Guide to the Human Genome
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Search of human proteins with 206597543

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|206597543 hypothetical protein LOC118461 isoform 1 [Homo
sapiens]
         (1435 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|206597543 hypothetical protein LOC118461 isoform 1 [Homo sapi...  2944   0.0  
gi|49574498 hypothetical protein LOC118461 isoform 2 [Homo sapiens]  1424   0.0  
gi|238908524 hypothetical protein LOC389333 [Homo sapiens]             84   1e-15
gi|169167062 PREDICTED: hypothetical protein LOC285556 [Homo sap...    71   7e-12
gi|113416182 PREDICTED: hypothetical protein LOC285556 [Homo sap...    71   7e-12
gi|113415686 PREDICTED: hypothetical protein LOC285556 [Homo sap...    71   7e-12
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     56   2e-07
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ...    55   6e-07
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         54   1e-06
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e...    53   2e-06
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d...    53   2e-06
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ...    53   2e-06
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ...    53   2e-06
gi|238624188 diffuse panbronchiolitis critical region 1 protein ...    53   2e-06
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    51   7e-06
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit...    50   1e-05
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        50   1e-05
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    47   2e-04
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]         46   2e-04
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f...    45   4e-04
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ...    45   4e-04
gi|163965366 nascent polypeptide-associated complex alpha subuni...    45   5e-04
gi|33667044 ABI gene family, member 3 (NESH) binding protein [Ho...    44   0.001
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  44   0.001
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   43   0.002
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   43   0.002
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   43   0.002
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    43   0.002
gi|148806908 fibronectin type III domain containing 1 [Homo sapi...    43   0.002
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    43   0.002

>gi|206597543 hypothetical protein LOC118461 isoform 1 [Homo sapiens]
          Length = 1435

 Score = 2944 bits (7633), Expect = 0.0
 Identities = 1435/1435 (100%), Positives = 1435/1435 (100%)

Query: 1    MMQGNKKCTDAFSDSSSIGSVLDDADREVSSLTDRAFRSLCISEDTSFHDSYLAVSPDIT 60
            MMQGNKKCTDAFSDSSSIGSVLDDADREVSSLTDRAFRSLCISEDTSFHDSYLAVSPDIT
Sbjct: 1    MMQGNKKCTDAFSDSSSIGSVLDDADREVSSLTDRAFRSLCISEDTSFHDSYLAVSPDIT 60

Query: 61   RQVFGTFHQRTVGHTQRKSGIWSQLPSQGTEHSGWAATFQQLPKYVQGEEKYPKTSPPPT 120
            RQVFGTFHQRTVGHTQRKSGIWSQLPSQGTEHSGWAATFQQLPKYVQGEEKYPKTSPPPT
Sbjct: 61   RQVFGTFHQRTVGHTQRKSGIWSQLPSQGTEHSGWAATFQQLPKYVQGEEKYPKTSPPPT 120

Query: 121  PVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTESQRCESRPTASKPPALKNPPKFAPLP 180
            PVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTESQRCESRPTASKPPALKNPPKFAPLP
Sbjct: 121  PVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTESQRCESRPTASKPPALKNPPKFAPLP 180

Query: 181  ENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQESSKNPEMACHGSSSFLPAAN 240
            ENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQESSKNPEMACHGSSSFLPAAN
Sbjct: 181  ENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQESSKNPEMACHGSSSFLPAAN 240

Query: 241  DTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENSAFESWNAHQPKLLERKDTAGTVPES 300
            DTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENSAFESWNAHQPKLLERKDTAGTVPES
Sbjct: 241  DTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENSAFESWNAHQPKLLERKDTAGTVPES 300

Query: 301  KAPKHYGDTTLLREPCPPERTVSPCQVQASCSQEENRLAAGALSTSIPWGCRDPGAQVFA 360
            KAPKHYGDTTLLREPCPPERTVSPCQVQASCSQEENRLAAGALSTSIPWGCRDPGAQVFA
Sbjct: 301  KAPKHYGDTTLLREPCPPERTVSPCQVQASCSQEENRLAAGALSTSIPWGCRDPGAQVFA 360

Query: 361  VEGKAPSSQPDSQEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQ 420
            VEGKAPSSQPDSQEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQ
Sbjct: 361  VEGKAPSSQPDSQEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQ 420

Query: 421  FSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQE 480
            FSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQE
Sbjct: 421  FSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQE 480

Query: 481  KEPSECQSRDSYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSN 540
            KEPSECQSRDSYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSN
Sbjct: 481  KEPSECQSRDSYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSN 540

Query: 541  GVILPNGLEESPPNELSKERPADDPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAKA 600
            GVILPNGLEESPPNELSKERPADDPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAKA
Sbjct: 541  GVILPNGLEESPPNELSKERPADDPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAKA 600

Query: 601  PFYVNGEAAERSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPGGAT 660
            PFYVNGEAAERSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPGGAT
Sbjct: 601  PFYVNGEAAERSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPGGAT 660

Query: 661  EKMKTHQLENGLSRSVSQETEPEREAGLQNTHLNQKFFPGPLSPEEEDVFYSDSQSDFMP 720
            EKMKTHQLENGLSRSVSQETEPEREAGLQNTHLNQKFFPGPLSPEEEDVFYSDSQSDFMP
Sbjct: 661  EKMKTHQLENGLSRSVSQETEPEREAGLQNTHLNQKFFPGPLSPEEEDVFYSDSQSDFMP 720

Query: 721  SLKGKAKFSTSSSDQSFASFDDQQKMWFTENQREDRRKDVSAGDSQKDEKENVMRKDELQ 780
            SLKGKAKFSTSSSDQSFASFDDQQKMWFTENQREDRRKDVSAGDSQKDEKENVMRKDELQ
Sbjct: 721  SLKGKAKFSTSSSDQSFASFDDQQKMWFTENQREDRRKDVSAGDSQKDEKENVMRKDELQ 780

Query: 781  YCALSNGHACLENRSQGEALQRERESVSGGRTRKASAEEANFRGSWIGENKGTTFSQAKD 840
            YCALSNGHACLENRSQGEALQRERESVSGGRTRKASAEEANFRGSWIGENKGTTFSQAKD
Sbjct: 781  YCALSNGHACLENRSQGEALQRERESVSGGRTRKASAEEANFRGSWIGENKGTTFSQAKD 840

Query: 841  LTPSPSSASNRHMLFTIKDNTLRATPVIKPIMLPLLRTMSLEDSLSSGHKEEELPRPEWG 900
            LTPSPSSASNRHMLFTIKDNTLRATPVIKPIMLPLLRTMSLEDSLSSGHKEEELPRPEWG
Sbjct: 841  LTPSPSSASNRHMLFTIKDNTLRATPVIKPIMLPLLRTMSLEDSLSSGHKEEELPRPEWG 900

Query: 901  EDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAPKGNFPS 960
            EDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAPKGNFPS
Sbjct: 901  EDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAPKGNFPS 960

Query: 961  MPLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIPTIALPEGDIEDQPPPWQP 1020
            MPLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIPTIALPEGDIEDQPPPWQP
Sbjct: 961  MPLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIPTIALPEGDIEDQPPPWQP 1020

Query: 1021 ENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESS 1080
            ENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESS
Sbjct: 1021 ENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESS 1080

Query: 1081 QAPGGPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPR 1140
            QAPGGPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPR
Sbjct: 1081 QAPGGPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPR 1140

Query: 1141 GSLLDVATSPAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEK 1200
            GSLLDVATSPAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEK
Sbjct: 1141 GSLLDVATSPAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEK 1200

Query: 1201 HGESQEGKPCPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGG 1260
            HGESQEGKPCPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGG
Sbjct: 1201 HGESQEGKPCPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGG 1260

Query: 1261 PQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPSSEGASP 1320
            PQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPSSEGASP
Sbjct: 1261 PQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPSSEGASP 1320

Query: 1321 EPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASAARARTQSVHES 1380
            EPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASAARARTQSVHES
Sbjct: 1321 EPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASAARARTQSVHES 1380

Query: 1381 GLQLDPGPHGDCTPHSAGQRPHGPPQSPGEEGVEAPGLGIISTDDLEDFATEGIS 1435
            GLQLDPGPHGDCTPHSAGQRPHGPPQSPGEEGVEAPGLGIISTDDLEDFATEGIS
Sbjct: 1381 GLQLDPGPHGDCTPHSAGQRPHGPPQSPGEEGVEAPGLGIISTDDLEDFATEGIS 1435


>gi|49574498 hypothetical protein LOC118461 isoform 2 [Homo sapiens]
          Length = 719

 Score = 1424 bits (3685), Expect = 0.0
 Identities = 692/692 (100%), Positives = 692/692 (100%)

Query: 1   MMQGNKKCTDAFSDSSSIGSVLDDADREVSSLTDRAFRSLCISEDTSFHDSYLAVSPDIT 60
           MMQGNKKCTDAFSDSSSIGSVLDDADREVSSLTDRAFRSLCISEDTSFHDSYLAVSPDIT
Sbjct: 1   MMQGNKKCTDAFSDSSSIGSVLDDADREVSSLTDRAFRSLCISEDTSFHDSYLAVSPDIT 60

Query: 61  RQVFGTFHQRTVGHTQRKSGIWSQLPSQGTEHSGWAATFQQLPKYVQGEEKYPKTSPPPT 120
           RQVFGTFHQRTVGHTQRKSGIWSQLPSQGTEHSGWAATFQQLPKYVQGEEKYPKTSPPPT
Sbjct: 61  RQVFGTFHQRTVGHTQRKSGIWSQLPSQGTEHSGWAATFQQLPKYVQGEEKYPKTSPPPT 120

Query: 121 PVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTESQRCESRPTASKPPALKNPPKFAPLP 180
           PVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTESQRCESRPTASKPPALKNPPKFAPLP
Sbjct: 121 PVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTESQRCESRPTASKPPALKNPPKFAPLP 180

Query: 181 ENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQESSKNPEMACHGSSSFLPAAN 240
           ENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQESSKNPEMACHGSSSFLPAAN
Sbjct: 181 ENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQESSKNPEMACHGSSSFLPAAN 240

Query: 241 DTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENSAFESWNAHQPKLLERKDTAGTVPES 300
           DTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENSAFESWNAHQPKLLERKDTAGTVPES
Sbjct: 241 DTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENSAFESWNAHQPKLLERKDTAGTVPES 300

Query: 301 KAPKHYGDTTLLREPCPPERTVSPCQVQASCSQEENRLAAGALSTSIPWGCRDPGAQVFA 360
           KAPKHYGDTTLLREPCPPERTVSPCQVQASCSQEENRLAAGALSTSIPWGCRDPGAQVFA
Sbjct: 301 KAPKHYGDTTLLREPCPPERTVSPCQVQASCSQEENRLAAGALSTSIPWGCRDPGAQVFA 360

Query: 361 VEGKAPSSQPDSQEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQ 420
           VEGKAPSSQPDSQEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQ
Sbjct: 361 VEGKAPSSQPDSQEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQ 420

Query: 421 FSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQE 480
           FSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQE
Sbjct: 421 FSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQE 480

Query: 481 KEPSECQSRDSYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSN 540
           KEPSECQSRDSYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSN
Sbjct: 481 KEPSECQSRDSYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSN 540

Query: 541 GVILPNGLEESPPNELSKERPADDPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAKA 600
           GVILPNGLEESPPNELSKERPADDPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAKA
Sbjct: 541 GVILPNGLEESPPNELSKERPADDPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAKA 600

Query: 601 PFYVNGEAAERSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPGGAT 660
           PFYVNGEAAERSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPGGAT
Sbjct: 601 PFYVNGEAAERSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPGGAT 660

Query: 661 EKMKTHQLENGLSRSVSQETEPEREAGLQNTH 692
           EKMKTHQLENGLSRSVSQETEPEREAGLQNTH
Sbjct: 661 EKMKTHQLENGLSRSVSQETEPEREAGLQNTH 692


>gi|238908524 hypothetical protein LOC389333 [Homo sapiens]
          Length = 1015

 Score = 83.6 bits (205), Expect = 1e-15
 Identities = 115/463 (24%), Positives = 166/463 (35%), Gaps = 71/463 (15%)

