BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|21359951 RNA binding motif protein 42 [Homo sapiens] (480 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|21359951 RNA binding motif protein 42 [Homo sapiens] 966 0.0 gi|110832843 TBP-associated factor 4 [Homo sapiens] 68 2e-11 gi|188219591 TIA1 protein isoform 2 [Homo sapiens] 67 3e-11 gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens] 66 6e-11 gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens] 66 6e-11 gi|188219593 TIA1 protein isoform 1 [Homo sapiens] 66 8e-11 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 65 1e-10 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 65 1e-10 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 64 3e-10 gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 62 1e-09 gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 62 1e-09 gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 62 1e-09 gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 61 2e-09 gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens] 61 3e-09 gi|242117971 RNA binding motif protein, X-linked-like 1 [Homo sa... 60 3e-09 gi|21361809 RNA binding motif protein, X-linked-like 1 [Homo sap... 60 3e-09 gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 60 4e-09 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 60 6e-09 gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 60 6e-09 gi|7706501 WW domain binding protein 11 [Homo sapiens] 60 6e-09 gi|56699409 RNA binding motif protein, X-linked [Homo sapiens] 59 7e-09 gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 59 1e-08 gi|4502847 cold inducible RNA binding protein [Homo sapiens] 59 1e-08 gi|223890219 RNA binding motif protein, X-linked-like 3 [Homo sa... 58 2e-08 gi|27436925 synoviolin 1 isoform a [Homo sapiens] 57 5e-08 gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] 57 5e-08 gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 56 8e-08 gi|153252068 testes-specific heterogenous nuclear ribonucleoprot... 56 8e-08 gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo s... 55 1e-07 gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens] 55 1e-07 >gi|21359951 RNA binding motif protein 42 [Homo sapiens] Length = 480 Score = 966 bits (2496), Expect = 0.0 Identities = 480/480 (100%), Positives = 480/480 (100%) Query: 1 MAGAGPAPGLPGAGGPVVPGPGAGIPGKSGEERLKEMEAEMALFEQEVLGAPVPGIPTAV 60 MAGAGPAPGLPGAGGPVVPGPGAGIPGKSGEERLKEMEAEMALFEQEVLGAPVPGIPTAV Sbjct: 1 MAGAGPAPGLPGAGGPVVPGPGAGIPGKSGEERLKEMEAEMALFEQEVLGAPVPGIPTAV 60 Query: 61 PAVPTVPTVPTVEAMQVPAAPVIRPIIATNTYQQVQQTLEARAAAAATVVPPMVGGPPFV 120 PAVPTVPTVPTVEAMQVPAAPVIRPIIATNTYQQVQQTLEARAAAAATVVPPMVGGPPFV Sbjct: 61 PAVPTVPTVPTVEAMQVPAAPVIRPIIATNTYQQVQQTLEARAAAAATVVPPMVGGPPFV 120 Query: 121 GPVGFGPGDRSHLDSPEAREAMFLRRAAVAPQRAPILRPAFVPHVLQRADSALSSAAAGP 180 GPVGFGPGDRSHLDSPEAREAMFLRRAAVAPQRAPILRPAFVPHVLQRADSALSSAAAGP Sbjct: 121 GPVGFGPGDRSHLDSPEAREAMFLRRAAVAPQRAPILRPAFVPHVLQRADSALSSAAAGP 180 Query: 181 RPMALRPPHQALVGPPLPGPPGPPMMLPPMARAPGPPLGSMAALRPPLEEPAAPRELGLG 240 RPMALRPPHQALVGPPLPGPPGPPMMLPPMARAPGPPLGSMAALRPPLEEPAAPRELGLG Sbjct: 181 RPMALRPPHQALVGPPLPGPPGPPMMLPPMARAPGPPLGSMAALRPPLEEPAAPRELGLG 240 Query: 241 LGLGLKEKEEAVVAAAAGLEEASAAVAVGAGGAPAGPAVIGPSLPLALAMPLPEPEPLPL 300 LGLGLKEKEEAVVAAAAGLEEASAAVAVGAGGAPAGPAVIGPSLPLALAMPLPEPEPLPL Sbjct: 241 LGLGLKEKEEAVVAAAAGLEEASAAVAVGAGGAPAGPAVIGPSLPLALAMPLPEPEPLPL 300 Query: 301 PLEVVRGLLPPLRIPELLSLRPRPRPPRPEPPPGLMALEVPEPLGEDKKKGKPEKLKRCI 360 PLEVVRGLLPPLRIPELLSLRPRPRPPRPEPPPGLMALEVPEPLGEDKKKGKPEKLKRCI Sbjct: 301 PLEVVRGLLPPLRIPELLSLRPRPRPPRPEPPPGLMALEVPEPLGEDKKKGKPEKLKRCI 360 Query: 361 RTAAGSSWEDPSLLEWDADDFRIFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGK 420 RTAAGSSWEDPSLLEWDADDFRIFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGK Sbjct: 361 RTAAGSSWEDPSLLEWDADDFRIFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGK 420 Query: 421 TKGYGFVSFKDPSDYVRAMREMNGKYVGSRPIKLRKSMWKDRNLDVVRKKQKEKKKLGLR 480 TKGYGFVSFKDPSDYVRAMREMNGKYVGSRPIKLRKSMWKDRNLDVVRKKQKEKKKLGLR Sbjct: 421 TKGYGFVSFKDPSDYVRAMREMNGKYVGSRPIKLRKSMWKDRNLDVVRKKQKEKKKLGLR 480 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 68.2 bits (165), Expect = 2e-11 Identities = 107/391 (27%), Positives = 132/391 (33%), Gaps = 71/391 (18%) Query: 2 AGAGPAPGLPGAGG--PVVPGPGAGIPGKSGEERLKEMEAEMALFEQEVLGAPVPGIPTA 59 AGAGPA GA G P P G PG G +R G P P P Sbjct: 71 AGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRP---------------GPPSPRRPL- 114 Query: 60 VPAVPTVPTV-----PTVEAMQVPAAPVIRPIIATNTYQQVQQTLEARAAAAATVVPPMV 114 VPA P P P A P + A A AA A P Sbjct: 115 VPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGP 174 Query: 115 GGPPFVGPVGFGPGDRSHLDSPEARE---AMFLRRAAVAPQRA----------PILRPAF 161 G P GP G GPG + + + A+ A AP + P+ +PA Sbjct: 175 GPGPGPGP-GPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAA 233 Query: 162 VPHVLQRADSALSSAAAGPRPMALRPPHQALVGPPLPGPPGPPMMLPPMARAPGPPLGSM 221 V+Q AAA P P A PP P PP PP +AR PG P G Sbjct: 234 PGTVIQTPPFV--GAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPP 291 Query: 222 AALRPPLEEPAAPRELGLGLGLGLKEKEEAVVAAAAGLEEASAAVAVGAGG--------- 272 A P + PAA + G A +G AA A A G Sbjct: 292 TA-APAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRV 350 Query: 273 -----------APAGPA------VIGPSLPLALAMPLPEPEPLP-LPLEVVRGLLPPLRI 314 A +GPA VIGP++ AL P P P P P + +G + Sbjct: 351 VQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAG--AV 408 Query: 315 PELLSLRPRPRPP--RPEPPPGLMALEVPEP 343 + LS P R P ++A +P+P Sbjct: 409 TQSLSRTPTATTSGIRATLTPTVLAPRLPQP 439 Score = 61.2 bits (147), Expect = 2e-09 Identities = 95/380 (25%), Positives = 128/380 (33%), Gaps = 80/380 (21%) Query: 2 AGAGPAPGLPGAGGPVVPGPGAGIPGKSGEERLKEMEAEMALFEQEVLGAPV-------- 53 AG GP PG PG G PGPG G P +G + + AL AP Sbjct: 170 AGPGPGPG-PGPG----PGPGPGKP--AGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGP 222 Query: 54 -------------------PGIPTAVPAVPTVPTVPTVEAMQVPAAPVIRPIIATNTYQQ 94 P + A P P P+ P A PAA P A T + Sbjct: 223 AALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLAR 282 Query: 95 VQQTLEARAAAAATVVPPMV-------GGPPFVGPVGFGPGDRSHLDSPEAREAMFLRRA 147 AA V PP G P P GP S P A A Sbjct: 283 PPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGA--------A 334 Query: 148 AVAPQRAPILRPAFVPHVLQRADSALSS-AAAGPRPMALRPPHQALVGPPLPGPPGPPMM 206 A AP AP ++ V+Q A A + AA+GP A ++GP + G P Sbjct: 335 AAAP--APGVKAESPKRVVQAAPPAAQTLAASGPASTAA----SMVIGPTMQGALPSPAA 388 Query: 207 LPPMARAPGPPLGSMAALRPPLEEPAAPRELGLGLGLGLKEKEEAVVAAAAGLEEASAAV 266 +PP A PG P G L + AA G + A +G+ A+ Sbjct: 389 VPPPA--PGTPTG--------LPKGAA--------GAVTQSLSRTPTATTSGIR-ATLTP 429 Query: 267 AVGAGGAPAGPA----VIGPSLPLALAMPLPEP-EPLPLPLEVVRGLLPPLRIPELLSLR 321 V A P P + LP + + E + L +P + + + ++ Sbjct: 430 TVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMA 489 Query: 322 PRPRPPRPEPPPGLMALEVP 341 PRP P PP + ++ P Sbjct: 490 PRPATPTSAPPVQISTVQAP 509 Score = 53.1 bits (126), Expect = 5e-07 Identities = 85/326 (26%), Positives = 102/326 (31%), Gaps = 57/326 (17%) Query: 88 ATNTYQQVQQTLEARAAAAATVVPPMVGGPPFVGPVGFGPG---DRSHLDSPEAREAMFL 144 A + + +T E RAAAA + +V G P G G GP + + +PE A Sbjct: 37 AAHHHHLAPRTPEVRAAAAGALGNHVVSGSP-AGAAGAGPAAPAEGAPGAAPEPPPAGRA 95 Query: 145 RRAAVAPQRA--PILRPAFVPHVLQRADSALSSAAAGPRPMA--LRPPHQALVGP----- 195 R PQR P R VP AGP P A LRPP + G Sbjct: 96 RPGGGGPQRPGPPSPRRPLVP--------------AGPAPPAAKLRPPPEGSAGSCAPVP 141 Query: 196 --------PLPGPPGPPMMLPPMARA----PGPPLGSMAALRPPLEEPAAPRELG-LGLG 242 P P P GP P A A PGP G P +PA P L Sbjct: 142 AAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGS 201 Query: 243 LGLKEKEEAVVAAAAGLEEASAAVA-----------------VGAGGAPAGPAVIGPSLP 285 L A A + + AA+ VGA PA A P+ P Sbjct: 202 AALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAP 261 Query: 286 LALAMPLPEPEPLPLPLEVVRGLLPPLRIPELLSLRPRPRPPRPEPPPGLMALEVPEPLG 345 A P P P P + R P P P P + G P G Sbjct: 262 APAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGG 321 Query: 346 EDKKKGKPEKLKRCIRTAAGSSWEDP 371 G+P A G E P Sbjct: 322 PAGVSGQPGPGAAAAAPAPGVKAESP 347 Score = 30.0 bits (66), Expect = 4.9 Identities = 20/68 (29%), Positives = 32/68 (47%), Gaps = 9/68 (13%) Query: 31 EERLKEMEAEMALFEQEVLGAPVPGIPTAVPAVPTVPTVPTVEAMQVPAAPVI-RPIIAT 89 ++ L +M+A+ Q + AP P PT+ P V + +Q P P+I R + T Sbjct: 470 QQALAQMQAQAHAQPQTTM-APRPATPTSAPPVQ-------ISTVQAPGTPIIARQVTPT 521 Query: 90 NTYQQVQQ 97 +QV Q Sbjct: 522 TIIKQVSQ 529 >gi|188219591 TIA1 protein isoform 2 [Homo sapiens] Length = 386 Score = 67.4 bits (163), Expect = 3e-11 Identities = 31/75 (41%), Positives = 48/75 (64%) Query: 379 DDFRIFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRA 438 D F +F GDL E+ + + AF+ F A+V++D TGK+KGYGFVSF + D A Sbjct: 104 DHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENA 163 Query: 439 MREMNGKYVGSRPIK 453 +++M G+++G R I+ Sbjct: 164 IQQMGGQWLGGRQIR 178 Score = 40.0 bits (92), Expect = 0.005 Identities = 21/93 (22%), Positives = 42/93 (45%), Gaps = 9/93 (9%) Query: 383 IFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREM 442 ++CG + + + + ++ + FS F ++ +V DK GY FV F A+ + Sbjct: 216 VYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVSV 269 Query: 443 NGKYVGSRPIKLRKSMWKDRNLDVVRKKQKEKK 475 NG + + K W LD++ Q++ + Sbjct: 270 NGTTIEGHVV---KCYWGKETLDMINPVQQQNQ 299 Score = 34.3 bits (77), Expect = 0.26 Identities = 23/97 (23%), Positives = 43/97 (44%), Gaps = 7/97 (7%) Query: 383 IFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREM 442 ++ G+L +V + ++ + FS+ K+I D T Y FV F + A+ M Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAAM 66 Query: 443 NGKYVGSRPIKLR-----KSMWKDRNLDVVRKKQKEK 474 NG+ + + +K+ S KD + V Q+ + Sbjct: 67 NGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQ 103 >gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens] Length = 392 Score = 66.2 bits (160), Expect = 6e-11 Identities = 34/99 (34%), Positives = 54/99 (54%), Gaps = 3/99 (3%) Query: 378 ADDFRIFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVR 437 ++ F +F GDL E+ + + AF+ F A+V++D TGK+KGYGFVSF + D Sbjct: 111 SNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAEN 170 Query: 438 AMREMNGKYVGSRPIKLRKSMWKDRNLDVVRKKQKEKKK 476 A+ M G+++G R I ++ W R + Q+ K Sbjct: 171 AIVHMGGQWLGGRQI---RTNWATRKPPAPKSTQENNTK 206 Score = 37.0 bits (84), Expect = 0.040 Identities = 20/90 (22%), Positives = 40/90 (44%), Gaps = 9/90 (10%) Query: 383 IFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREM 442 ++CG + + + D ++ + FS F ++ +V +K GY FV F A+ + Sbjct: 224 VYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESAAHAIVSV 277 Query: 443 NGKYVGSRPIKLRKSMWKDRNLDVVRKKQK 472 NG + + K W + D+ + Q+ Sbjct: 278 NGTTIEGHVV---KCYWGKESPDMTKNFQQ 304 Score = 31.2 bits (69), Expect = 2.2 Identities = 21/97 (21%), Positives = 43/97 (44%), Gaps = 15/97 (15%) Query: 373 LLEWDADDFRIFCGDLGNEVNDDILARAFSRFPSFLKAKVIRD----KRTGKTKG----- 423 ++E D ++ G+L +V + ++ + FS+ K+I + +R + G Sbjct: 1 MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQ 60 Query: 424 ------YGFVSFKDPSDYVRAMREMNGKYVGSRPIKL 454 Y FV F + D A+ MNG+ + + +K+ Sbjct: 61 HTSNDPYCFVEFYEHRDAAAALAAMNGRKILGKEVKV 97 >gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens] Length = 375 Score = 66.2 bits (160), Expect = 6e-11 Identities = 34/99 (34%), Positives = 54/99 (54%), Gaps = 3/99 (3%) Query: 378 ADDFRIFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVR 437 ++ F +F GDL E+ + + AF+ F A+V++D TGK+KGYGFVSF + D Sbjct: 94 SNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAEN 153 Query: 438 AMREMNGKYVGSRPIKLRKSMWKDRNLDVVRKKQKEKKK 476 A+ M G+++G R I ++ W R + Q+ K Sbjct: 154 AIVHMGGQWLGGRQI---RTNWATRKPPAPKSTQENNTK 189 Score = 37.0 bits (84), Expect = 0.040 Identities = 20/90 (22%), Positives = 40/90 (44%), Gaps = 9/90 (10%) Query: 383 IFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREM 442 ++CG + + + D ++ + FS F ++ +V +K GY FV F A+ + Sbjct: 207 VYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEK------GYSFVRFSTHESAAHAIVSV 260 Query: 443 NGKYVGSRPIKLRKSMWKDRNLDVVRKKQK 472 NG + + K W + D+ + Q+ Sbjct: 261 NGTTIEGHVV---KCYWGKESPDMTKNFQQ 287 Score = 34.7 bits (78), Expect = 0.20 Identities = 19/82 (23%), Positives = 40/82 (48%), Gaps = 2/82 (2%) Query: 373 LLEWDADDFRIFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDP 432 ++E D ++ G+L +V + ++ + FS+ K+I + + Y FV F + Sbjct: 1 MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDP--YCFVEFYEH 58 Query: 433 SDYVRAMREMNGKYVGSRPIKL 454 D A+ MNG+ + + +K+ Sbjct: 59 RDAAAALAAMNGRKILGKEVKV 80 >gi|188219593 TIA1 protein isoform 1 [Homo sapiens] Length = 375 Score = 65.9 bits (159), Expect = 8e-11 Identities = 30/76 (39%), Positives = 49/76 (64%) Query: 378 ADDFRIFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVR 437 ++ F +F GDL E+ + + AF+ F A+V++D TGK+KGYGFVSF + D Sbjct: 92 SNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAEN 151 Query: 438 AMREMNGKYVGSRPIK 453 A+++M G+++G R I+ Sbjct: 152 AIQQMGGQWLGGRQIR 167 Score = 40.0 bits (92), Expect = 0.005 Identities = 21/93 (22%), Positives = 42/93 (45%), Gaps = 9/93 (9%) Query: 383 IFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREM 442 ++CG + + + + ++ + FS F ++ +V DK GY FV F A+ + Sbjct: 205 VYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDK------GYSFVRFNSHESAAHAIVSV 258 Query: 443 NGKYVGSRPIKLRKSMWKDRNLDVVRKKQKEKK 475 NG + + K W LD++ Q++ + Sbjct: 259 NGTTIEGHVV---KCYWGKETLDMINPVQQQNQ 288 Score = 33.5 bits (75), Expect = 0.44 Identities = 18/72 (25%), Positives = 35/72 (48%), Gaps = 2/72 (2%) Query: 383 IFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREM 442 ++ G+L +V + ++ + FS+ K+I D T Y FV F + A+ M Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAAM 66 Query: 443 NGKYVGSRPIKL 454 NG+ + + +K+ Sbjct: 67 NGRKIMGKEVKV 78 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 65.5 bits (158), Expect = 1e-10 Identities = 79/328 (24%), Positives = 117/328 (35%), Gaps = 60/328 (18%) Query: 54 PGIPTAVPAVPTVPTVPTVEAMQVPAAPVIRPIIATNTYQ-----QVQQTLEARA----- 103 P P+A P++ T+P+ P Q P + P+ A + Q QV +L + + Sbjct: 345 PPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPP 404 Query: 104 ---AAAATVVPPMVGGPPFVGPVGF--------------------GPGDRSHLDSPEARE 140 A ++ +G P F P D L +P + Sbjct: 405 SPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLP 464 Query: 141 AMFLRRAAVAPQRAPILRPAFVPHVLQRADSALSSAAAGPRPMALRPPHQALVGPPLPGP 200 A + +++P +P+ P + H LQ S S + P + PP + Sbjct: 465 ASPPLQTSLSPAVSPLSSPLTI-HPLQALSSLASHSPQAPLSSLIMPPLET------QSS 517 Query: 201 PGPPMMLPPMARAPGPPLGSMAALR-PPLEEPAAPRELGLGLGLGLKEKEEAVVAAAAGL 259 PP + P A PPL ++ +L PPL+ +AP L E A L Sbjct: 518 LAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAP--------LTTPHLETPPCPAPCPL 569 Query: 260 EEASAAVAVGAGGAPAGPAVIGPSLPLALAMP----LPEPEPLPLPLEVVRGLLPPLRIP 315 + + + P+ A P P ALA P LP P PL PP + P Sbjct: 570 QAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPL-------ATPPPQAP 622 Query: 316 ELLSLRPRPRPPRPEPPPGLMALEVPEP 343 L+L P PP P P L L P P Sbjct: 623 PXLALPPLQAPPSPPASPPLSPLATPSP 650 Score = 63.5 bits (153), Expect = 4e-10 Identities = 82/300 (27%), Positives = 108/300 (36%), Gaps = 35/300 (11%) Query: 38 EAEMALFEQEVLGAPVPGIPTAVPAVPTVPTVPTVEAMQVPAAPVIRPIIA--TNTYQQV 95 +A AL + G P P + P P + +Q P +P P ++ Q Sbjct: 593 QAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQA 652 Query: 96 QQTLEARAAAAATVVPPMVGGPPFVGPVGFGPGDRSHLDSPEAREAMFLRRAAVAPQRAP 155 L A PP PP P SP A + +A P +AP Sbjct: 653 PNALAVHLLQAPFSPPP---SPPVQAPF-----------SPPASPP--VSPSATPPSQAP 696 Query: 156 ILRPAFVPHVLQRADSALSSAAAGPRPMALRPPHQA---LVGPPLPGPPGPPMMLPPMAR 212 P+ LQ S +S P + PP QA L PPL PP PP P Sbjct: 697 ---PSLAAPPLQVPPSPPASPPMSP---SATPPPQAPPPLAAPPLQVPPSPPASPPMSPS 750 Query: 213 APGPPLGSMAALRPPLEEPAAPRELGLGLGLGLKEKEEAVVA-AAAGLEEASAAVAVGAG 271 A PP PPL+ P +P L + K +A A A L+ + A G Sbjct: 751 ATPPPRVPPLLAAPPLQVPPSP-PASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPG 809 Query: 272 GAPAGPAVIGPSLPLALAMPLPEPEPLPLPLEVVRGLLPPLRIPELLSLRPRPRPPRPEP 331 AP P+ SLP++ PL P P P+ L P P +L+ RPP P P Sbjct: 810 QAPFSPSA---SLPMS---PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP 863 Score = 59.7 bits (143), Expect = 6e-09 Identities = 79/310 (25%), Positives = 108/310 (34%), Gaps = 41/310 (13%) Query: 54 PGIPTAV-PAVPTVPTVPTVEAMQV--------PAAPVIRPIIATNTYQQVQQTLEARAA 104 P + T++ PAV + + T+ +Q P AP+ I+ Q + Sbjct: 467 PPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTP 526 Query: 105 AAATVVPPMVGGPPFVGP---VGFGPGDRSHLDSPEAREAMFLRRAAVAPQRAPILRPAF 161 A+ PP+ P P P HL++P A P +AP Sbjct: 527 PASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPC--------PAPCPLQAP------ 572 Query: 162 VPHVLQRADSALSSAAAGPRPMALRPPHQALVGPPLPGPPGPPMMLPPMARAP--GPPLG 219 P L S+ A P P A PP AL PPL G P PP L P+A P PP Sbjct: 573 -PSPLTTPPPETPSSIATPPPQA--PP--ALASPPLQGLPSPP--LSPLATPPPQAPPXL 625 Query: 220 SMAALRPPLEEPAAPRELGLGLGLGLKEKEEAVVAAAAGLEEASAAVAVGAGGAPAGPAV 279 ++ L+ P PA+P L AV A + PA P V Sbjct: 626 ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 685 Query: 280 IGPSLPLALAMPLPEPEPLPLPLE------VVRGLLPPLRIPELLSLRPRPRPPRPEPPP 333 + P + A P PL +P + PP + P L+ P PP P P Sbjct: 686 SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP 745 Query: 334 GLMALEVPEP 343 + P P Sbjct: 746 PMSPSATPPP 755 Score = 59.3 bits (142), Expect = 7e-09 Identities = 85/318 (26%), Positives = 110/318 (34%), Gaps = 54/318 (16%) Query: 51 APVPGIPTAVPAVPTVPTVPTVEAMQVPAAPVIRPIIATNTYQQVQQTLEARAAAAATVV 110 A P P A P+ P P V +Q P +P P + + + +A + Sbjct: 638 ASPPLSPLATPS-PQAPNALAVHLLQAPFSPPPSPPVQA-PFSPPASPPVSPSATPPSQA 695 Query: 111 PPMVGGPPFVGPVGFGPGDRSHLDSPEAREAMFLRRAAVAPQRAPILRPAFVPHVLQRAD 170 PP + PP P SP A M +A P +AP P LQ Sbjct: 696 PPSLAAPPLQVP-----------PSPPASPPM--SPSATPPPQAP---PPLAAPPLQVPP 739 Query: 171 SALSSAAAGPRPMALRPPH--QALVGPPLPGPPGPPMMLPPMARAPGPPLGSMAALRPPL 228 S +S P A PP L PPL PP PP LP A PP A PPL Sbjct: 740 SPPASPPMSPS--ATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPL 797 Query: 229 EEPAAPRELGLGLGLGLKEKEEAVVAAAAGLEEASAAVAVGAGGAPAGPAVIG------- 281 + +P G +A + +A L + A P P V+ Sbjct: 798 QALPSPPASFPG---------QAPFSPSASLPMSPLATP-----PPQAPPVLAAPLLQVP 843 Query: 282 PSLPLALAMPLPEPEPLPLPLEVVRGLLPPLRIPEL-LSLRPRPRPPRPEPPPGLMALEV 340 PS P + + P P P P V G P L L+L P P PP P L Sbjct: 844 PSPPASPTLQAPRRPPTPGPDTSVSG-------PRLTLALAPGPPPPPSRSPSS--TLSG 894 Query: 341 PEPLGEDKK-KGKPEKLK 357 P+ G PE+L+ Sbjct: 895 PDLAGHSSSATSTPEELR 912 Score = 43.9 bits (102), Expect = 3e-04 Identities = 85/342 (24%), Positives = 111/342 (32%), Gaps = 40/342 (11%) Query: 16 PVVPGPGAGIPGKSGEERLKEMEAEMALFEQEVLGAPVPGIPTAVPAVPTVPTVPTVEAM 75 P PG P G R AL VLGA AV P + Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAAL---RVLGAA-----GAVGRKPLAERAGGIGGA 68 Query: 76 QVP-AAPVIRPIIATNTYQQVQQTLEARAAAAATVVPPMVGGPPFVGPVGFGPGDRSHLD 134 +P +AP P + T + A+ PP P GPV PG S Sbjct: 69 TIPESAPRAGPTRSAGTSSR-NPASRPPASGRGERAPPAKNTSP--GPVS-SPGRASGTT 124 Query: 135 SP----------EAREAMFLRRAAVAPQRAPILRPAFVPHVLQRADSALSSAAAGPRPMA 184 P A E + +A AP+R+ + A R D++ P P Sbjct: 125 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGA-------RRDTS-GPTPGTPSPAM 176 Query: 185 LRPPHQA--LVGPPLPGPPGPPMMLPPMARAPGPPLGSMAALRPPLEEPAAPRELGLGLG 242 R A VG P P P P PP GP +A EP+ G Sbjct: 177 ARRSRAAGTEVGLPRPAPSARPR--PP---TEGPRKSVSSASEHSTTEPSPAARRRPSAG 231 Query: 243 LGLKEKEEAVVAAAAGLEEASAAVAVGAGGAPAGPAVIGPSLPLALAMPLPEPEPLPLPL 302 GL+ ++++A + A A G P PA PS P + P + P Sbjct: 232 GGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPA--HPSQPKPKGLQALRPPQVTPPR 289 Query: 303 EVVRGLLPPLRIPELLSLRPRPRPPRPEPPPGLMALEVPEPL 344 + L PL L + P RP PPP A +P L Sbjct: 290 KDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATL 331 Score = 42.7 bits (99), Expect = 7e-04 Identities = 58/230 (25%), Positives = 85/230 (36%), Gaps = 24/230 (10%) Query: 130 RSHLDSPEAREAMFLRRAAVAPQRAPILRPAFVPHVLQRADSALSSAAAGPRPMALRPPH 189 R + P + + P A RP+ + + A +LSS+A L P Sbjct: 199 RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT-----PLSSPA 253 Query: 190 QALVGPPLPGPPGPPMMLPPMARAPGPPLGSMAALRPPLEEPAAPRELGLGLGLGLKEKE 249 ++ GP G P P A P + ALRPP P PR+ LG Sbjct: 254 RS--GPSARGTPRAP------AHPSQPKPKGLQALRPPQVTP--PRK-DAAPALGPLSSS 302 Query: 250 EAVVAAAAGLEEASAAVAVGAGGAPAGPAVIGPSLPLALAMPLPEPEP-LPLPLEVVRG- 307 + +G + + V A