BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|206597543 hypothetical protein LOC118461 isoform 1 [Homo sapiens] (1435 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|206597543 hypothetical protein LOC118461 isoform 1 [Homo sapi... 2944 0.0 gi|49574498 hypothetical protein LOC118461 isoform 2 [Homo sapiens] 1424 0.0 gi|238908524 hypothetical protein LOC389333 [Homo sapiens] 84 1e-15 gi|169167062 PREDICTED: hypothetical protein LOC285556 [Homo sap... 71 7e-12 gi|113416182 PREDICTED: hypothetical protein LOC285556 [Homo sap... 71 7e-12 gi|113415686 PREDICTED: hypothetical protein LOC285556 [Homo sap... 71 7e-12 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 56 2e-07 gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 55 6e-07 gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 54 1e-06 gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 53 2e-06 gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 53 2e-06 gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 53 2e-06 gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 53 2e-06 gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 53 2e-06 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 51 7e-06 gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit... 50 1e-05 gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 50 1e-05 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 47 2e-04 gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 46 2e-04 gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 45 4e-04 gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 45 4e-04 gi|163965366 nascent polypeptide-associated complex alpha subuni... 45 5e-04 gi|33667044 ABI gene family, member 3 (NESH) binding protein [Ho... 44 0.001 gi|18079216 CASK interacting protein 1 [Homo sapiens] 44 0.001 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 43 0.002 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 43 0.002 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 43 0.002 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 43 0.002 gi|148806908 fibronectin type III domain containing 1 [Homo sapi... 43 0.002 gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 43 0.002 >gi|206597543 hypothetical protein LOC118461 isoform 1 [Homo sapiens] Length = 1435 Score = 2944 bits (7633), Expect = 0.0 Identities = 1435/1435 (100%), Positives = 1435/1435 (100%) Query: 1 MMQGNKKCTDAFSDSSSIGSVLDDADREVSSLTDRAFRSLCISEDTSFHDSYLAVSPDIT 60 MMQGNKKCTDAFSDSSSIGSVLDDADREVSSLTDRAFRSLCISEDTSFHDSYLAVSPDIT Sbjct: 1 MMQGNKKCTDAFSDSSSIGSVLDDADREVSSLTDRAFRSLCISEDTSFHDSYLAVSPDIT 60 Query: 61 RQVFGTFHQRTVGHTQRKSGIWSQLPSQGTEHSGWAATFQQLPKYVQGEEKYPKTSPPPT 120 RQVFGTFHQRTVGHTQRKSGIWSQLPSQGTEHSGWAATFQQLPKYVQGEEKYPKTSPPPT Sbjct: 61 RQVFGTFHQRTVGHTQRKSGIWSQLPSQGTEHSGWAATFQQLPKYVQGEEKYPKTSPPPT 120 Query: 121 PVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTESQRCESRPTASKPPALKNPPKFAPLP 180 PVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTESQRCESRPTASKPPALKNPPKFAPLP Sbjct: 121 PVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTESQRCESRPTASKPPALKNPPKFAPLP 180 Query: 181 ENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQESSKNPEMACHGSSSFLPAAN 240 ENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQESSKNPEMACHGSSSFLPAAN Sbjct: 181 ENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQESSKNPEMACHGSSSFLPAAN 240 Query: 241 DTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENSAFESWNAHQPKLLERKDTAGTVPES 300 DTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENSAFESWNAHQPKLLERKDTAGTVPES Sbjct: 241 DTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENSAFESWNAHQPKLLERKDTAGTVPES 300 Query: 301 KAPKHYGDTTLLREPCPPERTVSPCQVQASCSQEENRLAAGALSTSIPWGCRDPGAQVFA 360 KAPKHYGDTTLLREPCPPERTVSPCQVQASCSQEENRLAAGALSTSIPWGCRDPGAQVFA Sbjct: 301 KAPKHYGDTTLLREPCPPERTVSPCQVQASCSQEENRLAAGALSTSIPWGCRDPGAQVFA 360 Query: 361 VEGKAPSSQPDSQEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQ 420 VEGKAPSSQPDSQEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQ Sbjct: 361 VEGKAPSSQPDSQEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQ 420 Query: 421 FSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQE 480 FSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQE Sbjct: 421 FSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQE 480 Query: 481 KEPSECQSRDSYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSN 540 KEPSECQSRDSYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSN Sbjct: 481 KEPSECQSRDSYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSN 540 Query: 541 GVILPNGLEESPPNELSKERPADDPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAKA 600 GVILPNGLEESPPNELSKERPADDPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAKA Sbjct: 541 GVILPNGLEESPPNELSKERPADDPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAKA 600 Query: 601 PFYVNGEAAERSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPGGAT 660 PFYVNGEAAERSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPGGAT Sbjct: 601 PFYVNGEAAERSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPGGAT 660 Query: 661 EKMKTHQLENGLSRSVSQETEPEREAGLQNTHLNQKFFPGPLSPEEEDVFYSDSQSDFMP 720 EKMKTHQLENGLSRSVSQETEPEREAGLQNTHLNQKFFPGPLSPEEEDVFYSDSQSDFMP Sbjct: 661 EKMKTHQLENGLSRSVSQETEPEREAGLQNTHLNQKFFPGPLSPEEEDVFYSDSQSDFMP 720 Query: 721 SLKGKAKFSTSSSDQSFASFDDQQKMWFTENQREDRRKDVSAGDSQKDEKENVMRKDELQ 780 SLKGKAKFSTSSSDQSFASFDDQQKMWFTENQREDRRKDVSAGDSQKDEKENVMRKDELQ Sbjct: 721 SLKGKAKFSTSSSDQSFASFDDQQKMWFTENQREDRRKDVSAGDSQKDEKENVMRKDELQ 780 Query: 781 YCALSNGHACLENRSQGEALQRERESVSGGRTRKASAEEANFRGSWIGENKGTTFSQAKD 840 YCALSNGHACLENRSQGEALQRERESVSGGRTRKASAEEANFRGSWIGENKGTTFSQAKD Sbjct: 781 YCALSNGHACLENRSQGEALQRERESVSGGRTRKASAEEANFRGSWIGENKGTTFSQAKD 840 Query: 841 LTPSPSSASNRHMLFTIKDNTLRATPVIKPIMLPLLRTMSLEDSLSSGHKEEELPRPEWG 900 LTPSPSSASNRHMLFTIKDNTLRATPVIKPIMLPLLRTMSLEDSLSSGHKEEELPRPEWG Sbjct: 841 LTPSPSSASNRHMLFTIKDNTLRATPVIKPIMLPLLRTMSLEDSLSSGHKEEELPRPEWG 900 Query: 901 EDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAPKGNFPS 960 EDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAPKGNFPS Sbjct: 901 EDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAPKGNFPS 960 Query: 961 MPLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIPTIALPEGDIEDQPPPWQP 1020 MPLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIPTIALPEGDIEDQPPPWQP Sbjct: 961 MPLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIPTIALPEGDIEDQPPPWQP 1020 Query: 1021 ENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESS 1080 ENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESS Sbjct: 1021 ENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESS 1080 Query: 1081 QAPGGPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPR 1140 QAPGGPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPR Sbjct: 1081 QAPGGPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPR 1140 Query: 1141 GSLLDVATSPAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEK 1200 GSLLDVATSPAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEK Sbjct: 1141 GSLLDVATSPAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEK 1200 Query: 1201 HGESQEGKPCPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGG 1260 HGESQEGKPCPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGG Sbjct: 1201 HGESQEGKPCPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGG 1260 Query: 1261 PQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPSSEGASP 1320 PQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPSSEGASP Sbjct: 1261 PQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPSSEGASP 1320 Query: 1321 EPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASAARARTQSVHES 1380 EPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASAARARTQSVHES Sbjct: 1321 EPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASAARARTQSVHES 1380 Query: 1381 GLQLDPGPHGDCTPHSAGQRPHGPPQSPGEEGVEAPGLGIISTDDLEDFATEGIS 1435 GLQLDPGPHGDCTPHSAGQRPHGPPQSPGEEGVEAPGLGIISTDDLEDFATEGIS Sbjct: 1381 GLQLDPGPHGDCTPHSAGQRPHGPPQSPGEEGVEAPGLGIISTDDLEDFATEGIS 1435 >gi|49574498 hypothetical protein LOC118461 isoform 2 [Homo sapiens] Length = 719 Score = 1424 bits (3685), Expect = 0.0 Identities = 692/692 (100%), Positives = 692/692 (100%) Query: 1 MMQGNKKCTDAFSDSSSIGSVLDDADREVSSLTDRAFRSLCISEDTSFHDSYLAVSPDIT 60 MMQGNKKCTDAFSDSSSIGSVLDDADREVSSLTDRAFRSLCISEDTSFHDSYLAVSPDIT Sbjct: 1 MMQGNKKCTDAFSDSSSIGSVLDDADREVSSLTDRAFRSLCISEDTSFHDSYLAVSPDIT 60 Query: 61 RQVFGTFHQRTVGHTQRKSGIWSQLPSQGTEHSGWAATFQQLPKYVQGEEKYPKTSPPPT 120 RQVFGTFHQRTVGHTQRKSGIWSQLPSQGTEHSGWAATFQQLPKYVQGEEKYPKTSPPPT Sbjct: 61 RQVFGTFHQRTVGHTQRKSGIWSQLPSQGTEHSGWAATFQQLPKYVQGEEKYPKTSPPPT 120 Query: 121 PVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTESQRCESRPTASKPPALKNPPKFAPLP 180 PVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTESQRCESRPTASKPPALKNPPKFAPLP Sbjct: 121 PVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTESQRCESRPTASKPPALKNPPKFAPLP 180 Query: 181 ENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQESSKNPEMACHGSSSFLPAAN 240 ENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQESSKNPEMACHGSSSFLPAAN Sbjct: 181 ENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQESSKNPEMACHGSSSFLPAAN 240 Query: 241 DTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENSAFESWNAHQPKLLERKDTAGTVPES 300 DTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENSAFESWNAHQPKLLERKDTAGTVPES Sbjct: 241 DTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENSAFESWNAHQPKLLERKDTAGTVPES 300 Query: 301 KAPKHYGDTTLLREPCPPERTVSPCQVQASCSQEENRLAAGALSTSIPWGCRDPGAQVFA 360 KAPKHYGDTTLLREPCPPERTVSPCQVQASCSQEENRLAAGALSTSIPWGCRDPGAQVFA Sbjct: 301 KAPKHYGDTTLLREPCPPERTVSPCQVQASCSQEENRLAAGALSTSIPWGCRDPGAQVFA 360 Query: 361 VEGKAPSSQPDSQEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQ 420 VEGKAPSSQPDSQEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQ Sbjct: 361 VEGKAPSSQPDSQEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQ 420 Query: 421 FSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQE 480 FSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQE Sbjct: 421 FSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQE 480 Query: 481 KEPSECQSRDSYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSN 540 KEPSECQSRDSYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSN Sbjct: 481 KEPSECQSRDSYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSN 540 Query: 541 GVILPNGLEESPPNELSKERPADDPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAKA 600 GVILPNGLEESPPNELSKERPADDPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAKA Sbjct: 541 GVILPNGLEESPPNELSKERPADDPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAKA 600 Query: 601 PFYVNGEAAERSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPGGAT 660 PFYVNGEAAERSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPGGAT Sbjct: 601 PFYVNGEAAERSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPGGAT 660 Query: 661 EKMKTHQLENGLSRSVSQETEPEREAGLQNTH 692 EKMKTHQLENGLSRSVSQETEPEREAGLQNTH Sbjct: 661 EKMKTHQLENGLSRSVSQETEPEREAGLQNTH 692 >gi|238908524 hypothetical protein LOC389333 [Homo sapiens] Length = 1015 Score = 83.6 bits (205), Expect = 1e-15 Identities = 115/463 (24%), Positives = 166/463 (35%), Gaps = 71/463 (15%) Query: 917 STPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAPKGNFPSMPLVGEGDRVKAPPDA 976 S P T ++ + + D G S E + P P G+ P VG D K P Sbjct: 552 SAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHP----VGTLDADKCPEVL 607 Query: 977 APGLVASNCKSGSA----DSGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFK 1032 PG AS + D KL + P P G P + C EE G + Sbjct: 608 GPGEAASGRPRMAIPRPRDVRKLVKTTYAP--GFPAGAQGSGLPAPPADPCGEE---GGE 662 Query: 1033 SHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPGGPELLPEE 1092 S P GPP S P P P+ + ++SQ P G E Sbjct: 663 SKTQEPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQ-PNGVLRRRAE 721 Query: 1093 PNQASPWASSS-----PARVTRREDLTHALVWEGGSDPLLELSAEDL------RTLSPRG 1141 + A P+ + + RR ++T + G ++ A+ L RT G Sbjct: 722 NSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGG 781 Query: 1142 SLLDVATSPAGTSG-RLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEK 1200 + SP G +G R P + AS P + PK + + A+ + Sbjct: 782 ARSSSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQA-------- 833 Query: 1201 HGESQEGKPCPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGG 1260 P P + PL R P S PP S S+ R+PG Sbjct: 834 --------PLPRE-------PLALAGRTAPAQPRAASAPPT--DRSPQSPSQGARRQPGA 876 Query: 1261 PQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPSSEGASP 1320 PL KVL DP+SG Y+ + P Q +++ +DPE+G+YV+V +P S Sbjct: 877 ----APLG------KVLVDPESGRYYFVEAPRQPRLRVLFDPESGQYVEVLLPPS----- 921 Query: 1321 EPPPPDALAAPYVL-----YPGFQPVPVTALMPLRCSSQLSAP 1358 P PP + P L P + P+P +L P L +P Sbjct: 922 SPGPPHRVYTPLALGLGLYPPAYGPIPSLSLPPSPGPQALGSP 964 Score = 33.1 bits (74), Expect = 2.0 Identities = 39/158 (24%), Positives = 57/158 (36%), Gaps = 34/158 (21%) Query: 959 PSMPLVGEGDRV----KAPPDAAPGL-------VASNCKSGSADSGKLAAPWHIPTIALP 1007 PS P++ + ++ ++P AP L VA + S+ S PW P Sbjct: 453 PSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEPRSSPSPPAFFPWEAP----- 507 Query: 1008 EGDIEDQP-PPW--QPENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGE 1064 D+P W P+ W+ PG F + G L P P P +PG Sbjct: 508 -----DRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELAP------PTPSAPGT 556 Query: 1065 SSACSPAASNIWEESSQAPGG----PELLPEEPNQASP 1098 + + E S A GG PE+ EP + P Sbjct: 557 PEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHP 594 >gi|169167062 PREDICTED: hypothetical protein LOC285556 [Homo sapiens] Length = 1826 Score = 71.2 bits (173), Expect = 7e-12 Identities = 92/346 (26%), Positives = 139/346 (40%), Gaps = 64/346 (18%) Query: 1043 PPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQA---PGGPELLPEEPNQASPW 1099 PP + V + P P P + + +AS+I + A P GP PE P+ A Sbjct: 1406 PPVHKDVERTQPLQPLPPLPSNRNVFTVSASSIQKTGGVAGKFPQGPS--PESPSAAKGI 1463 Query: 1100 ASS-------SPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAG 1152 S SPA +++T+ + GS+ LE S D + L + + Sbjct: 1464 KSQGLRSLKISPATRAPPDEVTNR---KSGSN--LEKSNSDCE------NYLTIPLKGSS 1512 Query: 1153 TSGRLELPAQLERTASKPPAV---PPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKP 1209 +G L S+P A PP + A + S R + + + S +P Sbjct: 1513 AAGEL---------LSRPGASREGPPNSSAATLCSLPPLSARSQVPSSSKGSQVSGTSRP 1563 Query: 1210 C----PEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVH-----RHSVSGFSEPVGRRPGG 1260 P++ +T P P+ P H + PP + V FS P P Sbjct: 1564 AWRTKPDNPRETVAAPPGPQS-PEHPPTTIYHQPPLPFTLQGAQPQVLCFSPPSMPAPA- 1621 Query: 1261 PQSLTPLPAYPATQ--------KVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSI 1312 P + P+P P Q K+L D +G+Y++ D P+Q + +DPETG+YV V + Sbjct: 1622 PAASAPVPTDPFQQAQPQQTQRKMLLDVTTGQYYLVDTPVQPMTRRLFDPETGQYVDVPM 1681 Query: 1313 PSSEGA----SPEPPP----PDALAAPYVLYPGFQP--VPVTALMP 1348 S + A S PP P A Y++YPGF P +P AL P Sbjct: 1682 TSQQQAVAPMSISVPPLALSPGAYGPTYMIYPGFLPTVLPTNALQP 1727 Score = 42.7 bits (99), Expect = 0.002 Identities = 125/579 (21%), Positives = 203/579 (35%), Gaps = 108/579 (18%) Query: 6 KKCTDAFSDSSSIGSVLDDADREVSSLTDRAFRSLCISEDTSFHDSYLAVSPDITRQVFG 65 K+ D S +SS S LDDAD+EV +LT RAFRSL + + S S ++ FG Sbjct: 633 KELVDYSSGASSAVSELDDADKEVRNLTSRAFRSLAYPYFEALNISSRESSTTLSEVGFG 692 Query: 66 TFHQ------RTVGHTQRKSGIWSQLPSQGT---EHSGWAATFQQLPKYVQGEEKYPKTS 116 + VG +S + S S + SG AT QL Y+Q ++ K Sbjct: 693 RWSTFLDLKCGGVGARVEQSLLRSSAASVAAGLRKGSGARATADQL--YIQSKKSQTKA- 749 Query: 117 PPPTPVQRRLEVPVSGLRSSNKPV-------------SKVSTLIKSFDRTESQRCESRPT 163 LE VS + K V S+V TL++ + + S P Sbjct: 750 ---------LEFVVSKVEGEIKHVETPLCFQKQVQTGSRVVTLLEPLNVRSESKASSAPG 800 Query: 164 ASKPPALKNPPKFAPLPENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQESSK 223 + A K P K SA+ + S T + S R G Q+S Sbjct: 801 PGR--ATKGPGKGP-----------GSAYTD------DGSETSEGSKPTSRADGPQKSKF 841 Query: 224 NPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRG-KGTFLHSENSAFESWNA 282 + + S + ++ + HH T + G +G+ E + Sbjct: 842 ASSLLKNVISKKMQREHEFKMERGEVMDTSHHLSGTSKETEGARGSERQRERGLQRQSSR 901 Query: 283 H-----QPKLLERKDTA--GTVPESKAPKHYGDTTLLREPCP----PERTVSPCQVQASC 331 H + ++ D G+V SK+P T R P + C+++ S Sbjct: 902 HSEAGSEYTVVSMSDAGGEGSVAGSKSPVFKASTPRERNAGPGRNFTDGHTEVCEIKKSA 961 Query: 332 SQEENRLAAGALSTSI-PWGCRDPGAQVFAVEGKAPSSQPDSQEKPAQPPWRKPKTGKKG 390 S+ + + +++ W + +++++ Q P K K K G Sbjct: 962 SETVKGIFLRSQNSAFRSW------------------KEKEAEKREEQAPIGKLKLPKGG 1003 Query: 391 --KESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLP---------VEPN----- 434 + L + K R + P+++ A P + P Sbjct: 1004 DWRADLGEISASKNTIMSRLFVPNIQQTPKDKQPRKQATKYPAAQATSTAVIRPKAPEIK 1063 Query: 435 ------EHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQS 488 + FNI+KLLTP + A + + + + G ++ Q Sbjct: 1064 IRLGSVQQPSSDFNIAKLLTPKLAGGSA-SNLFKTIEDNSRAQQKLFRGDNLEKVPHFQV 1122 Query: 489 RD-SYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEK 526 RD KSKA L ++DVRK +K + SS V E+ Sbjct: 1123 