Query: 917  STPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAPKGNFPSMPLVGEGDRVKAPPDA 976
            S P     T ++  +   + D   G S    E + P P G+ P    VG  D  K P   
Sbjct: 552  SAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHP----VGTLDADKCPEVL 607

Query: 977  APGLVASNCKSGSA----DSGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFK 1032
             PG  AS     +     D  KL    + P    P G      P    + C EE   G +
Sbjct: 608  GPGEAASGRPRMAIPRPRDVRKLVKTTYAP--GFPAGAQGSGLPAPPADPCGEE---GGE 662

Query: 1033 SHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPGGPELLPEE 1092
            S     P  GPP      S       P  P       P+   +  ++SQ P G      E
Sbjct: 663  SKTQEPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQ-PNGVLRRRAE 721

Query: 1093 PNQASPWASSS-----PARVTRREDLTHALVWEGGSDPLLELSAEDL------RTLSPRG 1141
             + A P+  +         + RR ++T  +   G      ++ A+ L      RT    G
Sbjct: 722  NSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGG 781

Query: 1142 SLLDVATSPAGTSG-RLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEK 1200
            +      SP G +G R   P   +  AS  P + PK +      +  A+ +         
Sbjct: 782  ARSSSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQA-------- 833

Query: 1201 HGESQEGKPCPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGG 1260
                    P P +       PL    R     P   S PP     S    S+   R+PG 
Sbjct: 834  --------PLPRE-------PLALAGRTAPAQPRAASAPPT--DRSPQSPSQGARRQPGA 876

Query: 1261 PQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPSSEGASP 1320
                 PL       KVL DP+SG Y+  + P Q +++  +DPE+G+YV+V +P S     
Sbjct: 877  ----APLG------KVLVDPESGRYYFVEAPRQPRLRVLFDPESGQYVEVLLPPS----- 921

Query: 1321 EPPPPDALAAPYVL-----YPGFQPVPVTALMPLRCSSQLSAP 1358
             P PP  +  P  L      P + P+P  +L P      L +P
Sbjct: 922  SPGPPHRVYTPLALGLGLYPPAYGPIPSLSLPPSPGPQALGSP 964



 Score = 33.1 bits (74), Expect = 2.0
 Identities = 39/158 (24%), Positives = 57/158 (36%), Gaps = 34/158 (21%)

Query: 959  PSMPLVGEGDRV----KAPPDAAPGL-------VASNCKSGSADSGKLAAPWHIPTIALP 1007
            PS P++ + ++     ++P   AP L       VA   +  S+ S     PW  P     
Sbjct: 453  PSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEPRSSPSPPAFFPWEAP----- 507

Query: 1008 EGDIEDQP-PPW--QPENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGE 1064
                 D+P   W   P+  W+   PG    F    + G     L P      P P +PG 
Sbjct: 508  -----DRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELAP------PTPSAPGT 556

Query: 1065 SSACSPAASNIWEESSQAPGG----PELLPEEPNQASP 1098
                   + +  E S  A GG    PE+   EP  + P
Sbjct: 557  PEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHP 594


>gi|169167062 PREDICTED: hypothetical protein LOC285556 [Homo sapiens]
          Length = 1826

 Score = 71.2 bits (173), Expect = 7e-12
 Identities = 92/346 (26%), Positives = 139/346 (40%), Gaps = 64/346 (18%)

Query: 1043 PPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQA---PGGPELLPEEPNQASPW 1099
            PP  + V   +   P P  P   +  + +AS+I +    A   P GP   PE P+ A   
Sbjct: 1406 PPVHKDVERTQPLQPLPPLPSNRNVFTVSASSIQKTGGVAGKFPQGPS--PESPSAAKGI 1463

Query: 1100 ASS-------SPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAG 1152
             S        SPA     +++T+    + GS+  LE S  D        + L +    + 
Sbjct: 1464 KSQGLRSLKISPATRAPPDEVTNR---KSGSN--LEKSNSDCE------NYLTIPLKGSS 1512

Query: 1153 TSGRLELPAQLERTASKPPAV---PPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKP 1209
             +G L          S+P A    PP +  A   +    S R +   + +    S   +P
Sbjct: 1513 AAGEL---------LSRPGASREGPPNSSAATLCSLPPLSARSQVPSSSKGSQVSGTSRP 1563

Query: 1210 C----PEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVH-----RHSVSGFSEPVGRRPGG 1260
                 P++  +T   P  P+  P H    +   PP        +  V  FS P    P  
Sbjct: 1564 AWRTKPDNPRETVAAPPGPQS-PEHPPTTIYHQPPLPFTLQGAQPQVLCFSPPSMPAPA- 1621

Query: 1261 PQSLTPLPAYPATQ--------KVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSI 1312
            P +  P+P  P  Q        K+L D  +G+Y++ D P+Q   +  +DPETG+YV V +
Sbjct: 1622 PAASAPVPTDPFQQAQPQQTQRKMLLDVTTGQYYLVDTPVQPMTRRLFDPETGQYVDVPM 1681

Query: 1313 PSSEGA----SPEPPP----PDALAAPYVLYPGFQP--VPVTALMP 1348
             S + A    S   PP    P A    Y++YPGF P  +P  AL P
Sbjct: 1682 TSQQQAVAPMSISVPPLALSPGAYGPTYMIYPGFLPTVLPTNALQP 1727



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 125/579 (21%), Positives = 203/579 (35%), Gaps = 108/579 (18%)

Query: 6    KKCTDAFSDSSSIGSVLDDADREVSSLTDRAFRSLCISEDTSFHDSYLAVSPDITRQVFG 65
            K+  D  S +SS  S LDDAD+EV +LT RAFRSL      + + S    S  ++   FG
Sbjct: 633  KELVDYSSGASSAVSELDDADKEVRNLTSRAFRSLAYPYFEALNISSRESSTTLSEVGFG 692

Query: 66   TFHQ------RTVGHTQRKSGIWSQLPSQGT---EHSGWAATFQQLPKYVQGEEKYPKTS 116
             +          VG    +S + S   S      + SG  AT  QL  Y+Q ++   K  
Sbjct: 693  RWSTFLDLKCGGVGARVEQSLLRSSAASVAAGLRKGSGARATADQL--YIQSKKSQTKA- 749

Query: 117  PPPTPVQRRLEVPVSGLRSSNKPV-------------SKVSTLIKSFDRTESQRCESRPT 163
                     LE  VS +    K V             S+V TL++  +     +  S P 
Sbjct: 750  ---------LEFVVSKVEGEIKHVETPLCFQKQVQTGSRVVTLLEPLNVRSESKASSAPG 800

Query: 164  ASKPPALKNPPKFAPLPENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQESSK 223
              +  A K P K              SA+        + S T + S    R  G Q+S  
Sbjct: 801  PGR--ATKGPGKGP-----------GSAYTD------DGSETSEGSKPTSRADGPQKSKF 841

Query: 224  NPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRG-KGTFLHSENSAFESWNA 282
               +  +  S  +   ++          + HH   T +   G +G+    E       + 
Sbjct: 842  ASSLLKNVISKKMQREHEFKMERGEVMDTSHHLSGTSKETEGARGSERQRERGLQRQSSR 901

Query: 283  H-----QPKLLERKDTA--GTVPESKAPKHYGDTTLLREPCP----PERTVSPCQVQASC 331
            H     +  ++   D    G+V  SK+P     T   R   P     +     C+++ S 
Sbjct: 902  HSEAGSEYTVVSMSDAGGEGSVAGSKSPVFKASTPRERNAGPGRNFTDGHTEVCEIKKSA 961

Query: 332  SQEENRLAAGALSTSI-PWGCRDPGAQVFAVEGKAPSSQPDSQEKPAQPPWRKPKTGKKG 390
            S+    +   + +++   W                   + +++++  Q P  K K  K G
Sbjct: 962  SETVKGIFLRSQNSAFRSW------------------KEKEAEKREEQAPIGKLKLPKGG 1003

Query: 391  --KESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLP---------VEPN----- 434
              +  L +    K     R      +  P+++     A   P         + P      
Sbjct: 1004 DWRADLGEISASKNTIMSRLFVPNIQQTPKDKQPRKQATKYPAAQATSTAVIRPKAPEIK 1063

Query: 435  ------EHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQS 488
                  +     FNI+KLLTP +    A  +      + + +      G   ++    Q 
Sbjct: 1064 IRLGSVQQPSSDFNIAKLLTPKLAGGSA-SNLFKTIEDNSRAQQKLFRGDNLEKVPHFQV 1122

Query: 489  RD-SYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEK 526
            RD   KSKA   L  ++DVRK +K +  SS    V  E+
Sbjct: 1123 RDIRDKSKAQGPLHQVRDVRKLIKGSGDSSDKGSVTPEQ 1161


>gi|113416182 PREDICTED: hypothetical protein LOC285556 [Homo sapiens]
          Length = 1826

 Score = 71.2 bits (173), Expect = 7e-12
 Identities = 92/346 (26%), Positives = 139/346 (40%), Gaps = 64/346 (18%)

Query: 1043 PPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQA---PGGPELLPEEPNQASPW 1099
            PP  + V   +   P P  P   +  + +AS+I +    A   P GP   PE P+ A   
Sbjct: 1406 PPVHKDVERTQPLQPLPPLPSNRNVFTVSASSIQKTGGVAGKFPQGPS--PESPSAAKGI 1463

Query: 1100 ASS-------SPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAG 1152
             S        SPA     +++T+    + GS+  LE S  D        + L +    + 
Sbjct: 1464 KSQGLRSLKISPATRAPPDEVTNR---KSGSN--LEKSNSDCE------NYLTIPLKGSS 1512

Query: 1153 TSGRLELPAQLERTASKPPAV---PPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKP 1209
             +G L          S+P A    PP +  A   +    S R +   + +    S   +P
Sbjct: 1513 AAGEL---------LSRPGASREGPPNSSAATLCSLPPLSARSQVPSSSKGSQVSGTSRP 1563

Query: 1210 C----PEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVH-----RHSVSGFSEPVGRRPGG 1260
                 P++  +T   P  P+  P H    +   PP        +  V  FS P    P  
Sbjct: 1564 AWRTKPDNPRETVAAPPGPQS-PEHPPTTIYHQPPLPFTLQGAQPQVLCFSPPSMPAPA- 1621

Query: 1261 PQSLTPLPAYPATQ--------KVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSI 1312
            P +  P+P  P  Q        K+L D  +G+Y++ D P+Q   +  +DPETG+YV V +
Sbjct: 1622 PAASAPVPTDPFQQAQPQQTQRKMLLDVTTGQYYLVDTPVQPMTRRLFDPETGQYVDVPM 1681

Query: 1313 PSSEGA----SPEPPP----PDALAAPYVLYPGFQP--VPVTALMP 1348
             S + A    S   PP    P A    Y++YPGF P  +P  AL P
Sbjct: 1682 TSQQQAVAPMSISVPPLALSPGAYGPTYMIYPGFLPTVLPTNALQP 1727



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 125/579 (21%), Positives = 203/579 (35%), Gaps = 108/579 (18%)

Query: 6    KKCTDAFSDSSSIGSVLDDADREVSSLTDRAFRSLCISEDTSFHDSYLAVSPDITRQVFG 65
            K+  D  S +SS  S LDDAD+EV +LT RAFRSL      + + S    S  ++   FG
Sbjct: 633  KELVDYSSGASSAVSELDDADKEVRNLTSRAFRSLAYPYFEALNISSRESSTTLSEVGFG 692

Query: 66   TFHQ------RTVGHTQRKSGIWSQLPSQGT---EHSGWAATFQQLPKYVQGEEKYPKTS 116
             +          VG    +S + S   S      + SG  AT  QL  Y+Q ++   K  
Sbjct: 693  RWSTFLDLKCGGVGARVEQSLLRSSAASVAAGLRKGSGARATADQL--YIQSKKSQTKA- 749

Query: 117  PPPTPVQRRLEVPVSGLRSSNKPV-------------SKVSTLIKSFDRTESQRCESRPT 163
                     LE  VS +    K V             S+V TL++  +     +  S P 
Sbjct: 750  ---------LEFVVSKVEGEIKHVETPLCFQKQVQTGSRVVTLLEPLNVRSESKASSAPG 800

