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Search of human proteins with 21040353
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21040353 hemochromatosis protein isoform 9 precursor [Homo
sapiens]
(325 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa... 680 0.0
gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap... 664 0.0
gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa... 626 e-180
gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa... 493 e-140
gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa... 456 e-128
gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sa... 297 1e-80
gi|21040355 hemochromatosis protein isoform 10 precursor [Homo s... 295 3e-80
gi|21040341 hemochromatosis protein isoform 3 precursor [Homo sa... 271 4e-73
gi|4504417 major histocompatibility complex, class I-related [Ho... 207 1e-53
gi|17986001 major histocompatibility complex, class I, B precurs... 201 6e-52
gi|24797067 major histocompatibility complex, class I, A precurs... 199 2e-51
gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapi... 197 1e-50
gi|52630342 major histocompatibility complex, class I, C precurs... 194 7e-50
gi|4504415 major histocompatibility complex, class I, G precurso... 191 8e-49
gi|149158702 major histocompatibility complex, class I, F isofor... 189 4e-48
gi|149158698 major histocompatibility complex, class I, F isofor... 189 4e-48
gi|62912479 major histocompatibility complex, class I, E precurs... 188 5e-48
gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens] 178 5e-45
gi|167857788 MHC class I polypeptide-related sequence B [Homo sa... 137 1e-32
gi|4557751 MHC class I polypeptide-related sequence A [Homo sapi... 130 1e-30
gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [H... 119 5e-27
gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Hom... 119 5e-27
gi|21040357 hemochromatosis protein isoform 11 precursor [Homo s... 99 5e-21
gi|239740918 PREDICTED: similar to major histocompatibility comp... 88 9e-18
gi|4502649 CD1D antigen precursor [Homo sapiens] 88 9e-18
gi|239740920 PREDICTED: similar to major histocompatibility comp... 88 1e-17
gi|150418002 major histocompatibility complex, class II, DQ beta... 86 6e-17
gi|169168591 PREDICTED: similar to major histocompatibility comp... 85 8e-17
gi|239748788 PREDICTED: similar to major histocompatibility comp... 81 1e-15
gi|239740863 PREDICTED: similar to major histocompatibility comp... 81 1e-15
>gi|21040353 hemochromatosis protein isoform 9 precursor [Homo
sapiens]
Length = 325
Score = 680 bits (1755), Expect = 0.0
Identities = 325/325 (100%), Positives = 325/325 (100%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLLPLGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQM 60
MGPRARPALLLLMLLQTAVLQGRLLPLGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQM
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLPLGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQM 60
Query: 61 WLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQ 120
WLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQ
Sbjct: 61 WLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQ 120
Query: 121 DHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLD 180
DHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLD
Sbjct: 121 DHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLD 180
Query: 181 QQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGT 240
QQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGT
Sbjct: 181 QQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGT 240
Query: 241 YQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIG 300
YQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIG
Sbjct: 241 YQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIG 300
Query: 301 ILFIILRKRQGSRGAMGHYVLAERE 325
ILFIILRKRQGSRGAMGHYVLAERE
Sbjct: 301 ILFIILRKRQGSRGAMGHYVLAERE 325
>gi|4504377 hemochromatosis protein isoform 1 precursor [Homo
sapiens]
Length = 348
Score = 664 bits (1713), Expect = 0.0
Identities = 324/348 (93%), Positives = 324/348 (93%), Gaps = 23/348 (6%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLL-----------------------PLGYVDDQLFVF 37
MGPRARPALLLLMLLQTAVLQGRLL LGYVDDQLFVF
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
Query: 38 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV 97
YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV
Sbjct: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV 120
Query: 98 ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR 157
ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR
Sbjct: 121 ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR 180
Query: 158 AYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWL 217
AYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWL
