTHTNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFS 400
GPA + VV Y F L+ +T+ + LK A+ +IT + G AI F+
Sbjct: 116 GPADTRVAVVNYASTVKIEFQLQAYTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFT 175
Query: 401 KANGNR---SGAPNVVVVMVDGWPTDKVEEASRLARESGINIFFITIEGA 447
G R S P V +++ DG P D+V E + A+ SGI ++ + ++ A
Sbjct: 176 VEAGAREPSSNIPKVAIIVTDGRPQDQVNEVAARAQASGIELYAVGVDRA 225
>gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]
Length = 1284
Score = 98.2 bits (243), Expect = 2e-20
Identities = 53/153 (34%), Positives = 88/153 (57%), Gaps = 3/153 (1%)
Query: 509 ADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFGFDKYS 568
AD+ F++DGS S+G +F+ V F+ ++ FEI ++G QY+ + + E+ + S
Sbjct: 178 ADMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDLNSLS 237
Query: 569 SKPDILNAIKRVGYWSGGTSTGAAINFALEQLFKKS---KPNKRKLMILITDGRSYDDVR 625
+K +L A++R+ Y G T TG A+ L Q + + +P K++IL+TDG+S DDV
Sbjct: 238 TKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPEAAKVVILVTDGKSQDDVH 297
Query: 626 IPAMAAHLKGVITYAIGVAWAAQEELEVIATHP 658
A GV +A+GV A + EL ++A+ P
Sbjct: 298 TAARVLKDLGVNVFAVGVKNADEAELRLLASPP 330
Score = 89.0 bits (219), Expect = 1e-17
Identities = 48/156 (30%), Positives = 81/156 (51%)
Query: 303 PNCKIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNL 362
P D+ FL+DGS SIG F+ K LA V +IGP +G+ QY + T ++L
Sbjct: 174 PPVPADMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWDL 233
Query: 363 KTHTNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSGAPNVVVVMVDGWPT 422
+ + + A+ ++ +GG + G A++ V A G R A VV+++ DG
Sbjct: 234 NSLSTKEQVLAAVRRLRYKGGNTFTGLALTHVLGQNLQPAAGLRPEAAKVVILVTDGKSQ 293
Query: 423 DKVEEASRLARESGINIFFITIEGAAENEKQYVVEP 458
D V A+R+ ++ G+N+F + ++ A E E + + P
Sbjct: 294 DDVHTAARVLKDLGVNVFAVGVKNADEAELRLLASP 329
>gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]
Length = 1153
Score = 86.3 bits (212), Expect = 9e-17
Identities = 59/178 (33%), Positives = 97/178 (54%), Gaps = 19/178 (10%)
Query: 509 ADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFGFDKYS 568
+DI F+IDGS S+ +FR + +FV+ + + ++ + T +QY+ E R+ F F ++
Sbjct: 149 SDIAFLIDGSGSIIPHDFRRMKEFVSTVME--QLKKSKTLFSLMQYSEEFRIHFTFKEFQ 206
Query: 569 SKPDILNAIKRVGYWSGGTSTGAAINFALEQLF---KKSKPNKRKLMILITDGR------ 619
+ P+ + +K + G T T I + +LF ++ N K++++ITDG
Sbjct: 207 NNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVVITDGEKFGDPL 266
Query: 620 SYDDVRIPAMAAHLKGVITYAIGVAWA-----AQEELEVIATHPARDHSFFVDEFDNL 672
Y+DV IP A +GVI Y IGV A +++EL IA+ P RDH F V+ F+ L
Sbjct: 267 GYEDV-IP--EADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVNNFEAL 321
Score = 63.2 bits (152), Expect = 8e-10
Identities = 53/185 (28%), Positives = 84/185 (45%), Gaps = 17/185 (9%)
Query: 301 GDPNCKIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHF 360
G P D++FLIDGS SI FR K+ ++ V + L + L ++QY + HF
Sbjct: 143 GCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLK--KSKTLFSLMQYSEEFRIHF 200
Query: 361 NLKTHTNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSGAPNVVVVMVDGW 420
K N+ + ++ ++ ITQ G ++ I V + F+ NG R A ++VV+ DG
Sbjct: 201 TFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVVITDGE 260