Query: 164  ASKPPALKNPPKFAPLPENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQESSK 223
              +  A K P K              SA+        + S T + S    R  G Q+S  
Sbjct: 801  PGR--ATKGPGKGP-----------GSAYTD------DGSETSEGSKPTSRADGPQKSKF 841

Query: 224  NPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRG-KGTFLHSENSAFESWNA 282
               +  +  S  +   ++          + HH   T +   G +G+    E       + 
Sbjct: 842  ASSLLKNVISKKMQREHEFKMERGEVMDTSHHLSGTSKETEGARGSERQRERGLQRQSSR 901

Query: 283  H-----QPKLLERKDTA--GTVPESKAPKHYGDTTLLREPCP----PERTVSPCQVQASC 331
            H     +  ++   D    G+V  SK+P     T   R   P     +     C+++ S 
Sbjct: 902  HSEAGSEYTVVSMSDAGGEGSVAGSKSPVFKASTPRERNAGPGRNFTDGHTEVCEIKKSA 961

Query: 332  SQEENRLAAGALSTSI-PWGCRDPGAQVFAVEGKAPSSQPDSQEKPAQPPWRKPKTGKKG 390
            S+    +   + +++   W                   + +++++  Q P  K K  K G
Sbjct: 962  SETVKGIFLRSQNSAFRSW------------------KEKEAEKREEQAPIGKLKLPKGG 1003

Query: 391  --KESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLP---------VEPN----- 434
              +  L +    K     R      +  P+++     A   P         + P      
Sbjct: 1004 DWRADLGEISASKNTIMSRLFVPNIQQTPKDKQPRKQATKYPAAQATSTAVIRPKAPEIK 1063

Query: 435  ------EHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQS 488
                  +     FNI+KLLTP +    A  +      + + +      G   ++    Q 
Sbjct: 1064 IRLGSVQQPSSDFNIAKLLTPKLAGGSA-SNLFKTIEDNSRAQQKLFRGDNLEKVPHFQV 1122

Query: 489  RD-SYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEK 526
            RD   KSKA   L  ++DVRK +K +  SS    V  E+
Sbjct: 1123 RDIRDKSKAQGPLHQVRDVRKLIKGSGDSSDKGSVTPEQ 1161


>gi|113415686 PREDICTED: hypothetical protein LOC285556 [Homo sapiens]
          Length = 1826

 Score = 71.2 bits (173), Expect = 7e-12
 Identities = 92/346 (26%), Positives = 139/346 (40%), Gaps = 64/346 (18%)

Query: 1043 PPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQA---PGGPELLPEEPNQASPW 1099
            PP  + V   +   P P  P   +  + +AS+I +    A   P GP   PE P+ A   
Sbjct: 1406 PPVHKDVERTQPLQPLPPLPSNRNVFTVSASSIQKTGGVAGKFPQGPS--PESPSAAKGI 1463

Query: 1100 ASS-------SPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAG 1152
             S        SPA     +++T+    + GS+  LE S  D        + L +    + 
Sbjct: 1464 KSQGLRSLKISPATRAPPDEVTNR---KSGSN--LEKSNSDCE------NYLTIPLKGSS 1512

Query: 1153 TSGRLELPAQLERTASKPPAV---PPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKP 1209
             +G L          S+P A    PP +  A   +    S R +   + +    S   +P
Sbjct: 1513 AAGEL---------LSRPGASREGPPNSSAATLCSLPPLSARSQVPSSSKGSQVSGTSRP 1563

Query: 1210 C----PEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVH-----RHSVSGFSEPVGRRPGG 1260
                 P++  +T   P  P+  P H    +   PP        +  V  FS P    P  
Sbjct: 1564 AWRTKPDNPRETVAAPPGPQS-PEHPPTTIYHQPPLPFTLQGAQPQVLCFSPPSMPAPA- 1621

Query: 1261 PQSLTPLPAYPATQ--------KVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSI 1312
            P +  P+P  P  Q        K+L D  +G+Y++ D P+Q   +  +DPETG+YV V +
Sbjct: 1622 PAASAPVPTDPFQQAQPQQTQRKMLLDVTTGQYYLVDTPVQPMTRRLFDPETGQYVDVPM 1681

Query: 1313 PSSEGA----SPEPPP----PDALAAPYVLYPGFQP--VPVTALMP 1348
             S + A    S   PP    P A    Y++YPGF P  +P  AL P
Sbjct: 1682 TSQQQAVAPMSISVPPLALSPGAYGPTYMIYPGFLPTVLPTNALQP 1727



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 125/579 (21%), Positives = 203/579 (35%), Gaps = 108/579 (18%)

Query: 6    KKCTDAFSDSSSIGSVLDDADREVSSLTDRAFRSLCISEDTSFHDSYLAVSPDITRQVFG 65
            K+  D  S +SS  S LDDAD+EV +LT RAFRSL      + + S    S  ++   FG
Sbjct: 633  KELVDYSSGASSAVSELDDADKEVRNLTSRAFRSLAYPYFEALNISSRESSTTLSEVGFG 692

Query: 66   TFHQ------RTVGHTQRKSGIWSQLPSQGT---EHSGWAATFQQLPKYVQGEEKYPKTS 116
             +          VG    +S + S   S      + SG  AT  QL  Y+Q ++   K  
Sbjct: 693  RWSTFLDLKCGGVGARVEQSLLRSSAASVAAGLRKGSGARATADQL--YIQSKKSQTKA- 749

Query: 117  PPPTPVQRRLEVPVSGLRSSNKPV-------------SKVSTLIKSFDRTESQRCESRPT 163
                     LE  VS +    K V             S+V TL++  +     +  S P 
Sbjct: 750  ---------LEFVVSKVEGEIKHVETPLCFQKQVQTGSRVVTLLEPLNVRSESKASSAPG 800

Query: 164  ASKPPALKNPPKFAPLPENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQESSK 223
              +  A K P K              SA+        + S T + S    R  G Q+S  
Sbjct: 801  PGR--ATKGPGKGP-----------GSAYTD------DGSETSEGSKPTSRADGPQKSKF 841

Query: 224  NPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRG-KGTFLHSENSAFESWNA 282
               +  +  S  +   ++          + HH   T +   G +G+    E       + 
Sbjct: 842  ASSLLKNVISKKMQREHEFKMERGEVMDTSHHLSGTSKETEGARGSERQRERGLQRQSSR 901

Query: 283  H-----QPKLLERKDTA--GTVPESKAPKHYGDTTLLREPCP----PERTVSPCQVQASC 331
            H     +  ++   D    G+V  SK+P     T   R   P     +     C+++ S 
Sbjct: 902  HSEAGSEYTVVSMSDAGGEGSVAGSKSPVFKASTPRERNAGPGRNFTDGHTEVCEIKKSA 961

Query: 332  SQEENRLAAGALSTSI-PWGCRDPGAQVFAVEGKAPSSQPDSQEKPAQPPWRKPKTGKKG 390
            S+    +   + +++   W                   + +++++  Q P  K K  K G
Sbjct: 962  SETVKGIFLRSQNSAFRSW------------------KEKEAEKREEQAPIGKLKLPKGG 1003

Query: 391  --KESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLP---------VEPN----- 434
              +  L +    K     R      +  P+++     A   P         + P      
Sbjct: 1004 DWRADLGEISASKNTIMSRLFVPNIQQTPKDKQPRKQATKYPAAQATSTAVIRPKAPEIK 1063

Query: 435  ------EHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQS 488
                  +     FNI+KLLTP +    A  +      + + +      G   ++    Q 
Sbjct: 1064 IRLGSVQQPSSDFNIAKLLTPKLAGGSA-SNLFKTIEDNSRAQQKLFRGDNLEKVPHFQV 1122

Query: 489  RD-SYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEK 526
            RD   KSKA   L  ++DVRK +K +  SS    V  E+
Sbjct: 1123 RDIRDKSKAQGPLHQVRDVRKLIKGSGDSSDKGSVTPEQ 1161


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 112/508 (22%), Positives = 190/508 (37%), Gaps = 67/508 (13%)

Query: 212  PGRKHGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGE---PGRGKGT 268
            P  K  E+E +K+P        +  PA  +  +  E+K P     PV  E   P   K  
Sbjct: 562  PEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSP 621

Query: 269  FLHSENSAFESWNAHQPKLLERKDTAGTVPESKAPKHYGDTTLLREPCPPERTVSPCQVQ 328
                  S  E  +  + K    K+ A +  ++K+P+         E   PE+  SP + +
Sbjct: 622  VKEEAKSPAEVKSPEKAK-SPTKEEAKSPEKAKSPEK-------EEAKSPEKAKSPVKAE 673

Query: 329  ASCSQEENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPSSQPDSQEKPAQPPWRKPKTGK 388
            A  S E+ +    A + S P   + P  +    E K+P       EK   P   + K+ +
Sbjct: 674  AK-SPEKAKSPVKAEAKS-PEKAKSPVKE----EAKSP-------EKAKSPVKEEAKSPE 720

Query: 389  KGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISKLLT 448
            K K  +++  E KT    + P      +P++  S   A  L V+  E   P         
Sbjct: 721  KAKSPVKE--EAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTP--------- 769

Query: 449  PIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLK-DVR 507
                 + A   AD  P E+  SP  +    + K P + +S     +KAP      K +V+
Sbjct: 770  ---AKEEARSPADKFP-EKAKSPVKE----EVKSPEKAKSPLKEDAKAPEKEIPKKEEVK 821

Query: 508  KRVKSTYS------SSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESPPNELSKERP 561
              VK            P  K  +EK       +++  S     P      P  E  KE  
Sbjct: 822  SPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPA 881

Query: 562  ADDPTASHINPQKDPTADPSE-PSADSYLTLSTAPTIAKAPFYVNGEAAERSSYENKEVE 620
             + P  S +  +K+   D  + P+ +       AP  AK     + +  E++    KE +
Sbjct: 882  VEKPKESKVEAKKEEAEDKKKVPTPE-----KEAP--AKVEVKEDAKPKEKTEVAKKEPD 934

Query: 621  GELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPGGATEKMKTHQLENGLSRSVSQE- 679
                  P+  +   + +E  P K  +     + PE     EK KT        +++S+E 
Sbjct: 935  DAKAKEPSKPA---EKKEAAPEKKDTKEEKAKKPE-----EKPKTEAKAKEDDKTLSKEP 986

Query: 680  TEPEREAGLQNTHLNQKFFPGPLSPEEE 707
            ++P+ E   +++  +QK    P    E+
Sbjct: 987  SKPKAEKAEKSSSTDQKDSKPPEKATED 1014



 Score = 35.4 bits (80), Expect = 0.40
 Identities = 62/327 (18%), Positives = 125/327 (38%), Gaps = 44/327 (13%)

Query: 371 DSQEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLP 430
           + +EK A+    K + G  G+E   +  EE+T++    PP     +P+++ +++   +  
Sbjct: 472 EEEEKEAKEEEGKEEEG--GEEEEAEGGEEETKS----PPAEEAASPEKE-AKSPVKEEA 524

Query: 431 VEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRD 490
             P E   P    +K    +     + + A S   E   SPP   +  +E+  S  + + 
Sbjct: 525 KSPAEAKSPEKEEAKSPAEV----KSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKS 580

Query: 491 SYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEE 550
             K+K+P+     K+  K      S       + E+ +   + K  PV          E 
Sbjct: 581 PEKAKSPA-----KEEAKSPAEAKSPEKAKSPVKEEAKSPAEAK-SPVKE--------EA 626

Query: 551 SPPNELSKERPADDPTASHI-------NPQKDPTADPSEPSADSYLTLSTAPTIAKAPFY 603
             P E+     A  PT           +P+K+    P E +       + +P  AK+P  
Sbjct: 627 KSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSP-EKAKSPVKAEAKSPEKAKSPVK 685

Query: 604 VNGEAAERSSYENKE-----------VEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNR 652
              ++ E++    KE           V+ E +      S   +  +   +    ++   +
Sbjct: 686 AEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAK 745

Query: 653 DPEPGGATEKMKTHQLENGLSRSVSQE 679
            PE   + EK KT  +++  +++ ++E
Sbjct: 746 SPEKAKSPEKAKTLDVKSPEAKTPAKE 772