RDIRDKSKAQGPLHQVRDVRKLIKGSGDSSDKGSVTPEQ 1161 >gi|113416182 PREDICTED: hypothetical protein LOC285556 [Homo sapiens] Length = 1826 Score = 71.2 bits (173), Expect = 7e-12 Identities = 92/346 (26%), Positives = 139/346 (40%), Gaps = 64/346 (18%) Query: 1043 PPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQA---PGGPELLPEEPNQASPW 1099 PP + V + P P P + + +AS+I + A P GP PE P+ A Sbjct: 1406 PPVHKDVERTQPLQPLPPLPSNRNVFTVSASSIQKTGGVAGKFPQGPS--PESPSAAKGI 1463 Query: 1100 ASS-------SPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAG 1152 S SPA +++T+ + GS+ LE S D + L + + Sbjct: 1464 KSQGLRSLKISPATRAPPDEVTNR---KSGSN--LEKSNSDCE------NYLTIPLKGSS 1512 Query: 1153 TSGRLELPAQLERTASKPPAV---PPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKP 1209 +G L S+P A PP + A + S R + + + S +P Sbjct: 1513 AAGEL---------LSRPGASREGPPNSSAATLCSLPPLSARSQVPSSSKGSQVSGTSRP 1563 Query: 1210 C----PEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVH-----RHSVSGFSEPVGRRPGG 1260 P++ +T P P+ P H + PP + V FS P P Sbjct: 1564 AWRTKPDNPRETVAAPPGPQS-PEHPPTTIYHQPPLPFTLQGAQPQVLCFSPPSMPAPA- 1621 Query: 1261 PQSLTPLPAYPATQ--------KVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSI 1312 P + P+P P Q K+L D +G+Y++ D P+Q + +DPETG+YV V + Sbjct: 1622 PAASAPVPTDPFQQAQPQQTQRKMLLDVTTGQYYLVDTPVQPMTRRLFDPETGQYVDVPM 1681 Query: 1313 PSSEGA----SPEPPP----PDALAAPYVLYPGFQP--VPVTALMP 1348 S + A S PP P A Y++YPGF P +P AL P Sbjct: 1682 TSQQQAVAPMSISVPPLALSPGAYGPTYMIYPGFLPTVLPTNALQP 1727 Score = 42.7 bits (99), Expect = 0.002 Identities = 125/579 (21%), Positives = 203/579 (35%), Gaps = 108/579 (18%) Query: 6 KKCTDAFSDSSSIGSVLDDADREVSSLTDRAFRSLCISEDTSFHDSYLAVSPDITRQVFG 65 K+ D S +SS S LDDAD+EV +LT RAFRSL + + S S ++ FG Sbjct: 633 KELVDYSSGASSAVSELDDADKEVRNLTSRAFRSLAYPYFEALNISSRESSTTLSEVGFG 692 Query: 66 TFHQ------RTVGHTQRKSGIWSQLPSQGT---EHSGWAATFQQLPKYVQGEEKYPKTS 116 + VG +S + S S + SG AT QL Y+Q ++ K Sbjct: 693 RWSTFLDLKCGGVGARVEQSLLRSSAASVAAGLRKGSGARATADQL--YIQSKKSQTKA- 749 Query: 117 PPPTPVQRRLEVPVSGLRSSNKPV-------------SKVSTLIKSFDRTESQRCESRPT 163 LE VS + K V S+V TL++ + + S P Sbjct: 750 ---------LEFVVSKVEGEIKHVETPLCFQKQVQTGSRVVTLLEPLNVRSESKASSAPG 800 Query: 164 ASKPPALKNPPKFAPLPENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQESSK 223 + A K P K SA+ + S T + S R G Q+S Sbjct: 801 PGR--ATKGPGKGP-----------GSAYTD------DGSETSEGSKPTSRADGPQKSKF 841 Query: 224 NPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRG-KGTFLHSENSAFESWNA 282 + + S + ++ + HH T + G +G+ E + Sbjct: 842 ASSLLKNVISKKMQREHEFKMERGEVMDTSHHLSGTSKETEGARGSERQRERGLQRQSSR 901 Query: 283 H-----QPKLLERKDTA--GTVPESKAPKHYGDTTLLREPCP----PERTVSPCQVQASC 331 H + ++ D G+V SK+P T R P + C+++ S Sbjct: 902 HSEAGSEYTVVSMSDAGGEGSVAGSKSPVFKASTPRERNAGPGRNFTDGHTEVCEIKKSA 961 Query: 332 SQEENRLAAGALSTSI-PWGCRDPGAQVFAVEGKAPSSQPDSQEKPAQPPWRKPKTGKKG 390 S+ + + +++ W + +++++ Q P K K K G Sbjct: 962 SETVKGIFLRSQNSAFRSW------------------KEKEAEKREEQAPIGKLKLPKGG 1003 Query: 391 --KESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLP---------VEPN----- 434 + L + K R + P+++ A P + P Sbjct: 1004 DWRADLGEISASKNTIMSRLFVPNIQQTPKDKQPRKQATKYPAAQATSTAVIRPKAPEIK 1063 Query: 435 ------EHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQS 488 + FNI+KLLTP + A + + + + G ++ Q Sbjct: 1064 IRLGSVQQPSSDFNIAKLLTPKLAGGSA-SNLFKTIEDNSRAQQKLFRGDNLEKVPHFQV 1122 Query: 489 RD-SYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEK 526 RD KSKA L ++DVRK +K + SS V E+ Sbjct: 1123 RDIRDKSKAQGPLHQVRDVRKLIKGSGDSSDKGSVTPEQ 1161 >gi|113415686 PREDICTED: hypothetical protein LOC285556 [Homo sapiens] Length = 1826 Score = 71.2 bits (173), Expect = 7e-12 Identities = 92/346 (26%), Positives = 139/346 (40%), Gaps = 64/346 (18%) Query: 1043 PPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQA---PGGPELLPEEPNQASPW 1099 PP + V + P P P + + +AS+I + A P GP PE P+ A Sbjct: 1406 PPVHKDVERTQPLQPLPPLPSNRNVFTVSASSIQKTGGVAGKFPQGPS--PESPSAAKGI 1463 Query: 1100 ASS-------SPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAG 1152 S SPA +++T+ + GS+ LE S D + L + + Sbjct: 1464 KSQGLRSLKISPATRAPPDEVTNR---KSGSN--LEKSNSDCE------NYLTIPLKGSS 1512 Query: 1153 TSGRLELPAQLERTASKPPAV---PPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKP 1209 +G L S+P A PP + A + S R + + + S +P Sbjct: 1513 AAGEL---------LSRPGASREGPPNSSAATLCSLPPLSARSQVPSSSKGSQVSGTSRP 1563 Query: 1210 C----PEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVH-----RHSVSGFSEPVGRRPGG 1260 P++ +T P P+ P H + PP + V FS P P Sbjct: 1564 AWRTKPDNPRETVAAPPGPQS-PEHPPTTIYHQPPLPFTLQGAQPQVLCFSPPSMPAPA- 1621 Query: 1261 PQSLTPLPAYPATQ--------KVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSI 1312 P + P+P P Q K+L D +G+Y++ D P+Q + +DPETG+YV V + Sbjct: 1622 PAASAPVPTDPFQQAQPQQTQRKMLLDVTTGQYYLVDTPVQPMTRRLFDPETGQYVDVPM 1681 Query: 1313 PSSEGA----SPEPPP----PDALAAPYVLYPGFQP--VPVTALMP 1348 S + A S PP P A Y++YPGF P +P AL P Sbjct: 1682 TSQQQAVAPMSISVPPLALSPGAYGPTYMIYPGFLPTVLPTNALQP 1727 Score = 42.7 bits (99), Expect = 0.002 Identities = 125/579 (21%), Positives = 203/579 (35%), Gaps = 108/579 (18%) Query: 6 KKCTDAFSDSSSIGSVLDDADREVSSLTDRAFRSLCISEDTSFHDSYLAVSPDITRQVFG 65 K+ D S +SS S LDDAD+EV +LT RAFRSL + + S S ++ FG Sbjct: 633 KELVDYSSGASSAVSELDDADKEVRNLTSRAFRSLAYPYFEALNISSRESSTTLSEVGFG 692 Query: 66 TFHQ------RTVGHTQRKSGIWSQLPSQGT---EHSGWAATFQQLPKYVQGEEKYPKTS 116 + VG +S + S S + SG AT QL Y+Q ++ K Sbjct: 693 RWSTFLDLKCGGVGARVEQSLLRSSAASVAAGLRKGSGARATADQL--YIQSKKSQTKA- 749 Query: 117 PPPTPVQRRLEVPVSGLRSSNKPV-------------SKVSTLIKSFDRTESQRCESRPT 163 LE VS + K V S+V TL++ + + S P Sbjct: 750 ---------LEFVVSKVEGEIKHVETPLCFQKQVQTGSRVVTLLEPLNVRSESKASSAPG 800 Query: 164 ASKPPALKNPPKFAPLPENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQESSK 223 + A K P K SA+ + S T + S R G Q+S Sbjct: 801 PGR--ATKGPGKGP-----------GSAYTD------DGSETSEGSKPTSRADGPQKSKF 841 Query: 224 NPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRG-KGTFLHSENSAFESWNA 282 + + S + ++ + HH T + G +G+ E + Sbjct: 842 ASSLLKNVISKKMQREHEFKMERGEVMDTSHHLSGTSKETEGARGSERQRERGLQRQSSR 901 Query: 283 H-----QPKLLERKDTA--GTVPESKAPKHYGDTTLLREPCP----PERTVSPCQVQASC 331 H + ++ D G+V SK+P T R P + C+++ S Sbjct: 902 HSEAGSEYTVVSMSDAGGEGSVAGSKSPVFKASTPRERNAGPGRNFTDGHTEVCEIKKSA 961 Query: 332 SQEENRLAAGALSTSI-PWGCRDPGAQVFAVEGKAPSSQPDSQEKPAQPPWRKPKTGKKG 390 S+ + + +++ W + +++++ Q P K K K G Sbjct: 962 SETVKGIFLRSQNSAFRSW------------------KEKEAEKREEQAPIGKLKLPKGG 1003 Query: 391 --KESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLP---------VEPN----- 434 + L + K R + P+++ A P + P Sbjct: 1004 DWRADLGEISASKNTIMSRLFVPNIQQTPKDKQPRKQATKYPAAQATSTAVIRPKAPEIK 1063 Query: 435 ------EHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQS 488 + FNI+KLLTP + A + + + + G ++ Q Sbjct: 1064 IRLGSVQQPSSDFNIAKLLTPKLAGGSA-SNLFKTIEDNSRAQQKLFRGDNLEKVPHFQV 1122 Query: 489 RD-SYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEK 526 RD KSKA L ++DVRK +K + SS V E+ Sbjct: 1123 RDIRDKSKAQGPLHQVRDVRKLIKGSGDSSDKGSVTPEQ 1161 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 56.2 bits (134), Expect = 2e-07 Identities = 112/508 (22%), Positives = 190/508 (37%), Gaps = 67/508 (13%) Query: 212 PGRKHGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGE---PGRGKGT 268 P K E+E +K+P + PA + + E+K P PV E P K Sbjct: 562 PEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSP 621 Query: 269 FLHSENSAFESWNAHQPKLLERKDTAGTVPESKAPKHYGDTTLLREPCPPERTVSPCQVQ 328 S E + + K K+ A + ++K+P+ E PE+ SP + + Sbjct: 622 VKEEAKSPAEVKSPEKAK-SPTKEEAKSPEKAKSPEK-------EEAKSPEKAKSPVKAE 673 Query: 329 ASCSQEENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPSSQPDSQEKPAQPPWRKPKTGK 388 A S E+ + A + S P + P + E K+P EK P + K+ + Sbjct: 674 AK-SPEKAKSPVKAEAKS-PEKAKSPVKE----EAKSP-------EKAKSPVKEEAKSPE 720 Query: 389 KGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISKLLT 448 K K +++ E KT + P +P++ S A L V+ E P Sbjct: 721 KAKSPVKE--EAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTP--------- 769 Query: 449 PIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLK-DVR 507 + A AD P E+ SP + + K P + +S +KAP K +V+ Sbjct: 770 ---AKEEARSPADKFP-EKAKSPVKE----EVKSPEKAKSPLKEDAKAPEKEIPKKEEVK 821 Query: 508 KRVKSTYS------SSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESPPNELSKERP 561 VK P K +EK +++ S P P E KE Sbjct: 822 SPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPA 881 Query: 562 ADDPTASHINPQKDPTADPSE-PSADSYLTLSTAPTIAKAPFYVNGEAAERSSYENKEVE 620 + P S + +K+ D + P+ + AP AK + + E++ KE + Sbjct: 882 VEKPKESKVEAKKEEAEDKKKVPTPE-----KEAP--AKVEVKEDAKPKEKTEVAKKEPD 934 Query: 621 GELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPGGATEKMKTHQLENGLSRSVSQE- 679 P+ + + +E P K + + PE EK KT +++S+E Sbjct: 935 DAKAKEPSKPA---EKKEAAPEKKDTKEEKAKKPE-----EKPKTEAKAKEDDKTLSKEP 986 Query: 680 TEPEREAGLQNTHLNQKFFPGPLSPEEE 707 ++P+ E +++ +QK P E+ Sbjct: 987 SKPKAEKAEKSSSTDQKDSKPPEKATED 1014 Score = 35.4 bits (80), Expect = 0.40 Identities = 62/327 (18%), Positives = 125/327 (38%), Gaps = 44/327 (13%) Query: 371 DSQEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLP 430 + +EK A+ K + G G+E + EE+T++ PP +P+++ +++ + Sbjct: 472 EEEEKEAKEEEGKEEEG--GEEEEAEGGEEETKS----PPAEEAASPEKE-AKSPVKEEA 524 Query: 431 VEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRD 490 P E P +K + + + A S E SPP + +E+ S + + Sbjct: 525 KSPAEAKSPEKEEAKSPAEV----KSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKS 580 Query: 491 SYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEE 550 K+K+P+ K+ K S + E+ + + K PV E Sbjct: 581 PEKAKSPA-----KEEAKSPAEAKSPEKAKSPVKEEAKSPAEAK-SPVKE--------EA 626 Query: 551 SPPNELSKERPADDPTASHI-------NPQKDPTADPSEPSADSYLTLSTAPTIAKAPFY 603 P E+ A PT +P+K+ P E + + +P AK+P Sbjct: 627 KSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSP-EKAKSPVKAEAKSPEKAKSPVK 685 Query: 604 VNGEAAERSSYENKE-----------VEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNR 652 ++ E++ KE V+ E + S + + + ++ + Sbjct: 686 AEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAK 745 Query: 653 DPEPGGATEKMKTHQLENGLSRSVSQE 679 PE + EK KT +++ +++ ++E Sbjct: 746 SPEKAKSPEKAKTLDVKSPEAKTPAKE 772 Score = 31.6 bits (70), Expect = 5.7 Identities = 87/482 (18%), Positives = 163/482 (33%), Gaps = 50/482 (10%) Query: 761 SAGDSQKDEKENVMRKDELQYCALSNGHACLENRSQGEALQRERESV-------SGGRTR 813 S +++ EKE E++ + A E +S EA E+E S + + Sbjct: 526 SPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAK 585 Query: 814 KASAEEANFRGSWIGENKGTTFSQAKDLTPSPSSASNRHMLFTIKDNTLRATPVIKP--I 871 + EEA K S K+ SP+ A + +K+ V P Sbjct: 586 SPAKEEAKSPAEAKSPEKAK--SPVKEEAKSPAEAKS-----PVKEEAKSPAEVKSPEKA 638 Query: 872 MLPLLRTMSLEDSLSSGHKEEELPRPEWGEDPGFCAPENQDILGTSTPTNTRGT-RVKCM 930 P + S KEE PE + P ++ + + + + K Sbjct: 639 KSPTKEEAKSPEKAKSPEKEEA-KSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSP 697 Query: 931 ANEVMEDPGQGSSMARMEASQPAPKGNFPSMPLVGEGDRVKAPPDAAPGLVASNCKSGSA 990 E + P + S + EA P K P ++ K+P K + Sbjct: 698 VKEEAKSPEKAKSPVKEEAKSPE-KAKSPVKEEAKTPEKAKSP-----------VKEEAK 745 Query: 991 DSGKLAAPWHIPTIAL--PEGDIEDQPPPWQPENCWEEQTPG-FKSHFLSTPRAGPPGRR 1047 K +P T+ + PE + P + + E+ K S +A P + Sbjct: 746 SPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLK- 804 Query: 1048 LVPSERANSPNPGSPGESSACSPAASNIWEESSQAPGGPELLPEEPNQASPWASSSPARV 1107 E A +P P + SP + + P+ EE A+P + + Sbjct: 805 ----EDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATP--KTEEKKD 858 Query: 1108 TRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELPAQLERTA 1167 +++E+ + P +E E P+ S ++ A ++ P + Sbjct: 859 SKKEEAPK----KEAPKPKVEEKKEPA-VEKPKESKVEAKKEEAEDKKKVPTPEK----- 908 Query: 1168 SKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRER 1227 P V K + + ++A K +A+E +++ + PE + +++ P E+ Sbjct: 909 EAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEK 968 Query: 1228 PR 1229 P+ Sbjct: 969 PK 970 >gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax homolog 2 [Homo sapiens] Length = 1210 Score = 54.7 bits (130), Expect = 6e-07 Identities = 131/560 (23%), Positives = 204/560 (36%), Gaps = 84/560 (15%) Query: 123 QRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTESQRCESRPTASKPPALKNPPKFAP--LP 180 Q + + S SN S L ++S+ +S T KPP+ PP AP LP Sbjct: 400 QNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPS-APQSLP 458 Query: 181 ENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQESSKNPEMACHGSSSFLPAAN 240 E + SA +E ++ +S + +S +N + P N Sbjct: 459 EPVASAHSSSA-------ESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTN 511 Query: 241 ----DTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENSAFESWNAHQPKLLERKDTAGT 296 D S+ +P P + EP R S +SA ++ + + Sbjct: 512 KWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAP 571 Query: 297 VPESKAPKHYGDTTLLREPC---PPER-TVSPCQ----VQASCSQEENRLAAGALSTS-I 347 +AP H G + + P PP+R TV Q V+AS G + Sbjct: 572 RAPPEAP-HPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLL 630 Query: 348 PWGCRDPGAQ---VFAVEGKAPSSQPDSQEKPAQPPWRKPKTGK----------KGKESL 394 P+G RD ++ +G+ P + ++ KPA PP + K K G E Sbjct: 631 PYGSRDQTSKDKPKVKTKGR-PRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPA 689 Query: 395 QDTLEEKTQ--------TNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDP---PFNI 443 +D +E++T T +GPP H+ + + V+ + D P Sbjct: 690 KDNVEDRTPEHFALVPLTESQGPP----HSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRD 745 Query: 444 SKLLTPI---IPSKHALDSADSQPAERTPSPPG---QLNGYQEKEP-------SECQSRD 490 +KLL+P+ P + + R P PPG + ++K+P SE +S D Sbjct: 746 TKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSD 805 Query: 491 S-------YKSKAPSLLFNLK-DVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGV 542 S K +A N K + K +KS SSS KT+ Q S Sbjct: 806 SSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQS--SKKE 863 Query: 543 ILPNGLEESPPNELSKERPADDPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAKAPF 602 +LP PP S ++PA P + D SA S + +I K Sbjct: 864 MLP-----PPPVSSSSQKPA-KPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQR- 916 Query: 603 YVNGEAAERSSYENKEVEGE 622 V G+ + RSS E+K G+ Sbjct: 917 RVEGKGS-RSSSEHKGSSGD 935 Score = 38.9 bits (89), Expect = 0.036 Identities = 110/535 (20%), Positives = 188/535 (35%), Gaps = 104/535 (19%) Query: 113 PKTSPPPTPVQ-RRLEVPVSGLRSSNKPVSKV----STLIKSFDRTESQRCESRPTASKP 167 P SP V+ E P L + +P S+ S KS + RP + Sbjct: 242 PAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQD 301 Query: 168 PALKNPPKFAPLPENSVNFCFD--------SAFLTVRRVPAE-VSNTHQNSYQPGRKHGE 218 A P+ PLPE+ F+ A LT ++P++ V T+ N H Sbjct: 302 QAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEV-----HCV 356 Query: 219 QESSKNPEMACHGSSSFLPAANDTATLCESKFPSP----HHKPVTGEPGRGKGTFLHSEN 274 +E K EM H L A + +T SKFP P H + + T + + Sbjct: 357 EEILK--EMT-HSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHS 413 Query: 275 SAFESWNAHQPKLLERKDTAGTVPESKAPKHYGDTTLLREPCPPERTVSPCQVQASCSQE 334 ++ + ++ L+ D+ + E K + P P+ P A S Sbjct: 414 NSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSA---PPSAPQSLPEPV-ASAHSSSA 469 Query: 335 ENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPSSQPDSQE-KPAQPPWRKPKTGKKGKES 393 E+ + + S+S + ++ SS DS+E +P + P +P+ K Sbjct: 470 ESESTSDSDSSS---------------DSESESSSSDSEENEPLETPAPEPEPPTTNKWQ 514 Query: 394 LQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISKLLTPIIPS 453 L + L + +Q P P+ EP + S Sbjct: 515 LDNWLTKVSQ------PAAPPEGPRS-----------TEPPRRHP-------------ES 544 Query: 454 KHALDSADSQPAERTPSPPGQLNGYQEKEPSE--------CQSRDSYKSKAPSLLFNLKD 505 K + DSA SQ + PP + + + P E CQ + + K Sbjct: 545 KGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQ 604 Query: 506 VRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESPPNELSKERPADDP 565 +K VK++ + +R + G++EP +LP G + + K + P Sbjct: 605 PKKPVKASARAG---------SRTSLQGEREP----GLLPYGSRDQTSKDKPKVKTKGRP 651 Query: 566 TASHINPQKDPTADPSEPSADSYLTLSTAPTIAKAPFYVNGEAAERSSYENKEVE 620 A+ N K PS++ S+ P +KA ++G + + E++ E Sbjct: 652 RAAASNEPKPAV----PPSSEKKKHKSSLPAPSKA---LSGPEPAKDNVEDRTPE 699 Score = 31.6 bits (70), Expect = 5.7 Identities = 54/261 (20%), Positives = 94/261 (36%), Gaps = 23/261 (8%) Query: 1043 PPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPGGPELLPEEPNQASPWASS 1102 PP PS + P P + SS+ +++ + SS + E N+ + Sbjct: 444 PPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAP 503 Query: 1103 SPARVTRRE---DLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLEL 1159 P T + D V + + P S E R D ATS + + Sbjct: 504 EPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPP 563 Query: 1160 PAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKPCP-------- 1211 P +++SK P PP+ +R+ + + +++ Q Q G Q KP Sbjct: 564 P----KSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTV-GTKQPKKPVKASARAGSR 618 Query: 1212 EDLEQTQQRPLCP---RERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLP 1268 L+ ++ L P R++ + P V++ P + +EP P + Sbjct: 619 TSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRP----RAAASNEPKPAVPPSSEKKKHKS 674 Query: 1269 AYPATQKVLQDPQSGEYFVFD 1289 + PA K L P+ + V D Sbjct: 675 SLPAPSKALSGPEPAKDNVED 695 >gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] Length = 904 Score = 53.9 bits (128), Expect = 1e-06 Identities = 96/399 (24%), Positives = 150/399 (37%), Gaps = 55/399 (13%) Query: 1038 TPRAGPPGRRLVPS---ERANSPNPGSPGESSACSPAASNIWEESSQAPGGPELLPEEPN 1094 +PR P RR+ P R+ SP S++ S ++S+ S++P P++P Sbjct: 322 SPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSP------PKKP- 374 Query: 1095 QASPWASSSPARVTRREDLT-------HALVWEGGSDPLLELSAEDLRTLSPRGSLLDVA 1147 P +SSP R TRR + H P S ++ R S + V Sbjct: 375 ---PKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSV- 430 Query: 1148 TSPAGTSGRLELPAQLERTASKPPAVPPK----TEKALRRAKKLAS----KRRKTDQAQE 1199 SP TSG++ E+ S PA P+ +E + K+A+ ++R+ + Q Sbjct: 431 -SPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQN 489 Query: 1200 KHGESQEGKPCPEDLEQTQQRPLCPRE--RPRHNFPVVRSLPPPVHRHSVSGFSEPVGRR 1257 + S G + E+ ++ + E R R + P + P P R + P GRR Sbjct: 490 QQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKE---TSPRGRR 546 Query: 1258 PGGP------QSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQ--VKIKTFYDPETGKYVK 1309 P + +P PA P ++ P P + + + P +Y Sbjct: 547 RRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSP 606 Query: 1310 VSIPSSEGASPEPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASA 1369 P ASP PPPP A+P P P + Q S+P R+ P S+ Sbjct: 607 SPPPKRRTASP-PPPPKRRASP-------SPPPKRRVSHSPPPKQRSSPVTKRRSPSLSS 658 Query: 1370 ARARTQSVHESGLQL-DPGPHGDCTPHSAGQRPHGPPQS 1407 + S S + P P+ HS RP P S Sbjct: 659 KHRKGSSPSRSTREARSPQPN---KRHSPSPRPRAPQTS 694 Score = 44.3 bits (103), Expect = 9e-04 Identities = 159/721 (22%), Positives = 231/721 (32%), Gaps = 149/721 (20%) Query: 742 DQQKMWFTENQREDRRKDVSAGDSQKDEKENVMRKDELQYCALSNGHACLENRSQGEALQ 801 +Q+K+ + Q ED+ K K+EKE+ K E R + ++ Sbjct: 137 EQEKLASMKKQDEDKDK------RDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVR 190 Query: 802 RERESVSGGRTRKASAEEANFRGSWIGENKGTTFSQAKDLTPSPSSASNRHMLFTIKDNT 861 RER+ R + + + + K+ TP S + ++++ T Sbjct: 191 RERKRSHSRSPRHRTKSRSP-----------SPAPEKKEKTPELPEPSVKVKEPSVQEAT 239 Query: 862 LRAT--PVIKPIMLPLLRTMSLEDSLSSGHKEEELPRPEWGEDPGFCAPENQDILGTSTP 919 + V KP +P + S E + S KE+E RP +++ + +P Sbjct: 240 STSDILKVPKPEPIPEPKEPSPEKN-SKKEKEKEKTRPR-----SRSRSKSRSRTRSRSP 293 Query: 920 TNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAPKGNFPS--MPLVGEGDRVKAPPDAA 977 ++TR R + + P + S R +P+P+ P MP R ++P Sbjct: 294 SHTRPRR-RHRSRSRSYSPRRRPSPRR----RPSPRRRTPPRRMPPPPRHRRSRSPVRRR 348 Query: 978 PGLVASNCKSGSADSGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFKSHFLS 1037 AS S S+ S + PP +P +P K+ LS Sbjct: 349 RRSSASLSGSSSSSSSS-----------------RSRSPPKKPPK--RTSSPPRKTRRLS 389 Query: 1038 TPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEES--SQAPGGPELLPEEPNQ 1095 P A PP RR PS A P P + +P SN +S S +PG + Sbjct: 390 -PSASPPRRRHRPSPPATPP----PKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKG 444 Query: 1096 ASPWASSSPARVTRREDLTHALVWEGG----------------------SDPLLELSAED 1133 S SPA R+ +L+ + +GG SD S+ED Sbjct: 445 TEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSED 504 Query: 1134 ---------------------LRTLSPRGSLLDVATSPAGTSGRLELPAQLERTASKPPA 1172 R+ SP TSP G R P R S PA Sbjct: 505 ERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPA 564 Query: 1173 VPPK-----TEKALRRAKKLASKRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRER 1227 PP+ T RR +RR + + P P +T P P+ R Sbjct: 565 PPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRR 624 Query: 1228 PRHNFPVVRSL---PPPVHRHSV--------------SGFS------EPVGRRPGGPQSL 1264 + P R + PPP R S G S E +P S Sbjct: 625 ASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSP 684 Query: 1265 TPLPAYPATQK--------VLQDPQSGEY---------FVFDLPLQVKIKTFYDPETGKY 1307 +P P P T PQ + V P KIK P Sbjct: 685 SPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSV 744 Query: 1308 VKVSIPSSEGASPEPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRA 1367 +VS S SPEP A P P P T P + +PT PR Sbjct: 745 RRVSSSRSVSGSPEPAAKKPPAPP---SPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRN 801 Query: 1368 S 1368 S Sbjct: 802 S 802 Score = 43.1 bits (100), Expect = 0.002 Identities = 115/519 (22%), Positives = 175/519 (33%), Gaps = 96/519 (18%) Query: 113 PKTSPPP-------TPVQRRLE--VPVSGLRSSNKPVSKVSTLIKSFDRTESQRCESR-- 161 P+ PPP +PV+RR +SG SS+ S K RT S ++R Sbjct: 329 PRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRL 388 Query: 162 -PTASKP-------PALKNPPK--FAPLPENSVNFCFDSAFLTVRRVPAEVSN----THQ 207 P+AS P P PPK +P P+ S ++ R +V+ + Sbjct: 389 SPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKR 448 Query: 208 NSYQPGRKH-----GEQESSKNPEMACHGS--------SSFLPAANDTATLCESKFPSPH 254 S P K E E K +MA S +++D+ + S+ P Sbjct: 449 ESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPK 508 Query: 255 HKPV-TGEPGRGKGTFLHSENSAFESWNAHQPKLLERKDTAGTVPESKAPKHYGDTTLLR 313 V GE GR + +S S + K + G S +P T R Sbjct: 509 RSHVKNGEVGRRR------RHSPSRSASPSPRKRQKETSPRGRRRRSPSPP---PTRRRR 559 Query: 314 EPCPP-----ERTVSPCQVQASCSQEENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPSS 368 P P RT +P + + S R + S P R + +P Sbjct: 560 SPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPP 619 Query: 369 QPDSQEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALD 428 P + P+ PP R+ K+ T +R P L +KH S + Sbjct: 620 PPKRRASPSPPPKRRVSHSPPPKQ------RSSPVTKRRSPSLSSKHRKGSSPSRSTREA 673 Query: 429 LPVEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAER---TPSPPGQLNGYQEKEPSE 485 +PN+ + P P A ++ S P R + SP + Q PS Sbjct: 674 RSPQPNKRHSPS-----------PRPRAPQTSSSPPPVRRGASSSPQRR----QSPSPST 718 Query: 486 CQSRDSYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILP 545 R ++ P K++K S SP V + V G EP + Sbjct: 719 RPIRRVSRTPEP----------KKIKKAASPSP-QSVRRVSSSRSVSGSPEPAAK----- 762 Query: 546 NGLEESPPNELSKERPADD-PTASHINPQKDPTADPSEP 583 +PP+ + + P+ + A + K PT PS P Sbjct: 763 --KPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPP 799 Score = 42.7 bits (99), Expect = 0.002 Identities = 74/315 (23%), Positives = 113/315 (35%), Gaps = 66/315 (20%) Query: 116 SPPPTPVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTESQRCESRP-----TASKPPAL 170 SP P P +RR P R+ + P + S + + +R P TAS PP Sbjct: 562 SPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPP 621 Query: 171 KNPPKFAPLPENSVNFC----FDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQES----- 221 K +P P+ V+ S+ +T RR P+ +S+ H+ P R E S Sbjct: 622 KRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPS-LSSKHRKGSSPSRSTREARSPQPNK 680 Query: 222 --SKNPEMACHGSSSFLPAANDTATLCESK--FPSPHHKPV-----TGEPGRGKGTFLHS 272 S +P +SS P A+ + PSP +P+ T EP + K S Sbjct: 681 RHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPS 740 Query: 273 ENSAFESWNAHQPKLLERKDTAGTVPESKAPKHYGDTTLLREPCPPERTVSPCQVQASCS 332 P+ + R ++ +V S P + P PP SP Q Q Sbjct: 741 ------------PQSVRRVSSSRSVSGSPEP------AAKKPPAPP----SPVQSQ---- 774 Query: 333 QEENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPSSQPDSQEKPAQPPWRKPKTGKKGKE 392 S S W P + K+P+ P Q K K KK K+ Sbjct: 775 -----------SPSTNWSPAVP-----VKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKK 818 Query: 393 SLQDTLEEKTQTNQR 407 +D +K + +++ Sbjct: 819 HKKDKKHKKHKKHKK 833 Score = 34.3 bits (77), Expect = 0.89 Identities = 49/218 (22%), Positives = 88/218 (40%), Gaps = 29/218 (13%) Query: 1007 PEGDIEDQPPPWQPEN-CWEEQTPGFKSHFL---STPRAGPPGRRLVPSERAN-SPNPGS 1061 P+ + PPP Q + + ++P S S R+ R P++R + SP P + Sbjct: 631 PKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRA 690 Query: 1062 PGESSACSP----AASNIWEESSQAPGGPELL----PEEPNQASPWASSSPARVTRREDL 1113 P SS+ P A+S+ S +P + EP + AS SP V R + Sbjct: 691 PQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR---V 747 Query: 1114 THALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELPAQLERTASKPPAV 1173 + + G +P + P V + T+ +P + ++ + P+ Sbjct: 748 SSSRSVSGSPEPAAK---------KPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPS- 797 Query: 1174 PPKT---EKALRRAKKLASKRRKTDQAQEKHGESQEGK 1208 PP+ E ++ KK K+ K D+ +KH + ++ K Sbjct: 798 PPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEK 835 Score = 31.2 bits (69), Expect = 7.5 Identities = 88/429 (20%), Positives = 155/429 (36%), Gaps = 67/429 (15%) Query: 368 SQPDSQEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNAL 427 S + +E+ P RK ++ + S E+ +++ R P TK E Sbjct: 161 SSREKRERSRSPRRRKSRSPSPRRRS-SPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEK 219 Query: 428 --DLPVEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSE 485 +LP + +P + + I+ + + P + PSP +EKE + Sbjct: 220 TPELPEPSVKVKEPSVQEATSTSDILK----VPKPEPIPEPKEPSPEKNSKKEKEKEKTR 275 Query: 486 CQSRDSYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILP 545 +SR KS++ R R +S + P + + P P Sbjct: 276 PRSRSRSKSRS----------RTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRR----P 321 Query: 546 NGLEESPPNELSKERPADDPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAKAPFYVN 605 + +PP + P + S + ++ +A S S+ S + S +P K P Sbjct: 322 SPRRRTPPRRMPPP-PRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSP--PKKP---- 374 Query: 606 GEAAERSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPGGATEKMKT 665 +R+S ++ + P+ S P R HRP + P T T Sbjct: 375 ---PKRTSSPPRKTR---RLSPSAS---PPRRRHRP---------SPPATPPPKTRHSPT 416 Query: 666 HQLENGLSRSVSQETEPEREAGLQNTH--LNQKFFPGPLSPEEEDVFYSDSQSD------ 717 Q N +R P R +G H ++ P P +P+ V S+S+ D Sbjct: 417 PQQSN-RTRKSRVSVSPGRTSGKVTKHKGTEKRESPSP-APKPRKVELSESEEDKGGKMA 474 Query: 718 FMPSLKGKAKF------STSSSDQSFASFDDQQKMWFTENQREDRRKDVSAGDS-----Q 766 S++ + ++ S+S S S +S D++ K +N RR+ S S + Sbjct: 475 AADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPR 534 Query: 767 KDEKENVMR 775 K +KE R Sbjct: 535 KRQKETSPR 543 >gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e [Homo sapiens] Length = 1451 Score = 53.1 bits (126), Expect = 2e-06 Identities = 111/490 (22%), Positives = 166/490 (33%), Gaps = 80/490 (16%) Query: 884 SLSSGHKEEELPRPEWGEDPGFCAPENQDILGTSTPTNTR-----GTRVKCMANEVMEDP 938 S S +EEE E + A N +LG P++ + T M P Sbjct: 83 STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP 142 Query: 939 GQGSSMARMEASQPAPKGNFPS--MPLVGEGDRVKAPP----DAAPGLV-ASNCKSGSAD 991 G ++A + + + K PS LV E + + P A PG+V A S S D Sbjct: 143 ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSED 202 Query: 992 SGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFKSHFLS------TPR----A 1041 + + + EG +P + + +++P K+ TP+ A Sbjct: 203 TSSSSDETDV------EGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGA 256 Query: 1042 GPPGRRL-VPSERANSPNPGSPGESSACSPAASNI-------WEESSQAPG----GPELL 1089 PP +R P E + S GS E A + S + ++ AP G Sbjct: 257 LPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGAT 316 Query: 1090 PEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATS 1149 P P +A AS + A + E S+ E S + T + + L A+ Sbjct: 317 PAPPGKAGAVASQTKAGKPEEDS-------ESSSE---ESSDSEEETPAAKALLQAKASG 366 Query: 1150 PAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKP 1209 G PA+ PA P KT A+ AK A KR + Q+ + +S+E P Sbjct: 367 KTSQVGAASAPAKESPRKGAAPAPPGKTGPAV--AKAQAGKREEDSQSSSEESDSEEEAP 424 Query: 1210 CPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPA 1269 + +P P VR+ P S G P P+ P A Sbjct: 425 A--------------QAKPSGKAPQVRAASAPAKE------SPRKGAAPAPPRKTGPAAA 464 Query: 1270 YPATQKVLQDPQ-SGEYFVFDLPLQVKIKTFYDPETGKYVKVSI-------PSSEGASPE 1321 K +D + S E D + GK +V P +GA P Sbjct: 465 QVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPV 524 Query: 1322 PPPPDALAAP 1331 PP A P Sbjct: 525 PPGKVGPATP 534 >gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d [Homo sapiens] Length = 1488 Score = 53.1 bits (126), Expect = 2e-06 Identities = 111/490 (22%), Positives = 166/490 (33%), Gaps = 80/490 (16%) Query: 884 SLSSGHKEEELPRPEWGEDPGFCAPENQDILGTSTPTNTR-----GTRVKCMANEVMEDP 938 S S +EEE E + A N +LG P++ + T M P Sbjct: 83 STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP 142 Query: 939 GQGSSMARMEASQPAPKGNFPS--MPLVGEGDRVKAPP----DAAPGLV-ASNCKSGSAD 991 G ++A + + + K PS LV E + + P A PG+V A S S D Sbjct: 143 ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSED 202 Query: 992 SGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFKSHFLS------TPR----A 1041 + + + EG +P + + +++P K+ TP+ A Sbjct: 203 TSSSSDETDV------EGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGA 256 Query: 1042 GPPGRRL-VPSERANSPNPGSPGESSACSPAASNI-------WEESSQAPG----GPELL 1089 PP +R P E + S GS E A + S + ++ AP G Sbjct: 257 LPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGAT 316 Query: 1090 PEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATS 1149 P P +A AS + A + E S+ E S + T + + L A+ Sbjct: 317 PAPPGKAGAVASQTKAGKPEEDS-------ESSSE---ESSDSEEETPAAKALLQAKASG 366 Query: 1150 PAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKP 1209 G PA+ PA P KT A+ AK A KR + Q+ + +S+E P Sbjct: 367 KTSQVGAASAPAKESPRKGAAPAPPGKTGPAV--AKAQAGKREEDSQSSSEESDSEEEAP 424 Query: 1210 CPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPA 1269 + +P P VR+ P S G P P+ P A Sbjct: 425 A--------------QAKPSGKAPQVRAASAPAKE------SPRKGAAPAPPRKTGPAAA 464 Query: 1270 YPATQKVLQDPQ-SGEYFVFDLPLQVKIKTFYDPETGKYVKVSI-------PSSEGASPE 1321 K +D + S E D + GK +V P +GA P Sbjct: 465 QVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPV 524 Query: 1322 PPPPDALAAP 1331 PP A P Sbjct: 525 PPGKVGPATP 534 >gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo sapiens] Length = 1450 Score = 53.1 bits (126), Expect = 2e-06 Identities = 111/490 (22%), Positives = 166/490 (33%), Gaps = 80/490 (16%) Query: 884 SLSSGHKEEELPRPEWGEDPGFCAPENQDILGTSTPTNTR-----GTRVKCMANEVMEDP 938 S S +EEE E + A N +LG P++ + T M P Sbjct: 83 STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP 142 Query: 939 GQGSSMARMEASQPAPKGNFPS--MPLVGEGDRVKAPP----DAAPGLV-ASNCKSGSAD 991 G ++A + + + K PS LV E + + P A PG+V A S S D Sbjct: 143 ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSED 202 Query: 992 SGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFKSHFLS------TPR----A 1041 + + + EG +P + + +++P K+ TP+ A Sbjct: 203 TSSSSDETDV------EGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGA 256 Query: 1042 GPPGRRL-VPSERANSPNPGSPGESSACSPAASNI-------WEESSQAPG----GPELL 1089 PP +R P E + S GS E A + S + ++ AP G Sbjct: 257 LPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGAT 316 Query: 1090 PEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATS 1149 P P +A AS + A + E S+ E S + T + + L A+ Sbjct: 317 PAPPGKAGAVASQTKAGKPEEDS-------ESSSE---ESSDSEEETPAAKALLQAKASG 366 Query: 1150 PAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKP 1209 G PA+ PA P KT A+ AK A KR + Q+ + +S+E P Sbjct: 367 KTSQVGAASAPAKESPRKGAAPAPPGKTGPAV--AKAQAGKREEDSQSSSEESDSEEEAP 424 Query: 1210 CPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPA 1269 + +P P VR+ P S G P P+ P A Sbjct: 425 A--------------QAKPSGKAPQVRAASAPAKE------SPRKGAAPAPPRKTGPAAA 464 Query: 1270 YPATQKVLQDPQ-SGEYFVFDLPLQVKIKTFYDPETGKYVKVSI-------PSSEGASPE 1321 K +D + S E D + GK +V P +GA P Sbjct: 465 QVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPV 524 Query: 1322 PPPPDALAAP 1331 PP A P Sbjct: 525 PPGKVGPATP 534 >gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c [Homo sapiens] Length = 958 Score = 53.1 bits (126), Expect = 2e-06 Identities = 111/490 (22%), Positives = 166/490 (33%), Gaps = 80/490 (16%) Query: 884 SLSSGHKEEELPRPEWGEDPGFCAPENQDILGTSTPTNTR-----GTRVKCMANEVMEDP 938 S S +EEE E + A N +LG P++ + T M P Sbjct: 83 STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP 142 Query: 939 GQGSSMARMEASQPAPKGNFPS--MPLVGEGDRVKAPP----DAAPGLV-ASNCKSGSAD 991 G ++A + + + K PS LV E + + P A PG+V A S S D Sbjct: 143 ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSED 202 Query: 992 SGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFKSHFLS------TPR----A 1041 + + + EG +P + + +++P K+ TP+ A Sbjct: 203 TSSSSDETDV------EGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGA 256 Query: 1042 GPPGRRL-VPSERANSPNPGSPGESSACSPAASNI-------WEESSQAPG----GPELL 1089 PP +R P E + S GS E A + S + ++ AP G Sbjct: 257 LPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGAT 316 Query: 1090 PEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATS 1149 P P +A AS + A + E S+ E S + T + + L A+ Sbjct: 317 PAPPGKAGAVASQTKAGKPEEDS-------ESSSE---ESSDSEEETPAAKALLQAKASG 366 Query: 1150 PAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKP 1209 G PA+ PA P KT A+ AK A KR + Q+ + +S+E P Sbjct: 367 KTSQVGAASAPAKESPRKGAAPAPPGKTGPAV--AKAQAGKREEDSQSSSEESDSEEEAP 424 Query: 1210 CPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPA 1269 + +P P VR+ P S G P P+ P A Sbjct: 425 A--------------QAKPSGKAPQVRAASAPAKE------SPRKGAAPAPPRKTGPAAA 464 Query: 1270 YPATQKVLQDPQ-SGEYFVFDLPLQVKIKTFYDPETGKYVKVSI-------PSSEGASPE 1321 K +D + S E D + GK +V P +GA P Sbjct: 465 QVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPV 524 Query: 1322 PPPPDALAAP 1331 PP A P Sbjct: 525 PPGKVGPATP 534 >gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo sapiens] Length = 1393 Score = 52.8 bits (125), Expect = 2e-06 Identities = 247/1249 (19%), Positives = 404/1249 (32%), Gaps = 238/1249 (19%) Query: 