BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sapiens] (325 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa... 680 0.0 gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap... 664 0.0 gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa... 626 e-180 gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa... 493 e-140 gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa... 456 e-128 gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sa... 297 1e-80 gi|21040355 hemochromatosis protein isoform 10 precursor [Homo s... 295 3e-80 gi|21040341 hemochromatosis protein isoform 3 precursor [Homo sa... 271 4e-73 gi|4504417 major histocompatibility complex, class I-related [Ho... 207 1e-53 gi|17986001 major histocompatibility complex, class I, B precurs... 201 6e-52 gi|24797067 major histocompatibility complex, class I, A precurs... 199 2e-51 gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapi... 197 1e-50 gi|52630342 major histocompatibility complex, class I, C precurs... 194 7e-50 gi|4504415 major histocompatibility complex, class I, G precurso... 191 8e-49 gi|149158702 major histocompatibility complex, class I, F isofor... 189 4e-48 gi|149158698 major histocompatibility complex, class I, F isofor... 189 4e-48 gi|62912479 major histocompatibility complex, class I, E precurs... 188 5e-48 gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens] 178 5e-45 gi|167857788 MHC class I polypeptide-related sequence B [Homo sa... 137 1e-32 gi|4557751 MHC class I polypeptide-related sequence A [Homo sapi... 130 1e-30 gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [H... 119 5e-27 gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Hom... 119 5e-27 gi|21040357 hemochromatosis protein isoform 11 precursor [Homo s... 99 5e-21 gi|239740918 PREDICTED: similar to major histocompatibility comp... 88 9e-18 gi|4502649 CD1D antigen precursor [Homo sapiens] 88 9e-18 gi|239740920 PREDICTED: similar to major histocompatibility comp... 88 1e-17 gi|150418002 major histocompatibility complex, class II, DQ beta... 86 6e-17 gi|169168591 PREDICTED: similar to major histocompatibility comp... 85 8e-17 gi|239748788 PREDICTED: similar to major histocompatibility comp... 81 1e-15 gi|239740863 PREDICTED: similar to major histocompatibility comp... 81 1e-15 >gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sapiens] Length = 325 Score = 680 bits (1755), Expect = 0.0 Identities = 325/325 (100%), Positives = 325/325 (100%) Query: 1 MGPRARPALLLLMLLQTAVLQGRLLPLGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQM 60 MGPRARPALLLLMLLQTAVLQGRLLPLGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQM Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLPLGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQM 60 Query: 61 WLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQ 120 WLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQ Sbjct: 61 WLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQ 120 Query: 121 DHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLD 180 DHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLD Sbjct: 121 DHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLD 180 Query: 181 QQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGT 240 QQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGT Sbjct: 181 QQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGT 240 Query: 241 YQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIG 300 YQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIG Sbjct: 241 YQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIG 300 Query: 301 ILFIILRKRQGSRGAMGHYVLAERE 325 ILFIILRKRQGSRGAMGHYVLAERE Sbjct: 301 ILFIILRKRQGSRGAMGHYVLAERE 325 >gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sapiens] Length = 348 Score = 664 bits (1713), Expect = 0.0 Identities = 324/348 (93%), Positives = 324/348 (93%), Gaps = 23/348 (6%) Query: 1 MGPRARPALLLLMLLQTAVLQGRLL-----------------------PLGYVDDQLFVF 37 MGPRARPALLLLMLLQTAVLQGRLL LGYVDDQLFVF Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60 Query: 38 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV 97 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV Sbjct: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV 120 Query: 98 ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR 157 ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR Sbjct: 121 ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR 180 Query: 158 AYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWL 217 AYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWL Sbjct: 181 AYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWL 240 Query: 218 KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS 277 KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS Sbjct: 241 KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS 300 Query: 278 PSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 325 PSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE Sbjct: 301 PSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 348 >gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sapiens] Length = 334 Score = 626 bits (1615), Expect = e-180 Identities = 310/348 (89%), Positives = 310/348 (89%), Gaps = 37/348 (10%) Query: 1 MGPRARPALLLLMLLQTAVLQGRLL-----------------------PLGYVDDQLFVF 37 MGPRARPALLLLMLLQTAVLQGRLL LGYVDDQLFVF Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60 Query: 38 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV 97 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV Sbjct: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV 120 Query: 98 ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR 157 ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR Sbjct: 121 ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR 180 Query: 158 AYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWL 217 AYLERDCPAQLQQLLELGRGVLDQQ VTTLRCRALNYYPQNITMKWL Sbjct: 181 AYLERDCPAQLQQLLELGRGVLDQQ--------------VTTLRCRALNYYPQNITMKWL 226 Query: 218 KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS 277 KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS Sbjct: 227 KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS 286 Query: 278 PSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 325 PSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE Sbjct: 287 PSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 334 >gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sapiens] Length = 260 Score = 493 bits (1270), Expect = e-140 Identities = 234/235 (99%), Positives = 235/235 (100%) Query: 91 ESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 150 +SHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK Sbjct: 26 QSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85 Query: 151 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQ 210 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQ Sbjct: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQ 145 Query: 211 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL 270 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL Sbjct: 146 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL 205 Query: 271 IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 325 IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE Sbjct: 206 IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 260 Score = 50.1 bits (118), Expect = 3e-06 Identities = 25/25 (100%), Positives = 25/25 (100%) Query: 1 MGPRARPALLLLMLLQTAVLQGRLL 25 MGPRARPALLLLMLLQTAVLQGRLL Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLL 25 >gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sapiens] Length = 246 Score = 456 bits (1172), Expect = e-128 Identities = 220/235 (93%), Positives = 221/235 (94%), Gaps = 14/235 (5%) Query: 91 ESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 150 +SHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK Sbjct: 26 QSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85 Query: 151 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQ 210 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQV TTLRCRALNYYPQ Sbjct: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQV--------------TTLRCRALNYYPQ 131 Query: 211 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL 270 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL Sbjct: 132 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL 191 Query: 271 IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 325 IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE Sbjct: 192 IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 246 Score = 50.1 bits (118), Expect = 3e-06 Identities = 25/25 (100%), Positives = 25/25 (100%) Query: 1 MGPRARPALLLLMLLQTAVLQGRLL 25 MGPRARPALLLLMLLQTAVLQGRLL Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLL 25 >gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sapiens] Length = 256 Score = 297 bits (760), Expect = 1e-80 Identities = 143/144 (99%), Positives = 144/144 (100%) Query: 182 QVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTY 241 +VPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTY Sbjct: 113 KVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTY 172 Query: 242 QGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGI 301 QGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGI Sbjct: 173 QGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGI 232 Query: 302 LFIILRKRQGSRGAMGHYVLAERE 325 LFIILRKRQGSRGAMGHYVLAERE Sbjct: 233 LFIILRKRQGSRGAMGHYVLAERE 256 Score = 174 bits (440), Expect = 1e-43 Identities = 89/113 (78%), Positives = 89/113 (78%), Gaps = 23/113 (20%) Query: 1 MGPRARPALLLLMLLQTAVLQGRLL-----------------------PLGYVDDQLFVF 37 MGPRARPALLLLMLLQTAVLQGRLL LGYVDDQLFVF Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60 Query: 38 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 90 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK Sbjct: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113 >gi|21040355 hemochromatosis protein isoform 10 precursor [Homo sapiens] Length = 168 Score = 295 bits (756), Expect = 3e-80 Identities = 142/143 (99%), Positives = 143/143 (100%) Query: 183 VPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 242 +PPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ Sbjct: 26 LPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 85 Query: 243 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL 302 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL Sbjct: 86 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL 145 Query: 303 FIILRKRQGSRGAMGHYVLAERE 325 FIILRKRQGSRGAMGHYVLAERE Sbjct: 146 FIILRKRQGSRGAMGHYVLAERE 168 Score = 50.1 bits (118), Expect = 3e-06 Identities = 25/25 (100%), Positives = 25/25 (100%) Query: 1 MGPRARPALLLLMLLQTAVLQGRLL 25 MGPRARPALLLLMLLQTAVLQGRLL Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLL 25 >gi|21040341 hemochromatosis protein isoform 3 precursor [Homo sapiens] Length = 242 Score = 271 bits (694), Expect = 4e-73 Identities = 131/135 (97%), Positives = 132/135 (97%) Query: 191 HHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVP 250 +H S VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVP Sbjct: 108 NHNHSKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVP 167 Query: 251 PGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ 310 PGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ Sbjct: 168 PGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ 227 Query: 311 GSRGAMGHYVLAERE 325 GSRGAMGHYVLAERE Sbjct: 228 GSRGAMGHYVLAERE 242 Score = 174 bits (440), Expect = 1e-43 Identities = 89/113 (78%), Positives = 89/113 (78%), Gaps = 23/113 (20%) Query: 1 MGPRARPALLLLMLLQTAVLQGRLL-----------------------PLGYVDDQLFVF 37 MGPRARPALLLLMLLQTAVLQGRLL LGYVDDQLFVF Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60 Query: 38 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 90 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK Sbjct: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113 >gi|4504417 major histocompatibility complex, class I-related [Homo sapiens] Length = 341 Score = 207 bits (526), Expect = 1e-53 Identities = 110/286 (38%), Positives = 165/286 (57%), Gaps = 5/286 (1%) Query: 25 LPLGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIME 84 + +GYVD YD +R+ EPR PW++ ++ W + +Q L+GW MF V+ + Sbjct: 45 ISVGYVDSHPITTYDSVTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQR 104 Query: 85 NHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKL 144 ++NHS SHT Q ++GCE+ ED ST G+ +Y YDGQD L F DTL W A + A K Sbjct: 105 HYNHSG-SHTYQRMIGCELLEDGSTTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQ 163 Query: 145 EWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVT-SSVTTLRCR 203 WE ++ + +LE +C A L++ LE G+ L + PPLV+V T VT L C+ Sbjct: 164 AWEANQHELLYQKNWLEEECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCK 223 Query: 204 ALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEH 263 A +YP I M W+K+ + + +E + D+LP+GDGTYQ W ++ + P Y+C VEH Sbjct: 224 AHGFYPPEIYMTWMKNGEEI-VQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEH 282 Query: 264 PGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR 309 G+ L V E S + LV+ +SG V V++L G+ ++ R+R Sbjct: 283 CGVHMVLQVPQE-SETIPLVMKAVSGSIVLVIVL-AGVGVLVWRRR 326 >gi|17986001 major histocompatibility complex, class I, B precursor [Homo sapiens] Length = 362 Score = 201 bits (512), Expect = 6e-52 Identities = 112/303 (36%), Positives = 170/303 (56%), Gaps = 9/303 (2%) Query: 23 RLLPLGYVDDQLFVFYDHE--SRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFW 80 R + +GYVDD FV +D + S R EPR PW+ + W + +Q K Sbjct: 45 RFISVGYVDDTQFVRFDSDAASPREEPRAPWIEQE-GPEYWDRNTQIYKAQAQTDRESLR 103 Query: 81 TIMENHNHSKE-SHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPR 138 + +N S+ SHTLQ + GC++ D G+ +Y YDG+D++ D W AA+ Sbjct: 104 NLRGYYNQSEAGSHTLQSMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTA 163 Query: 139 AWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSV 197 A T+ +WE + A Q RAYLE +C L++ LE G+ L++ PP VTHH ++ Sbjct: 164 AQITQRKWEAAR-EAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHE 222 Query: 198 TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRY 257 TLRC AL +YP IT+ W +D + ++ E + P GD T+Q W + VP GEEQRY Sbjct: 223 ATLRCWALGFYPAEITLTWQRDGEDQ-TQDTELVETRPAGDRTFQKWAAVVVPSGEEQRY 