 Score = 31.6 bits (70), Expect = 5.7
 Identities = 87/482 (18%), Positives = 163/482 (33%), Gaps = 50/482 (10%)

Query: 761  SAGDSQKDEKENVMRKDELQYCALSNGHACLENRSQGEALQRERESV-------SGGRTR 813
            S  +++  EKE      E++    +   A  E +S  EA   E+E         S  + +
Sbjct: 526  SPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAK 585

Query: 814  KASAEEANFRGSWIGENKGTTFSQAKDLTPSPSSASNRHMLFTIKDNTLRATPVIKP--I 871
              + EEA          K    S  K+   SP+ A +      +K+       V  P   
Sbjct: 586  SPAKEEAKSPAEAKSPEKAK--SPVKEEAKSPAEAKS-----PVKEEAKSPAEVKSPEKA 638

Query: 872  MLPLLRTMSLEDSLSSGHKEEELPRPEWGEDPGFCAPENQDILGTSTPTNTRGT-RVKCM 930
              P        +   S  KEE    PE  + P     ++ +   +      +   + K  
Sbjct: 639  KSPTKEEAKSPEKAKSPEKEEA-KSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSP 697

Query: 931  ANEVMEDPGQGSSMARMEASQPAPKGNFPSMPLVGEGDRVKAPPDAAPGLVASNCKSGSA 990
              E  + P +  S  + EA  P  K   P        ++ K+P            K  + 
Sbjct: 698  VKEEAKSPEKAKSPVKEEAKSPE-KAKSPVKEEAKTPEKAKSP-----------VKEEAK 745

Query: 991  DSGKLAAPWHIPTIAL--PEGDIEDQPPPWQPENCWEEQTPG-FKSHFLSTPRAGPPGRR 1047
               K  +P    T+ +  PE     +     P + + E+     K    S  +A  P + 
Sbjct: 746  SPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLK- 804

Query: 1048 LVPSERANSPNPGSPGESSACSPAASNIWEESSQAPGGPELLPEEPNQASPWASSSPARV 1107
                E A +P    P +    SP       +  +    P+   EE   A+P   +   + 
Sbjct: 805  ----EDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATP--KTEEKKD 858

Query: 1108 TRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELPAQLERTA 1167
            +++E+       +    P +E   E      P+ S ++     A    ++  P +     
Sbjct: 859  SKKEEAPK----KEAPKPKVEEKKEPA-VEKPKESKVEAKKEEAEDKKKVPTPEK----- 908

Query: 1168 SKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRER 1227
              P  V  K +   +   ++A K     +A+E    +++ +  PE  +  +++   P E+
Sbjct: 909  EAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEK 968

Query: 1228 PR 1229
            P+
Sbjct: 969  PK 970


>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
           homolog 2 [Homo sapiens]
          Length = 1210

 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 131/560 (23%), Positives = 204/560 (36%), Gaps = 84/560 (15%)

Query: 123 QRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTESQRCESRPTASKPPALKNPPKFAP--LP 180
           Q + +   S    SN      S L      ++S+  +S  T  KPP+   PP  AP  LP
Sbjct: 400 QNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPS-APQSLP 458

Query: 181 ENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQESSKNPEMACHGSSSFLPAAN 240
           E   +    SA        +E ++   +S     +    +S +N  +         P  N
Sbjct: 459 EPVASAHSSSA-------ESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTN 511

Query: 241 ----DTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENSAFESWNAHQPKLLERKDTAGT 296
               D      S+  +P   P + EP R       S +SA    ++       +  +   
Sbjct: 512 KWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAP 571

Query: 297 VPESKAPKHYGDTTLLREPC---PPER-TVSPCQ----VQASCSQEENRLAAGALSTS-I 347
               +AP H G  +  + P    PP+R TV   Q    V+AS          G      +
Sbjct: 572 RAPPEAP-HPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLL 630

Query: 348 PWGCRDPGAQ---VFAVEGKAPSSQPDSQEKPAQPPWRKPKTGK----------KGKESL 394
           P+G RD  ++       +G+ P +   ++ KPA PP  + K  K           G E  
Sbjct: 631 PYGSRDQTSKDKPKVKTKGR-PRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPA 689

Query: 395 QDTLEEKTQ--------TNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDP---PFNI 443
           +D +E++T         T  +GPP    H+     +      + V+ +   D    P   
Sbjct: 690 KDNVEDRTPEHFALVPLTESQGPP----HSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRD 745

Query: 444 SKLLTPI---IPSKHALDSADSQPAERTPSPPG---QLNGYQEKEP-------SECQSRD 490
           +KLL+P+    P +  +         R P PPG   +    ++K+P       SE +S D
Sbjct: 746 TKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSD 805

Query: 491 S-------YKSKAPSLLFNLK-DVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGV 542
           S        K +A     N K  + K +KS  SSS        KT+      Q   S   
Sbjct: 806 SSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQS--SKKE 863

Query: 543 ILPNGLEESPPNELSKERPADDPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAKAPF 602
           +LP      PP   S ++PA  P       + D        SA S  +     +I K   
Sbjct: 864 MLP-----PPPVSSSSQKPA-KPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQR- 916

Query: 603 YVNGEAAERSSYENKEVEGE 622
            V G+ + RSS E+K   G+
Sbjct: 917 RVEGKGS-RSSSEHKGSSGD 935



 Score = 38.9 bits (89), Expect = 0.036
 Identities = 110/535 (20%), Positives = 188/535 (35%), Gaps = 104/535 (19%)

Query: 113 PKTSPPPTPVQ-RRLEVPVSGLRSSNKPVSKV----STLIKSFDRTESQRCESRPTASKP 167
           P  SP    V+    E P   L +  +P S+     S   KS    +      RP   + 
Sbjct: 242 PAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQD 301

Query: 168 PALKNPPKFAPLPENSVNFCFD--------SAFLTVRRVPAE-VSNTHQNSYQPGRKHGE 218
            A    P+  PLPE+     F+         A LT  ++P++ V  T+ N       H  
Sbjct: 302 QAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEV-----HCV 356

Query: 219 QESSKNPEMACHGSSSFLPAANDTATLCESKFPSP----HHKPVTGEPGRGKGTFLHSEN 274
           +E  K  EM  H     L A +  +T   SKFP P     H     +  +   T   + +
Sbjct: 357 EEILK--EMT-HSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHS 413

Query: 275 SAFESWNAHQPKLLERKDTAGTVPESKAPKHYGDTTLLREPCPPERTVSPCQVQASCSQE 334
           ++ +  ++     L+  D+  +  E    K    +     P  P+    P    A  S  
Sbjct: 414 NSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSA---PPSAPQSLPEPV-ASAHSSSA 469

Query: 335 ENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPSSQPDSQE-KPAQPPWRKPKTGKKGKES 393
           E+   + + S+S               + ++ SS  DS+E +P + P  +P+     K  
Sbjct: 470 ESESTSDSDSSS---------------DSESESSSSDSEENEPLETPAPEPEPPTTNKWQ 514

Query: 394 LQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISKLLTPIIPS 453
           L + L + +Q      P      P+             EP   +               S
Sbjct: 515 LDNWLTKVSQ------PAAPPEGPRS-----------TEPPRRHP-------------ES 544

Query: 454 KHALDSADSQPAERTPSPPGQLNGYQEKEPSE--------CQSRDSYKSKAPSLLFNLKD 505
           K + DSA SQ    +  PP + +    + P E        CQ   + +          K 
Sbjct: 545 KGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQ 604

Query: 506 VRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESPPNELSKERPADDP 565
            +K VK++  +          +R  + G++EP     +LP G  +    +  K +    P
Sbjct: 605 PKKPVKASARAG---------SRTSLQGEREP----GLLPYGSRDQTSKDKPKVKTKGRP 651

Query: 566 TASHINPQKDPTADPSEPSADSYLTLSTAPTIAKAPFYVNGEAAERSSYENKEVE 620
            A+  N  K        PS++     S+ P  +KA   ++G    + + E++  E
Sbjct: 652 RAAASNEPKPAV----PPSSEKKKHKSSLPAPSKA---LSGPEPAKDNVEDRTPE 699



 Score = 31.6 bits (70), Expect = 5.7
 Identities = 54/261 (20%), Positives = 94/261 (36%), Gaps = 23/261 (8%)

Query: 1043 PPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPGGPELLPEEPNQASPWASS 1102
            PP     PS   + P P +   SS+    +++  + SS +         E N+     + 
Sbjct: 444  PPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAP 503

Query: 1103 SPARVTRRE---DLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLEL 1159
             P   T  +   D     V +  + P    S E  R         D ATS   +  +   
Sbjct: 504  EPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPP 563

Query: 1160 PAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKPCP-------- 1211
            P    +++SK P  PP+     +R+ + +  +++  Q Q   G  Q  KP          
Sbjct: 564  P----KSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTV-GTKQPKKPVKASARAGSR 618

Query: 1212 EDLEQTQQRPLCP---RERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLP 1268
              L+  ++  L P   R++   + P V++   P      +  +EP    P   +      
Sbjct: 619  TSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRP----RAAASNEPKPAVPPSSEKKKHKS 674

Query: 1269 AYPATQKVLQDPQSGEYFVFD 1289
            + PA  K L  P+  +  V D
Sbjct: 675  SLPAPSKALSGPEPAKDNVED 695


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 96/399 (24%), Positives = 150/399 (37%), Gaps = 55/399 (13%)

Query: 1038 TPRAGPPGRRLVPS---ERANSPNPGSPGESSACSPAASNIWEESSQAPGGPELLPEEPN 1094
            +PR   P RR+ P     R+ SP       S++ S ++S+     S++P      P++P 
Sbjct: 322  SPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSP------PKKP- 374

Query: 1095 QASPWASSSPARVTRREDLT-------HALVWEGGSDPLLELSAEDLRTLSPRGSLLDVA 1147
               P  +SSP R TRR   +       H         P    S    ++   R S + V 
Sbjct: 375  ---PKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSV- 430

Query: 1148 TSPAGTSGRLELPAQLERTASKPPAVPPK----TEKALRRAKKLAS----KRRKTDQAQE 1199
             SP  TSG++      E+  S  PA  P+    +E    +  K+A+    ++R+  + Q 
Sbjct: 431  -SPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQN 489

Query: 1200 KHGESQEGKPCPEDLEQTQQRPLCPRE--RPRHNFPVVRSLPPPVHRHSVSGFSEPVGRR 1257
            +   S  G     + E+ ++  +   E  R R + P   + P P  R      + P GRR
Sbjct: 490  QQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKE---TSPRGRR 546

Query: 1258 PGGP------QSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQ--VKIKTFYDPETGKYVK 1309
               P      +  +P PA P  ++    P          P +     + +  P   +Y  
Sbjct: 547  RRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSP 606

Query: 1310 VSIPSSEGASPEPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASA 1369
               P    ASP PPPP   A+P        P P   +       Q S+P   R+ P  S+
Sbjct: 607  SPPPKRRTASP-PPPPKRRASP-------SPPPKRRVSHSPPPKQRSSPVTKRRSPSLSS 658

Query: 1370 ARARTQSVHESGLQL-DPGPHGDCTPHSAGQRPHGPPQS 1407
               +  S   S  +   P P+     HS   RP  P  S
Sbjct: 659  KHRKGSSPSRSTREARSPQPN---KRHSPSPRPRAPQTS 694



 Score = 44.3 bits (103), Expect = 9e-04
 Identities = 159/721 (22%), Positives = 231/721 (32%), Gaps = 149/721 (20%)

Query: 742  DQQKMWFTENQREDRRKDVSAGDSQKDEKENVMRKDELQYCALSNGHACLENRSQGEALQ 801
            +Q+K+   + Q ED+ K        K+EKE+   K E               R +   ++
Sbjct: 137  EQEKLASMKKQDEDKDK------RDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVR 190

Query: 802  RERESVSGGRTRKASAEEANFRGSWIGENKGTTFSQAKDLTPSPSSASNRHMLFTIKDNT 861
            RER+       R  +   +            +   + K+ TP     S +    ++++ T
Sbjct: 191  RERKRSHSRSPRHRTKSRSP-----------SPAPEKKEKTPELPEPSVKVKEPSVQEAT 239