137 NKPVSKVSTLIKSFDRTESQRCESRPTASKPPALKNPPKFAPLPENSVNFCFDSAFLTVR 196 +KP K + K+ D S P S+ ENS N D R Sbjct: 93 SKPTDKPTGNSKTIDHKSSTDNHEAPPTSE--------------ENSSNQGKDPMIRNQR 138 Query: 197 RV-PAEVSNTHQNSYQPGRKH--GEQESSKNPEMACHGSSSFLPAANDTATLCES----- 248 V PA+ + TH+ S G+KH +S N + G S+ ++ T E Sbjct: 139 SVDPADSTTTHKES--AGKKHITPAPKSKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTL 196 Query: 249 -KFPSPHHKPVTGEPGRGKGTFLHSENSAFESWNAHQPKLLERKDTAGTVPESKAPKHYG 307 K + HK T G S E A + T GT PE Sbjct: 197 DKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYK---TTGT-PEESEKTEDS 252 Query: 308 DTTLLREPCPPERTVSPCQVQASCSQEENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPS 367 TT+ + + T + ++A L+ S+ G A E PS Sbjct: 253 RTTVASDKLLTKTT----------KNIQETISANELTQSLAEPTEHGGRT--ANENNTPS 300 Query: 368 SQPDSQEKPAQPPWRKPKTGKKGK--------ESLQDTLEEKTQTNQRGPPLYTKHNPQE 419 PA+P + +T + E+ + T E T GP N + Sbjct: 301 --------PAEPTENRERTANENTTLSPAEPIENRERTANENTAPFPAGPT----ENREM 348 Query: 420 QFSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKH----ALDSADSQPAE--------- 466 +EN L P EP EH + N + +P P++H A ++ PAE Sbjct: 349 TANENTTL-FPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTP 407 Query: 467 ----RTPSPPGQLNGYQEK-------------EPSECQSRDSYKSKAPSLLFNLKDVRKR 509 +T S + + E+ EP+E + R + ++ PS ++ Sbjct: 408 FANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETT 467 Query: 510 VKSTYSSSPLLKVLDEKTRGK---VDGKQEPVSNGVILPNGLEESP-------------- 552 + SP+ + +T EP NG P E++ Sbjct: 468 ANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTP 527 Query: 553 -PNELSKERPADDPTASHINPQKDPTADPSEPSADSYLT----LSTAPTIAKAPFYVNGE 607 NE + PA+ + T P+EP+ + T T P++A+ E Sbjct: 528 LANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPT-----E 582 Query: 608 AAERSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPGGATEKMKTHQ 667 +R+ + N++ +S + EH R L+ N P P TE + Sbjct: 583 NGQRTPFANEKT----------TSSSAEPTEHEERTPLANE--NTTPSPAEPTENRE--- 627 Query: 668 LENGLSRSVSQETEPEREAGLQNTHL--NQK--FFPG-PLSPEEEDVFYSDSQSDFMPSL 722 R+ ++ T P +N + N+K FP P E + S P+ Sbjct: 628 ------RTANENTTPSPAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTE 681 Query: 723 KGK----AKFSTSSSDQSFASFDDQQKMWFTENQREDRRKDVSAGDSQKDEKENVMRKDE 778 G+ A T+SS ++ + EN + + +EK + Sbjct: 682 NGQRTPFANEKTTSSSAEPTEHGERTPL-ANENTTLSPAEPTENRERTANEKTTPFPAEP 740 Query: 779 LQYCALSNGHACLENRSQGEALQRERESVSGGRTRKASAEEANFRGSWIGENKGTTFSQA 838 + + EN + A E +G RT A+ + K T F+ Sbjct: 741 TE----NRERTANENTTPSPAQPTE----NGDRTPLANEKTTPSLAEPTENGKRTPFANE 792 Query: 839 KDLTPSPSSASNRHMLFTIKDNTLRA----------TPVIKPIMLPLLRTMSLEDSLSSG 888 K + S + +NT + T K P T + E + + Sbjct: 793 KTTSSSAEPTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTAN-- 850 Query: 889 HKEEELPRP-EWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVM----EDPGQGSS 943 E+ P P E E+ + A EN + S T + +ANE +P + Sbjct: 851 --EKTTPFPAEPTENREWTANENTTL---SPAEPTEHEEMTPLANEKTTLSPAEPTENGE 905 Query: 944 MARMEASQPAPKGNFPSMPLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIPT 1003 + P P+ G+R + A + G + + A P Sbjct: 906 RTPFTNEKTTPSSAEPT----EHGERTPLANEITTPSRAEPTEHGERIANEKATPSPAKP 961 Query: 1004 IALPEGDIEDQPPPWQPENCWE-EQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSP 1062 E + + P E E+TP + ++P +E+ +P+P P Sbjct: 962 TEHGETTVNEDTTPSSAEPTENGERTPLANENTTTSPTESTEHGERTANEK-TTPSPAEP 1020 Query: 1063 GESSACSPAASNIWEESSQAPGGPELLPEEPNQASPWASSSPARVTRREDLTH------A 1116 E +P+A+ E++ +P P E A+ + SP + T + T Sbjct: 1021 TEHGERTPSAN---EKTIPSPAKPTEHEEMTPSANENTTPSPVKPTEHGEKTTLANEKIT 1077 Query: 1117 LVWEGGSD--------------PLLELSAEDLRTLSPRGSLLDVATSPA-----GTSGRL 1157 L EG ++ L + + RT SP + A TS + Sbjct: 1078 LSPEGPTEHGAKTTSANEKITPSLAKPTEHGERTTSPNDKITSSAAESTEHRDRATSANV 1137 Query: 1158 ELPAQLE------RTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEK---HGES---Q 1205 PA E RT + TEK+ +K S KT + EK + E Sbjct: 1138 ITPAPAEPIKHAKRTTLAHEKMTQVTEKSTEHPEKTTSTTEKTTRTPEKPTLYSEKTICT 1197 Query: 1206 EGK--PCPED----------LEQTQQRPLCPRERPRHNFPVVRSLPPPV 1242 +GK P PE +T + P+ E P V +++ P V Sbjct: 1198 KGKNTPVPEKPTENLGNTTLTTETIKAPVKSTENPEKTAAVTKTIKPSV 1246 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 51.2 bits (121), Expect = 7e-06 Identities = 135/591 (22%), Positives = 198/591 (33%), Gaps = 88/591 (14%) Query: 810 GRTRKASAEEANFRGSWIGENKGTTFSQAKDLTPSPSSASNRHMLFTIKDNTLRATPVIK 869 G TR A N +G AK+ +P P S+ R T R P+ + Sbjct: 78 GPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGR------ASGTTRPGPLGQ 131 Query: 870 PIMLPLLRTMSLEDSLSSGHKEEELPRPEWGEDPGFCAPENQDILGTS--TPTNTRGTRV 927 + +S E++++ G K E P+ A +D G + TP+ R Sbjct: 132 KGL-----RISAEETVARG-KATEAPKRS-----ALSAGARRDTSGPTPGTPSPAMARRS 180 Query: 928 KCMANEV----------MEDPGQG-----SSMARMEASQPAPKGNFPSMPLVGEGDRVKA 972 + EV P +G SS + ++P+P P G G + A Sbjct: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAAR--RRPSAGGGLQRPA 238 Query: 973 PPDAAPGL--VASNCKSGSADSGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPG 1030 + ++S +SG + G AP H P+ P+G +PP P ++ P Sbjct: 239 SRSLSSSATPLSSPARSGPSARGTPRAPAH-PSQPKPKGLQALRPPQVTPPR--KDAAPA 295 Query: 1031 FKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNI--WEESSQAPGGPEL 1088 S+P A P + S+ A P +P SS A+ + S AP + Sbjct: 296 L-GPLSSSPLATPSPSAALQSQ-APPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQT 353 Query: 1089 LPEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVAT 1148 LP P A+P + ++ + + TH+ + P L +AT Sbjct: 354 LPSPP--ATPPSQATTSLGSPTLQATHSFL--------------------PSPPLSPLAT 391 Query: 1149 SPAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGK 1208 P L LP + PPA PP + LA+ + A H Sbjct: 392 PPPQAPPALALPPL--QAPPSPPASPPLSP--------LATPSPQAPNALAVHLLQAPFS 441 Query: 1209 PCPEDLEQTQ-----QRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQS 1263 P P Q P+ P P P + PP S S P+ P Sbjct: 442 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA-SPPMSPSATPPPQ 500 Query: 1264 LTPLPAYPATQKVLQDPQSGEYFVFDLPLQV--KIKTFYDPETGKYVKVSIPSSEGASPE 1321 P A P Q PQ+ PLQ + + S+P S A+P Sbjct: 501 APPPLAAPPLQLAKPPPQAPPALATP-PLQALPSPPASFPGQAPFSPSASLPMSPLATPP 559 Query: 1322 PPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASAARA 1372 P P LAAP + P P T P R P GPR + A A Sbjct: 560 PQAPPVLAAPLLQVPPSPPASPTLQAPRR--PPTPGPDTSVSGPRLTLALA 608 >gi|239740773 PREDICTED: similar to diffuse panbronchiolitis critical region 1 [Homo sapiens] Length = 1400 Score = 50.4 bits (119), Expect = 1e-05 Identities = 128/593 (21%), Positives = 202/593 (34%), Gaps = 126/593 (21%) Query: 137 NKPVSKVSTLIKSFDRTESQRCESRPTASKPPALKNPPKFAPLPENSVNFCFDSAFLTVR 196 +KP K + K+ D S P S+ ENS N D R Sbjct: 155 SKPTDKPTGNSKTIDHKSSTDNHEAPPTSE--------------ENSSNQGKDPMIRNQR 200 Query: 197 RV-PAEVSNTHQNSYQPGRKH--GEQESSKNPEMACHGSSSFLPAANDTATLCES----- 248 V PA+ + TH+ S G+KH +S N + G S+ ++ T E Sbjct: 201 SVDPADSTTTHKES--AGKKHITPAPKSKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTL 258 Query: 249 -KFPSPHHKPVTGEPGRGKGTFLHSENSAFESWNAHQPKLLERKDTAGTVPESKAPKHY- 306 K + HK T G S E A + T GT ES+ + Sbjct: 259 DKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYK---TTGTPEESEKTEDSR 315 Query: 307 ----GDTTLLREPCPPERTVSPCQVQASCSQEENRLAAGALSTSIPWGCRDPGAQVFAVE 362 D L + + T+S ++ S ++ A + P + E Sbjct: 316 TTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRTANENNTP-------SPAEPTE 368 Query: 363 GKAPSSQPDSQEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQFS 422 + ++ ++ PA+P E+ + T E T GP N + + Sbjct: 369 NRERTANENTTLSPAEPT-----------ENRERTANENTAPFPAGPT----ENREMTAN 413 Query: 423 ENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKE 482 EN L P EP EH + N + +P P++H +A+ TPSP E Sbjct: 414 ENTTL-FPAEPTEHGERTANENTTPSPAEPTEHGERTANE---NTTPSP---------AE 460 Query: 483 PSECQSRDSYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGV 542 P+E R + + K+T SS+ E T G++ P++N Sbjct: 461 PTEHGERTPFAND---------------KTTSSSA-------ESTE---HGERTPLANEN 495 Query: 543 ILPNGLE-----ESPPNELSKERPADDPTASHINPQKDPTADPSEPSADSYLTLSTAPTI 597 P+ E E NE + PA + T P EP+ + T + T Sbjct: 496 TTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTP 555 Query: 598 AKAPFYVNGEAAERSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPG 657 + A NG +R+ + N++ +S + EH R L+ N P P Sbjct: 556 SPAEPTENG---QRTPFANEKT----------TSSSAEPTEHGERTPLANE--NTTPSPA 600 Query: 658 GATEKMKTHQLENGLSRSVSQETEPE----REAGLQNTHLNQKFFPGPLSPEE 706 TE + R+ +++T P E G + N+K P P E Sbjct: 601 EPTENRE---------RTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTE 644 Score = 45.1 bits (105), Expect = 5e-04 Identities = 94/437 (21%), Positives = 147/437 (33%), Gaps = 54/437 (12%) Query: 196 RRVPAEVSNTHQNSYQPGRKHGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHH 255 +R P T +S +P +HGE+ N S P N T E PSP Sbjct: 565 QRTPFANEKTTSSSAEP-TEHGERTPLANENTT---PSPAEPTENRERTANEKTTPSPAE 620 Query: 256 KPVTGE--PGRGKGTFLHSENSAFESWNAHQPKLLERKDTAG----TVPESKAPKHYGDT 309 G+ P + T + + A + N + K T+ T E + P +T Sbjct: 621 PTENGDRTPLANEKT---TPSLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENT 677 Query: 310 TLLREPCPP----ERTVSPCQVQASCSQEENR-LAAGALSTSIPWGCRDPGAQVFAVEGK 364 T P P ERT + + ENR + A +T P + K Sbjct: 678 T--PSPAEPTENRERTANENTTPSPAGPTENREMTANEKTTLFP--AEPTENRERTANEK 733 Query: 365 APSSQPDSQEKPAQPPWRKPKTGKKGKESLQD-----TLEEKTQTNQRGPPLYTKHNPQE 419 SS + E + P+ KT E + E T + GP +E Sbjct: 734 TTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAGPT-----ENRE 788 Query: 420 QFSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHA----LDSADSQPAERTPSPPGQL 475 + + P EP E+ + N + +P P+++ L + + P+ P+ G+ Sbjct: 789 RTANEKTTPFPAEPTENRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENGKR 848 Query: 476 NGY-QEKEPSECQSRDSYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGK 534 + EK S + + P N +SSP E T + Sbjct: 849 TPFANEKTTSSSAEPTEHAERTPLANENT-----------TSSPA-----EPTENRERTA 892 Query: 535 QEPVSNGVILPNGLEESPPNELSKERPADDPTASHINPQKDPTADPSEPSADSYLTLSTA 594 E + P ES NE + PA+ ++ T P+EP+ +T Sbjct: 893 NEKTTQFPAEPTENRESTANEKTTPFPAEPTENREWTANENTTLSPAEPTEHEEMTPLMV 952 Query: 595 PTIAKAPFYVNGEAAER 611 +APF G AER Sbjct: 953 DENLQAPFR-QGSCAER 968 >gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] Length = 2752 Score = 50.4 bits (119), Expect = 1e-05 Identities = 247/1175 (21%), Positives = 399/1175 (33%), Gaps = 201/1175 (17%) Query: 219 QESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENSAFE 278 ++ SK P H SSS P + SP + P R S FE Sbjct: 824 KQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQR---------RSCFE 874 Query: 279 SWNAHQPKLLERKDTAGTVPESKAPKHYGDTTLLREPCPPERTVSPCQVQASCSQEENRL 338 S + P+L R + + S P+ T + P R+ SP + R Sbjct: 875 S--SPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSP---SRSSSPQPKVKAIISPRQRS 929 Query: 339 AAGALSTSIPW--------------GCRDPGAQVFAVEGKAPSSQPDSQEKPAQPPWRKP 384 +G+ S S C + +++ + SS PD++ KP PP R+ Sbjct: 930 HSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPP-RQS 988 Query: 385 KTGKKGKESLQDTLEEKTQTNQRGPPLYTKHN--PQEQFSENNALDLP------------ 430 +G S+ + K QT GP L + PQE+ ++ P Sbjct: 989 HSG-----SISPYPKVKAQT-PPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSS 1042 Query: 431 VEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPS-ECQSR 489 P E Y F +S L + + P R+ + ++ + PS + +S+ Sbjct: 1043 TPPGESY---FGVSSL--------QLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQ 1091 Query: 490 DSYK-----SKAPSLLFNLKDVRKRVKSTYSSSPLLK--VLDEKTRGKVDGKQEPV--SN 540 S K S +P + ++ + +S+SP+LK + E++R + D P SN Sbjct: 1092 TSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSN 1151 Query: 541 GVILPNGLEESPPNELSKERPADDPTASHINPQKD-----PTADPSEPSADSYLTLSTAP 595 ++ + LE + E P +D TAS QKD P D E S TL T P Sbjct: 1152 SLLGQSRLETAESKEKMALPPQEDATASPPR-QKDKFSPFPVQDRPESSLVFKDTLRTPP 1210 Query: 596 T----IAKAPFYVNGEAAERSSYENKEVEGELEMG--PAG--------------SSWCPD 635 +P +A +S +++E+ +E PAG +S Sbjct: 1211 RERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFES 1270 Query: 636 SREHRPRKHLSLRLCNRDPEPGGATEKMKTHQLENGLSRSVSQETEPEREAGLQNTHLNQ 695 S E R +SL L + + ++ ++ + S PE + L N+ L + Sbjct: 1271 SPEVEERPAVSLTL-----DQSQSQASLEAVEVPSMASSWGGPHFSPEHKE-LSNSPLRE 1324 Query: 696 KFF--------PGPLSPEEEDVFYSDSQSDFM----------PSLKGKAKFSTSSS-DQS 736 F GPL E F S+ + D PSL K + + SS S Sbjct: 1325 NSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSS 1384 Query: 737 FASFDDQQKMWFTENQR----------EDRRKDVSAGDSQKDEKENVMRKDELQYCALSN 786 S D +K + NQ ++ S+ S + K+ + R + + S Sbjct: 1385 ELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRR--SRSG 1442 Query: 787 GHACLENRSQGEALQRERESVSGGRTRKASAEEANFRGSWIGENKGTTFSQAKDLTPSPS 846 L + S + R S+SG RG E + +A TP P Sbjct: 1443 SSPGLRDGSGTPS----RHSLSGSSPGMKDIPRTPSRGR--SECDSSPEPKALPQTPRPR 1496 Query: 847 SAS------NRHMLFTIKDNTLRATPVIKPIMLPLLRTMSLEDSLSSGHKEEELPRPEWG 900 S S N L ++ + + V + + RT + S S +E ++ Sbjct: 1497 SRSPSSPELNNKCLTPQRERSGSESSVDQK---TVARTPLGQRSRSGSSQELDVKPSASP 1553 Query: 901 EDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAPKGNFPS 960 ++ T TP R + ++ ++ + S S P K + Sbjct: 1554 QERSESDSSPDSKAKTRTPLRQRS---RSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRA 1610 Query: 961 MPLVGEG-DRVKAPPDAAPGLVASNCKSGSADSGK----------LAAPWHIP------- 1002 P G D P AP + +SGS+ G+ ++P H P Sbjct: 1611 APRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARR 1670 Query: 1003 -TIALPEGDIEDQPPPWQ------PENCWEEQTPGFKSHFLSTPRA---GPPGRRLVPSE 1052 + + PE + + PP + PE + + S+P PP R PS Sbjct: 1671 GSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPS- 1729 Query: 1053 RANSPNPGSPGESSACSPAASNIWEESSQAPG-GPELLPEEPNQASPWASSSPARVTRRE 1111 +SP P SS +AS+ +++ G P P ++ + R TRR Sbjct: 1730 -VSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRR 1788 Query: 1112 DLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELPAQLERTASK-- 1169 D GS + R+ R + +G R + RT+S+ Sbjct: 1789 D-------RSGSSQSTSRRRQRSRS---RSRVTRRRRGGSGYHSRSPARQESSRTSSRRR 1838 Query: 1170 --PPAVPPKTEKALR-RAKKLASKRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRE 1226 PP + K R R KR ++ + H S+ P + R Sbjct: 1839 RGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRR 1898 Query: 1227 RPRHNFPVV----RSLPPPVHRHSVSGFSEPVGRR 1257 R R V RS PV R + PV RR Sbjct: 1899 RSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRR 1933 Score = 45.1 bits (105), Expect = 5e-04 Identities = 82/353 (23%), Positives = 126/353 (35%), Gaps = 50/353 (14%) Query: 1040 RAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPGGPELLPEEPNQASPW 1099 R+ P RR S R+ S P G S + +PA + A P + Sbjct: 636 RSRSPARR---SGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRS 692 Query: 1100 ASSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLEL 1159 S +P R R + +LV G S RT RG +G+S + Sbjct: 693 RSRTPRRGRSR---SRSLVRRGRSHS---------RTPQRRGR--------SGSSSERKN 732 Query: 1160 PAQLERTASKPPAVPP--KTEKALRRAKKLASKRRKTDQAQEKHGESQEGKPCPEDLEQT 1217 ++ + S+ + P K+ + RR++ L+S R K PCP+ QT Sbjct: 733 KSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQT 792 Query: 1218 QQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGP-----QSLTPLP---- 1268 R R R + P +S PP R S S S P ++ P S +P P Sbjct: 793 PPR----RSRSGSSQPKAKSRTPP--RRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKS 846 Query: 1269 AYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPSSEGASPEPPPPDAL 1328 P Q + PQ+ E V + ++ ++ +K PS S PP Sbjct: 847 GTPPRQGSITSPQANEQSV-----TPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKS 901 Query: 1329 AAPYVLYPGFQPVPVTALMPL-----RCSSQLSAPTFLRQGPRASAARARTQS 1376 + P P P + + R S S+P+ R R + R+R+ S Sbjct: 902 STPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVS 954 Score = 34.7 bits (78), Expect = 0.68 Identities = 56/245 (22%), Positives = 84/245 (34%), Gaps = 45/245 (18%) Query: 1177 TEKALRRAKKLASKRRKTD----QAQEKHGESQEGKPCPEDLEQTQQRPLCPRERPRHNF 1232 T K+ R++K KR ++ +++ H + D +++ R + H Sbjct: 233 TPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKT---HTT 289 Query: 1233 PVVRSLPPPVHRHSVSG---FSEP---VGRRPGGPQSLTPLPAYPATQKVLQDPQSGEYF 1286 + P P G FSEP +RP P++ T P+ P K Sbjct: 290 ALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDK----------- 338 Query: 1287 VFDLPLQVKIKTFYDPETGKYVKVSIPSSEGASPEPPPPDALAAPYVLYPGF-QPVPVTA 1345 D + K T P P PEPP P L A + G QP+ T Sbjct: 339 --DKDKKEKSATRPSPS---------PERSSTGPEPPAPTPLLAE--RHGGSPQPLATTP 385 Query: 1346 LM--PLRCSSQLSAPTFLRQGPRASAARARTQSVHESGLQLDPGPHGDCTPHSAGQRPHG 1403 L P+ S+ S PT R P++ ++ S S P P A P Sbjct: 386 LSQEPVNPPSEAS-PTRDRSPPKSPEKLPQSSSSESS----PPSPQPTKVSRHASSSPES 440 Query: 1404 PPQSP 1408 P +P Sbjct: 441 PKPAP 445 Score = 34.3 bits (77), Expect = 0.89 Identities = 191/1020 (18%), Positives = 331/1020 (32%), Gaps = 140/1020 (13%) Query: 313 REPCPPER-TVSPCQVQASCSQEEN---RLAAGALSTSIPWGCRDPGAQVFAVEGKAPSS 368 +E P +R V+ A ++++N R A G + + DP Q A E K P+ Sbjct: 108 KEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDP--QRRAREAKQPAP 165 Query: 369 QPDS------QEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQ-EQF 421 +P + ++ P K K KK K+ + + + ++ KH + E Sbjct: 166 EPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESK 225 Query: 422 SENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHA-----LDSADSQP------------ 464 + P + D S+ TP S+ A DSA S Sbjct: 226 KRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAK 285 Query: 465 ------AERTPSPPGQLNGYQEKEPSECQSRDSYK-------SKAPSLLFNLKDVRKRVK 511 A R+PSP G + SE + + + +K PS + KD K+ K Sbjct: 286 THTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEK 345 Query: 512 STYSSSPLLK-------------VLDEKTRGKVDG------KQEPVSNGVILPNGLEESP 552 S SP + +L E+ G QEPV+ + SP Sbjct: 346 SATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSP 405 Query: 553 PNELSK---------ERPADDPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAKAPFY 603 P K P+ PT + P + P+ S+ +S++PT Sbjct: 406 PKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRS-- 463 Query: 604 VNGEAAERSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPGGATEKM 663 +G A S+ + ++ SR P K R +R P+ + Sbjct: 464 -HGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSR--SRSPQWRRSRSAQ 520 Query: 664 KTHQLENGLSRSVSQETEPEREAGLQNTHLNQKFFPGPLSPEEEDVFYSDSQS------D 717 + + + R S+ P+R ++ + ++ G +S S + Sbjct: 521 RWGRSRSPQRRGRSR--SPQRPGWSRSRNTQRR---GRSRSARRGRSHSRSPATRGRSRS 575 Query: 718 FMPSLKGKAKFSTSSSDQSFASFDDQQKMWFTENQREDRRKDVSAGDSQKDEKENVMRKD 777 P+ +G+++ T + +S + +++ R R + + + + V R+ Sbjct: 576 RTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRS 635 Query: 778 ELQYCALSNGHA-----CLENRSQGEALQRERESVS-----------------GGRTRKA 815 + A +G + RS+ R S S GR+R Sbjct: 636 RSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSR 695 Query: 816 SAEEANFRGSWIGENKGTTFSQAKDLTPSPSSASNRHMLFTIKDNTLR--ATPVIKPIML 873 + R + +G + S+ S+S R R ++P +K + Sbjct: 696 TPRRGRSRSRSL-VRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRI 754 Query: 874 PLLRTMSLEDSLSSGHKEEELPRPEWGEDPGFC------APENQDILGTSTP---TNTRG 924 R+ SL S L R G P C P + G+S P + T Sbjct: 755 SSRRSRSLSSPRSKAKSRLSLRRSLSGSSP--CPKQKSQTPPRRSRSGSSQPKAKSRTPP 812 Query: 925 TRVKCMANEVMEDPGQGSSMARMEASQPAPKGNFPSMPLVGEGDRVKAPPDAAPGLVASN 984 R + ++ + + S +S P PK + P G +A + S Sbjct: 813 RRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSC 872 Query: 985 CKSGSADSGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPP 1044 +S K P ++ PP Q + P K+ R+ Sbjct: 873 FESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSG 932 Query: 1045 GRRLVPSERANSPNPGSPGESSACSPAASNI---WEESSQAPGGPELLPEEPNQASPWAS 1101 PS + P S CS S + + S + ++ PE P + S S Sbjct: 933 SSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGS 992 Query: 1102 SSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVA----TSPAGTS--- 1154 SP + + + G P + ++D S GSL A ++P G S Sbjct: 993 ISPYPKVKAQTPPGPSL-SGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFG 1051 Query: 1155 -GRLELPAQLERTAS-KPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKPCPE 1212 L+L Q + + + P+ ++ + L SK Q K G S+ P E Sbjct: 1052 VSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSK----SQTSPKGGRSRSSSPVTE 1107 Score = 34.3 bits (77), Expect = 0.89 Identities = 65/313 (20%), Positives = 109/313 (34%), Gaps = 47/313 (15%) Query: 946 RMEASQPAPKGN----FPSMPLVGEGDRVKAPPDAAPGLVASNCKSGSADS------GKL 995 R ++ PAPK S D ++ +A + +G + S G+ Sbjct: 247 RSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEG 306 Query: 996 AAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERAN 1055 AP+ P + + QP + +E++ K + P P P A Sbjct: 307 DAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAP 366 Query: 1056 SP-----NPGSPGESSACSPAASNIWEESSQA--------PGGPELLPEEPNQASPWASS 1102 +P + GSP + A +P + S+A P PE LP+ + S S Sbjct: 367 TPLLAERHGGSP-QPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSP 425 Query: 1103 SPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELPAQ 1162 P +V+R HA S E + GS ++++SP + R A+ Sbjct: 426 QPTKVSR-----HA-----------SSSPESPKPAPAPGSHREISSSPT-SKNRSHGRAK 468 Query: 1163 LERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKPCPEDLEQTQQ--R 1220 +++ S P+ R+ A + R + K G S+ P Q+ R Sbjct: 469 RDKSHSHTPS----RRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGR 524 Query: 1221 PLCPRERPRHNFP 1233 P+ R R P Sbjct: 525 SRSPQRRGRSRSP 537 Score = 30.8 bits (68), Expect = 9.8 Identities = 44/217 (20%), Positives = 70/217 (32%), Gaps = 37/217 (17%) Query: 894 LPRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPA 953 +P + GE P + L P R + SS + +S + Sbjct: 2501 VPHSDVGEPPASTGAQQPSALAALQPAKERRSS---------SSSSSSSSSSSSSSSSSS 2551 Query: 954 PKGNFPSMPLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIPTIALPEGDIED 1013 + S EG + P+ A V S PT A E E Sbjct: 2552 SSSSSGSSSSDSEGSSLPVQPEVALKRVPS------------------PTPAPKEAVREG 2593 Query: 1014 QPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAAS 1073 +PP E TP + S+ + S ++S + S SS+ S ++S Sbjct: 2594 RPP---------EPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2644 Query: 1074 NIWEESSQAPGGPELLPEEPNQASPWASSSPARVTRR 1110 + S PG P+ LP+ + P +R R+ Sbjct: 2645 SSSSPSPAKPG-PQALPKPASPKKPPPGERRSRSPRK 2680 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 46.6 bits (109), Expect = 2e-04 Identities = 116/493 (23%), Positives = 152/493 (30%), Gaps = 48/493 (9%) Query: 919 PTNTRGTRVKCMANEVMEDPGQGSSMARMEAS-QPAPKGN----FPSMPLVGEGDRVKAP 973 P + RG R N PG SS R + +P P G + V G +AP Sbjct: 86 PASGRGERAPPAKNT---SPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAP 142 Query: 974 PDAAPGLVASNCKSGSADSGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFKS 1033 +A A SG A A E + P +P E S Sbjct: 143 KRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSS 202 Query: 1034 HFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPGGPELLPEEP 1093 + P R PS P S SS+ +P +S S + G P P Sbjct: 203 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA--RSGPSARGTPRAPAHP 260 Query: 1094 NQASPWASSS--PARVTR-REDLTHAL--------VWEGGSDPLLELSAEDLRTL-SPRG 1141 +Q P + P +VT R+D AL S P + L+TL SP Sbjct: 261 SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPA 320 Query: 1142 SLLDVATSPAGT---------------SGRLELPAQLERTASKPPAVPPKTEKALRRAKK 1186 + AT+ G+ S P Q + PP P + A Sbjct: 321 TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSP 380 Query: 1187 LASKRRKTDQAQEKHGESQEGKPCPEDLEQTQ-----QRPLCPRERPRHNFPVVRSLPPP 1241 LA+ + A H P P Q P+ P P P + PP Sbjct: 381 LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL 440 Query: 1242 VHRHSVSGFSEPVGRRPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQV--KIKTF 1299 S S P+ P P A P Q PQ+ PLQ Sbjct: 441 QVPPSPPA-SPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP-PLQALPSPPAS 498 Query: 1300 YDPETGKYVKVSIPSSEGASPEPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPT 1359 + + S+P S A+P P P LAAP + P P T P R P Sbjct: 499 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR--PPTPGPD 556 Query: 1360 FLRQGPRASAARA 1372 GPR + A A Sbjct: 557 TSVSGPRLTLALA 569 >gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] Length = 1682 Score = 46.2 bits (108), Expect = 2e-04 Identities = 96/360 (26%), Positives = 120/360 (33%), Gaps = 75/360 (20%) Query: 1041 AGPPGRRLVPSERANSPNPGSPG-ESSACSPAA----SNIWEESSQ-------------- 1081 A PPG RLVP+ P P PG ES C PA S++ E Q Sbjct: 322 AHPPGHRLVPAAPPG-PGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAATT 380 Query: 1082 --APGGPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGGSD----PLLELSAEDLR 1135 P P P P + +SSS + R + + G+D P LE+S Sbjct: 381 ACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGI--PGADHYQTPALEVSHHGRL 438 Query: 1136 TLSPRGSLLDVATSPAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTD 1195 S S +PA T L LP S PP PP + LR A + Sbjct: 439 GPSAHSSRKPFLGAPAATP-HLSLPPG----PSSPP--PPPCPRLLRPPPPPAWLKGPAC 491 Query: 1196 QAQEKHGE-------SQEGKPCPEDLEQTQQRPLCPRER----PRHNFPV------VRSL 1238 +A + GE EG P P PL RE P F V Sbjct: 492 RAAREDGEILEELFFGTEGPPRPAP------PPLPHREGFLGPPASRFSVGTQDSHTPPT 545 Query: 1239 PPPVHRHSVSGFSEPVGRRPGGPQSLTPLP-------AYPATQKVLQDPQSGEYFVFDLP 1291 PP S + S P GP S P P P Q+PQ L Sbjct: 546 PPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLA 605 Query: 1292 L---------QVKIKTFYDPETGKYVKVSIPSSEGASPEPPPPDALAAPYVLYPGFQPVP 1342 L Q +F PE+ + +VS P + P PPP AP + PG +P Sbjct: 606 LPPAPPSSCHQNTSGSFRRPESPR-PRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELP 664 >gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f [Homo sapiens] Length = 1412 Score = 45.4 bits (106), Expect = 4e-04 Identities = 103/457 (22%), Positives = 153/457 (33%), Gaps = 91/457 (19%) Query: 884 SLSSGHKEEELPRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSS 943 S S +EEE E + A N +LG P++ +K A E G+ + Sbjct: 83 STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS-----MKEKAKAETEKAGKTGN 137 Query: 944 MARMEASQPAPK-GNFPSMPLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIP 1002 S P P G + L G+ R A P A LV+ + GS + AA + Sbjct: 138 ------SMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMV 191 Query: 1003 TIALPEGDIEDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSP 1062 + + ED S T +++ A++P G+P Sbjct: 192 SAGQADSSSEDT-----------------SSSSDETDVEVKASEKILQVRAASAPAKGTP 234 Query: 1063 GESSACSPAASNIWEESSQAPGGPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGG 1122 G+ + +P +SQ G PEE +++S SS T Sbjct: 235 GKGATPAP-PGKAGAVASQTKAGK---PEEDSESSSEESSDSEEET------------PA 278 Query: 1123 SDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELPAQLERTASKPPAVPPKTEKALR 1182 + LL+ A S + S + A++PA S R PA P KT A+ Sbjct: 279 AKALLQAKA------SGKTSQVGAASAPAKESPR----------KGAAPAPPGKTGPAV- 321 Query: 1183 RAKKLASKRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPV 1242 AK A KR + Q+ + +S+E P + +P P VR+ P Sbjct: 322 -AKAQAGKREEDSQSSSEESDSEEEAPA--------------QAKPSGKAPQVRAASAPA 366 Query: 1243 HRHSVSGFSEPVGRRPGGPQSLTPLPAYPATQKVLQDPQ-SGEYFVFDLPLQVKIKTFYD 1301 S G P P+ P A K +D + S E D + Sbjct: 367 KE------SPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQV 420 Query: 1302 PETGKYVKVSI-------PSSEGASPEPPPPDALAAP 1331 GK +V P +GA P PP A P Sbjct: 421 KPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATP 457 >gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo sapiens] Length = 1411 Score = 45.4 bits (106), Expect = 4e-04 Identities = 103/457 (22%), Positives = 153/457 (33%), Gaps = 91/457 (19%) Query: 884 SLSSGHKEEELPRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSS 943 S S +EEE E + A N +LG P++ +K A E G+ + Sbjct: 83 STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS-----MKEKAKAETEKAGKTGN 137 Query: 944 MARMEASQPAPK-GNFPSMPLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIP 1002 S P P G + L G+ R A P A LV+ + GS + AA + Sbjct: 138 ------SMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMV 191 Query: 1003 TIALPEGDIEDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSP 1062 + + ED S T +++ A++P G+P Sbjct: 192 SAGQADSSSEDT-----------------SSSSDETDVEVKASEKILQVRAASAPAKGTP 234 Query: 1063 GESSACSPAASNIWEESSQAPGGPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGG 1122 G+ + +P +SQ G PEE +++S SS T Sbjct: 235 GKGATPAP-PGKAGAVASQTKAGK---PEEDSESSSEESSDSEEET------------PA 278 Query: 1123 SDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELPAQLERTASKPPAVPPKTEKALR 1182 + LL+ A S + S + A++PA S R PA P KT A+ Sbjct: 279 AKALLQAKA------SGKTSQVGAASAPAKESPR----------KGAAPAPPGKTGPAV- 321 Query: 1183 RAKKLASKRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPV 1242 AK A KR + Q+ + +S+E P + +P P VR+ P Sbjct: 322 -AKAQAGKREEDSQSSSEESDSEEEAPA--------------QAKPSGKAPQVRAASAPA 366 Query: 1243 HRHSVSGFSEPVGRRPGGPQSLTPLPAYPATQKVLQDPQ-SGEYFVFDLPLQVKIKTFYD 1301 S G P P+ P A K +D + S E D + Sbjct: 367 KE------SPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQV 420 Query: 1302 PETGKYVKVSI-------PSSEGASPEPPPPDALAAP 1331 GK +V P +GA P PP A P Sbjct: 421 KPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATP 457 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 45.1 bits (105), Expect = 5e-04 Identities = 128/542 (23%), Positives = 177/542 (32%), Gaps = 70/542 (12%) Query: 903 PGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQ-GSSMARMEASQPAPKGNFPSM 961 P C E+ G S +++GT + + P G S++ P KG+ Sbjct: 767 PKECPTEDS---GASATASSKGT-----LTYLADSPSPLGVSVSPQTKRPPTKKGSAGPD 818 Query: 962 PLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIPTIALPEG-DIEDQPPPWQP 1020 +G +P +A+ S GS DS A H PT P+G P P Sbjct: 819 TPIGNLSSPVSPVEASFLPENSLSFQGSKDS---PATTHSPTPPSPKGAPTPSAVTPLSP 875 Query: 1021 ENCW--EEQTPGFKSHFLSTPRAGP--PGRRLVPSERANSPNPGSPGESSACSPAASNIW 1076 + ++TP L P+ GP P + P+ S +P + + +PA I Sbjct: 876 KGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSP----KKARATPAPKGIP 931 Query: 1077 EESSQ--APGGPELLPEEPN--QASP---WASSSPARVTRREDLTHALVWEGGSDPLLEL 1129 S AP P P P A+P WA + PA A G+ Sbjct: 932 ASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAA 991 Query: 1130 SAEDLR----TLSPRGSLLDVATSPAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAK 1185 + + T SP+G+ A +P G + AS PPA P + K A Sbjct: 992 TPPSPKGGPATPSPKGAPTPPAVTPPSPKGS-PAATPFPKGASTPPAATPPSPKGSPAAT 1050 Query: 1186 KLASKRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLC----PRERPRHNFPVVRSLPPP 1241 L T A S +G P L+ P P+ P P +PP Sbjct: 1051 PLPKGAPTTPAATLP---SPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPA 1107 Query: 1242 VHRHSVSG-FSEPVGRRPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFY 1300 S G + P + G P + P P P+ P K Sbjct: 1108 ATPPSPKGGLATPPHK--GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT 1165 Query: 1301 DPETGKYVKVSIPSSEGASPEPPPPDALAAPYVLYPGFQPVPVTALMP-----LRCSSQL 1355 P G P++ A+P P P LA P P P A P L S Sbjct: 1166 PPPKGA------PTTPAATP-PSPKGGLATPS---PKGAPTTPAATPPSPKGGLATPSPK 1215 Query: 1356 SAPTFLRQGPRASAARARTQSVHESGLQLDPGPHG-DCTPHSAGQRPHGPPQSPGEEGVE 1414 APT A T + GL P P G TP + P G P +P +G Sbjct: 1216 GAPT----------TPAATPPSPKGGLAT-PSPKGAPTTPAATPPSPKGGPATPPPKGAP 1264 Query: 1415 AP 1416 P Sbjct: 1265 TP 1266 Score = 40.8 bits (94), Expect = 0.009 Identities = 76/355 (21%), Positives = 112/355 (31%), Gaps = 49/355 (13%) Query: 949 ASQPAPKGNFPSMPLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIPTIALPE 1008 A+ P+PKG + P G A P + G +A+ G+ + P P+ Sbjct: 1108 ATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP-------SPK 1160 Query: 1009 GDIEDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPG--SPGESS 1066 G + PP P TP L+TP P G P+ SP G +P Sbjct: 1161 GGLATPPPKGAPTT--PAATPPSPKGGLATP--SPKGAPTTPAATPPSPKGGLATPSPKG 1216 Query: 1067 A-CSPAASNIWEESSQAPGGPELLPEEPNQASPWASSSPARVTRREDLTHALV------- 1118 A +PAA+ + A P+ P P P PA + T Sbjct: 1217 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKG 1276 Query: 1119 ------WEGGSDPLLELSAEDL---RTLSPRGSLLDVATSPAGTSGRLELPAQLERTASK 1169 +G +P + T P+G+ A +P G P + A Sbjct: 1277 GLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPP--PKGAPT 1334 Query: 1170 PPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRERPR 1229 PPAV P + K T S+ G P +++ P P P Sbjct: 1335 PPAVTPPSPKG-------------TPTLPATTPSSKGGPTTP----SSKEGPTPPAATPS 1377 Query: 1230 HNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPAYPATQKVLQDPQSGE 1284 H + P P ++ P S PA P T++ P G+ Sbjct: 1378 HKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGD 1432 Score = 38.1 bits (87), Expect = 0.061 Identities = 90/404 (22%), Positives = 135/404 (33%), Gaps = 50/404 (12%) Query: 949 ASQPAPKGNFPSMPLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIPTIALPE 1008 A+ P+PKG + G A P + G +A+ G+ + P P+ Sbjct: 1200 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP-------SPK 1252 Query: 1009 GDIEDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLV--PSER---ANSPNPGSPG 1063 G PP P P K + P G P +V PS + A SP G+P Sbjct: 1253 GGPATPPPKGAPTPP-AATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPT 1311 Query: 1064 ESSAC--SPAASNIWEESSQAPGGPELLPEEPNQASPWASSSPARVTRREDLTHALVWEG 1121 +A SP S AP P + P P +++P + + T EG Sbjct: 1312 PPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTP---SSKGGPTTPSSKEG 1368 Query: 1122 GSDPLLELSAEDLRTLSP----RGSLLDVATSPAGTSGRLELPAQLERTASKPPAVPPKT 1177 + P S + ++P RG + SP G PA + + K PA P Sbjct: 1369 PTPPAATPSHKGGPAMTPPSPKRGPAI---PSPKGDP---TSPAVIPLSPKKAPATPVTR 1422 Query: 1178 EKALRRAKKLASKRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRERPRHNFPVVRS 1237 E A +K + T + +K + K P ++ P P P P + Sbjct: 1423 EGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPA-TPSSKGDPTLPAVTP----PSPKE 1477 Query: 1238 LPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPA--------YPATQKVLQDP--QSGEYFV 1287 PP + + S P LPA PAT +DP + Sbjct: 1478 --PPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLS 1535 Query: 1288 FDLPLQVKIKTFYDPETGKYVKVSIPSSEGASPEPPPPDALAAP 1331 P + K P +++PS + P P +A A P Sbjct: 1536 KKTPATLAPKEALIPPA-----MTVPSPKKTPAIPTPKEAPATP 1574 Score = 33.5 bits (75), Expect = 1.5 Identities = 96/489 (19%), Positives = 155/489 (31%), Gaps = 49/489 (10%) Query: 952 PAPKGNFPSMPLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIPTIALPEGDI 1011 P+PKG + P G A P + G + G+ + P T LP Sbjct: 1295 PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTP 1354 Query: 1012 EDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPG--ESSACS 1069 + P P + P P PP + P+ + +P