281 Query: 258 TCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 316 TC V+H GL +PL + WEPS T+ ++G+++G+AV V++ ++ ++ +R+ S G Sbjct: 282 TCHVQHEGLPKPLTLRWEPSSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKG 341 Query: 317 GHY 319 G Y Sbjct: 342 GSY 344 >gi|24797067 major histocompatibility complex, class I, A precursor [Homo sapiens] Length = 365 Score = 199 bits (507), Expect = 2e-51 Identities = 111/306 (36%), Positives = 172/306 (56%), Gaps = 9/306 (2%) Query: 23 RLLPLGYVDDQLFVFYDHE--SRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFW 80 R + +GYVDD FV +D + S+R+EPR PW+ + W Q ++++K VD Sbjct: 45 RFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQE-GPEYWDQETRNVKAQSQTDRVDLG 103 Query: 81 TIMENHNHSKE-SHTLQVILGCEMQEDNS-TEGYWKYGYDGQDHLEFCPDTLDWRAAEPR 138 T+ +N S+ SHT+Q++ GC++ D GY + YDG+D++ D W AA+ Sbjct: 104 TLRGYYNQSEAGSHTIQIMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMA 163 Query: 139 AWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSV 197 A TK +WE A Q RAYL+ C L++ LE G+ L + PP +THH ++ Sbjct: 164 AQITKRKWEAAH-EAEQLRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHE 222 Query: 198 TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRY 257 TLRC AL +YP IT+ W +D + ++ E + P GDGT+Q W + VP GEEQRY Sbjct: 223 ATLRCWALGFYPAEITLTWQRDGEDQ-TQDTELVETRPAGDGTFQKWAAVVVPSGEEQRY 281 Query: 258 TCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 316 TC V+H GL +PL + WE S T+ ++G+I+G+ + ++ ++ ++ +R+ S Sbjct: 282 TCHVQHEGLPKPLTLRWELSSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKG 341 Query: 317 GHYVLA 322 G Y A Sbjct: 342 GSYTQA 347 >gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapiens] Length = 366 Score = 197 bits (501), Expect = 1e-50 Identities = 114/300 (38%), Positives = 168/300 (56%), Gaps = 9/300 (3%) Query: 23 RLLPLGYVDDQLFVFYDHESR--RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFW 80 R + +GYVDD FV +D +S R EPR PW+ + W + ++ +K F V Sbjct: 58 RFISVGYVDDTQFVRFDSDSANPREEPRAPWMEQE-GPEYWDEQTRIVKDTAQSFRVGLN 116 Query: 81 TIMENHNHSKE-SHTLQVILGCEMQEDNS-TEGYWKYGYDGQDHLEFCPDTLDWRAAEPR 138 T+ +N S+ SHTLQ++ GC++ D G+ + YDG+D++ D W AA+ Sbjct: 117 TLRGYYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDGRDYIALNEDLRSWTAADTA 176 Query: 139 AWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSV 197 A TK + E RQ R YLE C L++ LE G+ L + PP VTHH ++ Sbjct: 177 AQITKRKREAAGAAERQ-RNYLEGRCVEGLRRYLETGKDALLRADPPKAHVTHHPISERE 235 Query: 198 TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRY 257 TLRC AL +YP+ I++ W ++ + ++ E + P+GDGT+Q W L VP GEEQRY Sbjct: 236 VTLRCWALGFYPEEISLTWQREGEDQ-TQDMELVETRPSGDGTFQKWAALVVPSGEEQRY 294 Query: 258 TCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMG 317 TC+V+H GL +PL + WEP + L++G+I G+ + VV L G + I +KR G G G Sbjct: 295 TCRVQHEGLQEPLTLRWEPPQTSFLIMGIIVGLVLLVVALVAGAV-IWRKKRSGREGREG 353 >gi|52630342 major histocompatibility complex, class I, C precursor [Homo sapiens] Length = 366 Score = 194 bits (494), Expect = 7e-50 Identities = 114/301 (37%), Positives = 166/301 (55%), Gaps = 9/301 (2%) Query: 23 RLLPLGYVDDQLFVFYDHE--SRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFW 80 R + +GYVDD FV +D + S R EPR PWV + W + +Q K V Sbjct: 45 RFISVGYVDDTQFVRFDSDAASPRGEPRAPWVEQE-GPEYWDRETQKYKRQAQADRVSLR 103 Query: 81 TIMENHNHSKE-SHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPR 138 + +N S++ SHTLQ + GC++ D GY + YDG+D++ D W AA+ Sbjct: 104 NLRGYYNQSEDGSHTLQRMSGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTA 163 Query: 139 AWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSS-V 197 A T+ + E + A Q RAYLE C L++ LE G+ L + PP VTHH S Sbjct: 164 AQITQRKLEAARA-AEQLRAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHE 222 Query: 198 TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRY 257 TLRC AL +YP IT+ W +D + ++ E + P GDGT+Q W + VP G+EQRY Sbjct: 223 ATLRCWALGFYPAEITLTWQRDGEDQ-TQDTELVETRPAGDGTFQKWAAVVVPSGQEQRY 281 Query: 258 TCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 316 TC ++H GL +PL + WEPS T+ ++G+++G+AV VV+ +G + + R+ S G Sbjct: 282 TCHMQHEGLQEPLTLSWEPSSQPTIPIMGIVAGLAVLVVLAVLGAVVTAMMCRRKSSGGK 341 Query: 317 G 317 G Sbjct: 342 G 342 >gi|4504415 major histocompatibility complex, class I, G precursor [Homo sapiens] Length = 338 Score = 191 bits (485), Expect = 8e-49 Identities = 108/296 (36%), Positives = 166/296 (56%), Gaps = 9/296 (3%) Query: 23 RLLPLGYVDDQLFVFYDHESR--RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFW 80 R + +GYVDD FV +D +S R+EPR PWV + W + +++ K ++ Sbjct: 45 RFIAMGYVDDTQFVRFDSDSACPRMEPRAPWVEQE-GPEYWEEETRNTKAHAQTDRMNLQ 103 Query: 81 TIMENHNHSK-ESHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPR 138 T+ +N S+ SHTLQ ++GC++ D GY +Y YDG+D+L D W AA+ Sbjct: 104 TLRGYYNQSEASSHTLQWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTA 163 Query: 139 AWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSV 197 A +K + E + A Q RAYLE C L + LE G+ +L + PP VTHH V Sbjct: 164 AQISKRKCEAANV-AEQRRAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYE 222 Query: 198 TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRY 257 TLRC AL +YP I + W +D + ++ E + P GDGT+Q W + VP GEEQRY Sbjct: 223 ATLRCWALGFYPAEIILTWQRDGEDQ-TQDVELVETRPAGDGTFQKWAAVVVPSGEEQRY 281 Query: 258 TCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGS 312 TC V+H GL +PL++ W+ S T+ ++G+++G+ V ++ + +L +++ S Sbjct: 282 TCHVQHEGLPEPLMLRWKQSSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSS 337 >gi|149158702 major histocompatibility complex, class I, F isoform 1 precursor [Homo sapiens] Length = 442 Score = 189 bits (479), Expect = 4e-48 Identities = 108/303 (35%), Positives = 166/303 (54%), Gaps = 9/303 (2%) Query: 23 RLLPLGYVDDQLFVFYDHESR--RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFW 80 R + + YVDD F+ +D ++ R+EPR PWV Q W + K V Sbjct: 42 RYIAVEYVDDTQFLRFDSDAAIPRMEPREPWVEQE-GPQYWEWTTGYAKANAQTDRVALR 100 Query: 81 TIMENHNHSKE-SHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPR 138 ++ +N S+ SHTLQ + GC+M D GY ++ YDG+D++ D W AA+ Sbjct: 101 NLLRRYNQSEAGSHTLQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTV 160 Query: 139 AWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSV 197 A T+ +E + A + R YLE +C L++ LE G+ L + PP V HH ++ Sbjct: 161 AQITQRFYEAEEY-AEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHE 219 Query: 198 TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRY 257 TLRC AL +YP IT+ W +D + ++ E + P GDGT+Q W + VPPGEEQRY Sbjct: 220 ATLRCWALGFYPAEITLTWQRDGEEQ-TQDTELVETRPAGDGTFQKWAAVVVPPGEEQRY 278 Query: 258 TCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 316 TC V+H GL QPLI+ WE SP T+ ++G+++G+ V ++ ++ ++ +++ S Sbjct: 279 TCHVQHEGLPQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNR 338 Query: 317 GHY 319 G Y Sbjct: 339 GSY 341 >gi|149158698 major histocompatibility complex, class I, F isoform 2 precursor [Homo sapiens] Length = 346 Score = 189 bits (479), Expect = 4e-48 Identities = 108/303 (35%), Positives = 166/303 (54%), Gaps = 9/303 (2%) Query: 23 RLLPLGYVDDQLFVFYDHESR--RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFW 80 R + + YVDD F+ +D ++ R+EPR PWV Q W + K V Sbjct: 42 RYIAVEYVDDTQFLRFDSDAAIPRMEPREPWVEQE-GPQYWEWTTGYAKANAQTDRVALR 100 Query: 81 TIMENHNHSKE-SHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPR 138 ++ +N S+ SHTLQ + GC+M D GY ++ YDG+D++ D W AA+ Sbjct: 101 NLLRRYNQSEAGSHTLQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTV 160 Query: 139 AWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSV 197 A T+ +E + A + R YLE +C L++ LE G+ L + PP V HH ++ Sbjct: 161 AQITQRFYEAEEY-AEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHE 219 Query: 198 TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRY 257 TLRC AL +YP IT+ W +D + ++ E + P GDGT+Q W + VPPGEEQRY Sbjct: 220 ATLRCWALGFYPAEITLTWQRDGEEQ-TQDTELVETRPAGDGTFQKWAAVVVPPGEEQRY 278 Query: 258 TCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 316 TC V+H GL QPLI+ WE SP T+ ++G+++G+ V ++ ++ ++ +++ S Sbjct: 279 TCHVQHEGLPQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNR 338 Query: 317 GHY 319 G Y Sbjct: 339 GSY 341 >gi|62912479 major histocompatibility complex, class I, E precursor [Homo sapiens] Length = 358 Score = 188 bits (478), Expect = 5e-48 Identities = 108/307 (35%), Positives = 170/307 (55%), Gaps = 9/307 (2%) Query: 23 RLLPLGYVDDQLFVFYDHE--SRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFW 80 R + +GYVDD FV +D++ S R+ PR PW+ S+ W + ++S + +F V+ Sbjct: 42 RFISVGYVDDTQFVRFDNDAASPRMVPRAPWMEQE-GSEYWDRETRSARDTAQIFRVNLR 100 Query: 81 TIMENHNHSKE-SHTLQVILGCEMQEDNS-TEGYWKYGYDGQDHLEFCPDTLDWRAAEPR 138 T+ +N S+ SHTLQ + GCE+ D GY ++ YDG+D+L D W A + Sbjct: 101 TLRGYYNQSEAGSHTLQWMHGCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTA 160 Query: 139 AWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSV 197 A ++ + A RAYLE C L + LE G+ L PP VTHH ++ Sbjct: 161 AQISEQK-SNDASEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHE 219 Query: 198 TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRY 257 TLRC AL +YP IT+ W +D + ++ E + P GDGT+Q W + VP GEEQRY Sbjct: 220 ATLRCWALGFYPAEITLTWQQDGEG-HTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRY 278 Query: 258 TCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 316 TC V+H GL +P+ + W+P+ T+ ++G+I+G+ + ++ ++ ++ +++ S G Sbjct: 279 TCHVQHEGLPEPVTLRWKPASQPTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKG 338 Query: 317 GHYVLAE 323 G Y AE Sbjct: 339 GSYSKAE 345 >gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens] Length = 298 Score = 178 bits (452), Expect = 5e-45 Identities = 95/255 (37%), Positives = 142/255 (55%), Gaps = 10/255 (3%) Query: 27 LGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENH 86 LG ++D F Y+ + R+ +P W + W Q SQ K + +F I+E + Sbjct: 50 LGSLNDLQFFRYNSKDRKSQPMGLWRQVE-GMEDWKQDSQLQKAREDIFMETLKDIVEYY 108 Query: 87 NHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEW 146 N S SH LQ GCE++ + S+ +WKY YDG+D++EF + W +P A TK +W Sbjct: 109 NDSNGSHVLQGRFGCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKW 168 Query: 147 ERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVT-HHVTSSVTTLRCRAL 205 E + ++ +AYLE +CPA L++ L+ + +LD+Q PP V VT H L+C A Sbjct: 169 EAEPVYVQRAKAYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAY 228 Query: 206 NYYPQNITMKWLKDKQPMDAKEFEPK---DVLPNGDGTYQGWITLAVPPGEEQRYTCQVE 262 ++YP I + W + + EP+ DVL NG+GTYQ W+ +AVPP + Y+C V+ Sbjct: 229 DFYPGKIDVHWTRAGEVQ-----EPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQ 283 Query: 263 HPGLDQPLIVIWEPS 277 H L QPL+V WE S Sbjct: 284 HSSLAQPLVVPWEAS 298 >gi|167857788 MHC class I polypeptide-related sequence B [Homo sapiens] Length = 383 Score = 137 bits (346), Expect = 1e-32 Identities = 88/284 (30%), Positives = 145/284 (51%), Gaps = 23/284 (8%) Query: 11 LLMLLQTAVLQGRLLPLGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKG 70 L++L Q +Q L G++D Q F+ YD + RR +P+ W + + ++ W ++ L Sbjct: 32 LMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKRRAKPQGQWAENVLGAKTWDTETEDL-- 89 Query: 71 WDHMFTVDFWTIMENHNHSKES----HTLQVILGCEMQEDNSTEGYWKYGYDGQ----DH 122 T + + H K+ H+LQ I CE+ ED+ST G + YDG+ + Sbjct: 90 -----TENGQDLRRTLTHIKDQKGGLHSLQEIRVCEIHEDSSTRGSRHFYYDGELFLSQN 144 Query: 123 LEFCPDTLDWRA-AEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQ 181 LE T+ + A+ A W+ ++ + + ++ DC +LQ+ L+ G + + Sbjct: 145 LETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRAMQADCLQKLQRYLKSGVAIR-R 203 Query: 182 QVPPLVKVT-HHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGT 240 VPP+V VT V+ T+ CRA ++YP+NIT+ W +D + + DVLP+G+GT Sbjct: 204 TVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVLPDGNGT 263 Query: 241 YQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVI 284 YQ W+ + GEEQR+TC +EH G P PSG ++ Sbjct: 264 YQTWVATRIRQGEEQRFTCYMEHSGNHGT-----HPVPSGKALV 302 >gi|4557751 MHC class I polypeptide-related sequence A [Homo sapiens] Length = 383 Score = 130 bits (328), Expect = 1e-30 Identities = 93/316 (29%), Positives = 149/316 (47%), Gaps = 28/316 (8%) Query: 2 GPRARPALL---LLMLLQTAVLQGRLLPLGYVDDQLFVFYDHESRRVEPRTPWVSSRISS 58 G A P L L +L +Q L ++D Q F+ D + R +P+ W + + Sbjct: 20 GAAAEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCDRQKCRAKPQGQWAEDVLGN 79 Query: 59 QMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYD 118 + W + ++ L G + T+ + + H+LQ I CE+ EDNST + YD Sbjct: 80 KTWDRETRDLTGNGKDLRM---TLAHIKDQKEGLHSLQEIRVCEIHEDNSTRSSQHFYYD 136 Query: 119 GQDHLEFCPDTLDWRA-----AEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLE 173 G+ L +T +W A+ A + + ++ + + + DC +L++ L+ Sbjct: 137 GELFLSQNLETKEWTMPQSSRAQTLAMNVRNFLKEDAMKTKTHYHAMHADCLQELRRYLK 196 Query: 174 LGRGVLDQQVPPLVKVTHHVTSSVT-TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKD 232 G VL + VPP+V VT S T+ CRA +YP NIT+ W +D + + D Sbjct: 197 SGV-VLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITLSWRQDGVSLSHDTQQWGD 255 Query: 233 VLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSG----------TL 282 VLP+G+GTYQ W+ + GEEQR+TC +EH G P PSG T Sbjct: 256 VLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHST-----HPVPSGKVLVLQSHWQTF 310 Query: 283 VIGVISGIAVFVVILF 298 + ++ A+FV+I+F Sbjct: 311 HVSAVAAAAIFVIIIF 326 >gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [Homo sapiens] Length = 365 Score = 119 bits (297), Expect = 5e-27 Identities = 77/277 (27%), Positives = 132/277 (47%), Gaps = 10/277 (3%) Query: 28 GYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHN 87 G++ Q ++ Y+ EP WV S W + + L+ + +F F + Sbjct: 51 GWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKAL----- 105 Query: 88 HSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWE 147 K +TLQ +LGCE+ DN++ K+ +G++ + F W P A W+ Sbjct: 106 GGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQ 165 Query: 148 RHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTS-SVTTLRCRALN 206 + A + +L CP +L++ LE GRG L+ + PP +++ +S + L C A + Sbjct: 166 QQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFS 225 Query: 207 YYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGL 266 +YP + +++L++ + D PN DG++ +L V G+E Y C V+H GL Sbjct: 226 FYPPELQLRFLRNGLAAGTGQ---GDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGL 282 Query: 267 DQPLIVIWE-PSPSGTLVIGVISGIAVFVVILFIGIL 302 QPL V E P+ S LV+G++ G+ + G L Sbjct: 283 AQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGAL 319 >gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Homo