Query: 862  LRAT--PVIKPIMLPLLRTMSLEDSLSSGHKEEELPRPEWGEDPGFCAPENQDILGTSTP 919
              +    V KP  +P  +  S E + S   KE+E  RP           +++    + +P
Sbjct: 240  STSDILKVPKPEPIPEPKEPSPEKN-SKKEKEKEKTRPR-----SRSRSKSRSRTRSRSP 293

Query: 920  TNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAPKGNFPS--MPLVGEGDRVKAPPDAA 977
            ++TR  R +  +      P +  S  R    +P+P+   P   MP      R ++P    
Sbjct: 294  SHTRPRR-RHRSRSRSYSPRRRPSPRR----RPSPRRRTPPRRMPPPPRHRRSRSPVRRR 348

Query: 978  PGLVASNCKSGSADSGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFKSHFLS 1037
                AS   S S+ S                     + PP +P       +P  K+  LS
Sbjct: 349  RRSSASLSGSSSSSSSS-----------------RSRSPPKKPPK--RTSSPPRKTRRLS 389

Query: 1038 TPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEES--SQAPGGPELLPEEPNQ 1095
             P A PP RR  PS  A  P    P    + +P  SN   +S  S +PG       +   
Sbjct: 390  -PSASPPRRRHRPSPPATPP----PKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKG 444

Query: 1096 ASPWASSSPARVTRREDLTHALVWEGG----------------------SDPLLELSAED 1133
                 S SPA   R+ +L+ +   +GG                      SD     S+ED
Sbjct: 445  TEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSED 504

Query: 1134 ---------------------LRTLSPRGSLLDVATSPAGTSGRLELPAQLERTASKPPA 1172
                                  R+ SP        TSP G   R   P    R  S  PA
Sbjct: 505  ERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPA 564

Query: 1173 VPPK-----TEKALRRAKKLASKRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRER 1227
             PP+     T    RR      +RR     +      +   P P    +T   P  P+ R
Sbjct: 565  PPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRR 624

Query: 1228 PRHNFPVVRSL---PPPVHRHSV--------------SGFS------EPVGRRPGGPQSL 1264
               + P  R +   PPP  R S                G S      E    +P    S 
Sbjct: 625  ASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSP 684

Query: 1265 TPLPAYPATQK--------VLQDPQSGEY---------FVFDLPLQVKIKTFYDPETGKY 1307
            +P P  P T              PQ  +           V   P   KIK    P     
Sbjct: 685  SPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSV 744

Query: 1308 VKVSIPSSEGASPEPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRA 1367
             +VS   S   SPEP      A P    P     P T   P     +  +PT     PR 
Sbjct: 745  RRVSSSRSVSGSPEPAAKKPPAPP---SPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRN 801

Query: 1368 S 1368
            S
Sbjct: 802  S 802



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 115/519 (22%), Positives = 175/519 (33%), Gaps = 96/519 (18%)

Query: 113 PKTSPPP-------TPVQRRLE--VPVSGLRSSNKPVSKVSTLIKSFDRTESQRCESR-- 161
           P+  PPP       +PV+RR      +SG  SS+      S   K   RT S   ++R  
Sbjct: 329 PRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRL 388

Query: 162 -PTASKP-------PALKNPPK--FAPLPENSVNFCFDSAFLTVRRVPAEVSN----THQ 207
            P+AS P       P    PPK   +P P+ S         ++  R   +V+       +
Sbjct: 389 SPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKR 448

Query: 208 NSYQPGRKH-----GEQESSKNPEMACHGS--------SSFLPAANDTATLCESKFPSPH 254
            S  P  K       E E  K  +MA   S             +++D+ +   S+   P 
Sbjct: 449 ESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPK 508

Query: 255 HKPV-TGEPGRGKGTFLHSENSAFESWNAHQPKLLERKDTAGTVPESKAPKHYGDTTLLR 313
              V  GE GR +       +S   S +    K  +     G    S +P     T   R
Sbjct: 509 RSHVKNGEVGRRR------RHSPSRSASPSPRKRQKETSPRGRRRRSPSPP---PTRRRR 559

Query: 314 EPCPP-----ERTVSPCQVQASCSQEENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPSS 368
            P P       RT +P   + + S    R +      S P   R   +        +P  
Sbjct: 560 SPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPP 619

Query: 369 QPDSQEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALD 428
            P  +  P+ PP R+       K+           T +R P L +KH      S +    
Sbjct: 620 PPKRRASPSPPPKRRVSHSPPPKQ------RSSPVTKRRSPSLSSKHRKGSSPSRSTREA 673

Query: 429 LPVEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAER---TPSPPGQLNGYQEKEPSE 485
              +PN+ + P            P   A  ++ S P  R   + SP  +    Q   PS 
Sbjct: 674 RSPQPNKRHSPS-----------PRPRAPQTSSSPPPVRRGASSSPQRR----QSPSPST 718

Query: 486 CQSRDSYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILP 545
              R   ++  P          K++K   S SP   V    +   V G  EP +      
Sbjct: 719 RPIRRVSRTPEP----------KKIKKAASPSP-QSVRRVSSSRSVSGSPEPAAK----- 762

Query: 546 NGLEESPPNELSKERPADD-PTASHINPQKDPTADPSEP 583
                +PP+ +  + P+ +   A  +   K PT  PS P
Sbjct: 763 --KPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPP 799



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 74/315 (23%), Positives = 113/315 (35%), Gaps = 66/315 (20%)

Query: 116 SPPPTPVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTESQRCESRP-----TASKPPAL 170
           SP P P +RR   P    R+ + P  + S   + +     +R    P     TAS PP  
Sbjct: 562 SPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPP 621

Query: 171 KNPPKFAPLPENSVNFC----FDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQES----- 221
           K     +P P+  V+        S+ +T RR P+ +S+ H+    P R   E  S     
Sbjct: 622 KRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPS-LSSKHRKGSSPSRSTREARSPQPNK 680

Query: 222 --SKNPEMACHGSSSFLPAANDTATLCESK--FPSPHHKPV-----TGEPGRGKGTFLHS 272
             S +P      +SS  P     A+    +   PSP  +P+     T EP + K     S
Sbjct: 681 RHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPS 740

Query: 273 ENSAFESWNAHQPKLLERKDTAGTVPESKAPKHYGDTTLLREPCPPERTVSPCQVQASCS 332
                       P+ + R  ++ +V  S  P         + P PP    SP Q Q    
Sbjct: 741 ------------PQSVRRVSSSRSVSGSPEP------AAKKPPAPP----SPVQSQ---- 774

Query: 333 QEENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPSSQPDSQEKPAQPPWRKPKTGKKGKE 392
                      S S  W    P       + K+P+  P       Q    K K  KK K+
Sbjct: 775 -----------SPSTNWSPAVP-----VKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKK 818

Query: 393 SLQDTLEEKTQTNQR 407
             +D   +K + +++
Sbjct: 819 HKKDKKHKKHKKHKK 833



 Score = 34.3 bits (77), Expect = 0.89
 Identities = 49/218 (22%), Positives = 88/218 (40%), Gaps = 29/218 (13%)

Query: 1007 PEGDIEDQPPPWQPEN-CWEEQTPGFKSHFL---STPRAGPPGRRLVPSERAN-SPNPGS 1061
            P+  +   PPP Q  +   + ++P   S      S  R+    R   P++R + SP P +
Sbjct: 631  PKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRA 690

Query: 1062 PGESSACSP----AASNIWEESSQAPGGPELL----PEEPNQASPWASSSPARVTRREDL 1113
            P  SS+  P    A+S+     S +P    +       EP +    AS SP  V R   +
Sbjct: 691  PQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR---V 747

Query: 1114 THALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELPAQLERTASKPPAV 1173
            + +    G  +P  +          P      V +    T+    +P +  ++ +  P+ 
Sbjct: 748  SSSRSVSGSPEPAAK---------KPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPS- 797

Query: 1174 PPKT---EKALRRAKKLASKRRKTDQAQEKHGESQEGK 1208
            PP+    E   ++ KK   K+ K D+  +KH + ++ K
Sbjct: 798  PPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEK 835



 Score = 31.2 bits (69), Expect = 7.5
 Identities = 88/429 (20%), Positives = 155/429 (36%), Gaps = 67/429 (15%)

Query: 368 SQPDSQEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNAL 427
           S  + +E+   P  RK ++    + S      E+ +++ R P   TK        E    
Sbjct: 161 SSREKRERSRSPRRRKSRSPSPRRRS-SPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEK 219

Query: 428 --DLPVEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSE 485
             +LP    +  +P    +   + I+     +   +  P  + PSP       +EKE + 
Sbjct: 220 TPELPEPSVKVKEPSVQEATSTSDILK----VPKPEPIPEPKEPSPEKNSKKEKEKEKTR 275

Query: 486 CQSRDSYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILP 545
            +SR   KS++          R R +S   + P  +            +  P       P
Sbjct: 276 PRSRSRSKSRS----------RTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRR----P 321

Query: 546 NGLEESPPNELSKERPADDPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAKAPFYVN 605
           +    +PP  +    P    + S +  ++  +A  S  S+ S  + S +P   K P    
Sbjct: 322 SPRRRTPPRRMPPP-PRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSP--PKKP---- 374

Query: 606 GEAAERSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPGGATEKMKT 665
               +R+S   ++      + P+ S   P  R HRP         +    P   T    T
Sbjct: 375 ---PKRTSSPPRKTR---RLSPSAS---PPRRRHRP---------SPPATPPPKTRHSPT 416

Query: 666 HQLENGLSRSVSQETEPEREAGLQNTH--LNQKFFPGPLSPEEEDVFYSDSQSD------ 717
            Q  N  +R       P R +G    H    ++  P P +P+   V  S+S+ D      
Sbjct: 417 PQQSN-RTRKSRVSVSPGRTSGKVTKHKGTEKRESPSP-APKPRKVELSESEEDKGGKMA 474

Query: 718 FMPSLKGKAKF------STSSSDQSFASFDDQQKMWFTENQREDRRKDVSAGDS-----Q 766
              S++ + ++      S+S S  S +S D++ K    +N    RR+  S   S     +
Sbjct: 475 AADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPR 534

Query: 767 KDEKENVMR 775
           K +KE   R
Sbjct: 535 KRQKETSPR 543


>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
            [Homo sapiens]
          Length = 1451

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 111/490 (22%), Positives = 166/490 (33%), Gaps = 80/490 (16%)

Query: 884  SLSSGHKEEELPRPEWGEDPGFCAPENQDILGTSTPTNTR-----GTRVKCMANEVMEDP 938
            S S   +EEE    E  +     A  N  +LG   P++ +      T         M  P
Sbjct: 83   STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP 142

Query: 939  GQGSSMARMEASQPAPKGNFPS--MPLVGEGDRVKAPP----DAAPGLV-ASNCKSGSAD 991
              G ++A + + +   K   PS    LV E +   + P     A PG+V A    S S D
Sbjct: 143  ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSED 202

Query: 992  SGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFKSHFLS------TPR----A 1041
            +   +    +      EG    +P   +  +   +++P  K+          TP+    A
Sbjct: 203  TSSSSDETDV------EGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGA 256

Query: 1042 GPPGRRL-VPSERANSPNPGSPGESSACSPAASNI-------WEESSQAPG----GPELL 1089
             PP +R   P E + S   GS  E  A +   S +          ++ AP     G    
Sbjct: 257  LPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGAT 316

Query: 1090 PEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATS 1149
            P  P +A   AS + A     +        E  S+   E S  +  T + +  L   A+ 
Sbjct: 317  PAPPGKAGAVASQTKAGKPEEDS-------ESSSE---ESSDSEEETPAAKALLQAKASG 366

Query: 1150 PAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKP 1209
                 G    PA+        PA P KT  A+  AK  A KR +  Q+  +  +S+E  P
Sbjct: 367  KTSQVGAASAPAKESPRKGAAPAPPGKTGPAV--AKAQAGKREEDSQSSSEESDSEEEAP 424

Query: 1210 CPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPA 1269
                           + +P    P VR+   P         S   G  P  P+   P  A
Sbjct: 425  A--------------QAKPSGKAPQVRAASAPAKE------SPRKGAAPAPPRKTGPAAA 464