SP S Sbjct: 1355 SSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKK 1414 Query: 1070 PAASNIWEESSQAPGGPELLP---------EEPNQASPWASSSPARVTRREDLTHALVWE 1120 A+ + E + P +L P + P ++P PA + + D T V Sbjct: 1415 APATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAP--KGGPATPSSKGDPTLPAV-- 1470 Query: 1121 GGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELPAQLERTASKPPAVPPKTEKA 1180 P + ++ S +PA G LPA + + + PA P Sbjct: 1471 ---TPPSPKEPPAPKQVATSSSPKKAPATPA-PMGAPTLPAVIPSSPKEVPATPSSRRDP 1526 Query: 1181 LRRAKKLASKRRKTDQA-QEKHGESQEGKPCPED---LEQTQQRPLCPRERPRHNFPVV- 1235 + L SK+ A +E P P+ + ++ P P + + P V Sbjct: 1527 IAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVT 1586 Query: 1236 ----RSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPL-----PAYPATQKVLQDPQSGEYF 1286 + P P + P + P ++TP PA PA + P Sbjct: 1587 PSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSS 1646 Query: 1287 VFDLPLQVKIKTFYDPETGKYVKVSIPSSEG--------ASPEPPPPDALAAPYVLYPGF 1338 + D P T T +P+ +G +P P + AP G Sbjct: 1647 LKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAP--TRKGP 1704 Query: 1339 QPVPVTALMPLRCSSQLSAPTFLRQGPRASAARARTQSVHESGLQLDPGPHGDCTPHSAG 1398 Q +A P C + +GP ++ A A V + + G +P Sbjct: 1705 QTKKSSATSPPICPDPSAKNG--SKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSP---- 1758 Query: 1399 QRPHGPPQS 1407 + P PP+S Sbjct: 1759 KGPLAPPES 1767 >gi|33667044 ABI gene family, member 3 (NESH) binding protein [Homo sapiens] Length = 1075 Score = 43.9 bits (102), Expect = 0.001 Identities = 71/332 (21%), Positives = 110/332 (33%), Gaps = 67/332 (20%) Query: 1131 AEDLRTLSPRGSLLDVATSPAGTSGRLELPAQLERTASKP-PAVPPKTEKALRRAKK-LA 1188 +ED + L P+ + DV +SP TS E+ T+ + ++PPKT + L + + LA Sbjct: 376 SEDSKVLQPQTATYDVFSSPT-TSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLA 434 Query: 1189 SKRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRERPRHN---------------FP 1233 + + S E +P +QT P P+ RPR P Sbjct: 435 PSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITP 494 Query: 1234 VVRSLPPPVHRHSVSGFSEPVGRRPGGPQS---------------------LTPLPAYPA 1272 + P P G ++ + +P P S +P P P Sbjct: 495 KISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQ 554 Query: 1273 TQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSI-------PSSEGASPEPPPP 1325 TQ V + PQ + K KT PE P E + EP P Sbjct: 555 TQPVPKVPQR---------VTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPL 605 Query: 1326 DALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASAARARTQSVHESGLQLD 1385 + P++ P L + Q + F + PR + TQ+ H + Sbjct: 606 ETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVR 665 Query: 1386 PGPHGDCTPHSAGQRPH---GPPQSPGEEGVE 1414 P +PH G Q+P G + Sbjct: 666 P---------RTSDKPHIRPGVKQAPRPSGAD 688 >gi|18079216 CASK interacting protein 1 [Homo sapiens] Length = 1431 Score = 43.5 bits (101), Expect = 0.001 Identities = 44/142 (30%), Positives = 58/142 (40%), Gaps = 20/142 (14%) Query: 1160 PAQLERTASKPPA-VPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKPCPED----- 1213 PA++ T KP + +PP R+ L + R +QE G+ G P Sbjct: 668 PAEVGPTTEKPSSHLPPTPRATTRQDSSLGGRARHMSSSQELLGDGPPGPSSPMSRSQEY 727 Query: 1214 -LEQTQQRPLCPRE-RP-RHNFPVVRSLPPPVHRH-------SVSGFS---EPVGRRPGG 1260 L++ PRE RP RH + R+ PPV S F+ P RPG Sbjct: 728 LLDEGPAPGTPPREARPGRHGHSIKRASVPPVPGKPRQVLPPGTSHFTPPQTPTKTRPGS 787 Query: 1261 PQSL-TPLPAYPATQKVLQDPQ 1281 PQ+L P PAT KV PQ Sbjct: 788 PQALGGPHGPAPATAKVKPTPQ 809 Score = 40.4 bits (93), Expect = 0.012 Identities = 151/614 (24%), Positives = 201/614 (32%), Gaps = 135/614 (21%) Query: 864 ATPVIKP---IMLPLLRTMS---LEDSLSSGHKEEELPRPEWGEDPGFCAPENQDILGTS 917 AT +KP ++ P R MS L S + LP+P GE G AP G + Sbjct: 800 ATAKVKPTPQLLPPTERPMSPRSLPQSPTHRGFAYVLPQPVEGE-VGPAAP------GPA 852 Query: 918 TPTNTRGTRVKCMANEVMEDPGQ----GSSMARMEASQPAPKGNFPSMPL---------- 963 P C+ E +PG+ S+ R AS P+ + +P Sbjct: 853 PPPVPTAVPTLCLPPEADAEPGRPKKRAHSLNRYAASDSEPERDELLVPAAAGPYATVQR 912 Query: 964 -VGEGDRVKAPPDAAPGLVASNCKS-GSADSGKLAAPWHIPTIALPEGDIEDQP-PPWQP 1020 VG V+AP A + S + G P + AL ++ D+P P +P Sbjct: 913 RVGRSHSVRAPAGADKNVNRSQSFAVRPRKKGPPPPPPKRSSSALASANLADEPVPDAEP 972 Query: 1021 ENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPG--ESSACSPAASNIWEE 1078 E+ G RA S+ A S + GS G +S A S+I Sbjct: 973 ED-------GLLGVRAQCRRA---------SDLAGSVDTGSAGSVKSIAAMLELSSIGGG 1016 Query: 1079 SSQAPGGPELLPEEPNQASPWASSSPARV-TRREDLTHALVWEGGSDPLLELSAEDLRTL 1137 A PE P P ASP P RV T + H G + + RTL Sbjct: 1017 GRAARRPPEGHPT-PRPASP----EPGRVATVLASVKHKEAIGPGGEVV-----NRRRTL 1066 Query: 1138 S-PRGSLLDVATSPAGTSG-------------RLELPAQLERTASKPPAVPPKTEKALRR 1183 S P LL A G S R P++ E PP + L+R Sbjct: 1067 SGPVTGLLATARRGPGESADPGPFVEDGTGRQRPRGPSKGEAGVEGPPLAKVEASATLKR 1126 Query: 1184 AKKLASKRRK----------TDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRERPRHNFP 1233 + +++ T + + K E + G P L R RP Sbjct: 1127 RIRAKQNQQENVKFILTESDTVKRRPKAKEREAGPEPPPPLSVYHNGTGTVRRRPASEQA 1186 Query: 1234 VVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQ 1293 LPPP P P P L LP P + + P + Q Sbjct: 1187 GPPELPPP----------PPPAEPP--PTDLAHLPPLPPPEGEARKPAKPPVSPKPVLTQ 1234 Query: 1294 VKIKTFYDPE-TGKYVKVSIPSSEGA----------SPEPPPPDALAAPYVLYPGFQPVP 1342 K P T K V + P S SP+PPPP AP +PV Sbjct: 1235 PVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPP--TAP-------KPVK 1285 Query: 1343 VTALMPLRCSSQLSAPTFLRQGPRASAARARTQSVHESGLQLDPGPHGDCTPHSAGQRPH 1402 A +P + AP+ RQ P A L PG TP S G P Sbjct: 1286 AVAGLPSGSAGPSPAPSPARQPPAA--------------LAKPPG-----TPPSLGASPA 1326 Query: 1403 GPPQSPGEEGVEAP 1416 PP SPG + P Sbjct: 1327 KPP-SPGAPALHVP 1339 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 43.1 bits (100), Expect = 0.002 Identities = 72/323 (22%), Positives = 113/323 (34%), Gaps = 41/323 (12%) Query: 893 ELPRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQP 952 E P P E+P AP +TP T K A ++P + E + Sbjct: 520 EEPTPTTPEEP---APTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK---ETAPT 573 Query: 953 APKGNFPSMPLVGEGDRVK--APPDAAPGLV----ASNCKSGSADSGKLAAPWHIPTIAL 1006 PKG P+ K AP + AP ++ C + + K AP T Sbjct: 574 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP---TTPKE 630 Query: 1007 PEGDIEDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVP-------SERANSPNP 1059 P +P P P+ K +TP+ P + L P S ++ P P Sbjct: 631 PAPTTPKEPAPTTPKGT---APTTLKEPAPTTPKKPAP-KELAPTTTKGPTSTTSDKPAP 686 Query: 1060 GSPGESSACSPAASNIWEESSQAPGGPELLPEEPNQAS-PWASSSPARVTRREDLTHALV 1118 +P E++ +P AP PE P ++ S P + P + + D Sbjct: 687 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPD------ 740 Query: 1119 WEGGSDPLLELSAEDLRTL---SPRGSLLDVATSPAGTSGRLELPAQLERTASKPPAVPP 1175 + ELSAE SP+ + +PA T + A+ + T P Sbjct: 741 -----ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE 795 Query: 1176 KTEKALRRAKKLASKRRKTDQAQ 1198 T A + K+ A+ KT +++ Sbjct: 796 TTTAAPKMTKETATTTEKTTESK 818 Score = 40.8 bits (94), Expect = 0.009 Identities = 83/407 (20%), Positives = 128/407 (31%), Gaps = 53/407 (13%) Query: 209 SYQPGRKHGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGT 268 S++ GR+ K + C SF D K P+P PV E G G Sbjct: 36 SFERGRECDCDAQCKKYDKCCPDYESFCAEVKDNKKNRTKKKPTPK-PPVVDEAGSG--- 91 Query: 269 FLHSENSAFESWNAHQPKLLERKDTAGTVPESKAPKHYGDTTLLREPCPPERTVSPCQVQ 328 L+ D T P++ +H +T P T P + Sbjct: 92 -------------------LDNGDFKVTTPDTSTTQHNKVST-----SPKITTAKPINPR 127 Query: 329 ASCSQEENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPSSQPDSQEKP--AQPPWRKPKT 386 S + +L+ + ++ + + D +EK A+ KT Sbjct: 128 PSLPPNSDTSKETSLTVN-----KETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 182 Query: 387 GKKGKESLQDTLEE---KTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNI 443 K L + K +T +GP L T P + A P EP P Sbjct: 183 SAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT----PTTIK 238 Query: 444 SKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNL 503 S TP P+ SA + P E P+ + KEP+ +++ + S Sbjct: 239 SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 298 Query: 504 KD----VRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESPPNELSKE 559 K+ K+ T P E T K+ + P +E P K Sbjct: 299 KEPAPTTPKKPAPTTPKEPAPTTPKEPT--PTTPKEPAPTTKEPAPTTPKEPAPTAPKKP 356 Query: 560 RPADDPTASHINPQKD-PTA----DPSEPSADSYLTLSTAPTIAKAP 601 P + P++ PT P+ P + T +APT K P Sbjct: 357 APTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 403 Score = 38.5 bits (88), Expect = 0.047 Identities = 69/347 (19%), Positives = 111/347 (31%), Gaps = 23/347 (6%) Query: 1025 EEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPG 1084 +E TP +TP+ P P P + E + +P AP Sbjct: 230 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 289 Query: 1085 GPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLEL-SAEDLRTLSPRGSL 1143 + P P + +P PA T +E + P + ++ +P+ Sbjct: 290 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 349 Query: 1144 LDVATSPAGTSGRLELPAQLER---TASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEK 1200 PA T+ + P + T +K P+ E A K + ++ K Sbjct: 350 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 409 Query: 1201 HGESQEGKPCPEDLEQTQQRPLCPRE----RPRHNFPVVRSLPPPV--HRHSVSGFSEPV 1254 + +P P + + P P+E P+ P P P + + +P Sbjct: 410 SAPTTPKEPSPTTTK--EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 467 Query: 1255 GRRPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPS 1314 P P TP P T K L P + E P + P T + + + P Sbjct: 468 PTTPKEPAPTTPKETAPTTPKKL-TPTTPEKLAPTTPEKPA------PTTPEELAPTTP- 519 Query: 1315 SEGASPEPPPPDALAAPYVLYPGF--QPVPVTALMPLRCSSQLSAPT 1359 E +P P A P P +P P T P + + APT Sbjct: 520 -EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 565 Score = 38.1 bits (87), Expect = 0.061 Identities = 106/545 (19%), Positives = 168/545 (30%), Gaps = 51/545 (9%) Query: 96 AATFQQLPKYVQGEEKYPKTSPPPTPVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTES 155 A T + P +E P T PTP + P + + P Sbjct: 302 APTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK--------------- 346 Query: 156 QRCESRPTASKPPALKNPPKFAPLPENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRK 215 E PTA K PA P + AP + A T + E S T P Sbjct: 347 ---EPAPTAPKKPAPTTPKEPAPTTPK------EPAPTTTK----EPSPTTPKEPAPTTT 393 Query: 216 HGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENS 275 ++K P S+ P + T + P+ +P P + T Sbjct: 394 KSAPTTTKEPAPTTTKSAPTTP-KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 452 Query: 276 AFESWNAHQPKLLERKDTAGTVPESKA---PKHYGDTTLLR-EPCPPERTVSPCQVQASC 331 +P K A T P+ A PK TT + P PE+ ++P + Sbjct: 453 T----TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK-LAPTTPEKPA 507 Query: 332 SQEENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPSSQPDSQEKPAQPPWRKPKTGKKGK 391 LA P +P ++ P++ ++PA P K K Sbjct: 508 PTTPEELAPTTPEEPTPTTPEEPAPTT------PKAAAPNTPKEPA-PTTPKEPAPTTPK 560 Query: 392 ESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISKLLTPII 451 E T +E T +G T P + A + P +P P Sbjct: 561 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKEPTSTTCDKPAPTT 619 Query: 452 PSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLKDVRKRVK 511 P K + +PA TP P + P+ + K P+ K Sbjct: 620 P-KGTAPTTPKEPAPTTPKEPAPTTP-KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPT 677 Query: 512 STYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESPP--NELSKERPADDPTASH 569 ST S P ++T + P + P E PP +E+S +PT H Sbjct: 678 STTSDKP-APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 736 Query: 570 INPQKDPTADPSEPSADSYLTLSTAPTIAKAPFYVNGEAAERSSYENKEVEGELEMGPAG 629 +P + +EP+ + P + + ++ ++K E +L P Sbjct: 737 KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPET 796 Query: 630 SSWCP 634 ++ P Sbjct: 797 TTAAP 801 Score = 38.1 bits (87), Expect = 0.061 Identities = 107/521 (20%), Positives = 157/521 (30%), Gaps = 73/521 (14%) Query: 96 AATFQQLPKYVQGEEKYPKTSPPPTPVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTES 155 A T + P +E P T P P + P + + T K T + Sbjct: 349 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 408 Query: 156 QRC-----ESRPTASKPPALKNPPKFAP-LPENSVNFCFDSAFLTVRRVPAEVSNTHQNS 209 + E PT +K PA P + AP P+ T + PA + Sbjct: 409 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT----- 463 Query: 210 YQPGRKHGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGTF 269 K + K P ++ T T E P+ KP P T Sbjct: 464 -----KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT- 517 Query: 270 LHSENSAFESWNAHQPKLLERKDTAGTVPESKAPKHYGD--TTLLREPCP-PERTVSPCQ 326 +P ++ A T P++ AP + T +EP P + +P Sbjct: 518 -----------TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 566 Query: 327 VQASCSQEENRLAAGALSTSIPWGCRDPGAQVFA-VEGKAPSSQPDSQEKPAQPPWRKPK 385 + + A L P + P + A K P+S + P P P Sbjct: 567 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT 626 Query: 386 TGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISK 445 T KE T +E T +G T P + A + P P S Sbjct: 627 T---PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSD 682 Query: 446 LLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLKD 505 P P K + +PA TP P + P+ + +K P+ + Sbjct: 683 KPAPTTP-KETAPTTPKEPAPTTPKKPAPTTP-ETPPPTTSEVSTPTTTKEPTTIH---- 736 Query: 506 VRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESP--PNELSKERPAD 563 KS S+P L EP P LE SP P + + PA Sbjct: 737 -----KSPDESTPELSA-------------EPT------PKALENSPKEPGVPTTKTPAA 772 Query: 564 -----DPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAK 599 TA ++D P +A +T TA T K Sbjct: 773 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK 813 Score = 38.1 bits (87), Expect = 0.061 Identities = 87/425 (20%), Positives = 134/425 (31%), Gaps = 53/425 (12%) Query: 895 PRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAP 954 P P ++P P+ T + T P + S E + P Sbjct: 372 PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 431 Query: 955 KGNFPSMPLVGEGDRVKAPPDAAPGLVA-SNCKSGSADSGKLAAPWH----IPTI----- 1004 K P+ P K P P A + K + + K AP PT Sbjct: 432 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 491 Query: 1005 -ALPEG---DIEDQPPPWQPENCW----EEQTPGFKSHFL-STPRAGPPGRRLVPSERA- 1054 PE ++P P PE EE TP +TP+A P P+ Sbjct: 492 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 551 Query: 1055 --------NSPNPGSPGESSACSP---AASNIWEESSQAPGGP---ELLPEEPNQASPWA 1100 P P +P E++ +P A + + E + P P EL P + + Sbjct: 552 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 611 Query: 1101 SSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELP 1160 PA T + +P E T +P+G+ PA T+ + P Sbjct: 612 CDKPAPTTPKGTAPTT-----PKEPAPTTPKEPAPT-TPKGTAPTTLKEPAPTTPKKPAP 665 Query: 1161 AQLERTASKPPAVPPKTEKALRRAKKLA--SKRRKTDQAQEKHGESQEGKPCPEDLE--- 1215 +L T +K P + A K+ A + + +K + P P E Sbjct: 666 KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 725 Query: 1216 -QTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPAYPATQ 1274 T + P + P + P + + P P E + PG P + TP P Sbjct: 726 PTTTKEPTTIHKSPDESTPELSAEPTP-------KALENSPKEPGVPTTKTPAATKPEMT 778 Query: 1275 KVLQD 1279 +D Sbjct: 779 TTAKD 783 Score = 35.0 bits (79), Expect = 0.52 Identities = 64/281 (22%), Positives = 86/281 (30%), Gaps = 36/281 (12%) Query: 1151 AGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQE-KHGESQEGKP 1209 A TS L P T +K PA+ E K+ AS K K + +P Sbjct: 188 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 247 Query: 1210 CPEDLEQTQQRPLCPRE------------RPRHNFPVVRSLPPPVHRHSVSGF-SEPVGR 1256 P T+ P P+E P+ P P P S EP Sbjct: 248 APTT---TKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 304 Query: 1257 RPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPSSE 1316 P P TP P T K +P P K P T + + Sbjct: 305 TPKKPAPTTPKEPAPTTPK---EPT---------PTTPKEPA---PTTKEPAPTTPKEPA 349 Query: 1317 GASPEPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASAARARTQS 1376 +P+ P P P P +P P T P + + APT + P + A T + Sbjct: 350 PTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 408 Query: 1377 VHESGLQLDPGPHGDCTPHSAGQRPHGP-PQSPGEEGVEAP 1416 +P P T A P P P +P + P Sbjct: 409 KSAPTTPKEPSP--TTTKEPAPTTPKEPAPTTPKKPAPTTP 447 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 43.1 bits (100), Expect = 0.002 Identities = 72/323 (22%), Positives = 113/323 (34%), Gaps = 41/323 (12%) Query: 893 ELPRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQP 952 E P P E+P AP +TP T K A ++P + E + Sbjct: 561 EEPTPTTPEEP---APTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK---ETAPT 614 Query: 953 APKGNFPSMPLVGEGDRVK--APPDAAPGLV----ASNCKSGSADSGKLAAPWHIPTIAL 1006 PKG P+ K AP + AP ++ C + + K AP T Sbjct: 615 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP---TTPKE 671 Query: 1007 PEGDIEDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVP-------SERANSPNP 1059 P +P P P+ K +TP+ P + L P S ++ P P Sbjct: 672 PAPTTPKEPAPTTPKGT---APTTLKEPAPTTPKKPAP-KELAPTTTKGPTSTTSDKPAP 727 Query: 1060 GSPGESSACSPAASNIWEESSQAPGGPELLPEEPNQAS-PWASSSPARVTRREDLTHALV 1118 +P E++ +P AP PE P ++ S P + P + + D Sbjct: 728 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPD------ 781 Query: 1119 WEGGSDPLLELSAEDLRTL---SPRGSLLDVATSPAGTSGRLELPAQLERTASKPPAVPP 1175 + ELSAE SP+ + +PA T + A+ + T P Sbjct: 782 -----ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE 836 Query: 1176 KTEKALRRAKKLASKRRKTDQAQ 1198 