Query: 421 P-------TDKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKA----VCRTN 469
D + EA R G+ + I + A +EK A+K V + N
Sbjct: 261 KFGDPLGYEDVIPEADR----EGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVN 316
Query: 470 GFYSL 474
F +L
Sbjct: 317 NFEAL 321
>gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]
Length = 1152
Score = 86.3 bits (212), Expect = 9e-17
Identities = 59/178 (33%), Positives = 97/178 (54%), Gaps = 19/178 (10%)
Query: 509 ADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFGFDKYS 568
+DI F+IDGS S+ +FR + +FV+ + + ++ + T +QY+ E R+ F F ++
Sbjct: 149 SDIAFLIDGSGSIIPHDFRRMKEFVSTVME--QLKKSKTLFSLMQYSEEFRIHFTFKEFQ 206
Query: 569 SKPDILNAIKRVGYWSGGTSTGAAINFALEQLF---KKSKPNKRKLMILITDGR------ 619
+ P+ + +K + G T T I + +LF ++ N K++++ITDG
Sbjct: 207 NNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVVITDGEKFGDPL 266
Query: 620 SYDDVRIPAMAAHLKGVITYAIGVAWA-----AQEELEVIATHPARDHSFFVDEFDNL 672
Y+DV IP A +GVI Y IGV A +++EL IA+ P RDH F V+ F+ L
Sbjct: 267 GYEDV-IP--EADREGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVNNFEAL 321
Score = 63.2 bits (152), Expect = 8e-10
Identities = 53/185 (28%), Positives = 84/185 (45%), Gaps = 17/185 (9%)
Query: 301 GDPNCKIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHF 360
G P D++FLIDGS SI FR K+ ++ V + L + L ++QY + HF
Sbjct: 143 GCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLK--KSKTLFSLMQYSEEFRIHF 200
Query: 361 NLKTHTNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSGAPNVVVVMVDGW 420
K N+ + ++ ++ ITQ G ++ I V + F+ NG R A ++VV+ DG
Sbjct: 201 TFKEFQNNPNPRSLVKPITQLLGRTHTATGIRKVVRELFNITNGARKNAFKILVVITDGE 260
Query: 421 P-------TDKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKA----VCRTN 469
D + EA R G+ + I + A +EK A+K V + N
Sbjct: 261 KFGDPLGYEDVIPEADR----EGVIRYVIGVGDAFRSEKSRQELNTIASKPPRDHVFQVN 316
Query: 470 GFYSL 474
F +L
Sbjct: 317 NFEAL 321
>gi|89191868 von Willebrand factor preproprotein [Homo sapiens]
Length = 2813
Score = 85.9 bits (211), Expect = 1e-16
Identities = 80/348 (22%), Positives = 150/348 (43%), Gaps = 28/348 (8%)
Query: 307 IDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHT 366
+D++F+++GS IG+ F K+ + +V Q +D+G + V+QY +
Sbjct: 1497 LDVAFVLEGSDKIGEADFNRSKEFMEEVIQRMDVGQDSIHVTVLQYSYMVTVEYPFSEAQ 1556
Query: 367 NSRDLKTAIEKITQRGG-LSNVGRAISFVTKNFFSKANGNRSGAPNVVVVMVDGWPTDKV 425
+ D+ + +I +GG +N G A+ +++ + F + G+R APN +V MV G P
Sbjct: 1557 SKGDILQRVREIRYQGGNRTNTGLALRYLSDHSFLVSQGDREQAPN-LVYMVTGNPAS-- 1613
Query: 426 EEASRLARESGINIFFITI-EGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWFGLHK 484
+E RL + I + I + A E + + PN + +Q + L +
Sbjct: 1614 DEIKRLPGD--IQVVPIGVGPNANVQELERIGWPN------------APILIQDFETLPR 1659
Query: 485 TLQPLVKRVC------DTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTK 538
LV + C L+ + C D+ ++DGSSS F + F
Sbjct: 1660 EAPDLVLQRCCSGEGLQIPTLSPAPDCSQPLDVILLLDGSSSFPASYFDEMKSFAKAFIS 1719
Query: 539 EFEISDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSGGTSTGAAINFALE 598
+ I T++ +QY ++ ++ K +L+ + + G + G A+ FA+
Sbjct: 1720 KANIGPRLTQVSVLQYGSITTIDVPWNVVPEKAHLLSLVDVMQREGGPSQIGDALGFAVR 1779
Query: 599 QLFKK---SKPNKRKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGV 643