Query: 1270 YPATQKVLQDPQ-SGEYFVFDLPLQVKIKTFYDPETGKYVKVSI-------PSSEGASPE 1321
                 K  +D + S E    D      +        GK  +V         P  +GA P 
Sbjct: 465  QVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPV 524

Query: 1322 PPPPDALAAP 1331
            PP     A P
Sbjct: 525  PPGKVGPATP 534


>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
            [Homo sapiens]
          Length = 1488

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 111/490 (22%), Positives = 166/490 (33%), Gaps = 80/490 (16%)

Query: 884  SLSSGHKEEELPRPEWGEDPGFCAPENQDILGTSTPTNTR-----GTRVKCMANEVMEDP 938
            S S   +EEE    E  +     A  N  +LG   P++ +      T         M  P
Sbjct: 83   STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP 142

Query: 939  GQGSSMARMEASQPAPKGNFPS--MPLVGEGDRVKAPP----DAAPGLV-ASNCKSGSAD 991
              G ++A + + +   K   PS    LV E +   + P     A PG+V A    S S D
Sbjct: 143  ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSED 202

Query: 992  SGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFKSHFLS------TPR----A 1041
            +   +    +      EG    +P   +  +   +++P  K+          TP+    A
Sbjct: 203  TSSSSDETDV------EGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGA 256

Query: 1042 GPPGRRL-VPSERANSPNPGSPGESSACSPAASNI-------WEESSQAPG----GPELL 1089
             PP +R   P E + S   GS  E  A +   S +          ++ AP     G    
Sbjct: 257  LPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGAT 316

Query: 1090 PEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATS 1149
            P  P +A   AS + A     +        E  S+   E S  +  T + +  L   A+ 
Sbjct: 317  PAPPGKAGAVASQTKAGKPEEDS-------ESSSE---ESSDSEEETPAAKALLQAKASG 366

Query: 1150 PAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKP 1209
                 G    PA+        PA P KT  A+  AK  A KR +  Q+  +  +S+E  P
Sbjct: 367  KTSQVGAASAPAKESPRKGAAPAPPGKTGPAV--AKAQAGKREEDSQSSSEESDSEEEAP 424

Query: 1210 CPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPA 1269
                           + +P    P VR+   P         S   G  P  P+   P  A
Sbjct: 425  A--------------QAKPSGKAPQVRAASAPAKE------SPRKGAAPAPPRKTGPAAA 464

Query: 1270 YPATQKVLQDPQ-SGEYFVFDLPLQVKIKTFYDPETGKYVKVSI-------PSSEGASPE 1321
                 K  +D + S E    D      +        GK  +V         P  +GA P 
Sbjct: 465  QVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPV 524

Query: 1322 PPPPDALAAP 1331
            PP     A P
Sbjct: 525  PPGKVGPATP 534


>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
            sapiens]
          Length = 1450

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 111/490 (22%), Positives = 166/490 (33%), Gaps = 80/490 (16%)

Query: 884  SLSSGHKEEELPRPEWGEDPGFCAPENQDILGTSTPTNTR-----GTRVKCMANEVMEDP 938
            S S   +EEE    E  +     A  N  +LG   P++ +      T         M  P
Sbjct: 83   STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP 142

Query: 939  GQGSSMARMEASQPAPKGNFPS--MPLVGEGDRVKAPP----DAAPGLV-ASNCKSGSAD 991
              G ++A + + +   K   PS    LV E +   + P     A PG+V A    S S D
Sbjct: 143  ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSED 202

Query: 992  SGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFKSHFLS------TPR----A 1041
            +   +    +      EG    +P   +  +   +++P  K+          TP+    A
Sbjct: 203  TSSSSDETDV------EGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGA 256

Query: 1042 GPPGRRL-VPSERANSPNPGSPGESSACSPAASNI-------WEESSQAPG----GPELL 1089
             PP +R   P E + S   GS  E  A +   S +          ++ AP     G    
Sbjct: 257  LPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGAT 316

Query: 1090 PEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATS 1149
            P  P +A   AS + A     +        E  S+   E S  +  T + +  L   A+ 
Sbjct: 317  PAPPGKAGAVASQTKAGKPEEDS-------ESSSE---ESSDSEEETPAAKALLQAKASG 366

Query: 1150 PAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKP 1209
                 G    PA+        PA P KT  A+  AK  A KR +  Q+  +  +S+E  P
Sbjct: 367  KTSQVGAASAPAKESPRKGAAPAPPGKTGPAV--AKAQAGKREEDSQSSSEESDSEEEAP 424

Query: 1210 CPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPA 1269
                           + +P    P VR+   P         S   G  P  P+   P  A
Sbjct: 425  A--------------QAKPSGKAPQVRAASAPAKE------SPRKGAAPAPPRKTGPAAA 464

Query: 1270 YPATQKVLQDPQ-SGEYFVFDLPLQVKIKTFYDPETGKYVKVSI-------PSSEGASPE 1321
                 K  +D + S E    D      +        GK  +V         P  +GA P 
Sbjct: 465  QVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPV 524

Query: 1322 PPPPDALAAP 1331
            PP     A P
Sbjct: 525  PPGKVGPATP 534


>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c [Homo
            sapiens]
          Length = 958

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 111/490 (22%), Positives = 166/490 (33%), Gaps = 80/490 (16%)

Query: 884  SLSSGHKEEELPRPEWGEDPGFCAPENQDILGTSTPTNTR-----GTRVKCMANEVMEDP 938
            S S   +EEE    E  +     A  N  +LG   P++ +      T         M  P
Sbjct: 83   STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP 142

Query: 939  GQGSSMARMEASQPAPKGNFPS--MPLVGEGDRVKAPP----DAAPGLV-ASNCKSGSAD 991
              G ++A + + +   K   PS    LV E +   + P     A PG+V A    S S D
Sbjct: 143  ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSED 202

Query: 992  SGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFKSHFLS------TPR----A 1041
            +   +    +      EG    +P   +  +   +++P  K+          TP+    A
Sbjct: 203  TSSSSDETDV------EGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGA 256

Query: 1042 GPPGRRL-VPSERANSPNPGSPGESSACSPAASNI-------WEESSQAPG----GPELL 1089
             PP +R   P E + S   GS  E  A +   S +          ++ AP     G    
Sbjct: 257  LPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGAT 316

Query: 1090 PEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATS 1149
            P  P +A   AS + A     +        E  S+   E S  +  T + +  L   A+ 
Sbjct: 317  PAPPGKAGAVASQTKAGKPEEDS-------ESSSE---ESSDSEEETPAAKALLQAKASG 366

Query: 1150 PAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKP 1209
                 G    PA+        PA P KT  A+  AK  A KR +  Q+  +  +S+E  P
Sbjct: 367  KTSQVGAASAPAKESPRKGAAPAPPGKTGPAV--AKAQAGKREEDSQSSSEESDSEEEAP 424

Query: 1210 CPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPA 1269
                           + +P    P VR+   P         S   G  P  P+   P  A
Sbjct: 425  A--------------QAKPSGKAPQVRAASAPAKE------SPRKGAAPAPPRKTGPAAA 464

Query: 1270 YPATQKVLQDPQ-SGEYFVFDLPLQVKIKTFYDPETGKYVKVSI-------PSSEGASPE 1321
                 K  +D + S E    D      +        GK  +V         P  +GA P 
Sbjct: 465  QVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPV 524

Query: 1322 PPPPDALAAP 1331
            PP     A P
Sbjct: 525  PPGKVGPATP 534


>gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo
            sapiens]
          Length = 1393

 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 247/1249 (19%), Positives = 404/1249 (32%), Gaps = 238/1249 (19%)

Query: 137  NKPVSKVSTLIKSFDRTESQRCESRPTASKPPALKNPPKFAPLPENSVNFCFDSAFLTVR 196
            +KP  K +   K+ D   S      P  S+              ENS N   D      R
Sbjct: 93   SKPTDKPTGNSKTIDHKSSTDNHEAPPTSE--------------ENSSNQGKDPMIRNQR 138

Query: 197  RV-PAEVSNTHQNSYQPGRKH--GEQESSKNPEMACHGSSSFLPAANDTATLCES----- 248
             V PA+ + TH+ S   G+KH     +S  N   +  G S+    ++ T    E      
Sbjct: 139  SVDPADSTTTHKES--AGKKHITPAPKSKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTL 196

Query: 249  -KFPSPHHKPVTGEPGRGKGTFLHSENSAFESWNAHQPKLLERKDTAGTVPESKAPKHYG 307
             K  +  HK  T     G         S  E   A      +   T GT PE        
Sbjct: 197  DKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYK---TTGT-PEESEKTEDS 252

Query: 308  DTTLLREPCPPERTVSPCQVQASCSQEENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPS 367
             TT+  +    + T             +  ++A  L+ S+       G    A E   PS
Sbjct: 253  RTTVASDKLLTKTT----------KNIQETISANELTQSLAEPTEHGGRT--ANENNTPS 300

Query: 368  SQPDSQEKPAQPPWRKPKTGKKGK--------ESLQDTLEEKTQTNQRGPPLYTKHNPQE 419
                    PA+P   + +T  +          E+ + T  E T     GP      N + 
Sbjct: 301  --------PAEPTENRERTANENTTLSPAEPIENRERTANENTAPFPAGPT----ENREM 348

Query: 420  QFSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKH----ALDSADSQPAE--------- 466
              +EN  L  P EP EH +   N +   +P  P++H    A ++    PAE         
Sbjct: 349  TANENTTL-FPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTP 407

Query: 467  ----RTPSPPGQLNGYQEK-------------EPSECQSRDSYKSKAPSLLFNLKDVRKR 509
                +T S   +   + E+             EP+E + R + ++  PS     ++    
Sbjct: 408  FANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETT 467

Query: 510  VKSTYSSSPLLKVLDEKTRGK---VDGKQEPVSNGVILPNGLEESP-------------- 552
                 + SP+    + +T           EP  NG   P   E++               
Sbjct: 468  ANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTP 527

Query: 553  -PNELSKERPADDPTASHINPQKDPTADPSEPSADSYLT----LSTAPTIAKAPFYVNGE 607
              NE +   PA+          +  T  P+EP+ +   T      T P++A+       E
Sbjct: 528  LANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPT-----E 582

Query: 608  AAERSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPGGATEKMKTHQ 667
              +R+ + N++           +S   +  EH  R  L+    N  P P   TE  +   
Sbjct: 583  NGQRTPFANEKT----------TSSSAEPTEHEERTPLANE--NTTPSPAEPTENRE--- 627

Query: 668  LENGLSRSVSQETEPEREAGLQNTHL--NQK--FFPG-PLSPEEEDVFYSDSQSDFMPSL 722
                  R+ ++ T P      +N  +  N+K   FP  P    E       + S   P+ 
Sbjct: 628  ------RTANENTTPSPAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTE 681

Query: 723  KGK----AKFSTSSSDQSFASFDDQQKMWFTENQREDRRKDVSAGDSQKDEKENVMRKDE 778
             G+    A   T+SS        ++  +   EN      +     +   +EK      + 
Sbjct: 682  NGQRTPFANEKTTSSSAEPTEHGERTPL-ANENTTLSPAEPTENRERTANEKTTPFPAEP 740

Query: 779  LQYCALSNGHACLENRSQGEALQRERESVSGGRTRKASAEEANFRGSWIGENKGTTFSQA 838
             +    +      EN +   A   E    +G RT  A+ +            K T F+  
Sbjct: 741  TE----NRERTANENTTPSPAQPTE----NGDRTPLANEKTTPSLAEPTENGKRTPFANE 792

Query: 839  KDLTPSPSSASNRHMLFTIKDNTLRA----------TPVIKPIMLPLLRTMSLEDSLSSG 888
            K  + S     +        +NT  +          T   K    P   T + E + +  
Sbjct: 793  KTTSSSAEPTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTAN-- 850

Query: 889  HKEEELPRP-EWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVM----EDPGQGSS 943
              E+  P P E  E+  + A EN  +   S    T    +  +ANE       +P +   
Sbjct: 851  --EKTTPFPAEPTENREWTANENTTL---SPAEPTEHEEMTPLANEKTTLSPAEPTENGE 905