T A + K+ A+ KT +++ Sbjct: 837 TTTAAPKMTKETATTTEKTTESK 859 Score = 40.8 bits (94), Expect = 0.009 Identities = 83/407 (20%), Positives = 128/407 (31%), Gaps = 53/407 (13%) Query: 209 SYQPGRKHGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGT 268 S++ GR+ K + C SF D K P+P PV E G G Sbjct: 77 SFERGRECDCDAQCKKYDKCCPDYESFCAEVKDNKKNRTKKKPTPK-PPVVDEAGSG--- 132 Query: 269 FLHSENSAFESWNAHQPKLLERKDTAGTVPESKAPKHYGDTTLLREPCPPERTVSPCQVQ 328 L+ D T P++ +H +T P T P + Sbjct: 133 -------------------LDNGDFKVTTPDTSTTQHNKVST-----SPKITTAKPINPR 168 Query: 329 ASCSQEENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPSSQPDSQEKP--AQPPWRKPKT 386 S + +L+ + ++ + + D +EK A+ KT Sbjct: 169 PSLPPNSDTSKETSLTVN-----KETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 223 Query: 387 GKKGKESLQDTLEE---KTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNI 443 K L + K +T +GP L T P + A P EP P Sbjct: 224 SAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT----PTTIK 279 Query: 444 SKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNL 503 S TP P+ SA + P E P+ + KEP+ +++ + S Sbjct: 280 SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 339 Query: 504 KD----VRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESPPNELSKE 559 K+ K+ T P E T K+ + P +E P K Sbjct: 340 KEPAPTTPKKPAPTTPKEPAPTTPKEPT--PTTPKEPAPTTKEPAPTTPKEPAPTAPKKP 397 Query: 560 RPADDPTASHINPQKD-PTA----DPSEPSADSYLTLSTAPTIAKAP 601 P + P++ PT P+ P + T +APT K P Sbjct: 398 APTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 444 Score = 38.5 bits (88), Expect = 0.047 Identities = 69/347 (19%), Positives = 111/347 (31%), Gaps = 23/347 (6%) Query: 1025 EEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPG 1084 +E TP +TP+ P P P + E + +P AP Sbjct: 271 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 330 Query: 1085 GPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLEL-SAEDLRTLSPRGSL 1143 + P P + +P PA T +E + P + ++ +P+ Sbjct: 331 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 390 Query: 1144 LDVATSPAGTSGRLELPAQLER---TASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEK 1200 PA T+ + P + T +K P+ E A K + ++ K Sbjct: 391 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 450 Query: 1201 HGESQEGKPCPEDLEQTQQRPLCPRE----RPRHNFPVVRSLPPPV--HRHSVSGFSEPV 1254 + +P P + + P P+E P+ P P P + + +P Sbjct: 451 SAPTTPKEPSPTTTK--EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 508 Query: 1255 GRRPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPS 1314 P P TP P T K L P + E P + P T + + + P Sbjct: 509 PTTPKEPAPTTPKETAPTTPKKL-TPTTPEKLAPTTPEKPA------PTTPEELAPTTP- 560 Query: 1315 SEGASPEPPPPDALAAPYVLYPGF--QPVPVTALMPLRCSSQLSAPT 1359 E +P P A P P +P P T P + + APT Sbjct: 561 -EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 606 Score = 38.1 bits (87), Expect = 0.061 Identities = 106/545 (19%), Positives = 168/545 (30%), Gaps = 51/545 (9%) Query: 96 AATFQQLPKYVQGEEKYPKTSPPPTPVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTES 155 A T + P +E P T PTP + P + + P Sbjct: 343 APTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK--------------- 387 Query: 156 QRCESRPTASKPPALKNPPKFAPLPENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRK 215 E PTA K PA P + AP + A T + E S T P Sbjct: 388 ---EPAPTAPKKPAPTTPKEPAPTTPK------EPAPTTTK----EPSPTTPKEPAPTTT 434 Query: 216 HGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENS 275 ++K P S+ P + T + P+ +P P + T Sbjct: 435 KSAPTTTKEPAPTTTKSAPTTP-KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 493 Query: 276 AFESWNAHQPKLLERKDTAGTVPESKA---PKHYGDTTLLR-EPCPPERTVSPCQVQASC 331 +P K A T P+ A PK TT + P PE+ ++P + Sbjct: 494 T----TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK-LAPTTPEKPA 548 Query: 332 SQEENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPSSQPDSQEKPAQPPWRKPKTGKKGK 391 LA P +P ++ P++ ++PA P K K Sbjct: 549 PTTPEELAPTTPEEPTPTTPEEPAPTT------PKAAAPNTPKEPA-PTTPKEPAPTTPK 601 Query: 392 ESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISKLLTPII 451 E T +E T +G T P + A + P +P P Sbjct: 602 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKEPTSTTCDKPAPTT 660 Query: 452 PSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLKDVRKRVK 511 P K + +PA TP P + P+ + K P+ K Sbjct: 661 P-KGTAPTTPKEPAPTTPKEPAPTTP-KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPT 718 Query: 512 STYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESPP--NELSKERPADDPTASH 569 ST S P ++T + P + P E PP +E+S +PT H Sbjct: 719 STTSDKP-APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 777 Query: 570 INPQKDPTADPSEPSADSYLTLSTAPTIAKAPFYVNGEAAERSSYENKEVEGELEMGPAG 629 +P + +EP+ + P + + ++ ++K E +L P Sbjct: 778 KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPET 837 Query: 630 SSWCP 634 ++ P Sbjct: 838 TTAAP 842 Score = 38.1 bits (87), Expect = 0.061 Identities = 107/521 (20%), Positives = 157/521 (30%), Gaps = 73/521 (14%) Query: 96 AATFQQLPKYVQGEEKYPKTSPPPTPVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTES 155 A T + P +E P T P P + P + + T K T + Sbjct: 390 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 449 Query: 156 QRC-----ESRPTASKPPALKNPPKFAP-LPENSVNFCFDSAFLTVRRVPAEVSNTHQNS 209 + E PT +K PA P + AP P+ T + PA + Sbjct: 450 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT----- 504 Query: 210 YQPGRKHGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGTF 269 K + K P ++ T T E P+ KP P T Sbjct: 505 -----KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT- 558 Query: 270 LHSENSAFESWNAHQPKLLERKDTAGTVPESKAPKHYGD--TTLLREPCP-PERTVSPCQ 326 +P ++ A T P++ AP + T +EP P + +P Sbjct: 559 -----------TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 607 Query: 327 VQASCSQEENRLAAGALSTSIPWGCRDPGAQVFA-VEGKAPSSQPDSQEKPAQPPWRKPK 385 + + A L P + P + A K P+S + P P P Sbjct: 608 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT 667 Query: 386 TGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISK 445 T KE T +E T +G T P + A + P P S Sbjct: 668 T---PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSD 723 Query: 446 LLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLKD 505 P P K + +PA TP P + P+ + +K P+ + Sbjct: 724 KPAPTTP-KETAPTTPKEPAPTTPKKPAPTTP-ETPPPTTSEVSTPTTTKEPTTIH---- 777 Query: 506 VRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESP--PNELSKERPAD 563 KS S+P L EP P LE SP P + + PA Sbjct: 778 -----KSPDESTPELSA-------------EPT------PKALENSPKEPGVPTTKTPAA 813 Query: 564 -----DPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAK 599 TA ++D P +A +T TA T K Sbjct: 814 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK 854 Score = 38.1 bits (87), Expect = 0.061 Identities = 87/425 (20%), Positives = 134/425 (31%), Gaps = 53/425 (12%) Query: 895 PRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAP 954 P P ++P P+ T + T P + S E + P Sbjct: 413 PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 472 Query: 955 KGNFPSMPLVGEGDRVKAPPDAAPGLVA-SNCKSGSADSGKLAAPWH----IPTI----- 1004 K P+ P K P P A + K + + K AP PT Sbjct: 473 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 532 Query: 1005 -ALPEG---DIEDQPPPWQPENCW----EEQTPGFKSHFL-STPRAGPPGRRLVPSERA- 1054 PE ++P P PE EE TP +TP+A P P+ Sbjct: 533 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 592 Query: 1055 --------NSPNPGSPGESSACSP---AASNIWEESSQAPGGP---ELLPEEPNQASPWA 1100 P P +P E++ +P A + + E + P P EL P + + Sbjct: 593 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 652 Query: 1101 SSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELP 1160 PA T + +P E T +P+G+ PA T+ + P Sbjct: 653 CDKPAPTTPKGTAPTT-----PKEPAPTTPKEPAPT-TPKGTAPTTLKEPAPTTPKKPAP 706 Query: 1161 AQLERTASKPPAVPPKTEKALRRAKKLA--SKRRKTDQAQEKHGESQEGKPCPEDLE--- 1215 +L T +K P + A K+ A + + +K + P P E Sbjct: 707 KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 766 Query: 1216 -QTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPAYPATQ 1274 T + P + P + P + + P P E + PG P + TP P Sbjct: 767 PTTTKEPTTIHKSPDESTPELSAEPTP-------KALENSPKEPGVPTTKTPAATKPEMT 819 Query: 1275 KVLQD 1279 +D Sbjct: 820 TTAKD 824 Score = 35.0 bits (79), Expect = 0.52 Identities = 64/281 (22%), Positives = 86/281 (30%), Gaps = 36/281 (12%) Query: 1151 AGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQE-KHGESQEGKP 1209 A TS L P T +K PA+ E K+ AS K K + +P Sbjct: 229 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 288 Query: 1210 CPEDLEQTQQRPLCPRE------------RPRHNFPVVRSLPPPVHRHSVSGF-SEPVGR 1256 P T+ P P+E P+ P P P S EP Sbjct: 289 APTT---TKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 345 Query: 1257 RPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPSSE 1316 P P TP P T K +P P K P T + + Sbjct: 346 TPKKPAPTTPKEPAPTTPK---EPT---------PTTPKEPA---PTTKEPAPTTPKEPA 390 Query: 1317 GASPEPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASAARARTQS 1376 +P+ P P P P +P P T P + + APT + P + A T + Sbjct: 391 PTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 449 Query: 1377 VHESGLQLDPGPHGDCTPHSAGQRPHGP-PQSPGEEGVEAP 1416 +P P T A P P P +P + P Sbjct: 450 KSAPTTPKEPSP--TTTKEPAPTTPKEPAPTTPKKPAPTTP 488 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 43.1 bits (100), Expect = 0.002 Identities = 72/323 (22%), Positives = 113/323 (34%), Gaps = 41/323 (12%) Query: 893 ELPRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQP 952 E P P E+P AP +TP T K A ++P + E + Sbjct: 613 EEPTPTTPEEP---APTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK---ETAPT 666 Query: 953 APKGNFPSMPLVGEGDRVK--APPDAAPGLV----ASNCKSGSADSGKLAAPWHIPTIAL 1006 PKG P+ K AP + AP ++ C + + K AP T Sbjct: 667 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP---TTPKE 723 Query: 1007 PEGDIEDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVP-------SERANSPNP 1059 P +P P P+ K +TP+ P + L P S ++ P P Sbjct: 724 PAPTTPKEPAPTTPKGT---APTTLKEPAPTTPKKPAP-KELAPTTTKGPTSTTSDKPAP 779 Query: 1060 GSPGESSACSPAASNIWEESSQAPGGPELLPEEPNQAS-PWASSSPARVTRREDLTHALV 1118 +P E++ +P AP PE P ++ S P + P + + D Sbjct: 780 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPD------ 833 Query: 1119 WEGGSDPLLELSAEDLRTL---SPRGSLLDVATSPAGTSGRLELPAQLERTASKPPAVPP 1175 + ELSAE SP+ + +PA T + A+ + T P Sbjct: 834 -----ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE 888 Query: 1176 KTEKALRRAKKLASKRRKTDQAQ 1198 T A + K+ A+ KT +++ Sbjct: 889 TTTAAPKMTKETATTTEKTTESK 911 Score = 38.5 bits (88), Expect = 0.047 Identities = 69/347 (19%), Positives = 111/347 (31%), Gaps = 23/347 (6%) Query: 1025 EEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPG 1084 +E TP +TP+ P P P + E + +P AP Sbjct: 323 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 382 Query: 1085 GPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLEL-SAEDLRTLSPRGSL 1143 + P P + +P PA T +E + P + ++ +P+ Sbjct: 383 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 442 Query: 1144 LDVATSPAGTSGRLELPAQLER---TASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEK 1200 PA T+ + P + T +K P+ E A K + ++ K Sbjct: 443 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 502 Query: 1201 HGESQEGKPCPEDLEQTQQRPLCPRE----RPRHNFPVVRSLPPPV--HRHSVSGFSEPV 1254 + +P P + + P P+E P+ P P P + + +P Sbjct: 503 SAPTTPKEPSPTTTK--EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 560 Query: 1255 GRRPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPS 1314 P P TP P T K L P + E P + P T + + + P Sbjct: 561 PTTPKEPAPTTPKETAPTTPKKL-TPTTPEKLAPTTPEKPA------PTTPEELAPTTP- 612 Query: 1315 SEGASPEPPPPDALAAPYVLYPGF--QPVPVTALMPLRCSSQLSAPT 1359 E +P P A P P +P P T P + + APT Sbjct: 613 -EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 658 Score = 38.1 bits (87), Expect = 0.061 Identities = 106/545 (19%), Positives = 168/545 (30%), Gaps = 51/545 (9%) Query: 96 AATFQQLPKYVQGEEKYPKTSPPPTPVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTES 155 A T + P +E P T PTP + P + + P Sbjct: 395 APTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK--------------- 439 Query: 156 QRCESRPTASKPPALKNPPKFAPLPENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRK 215 E PTA K PA P + AP + A T + E S T P Sbjct: 440 ---EPAPTAPKKPAPTTPKEPAPTTPK------EPAPTTTK----EPSPTTPKEPAPTTT 486 Query: 216 HGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENS 275 ++K P S+ P + T + P+ +P P + T Sbjct: 487 KSAPTTTKEPAPTTTKSAPTTP-KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 545 Query: 276 AFESWNAHQPKLLERKDTAGTVPESKA---PKHYGDTTLLR-EPCPPERTVSPCQVQASC 331 +P K A T P+ A PK TT + P PE+ ++P + Sbjct: 546 T----TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK-LAPTTPEKPA 600 Query: 332 SQEENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPSSQPDSQEKPAQPPWRKPKTGKKGK 391 LA P +P ++ P++ ++PA P K K Sbjct: 601 PTTPEELAPTTPEEPTPTTPEEPAPTT------PKAAAPNTPKEPA-PTTPKEPAPTTPK 653 Query: 392 ESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISKLLTPII 451 E T +E T +G T P + A + P +P P Sbjct: 654 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKEPTSTTCDKPAPTT 712 Query: 452 PSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLKDVRKRVK 511 P K + +PA TP P + P+ + K P+ K Sbjct: 713 P-KGTAPTTPKEPAPTTPKEPAPTTP-KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPT 770 Query: 512 STYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESPP--NELSKERPADDPTASH 569 ST S P ++T + P + P E PP +E+S +PT H Sbjct: 771 STTSDKP-APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 829 Query: 570 INPQKDPTADPSEPSADSYLTLSTAPTIAKAPFYVNGEAAERSSYENKEVEGELEMGPAG 629 +P + +EP+ + P + + ++ ++K E +L P Sbjct: 830 KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPET 889 Query: 630 SSWCP 634 ++ P Sbjct: 890 TTAAP 894 Score = 38.1 bits (87), Expect = 0.061 Identities = 107/521 (20%), Positives = 157/521 (30%), Gaps = 73/521 (14%) Query: 96 AATFQQLPKYVQGEEKYPKTSPPPTPVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTES 155 A T + P +E P T P P + P + + T K T + Sbjct: 442 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 501 Query: 156 QRC-----ESRPTASKPPALKNPPKFAP-LPENSVNFCFDSAFLTVRRVPAEVSNTHQNS 209 + E PT +K PA P + AP P+ T + PA + Sbjct: 502 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT----- 556 Query: 210 YQPGRKHGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGTF 269 K + K P ++ T T E P+ KP P T Sbjct: 557 -----KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT- 610 Query: 270 LHSENSAFESWNAHQPKLLERKDTAGTVPESKAPKHYGD--TTLLREPCP-PERTVSPCQ 326 +P ++ A T P++ AP + T +EP P + +P Sbjct: 611 -----------TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 659 Query: 327 VQASCSQEENRLAAGALSTSIPWGCRDPGAQVFA-VEGKAPSSQPDSQEKPAQPPWRKPK 385 + + A L P + P + A K P+S + P P P Sbjct: 660 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT 719 Query: 386 TGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISK 445 T KE T +E T +G T P + A + P P S Sbjct: 720 T---PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSD 775 Query: 446 LLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLKD 505 P P K + +PA TP P + P+ + +K P+ + Sbjct: 776 KPAPTTP-KETAPTTPKEPAPTTPKKPAPTTP-ETPPPTTSEVSTPTTTKEPTTIH---- 829 Query: 506 VRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESP--PNELSKERPAD 563 KS S+P L EP P LE SP P + + PA Sbjct: 830 -----KSPDESTPELSA-------------EPT------PKALENSPKEPGVPTTKTPAA 865 Query: 564 -----DPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAK 599 TA ++D P +A +T TA T K Sbjct: 866 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK 906 Score = 38.1 bits (87), Expect = 0.061 Identities = 87/425 (20%), Positives = 134/425 (31%), Gaps = 53/425 (12%) Query: 895 PRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAP 954 P P ++P P+ T + T P + S E + P Sbjct: 465 PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 524 Query: 955 KGNFPSMPLVGEGDRVKAPPDAAPGLVA-SNCKSGSADSGKLAAPWH----IPTI----- 1004 K P+ P K P P A + K + + K AP PT Sbjct: 525 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 584 Query: 1005 -ALPEG---DIEDQPPPWQPENCW----EEQTPGFKSHFL-STPRAGPPGRRLVPSERA- 1054 PE ++P P PE EE TP +TP+A P P+ Sbjct: 585 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 644 Query: 1055 --------NSPNPGSPGESSACSP---AASNIWEESSQAPGGP---ELLPEEPNQASPWA 1100 P P +P E++ +P A + + E + P P EL P + + Sbjct: 645 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 704 Query: 1101 SSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELP 1160 PA T + +P E T +P+G+ PA T+ + P Sbjct: 705 CDKPAPTTPKGTAPTT-----PKEPAPTTPKEPAPT-TPKGTAPTTLKEPAPTTPKKPAP 758 Query: 1161 AQLERTASKPPAVPPKTEKALRRAKKLA--SKRRKTDQAQEKHGESQEGKPCPEDLE--- 1215 +L T +K P + A K+ A + + +K + P P E Sbjct: 759 KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 818 Query: 1216 -QTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPAYPATQ 1274 T + P + P + P + + P P E + PG P + TP P Sbjct: 819 PTTTKEPTTIHKSPDESTPELSAEPTP-------KALENSPKEPGVPTTKTPAATKPEMT 871 Query: 1275 KVLQD 1279 +D Sbjct: 872 TTAKD 876 Score = 37.4 bits (85), Expect = 0.10 Identities = 48/210 (22%), Positives = 71/210 (33%), Gaps = 15/210 (7%) Query: 401 KTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHALDSA 460 K +T +GP L T P + A P EP P S TP P+ SA Sbjct: 293 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT----PTTIKSAPTTPKEPAPTTTKSA 348 Query: 461 DSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLKD----VRKRVKSTYSS 516 + P E P+ + KEP+ +++ + S K+ K+ T Sbjct: 349 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 408 Query: 517 SPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESPPNELSKERPADDPTASHINPQKD- 575 P E T K+ + P +E P K P + P++ Sbjct: 409 EPAPTTPKEPT--PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 466 Query: 576 PTA----DPSEPSADSYLTLSTAPTIAKAP 601 PT P+ P + T +APT K P Sbjct: 467 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 496 Score = 35.0 bits (79), Expect = 0.52 Identities = 64/281 (22%), Positives = 86/281 (30%), Gaps = 36/281 (12%) Query: 1151 AGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQE-KHGESQEGKP 1209 A TS L P T +K PA+ E K+ AS K K + +P Sbjct: 281 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 340 Query: 1210 CPEDLEQTQQRPLCPRE------------RPRHNFPVVRSLPPPVHRHSVSGF-SEPVGR 1256 P T+ P P+E P+ P P P S EP Sbjct: 341 APTT---TKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 397 Query: 1257 RPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPSSE 1316 P P TP P T K +P P K P T + + Sbjct: 398 TPKKPAPTTPKEPAPTTPK---EPT---------PTTPKEPA---PTTKEPAPTTPKEPA 442 Query: 1317 GASPEPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASAARARTQS 1376 +P+ P P P P +P P T P + + APT + P + A T + Sbjct: 443 PTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 501 Query: 1377 VHESGLQLDPGPHGDCTPHSAGQRPHGP-PQSPGEEGVEAP 1416 +P P T A P P P +P + P Sbjct: 502 KSAPTTPKEPSP--TTTKEPAPTTPKEPAPTTPKKPAPTTP 540 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 43.1 bits (100), Expect = 0.002 Identities = 72/323 (22%), Positives = 113/323 (34%), Gaps = 41/323 (12%) Query: 893 ELPRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQP 952 E P P E+P AP +TP T K A ++P + E + Sbjct: 654 EEPTPTTPEEP---APTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK---ETAPT 707 Query: 953 APKGNFPSMPLVGEGDRVK--APPDAAPGLV----ASNCKSGSADSGKLAAPWHIPTIAL 1006 PKG P+ K AP + AP ++ C + + K AP T Sbjct: 708 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP---TTPKE 764 Query: 1007 PEGDIEDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVP-------SERANSPNP 1059 P +P P P+ K +TP+ P + L P S ++ P P Sbjct: 765 PAPTTPKEPAPTTPKGT---APTTLKEPAPTTPKKPAP-KELAPTTTKGPTSTTSDKPAP 820 Query: 1060 GSPGESSACSPAASNIWEESSQAPGGPELLPEEPNQAS-PWASSSPARVTRREDLTHALV 1118 +P E++ +P AP PE P ++ S P + P + + D Sbjct: 821 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPD------ 874 Query: 1119 WEGGSDPLLELSAEDLRTL---SPRGSLLDVATSPAGTSGRLELPAQLERTASKPPAVPP 1175 + ELSAE SP+ + +PA T + A+ + T P Sbjct: 875 -----ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE 929 Query: 1176 KTEKALRRAKKLASKRRKTDQAQ 1198 T A + K+ A+ KT +++ Sbjct: 930 TTTAAPKMTKETATTTEKTTESK 952 Score = 38.5 bits (88), Expect = 0.047 Identities = 69/347 (19%), Positives = 111/347 (31%), Gaps = 23/347 (6%) Query: 1025 EEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPG 1084 +E TP +TP+ P P P + E + +P AP Sbjct: 364 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 423 Query: 1085 GPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLEL-SAEDLRTLSPRGSL 1143 + P P + +P PA T +E + P + ++ +P+ Sbjct: 424 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 483 Query: 1144 LDVATSPAGTSGRLELPAQLER---TASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEK 1200 PA T+ + P + T +K P+ E A K + ++ K Sbjct: 484 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 543 Query: 1201 HGESQEGKPCPEDLEQTQQRPLCPRE----RPRHNFPVVRSLPPPV--HRHSVSGFSEPV 1254 + +P P + + P P+E P+ P P P + + +P Sbjct: 544 SAPTTPKEPSPTTTK--EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 601 Query: 1255 GRRPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPS 1314 P P TP P T K L P + E P + P T + + + P Sbjct: 602 PTTPKEPAPTTPKETAPTTPKKL-TPTTPEKLAPTTPEKPA------PTTPEELAPTTP- 653 Query: 1315 SEGASPEPPPPDALAAPYVLYPGF--QPVPVTALMPLRCSSQLSAPT 1359 E +P P A P P +P P T P + + APT Sbjct: 654 -EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 699 Score = 38.1 bits (87), Expect = 0.061 Identities = 106/545 (19%), Positives = 168/545 (30%), Gaps = 51/545 (9%) Query: 96 AATFQQLPKYVQGEEKYPKTSPPPTPVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTES 155 A T + P +E P T PTP + P + + P Sbjct: 436 APTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK--------------- 480 Query: 156 QRCESRPTASKPPALKNPPKFAPLPENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRK 215 E PTA K PA P + AP + A T + E S T P Sbjct: 481 ---EPAPTAPKKPAPTTPKEPAPTTPK------EPAPTTTK----EPSPTTPKEPAPTTT 527 Query: 216 HGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENS 275 ++K P S+ P + T + P+ +P P + T Sbjct: 528 KSAPTTTKEPAPTTTKSAPTTP-KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 586 Query: 276 AFESWNAHQPKLLERKDTAGTVPESKA---PKHYGDTTLLR-EPCPPERTVSPCQVQASC 331 +P K A T P+ A PK TT + P PE+ ++P + Sbjct: 587 T----TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK-LAPTTPEKPA 641 Query: 332 SQEENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPSSQPDSQEKPAQPPWRKPKTGKKGK 391 LA P +P ++ P++ ++PA P K K Sbjct: 642 PTTPEELAPTTPEEPTPTTPEEPAPTT------PKAAAPNTPKEPA-PTTPKEPAPTTPK 694 Query: 392 ESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISKLLTPII 451 E T +E T +G T P + A + P +P P Sbjct: 695 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKEPTSTTCDKPAPTT 753 Query: 452 PSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLKDVRKRVK 511 P K + +PA TP P + P+ + K P+ K Sbjct: 754 P-KGTAPTTPKEPAPTTPKEPAPTTP-KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPT 811 Query: 512 STYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESPP--NELSKERPADDPTASH 569 ST S P ++T + P + P E PP +E+S +PT H Sbjct: 812 STTSDKP-APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 870 Query: 570 INPQKDPTADPSEPSADSYLTLSTAPTIAKAPFYVNGEAAERSSYENKEVEGELEMGPAG 629 +P + +EP+ + P + + ++ ++K E +L P Sbjct: 871 KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPET 930 Query: 630 SSWCP 634 ++ P Sbjct: 931 TTAAP 935 Score = 38.1 bits (87), Expect = 0.061 Identities = 107/521 (20%), Positives = 157/521 (30%), Gaps = 73/521 (14%) Query: 96 AATFQQLPKYVQGEEKYPKTSPPPTPVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTES 155 A T + P +E P T P P + P + + T K T + Sbjct: 483 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 542 Query: 156 QRC-----ESRPTASKPPALKNPPKFAP-LPENSVNFCFDSAFLTVRRVPAEVSNTHQNS 209 + E PT +K PA P + AP P+ T + PA + Sbjct: 543 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT----- 597 Query: 210 YQPGRKHGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGTF 269 K + K P ++ T T E P+ KP P T Sbjct: 598 -----KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT- 651 Query: 270 LHSENSAFESWNAHQPKLLERKDTAGTVPESKAPKHYGD--TTLLREPCP-PERTVSPCQ 326 +P ++ A T P++ AP + T +EP P + +P Sbjct: 652 -----------TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 700 Query: 327 VQASCSQEENRLAAGALSTSIPWGCRDPGAQVFA-VEGKAPSSQPDSQEKPAQPPWRKPK 385 + + A L P + P + A K P+S + P P P Sbjct: 701 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT 760 Query: 386 TGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISK 445 T KE T +E T +G T P + A + P P S Sbjct: 761 T---PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSD 816 Query: 446 LLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLKD 505 P P K + +PA TP P + P+ + +K P+ + Sbjct: 817 KPAPTTP-KETAPTTPKEPAPTTPKKPAPTTP-ETPPPTTSEVSTPTTTKEPTTIH---- 870 Query: 506 VRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESP--PNELSKERPAD 563 KS S+P L EP P LE SP P + + PA Sbjct: 871 -----KSPDESTPELSA-------------EPT------PKALENSPKEPGVPTTKTPAA 906 Query: 564 -----DPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAK 599 TA ++D P +A +T TA T K Sbjct: 907 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK 947 Score = 38.1 bits (87), Expect = 0.061 Identities = 87/425 (20%), Positives = 134/425 (31%), Gaps = 53/425 (12%) Query: 895 PRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAP 954 P P ++P P+ T + T P + S E + P Sbjct: 506 PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 565 Query: 955 KGNFPSMPLVGEGDRVKAPPDAAPGLVA-SNCKSGSADSGKLAAPWH----IPTI----- 1004 K P+ P K P P A + K + + K AP PT Sbjct: 566 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 625 Query: 1005 -ALPEG---DIEDQPPPWQPENCW----EEQTPGFKSHFL-STPRAGPPGRRLVPSERA- 1054 PE ++P P PE EE TP +TP+A P P+ Sbjct: 626 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 685 Query: 1055 --------NSPNPGSPGESSACSP---AASNIWEESSQAPGGP---ELLPEEPNQASPWA 1100 P P +P E++ +P A + + E + P P EL P + + Sbjct: 686 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 745 Query: 1101 SSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELP 1160 PA T + +P E T +P+G+ PA T+ + P Sbjct: 746 CDKPAPTTPKGTAPTT-----PKEPAPTTPKEPAPT-TPKGTAPTTLKEPAPTTPKKPAP 799 Query: 1161 AQLERTASKPPAVPPKTEKALRRAKKLA--SKRRKTDQAQEKHGESQEGKPCPEDLE--- 1215 +L T +K P + A K+ A + + +K + P P E Sbjct: 800 KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 859 Query: 1216 -QTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPAYPATQ 1274 T + P + P + P + + P P E + PG P + TP P Sbjct: 860 PTTTKEPTTIHKSPDESTPELSAEPTP-------KALENSPKEPGVPTTKTPAATKPEMT 912 Query: 1275 KVLQD 1279 +D Sbjct: 913 TTAKD 917 Score = 37.4 bits (85), Expect = 0.10 Identities = 48/210 (22%), Positives = 71/210 (33%), Gaps = 15/210 (7%) Query: 401 KTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHALDSA 460 K +T +GP L T P + A P EP P S TP P+ SA Sbjct: 334 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT----PTTIKSAPTTPKEPAPTTTKSA 389 Query: 461 DSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLKD----VRKRVKSTYSS 516 + P E P+ + KEP+ +++ + S K+ K+ T Sbjct: 390 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 449 Query: 517 SPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESPPNELSKERPADDPTASHINPQKD- 575 P E T K+ + P +E P K P + P++ Sbjct: 450 EPAPTTPKEPT--PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 507 Query: 576 PTA----DPSEPSADSYLTLSTAPTIAKAP 601 PT P+ P + T +APT K P Sbjct: 508 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 537 Score = 35.0 bits (79), Expect = 0.52 Identities = 64/281 (22%), Positives = 86/281 (30%), Gaps = 36/281 (12%) Query: 1151 AGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQE-KHGESQEGKP 1209 A TS L P T +K PA+ E K+ AS K K + +P Sbjct: 322 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 381 Query: 1210 CPEDLEQTQQRPLCPRE------------RPRHNFPVVRSLPPPVHRHSVSGF-SEPVGR 1256 P T+ P P+E P+ P P P S EP Sbjct: 382 APTT---TKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 438 Query: 1257 RPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPSSE 1316 P P TP P T K +P P K P T + + Sbjct: 439 TPKKPAPTTPKEPAPTTPK---EPT---------PTTPKEPA---PTTKEPAPTTPKEPA 483 Query: 1317 GASPEPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASAARARTQS 1376 +P+ P P P P +P P T P + + APT + P + A T + Sbjct: 484 PTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 542 Query: 1377 VHESGLQLDPGPHGDCTPHSAGQRPHGP-PQSPGEEGVEAP 1416 +P P T A P P P +P + P Sbjct: 543 KSAPTTPKEPSP--TTTKEPAPTTPKEPAPTTPKKPAPTTP 581 >gi|148806908 fibronectin type III domain containing 1 [Homo sapiens] Length = 1894 Score = 43.1 bits (100), Expect = 0.002 Identities = 66/277 (23%), Positives = 96/277 (34%), Gaps = 32/277 (11%) Query: 1146 VATSPAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQ 1205 V SP G + + +L L+ P K + ++A++L + T+ E+ S+ Sbjct: 493 VPASPQGRNAK-DLLLDLKNKILANGGAPRKPQLRAKKAEEL--DLQSTEITGEEELGSR 549 Query: 1206 EGKPCPEDLEQTQQRPLCPRERPRHNF-----PVVRSLPPPVHRHS---VSGFSEPVGRR 1257 E P Q Q+R L P R H+ VR+ P + R GFS R Sbjct: 550 EDSPMSPSDTQDQKRTLRPPSRHGHSVVAPGRTAVRARMPALPRREGVDKPGFSLATQPR 609 Query: 1258 PGGPQSLTPLPAYPA-TQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSI-PSS 1315 PG P S + PA+ A TQ P LP + D + + S+ P Sbjct: 610 PGAPPSASASPAHHASTQGTSHRP--------SLPASLNDNDLVDSDEDERAVGSLHPKG 661 Query: 1316 EGASPEP-------PPPDALAAPYVLYPGFQPVPVTALMP----LRCSSQLSAPTFLRQG 1364 A P P P L ++PG +P P S SAP Sbjct: 662 AFAQPRPALSPSRQSPSSVLRDRSSVHPGAKPASPARRTPHSGAAEEDSSASAPPSRLSP 721 Query: 1365 PRASAARARTQSVHESGLQLDPGPHGDCTPHSAGQRP 1401 P ++R H S G G+ P + P Sbjct: 722 PHGGSSRLLPTQPHLSSPLSKGGKDGEDAPATNSNAP 758 Score = 31.2 bits (69), Expect = 7.5 Identities = 78/399 (19%), Positives = 135/399 (33%), Gaps = 73/399 (18%) Query: 888 GHKEEELPRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARM 947 G +E+E P P N + +S +RG ++ P +G+S+ R Sbjct: 877 GDEEDEKPLP--------ATVVNDHVPSSSRQPISRGWE------DLRRSPQRGASLHRK 922 Query: 948 E---------ASQPAPKGNFPSMPLVGE-------GDRVKAPPDAAPGLVASNCKSGSAD 991 E + P+G + S+ + D P A PG + Sbjct: 923 EPIPENPKSTGADTHPQGKYSSLASKAQDVQQSTDADTEGHSPKAQPGSTDRHASPARPP 982 Query: 992 SGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFKSHF---------LSTPRAG 1042 + + +P P + QPPP + PG +S LS +AG Sbjct: 983 AARSQQHPSVPRRMTPGRAPQQQPPP---PVATSQHHPGPQSRDAGRSPSQPRLSLTQAG 1039 Query: 1043 PPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPGGPELLPEEPNQASPWASS 1102 P P+ + S + P +S+ + + + A G + ++ + Sbjct: 1040 RPR----PTSQGRSHSSSDPYTASSRGMLPTALQNQDEDAQGSYD---DDSTEVEAQDVR 1092 Query: 1103 SPARVTRREDLTHALV-WEGGSDPLLELSAEDLRTLSPRGSLLDVA--TSPAGTSGRLEL 1159 +PA R ++ +L + P + D R S RG A + P G R + Sbjct: 1093 APAHAARAKEAAASLPKHQQVESPTGAGAGGDHR--SQRGHAASPARPSRPGGPQSRARV 1150 Query: 1160 PAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGES--------------- 1204 P++ S+PP+ P + K+ + A + D K G+ Sbjct: 1151 PSRAAPGKSEPPSKRPLSSKSQQSVS--AEDDEEEDAGFFKGGKEDLLSSSVPKWPSSST 1208 Query: 1205 -QEGKPCPEDLEQTQQRP-LCPRERPRHNFPVVRSLPPP 1241 + GK L + ++ P + R PV R LPPP Sbjct: 1209 PRGGKDADGSLAKEEREPAIALAPRGGSLAPVKRPLPPP 1247 >gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sapiens] Length = 2715 Score = 43.1 bits (100), Expect = 0.002 Identities = 90/436 (20%), Positives = 137/436 (31%), Gaps = 65/436 (14%) Query: 1025 EEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPG 1084 EE P + P PP PS P P + C P + +P Sbjct: 388 EEMMPAAEKEEAKLPP--PPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPP 445 Query: 1085 GPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLL 1144 P E+ P ++ +R R LT + + + + P G+ Sbjct: 446 PPPAQEEQEESPPPVVPATCSRKRGRPPLTPS-----------QRAEREAARAGPEGTSP 494 Query: 1145 DVATSPAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKK-----LASKRRKTDQAQE 1199 T T G E P V PK+ L+ ++ ++++ + + Sbjct: 495 PTPTPSTATGGPPE----------DSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPR 544 Query: 1200 KHGESQEGKPCPEDLEQTQQRPL-----CPRE------RPRHNFPVVRSLPPPVHRHSVS 1248 + + KP ++ + P+ P+E PR P +P P R S+ Sbjct: 545 RFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSI- 603 Query: 1249 GFSEPVGRRPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGK-- 1306 EP R + L P P P P PL ++ F E Sbjct: 604 -LREPTFRWTSLTRELPPPPPAPPPPPA-PSPPPAPATSSRRPLLLRAPQFTPSEAHLKI 661 Query: 1307 YVKVSIPSSEGA--SPEPPPPDALAAP------------YVLYPGFQPVPVTALMPLRCS 1352 Y V P GA +PEP PP A +P ++ P F PV T P++ Sbjct: 662 YESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTT---PVKAE 718 Query: 1353 SQLSAPTFLRQGPRASAARARTQSVHESGLQLDPGPHGDCTPHSAGQRPHGPPQSPGEEG 1412 L GP+ A + LQ P P Q P P Q P E Sbjct: 719 VSPHGAPALSNGPQTQAQLLQPL----QALQTQLLPQALPPPQPQLQPPPSPQQMPPLEK 774 Query: 1413 VEAPGLGIISTDDLED 1428 G+G + +E+ Sbjct: 775 ARIAGVGSLPLSGVEE 790 Score = 32.7 bits (73), Expect = 2.6 Identities = 38/162 (23%), Positives = 61/162 (37%), Gaps = 3/162 (1%) Query: 1190 KRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSG 1249 + +K ++ ++K GE +E + E++ ++ P P S PPP+ S S Sbjct: 366 EEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLT-PPAPSPPPPLPPPSTSP 424 Query: 1250 FSEPVGRRPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVK 1309 P+ P P S PLP+ P + +S V + + + P + Sbjct: 425 -PPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAERE 483 Query: 1310 VSIPSSEGASPEPPPPD-ALAAPYVLYPGFQPVPVTALMPLR 1350 + EG SP P P A P P P T L +R Sbjct: 484 AARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIR 525 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.309 0.128 0.381 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 72,614,078 Number of Sequences: 37866 Number of extensions: 4372340 Number of successful extensions: 20307 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 37 Number of HSP's successfully gapped in prelim test: 670 Number of HSP's that attempted gapping in prelim test: 17111 Number of HSP's gapped (non-prelim): 3925 length of query: 1435 length of database: 18,247,518 effective HSP length: 115 effective length of query: 1320 effective length of database: 13,892,928 effective search space: 18338664960 effective search space used: 18338664960 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.