PA + PS PLA +PL P P P L+ + Sbjct: 303 PLATPSPSGTK--ARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSP 360 Query: 308 -LLPPLRIPELLSLRPRPRPPRPEPPPGLMALEVPEPLGEDKKKGKPEKL 356 PP + P ++ P PP + P ++VP L + P L Sbjct: 361 PATPPSQAPPSMTTPPMQAPPSLQTIP---PIQVPHSLTSPSLQAPPSPL 407 Score = 37.4 bits (85), Expect = 0.030 Identities = 65/251 (25%), Positives = 85/251 (33%), Gaps = 31/251 (12%) Query: 6 PAPGLPGAGGP---VVPGPGAGIPGKSGEERLKEMEAEMALFEQEVLGAPV---PGIPTA 59 P+ P P V P P A P + +A +V +P P P+A Sbjct: 692 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSA 751 Query: 60 VPAVPTVPTVPTVEAMQVPAAPVIRPIIATNTYQQVQQTLEARAAAAATVVPPM--VGGP 117 P P VP + +QVP +P ++ Q A A PP+ + P Sbjct: 752 TPP-PRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQ-------APPALATPPLQALPSP 803 Query: 118 P--FVGPVGFGPG---DRSHLDSPEARE----AMFLRRAAVAPQRAPILR-----PAFVP 163 P F G F P S L +P + A L + +P +P L+ P P Sbjct: 804 PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP 863 Query: 164 HVLQRADSALSSAAAGPRPMALRPPHQALVGPPLPGPPGPPMMLPPMARA-PGPPLGSMA 222 + A GP P R P L GP L G P R P G A Sbjct: 864 DTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAA 923 Query: 223 ALRPPLEEPAA 233 A PP E AA Sbjct: 924 ASPPPDAELAA 934 Score = 31.6 bits (70), Expect = 1.7 Identities = 58/226 (25%), Positives = 76/226 (33%), Gaps = 29/226 (12%) Query: 170 DSALSSAAAGPRPMALRPPHQALVGPPLPGPPGPPMMLPPMARAPGPPLGSMAALRPPLE 229 D+ A AG A R P G P PPG P PP+ A LG+ A+ Sbjct: 2 DNKRDKAKAGA---AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVG---R 55 Query: 230 EPAAPRELGLGLGLGLKEKEEAVVAAAAGLEE---ASAAVAVGAG--GAPAGPAVIGPSL 284 +P A R G+G + A +AG AS A G G PA GP Sbjct: 56 KPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVS 115 Query: 285 PLALAMPLPEPEPL-------PLPLEVVRGLL--PPLRIPELLSLRPRPRPPRPEPPPGL 335 A P PL V RG P R R P P P Sbjct: 116 SPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPA 175 Query: 336 MA---------LEVPEPLGEDKKKGKPEKLKRCIRTAAGSSWEDPS 372 MA + +P P + + E ++ + +A+ S +PS Sbjct: 176 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPS 221 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 65.1 bits (157), Expect = 1e-10 Identities = 85/328 (25%), Positives = 114/328 (34%), Gaps = 43/328 (13%) Query: 49 LGAPVPGIPTAVPAVPTVPTVPTVEAMQVPAAPVIRPIIATNTYQQVQQTLEARAAAAAT 108 L P P P ++ +P+ P P +A +P ++ T+ + + A Sbjct: 340 LAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQA-----THSFLPSPPLSPLATPPP 394 Query: 109 VVPPMVGGPPFVGPVG---FGPGDRSHLDSPEAREAMFLRRAAVAPQRAPILRPAFVPHV 165 PP + PP P P SP+A A+ AV +AP P P Sbjct: 395 QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNAL-----AVHLLQAPFSPPPSPP-- 447 Query: 166 LQRADSALSSAAAGPRPMALRPPHQA---LVGPPLPGPPGPPMMLPPMARAPGPPLGSMA 222 + S A+ P + PP QA L PPL PP PP P A PP Sbjct: 448 ---VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 504 Query: 223 ALRPPLE----EPAAPRELGLGLGLGLKEKEEAVVAAAAGLEEASAAVAVGAGGAPAGPA 278 PPL+ P AP L L + A AS ++ A P P Sbjct: 505 LAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 564 Query: 279 VIG-------PSLPLALAMPLPEPEPLPLPLEVVRGLLPPLRIPEL-LSLRPRPRPPRPE 330 V+ PS P + + P P P P V G P L L+L P P PP Sbjct: 565 VLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG-------PRLTLALAPGPPPPPSR 617 Query: 331 PPPGLMALEVPEPLGEDKK-KGKPEKLK 357 P L P+ G PE+L+ Sbjct: 618 SPSS--TLSGPDLAGHSSSATSTPEELR 643 Score = 48.9 bits (115), Expect = 1e-05 Identities = 85/375 (22%), Positives = 118/375 (31%), Gaps = 63/375 (16%) Query: 4 AGPAPGLPGAGGPVVPGPGAGIPGKSGEERLKEMEAEMALFEQEVLGAPVPGIPTAVPAV 63 AG GLP P P P KS + E + + P G PA Sbjct: 183 AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR---RPSAGGGLQRPAS 239 Query: 64 PTVPTVPTVEAMQVPAAPVIRPIIATNTYQQVQQTLEARAAAAATVVPPMVGGPPFVGPV 123 ++ + T + + P R + + +A V PP P +GP+ Sbjct: 240 RSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPL 299 Query: 124 GFGPGDRSHLDSPEAREAMFLRRAAVAPQRAPILRPAFVPHVLQRADSALSSAAAGPRPM 183 P L +P A+ +AP PA PH S+L+ A P P+ Sbjct: 300 SSSP-----LATPSPSAAL--------QSQAPPTLPA-TPH-----SSSLTCQLATPLPL 340 Query: 184 ALRPPHQALVGPPLPGPP-----------GPPMMLPPMARAPGPPLGSMAA--------- 223 A P LP PP G P + + P PPL +A Sbjct: 341 APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 400 Query: 224 LRPPLEEPAAPRELGLGLGLGLKEKEEAVVAAAAGLEEASAAVAVGAGGAPAGPAVIGPS 283 PPL+ P +P + A +A A+AV AP P PS Sbjct: 401 ALPPLQAPPSP------------PASPPLSPLATPSPQAPNALAVHLLQAPFSPP---PS 445 Query: 284 LPLALAMPLPEPEPLPLPLEVVRGLLPPLRIPELLSLRPRPRPPRPEPPPGLMALEVPEP 343 P+ P P V PP + P L+ P PP P P + P P Sbjct: 446 PPVQAPFSPPASPP------VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 499 Query: 344 LGEDKKKGKPEKLKR 358 P +L + Sbjct: 500 QAPPPLAAPPLQLAK 514 Score = 37.7 bits (86), Expect = 0.023 Identities = 77/288 (26%), Positives = 95/288 (32%), Gaps = 72/288 (25%) Query: 49 LGAPVPGIPTAVPAVPTVPTVPTVEAMQVPAAPVIRPIIATNTYQQVQQTLEARAAAAAT 108 L AP +P + PA P P P+ A P AP P +A Q + +A A A Sbjct: 474 LAAPPLQVPPSPPASP--PMSPS--ATPPPQAP---PPLAAPPLQLAKPPPQAPPALAT- 525 Query: 109 VVPPM--VGGPP--FVGPVGFGPG---DRSHLDSPEARE----AMFLRRAAVAPQRAPIL 157 PP+ + PP F G F P S L +P + A L + +P +P L Sbjct: 526 --PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL 583 Query: 158 R-----PAFVPHVLQRADSALSSAAAGPRPMALRPPHQALVGPPLPG------------- 199 + P P + A GP P R P L GP L G Sbjct: 584 QAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 643 Query: 200 -----PPGPPMMLPP------------MARAPGPPLGSMAALRPPLEEPAAPRELGLGLG 242 P G PP +R P PPL A PL P A G G Sbjct: 644 GYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPA---TGPGSA 700 Query: 243 LGL------KEKEEAVVAAAA-------GLEEASAAVAVGAGGAPAGP 277 GL + E A A A G AA GAG + P Sbjct: 701 DGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP 748 Score = 31.6 bits (70), Expect = 1.7 Identities = 58/226 (25%), Positives = 76/226 (33%), Gaps = 29/226 (12%) Query: 170 DSALSSAAAGPRPMALRPPHQALVGPPLPGPPGPPMMLPPMARAPGPPLGSMAALRPPLE 229 D+ A AG A R P G P PPG P PP+ A LG+ A+ Sbjct: 2 DNKRDKAKAGA---AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVG---R 55 Query: 230 EPAAPRELGLGLGLGLKEKEEAVVAAAAGLEE---ASAAVAVGAG--GAPAGPAVIGPSL 284 +P A R G+G + A +AG AS A G G PA GP Sbjct: 56 KPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVS 115 Query: 285 PLALAMPLPEPEPL-------PLPLEVVRGLL--PPLRIPELLSLRPRPRPPRPEPPPGL 335 A P PL V RG P R R P P P Sbjct: 116 SPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPA 175 Query: 336 MA---------LEVPEPLGEDKKKGKPEKLKRCIRTAAGSSWEDPS 372 MA + +P P + + E ++ + +A+ S +PS Sbjct: 176 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPS 221 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 63.9 bits (154), Expect = 3e-10 Identities = 84/325 (25%), Positives = 113/325 (34%), Gaps = 43/325 (13%) Query: 52 PVPGIPTAVPAVPTVPTVPTVEAMQVPAAPVIRPIIATNTYQQVQQTLEARAAAAATVVP 111 P P P ++ +P+ P P +A +P ++ T+ + + A P Sbjct: 304 PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQA-----THSFLPSPPLSPLATPPPQAP 358 Query: 112 PMVGGPPFVGPVG---FGPGDRSHLDSPEAREAMFLRRAAVAPQRAPILRPAFVPHVLQR 168 P + PP P P SP+A A+ AV +AP P P Sbjct: 359 PALALPPLQAPPSPPASPPLSPLATPSPQAPNAL-----AVHLLQAPFSPPPSPP----- 408 Query: 169 ADSALSSAAAGPRPMALRPPHQA---LVGPPLPGPPGPPMMLPPMARAPGPPLGSMAALR 225 + S A+ P + PP QA L PPL PP PP P A PP Sbjct: 409 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA 468 Query: 226 PPLE----EPAAPRELGLGLGLGLKEKEEAVVAAAAGLEEASAAVAVGAGGAPAGPAVIG 281 PPL+ P AP L L + A AS ++ A P P V+ Sbjct: 469 PPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 528 Query: 282 -------PSLPLALAMPLPEPEPLPLPLEVVRGLLPPLRIPEL-LSLRPRPRPPRPEPPP 333 PS P + + P P P P V G P L L+L P P PP P Sbjct: 529 APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG-------PRLTLALAPGPPPPPSRSPS 581 Query: 334 GLMALEVPEPLGEDKK-KGKPEKLK 357 L P+ G PE+L+ Sbjct: 582 S--TLSGPDLAGHSSSATSTPEELR 604 Score = 55.8 bits (133), Expect = 8e-08 Identities = 99/403 (24%), Positives = 129/403 (32%), Gaps = 79/403 (19%) Query: 5 GPAPGLPGAGGPVVPGP----GAGIPGKSGEERLKEMEAE----MALFEQEVLGAPVPGI 56 GP A G PGP G I + R K EA ++ + P PG Sbjct: 103 GPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGT 162 Query: 57 PTAVPAVPTVPTVPTVEAMQVPAAPVIRPIIATN----TYQQVQQTLEARAAAAATVVPP 112 P+ PA+ E AP RP T + + + AA P Sbjct: 163 PS--PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPS 220 Query: 113 MVGG-------------PPFVGPVGFGPGDR------SHLDSPEAREAMFLRRAAVAPQR 153 GG P P GP R +H P+ + LR V P R Sbjct: 221 AGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR 280 Query: 154 ---APILRPAFVPHVLQRADSALSSAAAGPRPMAL-----RPPHQAL--VGPP------- 196 AP L P + + SA S +A P L PP QA +G P Sbjct: 281 KDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHS 340 Query: 197 -LPGPPGPPMMLPPMARAPGPPLGSMAALRPPLEEPAAPRELGLGLGLGLKEKEEAVVAA 255 LP PP P+ PP PP ++ L+ P PA+P + Sbjct: 341 FLPSPPLSPLATPP---PQAPPALALPPLQAPPSPPASP----------------PLSPL 381 Query: 256 AAGLEEASAAVAVGAGGAPAGPAVIGPSLPLALAMPLPEPEPLPLPLEVVRGLLPPLRIP 315 A +A A+AV AP P PS P+ P P V PP + P Sbjct: 382 ATPSPQAPNALAVHLLQAPFSPP---PSPPVQAPFSPPASPP------VSPSATPPSQAP 432 Query: 316 ELLSLRPRPRPPRPEPPPGLMALEVPEPLGEDKKKGKPEKLKR 358 L+ P PP P P + P P P +L + Sbjct: 433 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAK 475 Score = 37.7 bits (86), Expect = 0.023 Identities = 77/288 (26%), Positives = 95/288 (32%), Gaps = 72/288 (25%) Query: 49 LGAPVPGIPTAVPAVPTVPTVPTVEAMQVPAAPVIRPIIATNTYQQVQQTLEARAAAAAT 108 L AP +P + PA P P P+ A P AP P +A Q + +A A A Sbjct: 435 LAAPPLQVPPSPPASP--PMSPS--ATPPPQAP---PPLAAPPLQLAKPPPQAPPALAT- 486 Query: 109 VVPPM--VGGPP--FVGPVGFGPG---DRSHLDSPEARE----AMFLRRAAVAPQRAPIL 157 PP+ + PP F G F P S L +P + A L + +P +P L Sbjct: 487 --PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL 544 Query: 158 R-----PAFVPHVLQRADSALSSAAAGPRPMALRPPHQALVGPPLPG------------- 199 + P P + A GP P R P L GP L G Sbjct: 545 QAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 604 Query: 200 -----PPGPPMMLPP------------MARAPGPPLGSMAALRPPLEEPAAPRELGLGLG 242 P G PP +R P PPL A PL P A G G Sbjct: 605 GYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPA---TGPGSA 661 Query: 243 LGL------KEKEEAVVAAAA-------GLEEASAAVAVGAGGAPAGP 277 GL + E A A A G AA GAG + P