Query: 944  MARMEASQPAPKGNFPSMPLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIPT 1003
                   +  P    P+      G+R     +      A   + G   + + A P     
Sbjct: 906  RTPFTNEKTTPSSAEPT----EHGERTPLANEITTPSRAEPTEHGERIANEKATPSPAKP 961

Query: 1004 IALPEGDIEDQPPPWQPENCWE-EQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSP 1062
                E  + +   P   E     E+TP    +  ++P           +E+  +P+P  P
Sbjct: 962  TEHGETTVNEDTTPSSAEPTENGERTPLANENTTTSPTESTEHGERTANEK-TTPSPAEP 1020

Query: 1063 GESSACSPAASNIWEESSQAPGGPELLPEEPNQASPWASSSPARVTRREDLTH------A 1116
             E    +P+A+   E++  +P  P    E    A+   + SP + T   + T        
Sbjct: 1021 TEHGERTPSAN---EKTIPSPAKPTEHEEMTPSANENTTPSPVKPTEHGEKTTLANEKIT 1077

Query: 1117 LVWEGGSD--------------PLLELSAEDLRTLSPRGSLLDVATSPA-----GTSGRL 1157
            L  EG ++               L + +    RT SP   +   A          TS  +
Sbjct: 1078 LSPEGPTEHGAKTTSANEKITPSLAKPTEHGERTTSPNDKITSSAAESTEHRDRATSANV 1137

Query: 1158 ELPAQLE------RTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEK---HGES---Q 1205
              PA  E      RT      +   TEK+    +K  S   KT +  EK   + E     
Sbjct: 1138 ITPAPAEPIKHAKRTTLAHEKMTQVTEKSTEHPEKTTSTTEKTTRTPEKPTLYSEKTICT 1197

Query: 1206 EGK--PCPED----------LEQTQQRPLCPRERPRHNFPVVRSLPPPV 1242
            +GK  P PE             +T + P+   E P     V +++ P V
Sbjct: 1198 KGKNTPVPEKPTENLGNTTLTTETIKAPVKSTENPEKTAAVTKTIKPSV 1246


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 855

 Score = 51.2 bits (121), Expect = 7e-06
 Identities = 135/591 (22%), Positives = 198/591 (33%), Gaps = 88/591 (14%)

Query: 810  GRTRKASAEEANFRGSWIGENKGTTFSQAKDLTPSPSSASNRHMLFTIKDNTLRATPVIK 869
            G TR A     N         +G     AK+ +P P S+  R         T R  P+ +
Sbjct: 78   GPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGR------ASGTTRPGPLGQ 131

Query: 870  PIMLPLLRTMSLEDSLSSGHKEEELPRPEWGEDPGFCAPENQDILGTS--TPTNTRGTRV 927
              +      +S E++++ G K  E P+          A   +D  G +  TP+     R 
Sbjct: 132  KGL-----RISAEETVARG-KATEAPKRS-----ALSAGARRDTSGPTPGTPSPAMARRS 180

Query: 928  KCMANEV----------MEDPGQG-----SSMARMEASQPAPKGNFPSMPLVGEGDRVKA 972
            +    EV             P +G     SS +    ++P+P       P  G G +  A
Sbjct: 181  RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAAR--RRPSAGGGLQRPA 238

Query: 973  PPDAAPGL--VASNCKSGSADSGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPG 1030
                +     ++S  +SG +  G   AP H P+   P+G    +PP   P    ++  P 
Sbjct: 239  SRSLSSSATPLSSPARSGPSARGTPRAPAH-PSQPKPKGLQALRPPQVTPPR--KDAAPA 295

Query: 1031 FKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNI--WEESSQAPGGPEL 1088
                  S+P A P     + S+ A    P +P  SS     A+ +     S  AP   + 
Sbjct: 296  L-GPLSSSPLATPSPSAALQSQ-APPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQT 353

Query: 1089 LPEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVAT 1148
            LP  P  A+P + ++ +  +     TH+ +                    P   L  +AT
Sbjct: 354  LPSPP--ATPPSQATTSLGSPTLQATHSFL--------------------PSPPLSPLAT 391

Query: 1149 SPAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGK 1208
             P      L LP    +    PPA PP +         LA+   +   A   H       
Sbjct: 392  PPPQAPPALALPPL--QAPPSPPASPPLSP--------LATPSPQAPNALAVHLLQAPFS 441

Query: 1209 PCPEDLEQTQ-----QRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQS 1263
            P P    Q         P+ P   P    P   + PP     S    S P+      P  
Sbjct: 442  PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA-SPPMSPSATPPPQ 500

Query: 1264 LTPLPAYPATQKVLQDPQSGEYFVFDLPLQV--KIKTFYDPETGKYVKVSIPSSEGASPE 1321
              P  A P  Q     PQ+        PLQ        +  +       S+P S  A+P 
Sbjct: 501  APPPLAAPPLQLAKPPPQAPPALATP-PLQALPSPPASFPGQAPFSPSASLPMSPLATPP 559

Query: 1322 PPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASAARA 1372
            P  P  LAAP +  P   P   T   P R       P     GPR + A A
Sbjct: 560  PQAPPVLAAPLLQVPPSPPASPTLQAPRR--PPTPGPDTSVSGPRLTLALA 608


>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis
           critical region 1 [Homo sapiens]
          Length = 1400

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 128/593 (21%), Positives = 202/593 (34%), Gaps = 126/593 (21%)

Query: 137 NKPVSKVSTLIKSFDRTESQRCESRPTASKPPALKNPPKFAPLPENSVNFCFDSAFLTVR 196
           +KP  K +   K+ D   S      P  S+              ENS N   D      R
Sbjct: 155 SKPTDKPTGNSKTIDHKSSTDNHEAPPTSE--------------ENSSNQGKDPMIRNQR 200

Query: 197 RV-PAEVSNTHQNSYQPGRKH--GEQESSKNPEMACHGSSSFLPAANDTATLCES----- 248
            V PA+ + TH+ S   G+KH     +S  N   +  G S+    ++ T    E      
Sbjct: 201 SVDPADSTTTHKES--AGKKHITPAPKSKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTL 258

Query: 249 -KFPSPHHKPVTGEPGRGKGTFLHSENSAFESWNAHQPKLLERKDTAGTVPESKAPKHY- 306
            K  +  HK  T     G         S  E   A      +   T GT  ES+  +   
Sbjct: 259 DKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYK---TTGTPEESEKTEDSR 315

Query: 307 ----GDTTLLREPCPPERTVSPCQVQASCSQEENRLAAGALSTSIPWGCRDPGAQVFAVE 362
                D  L +     + T+S  ++  S ++        A   + P       +     E
Sbjct: 316 TTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRTANENNTP-------SPAEPTE 368

Query: 363 GKAPSSQPDSQEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQFS 422
            +  ++  ++   PA+P            E+ + T  E T     GP      N +   +
Sbjct: 369 NRERTANENTTLSPAEPT-----------ENRERTANENTAPFPAGPT----ENREMTAN 413

Query: 423 ENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKE 482
           EN  L  P EP EH +   N +   +P  P++H   +A+      TPSP          E
Sbjct: 414 ENTTL-FPAEPTEHGERTANENTTPSPAEPTEHGERTANE---NTTPSP---------AE 460

Query: 483 PSECQSRDSYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGV 542
           P+E   R  + +                K+T SS+       E T     G++ P++N  
Sbjct: 461 PTEHGERTPFAND---------------KTTSSSA-------ESTE---HGERTPLANEN 495

Query: 543 ILPNGLE-----ESPPNELSKERPADDPTASHINPQKDPTADPSEPSADSYLTLSTAPTI 597
             P+  E     E   NE +   PA           +  T  P EP+ +   T +   T 
Sbjct: 496 TTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTP 555

Query: 598 AKAPFYVNGEAAERSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPG 657
           + A    NG   +R+ + N++           +S   +  EH  R  L+    N  P P 
Sbjct: 556 SPAEPTENG---QRTPFANEKT----------TSSSAEPTEHGERTPLANE--NTTPSPA 600

Query: 658 GATEKMKTHQLENGLSRSVSQETEPE----REAGLQNTHLNQKFFPGPLSPEE 706
             TE  +         R+ +++T P      E G +    N+K  P    P E
Sbjct: 601 EPTENRE---------RTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTE 644



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 94/437 (21%), Positives = 147/437 (33%), Gaps = 54/437 (12%)

Query: 196 RRVPAEVSNTHQNSYQPGRKHGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHH 255
           +R P     T  +S +P  +HGE+    N        S   P  N   T  E   PSP  
Sbjct: 565 QRTPFANEKTTSSSAEP-TEHGERTPLANENTT---PSPAEPTENRERTANEKTTPSPAE 620

Query: 256 KPVTGE--PGRGKGTFLHSENSAFESWNAHQPKLLERKDTAG----TVPESKAPKHYGDT 309
               G+  P   + T   + + A  + N  +      K T+     T  E + P    +T
Sbjct: 621 PTENGDRTPLANEKT---TPSLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENT 677

Query: 310 TLLREPCPP----ERTVSPCQVQASCSQEENR-LAAGALSTSIPWGCRDPGAQVFAVEGK 364
           T    P  P    ERT +     +     ENR + A   +T  P        +      K
Sbjct: 678 T--PSPAEPTENRERTANENTTPSPAGPTENREMTANEKTTLFP--AEPTENRERTANEK 733

Query: 365 APSSQPDSQEKPAQPPWRKPKTGKKGKESLQD-----TLEEKTQTNQRGPPLYTKHNPQE 419
             SS  +  E   + P+   KT     E  +         E T  +  GP        +E
Sbjct: 734 TTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAGPT-----ENRE 788

Query: 420 QFSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHA----LDSADSQPAERTPSPPGQL 475
           + +       P EP E+ +   N +   +P  P+++     L +  + P+   P+  G+ 
Sbjct: 789 RTANEKTTPFPAEPTENRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENGKR 848

Query: 476 NGY-QEKEPSECQSRDSYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGK 534
             +  EK  S       +  + P    N            +SSP      E T  +    
Sbjct: 849 TPFANEKTTSSSAEPTEHAERTPLANENT-----------TSSPA-----EPTENRERTA 892

Query: 535 QEPVSNGVILPNGLEESPPNELSKERPADDPTASHINPQKDPTADPSEPSADSYLTLSTA 594
            E  +     P    ES  NE +   PA+          ++ T  P+EP+    +T    
Sbjct: 893 NEKTTQFPAEPTENRESTANEKTTPFPAEPTENREWTANENTTLSPAEPTEHEEMTPLMV 952

Query: 595 PTIAKAPFYVNGEAAER 611
               +APF   G  AER
Sbjct: 953 DENLQAPFR-QGSCAER 968


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 247/1175 (21%), Positives = 399/1175 (33%), Gaps = 201/1175 (17%)

Query: 219  QESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENSAFE 278
            ++ SK P    H SSS  P         +    SP     +  P R          S FE
Sbjct: 824  KQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQR---------RSCFE 874

Query: 279  SWNAHQPKLLERKDTAGTVPESKAPKHYGDTTLLREPCPPERTVSPCQVQASCSQEENRL 338
            S  +  P+L  R  +  +   S  P+    T   + P    R+ SP     +      R 
Sbjct: 875  S--SPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSP---SRSSSPQPKVKAIISPRQRS 929

Query: 339  AAGALSTSIPW--------------GCRDPGAQVFAVEGKAPSSQPDSQEKPAQPPWRKP 384
             +G+ S S                  C +  +++      + SS PD++ KP  PP R+ 
Sbjct: 930  HSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPP-RQS 988

Query: 385  KTGKKGKESLQDTLEEKTQTNQRGPPLYTKHN--PQEQFSENNALDLP------------ 430
             +G     S+    + K QT   GP L    +  PQE+  ++     P            
Sbjct: 989  HSG-----SISPYPKVKAQT-PPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSS 1042

Query: 431  VEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPS-ECQSR 489
              P E Y   F +S L             + + P  R+ +   ++     + PS + +S+
Sbjct: 1043 TPPGESY---FGVSSL--------QLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQ 1091

Query: 490  DSYK-----SKAPSLLFNLKDVRKRVKSTYSSSPLLK--VLDEKTRGKVDGKQEPV--SN 540
             S K     S +P      +   ++ +  +S+SP+LK  +  E++R + D    P   SN
Sbjct: 1092 TSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSN 1151