Sbjct: 181 AYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWL 240
Query: 218 KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS 277
KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS
Sbjct: 241 KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS 300
Query: 278 PSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 325
PSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
Sbjct: 301 PSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 348
>gi|21040347 hemochromatosis protein isoform 6 precursor [Homo
sapiens]
Length = 334
Score = 626 bits (1615), Expect = e-180
Identities = 310/348 (89%), Positives = 310/348 (89%), Gaps = 37/348 (10%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLL-----------------------PLGYVDDQLFVF 37
MGPRARPALLLLMLLQTAVLQGRLL LGYVDDQLFVF
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
Query: 38 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV 97
YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV
Sbjct: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQV 120
Query: 98 ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR 157
ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR
Sbjct: 121 ILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNR 180
Query: 158 AYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWL 217
AYLERDCPAQLQQLLELGRGVLDQQ VTTLRCRALNYYPQNITMKWL
Sbjct: 181 AYLERDCPAQLQQLLELGRGVLDQQ--------------VTTLRCRALNYYPQNITMKWL 226
Query: 218 KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS 277
KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS
Sbjct: 227 KDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPS 286
Query: 278 PSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 325
PSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
Sbjct: 287 PSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 334
>gi|21040349 hemochromatosis protein isoform 7 precursor [Homo
sapiens]
Length = 260
Score = 493 bits (1270), Expect = e-140
Identities = 234/235 (99%), Positives = 235/235 (100%)
Query: 91 ESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 150
+SHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK
Sbjct: 26 QSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
Query: 151 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQ 210
IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQ
Sbjct: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQ 145
Query: 211 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL 270
NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL
Sbjct: 146 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL 205
Query: 271 IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 325
IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
Sbjct: 206 IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 260
Score = 50.1 bits (118), Expect = 3e-06
Identities = 25/25 (100%), Positives = 25/25 (100%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLL 25
MGPRARPALLLLMLLQTAVLQGRLL
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLL 25
>gi|21040351 hemochromatosis protein isoform 8 precursor [Homo
sapiens]
Length = 246
Score = 456 bits (1172), Expect = e-128
Identities = 220/235 (93%), Positives = 221/235 (94%), Gaps = 14/235 (5%)
Query: 91 ESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 150
+SHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK
Sbjct: 26 QSHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHK 85
Query: 151 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQ 210
IRARQNRAYLERDCPAQLQQLLELGRGVLDQQV TTLRCRALNYYPQ
Sbjct: 86 IRARQNRAYLERDCPAQLQQLLELGRGVLDQQV--------------TTLRCRALNYYPQ 131
Query: 211 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL 270
NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL
Sbjct: 132 NITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPL 191
Query: 271 IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 325
IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
Sbjct: 192 IVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 246
Score = 50.1 bits (118), Expect = 3e-06
Identities = 25/25 (100%), Positives = 25/25 (100%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLL 25
MGPRARPALLLLMLLQTAVLQGRLL
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLL 25
>gi|21040343 hemochromatosis protein isoform 4 precursor [Homo
sapiens]
Length = 256
Score = 297 bits (760), Expect = 1e-80
Identities = 143/144 (99%), Positives = 144/144 (100%)
Query: 182 QVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTY 241
+VPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTY
Sbjct: 113 KVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTY 172
Query: 242 QGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGI 301
QGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGI
Sbjct: 173 QGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGI 232
Query: 302 LFIILRKRQGSRGAMGHYVLAERE 325
LFIILRKRQGSRGAMGHYVLAERE
Sbjct: 233 LFIILRKRQGSRGAMGHYVLAERE 256
Score = 174 bits (440), Expect = 1e-43
Identities = 89/113 (78%), Positives = 89/113 (78%), Gaps = 23/113 (20%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLL-----------------------PLGYVDDQLFVF 37
MGPRARPALLLLMLLQTAVLQGRLL LGYVDDQLFVF
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
Query: 38 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 90
YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK
Sbjct: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
>gi|21040355 hemochromatosis protein isoform 10 precursor [Homo
sapiens]
Length = 168
Score = 295 bits (756), Expect = 3e-80
Identities = 142/143 (99%), Positives = 143/143 (100%)
Query: 183 VPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 242
+PPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ
Sbjct: 26 LPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQ 85
Query: 243 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL 302
GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL
Sbjct: 86 GWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGIL 145
Query: 303 FIILRKRQGSRGAMGHYVLAERE 325
FIILRKRQGSRGAMGHYVLAERE
Sbjct: 146 FIILRKRQGSRGAMGHYVLAERE 168
Score = 50.1 bits (118), Expect = 3e-06
Identities = 25/25 (100%), Positives = 25/25 (100%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLL 25
MGPRARPALLLLMLLQTAVLQGRLL
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLL 25
>gi|21040341 hemochromatosis protein isoform 3 precursor [Homo
sapiens]
Length = 242
Score = 271 bits (694), Expect = 4e-73
Identities = 131/135 (97%), Positives = 132/135 (97%)
Query: 191 HHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVP 250
+H S VTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVP
Sbjct: 108 NHNHSKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVP 167
Query: 251 PGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ 310
PGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ
Sbjct: 168 PGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQ 227
Query: 311 GSRGAMGHYVLAERE 325
GSRGAMGHYVLAERE
Sbjct: 228 GSRGAMGHYVLAERE 242
Score = 174 bits (440), Expect = 1e-43
Identities = 89/113 (78%), Positives = 89/113 (78%), Gaps = 23/113 (20%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLL-----------------------PLGYVDDQLFVF 37
MGPRARPALLLLMLLQTAVLQGRLL LGYVDDQLFVF
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVF 60
Query: 38 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 90
YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK
Sbjct: 61 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSK 113
>gi|4504417 major histocompatibility complex, class I-related [Homo
sapiens]
Length = 341
Score = 207 bits (526), Expect = 1e-53
Identities = 110/286 (38%), Positives = 165/286 (57%), Gaps = 5/286 (1%)
Query: 25 LPLGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIME 84
+ +GYVD YD +R+ EPR PW++ ++ W + +Q L+GW MF V+ +
Sbjct: 45 ISVGYVDSHPITTYDSVTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQR 104
Query: 85 NHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKL 144
++NHS SHT Q ++GCE+ ED ST G+ +Y YDGQD L F DTL W A + A K
Sbjct: 105 HYNHSG-SHTYQRMIGCELLEDGSTTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQ 163
Query: 145 EWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVT-SSVTTLRCR 203
WE ++ + +LE +C A L++ LE G+ L + PPLV+V T VT L C+
Sbjct: 164 AWEANQHELLYQKNWLEEECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCK 223
Query: 204 ALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEH 263
A +YP I M W+K+ + + +E + D+LP+GDGTYQ W ++ + P Y+C VEH
Sbjct: 224 AHGFYPPEIYMTWMKNGEEI-VQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEH 282
Query: 264 PGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR 309
G+ L V E S + LV+ +SG V V++L G+ ++ R+R
Sbjct: 283 CGVHMVLQVPQE-SETIPLVMKAVSGSIVLVIVL-AGVGVLVWRRR 326
>gi|17986001 major histocompatibility complex, class I, B precursor
[Homo sapiens]
Length = 362
Score = 201 bits (512), Expect = 6e-52
Identities = 112/303 (36%), Positives = 170/303 (56%), Gaps = 9/303 (2%)
Query: 23 RLLPLGYVDDQLFVFYDHE--SRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFW 80
R + +GYVDD FV +D + S R EPR PW+ + W + +Q K
Sbjct: 45 RFISVGYVDDTQFVRFDSDAASPREEPRAPWIEQE-GPEYWDRNTQIYKAQAQTDRESLR 103
Query: 81 TIMENHNHSKE-SHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPR 138
+ +N S+ SHTLQ + GC++ D G+ +Y YDG+D++ D W AA+
Sbjct: 104 NLRGYYNQSEAGSHTLQSMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTA 163
Query: 139 AWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSV 197