Sbjct: 662 DGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP 709 Score = 33.1 bits (74), Expect = 0.57 Identities = 59/223 (26%), Positives = 76/223 (34%), Gaps = 32/223 (14%) Query: 170 DSALSSAAAGPRPMALRPPHQALVGPPLPGPPGPPMMLPPMARAPGPPLGSMAALRPPLE 229 D+ A AG A R P G P PPG P PP+ A LG+ A+ Sbjct: 2 DNKRDKAKAGA---AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVG---R 55 Query: 230 EPAAPRELGLGLGLGLKEKEEAVVAAAAGLEEASAAVAVGAG--GAPAGPAVIGPSLPLA 287 +P A R G+G G + E A AG S A G G PA GP Sbjct: 56 KPLAERAGGIG-GATIPES-----APRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPG 109 Query: 288 LAMPLPEPEPL-------PLPLEVVRGLL--PPLRIPELLSLRPRPRPPRPEPPPGLMA- 337 A P PL V RG P R R P P P MA Sbjct: 110 RASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMAR 169 Query: 338 --------LEVPEPLGEDKKKGKPEKLKRCIRTAAGSSWEDPS 372 + +P P + + E ++ + +A+ S +PS Sbjct: 170 RSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPS 212 >gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo sapiens] Length = 631 Score = 62.0 bits (149), Expect = 1e-09 Identities = 34/95 (35%), Positives = 59/95 (62%), Gaps = 2/95 (2%) Query: 383 IFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREM 442 ++ + G EV+D+ L FS+F L KV+RD GK+KG+GFVS++ D +A+ EM Sbjct: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVEEM 251 Query: 443 NGKYVGSRPIKLRKSMWK-DRNLDVVRKKQKEKKK 476 NGK + + I + ++ K +R ++ RK ++ K++ Sbjct: 252 NGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQE 286 Score = 58.5 bits (140), Expect = 1e-08 Identities = 28/79 (35%), Positives = 50/79 (63%), Gaps = 2/79 (2%) Query: 383 IFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREM 442 ++ +L + ++D+ L + FS F S AKV+ + G++KG+GFV F P + +A+ EM Sbjct: 296 LYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEM 353 Query: 443 NGKYVGSRPIKLRKSMWKD 461 NG+ VGS+P+ + + K+ Sbjct: 354 NGRIVGSKPLYVALAQRKE 372 Score = 53.1 bits (126), Expect = 5e-07 Identities = 27/81 (33%), Positives = 46/81 (56%), Gaps = 3/81 (3%) Query: 383 IFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREM 442 ++ GDL ++V + +L FS L +V RD T ++ GY +V+F+ P+D RA+ M Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72 Query: 443 NGKYVGSRPIKLRKSMWKDRN 463 N + +PI++ MW R+ Sbjct: 73 NFDVIKGKPIRI---MWSQRD 90 Score = 41.6 bits (96), Expect = 0.002 Identities = 31/106 (29%), Positives = 50/106 (47%), Gaps = 12/106 (11%) Query: 347 DKKKGKPEKLKRCIRTAAGSSWEDPSLLEWDADDFRIFCGDLGNEVNDDILARAFSRFPS 406 D KGKP ++ S DPSL + + +F +L +++ L FS F + Sbjct: 75 DVIKGKPIRIMW--------SQRDPSLRKSGVGN--VFIKNLDKSIDNKALYDTFSAFGN 124 Query: 407 FLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREMNGKYVGSRPI 452 L KV+ D+ +KGY FV F+ +A+ +MNG + R + Sbjct: 125 ILSCKVVCDENG--SKGYAFVHFETQEAADKAIEKMNGMLLNDRKV 168 >gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo sapiens] Length = 644 Score = 62.0 bits (149), Expect = 1e-09 Identities = 34/95 (35%), Positives = 59/95 (62%), Gaps = 2/95 (2%) Query: 383 IFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREM 442 ++ + G EV+D+ L FS+F L KV+RD GK+KG+GFVS++ D +A+ EM Sbjct: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVEEM 251 Query: 443 NGKYVGSRPIKLRKSMWK-DRNLDVVRKKQKEKKK 476 NGK + + I + ++ K +R ++ RK ++ K++ Sbjct: 252 NGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQE 286 Score = 58.5 bits (140), Expect = 1e-08 Identities = 28/79 (35%), Positives = 50/79 (63%), Gaps = 2/79 (2%) Query: 383 IFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREM 442 ++ +L + ++D+ L + FS F S AKV+ + G++KG+GFV F P + +A+ EM Sbjct: 296 LYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEM 353 Query: 443 NGKYVGSRPIKLRKSMWKD 461 NG+ VGS+P+ + + K+ Sbjct: 354 NGRIVGSKPLYVALAQRKE 372 Score = 53.1 bits (126), Expect = 5e-07 Identities = 27/81 (33%), Positives = 46/81 (56%), Gaps = 3/81 (3%) Query: 383 IFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREM 442 ++ GDL ++V + +L FS L +V RD T ++ GY +V+F+ P+D RA+ M Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72 Query: 443 NGKYVGSRPIKLRKSMWKDRN 463 N + +PI++ MW R+ Sbjct: 73 NFDVIKGKPIRI---MWSQRD 90 Score = 41.6 bits (96), Expect = 0.002 Identities = 31/106 (29%), Positives = 50/106 (47%), Gaps = 12/106 (11%) Query: 347 DKKKGKPEKLKRCIRTAAGSSWEDPSLLEWDADDFRIFCGDLGNEVNDDILARAFSRFPS 406 D KGKP ++ S DPSL + + +F +L +++ L FS F + Sbjct: 75 DVIKGKPIRIMW--------SQRDPSLRKSGVGN--VFIKNLDKSIDNKALYDTFSAFGN 124 Query: 407 FLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREMNGKYVGSRPI 452 L KV+ D+ +KGY FV F+ +A+ +MNG + R + Sbjct: 125 ILSCKVVCDENG--SKGYAFVHFETQEAADKAIEKMNGMLLNDRKV 168 >gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo sapiens] Length = 660 Score = 62.0 bits (149), Expect = 1e-09 Identities = 34/95 (35%), Positives = 59/95 (62%), Gaps = 2/95 (2%) Query: 383 IFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREM 442 ++ + G EV+D+ L FS+F L KV+RD GK+KG+GFVS++ D +A+ EM Sbjct: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVEEM 251 Query: 443 NGKYVGSRPIKLRKSMWK-DRNLDVVRKKQKEKKK 476 NGK + + I + ++ K +R ++ RK ++ K++ Sbjct: 252 NGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQE 286 Score = 58.5 bits (140), Expect = 1e-08 Identities = 28/79 (35%), Positives = 50/79 (63%), Gaps = 2/79 (2%) Query: 383 IFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREM 442 ++ +L + ++D+ L + FS F S AKV+ + G++KG+GFV F P + +A+ EM Sbjct: 296 LYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLED--GRSKGFGFVCFSSPEEATKAVTEM 353 Query: 443 NGKYVGSRPIKLRKSMWKD 461 NG+ VGS+P+ + + K+ Sbjct: 354 NGRIVGSKPLYVALAQRKE 372 Score = 53.1 bits (126), Expect = 5e-07 Identities = 27/81 (33%), Positives = 46/81 (56%), Gaps = 3/81 (3%) Query: 383 IFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREM 442 ++ GDL ++V + +L FS L +V RD T ++ GY +V+F+ P+D RA+ M Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72 Query: 443 NGKYVGSRPIKLRKSMWKDRN 463 N + +PI++ MW R+ Sbjct: 73 NFDVIKGKPIRI---MWSQRD 90 Score = 41.6 bits (96), Expect = 0.002 Identities = 31/106 (29%), Positives = 50/106 (47%), Gaps = 12/106 (11%) Query: 347 DKKKGKPEKLKRCIRTAAGSSWEDPSLLEWDADDFRIFCGDLGNEVNDDILARAFSRFPS 406 D KGKP ++ S DPSL + + +F +L +++ L FS F + Sbjct: 75 DVIKGKPIRIMW--------SQRDPSLRKSGVGN--VFIKNLDKSIDNKALYDTFSAFGN 124 Query: 407 FLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREMNGKYVGSRPI 452 L KV+ D+ +KGY FV F+ +A+ +MNG + R + Sbjct: 125 ILSCKVVCDENG--SKGYAFVHFETQEAADKAIEKMNGMLLNDRKV 168 >gi|149773456 hypothetical protein LOC643314 [Homo sapiens] Length = 1427 Score = 61.2 bits (147), Expect = 2e-09 Identities = 104/385 (27%), Positives = 132/385 (34%), Gaps = 65/385 (16%) Query: 15 GPVVPGPGAGIPGKSGEERLKEMEAEMALFEQEVLGAPVPGIPTAVPAVPTVPT--VPTV 72 GPV P P + A + + E +P +PT P PT P VPT Sbjct: 973 GPVTPATTVHAPEEPDT-------AAVRVSTPEEPASPAAAVPT--PEEPTSPAAAVPTP 1023 Query: 73 EAMQVPAAPVIRPIIATNTYQQVQQTLEARAAAAATVVPPMVGGPPFVGPVGFGP-GDRS 131 E PAA V P T+ V E + AAA P P P P + Sbjct: 1024 EEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA 1083 Query: 132 HLDSPEAREAMFLRRAAVAPQRAPILRPAFVPHVLQRADSALSSAAAGPRPMALRPPHQA 191 + +PE + AAV P A VP + S AAA P P P A Sbjct: 1084 AVPTPEEPTS---PAAAVPTPEEPTSPAAAVP----TPEEPASPAAAVPTPEEPASPAAA 1136 Query: 192 LVGPPLPGPPGPPMMLP------------------PMARAPGP-PLGSMAALRPPLEEPA 232 + P P P P + P P A P P S AA+ LEEP Sbjct: 1137 VPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPT 1196 Query: 233 APR---ELGLGLGLGLKEKEEAVVAAAAGLEEASAAVAVGAGGAPAGPAVIGPSL----- 284 +P + L+E + E AS A AV P PA P+L Sbjct: 1197 SPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTS 1256 Query: 285 -------PLALAMP---LPEPEPLPLPLEVVRGLLPP------LRIPELLSLRPRPRPPR 328 P L+ P +P PE P V L P + PE+ ++ P P Sbjct: 1257 SAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAI-PAASVPT 1315 Query: 329 PEPPPGLMALEVPEPLGEDKKKGKP 353 PE P + A VP P+ E G P Sbjct: 1316 PE-VPAIPAAAVP-PMEEVSPIGVP 1338 Score = 48.5 bits (114), Expect = 1e-05 Identities = 78/285 (27%), Positives = 108/285 (37%), Gaps = 37/285 (12%) Query: 2 AGAGPAPGLPGAGGPVVPGPGA-GIPGKSGEERLKEMEAEMALFEQEVLGAPVPGIPTAV 60 A A P P P + VP P P + + A+ E P P +PT Sbjct: 1095 AAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPE 1154 Query: 61 PAVPTVPTVPTVEAMQVPAAPVIRPIIATNTYQQVQQTLEARAAAAATVVPP--MVGG-P 117 + VPT E PAA V P + ++ V TLE + AA+V P MV Sbjct: 1155 ESASAAVAVPTPEESASPAAAVPTP-AESASFAAVVATLEEPTSPAASVPTPAAMVATLE 1213 Query: 118 PFVGPVGFGPGDRSHLDSPEAREAMFLRRAAVAPQRAPILRPAFVPHVLQRADSAL---- 173 F P P + E L AAV+ P A VP + + SA Sbjct: 1214 EFTSPAA---------SVPTSEEPASL-AAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLT 1263 Query: 174 -----SSAAAGPRPMALRPPHQAL-----VGPPLPGPPGPPMMLPPMARAPGPPLGSM-A 222 S AA+ P P P A+ P P P + P A P P + ++ A Sbjct: 1264 PEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPA 1323 Query: 223 ALRPPLEEPAAPRELGLGLGLGLKEKEEAVVAAAAG---LEEASA 264 A PP+EE + +G+ LG+ ++V + G LEEAS+ Sbjct: 1324 AAVPPMEEVS---PIGVPF-LGVSAHTDSVPISEEGTPVLEEASS 1364 >gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens] Length = 1711 Score = 60.8 bits (146), Expect = 3e-09 Identities = 96/334 (28%), Positives = 131/334 (39%), Gaps = 33/334 (9%) Query: 56 IPTAVPA-VPTVPTVPTVEAMQVPA-APVIRPIIATNTYQQVQQTLEARA---AAAATVV 110 +P +VPA VP VP A VPA +P + P+ A TL + + + +A+V+ Sbjct: 223 VPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVL 282 Query: 111 PPMVGGPPFVGPVGFGPGDRSHLDSPEAREAMFLRRAAVAPQRAPILRPAFVPHVLQRAD 170 P+ P GPV + L P + + L +A V P AP L A VP Sbjct: 283 VPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPS-APTLVLAPVP------T 335 Query: 171 SALSSAAAGPRPMALRPPHQALVGP-PLPGPPGPPMMLPPMARAPGP-----PLGSMAAL 224 L+ A P A PP + P P GPP P ++P A P P P+ + A Sbjct: 336 PVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPT 395 Query: 225 RPPLEEPAA-PRELGLGLGLGLKEKEEAVVAAAAGLEEASAAVAVGAGGAPAGPAVIGPS 283 P PAA P + L V AA +A A V P V+ PS Sbjct: 396 PMPAATPAAIPTSAPIPASFSLSR----VCFPAA---QAPAMQKVPLSFQPG--TVLTPS 446 Query: 284 LPLALAMPLPEPEPLPL-PLEVVRGLLPPLRIPELLS-LRPRPRP---PRPEPPPGLMAL 338 PL P +PL + L G+ L +P L S L+ R P PE A Sbjct: 447 QPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAF 506 Query: 339 