sapiens] Length = 365 Score = 119 bits (297), Expect = 5e-27 Identities = 77/277 (27%), Positives = 132/277 (47%), Gaps = 10/277 (3%) Query: 28 GYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHN 87 G++ Q ++ Y+ EP WV S W + + L+ + +F F + Sbjct: 51 GWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKAL----- 105 Query: 88 HSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWE 147 K +TLQ +LGCE+ DN++ K+ +G++ + F W P A W+ Sbjct: 106 GGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQ 165 Query: 148 RHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTS-SVTTLRCRALN 206 + A + +L CP +L++ LE GRG L+ + PP +++ +S + L C A + Sbjct: 166 QQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFS 225 Query: 207 YYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGL 266 +YP + +++L++ + D PN DG++ +L V G+E Y C V+H GL Sbjct: 226 FYPPELQLRFLRNGLAAGTGQ---GDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGL 282 Query: 267 DQPLIVIWE-PSPSGTLVIGVISGIAVFVVILFIGIL 302 QPL V E P+ S LV+G++ G+ + G L Sbjct: 283 AQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGAL 319 >gi|21040357 hemochromatosis protein isoform 11 precursor [Homo sapiens] Length = 76 Score = 99.0 bits (245), Expect = 5e-21 Identities = 50/51 (98%), Positives = 51/51 (100%) Query: 275 EPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 325 +PSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE Sbjct: 26 QPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 76 Score = 50.1 bits (118), Expect = 3e-06 Identities = 25/25 (100%), Positives = 25/25 (100%) Query: 1 MGPRARPALLLLMLLQTAVLQGRLL 25 MGPRARPALLLLMLLQTAVLQGRLL Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLL 25 >gi|239740918 PREDICTED: similar to major histocompatibility complex, class II, DQ beta 1 isoform 1 [Homo sapiens] Length = 281 Score = 88.2 bits (217), Expect = 9e-18 Identities = 66/218 (30%), Positives = 103/218 (47%), Gaps = 12/218 (5%) Query: 107 NSTE---GYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERD 163 N TE G +Y Y+ +++ F D +RA P P W K + RA L+ Sbjct: 51 NGTERVRGVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTV 110 Query: 164 CPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVT---TLRCRALNYYPQNITMKWLKDK 220 C Q LEL R L ++V P V ++ T ++ L C ++YP I ++W ++ Sbjct: 111 CRHNYQ--LEL-RTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRND 167 Query: 221 QPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSG 280 Q + ++ NGD T+Q + L + P YTC VEHP L P+IV W + S Sbjct: 168 QE-ETTGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWR-AQSE 225 Query: 281 TLVIGVISGIAVFVV-ILFIGILFIILRKRQGSRGAMG 317 + ++SGI FV+ ++F+G+ II + Q G Sbjct: 226 SAQSKMLSGIGGFVLGLIFLGLGLIIHHRSQKGEEPQG 263 >gi|4502649 CD1D antigen precursor [Homo sapiens] Length = 335 Score = 88.2 bits (217), Expect = 9e-18 Identities = 77/289 (26%), Positives = 127/289 (43%), Gaps = 30/289 (10%) Query: 38 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTL-- 95 + ++S V PW S Q W L + + FT D + E + S+ L Sbjct: 58 WSNDSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRD---VKEFAKMLRLSYPLEL 114 Query: 96 QVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKL--------EWE 147 QV GCE+ N++ ++ + G+D L F W + L +W Sbjct: 115 QVSAGCEVHPGNASNNFFHVAFQGKDILSF--QGTSWEPTQEAPLWVNLAIQVLNQDKWT 172 Query: 148 RHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLR--CRAL 205 R ++ N CP + LLE G+ L +QV P ++ + L C Sbjct: 173 RETVQWLLNGT-----CPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVS 227 Query: 206 NYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPG 265 +YP+ + +KW++ +Q + P D+LPN D T+ TL V GE +C+V+H Sbjct: 228 GFYPKPVWVKWMRGEQEQQGTQ--PGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSS 285 Query: 266 LD-QPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILR-KRQGS 312 L+ Q +++ W S + +G+I+ +AV +LF+ I+ R KRQ S Sbjct: 286 LEGQDIVLYWGGSYTS---MGLIA-LAVLACLLFLLIVGFTSRFKRQTS 330 >gi|239740920 PREDICTED: similar to major histocompatibility complex, class II, DQ beta 1 isoform 2 [Homo sapiens] Length = 261 Score = 87.8 bits (216), Expect = 1e-17 Identities = 65/211 (30%), Positives = 102/211 (48%), Gaps = 12/211 (5%) Query: 107 NSTE---GYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERD 163 N TE G +Y Y+ +++ F D +RA P P W K + RA L+ Sbjct: 51 NGTERVRGVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTV 110 Query: 164 CPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVT---TLRCRALNYYPQNITMKWLKDK 220 C Q LEL R L ++V P V ++ T ++ L C ++YP I ++W ++ Sbjct: 111 CRHNYQ--LEL-RTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRND 167 Query: 221 QPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSG 280 Q + ++ NGD T+Q + L + P YTC VEHP L P+IV W + S Sbjct: 168 