A T+ +WE + A Q RAYLE +C L++ LE G+ L++ PP VTHH ++
Sbjct: 164 AQITQRKWEAAR-EAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHE 222
Query: 198 TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRY 257
TLRC AL +YP IT+ W +D + ++ E + P GD T+Q W + VP GEEQRY
Sbjct: 223 ATLRCWALGFYPAEITLTWQRDGEDQ-TQDTELVETRPAGDRTFQKWAAVVVPSGEEQRY 281
Query: 258 TCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 316
TC V+H GL +PL + WEPS T+ ++G+++G+AV V++ ++ ++ +R+ S G
Sbjct: 282 TCHVQHEGLPKPLTLRWEPSSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKG 341
Query: 317 GHY 319
G Y
Sbjct: 342 GSY 344
>gi|24797067 major histocompatibility complex, class I, A precursor
[Homo sapiens]
Length = 365
Score = 199 bits (507), Expect = 2e-51
Identities = 111/306 (36%), Positives = 172/306 (56%), Gaps = 9/306 (2%)
Query: 23 RLLPLGYVDDQLFVFYDHE--SRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFW 80
R + +GYVDD FV +D + S+R+EPR PW+ + W Q ++++K VD
Sbjct: 45 RFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQE-GPEYWDQETRNVKAQSQTDRVDLG 103
Query: 81 TIMENHNHSKE-SHTLQVILGCEMQEDNS-TEGYWKYGYDGQDHLEFCPDTLDWRAAEPR 138
T+ +N S+ SHT+Q++ GC++ D GY + YDG+D++ D W AA+
Sbjct: 104 TLRGYYNQSEAGSHTIQIMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMA 163
Query: 139 AWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSV 197
A TK +WE A Q RAYL+ C L++ LE G+ L + PP +THH ++
Sbjct: 164 AQITKRKWEAAH-EAEQLRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHE 222
Query: 198 TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRY 257
TLRC AL +YP IT+ W +D + ++ E + P GDGT+Q W + VP GEEQRY
Sbjct: 223 ATLRCWALGFYPAEITLTWQRDGEDQ-TQDTELVETRPAGDGTFQKWAAVVVPSGEEQRY 281
Query: 258 TCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 316
TC V+H GL +PL + WE S T+ ++G+I+G+ + ++ ++ ++ +R+ S
Sbjct: 282 TCHVQHEGLPKPLTLRWELSSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKG 341
Query: 317 GHYVLA 322
G Y A
Sbjct: 342 GSYTQA 347
>gi|89063265 PREDICTED: similar to MHC class I antigen [Homo
sapiens]
Length = 366
Score = 197 bits (501), Expect = 1e-50
Identities = 114/300 (38%), Positives = 168/300 (56%), Gaps = 9/300 (3%)
Query: 23 RLLPLGYVDDQLFVFYDHESR--RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFW 80
R + +GYVDD FV +D +S R EPR PW+ + W + ++ +K F V
Sbjct: 58 RFISVGYVDDTQFVRFDSDSANPREEPRAPWMEQE-GPEYWDEQTRIVKDTAQSFRVGLN 116
Query: 81 TIMENHNHSKE-SHTLQVILGCEMQEDNS-TEGYWKYGYDGQDHLEFCPDTLDWRAAEPR 138
T+ +N S+ SHTLQ++ GC++ D G+ + YDG+D++ D W AA+
Sbjct: 117 TLRGYYNQSEAGSHTLQLMYGCDVGPDGRFLRGFMQDAYDGRDYIALNEDLRSWTAADTA 176
Query: 139 AWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSV 197
A TK + E RQ R YLE C L++ LE G+ L + PP VTHH ++
Sbjct: 177 AQITKRKREAAGAAERQ-RNYLEGRCVEGLRRYLETGKDALLRADPPKAHVTHHPISERE 235
Query: 198 TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRY 257
TLRC AL +YP+ I++ W ++ + ++ E + P+GDGT+Q W L VP GEEQRY
Sbjct: 236 VTLRCWALGFYPEEISLTWQREGEDQ-TQDMELVETRPSGDGTFQKWAALVVPSGEEQRY 294
Query: 258 TCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMG 317
TC+V+H GL +PL + WEP + L++G+I G+ + VV L G + I +KR G G G
Sbjct: 295 TCRVQHEGLQEPLTLRWEPPQTSFLIMGIIVGLVLLVVALVAGAV-IWRKKRSGREGREG 353
>gi|52630342 major histocompatibility complex, class I, C precursor
[Homo sapiens]
Length = 366
Score = 194 bits (494), Expect = 7e-50
Identities = 114/301 (37%), Positives = 166/301 (55%), Gaps = 9/301 (2%)
Query: 23 RLLPLGYVDDQLFVFYDHE--SRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFW 80
R + +GYVDD FV +D + S R EPR PWV + W + +Q K V
Sbjct: 45 RFISVGYVDDTQFVRFDSDAASPRGEPRAPWVEQE-GPEYWDRETQKYKRQAQADRVSLR 103
Query: 81 TIMENHNHSKE-SHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPR 138
+ +N S++ SHTLQ + GC++ D GY + YDG+D++ D W AA+
Sbjct: 104 NLRGYYNQSEDGSHTLQRMSGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAADTA 163
Query: 139 AWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSS-V 197
A T+ + E + A Q RAYLE C L++ LE G+ L + PP VTHH S
Sbjct: 164 AQITQRKLEAARA-AEQLRAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHE 222
Query: 198 TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRY 257
TLRC AL +YP IT+ W +D + ++ E + P GDGT+Q W + VP G+EQRY
Sbjct: 223 ATLRCWALGFYPAEITLTWQRDGEDQ-TQDTELVETRPAGDGTFQKWAAVVVPSGQEQRY 281
Query: 258 TCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 316
TC ++H GL +PL + WEPS T+ ++G+++G+AV VV+ +G + + R+ S G
Sbjct: 282 TCHMQHEGLQEPLTLSWEPSSQPTIPIMGIVAGLAVLVVLAVLGAVVTAMMCRRKSSGGK 341
Query: 317 G 317
G
Sbjct: 342 G 342
>gi|4504415 major histocompatibility complex, class I, G precursor
[Homo sapiens]
Length = 338
Score = 191 bits (485), Expect = 8e-49
Identities = 108/296 (36%), Positives = 166/296 (56%), Gaps = 9/296 (3%)
Query: 23 RLLPLGYVDDQLFVFYDHESR--RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFW 80