EVPEPLGEDKKKGKPEKLKRCIRTAAGSSWEDPS 372 V PL D K E + + +GS+ P+ Sbjct: 507 SVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPA 540 Score = 41.2 bits (95), Expect = 0.002 Identities = 55/209 (26%), Positives = 74/209 (35%), Gaps = 38/209 (18%) Query: 150 APQRAPILRPA----FVPHVLQRADSALSSAAAGPRPMALRPPHQALVGPPLPGPPGPPM 205 +P API PA VPH + A S P P+ PH LV P+ Sbjct: 197 SPLPAPICPPAPGSASVPHSVPDAFQVPLSV---PAPV----PHSGLV----------PV 239 Query: 206 MLPPMARAPGPPLGSMAALRPPLEEPAAPRELGLGLGLGLKEKEEAVVAAAAGLE----- 260 + AP PPL + AL P P+ P + L + V A+A Sbjct: 240 QVATSVPAPSPPLAPVPALAPA--PPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPL 297 Query: 261 --EASAAVAVGAGGAPAG--PAVIGPSLPLALAMPLPEPEPLPLPLEVVRGLLPPLRIPE 316 A A ++V P A + PS P + P+P P P+P P +P Sbjct: 298 SAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVP- 356 Query: 317 LLSLRPRPRPPR-PEPPPGLMALEVPEPL 344 P P P P P L+ P P+ Sbjct: 357 ----MPTPTPSSGPPSTPTLIPAFAPTPV 381 Score = 35.4 bits (80), Expect = 0.12 Identities = 55/204 (26%), Positives = 71/204 (34%), Gaps = 37/204 (18%) Query: 49 LGAPVPGIPTAVPAVPTVPTVPTVEAMQVPAAPVIRPIIATNTYQQVQQTLEARAAAAAT 108 L PV P A+ P P+ PT+ VP PV+ P+ A+ AA A Sbjct: 305 LSVPVSAPPLALIQAPVPPSAPTLVLAPVP-TPVLAPMPASTP-----------PAAPAP 352 Query: 109 VVPPMVGGPPFVGPVGFGPGDRSHLDSPEAREAMFLRRAAVAPQRAPILRPAFVPHVLQR 168 PM P GP S F AP API PA P + Sbjct: 353 PSVPMPTPTPSSGP-----------PSTPTLIPAFAPTPVPAPTPAPIFTPAPTP-MPAA 400 Query: 169 ADSALSSAAAGPRPMALR----PPHQ--ALVGPPLPGPPGPPMM-LPPMARAPGPPLGSM 221 +A+ ++A P +L P Q A+ PL PG + P+ P P G Sbjct: 401 TPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQ- 459 Query: 222 AALRPPLEEPAAPRELGLGLGLGL 245 PL P LG+ L L Sbjct: 460 -----PLSVATLPTTLGVSSTLTL 478 >gi|242117971 RNA binding motif protein, X-linked-like 1 [Homo sapiens] Length = 390 Score = 60.5 bits (145), Expect = 3e-09 Identities = 25/76 (32%), Positives = 47/76 (61%) Query: 382 RIFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMRE 441 ++F G L E N+ L F ++ ++ +I+D+ T K++G+ FV+F+ P+D A R+ Sbjct: 9 KLFIGGLNTETNEKALETVFGKYGRIVEVLLIKDRETNKSRGFAFVTFESPADAKDAARD 68 Query: 442 MNGKYVGSRPIKLRKS 457 MNGK + + IK+ ++ Sbjct: 69 MNGKSLDGKAIKVEQA 84 >gi|21361809 RNA binding motif protein, X-linked-like 1 [Homo sapiens] Length = 390 Score = 60.5 bits (145), Expect = 3e-09 Identities = 25/76 (32%), Positives = 47/76 (61%) Query: 382 RIFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMRE 441 ++F G L E N+ L F ++ ++ +I+D+ T K++G+ FV+F+ P+D A R+ Sbjct: 9 KLFIGGLNTETNEKALETVFGKYGRIVEVLLIKDRETNKSRGFAFVTFESPADAKDAARD 68 Query: 442 MNGKYVGSRPIKLRKS 457 MNGK + + IK+ ++ Sbjct: 69 MNGKSLDGKAIKVEQA 84 >gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] Length = 538 Score = 60.1 bits (144), Expect = 4e-09 Identities = 61/213 (28%), Positives = 79/213 (37%), Gaps = 46/213 (21%) Query: 130 RSHLDSPEAREAMFLRRAAVAPQRAPILRPAFVPHVLQRADSALSSAAAGPRPMALRPPH 189 R H PE A + + QRA +LR ++ + R + + G P A PP Sbjct: 60 RRHGPEPERTRAELEK---LIQQRA-VLRVSYKGSISYRNAARVQPPRRGATPPA--PPR 113 Query: 190 Q---------ALVGPPLPGPPGPPMMLPPMARAPGPPLGSMAALRPPLEEPAAPRELGLG 240 A PP P PP PP + A A P + AA PP PA P Sbjct: 114 APRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQP------ 167 Query: 241 LGLGLKEKEEAVVAAAAGLEEASAAVAVGAGGAPAGPAVIGPSLPLALAMPLPEPEPLPL 300 G + + A +AA A AVA PAGP P A PLP P P Sbjct: 168 ---GPRAQRAAPLAAPPPAPAAPPAVA-----PPAGPRRAPPPAVAAREPPLPPPPQPPA 219 Query: 301 PLEVVRGLLPPLRIPELLSLRPRPRPPRPEPPP 333 P + + +P PP+P+PPP Sbjct: 220 PPQ-----------------QQQPPPPQPQPPP 235 Score = 58.9 bits (141), Expect = 1e-08 Identities = 59/189 (31%), Positives = 69/189 (36%), Gaps = 37/189 (19%) Query: 191 ALVGPPLPG--PPGPPMMLPPMARAP-GPPLGSMAALRPPLEEPAAPRELGLGLGLGLKE 247 A V PP G PP PP RAP G P + AA PP P P Sbjct: 97 ARVQPPRRGATPPAPP-------RAPRGAPAAAAAAAPPPTPAPPPP------------- 136 Query: 248 KEEAVVAAAAGLEEASAAVAVGAGGAPAGPAVIGPSLPLALAMPLPEPEPLPLPLEVVRG 307 A VAAAA AA A GPA GP A PL P P P V Sbjct: 137 --PAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAA--PLAAPPPAPAAPPAVAP 192 Query: 308 LLPPLRI-PELLSLRPRPRPPRPEPPPGLMALEVPEPLGEDKKKG---------KPEKLK 357 P R P ++ R P PP P+PP + P P + +G +P L+ Sbjct: 193 PAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLR 252 Query: 358 RCIRTAAGS 366 +R GS Sbjct: 253 EVVRYLGGS 261 Score = 51.6 bits (122), Expect = 2e-06 Identities = 54/169 (31%), Positives = 57/169 (33%), Gaps = 57/169 (33%) Query: 50 GAPVPGIPTAVPAVPTVPTVPTVEAMQVPA-APVIRPIIATNTYQQVQQTLEARAAAAAT 108 GAP A P P P P A PA AP RAAAAA Sbjct: 117 GAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAP--------------------RAAAAAA 156 Query: 109 VVPPMVGGPPFVGPVGFGPGDRSHLDSPEAREAMFLRRAAVAPQRAPILRPAFVPHVLQR 168 PP G PG R+ +P A AP AP PA P Sbjct: 157 TAPPSPGPAQ--------PGPRAQRAAPLA-----------APPPAPAAPPAVAP----- 192 Query: 169 ADSALSSAAAGPRPMALRPPHQALVGPPLPGPPGPPMMLPPMARAPGPP 217 AGPR PP A PPLP PP PP PP + P PP Sbjct: 193 --------PAGPR--RAPPPAVAAREPPLPPPPQPP--APPQQQQPPPP 229 Score = 50.1 bits (118), Expect = 5e-06 Identities = 56/185 (30%), Positives = 60/185 (32%), Gaps = 58/185 (31%) Query: 54 PGIPTAVPAVPTVPTVPTVEAMQVPAAPVIRPIIATNTYQQVQQTLEARAAAAATVVPPM 113 P P PA P A P APV A RAAAAA PP Sbjct: 112 PRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPAR----------APRAAAAAATAPPS 161 Query: 114 VGGPPFVGPVGFGPGDRSHLDSPEAREAMFLRRAAVAPQRAPILRPAFVPHVLQRADSAL 173 G PG R+ +P A AP AP PA P Sbjct: 162 PGPAQ--------PGPRAQRAAPLA-----------APPPAPAAPPAVAP---------- 192 Query: 174 SSAAAGPRPMALRPPHQALVGPPLPGPPGPPMMLPPMARAPGPPLGSMAALRPPLEEPAA 233 AGPR PP A PPLP PP PP PP + P PP +P Sbjct: 193 ---PAGPRRAP--PPAVAAREPPLPPPPQPPA--PPQQQQPPPP------------QPQP 233 Query: 234 PRELG 238 P E G Sbjct: 234 PPEGG 238 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 59.7 bits (143), Expect = 6e-09 Identities = 93/360 (25%), Positives = 127/360 (35%), Gaps = 40/360 (11%) Query: 16 PVVPGP---GAGIPGKSGEERLKEMEAEMALFEQEVLGAPVPGIPTAVPAVPTVPTVPTV 72 P PGP A GK+G + ++EA + +E+ P P P PT P Sbjct: 406 PKEPGPLQCEAKPLGKAGVQLEPQLEAPL---NEEMPLLPPPEESPLSPPPEESPTSPPP 462 Query: 73 EAMQVPAAPVIRPIIATNTYQQVQQTLEARAAAAATVVPPMVGGPPFVGPVGFGPGDRSH 132 EA ++ P P + + LE + P+ PP P F P + S Sbjct: 463 EASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPL-SPPPESSP--FSPLEESP 519 Query: 133 LDSPE-AREAMFLRRAAVAPQRAPILRPAFVPHVLQRADSALSSAAAGPRPMALR---PP 188 L PE + + L P A L P F L L ++ P P A R PP Sbjct: 520 LSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTS---PPPEASRLSPPP 576 Query: 189 HQALVGPPLPGPPGPPMMLPPMARAPGPPLGSMAALRPPLEEPAAPRELGLGLGLGLKEK 248 ++ + PP P PM PP A PP PP E P +P L ++ Sbjct: 577 EESPMSPP---PEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDS 633 Query: 249 ------EEAVVAAAAGLEEASAAVAVGAGGAPAGPAVIGPSLPLALAMPLPEPEPLPLPL 302 EE+ ++ + S V P + + P PE P P Sbjct: 634 PMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPP---------PEESPTSPPP 684 Query: 303 EVVRGLLPPLRIPELLSLRPRPRPPRPEPPPGLMALEVPEPLGEDKKKGKPEKLKRCIRT 362 E R PP P S P P P P LM+L PL E PE+ + C R+ Sbjct: 685 EASRLSPPPEDSP--TSPPPEDSPASPPPEDSLMSL----PLEESPLLPLPEEPQLCPRS 738 Score = 44.3 bits (103), Expect = 2e-04 Identities = 80/346 (23%), Positives = 114/346 (32%), Gaps = 90/346 (26%) Query: 3 GAGPAPGLPGAGGPVVPGPGAGIPGKSGEERLKEMEAEMALFEQEVLGAPVPGIPTAVPA 62 GA P + GA PGAG PG+ PG P P+ Sbjct: 2204 GAPAQPPMLGASSR----PGAGQPGE--------------------FHTTPPGTPRHQPS 2239 Query: 63 VPTV---PTVPTVEAMQVPAAPVI------RPIIATNTYQQVQQTLEARAAAAATVVPPM 113 P P P+++ + VP +P + P+++ + + ++ LE + P Sbjct: 2240 TPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSY 2299 Query: 114 VGGPPFVGPVGFGPGDRSHLDSPEAREAMFLRRAAVAPQRAPILRPAFVPHVLQRADSAL 173 GPP +G V P +HL E + + A + P RA + P Sbjct: 2300 --GPPNLGFVD-SPSSGTHLGGLELKTPDVFK-APLTP-RASQVEP-------------- 2340 Query: 174 SSAAAGPRPMALRPPHQALVGPP-------LPGPPGPPMMLPPMARAPGPPLGSMAALRP 226 S G RP PP QAL P PG P PP+ P PP P Sbjct: 2341 QSPGLGLRPQE-PPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALP 2399 Query: 227 PLEEPAAPRELGLGLGLGLKEKEEAVVAAAAGLEEASAAVAVGAGGAPAGPAVIGPSLPL 286 P P+ P + V A+ + +S + P PS P+ Sbjct: 2400 PRSLPSDP---------------FSRVPASPQSQSSSQSPLT---PRPLSAEAFCPS-PV 2440 Query: 287 ALAMPLPEPEPLPLPLEVVRGLLPPLRIPELLSLRPRPRPPRPEPP 332 P+P PP R P +PPRP+PP Sbjct: 2441 TPRFQSPDPYS-----------RPPSRPQSRDPFAPLHKPPRPQPP 2475 Score = 35.8 bits (81), Expect = 0.088 Identities = 74/351 (21%), Positives = 116/351 (33%), Gaps = 60/351 (17%) Query: 44 FEQEVLGAPVPGIPTAVPAVPTVPTVPTVEAMQVPA---APVIRPIIATNTYQQVQQTLE 100 FE+ L P +PT+ P + + P E+ P +P+ P A+ + +++ Sbjct: 549 FEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPL 608 Query: 101 ARAAAAATVVPP----MVGGPPFVGPVGFGPGDRSHLDSPEAREAMFL---RRAAVAPQR 153 + + + PP + PP P+ P + PE L R + P+ Sbjct: 609 SPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEE 668 Query: 154 APILRPAFVPHVLQRADSALSSAAAGPRPMALR---PPHQALVGPPLPGPPGPPMMLPPM 210 +P+ P + P P A R PP + PP P P PP Sbjct: 669 SPLSPPP-------------EESPTSPPPEASRLSPPPEDSPTSPP---PEDSPASPPPE 712 Query: 211 ARAPGPPLGSMAALRPPLEEPAAPRELGLGLGLGLKE------KEEAVVAAAA-----GL 259 PL L P E PR G L +E EE ++ A Sbjct: 713 DSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSP 772 Query: 260 EEASAAVAVGAGGAPAGPAVIGPSLPLALAMPLPEPEPLPLPLEVVRGLLPPLRIPELLS 319 + + P GP L P+PE L L + L P +PE Sbjct: 773 QPEEPCLCAVPEEPHLSPQAEGPHLS-------PQPEELHLSPQTEEPHLSP--VPEEPC 823 Query: 320 LRPRPRPPR-----------PEPPPGLMALEVPEPLGEDKKKGKPEKLKRC 359 L P+P P P ++ E+ +P + + PE+ +C Sbjct: 824 LSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQC 874 Score = 33.9 bits (76), Expect = 0.34 Identities = 59/221 (26%), Positives = 76/221 (34%), Gaps = 55/221 (24%) Query: 135 SPEAREAMFLRRAAVAPQRAPILRPAF-------VPHVLQRADSALSSAA-AGPRPMALR 186 S ++ M L R A +AP L+ A + V ++A+S ++ G Sbjct: 2039 SSRCKQIMKLWRKVPAADKAPYLQKAKDNRAAHRINKVQKQAESQINKQTKVGDIARKTD 2098 Query: 187 PPHQALVGPPLPGPPGPPMMLPPMARAPGPPLGSMAALRPPLEEPAAPRELGLGLGLGLK 246 P L PP PG G P P A AP +GS P P Sbjct: 2099 RPALHLRIPPQPGALGSP----PPAAAPTIFIGS----------PTTP------------ 2132 Query: 247 EKEEAVVAAAAGLEEASAAVAVGAGGAPAGPAVIGPSLPLALAMPLPEPEPLPLPLEVVR 306 AGL + A G PAG +V GP P L + LP P +P + Sbjct: 2133 ----------AGLSTS----ADGFLKPPAG-SVPGPDSPGELFLKLPPQVPAQVPSQDPF 