L + ++P K ++++ S D V A AA V + IG+
Sbjct: 1780 YLTSEMHGARPGASKAVVILVTDVSVDSVDAAADAARSNRVTVFPIGI 1827
Score = 82.8 bits (203), Expect = 1e-15
Identities = 95/458 (20%), Positives = 183/458 (39%), Gaps = 74/458 (16%)
Query: 274 KPGSVLLD--EGLVPKEELSTQSLEPVSLGDPNCK--IDLSFLIDGSTSIGKRRFRIQKQ 329
+PG +++ + V L + + L D C +DL FL+DGS+ + + F + K
Sbjct: 1239 EPGGLVVPPTDAPVSPTTLYVEDISEPPLHDFYCSRLLDLVFLLDGSSRLSEAEFEVLKA 1298
Query: 330 LLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTNSRDLKTAIEKITQRGG-LSNVG 388
+ D+ + L I + VV+Y D + LK +L+ ++ G +++
Sbjct: 1299 FVVDMMERLRISQKWVRVAVVEYHDGSHAYIGLKDRKRPSELRRIASQVKYAGSQVASTS 1358
Query: 389 RAISFVTKNFFSKANGNRSGAPNVVVVMVDGWPTDKVEEASRLARESGINIFFITIEGAA 448
+ + FSK + R A + ++++ +E R++R F ++G
Sbjct: 1359 EVLKYTLFQIFSKID--RPEASRITLLLMAS------QEPQRMSRN-----FVRYVQGL- 1404
Query: 449 ENEKQYVVEP------------NFANKAVCRTNGFYSLHVQSWFGLHKTLQPLVKRVCDT 496
+K+ +V P K F V L + +V +CD
Sbjct: 1405 -KKKKVIVIPVGIGPHANLKQIRLIEKQAPENKAFVLSSVDE---LEQQRDEIVSYLCDL 1460
Query: 497 DRLACSKTC----------------------LNSA--DIGFVIDGSSSVGTGNFRTVLQF 532
A T NS D+ FV++GS +G +F +F
Sbjct: 1461 APEAPPPTLPPDMAQVTVGPGLLGVSTLGPKRNSMVLDVAFVLEGSDKIGEADFNRSKEF 1520
Query: 533 VTNLTKEFEISDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSGG-TSTGA 591
+ + + ++ + +QY+Y +E+ F + SK DIL ++ + Y G T+TG
Sbjct: 1521 MEEVIQRMDVGQDSIHVTVLQYSYMVTVEYPFSEAQSKGDILQRVREIRYQGGNRTNTGL 1580
Query: 592 AINFALEQLFKKSKPNKRK---LMILITDGRSYDDV-RIPAMAAHLKGVITYAIGVAWAA 647
A+ + + F S+ ++ + L+ ++T + D++ R+P + IGV A
Sbjct: 1581 ALRYLSDHSFLVSQGDREQAPNLVYMVTGNPASDEIKRLPG------DIQVVPIGVGPNA 1634
Query: 648 Q-EELEVIATHPARDHSFFVDEFDNLHQYVPRIIQNIC 684
+ELE I A + +F+ L + P ++ C
Sbjct: 1635 NVQELERIGWPNA---PILIQDFETLPREAPDLVLQRC 1669
Score = 66.2 bits (160), Expect = 9e-11
Identities = 69/297 (23%), Positives = 118/297 (39%), Gaps = 23/297 (7%)
Query: 218 SVGHRSQEMDLWSTATYTSSQNRPRADPGIQRQDPSGAAFQKPVGADVSLGEMD--SWKP 275
S G R Q +L T + + + PG + P G VG + ++ E++ W
Sbjct: 1593 SQGDREQAPNLVYMVTGNPASDEIKRLPGDIQVVPIG------VGPNANVQELERIGWPN 1646
Query: 276 GSVLLDE---------GLVPKEELSTQSLEPVSLGD-PNCK--IDLSFLIDGSTSIGKRR 323
+L+ + LV + S + L+ +L P+C +D+ L+DGS+S
Sbjct: 1647 APILIQDFETLPREAPDLVLQRCCSGEGLQIPTLSPAPDCSQPLDVILLLDGSSSFPASY 1706
Query: 324 FRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTNSRDLKTAIEKITQRGG 383
F K +IGP + V+QYG L + ++ + + GG
Sbjct: 1707 FDEMKSFAKAFISKANIGPRLTQVSVLQYGSITTIDVPWNVVPEKAHLLSLVDVMQREGG 1766
Query: 384 LSNVGRAISFVTKNFFSKANGNRSGAPNVVVVMVDGWPTDKVEEASRLARESGINIFFIT 443
S +G A+ F + S+ +G R GA VV++V D V+ A+ AR + + +F I
Sbjct: 1767 PSQIGDALGFAVRYLTSEMHGARPGASKAVVILVTDVSVDSVDAAADAARSNRVTVFPIG 1826
Query: 444 IEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWFG---LHKTLQPLVKRVCDTD 497
I + + ++ + V + L G LHK V+ D D
Sbjct: 1827 IGDRYDAAQLRILAGPAGDSNVVKLQRIEDLPTMVTLGNSFLHKLCSGFVRICMDED 1883
>gi|34452173 integrin alpha X precursor [Homo sapiens]
Length = 1163
Score = 84.7 bits (208), Expect = 3e-16
Identities = 61/177 (34%), Positives = 96/177 (54%), Gaps = 19/177 (10%)
Query: 510 DIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFGFDKYSS 569