R + +GYVDD FV +D +S R+EPR PWV + W + +++ K ++
Sbjct: 45 RFIAMGYVDDTQFVRFDSDSACPRMEPRAPWVEQE-GPEYWEEETRNTKAHAQTDRMNLQ 103
Query: 81 TIMENHNHSK-ESHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPR 138
T+ +N S+ SHTLQ ++GC++ D GY +Y YDG+D+L D W AA+
Sbjct: 104 TLRGYYNQSEASSHTLQWMIGCDLGSDGRLLRGYEQYAYDGKDYLALNEDLRSWTAADTA 163
Query: 139 AWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSV 197
A +K + E + A Q RAYLE C L + LE G+ +L + PP VTHH V
Sbjct: 164 AQISKRKCEAANV-AEQRRAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFDYE 222
Query: 198 TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRY 257
TLRC AL +YP I + W +D + ++ E + P GDGT+Q W + VP GEEQRY
Sbjct: 223 ATLRCWALGFYPAEIILTWQRDGEDQ-TQDVELVETRPAGDGTFQKWAAVVVPSGEEQRY 281
Query: 258 TCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGS 312
TC V+H GL +PL++ W+ S T+ ++G+++G+ V ++ + +L +++ S
Sbjct: 282 TCHVQHEGLPEPLMLRWKQSSLPTIPIMGIVAGLVVLAAVVTGAAVAAVLWRKKSS 337
>gi|149158702 major histocompatibility complex, class I, F isoform 1
precursor [Homo sapiens]
Length = 442
Score = 189 bits (479), Expect = 4e-48
Identities = 108/303 (35%), Positives = 166/303 (54%), Gaps = 9/303 (2%)
Query: 23 RLLPLGYVDDQLFVFYDHESR--RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFW 80
R + + YVDD F+ +D ++ R+EPR PWV Q W + K V
Sbjct: 42 RYIAVEYVDDTQFLRFDSDAAIPRMEPREPWVEQE-GPQYWEWTTGYAKANAQTDRVALR 100
Query: 81 TIMENHNHSKE-SHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPR 138
++ +N S+ SHTLQ + GC+M D GY ++ YDG+D++ D W AA+
Sbjct: 101 NLLRRYNQSEAGSHTLQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTV 160
Query: 139 AWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSV 197
A T+ +E + A + R YLE +C L++ LE G+ L + PP V HH ++
Sbjct: 161 AQITQRFYEAEEY-AEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHE 219
Query: 198 TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRY 257
TLRC AL +YP IT+ W +D + ++ E + P GDGT+Q W + VPPGEEQRY
Sbjct: 220 ATLRCWALGFYPAEITLTWQRDGEEQ-TQDTELVETRPAGDGTFQKWAAVVVPPGEEQRY 278
Query: 258 TCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 316
TC V+H GL QPLI+ WE SP T+ ++G+++G+ V ++ ++ ++ +++ S
Sbjct: 279 TCHVQHEGLPQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNR 338
Query: 317 GHY 319
G Y
Sbjct: 339 GSY 341
>gi|149158698 major histocompatibility complex, class I, F isoform 2
precursor [Homo sapiens]
Length = 346
Score = 189 bits (479), Expect = 4e-48
Identities = 108/303 (35%), Positives = 166/303 (54%), Gaps = 9/303 (2%)
Query: 23 RLLPLGYVDDQLFVFYDHESR--RVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFW 80
R + + YVDD F+ +D ++ R+EPR PWV Q W + K V
Sbjct: 42 RYIAVEYVDDTQFLRFDSDAAIPRMEPREPWVEQE-GPQYWEWTTGYAKANAQTDRVALR 100
Query: 81 TIMENHNHSKE-SHTLQVILGCEMQEDNST-EGYWKYGYDGQDHLEFCPDTLDWRAAEPR 138
++ +N S+ SHTLQ + GC+M D GY ++ YDG+D++ D W AA+
Sbjct: 101 NLLRRYNQSEAGSHTLQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTV 160
Query: 139 AWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSV 197
A T+ +E + A + R YLE +C L++ LE G+ L + PP V HH ++
Sbjct: 161 AQITQRFYEAEEY-AEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHE 219
Query: 198 TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRY 257
TLRC AL +YP IT+ W +D + ++ E + P GDGT+Q W + VPPGEEQRY
Sbjct: 220 ATLRCWALGFYPAEITLTWQRDGEEQ-TQDTELVETRPAGDGTFQKWAAVVVPPGEEQRY 278
Query: 258 TCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 316
TC V+H GL QPLI+ WE SP T+ ++G+++G+ V ++ ++ ++ +++ S
Sbjct: 279 TCHVQHEGLPQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNR 338
Query: 317 GHY 319
G Y
Sbjct: 339 GSY 341
>gi|62912479 major histocompatibility complex, class I, E precursor
[Homo sapiens]
Length = 358
Score = 188 bits (478), Expect = 5e-48
Identities = 108/307 (35%), Positives = 170/307 (55%), Gaps = 9/307 (2%)
Query: 23 RLLPLGYVDDQLFVFYDHE--SRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFW 80
R + +GYVDD FV +D++ S R+ PR PW+ S+ W + ++S + +F V+
Sbjct: 42 RFISVGYVDDTQFVRFDNDAASPRMVPRAPWMEQE-GSEYWDRETRSARDTAQIFRVNLR 100
Query: 81 TIMENHNHSKE-SHTLQVILGCEMQEDNS-TEGYWKYGYDGQDHLEFCPDTLDWRAAEPR 138
T+ +N S+ SHTLQ + GCE+ D GY ++ YDG+D+L D W A +
Sbjct: 101 TLRGYYNQSEAGSHTLQWMHGCELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTA 160
Query: 139 AWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHH-VTSSV 197
A ++ + A RAYLE C L + LE G+ L PP VTHH ++
Sbjct: 161 AQISEQK-SNDASEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHE 219
Query: 198 TTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRY 257
TLRC AL +YP IT+ W +D + ++ E + P GDGT+Q W + VP GEEQRY
Sbjct: 220 ATLRCWALGFYPAEITLTWQQDGEG-HTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRY 278
Query: 258 TCQVEHPGLDQPLIVIWEPSPSGTL-VIGVISGIAVFVVILFIGILFIILRKRQGSRGAM 316
TC V+H GL +P+ + W+P+ T+ ++G+I+G+ + ++ ++ ++ +++ S G