2177 Query: 307 GLLPPLRIPELLSLRPRPRPPRPEP------PPGLMALEVP 341 GL P + P PP P P PP L A P Sbjct: 2178 GLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRP 2218 Score = 33.1 bits (74), Expect = 0.57 Identities = 39/137 (28%), Positives = 51/137 (37%), Gaps = 25/137 (18%) Query: 118 PFVG-PVGFGPGDRSHLDSPEAREAMFLRRAAVAPQRAPI--LRPAFVPHVLQRADSALS 174 P +G P PG+ PE +++PQ P L P P + A ALS Sbjct: 893 PLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALS 952 Query: 175 SAAAGPRPMALR---PPHQALVGPPLPGP-------------PGPPMMLPPMARAPGPPL 218 P + P L P L P P PPM+LPP +PG P+ Sbjct: 953 PLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPP---SPGSPV 1009 Query: 219 GSMAALRPPLEEPAAPR 235 G + P L EP P+ Sbjct: 1010 GPAS---PILMEPLPPQ 1023 Score = 33.1 bits (74), Expect = 0.57 Identities = 33/117 (28%), Positives = 47/117 (40%), Gaps = 24/117 (20%) Query: 210 MARAPGPPLGSMAALRPPLEEPAAPRELGLGLGLGLKEKEEAVVAAAAGLEEASA----- 264 +A PG P PL+ ++P LG L L KE+ A ++ E + Sbjct: 3995 VALGPGMPA-------KPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGG 4047 Query: 265 --AVAVGAGGAPAGPAVIGPSLP----LALAMPLPEPEPLPLPLEVVRGLLPPLRIP 315 A+ P + PSL L L P P+P+P L L+ PPLR+P Sbjct: 4048 PLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQ------PPLRLP 4098 Score = 31.6 bits (70), Expect = 1.7 Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 4/62 (6%) Query: 152 QRAPILRPAFVPHVLQRADSALSSAAAGPRPMALRPP--HQALVGPPL-PGPP-GPPMML 207 Q+ +L + Q+ ++ A GP+P L PP HQ L+ L P PP GP ML Sbjct: 3743 QQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGML 3802 Query: 208 PP 209 P Sbjct: 3803 GP 3804 Score = 31.6 bits (70), Expect = 1.7 Identities = 18/43 (41%), Positives = 23/43 (53%), Gaps = 3/43 (6%) Query: 198 PGPPGPPMM-LPPMARAPGPPLGSMAALRPPL--EEPAAPREL 237 P P GPP + PP A + GP LG + PP +EP P +L Sbjct: 4281 PRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQL 4323 Score = 31.2 bits (69), Expect = 2.2 Identities = 64/229 (27%), Positives = 83/229 (36%), Gaps = 38/229 (16%) Query: 118 PFVGPVGFGPGDRSHLDSPEAREAMFLRRAAVAPQRAPILR-PAFVPHVLQRADSALSSA 176 P + P GP HL SP+ E + L P +P+ P P Q +S LS Sbjct: 786 PHLSPQAEGP----HL-SPQPEE-LHLSPQTEEPHLSPVPEEPCLSP---QPEESHLSPQ 836 Query: 177 AAGPRPMALRP-PHQALVGPPLPGPPGPPMMLPPMARAPGPPLGSMAALRPPLEEPAAPR 235 + P L P P ++ + P L PP P P P L PP EP+ Sbjct: 837 SEEP---CLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSP 893 Query: 236 ELGLGLGLGLKEKEEAVVAAAAGLEEASAAVAVGAGGAPAGPAVIGPSLPLALAMPLPEP 295 LG L E E ++ EE +P+G + P L MP P Sbjct: 894 LLG---EPALSEPGEPPLSPLP--EELPL--------SPSGEPSLSPQL-----MP---P 932 Query: 296 EPLPLPLE-VVRGLLPPLRIP--ELLSLRPRPRPPRPEPPPGLMALEVP 341 +PLP PL ++ PP P EL PE P LE P Sbjct: 933 DPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETP 981 Score = 30.4 bits (67), Expect = 3.7 Identities = 36/124 (29%), Positives = 49/124 (39%), Gaps = 23/124 (18%) Query: 226 PPLEEPAAPRELGLGLGLGLKEKEEAVVAAAAG-LEEASAAVAVGAGGAPAGPAVIGPSL 284 PP +EP GL LG + + G L+E +GAG P GP + P+ Sbjct: 4241 PPYQEPGTQTSPLQGL-LGCQPQLGGFPGPQTGPLQE------LGAGPRPQGPPRL-PAP 4292 Query: 285 PLALAM--------PLPEPEPLPLPLEVVRGLLPPLRIPELLSL------RPRPRPPRPE 330 P AL+ P P P P + P ++P L P+P+ P E Sbjct: 4293 PGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLE 4352 Query: 331 PPPG 334 PPPG Sbjct: 4353 PPPG 4356 Score = 29.6 bits (65), Expect = 6.3 Identities = 37/126 (29%), Positives = 44/126 (34%), Gaps = 24/126 (19%) Query: 190 QALVGPPLPGPPGPPMMLPPMARAPGPPLGS-MAALRPPLE------------------E 230 +AL+ PGP GP PP A A P L S + ++P +E E Sbjct: 3083 EALLRGVEPGPLGPEERPPPAADASEPRLASVLPEVKPKVEEGGRHPSPCQFTIATPKVE 3142 Query: 231 PA-APRELGLGLGLGLKEKEEAVVAAAAGLEEASAAVAVGAGGAPAGPAVIGPSLPLALA 289 PA A LGLGL G G +S A A G GP L Sbjct: 3143 PAPAANSLGLGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATG----GPPAHLLTP 3198 Query: 290 MPLPEP 295 PL P Sbjct: 3199 SPLSGP 3204 Score = 29.3 bits (64), Expect = 8.3 Identities = 50/204 (24%), Positives = 65/204 (31%), Gaps = 39/204 (19%) Query: 163 PHVLQRADSALSSAAAGPRPMALRPPHQALVGPPLPGPPGPPMMLPPMARAPGPPLGSMA 222 P V + S A P+ R P PP P P G P P + + P G Sbjct: 2165 PQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPG 2224 Query: 223 ALR----------------------PPLEEPAAPRELGLGLGLGLKEKEEAVVAAAAGLE 260 P L+ A P G+G G K E + G Sbjct: 2225 EFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVG---GGKASEPLLSPPPFGES 2281 Query: 261 EASAAV---AVGAGGAPAGPAVIG----PSLPLAL-AMPLPEPEPLPLPLEVVRGLLPPL 312 + V +GA GP +G PS L + L P+ PL + P Sbjct: 2282 RKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEP- 2340 Query: 313 RIPELLSLRPRPRPP----RPEPP 332 + P L LRP+ PP P PP Sbjct: 2341 QSPG-LGLRPQEPPPAQALAPSPP 2363 >gi|146219843 Snf2-related CBP activator protein [Homo sapiens] Length = 3230 Score = 59.7 bits (143), Expect = 6e-09 Identities = 85/339 (25%), Positives = 123/339 (36%), Gaps = 54/339 (15%) Query: 30 GEERLKEMEAEMALFEQEVLGAPVPGIPTAVPAVP--TVPTVPTVEAMQVPAAPVIRPII 87 G+ L A +AL + AP PG PT V +P T T P + +P A P Sbjct: 1246 GQHHLISQPAHVALIQAV---APTPG-PTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPT 1301 Query: 88 ATNTYQQVQQTLEARAAAAATVVPPMVGGP--PFVG-PVGFGPGDRSHLDSPEAREAMFL 144 N V+ + T VPP+ P P G P P R L L Sbjct: 1302 MVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNP--RPTLTPGR------L 1353 Query: 145 RRAAVAPQRAPILRPAFVPHVLQRADSA---LSSAAAGPRPMALRPPHQALVGPPLPGPP 201 + RAP+ P V +L+ S +S++A G P+ + P V LPGP Sbjct: 1354 PTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLH--VPSSLPGPA 1411 Query: 202 GPPMMLP-------PMARAPGPPLGSMAALRPPLEEPA---APRELGLGLGLGLKEKEEA 251 PM +P P++ PL S + P PA AP + + L + A Sbjct: 1412 SSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPA 1471 Query: 252 VVA-------------------AAAGLEEASAAVAVGAGGAPAGPAVIGPSLPLALAMPL 292 ++ A +G +++A+ +G AP+ + P PL LA Sbjct: 1472 LLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLA--- 1528 Query: 293 PEPEPLPLPLEVVRGLLPPLRIPELLSLRPRPRPPRPEP 331 P +P V P+ +P P P P P P Sbjct: 1529 PTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAP 1567 Score = 57.8 bits (138), Expect = 2e-08 Identities = 97/421 (23%), Positives = 147/421 (34%), Gaps = 90/421 (21%) Query: 3 GAGPAPGLPGA---GGPVVPGPGAG-IPGKSGEERLKEMEAEMALFEQEVLGAPVPGIPT 58 G AP L + G P++ P + +PG + L L +P P P Sbjct: 1508 GLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVA---PACSPVLVPASALASPFPSAPN 1564 Query: 59 AVPAVPTV--PTVPTVEAMQVPAAPVIRPIIATNTYQQVQQTLEARAAAAATVVPPMVGG 116 PA ++ P +A+ P AP+ P Q + A + A P++ Sbjct: 1565 PAPAQASLLAPASSASQALATPLAPMAAP----------QTAILAPSPAPPLAPLPVLAP 1614 Query: 117 PPFVGPVGFGPGDRSHLDSPEAREAMFLRRAAVAPQRAPILRPAFVPHVLQRADSALSSA 176 P PV + +P + L A+ P P+L P+ +L + + Sbjct: 1615 SPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPS 1674 Query: 177 AAGPRPMALRPPHQALVGPPLPG---------PPGP---------------PMMLPPMAR 212 A + +AL P +G P P GP P ++ Sbjct: 1675 PASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSL 1734 Query: 213 APGPPLGSMAALR----PPLEEPAAPRELGLGLGLGLKEKEEAVVAAAAGLEEASAAVAV 268 APGPPLG L PPL PA+P +G +A A+ A +V Sbjct: 1735 APGPPLGPTQTLSLAPAPPLA-PASP--------VGPAPAHTLTLAPASSSASLLAPASV 1785 Query: 269 GAGG-APAGPAVIGPSLPLALAM-------PLPEPEPL--------PLPLEVVRGLLPPL 312 +PA +GP+ LA+ P + L PLP+ +V L Sbjct: 1786 QTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSK 1845 Query: 313 RIPELLSLR---------------PRPRPPRPEPPPGLMALEVPEPLGEDKKKGKPEKLK 357 P+ L+LR PRPR P PP L + L E +K+ + E+L+ Sbjct: 1846 DEPDTLTLRSGPPSPPSTATSFGGPRPRRQPPPPPRSPFYL---DSLEEKRKRQRSERLE 1902 Query: 358 R 358 R Sbjct: 1903 R 1903 Score = 51.2 bits (121), Expect = 2e-06 Identities = 89/341 (26%), Positives = 117/341 (34%), Gaps = 73/341 (21%) Query: 11 PGAGGPVVPGP---GAGIPGKSGEERLKEMEAEMALFEQEVLGAPVPGIPTAVPAVPTVP 67 PGA + P + +PG + + M + L +PV +VP ++P Sbjct: 1390 PGAAPLTISSPLHVPSSLPGPAS--------SPMPIPNSSPLASPVSST-VSVPLSSSLP 1440 Query: 68 -TVPTVEAMQVPA-APVIRPIIATNTYQQVQQTLEARAAAAATVVPPMVGGPPFVGPVGF 125 +VPT + PA AP+ PI A T L V P GPP + P G Sbjct: 1441 ISVPTT--LPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGA 1498 Query: 126 GPGDRS---------HLDSPEAREAMFL----------RRAAVAPQRAPILRPAFVPHVL 166 P + L S + L + VAP +P+L PA Sbjct: 1499 SPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPA------ 1552 Query: 167 QRADSALSSAAAGPRPMALRP-PHQALVGPPLP------GPPGPPMMLPP---MARAPGP 216 SA A P P A P P QA + P P PM P +A +P P Sbjct: 1553 --------SALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAP 1604 Query: 217 PLGSMAALRPPLEEPAAPRELGLGLGLGLKEKEEAVVAAAAGLEEASAAVAVGAGGAPAG 276 PL + L P P A L + V A + S A A PA Sbjct: 1605 PLAPLPVLAP---SPGAAPVLA-------SSQTPVPVMAPSSTPGTSLA---SASPVPAP 1651 Query: 277 PAVIGPSLPLALAMPLPEPEPLPLPLEVVRGLLPPLRIPEL 317 V+ PS + +P P P PLP P L P P L Sbjct: 1652 TPVLAPSSTQTM-LPAPVPSPLPSPASTQTLALAPALAPTL 1691 Score = 38.9 bits (89), Expect = 0.010 Identities = 73/311 (23%), Positives = 100/311 (32%), Gaps = 35/311 (11%) Query: 52 PVPGIPTAVPAVPTVPTVPTVEAMQVPAAPVIRPIIATNTYQQVQQTLEARAAAAATVVP 111 P P P + P + ++ + VP P AT T A A T VP Sbjct: 1108 PTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTT-------ATATTTAVP 1160 Query: 112 PMVGGPPFVGPVGFGPGDRSHLDSPEAREAMFLRRAAVAPQRAPILRPAFVPHVLQRADS 171 P + P ++ L S E + + + A QR P Q + Sbjct: 1161 APTPAPQ---RLILSPDMQARLPSGEV---VSIGQLASLAQRPVANAGGSKPLTFQIQGN 1214 Query: 172 ALSSAAAG--------PRPMALRPPHQALVGPP--LPGPPGPPMMLPPMARAPGPPLGSM 221 L+ A PRP+ H G L P ++ +A PGP S+ Sbjct: 1215 KLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSV 1274 Query: 222 AALRPPLEEPAAPRELGLGLGLGLKEKEEAVVAAAAGLEEASAAVAVGAGGAPAGPAVIG 281 P PA GL L L + +V G+ + A G P P Sbjct: 1275 LPSSTPSTTPAPT---GLSLPLAANQVPPTMVNNT-GVVKIVVRQAPRDGLTPVPPLAPA 1330 Query: 282 PSLPLALAMPLPEPEP------LPLP-LEVVRGLLP-PLRIPELLSLRPRPRPPRPEPPP 333 P P + + P P LP P L R +P P + LL L P P P Sbjct: 1331 PRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAP 1390 Query: 334 GLMALEVPEPL 344 G L + PL Sbjct: 1391 GAAPLTISSPL 1401 Score = 38.5 bits (88), Expect = 0.014 Identities = 73/284 (25%), Positives = 92/284 (32%), Gaps = 84/284 (29%) Query: 146 RAAVAPQRAPILRPAFVPHVLQRADSALSSAAAGPRPMALRPPHQALVGPPLPGPPGP-- 203 R A P+ P PA +P ++ SA +A P P+ + P H LP PP P