DI F+IDGS S+ + NF T++ FV + +F+ T+ +Q++ + + F F+++
Sbjct: 151 DIVFLIDGSGSISSRNFATMMNFVRAVISQFQ--RPSTQFSLMQFSNKFQTHFTFEEFRR 208
Query: 570 KPDILNAIKRVGYWSGGTSTGAAINFALEQLFKKSKPNKR---KLMILITDGR------S 620
+ L+ + V G T T AI + +LF S +R K++I+ITDG+
Sbjct: 209 SSNPLSLLASVHQLQGFTYTATAIQNVVHRLFHASYGARRDAAKILIVITDGKKEGDSLD 268
Query: 621 YDDVRIPAMAAHLKGVITYAIGVAWAAQ-----EELEVIATHPARDHSFFVDEFDNL 672
Y DV A AA G+I YAIGV A Q +EL IA+ P+++H F V++FD L
Sbjct: 269 YKDVIPMADAA---GIIRYAIGVGLAFQNRNSWKELNDIASKPSQEHIFKVEDFDAL 322
Score = 46.6 bits (109), Expect = 8e-05
Identities = 36/129 (27%), Positives = 55/129 (42%), Gaps = 4/129 (3%)
Query: 292 TQSLEPVSLGD-PNCKIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVV 350
TQ L PVS + P + D+ FLIDGS SI R F + V ++
Sbjct: 135 TQRL-PVSRQECPRQEQDIVFLIDGSGSISSRNFATMMNFVRAVISQFQ--RPSTQFSLM 191
Query: 351 QYGDNPATHFNLKTHTNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSGAP 410
Q+ + THF + S + + + + Q G + AI V F + G R A
Sbjct: 192 QFSNKFQTHFTFEEFRRSSNPLSLLASVHQLQGFTYTATAIQNVVHRLFHASYGARRDAA 251
Query: 411 NVVVVMVDG 419
+++V+ DG
Sbjct: 252 KILIVITDG 260
>gi|62548866 integrin, alpha D precursor [Homo sapiens]
Length = 1161
Score = 83.2 bits (204), Expect = 7e-16
Identities = 62/196 (31%), Positives = 97/196 (49%), Gaps = 17/196 (8%)
Query: 510 DIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFGFDKYSS 569
DI F+IDGS S+ +F + FV + +FE TDT +QY+ ++ F F ++ +
Sbjct: 150 DIVFLIDGSGSIDQNDFNQMKGFVQAVMGQFE--GTDTLFALMQYSNLLKIHFTFTQFRT 207
Query: 570 KPDILNAIKRVGYWSGGTSTGAAINFALEQLF---KKSKPNKRKLMILITDGRSYDDVR- 625
P + + + G T T I + QLF ++ + +K++I+ITDG+ Y D
Sbjct: 208 SPSQQSLVDPIVQLKGLTFTATGILTVVTQLFHHKNGARKSAKKILIVITDGQKYKDPLE 267
Query: 626 ----IPAMAAHLKGVITYAIGVAWA-----AQEELEVIATHPARDHSFFVDEFDNLHQYV 676
IP A G+I YAIGV A A++EL I++ P +DH F VD F L
Sbjct: 268 YSDVIP--QAEKAGIIRYAIGVGHAFQGPTARQELNTISSAPPQDHVFKVDNFAALGSIQ 325
Query: 677 PRIIQNICTEFNSQPR 692
++ + I +Q R
Sbjct: 326 KQLQEKIYAVEGTQSR 341
Score = 51.6 bits (122), Expect = 2e-06
Identities = 33/117 (28%), Positives = 52/117 (44%), Gaps = 2/117 (1%)
Query: 303 PNCKIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNL 362
P+ ++D+ FLIDGS SI + F K + V + L ++QY + HF
Sbjct: 145 PHQEMDIVFLIDGSGSIDQNDFNQMKGFVQAVMGQFE--GTDTLFALMQYSNLLKIHFTF 202
Query: 363 KTHTNSRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSGAPNVVVVMVDG 419
S ++ ++ I Q GL+ I V F NG R A +++V+ DG
Sbjct: 203 TQFRTSPSQQSLVDPIVQLKGLTFTATGILTVVTQLFHHKNGARKSAKKILIVITDG 259
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,325,199
Number of Sequences: 37866
Number of extensions: 1238106
Number of successful extensions: 5427
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 60
Number of HSP's successfully gapped in prelim test: 130
Number of HSP's that attempted gapping in prelim test: 4264
Number of HSP's gapped (non-prelim): 971
length of query: 693
length of database: 18,247,518
effective HSP length: 109
effective length of query: 584
effective length of database: 14,120,124
effective search space: 8246152416
effective search space used: 8246152416
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.