Sbjct: 279 TCHVQHEGLPEPVTLRWKPASQPTIPIVGIIAGLVLLGSVVSGAVVAAVIWRKKSSGGKG 338
Query: 317 GHYVLAE 323
G Y AE
Sbjct: 339 GSYSKAE 345
>gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]
Length = 298
Score = 178 bits (452), Expect = 5e-45
Identities = 95/255 (37%), Positives = 142/255 (55%), Gaps = 10/255 (3%)
Query: 27 LGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENH 86
LG ++D F Y+ + R+ +P W + W Q SQ K + +F I+E +
Sbjct: 50 LGSLNDLQFFRYNSKDRKSQPMGLWRQVE-GMEDWKQDSQLQKAREDIFMETLKDIVEYY 108
Query: 87 NHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEW 146
N S SH LQ GCE++ + S+ +WKY YDG+D++EF + W +P A TK +W
Sbjct: 109 NDSNGSHVLQGRFGCEIENNRSSGAFWKYYYDGKDYIEFNKEIPAWVPFDPAAQITKQKW 168
Query: 147 ERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVT-HHVTSSVTTLRCRAL 205
E + ++ +AYLE +CPA L++ L+ + +LD+Q PP V VT H L+C A
Sbjct: 169 EAEPVYVQRAKAYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPGEKKKLKCLAY 228
Query: 206 NYYPQNITMKWLKDKQPMDAKEFEPK---DVLPNGDGTYQGWITLAVPPGEEQRYTCQVE 262
++YP I + W + + EP+ DVL NG+GTYQ W+ +AVPP + Y+C V+
Sbjct: 229 DFYPGKIDVHWTRAGEVQ-----EPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQ 283
Query: 263 HPGLDQPLIVIWEPS 277
H L QPL+V WE S
Sbjct: 284 HSSLAQPLVVPWEAS 298
>gi|167857788 MHC class I polypeptide-related sequence B [Homo
sapiens]
Length = 383
Score = 137 bits (346), Expect = 1e-32
Identities = 88/284 (30%), Positives = 145/284 (51%), Gaps = 23/284 (8%)
Query: 11 LLMLLQTAVLQGRLLPLGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKG 70
L++L Q +Q L G++D Q F+ YD + RR +P+ W + + ++ W ++ L
Sbjct: 32 LMVLSQDGSVQSGFLAEGHLDGQPFLRYDRQKRRAKPQGQWAENVLGAKTWDTETEDL-- 89
Query: 71 WDHMFTVDFWTIMENHNHSKES----HTLQVILGCEMQEDNSTEGYWKYGYDGQ----DH 122
T + + H K+ H+LQ I CE+ ED+ST G + YDG+ +
Sbjct: 90 -----TENGQDLRRTLTHIKDQKGGLHSLQEIRVCEIHEDSSTRGSRHFYYDGELFLSQN 144
Query: 123 LEFCPDTLDWRA-AEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQ 181
LE T+ + A+ A W+ ++ + + ++ DC +LQ+ L+ G + +
Sbjct: 145 LETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRAMQADCLQKLQRYLKSGVAIR-R 203
Query: 182 QVPPLVKVT-HHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGT 240
VPP+V VT V+ T+ CRA ++YP+NIT+ W +D + + DVLP+G+GT
Sbjct: 204 TVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVLPDGNGT 263
Query: 241 YQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVI 284
YQ W+ + GEEQR+TC +EH G P PSG ++
Sbjct: 264 YQTWVATRIRQGEEQRFTCYMEHSGNHGT-----HPVPSGKALV 302
>gi|4557751 MHC class I polypeptide-related sequence A [Homo
sapiens]
Length = 383
Score = 130 bits (328), Expect = 1e-30
Identities = 93/316 (29%), Positives = 149/316 (47%), Gaps = 28/316 (8%)
Query: 2 GPRARPALL---LLMLLQTAVLQGRLLPLGYVDDQLFVFYDHESRRVEPRTPWVSSRISS 58
G A P L L +L +Q L ++D Q F+ D + R +P+ W + +
Sbjct: 20 GAAAEPHSLRYNLTVLSWDGSVQSGFLTEVHLDGQPFLRCDRQKCRAKPQGQWAEDVLGN 79
Query: 59 QMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYD 118
+ W + ++ L G + T+ + + H+LQ I CE+ EDNST + YD
Sbjct: 80 KTWDRETRDLTGNGKDLRM---TLAHIKDQKEGLHSLQEIRVCEIHEDNSTRSSQHFYYD 136
Query: 119 GQDHLEFCPDTLDWRA-----AEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLE 173
G+ L +T +W A+ A + + ++ + + + DC +L++ L+
Sbjct: 137 GELFLSQNLETKEWTMPQSSRAQTLAMNVRNFLKEDAMKTKTHYHAMHADCLQELRRYLK 196
Query: 174 LGRGVLDQQVPPLVKVTHHVTSSVT-TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKD 232
G VL + VPP+V VT S T+ CRA +YP NIT+ W +D + + D
Sbjct: 197 SGV-VLRRTVPPMVNVTRSEASEGNITVTCRASGFYPWNITLSWRQDGVSLSHDTQQWGD 255
Query: 233 VLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSG----------TL 282
VLP+G+GTYQ W+ + GEEQR+TC +EH G P PSG T
Sbjct: 256 VLPDGNGTYQTWVATRICQGEEQRFTCYMEHSGNHST-----HPVPSGKVLVLQSHWQTF 310
Query: 283 VIGVISGIAVFVVILF 298
+ ++ A+FV+I+F
Sbjct: 311 HVSAVAAAAIFVIIIF 326
>gi|209862839 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 119 bits (297), Expect = 5e-27
Identities = 77/277 (27%), Positives = 132/277 (47%), Gaps = 10/277 (3%)
Query: 28 GYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHN 87
G++ Q ++ Y+ EP WV S W + + L+ + +F F +
Sbjct: 51 GWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKAL----- 105
Query: 88 HSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWE 147
K +TLQ +LGCE+ DN++ K+ +G++ + F W P A W+
Sbjct: 106 GGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQ 165
Query: 148 RHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTS-SVTTLRCRALN 206
+ A + +L CP +L++ LE GRG L+ + PP +++ +S + L C A +
Sbjct: 166 QQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFS 225
Query: 207 YYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGL 266
+YP + +++L++ + D PN DG++ +L V G+E Y C V+H GL
Sbjct: 226 FYPPELQLRFLRNGLAAGTGQ---GDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGL 282
Query: 267 DQPLIVIWE-PSPSGTLVIGVISGIAVFVVILFIGIL 302
QPL V E P+ S LV+G++ G+ + G L