Sbjct: 2438 RPAPRPRPTPASAPAAIPALVPVPVSAPVPISA-PNPITILPVHI------LPSPPPPSQ 2490 Query: 204 ------PMMLPPMARAPGPPLGSMAALRPPLEEPAAPRELG----------LGLGLGLKE 247 P PP A P PP + + L P++P LG L LGL+ Sbjct: 2491 IPPCSSPACTPPPACTP-PPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRP 2549 Query: 248 KEEAVVAAAA---GLEEASAA--------------------------------------V 266 + E A A LE AS A + Sbjct: 2550 EAELCAQALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSL 2609 Query: 267 AVGAGGAPAGPAVIGPSLPLALAMP-LPEPEPLPLPLEVVRGL-LPPL------------ 312 + AG P G P + LPE E LPL + GL LPP Sbjct: 2610 TLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLE 2669 Query: 313 --RIPELLSLRPRPRPPRPEPPPGLMALEVPEPLGEDKKKGKPE 354 R E L+ P PE P L+ EV P PE Sbjct: 2670 ADRTSEELTEAKTP-TSSPEKPQELVTAEVAAPSTSSSATSSPE 2712 Score = 38.1 bits (87), Expect = 0.018 Identities = 77/334 (23%), Positives = 116/334 (34%), Gaps = 55/334 (16%) Query: 47 EVLGAPVPG-IPTAVPA---VPTVPTVPTVEAMQVPAAPVIRPIIATNTYQQVQQTLEAR 102 E+ P PG +P +PA V P P + P PV+ P + N+ Q Sbjct: 1031 ELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVLPSPL 1090 Query: 103 AAAAATVVPP-----MVGGPPFVGPVGFGPGDRSHLDSPEAREAMFLRRAAVAPQRAPIL 157 + T PP + PP PV P +P + L+ V P Sbjct: 1091 GVLSGTSRPPTPTLSLKPTPP--APVRLSP-------APPPGSSSLLKPLTVPP--GYTF 1139 Query: 158 RPAFVPHVLQRADSALSSAAAGPRPMALRPPHQALVGPPLPG--PPGPPMMLPPMARAPG 215 PA +A ++A P P P + ++ P + P G + + +A Sbjct: 1140 PPAAATTTSTTTATATTTAVPAPTP----APQRLILSPDMQARLPSGEVVSIGQLASLAQ 1195 Query: 216 PPLGSMAALRPPLEE---------PAAPRELGLGLGLGLKEKEEAVVAAAA--GLEEASA 264 P+ + +P + A R+L +G L+ +V+A L A Sbjct: 1196 RPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPA 1255 Query: 265 AVAVGAGGAPA-GPAVIGPSLPLALAMPLPEPEPLPLPLEVVRGLLPPLRIPE------L 317 VA+ AP GP P L + P P P L L + +PP + + Sbjct: 1256 HVALIQAVAPTPGPT---PVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIV 1312 Query: 318 LSLRPR-------PRPPRPEPP-PGLMALEVPEP 343 + PR P P P PP GL A+ P P Sbjct: 1313 VRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRP 1346 Score = 35.0 bits (79), Expect = 0.15 Identities = 46/180 (25%), Positives = 68/180 (37%), Gaps = 44/180 (24%) Query: 187 PPHQALVGPPLPGPPGPPMMLPPMARAPGPPL-----------------------GSMAA 223 P +++ GP P G P P + P PP G++ A Sbjct: 2791 PSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTGGGSPENGDGALLA 2850 Query: 224 LRPPLEEPAAPRELGLGLGLGLKEKEEAVVAAAAGLEEASAAVAVGA--GGAPA-GPAVI 280 + P PA R G +K + A G++EA ++ G G P GP + Sbjct: 2851 ITP----PAVKRRRGRP-----PKKNRSPADAGRGVDEAPSSTLKGKTNGADPVPGPETL 2901 Query: 281 GPSLPLALAMPLPEPEPL-PLPLEVVRGLLPPLRIPELLSLRPRPRPP--RPEPPPGLMA 337 + P+ +P P+PL P P+ LL P + R R RPP R P PG ++ Sbjct: 2902 IVADPVLEPQLIPGPQPLGPQPVHRPNPLLSP------VEKRRRGRPPKARDLPIPGTIS 2955 Score = 34.7 bits (78), Expect = 0.20 Identities = 58/264 (21%), Positives = 79/264 (29%), Gaps = 64/264 (24%) Query: 146 RAAVAPQRAPILRPAFVPHVLQRADSALSSAAAGPRPMALRPPHQALVGPPLPGPPGPPM 205 R P+ + P VP VL + +S A P A RPP L+ P P P Sbjct: 1025 RPPPGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQ 1084 Query: 206 MLP-------------------------PMARAPGPPLGSMAALRPPLEEPA-------- 232 +LP P+ +P PP GS + L+P P Sbjct: 1085 VLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAA 1144 Query: 233 --------------------APRELGLGLGLGLKEKEEAVVAAAAGLEEASAAVAVGAGG 272 AP+ L L + + VV+ A VA G Sbjct: 1145 TTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGS 1204 Query: 273 APAGPAVIGPSLPL--ALAMPLPEPEPLPLPLEVV---------RGLLPPLRIPELLSLR 321 P + G L L A L +P PL VV + P + + ++ Sbjct: 1205 KPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVA 1264 Query: 322 PRPRPPRPEPPPGLMALEVPEPLG 345 P P P P P P G Sbjct: 1265 PTPGPTPVSVLPSSTPSTTPAPTG 1288 Score = 32.3 bits (72), Expect = 0.98 Identities = 52/216 (24%), Positives = 71/216 (32%), Gaps = 39/216 (18%) Query: 165 VLQRADSALSSAAA---GPRPMALRPPHQALVGP-------PLPGPPGPPMML------- 207 + Q A AL A A GP P+++ P P PL PP M+ Sbjct: 1251 ISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVK 1310 Query: 208 --------------PPMARAPGPPLGSMAAL---RPPLEEPAAPRELGLGLGLGLKEKEE 250 PP+A AP PP + A+ RP L P LG Sbjct: 1311 IVVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPT-LGTARAPMPTPT 1369 Query: 251 AVVAAAAGLEEASAAVAVGAGGAPAGPAVIGPSL--PLALAMPLPEPEPLPLPLEVVRGL 308 V + S V+ A GA P I L P +L P P P+P + + Sbjct: 1370 LVRPLLKLVHSPSPEVSASAPGA--APLTISSPLHVPSSLPGPASSPMPIPNSSPLASPV 1427 Query: 309 LPPLRIPELLSLRPRPRPPRPEPPPGLMALEVPEPL 344 + +P SL P P + + + PL Sbjct: 1428 SSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPL 1463 Score = 29.6 bits (65), Expect = 6.3 Identities = 21/61 (34%), Positives = 28/61 (45%), Gaps = 7/61 (11%) Query: 291 PLPEPEPLPLPLEVVRGLLP-PLRIPELLSLRPRPRPP------RPEPPPGLMALEVPEP 343 P P P P P+ ++V R L P P + + + PR P RP P P L A P P Sbjct: 981 PDPPPRPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSAQPTPGP 1040 Query: 344 L 344 + Sbjct: 1041 V 1041 >gi|7706501 WW domain binding protein 11 [Homo sapiens] Length = 641 Score = 59.7 bits (143), Expect = 6e-09 Identities = 65/214 (30%), Positives = 77/214 (35%), Gaps = 49/214 (22%) Query: 148 AVAPQRAPILRPAFVPHVLQRADSALSSAAAGPRPMA-LRPPHQALVGPPLPGPPGPPMM 206 A + Q+AP P VP +A GP P LRPP GPP PPGPP Sbjct: 386 ASSQQQAP---PQSVPPSQIQAPPMPGPPPLGPPPAPPLRPP-----GPPTGLPPGPPPG 437 Query: 207 LPPMARAPGPP--LGSMAALRPPLEEPAAPRELGLGLGLGLKEKEEAVVAAAAGLEEASA 264 PP R PG P G + L PP P P G GL Sbjct: 438 APPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGL------------------- 478 Query: 265 AVAVGAGGAPAGPAVIGPSLPLALAMPLPEPEPLPLPLEVVRGLLPPLRIPELLSLRPRP 324 P GP GP P L P P P P P G++ P +P L P Sbjct: 479 ---------PPGPPPRGP--PPRLPPPAPPGIPPPRP-----GMMRPPLVPPLGPAPPGL 522 Query: 325 RPPRPEPPPGLMALE---VPEPLGEDKKKGKPEK 355 PP P P PG+++ + P +D EK Sbjct: 523 FPPAPLPNPGVLSAPPNLIQRPKADDTSAATIEK 556 Score = 52.8 bits (125), Expect = 7e-07 Identities = 44/136 (32%), Positives = 50/136 (36%), Gaps = 5/136 (3%) Query: 104 AAAATVVPPMVGGPPFVGPVGFGPGDRSHLDSPEAREAMFLRRAAVAPQRAPILRPAFVP 163 A +V P + PP GP GP L P + P P LRP +P Sbjct: 392 APPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGL---PPGPPPGAPPFLRPPGMP 448 Query: 164 HVLQRADSALSSAAAGPRPMALRPPHQALVGPPLPGPPGPPMMLPPMARAPGPPLGSMAA 223 + L RP PP PP P P GPP LPP A PG P Sbjct: 449 GLRGPLPRLLPPGPPPGRPPG-PPPGPPPGLPPGPPPRGPPPRLPPPA-PPGIPPPRPGM 506 Query: 224 LRPPLEEPAAPRELGL 239 +RPPL P P GL Sbjct: 507 MRPPLVPPLGPAPPGL 522 Score = 29.6 bits (65), Expect = 6.3 Identities = 23/67 (34%), Positives = 31/67 (46%), Gaps = 6/67 (8%) Query: 184 ALRPPHQALVGPPLPGPPGPPMMLPPMARAPGPPLGSMAALRPPLEEPAAPRELGLGLGL 243 A PP +A+ PL G P LPP + PGPP G PP R++G L L Sbjct: 172 AYGPPTRAVSILPLLGHGVP--RLPPGRKPPGPPPGP----PPPQVVQMYGRKVGFALDL 225 Query: 244 GLKEKEE 250 + ++E Sbjct: 226 PPRRRDE 232 >gi|56699409 RNA binding motif protein, X-linked [Homo sapiens] Length = 391 Score = 59.3 bits (142), Expect = 7e-09 Identities = 24/76 (31%), Positives = 47/76 (61%) Query: 382 RIFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMRE 441 ++F G L E N+ L F ++ ++ +++D+ T K++G+ FV+F+ P+D A R+ Sbjct: 9 KLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARD 68 Query: 442 MNGKYVGSRPIKLRKS 457 MNGK + + IK+ ++ Sbjct: 69 MNGKSLDGKAIKVEQA 84 >gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo sapiens] Length = 370 Score = 58.9 bits (141), Expect = 1e-08 Identities = 25/73 (34%), Positives = 48/73 (65%), Gaps = 2/73 (2%) Query: 382 RIFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMRE 441 +++ +L + ++D+ L FS F S + KV++++ G++KG+G + F P D +AM E Sbjct: 294 KLYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQEE--GQSKGFGLICFSSPEDATKAMTE 351 Query: 442 MNGKYVGSRPIKL 454 MNG+ +GS+P+ + Sbjct: 352 MNGRILGSKPLSI 364 Score = 50.1 bits (118), Expect = 5e-06 Identities = 26/81 (32%), Positives = 45/81 (55%), Gaps = 3/81 (3%) Query: 383 IFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREM 442 ++ GDL +V +D+L R FS L ++ RD+ T ++ GY +V+F +D +A+ M Sbjct: 12 LYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDTM 71 Query: 443 NGKYVGSRPIKLRKSMWKDRN 463 N + + I+L MW R+ Sbjct: 72 NFDIIKGKSIRL---MWSQRD 89 Score = 49.7 bits (117), Expect = 6e-06 Identities = 27/98 (27%), Positives = 55/98 (56%), Gaps = 1/98 (1%) Query: 383 IFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREM 442 ++ + G +++D+ L FS++ L KV+ D +GK+KG+GFVSF +A+ EM Sbjct: 192 VYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVEEM 250 Query: 443 NGKYVGSRPIKLRKSMWKDRNLDVVRKKQKEKKKLGLR 480 NG+ + + I + ++ K +++ ++ K+ +R Sbjct: 251 NGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIR 288 Score = 44.7 bits (104), Expect = 2e-04 Identities = 32/92 (34%), Positives = 48/92 (52%), Gaps = 4/92 (4%) Query: 383 IFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREM 442 +F +L +++ L FS F L +KV+ D + +KGY FV F++ S RA+ EM Sbjct: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQG--SKGYAFVHFQNQSAADRAIEEM 157 Query: 443 NGKYV-GSRPIKLRKSMWKDRNLDVVRKKQKE 473 NGK + G + R KDR + +R K E Sbjct: 158 NGKLLKGCKVFVGRFKNRKDREAE-LRSKASE 188 >gi|4502847 cold inducible RNA binding protein [Homo sapiens] Length = 172 Score = 58.5 bits (140), Expect = 1e-08 Identities = 26/77 (33%), Positives = 48/77 (62%) Query: 378 ADDFRIFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVR 437 +D+ ++F G L + N+ L + FS++ + V++D+ T +++G+GFV+F++ D Sbjct: 3 SDEGKLFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKD 62 Query: 438 AMREMNGKYVGSRPIKL 454 AM MNGK V R I++ Sbjct: 63 AMMAMNGKSVDGRQIRV 79 >gi|223890219 RNA binding motif protein, X-linked-like 3 [Homo sapiens] Length = 1067 Score = 58.2 bits (139), Expect = 2e-08 Identities = 23/77 (29%), Positives = 49/77 (63%) Query: 382 RIFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMRE 441 ++F G L + ++ L F ++ +K +++D++T K++G+ FV+F+ P+D A R+ Sbjct: 9 KLFIGGLNLKTDEKALKAEFGKYGHIIKVFLMKDRKTNKSRGFAFVTFESPADAKAAARD 68 Query: 442 MNGKYVGSRPIKLRKSM 458 MNGKY+ + I + +++ Sbjct: 69 MNGKYLDGKAIMVAQTI 85 >gi|27436925 synoviolin 1 isoform a [Homo sapiens] Length = 616 Score = 56.6 bits (135), Expect = 5e-08 Identities = 62/194 (31%), Positives = 80/194 (41%), Gaps = 30/194 (15%) Query: 131 