QE-ETTGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWR-AQSE 225 Query: 281 TLVIGVISGIAVFVV-ILFIGILFIILRKRQ 310 + ++SGI FV+ ++F+G+ II + Q Sbjct: 226 SAQSKMLSGIGGFVLGLIFLGLGLIIHHRSQ 256 >gi|150418002 major histocompatibility complex, class II, DQ beta 1 precursor [Homo sapiens] Length = 261 Score = 85.5 bits (210), Expect = 6e-17 Identities = 57/201 (28%), Positives = 97/201 (48%), Gaps = 9/201 (4%) Query: 114 KYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLE 173 +Y Y+ +++ F D +RA P+ P W K RA L+ C + Sbjct: 61 RYIYNREEYARFDSDVGVYRAVTPQGRPDAEYWNSQKEVLEGTRAELDTVCRHNYEVAF- 119 Query: 174 LGRGVLDQQVPPLVKVTHHVTSSVT---TLRCRALNYYPQNITMKWLKDKQPMDAKEFEP 230 RG+L ++V P V ++ T ++ L C ++YP I ++W ++ Q A Sbjct: 120 --RGILQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPGQIKVRWFRNDQEETAGVVST 177 Query: 231 KDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGI 290 ++ NGD T+Q + L + P YTC VEHP L P+ V W + S + ++SG+ Sbjct: 178 P-LIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWR-AQSESAQSKMLSGV 235 Query: 291 AVFVV-ILFIGILFIILRKRQ 310 FV+ ++F+G+ II ++ Q Sbjct: 236 GGFVLGLIFLGLGLIIRQRSQ 256 >gi|169168591 PREDICTED: similar to major histocompatibility complex, class II, DR beta 5 isoform 1 [Homo sapiens] Length = 261 Score = 85.1 bits (209), Expect = 8e-17 Identities = 64/211 (30%), Positives = 101/211 (47%), Gaps = 12/211 (5%) Query: 107 NSTE---GYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERD 163 N TE G +Y Y+ +++ F D +RA P P W K + RA ++ Sbjct: 51 NGTERVRGVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRASVDTV 110 Query: 164 CPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVT---TLRCRALNYYPQNITMKWLKDK 220 C Q LEL R L ++V P V ++ T ++ L C ++YP I ++W ++ Sbjct: 111 CRHNYQ--LEL-RTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRND 167 Query: 221 QPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSG 280 Q A ++ NGD T+Q + L + P YTC VEHP L P+ V W + S Sbjct: 168 QEETAGVVSTP-LIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWR-AQSE 225 Query: 281 TLVIGVISGIAVFVV-ILFIGILFIILRKRQ 310 + ++SGI FV+ ++F+G+ II + Q Sbjct: 226 SAQSKMLSGIGGFVLGLIFLGLGLIIHHRSQ 256 >gi|239748788 PREDICTED: similar to major histocompatibility complex, class II, DR beta 5 isoform 2 [Homo sapiens] Length = 281 Score = 81.3 bits (199), Expect = 1e-15 Identities = 60/205 (29%), Positives = 97/205 (47%), Gaps = 9/205 (4%) Query: 117 YDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGR 176 Y+ ++ + F D ++RA P W K + RA ++R C Q LEL R Sbjct: 64 YNREEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQ--LEL-R 120 Query: 177 GVLDQQVPPLVKVTHHVTSSVT---TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDV 233 L ++V P V ++ T ++ L C ++YP I ++W ++ Q A + Sbjct: 121 TTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTP-L 179 Query: 234 LPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVF 293 + NGD T+Q + L + P YTC VEHP L P+ V W + S + ++SGI F Sbjct: 180 IRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWR-AQSESAQSKMLSGIGGF 238 Query: 294 VV-ILFIGILFIILRKRQGSRGAMG 317 V+ ++F+G+ II + Q G Sbjct: 239 VLGLIFLGLGLIIHHRSQKGEEPQG 263 >gi|239740863 PREDICTED: similar to major histocompatibility complex, class II, DR beta 5 [Homo sapiens] Length = 281 Score = 81.3 bits (199), Expect = 1e-15 Identities = 60/205 (29%), Positives = 97/205 (47%), Gaps = 9/205 (4%) Query: 117 YDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGR 176 Y+ ++ + F D ++RA P W K + RA ++R C Q LEL R Sbjct: 64 YNREEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQ--LEL-R 120 Query: 177 GVLDQQVPPLVKVTHHVTSSVT---TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDV 233 L ++V P V ++ T ++ L C ++YP I ++W ++ Q A + Sbjct: 121 TTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTP-L 179 Query: 234 LPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVF 293 + NGD T+Q + L + P YTC VEHP L P+ V W + S + ++SGI F Sbjct: 180 IRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWR-AQSESAQSKMLSGIGGF 238 Query: 294 VV-ILFIGILFIILRKRQGSRGAMG 317 V+ ++F+G+ II + Q G Sbjct: 239 VLGLIFLGLGLIIHHRSQKGEEPQG 263 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.138 0.444 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,723,768 Number of Sequences: 37866 Number of extensions: 646399 Number of successful extensions: 1763 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 89 Number of HSP's successfully gapped in prelim test: 38 Number of HSP's that attempted gapping in prelim test: 1521 Number of HSP's gapped (non-prelim): 152 length of query: 325 length of database: 18,247,518 effective HSP length: 102 effective length of query: 223 effective length of database: 14,385,186 effective search space: 3207896478 effective search space used: 3207896478 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.