Sbjct: 283 AQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGAL 319
>gi|4758346 Fc fragment of IgG, receptor, transporter, alpha [Homo
sapiens]
Length = 365
Score = 119 bits (297), Expect = 5e-27
Identities = 77/277 (27%), Positives = 132/277 (47%), Gaps = 10/277 (3%)
Query: 28 GYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHN 87
G++ Q ++ Y+ EP WV S W + + L+ + +F F +
Sbjct: 51 GWLGPQQYLSYNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKAL----- 105
Query: 88 HSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWE 147
K +TLQ +LGCE+ DN++ K+ +G++ + F W P A W+
Sbjct: 106 GGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQ 165
Query: 148 RHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTS-SVTTLRCRALN 206
+ A + +L CP +L++ LE GRG L+ + PP +++ +S + L C A +
Sbjct: 166 QQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFS 225
Query: 207 YYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGL 266
+YP + +++L++ + D PN DG++ +L V G+E Y C V+H GL
Sbjct: 226 FYPPELQLRFLRNGLAAGTGQ---GDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGL 282
Query: 267 DQPLIVIWE-PSPSGTLVIGVISGIAVFVVILFIGIL 302
QPL V E P+ S LV+G++ G+ + G L
Sbjct: 283 AQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGAL 319
>gi|21040357 hemochromatosis protein isoform 11 precursor [Homo
sapiens]
Length = 76
Score = 99.0 bits (245), Expect = 5e-21
Identities = 50/51 (98%), Positives = 51/51 (100%)
Query: 275 EPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 325
+PSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
Sbjct: 26 QPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE 76
Score = 50.1 bits (118), Expect = 3e-06
Identities = 25/25 (100%), Positives = 25/25 (100%)
Query: 1 MGPRARPALLLLMLLQTAVLQGRLL 25
MGPRARPALLLLMLLQTAVLQGRLL
Sbjct: 1 MGPRARPALLLLMLLQTAVLQGRLL 25
>gi|239740918 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 1 [Homo sapiens]
Length = 281
Score = 88.2 bits (217), Expect = 9e-18
Identities = 66/218 (30%), Positives = 103/218 (47%), Gaps = 12/218 (5%)
Query: 107 NSTE---GYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERD 163
N TE G +Y Y+ +++ F D +RA P P W K + RA L+
Sbjct: 51 NGTERVRGVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTV 110
Query: 164 CPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVT---TLRCRALNYYPQNITMKWLKDK 220
C Q LEL R L ++V P V ++ T ++ L C ++YP I ++W ++
Sbjct: 111 CRHNYQ--LEL-RTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRND 167
Query: 221 QPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSG 280
Q + ++ NGD T+Q + L + P YTC VEHP L P+IV W + S
Sbjct: 168 QE-ETTGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWR-AQSE 225
Query: 281 TLVIGVISGIAVFVV-ILFIGILFIILRKRQGSRGAMG 317
+ ++SGI FV+ ++F+G+ II + Q G
Sbjct: 226 SAQSKMLSGIGGFVLGLIFLGLGLIIHHRSQKGEEPQG 263
>gi|4502649 CD1D antigen precursor [Homo sapiens]
Length = 335
Score = 88.2 bits (217), Expect = 9e-18
Identities = 77/289 (26%), Positives = 127/289 (43%), Gaps = 30/289 (10%)
Query: 38 YDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTL-- 95
+ ++S V PW S Q W L + + FT D + E + S+ L
Sbjct: 58 WSNDSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRD---VKEFAKMLRLSYPLEL 114
Query: 96 QVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKL--------EWE 147
QV GCE+ N++ ++ + G+D L F W + L +W
Sbjct: 115 QVSAGCEVHPGNASNNFFHVAFQGKDILSF--QGTSWEPTQEAPLWVNLAIQVLNQDKWT 172
Query: 148 RHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLR--CRAL 205
R ++ N CP + LLE G+ L +QV P ++ + L C
Sbjct: 173 RETVQWLLNGT-----CPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVS 227
Query: 206 NYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPG 265
+YP+ + +KW++ +Q + P D+LPN D T+ TL V GE +C+V+H
Sbjct: 228 GFYPKPVWVKWMRGEQEQQGTQ--PGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSS 285
Query: 266 LD-QPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILR-KRQGS 312
L+ Q +++ W S + +G+I+ +AV +LF+ I+ R KRQ S
Sbjct: 286 LEGQDIVLYWGGSYTS---MGLIA-LAVLACLLFLLIVGFTSRFKRQTS 330
>gi|239740920 PREDICTED: similar to major histocompatibility
complex, class II, DQ beta 1 isoform 2 [Homo sapiens]
Length = 261
Score = 87.8 bits (216), Expect = 1e-17
Identities = 65/211 (30%), Positives = 102/211 (48%), Gaps = 12/211 (5%)
Query: 107 NSTE---GYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERD 163
N TE G +Y Y+ +++ F D +RA P P W K + RA L+
Sbjct: 51 NGTERVRGVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRAELDTV 110
Query: 164 CPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVT---TLRCRALNYYPQNITMKWLKDK 220
C Q LEL R L ++V P V ++ T ++ L C ++YP I ++W ++
Sbjct: 111 CRHNYQ--LEL-RTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRND 167
Query: 221 QPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSG 280