SHLDSPEAREAMFLRRAAVAPQRAPILR---PAFVPHVLQRADSALSSAAAGPRPMALRP 187 +H+ + F R+ R +LR PA P + AD A P P+ +P Sbjct: 308 NHIFHTSCLRSWFQRQQTCPTCRMDVLRASLPAQSPPPPEPADQG-PPPAPHPPPLLPQP 366 Query: 188 PH--QALVGPPLPGPPGPPMMLPPMARAPG--PPLGSMAALRPPLEEPAAPRELGLGLGL 243 P+ Q L+ PP P PG + PPM P PP S A+ PP A R G Sbjct: 367 PNFPQGLL-PPFP--PGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAALSRPSG----- 418 Query: 244 GLKEKEEAVVAAAAGLEEASAAVAV---GAGGAP-AGPAVIGPSLPLALAMPLPEP---E 296 A AAG +A+ G+G AP AGPA P P + MPLP P Sbjct: 419 -------AATTTAAGTSATAASATASGPGSGSAPEAGPAPGFPFPPPWMGMPLPPPFAFP 471 Query: 297 PLPLPLEVVRGLLP 310 P+P+P GL P Sbjct: 472 PMPVPPAGFAGLTP 485 Score = 34.7 bits (78), Expect = 0.20 Identities = 28/71 (39%), Positives = 31/71 (43%), Gaps = 11/71 (15%) Query: 274 PAGPAVIGPSLPLALAMPLPEPEPL-PLPLEVVRGLLPPLRIPELLSLRP--RPRPPRPE 330 P PA GP P P P PL P P +GLLPP P + L P P PP P Sbjct: 345 PPEPADQGPP-------PAPHPPPLLPQPPNFPQGLLPPFP-PGMFPLWPPMGPFPPVPP 396 Query: 331 PPPGLMALEVP 341 PP A+ P Sbjct: 397 PPSSGEAVAPP 407 >gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] Length = 636 Score = 56.6 bits (135), Expect = 5e-08 Identities = 31/94 (32%), Positives = 58/94 (61%), Gaps = 2/94 (2%) Query: 383 IFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREM 442 ++ + G +++D+ L F +F L KV+ D+ +GK+KG+GFVSF+ D +A+ EM Sbjct: 193 VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEM 251 Query: 443 NGKYVGSRPIKLRKSMWK-DRNLDVVRKKQKEKK 475 NGK + + I + ++ K +R ++ RK ++ K+ Sbjct: 252 NGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQ 285 Score = 53.5 bits (127), Expect = 4e-07 Identities = 25/79 (31%), Positives = 49/79 (62%), Gaps = 2/79 (2%) Query: 383 IFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREM 442 ++ +L + ++D+ L + FS F + AKV+ + G++KG+GFV F P + +A+ EM Sbjct: 296 LYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEG--GRSKGFGFVCFSSPEEATKAVTEM 353 Query: 443 NGKYVGSRPIKLRKSMWKD 461 NG+ V ++P+ + + K+ Sbjct: 354 NGRIVATKPLYVALAQRKE 372 Score = 52.0 bits (123), Expect = 1e-06 Identities = 26/81 (32%), Positives = 45/81 (55%), Gaps = 3/81 (3%) Query: 383 IFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREM 442 ++ GDL +V + +L FS L +V RD T ++ GY +V+F+ P+D RA+ M Sbjct: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72 Query: 443 NGKYVGSRPIKLRKSMWKDRN 463 N + +P+++ MW R+ Sbjct: 73 NFDVIKGKPVRI---MWSQRD 90 Score = 46.2 bits (108), Expect = 7e-05 Identities = 34/106 (32%), Positives = 51/106 (48%), Gaps = 12/106 (11%) Query: 347 DKKKGKPEKLKRCIRTAAGSSWEDPSLLEWDADDFRIFCGDLGNEVNDDILARAFSRFPS 406 D KGKP ++ S DPSL + + IF +L +++ L FS F + Sbjct: 75 DVIKGKPVRIMW--------SQRDPSLRKSGVGN--IFIKNLDKSIDNKALYDTFSAFGN 124 Query: 407 FLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREMNGKYVGSRPI 452 L KV+ D+ +KGYGFV F+ RA+ +MNG + R + Sbjct: 125 ILSCKVVCDENG--SKGYGFVHFETQEAAERAIEKMNGMLLNDRKV 168 >gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] Length = 424 Score = 55.8 bits (133), Expect = 8e-08 Identities = 30/80 (37%), Positives = 47/80 (58%), Gaps = 1/80 (1%) Query: 383 IFCGDLGNEVNDDILARAFSRFPSFLKA-KVIRDKRTGKTKGYGFVSFKDPSDYVRAMRE 441 IF G+L E+++ +L FS F L+ K++RD TG +KGY F++F A+ Sbjct: 102 IFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEA 161 Query: 442 MNGKYVGSRPIKLRKSMWKD 461 MNG+Y+ +RPI + + KD Sbjct: 162 MNGQYLCNRPITVSYAFKKD 181 Score = 49.3 bits (116), Expect = 8e-06 Identities = 26/87 (29%), Positives = 48/87 (55%) Query: 380 DFRIFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAM 439 D ++ G L +V++ +L F + + + +D+ TG+ +GYGFV F D A+ Sbjct: 12 DATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAI 71 Query: 440 REMNGKYVGSRPIKLRKSMWKDRNLDV 466 + MN + +PI++ K+ ++NLDV Sbjct: 72 KIMNMIKLYGKPIRVNKASAHNKNLDV 98 Score = 40.8 bits (94), Expect = 0.003 Identities = 56/190 (29%), Positives = 70/190 (36%), Gaps = 33/190 (17%) Query: 173 LSSAAAGPRPMALRPPHQALVGPPLPG--PPG-----PPMMLPPMARAPGPPLGSMAALR 225 +SS +G P + PP P PG PPG PP +PP A GPP Sbjct: 225 VSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAG 284 Query: 226 PPLEEPAAPRELGLGLGLGLKEKEEAVVA--AAAGLEEASAAVAVGAGGAPAG---PAVI 280 P + P G G+ + +A GL A G+GG P P + Sbjct: 285 HPGHGHSHPHPFPPG-GMPHPGMSQMQLAHHGPHGLGHPHAGPP-GSGGQPPPRPPPGMP 342 Query: 281 GPSLPLALAMP-------LPEPEPLPLPLEVVRGLLPPLRIPELLSLRPRPRP------- 326 P P + MP P P P+P +RG PPL P + PRP P Sbjct: 343 HPGPP-PMGMPPRGPPFGSPMGHPGPMPPHGMRGP-PPLMPPHGYTGPPRPPPYGYQRGP 400 Query: 327 ---PRPEPPP 333 PRP P P Sbjct: 401 LPPPRPTPRP 410 Score = 39.7 bits (91), Expect = 0.006 Identities = 56/176 (31%), Positives = 64/176 (36%), Gaps = 27/176 (15%) Query: 176 AAAGPRPMALRPPHQALVGPPLPGPPGPPMM-----LPPMARAPG-PPLGSMAALRPPLE 229 AA P A RP PP P P P + LPP PG PP GS PP+ Sbjct: 196 AAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPP----PGMPPPGSFP---PPVP 248 Query: 230 EPAAPRELGLGLGLGLKEKEEAVVAAAAGLEEASAAVAVGAGGAPAGPAVIGPSLPLALA 289 P A L G+ + AAG SA GAG G + P P Sbjct: 249 PPGA-----LPPGIPPAMPPPPMPPGAAGHGPPSAGTP-GAGHPGHGHSHPHPFPPGG-- 300 Query: 290 MPLPEPEPLPLPLEVVRGLLPPLRIPELLSLRPRPRPPRPEPPPGLMALEVPEPLG 345 MP P + L GL P P +P PRPP P PG P P+G Sbjct: 301 MPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPG------PPPMG 350 Score = 37.4 bits (85), Expect = 0.030 Identities = 68/293 (23%), Positives = 84/293 (28%), Gaps = 99/293 (33%) Query: 50 GAPVPGIPTAVPAVPTVPTVPTVEAMQVPAAPVIRPIIATNTYQQVQQTLEARAAAAATV 109 G P PG+P P P VP A+ P + P Sbjct: 231 GLPPPGMP---PPGSFPPPVPPPGALPPGIPPAMPP------------------------ 263 Query: 110 VPPMVGGPPFVGPVGFGPGDRSHLDSPEAREAMFLRRAAVAPQRAPILRPAFVPHVLQRA 169 PPM G GP G H + F P + + PH L Sbjct: 264 -PPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHP 322 Query: 170 DSALSSAAAGPRPMALRPPHQALVGPPLPGPPGPPMMLPPMARAPGPPLGSMAALRPPLE 229 + + P P RPP P +P P PPM +PP GPP GS P+ Sbjct: 323 HAGPPGSGGQPPP---RPP------PGMPHPGPPPMGMPPR----GPPFGS------PMG 363 Query: 230 EPAAPRELGLGLGLGLKEKEEAVVAAAAGLEEASAAVAVGAGGAPAGPAVIGPSLPLALA 289 P G+ GP + P P Sbjct: 364 HPGPMPPHGM-----------------------------------RGPPPLMP--PHGYT 386 Query: 290 MPLPEPEPLPLPLEVVRGLLPPLRIPELLSLRPRPRPPRPEPPPGLMALEVPE 342 P P P P RG LPP PRP P P PP G + +P+ Sbjct: 387 GP-----PRPPPYGYQRGPLPP----------PRPTPRPPVPPRGPLRGPLPQ 424 >gi|153252068 testes-specific heterogenous nuclear ribonucleoprotein G-T [Homo sapiens] Length = 392 Score = 55.8 bits (133), Expect = 8e-08 Identities = 23/76 (30%), Positives = 47/76 (61%) Query: 382 RIFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMRE 441 ++F G L E ++ L F ++ ++ +++D+ T K++G+ FV+F+ P+D A R+ Sbjct: 9 KLFIGGLNLETDEKALEAEFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKAAARD 68 Query: 442 MNGKYVGSRPIKLRKS 457 MNGK + + IK+ ++ Sbjct: 69 MNGKSLDGKAIKVAQA 84 >gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo sapiens] Length = 614 Score = 55.5 bits (132), Expect = 1e-07 Identities = 26/92 (28%), Positives = 53/92 (57%), Gaps = 2/92 (2%) Query: 383 IFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREM 442 ++ +L + ++DD L + FS + AKV+ + G +KG+GFV F P + +A+ EM Sbjct: 296 LYVKNLDDSIDDDKLRKEFSPYGVITSAKVMTEG--GHSKGFGFVCFSSPEEATKAVTEM 353 Query: 443 NGKYVGSRPIKLRKSMWKDRNLDVVRKKQKEK 474 NG+ VG++P+ + + K+ ++ + ++ Sbjct: 354 NGRIVGTKPLYVALAQRKEERKAILTNQYMQR 385 Score = 52.0 bits (123), Expect = 1e-06 Identities = 26/81 (32%), Positives = 46/81 (56%), Gaps = 3/81 (3%) Query: 383 IFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREM 442 ++ GDL +V + +L FS L +V RD T ++ GY +++F+ P+D RA+ M Sbjct: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDTM 72 Query: 443 NGKYVGSRPIKLRKSMWKDRN 463 N + + +PI++ MW R+ Sbjct: 73 NFEMLKGQPIRI---MWSQRD 90 Score = 44.3 bits (103), Expect = 2e-04 Identities = 27/98 (27%), Positives = 55/98 (56%), Gaps = 1/98 (1%) Query: 383 IFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYVRAMREM 442 I+ +L +V++ L FS+F L KV+RD +G ++ +GFV+F+ + +A+ M Sbjct: 193 IYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVVHM 251 Query: 443 NGKYVGSRPIKLRKSMWKDRNLDVVRKKQKEKKKLGLR 480 NGK V R + ++ + + ++++ ++ K+ LR Sbjct: 252 NGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLR 289 Score = 36.6 bits (83), Expect = 0.052 Identities = 25/86 (29%), Positives = 42/86 (48%), Gaps = 4/86 (4%) Query: 367 SWEDPSLLEWDADDFRIFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGF 426 S DP L + + IF +L + +++ L FS F + L KV D+ ++G+GF Sbjct: 87 SQRDPGLRKSGVGN--IFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHG--SRGFGF 142 Query: 427 VSFKDPSDYVRAMREMNGKYVGSRPI 452 V F+ +A+ MNG + R + Sbjct: 143 VHFETHEAAQQAINTMNGMLLNDRKV 168 >gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens] Length = 524 Score = 55.5 bits (132), Expect = 1e-07 Identities = 25/83 (30%), Positives = 46/83 (55%) Query: 372 SLLEWDADDFRIFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKD 431 +L + A R++ G L + +D+L F F +++ D TG++KGYGF++F D Sbjct: 241 NLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSD 300 Query: 432 PSDYVRAMREMNGKYVGSRPIKL 454 +A+ ++NG + RP+K+ Sbjct: 301 SECAKKALEQLNGFELAGRPMKV 323 Score = 30.0 bits (66), Expect = 4.9 Identities = 21/81 (25%), Positives = 36/81 (44%), Gaps = 1/81 (1%) Query: 377 DADDFRIFCGDLGNEVNDDILARAFSRFPSFLKAKVIRDKRTGKTKGYGFVSFKDPSDYV 436 + D +FC L + L FS ++I D+ + ++KG +V F D S Sbjct: 149 ERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVP 208 Query: 437 RAMREMNGKYVGSRPIKLRKS 457 A+ + G+ V PI ++ S Sbjct: 209 LAI-GLTGQRVLGVPIIVQAS 228 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.138 0.416 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 26,952,365 Number of Sequences: 37866 Number of extensions: 1982225 Number of successful extensions: 30875 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 549 Number of HSP's successfully gapped in prelim test: 1336 Number of HSP's that attempted gapping in prelim test: 13960 Number of HSP's gapped (non-prelim): 11572 length of query: 480 length of database: 18,247,518 effective HSP length: 106 effective length of query: 374 effective length of database: 14,233,722 effective search space: 5323412028 effective search space used: 5323412028 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.