Q + ++ NGD T+Q + L + P YTC VEHP L P+IV W + S
Sbjct: 168 QE-ETTGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWR-AQSE 225
Query: 281 TLVIGVISGIAVFVV-ILFIGILFIILRKRQ 310
+ ++SGI FV+ ++F+G+ II + Q
Sbjct: 226 SAQSKMLSGIGGFVLGLIFLGLGLIIHHRSQ 256
>gi|150418002 major histocompatibility complex, class II, DQ beta 1
precursor [Homo sapiens]
Length = 261
Score = 85.5 bits (210), Expect = 6e-17
Identities = 57/201 (28%), Positives = 97/201 (48%), Gaps = 9/201 (4%)
Query: 114 KYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLE 173
+Y Y+ +++ F D +RA P+ P W K RA L+ C +
Sbjct: 61 RYIYNREEYARFDSDVGVYRAVTPQGRPDAEYWNSQKEVLEGTRAELDTVCRHNYEVAF- 119
Query: 174 LGRGVLDQQVPPLVKVTHHVTSSVT---TLRCRALNYYPQNITMKWLKDKQPMDAKEFEP 230
RG+L ++V P V ++ T ++ L C ++YP I ++W ++ Q A
Sbjct: 120 --RGILQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPGQIKVRWFRNDQEETAGVVST 177
Query: 231 KDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGI 290
++ NGD T+Q + L + P YTC VEHP L P+ V W + S + ++SG+
Sbjct: 178 P-LIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWR-AQSESAQSKMLSGV 235
Query: 291 AVFVV-ILFIGILFIILRKRQ 310
FV+ ++F+G+ II ++ Q
Sbjct: 236 GGFVLGLIFLGLGLIIRQRSQ 256
>gi|169168591 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 isoform 1 [Homo sapiens]
Length = 261
Score = 85.1 bits (209), Expect = 8e-17
Identities = 64/211 (30%), Positives = 101/211 (47%), Gaps = 12/211 (5%)
Query: 107 NSTE---GYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERD 163
N TE G +Y Y+ +++ F D +RA P P W K + RA ++
Sbjct: 51 NGTERVRGVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYWNSQKEVLERTRASVDTV 110
Query: 164 CPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVT---TLRCRALNYYPQNITMKWLKDK 220
C Q LEL R L ++V P V ++ T ++ L C ++YP I ++W ++
Sbjct: 111 CRHNYQ--LEL-RTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRND 167
Query: 221 QPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSG 280
Q A ++ NGD T+Q + L + P YTC VEHP L P+ V W + S
Sbjct: 168 QEETAGVVSTP-LIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWR-AQSE 225
Query: 281 TLVIGVISGIAVFVV-ILFIGILFIILRKRQ 310
+ ++SGI FV+ ++F+G+ II + Q
Sbjct: 226 SAQSKMLSGIGGFVLGLIFLGLGLIIHHRSQ 256
>gi|239748788 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 isoform 2 [Homo sapiens]
Length = 281
Score = 81.3 bits (199), Expect = 1e-15
Identities = 60/205 (29%), Positives = 97/205 (47%), Gaps = 9/205 (4%)
Query: 117 YDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGR 176
Y+ ++ + F D ++RA P W K + RA ++R C Q LEL R
Sbjct: 64 YNREEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQ--LEL-R 120
Query: 177 GVLDQQVPPLVKVTHHVTSSVT---TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDV 233
L ++V P V ++ T ++ L C ++YP I ++W ++ Q A +
Sbjct: 121 TTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTP-L 179
Query: 234 LPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVF 293
+ NGD T+Q + L + P YTC VEHP L P+ V W + S + ++SGI F
Sbjct: 180 IRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWR-AQSESAQSKMLSGIGGF 238
Query: 294 VV-ILFIGILFIILRKRQGSRGAMG 317
V+ ++F+G+ II + Q G
Sbjct: 239 VLGLIFLGLGLIIHHRSQKGEEPQG 263
>gi|239740863 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 [Homo sapiens]
Length = 281
Score = 81.3 bits (199), Expect = 1e-15
Identities = 60/205 (29%), Positives = 97/205 (47%), Gaps = 9/205 (4%)
Query: 117 YDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGR 176
Y+ ++ + F D ++RA P W K + RA ++R C Q LEL R
Sbjct: 64 YNREEIVRFDSDVGEFRAVTLLGLPAAEYWNSQKDILERKRAAVDRVCRHNYQ--LEL-R 120
Query: 177 GVLDQQVPPLVKVTHHVTSSVT---TLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDV 233
L ++V P V ++ T ++ L C ++YP I ++W ++ Q A +
Sbjct: 121 TTLQRRVEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTP-L 179
Query: 234 LPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVF 293
+ NGD T+Q + L + P YTC VEHP L P+ V W + S + ++SGI F
Sbjct: 180 IRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWR-AQSESAQSKMLSGIGGF 238
Query: 294 VV-ILFIGILFIILRKRQGSRGAMG 317
V+ ++F+G+ II + Q G
Sbjct: 239 VLGLIFLGLGLIIHHRSQKGEEPQG 263
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.444
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,723,768
Number of Sequences: 37866
Number of extensions: 646399
Number of successful extensions: 1763
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 89
Number of HSP's successfully gapped in prelim test: 38
Number of HSP's that attempted gapping in prelim test: 1521
Number of HSP's gapped (non-prelim): 152
length of query: 325
length of database: 18,247,518
effective HSP length: 102
effective length of query: 223
effective length of database: 14,385,186
effective search space: 3207896478
effective search space used: 3207896478
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.