Query: 541  GVILPNGLEESPPNELSKERPADDPTASHINPQKD-----PTADPSEPSADSYLTLSTAP 595
             ++  + LE +   E     P +D TAS    QKD     P  D  E S     TL T P
Sbjct: 1152 SLLGQSRLETAESKEKMALPPQEDATASPPR-QKDKFSPFPVQDRPESSLVFKDTLRTPP 1210

Query: 596  T----IAKAPFYVNGEAAERSSYENKEVEGELEMG--PAG--------------SSWCPD 635
                    +P      +A  +S +++E+   +E    PAG              +S    
Sbjct: 1211 RERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFES 1270

Query: 636  SREHRPRKHLSLRLCNRDPEPGGATEKMKTHQLENGLSRSVSQETEPEREAGLQNTHLNQ 695
            S E   R  +SL L     +   +   ++  ++ +  S        PE +  L N+ L +
Sbjct: 1271 SPEVEERPAVSLTL-----DQSQSQASLEAVEVPSMASSWGGPHFSPEHKE-LSNSPLRE 1324

Query: 696  KFF--------PGPLSPEEEDVFYSDSQSDFM----------PSLKGKAKFSTSSS-DQS 736
              F         GPL  E    F S+ + D            PSL  K + + SS    S
Sbjct: 1325 NSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSS 1384

Query: 737  FASFDDQQKMWFTENQR----------EDRRKDVSAGDSQKDEKENVMRKDELQYCALSN 786
              S D  +K   + NQ               ++ S+  S  + K+ + R    +  + S 
Sbjct: 1385 ELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRR--SRSG 1442

Query: 787  GHACLENRSQGEALQRERESVSGGRTRKASAEEANFRGSWIGENKGTTFSQAKDLTPSPS 846
                L + S   +    R S+SG             RG    E   +   +A   TP P 
Sbjct: 1443 SSPGLRDGSGTPS----RHSLSGSSPGMKDIPRTPSRGR--SECDSSPEPKALPQTPRPR 1496

Query: 847  SAS------NRHMLFTIKDNTLRATPVIKPIMLPLLRTMSLEDSLSSGHKEEELPRPEWG 900
            S S      N   L   ++ +   + V +     + RT   + S S   +E ++      
Sbjct: 1497 SRSPSSPELNNKCLTPQRERSGSESSVDQK---TVARTPLGQRSRSGSSQELDVKPSASP 1553

Query: 901  EDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAPKGNFPS 960
            ++             T TP   R    +  ++  ++   + S       S P  K    +
Sbjct: 1554 QERSESDSSPDSKAKTRTPLRQRS---RSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRA 1610

Query: 961  MPLVGEG-DRVKAPPDAAPGLVASNCKSGSADSGK----------LAAPWHIP------- 1002
             P    G D    P   AP  +    +SGS+  G+           ++P H P       
Sbjct: 1611 APRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARR 1670

Query: 1003 -TIALPEGDIEDQPPPWQ------PENCWEEQTPGFKSHFLSTPRA---GPPGRRLVPSE 1052
             + + PE   + + PP +      PE   + +         S+P      PP  R  PS 
Sbjct: 1671 GSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPS- 1729

Query: 1053 RANSPNPGSPGESSACSPAASNIWEESSQAPG-GPELLPEEPNQASPWASSSPARVTRRE 1111
              +SP P     SS    +AS+   +++   G  P   P    ++   +     R TRR 
Sbjct: 1730 -VSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRR 1788

Query: 1112 DLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELPAQLERTASK-- 1169
            D         GS        +  R+   R  +       +G   R     +  RT+S+  
Sbjct: 1789 D-------RSGSSQSTSRRRQRSRS---RSRVTRRRRGGSGYHSRSPARQESSRTSSRRR 1838

Query: 1170 --PPAVPPKTEKALR-RAKKLASKRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRE 1226
                  PP + K  R R      KR ++  +   H  S+   P         +     R 
Sbjct: 1839 RGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRR 1898

Query: 1227 RPRHNFPVV----RSLPPPVHRHSVSGFSEPVGRR 1257
            R R    V     RS   PV R      + PV RR
Sbjct: 1899 RSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRR 1933



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 82/353 (23%), Positives = 126/353 (35%), Gaps = 50/353 (14%)

Query: 1040 RAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPGGPELLPEEPNQASPW 1099
            R+  P RR   S R+ S  P   G S + +PA        + A          P +    
Sbjct: 636  RSRSPARR---SGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRS 692

Query: 1100 ASSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLEL 1159
             S +P R   R   + +LV  G S           RT   RG         +G+S   + 
Sbjct: 693  RSRTPRRGRSR---SRSLVRRGRSHS---------RTPQRRGR--------SGSSSERKN 732

Query: 1160 PAQLERTASKPPAVPP--KTEKALRRAKKLASKRRKTDQAQEKHGESQEGKPCPEDLEQT 1217
             ++  +  S+  + P   K+  + RR++ L+S R K               PCP+   QT
Sbjct: 733  KSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQT 792

Query: 1218 QQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGP-----QSLTPLP---- 1268
              R    R R   + P  +S  PP  R S S  S P  ++   P      S +P P    
Sbjct: 793  PPR----RSRSGSSQPKAKSRTPP--RRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKS 846

Query: 1269 AYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPSSEGASPEPPPPDAL 1328
              P  Q  +  PQ+ E  V       + ++ ++      +K   PS    S   PP    
Sbjct: 847  GTPPRQGSITSPQANEQSV-----TPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKS 901

Query: 1329 AAPYVLYPGFQPVPVTALMPL-----RCSSQLSAPTFLRQGPRASAARARTQS 1376
            + P    P     P   +  +     R  S  S+P+  R   R +  R+R+ S
Sbjct: 902  STPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVS 954



 Score = 34.7 bits (78), Expect = 0.68
 Identities = 56/245 (22%), Positives = 84/245 (34%), Gaps = 45/245 (18%)

Query: 1177 TEKALRRAKKLASKRRKTD----QAQEKHGESQEGKPCPEDLEQTQQRPLCPRERPRHNF 1232
            T K+ R++K    KR ++     +++  H  +        D  +++ R    +    H  
Sbjct: 233  TPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKT---HTT 289

Query: 1233 PVVRSLPPPVHRHSVSG---FSEP---VGRRPGGPQSLTPLPAYPATQKVLQDPQSGEYF 1286
             +    P P       G   FSEP     +RP  P++ T  P+ P   K           
Sbjct: 290  ALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDK----------- 338

Query: 1287 VFDLPLQVKIKTFYDPETGKYVKVSIPSSEGASPEPPPPDALAAPYVLYPGF-QPVPVTA 1345
              D   + K  T   P          P      PEPP P  L A    + G  QP+  T 
Sbjct: 339  --DKDKKEKSATRPSPS---------PERSSTGPEPPAPTPLLAE--RHGGSPQPLATTP 385

Query: 1346 LM--PLRCSSQLSAPTFLRQGPRASAARARTQSVHESGLQLDPGPHGDCTPHSAGQRPHG 1403
            L   P+   S+ S PT  R  P++     ++ S   S     P P        A   P  
Sbjct: 386  LSQEPVNPPSEAS-PTRDRSPPKSPEKLPQSSSSESS----PPSPQPTKVSRHASSSPES 440

Query: 1404 PPQSP 1408
            P  +P
Sbjct: 441  PKPAP 445



 Score = 34.3 bits (77), Expect = 0.89
 Identities = 191/1020 (18%), Positives = 331/1020 (32%), Gaps = 140/1020 (13%)

Query: 313  REPCPPER-TVSPCQVQASCSQEEN---RLAAGALSTSIPWGCRDPGAQVFAVEGKAPSS 368
            +E  P +R  V+     A  ++++N   R A G   + +     DP  Q  A E K P+ 
Sbjct: 108  KEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDP--QRRAREAKQPAP 165

Query: 369  QPDS------QEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQ-EQF 421
            +P        +   ++ P  K K  KK K+  + +     +  ++      KH  + E  
Sbjct: 166  EPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESK 225

Query: 422  SENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHA-----LDSADSQP------------ 464
               +    P    +  D     S+  TP   S+ A      DSA S              
Sbjct: 226  KRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAK 285

Query: 465  ------AERTPSPPGQLNGYQEKEPSECQSRDSYK-------SKAPSLLFNLKDVRKRVK 511
                  A R+PSP     G  +   SE  +  + +       +K PS  +  KD  K+ K
Sbjct: 286  THTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEK 345

Query: 512  STYSSSPLLK-------------VLDEKTRGKVDG------KQEPVSNGVILPNGLEESP 552
            S    SP  +             +L E+  G           QEPV+         + SP
Sbjct: 346  SATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSP 405

Query: 553  PNELSK---------ERPADDPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAKAPFY 603
            P    K           P+  PT    +    P +    P+  S+  +S++PT       
Sbjct: 406  PKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRS-- 463

Query: 604  VNGEAAERSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPGGATEKM 663
             +G A    S+ +             ++    SR   P K    R  +R P+   +    
Sbjct: 464  -HGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSR--SRSPQWRRSRSAQ 520

Query: 664  KTHQLENGLSRSVSQETEPEREAGLQNTHLNQKFFPGPLSPEEEDVFYSDSQS------D 717
            +  +  +   R  S+   P+R    ++ +  ++   G          +S S +       
Sbjct: 521  RWGRSRSPQRRGRSR--SPQRPGWSRSRNTQRR---GRSRSARRGRSHSRSPATRGRSRS 575

Query: 718  FMPSLKGKAKFSTSSSDQSFASFDDQQKMWFTENQREDRRKDVSAGDSQKDEKENVMRKD 777
              P+ +G+++  T +  +S +    +++       R  R +  +    +   +  V R+ 
Sbjct: 576  RTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRS 635

Query: 778  ELQYCALSNGHA-----CLENRSQGEALQRERESVS-----------------GGRTRKA 815
              +  A  +G +         RS+     R   S S                  GR+R  
Sbjct: 636  RSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSR 695

Query: 816  SAEEANFRGSWIGENKGTTFSQAKDLTPSPSSASNRHMLFTIKDNTLR--ATPVIKPIML 873
            +      R   +   +G + S+         S+S R           R  ++P +K   +
Sbjct: 696  TPRRGRSRSRSL-VRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRI 754

Query: 874  PLLRTMSLEDSLSSGHKEEELPRPEWGEDPGFC------APENQDILGTSTP---TNTRG 924
               R+ SL    S       L R   G  P  C       P  +   G+S P   + T  
Sbjct: 755  SSRRSRSLSSPRSKAKSRLSLRRSLSGSSP--CPKQKSQTPPRRSRSGSSQPKAKSRTPP 812

Query: 925  TRVKCMANEVMEDPGQGSSMARMEASQPAPKGNFPSMPLVGEGDRVKAPPDAAPGLVASN 984
             R +  ++   +   +  S     +S P PK    + P  G     +A   +      S 
Sbjct: 813  RRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSC 872

Query: 985  CKSGSADSGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPP 1044
             +S      K   P            ++   PP Q  +      P  K+      R+   
Sbjct: 873  FESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSG 932

Query: 1045 GRRLVPSERANSPNPGSPGESSACSPAASNI---WEESSQAPGGPELLPEEPNQASPWAS 1101
                 PS   +   P      S CS   S +   +  S  +    ++ PE P + S   S
Sbjct: 933  SSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGS 992

Query: 1102 SSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVA----TSPAGTS--- 1154
             SP    + +      +  G   P  +  ++D    S  GSL   A    ++P G S   
Sbjct: 993  ISPYPKVKAQTPPGPSL-SGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFG 1051

Query: 1155 -GRLELPAQLERTAS-KPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKPCPE 1212
               L+L  Q + +   +     P+  ++   +  L SK     Q   K G S+   P  E
Sbjct: 1052 VSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSK----SQTSPKGGRSRSSSPVTE 1107



 Score = 34.3 bits (77), Expect = 0.89
 Identities = 65/313 (20%), Positives = 109/313 (34%), Gaps = 47/313 (15%)

Query: 946  RMEASQPAPKGN----FPSMPLVGEGDRVKAPPDAAPGLVASNCKSGSADS------GKL 995
            R  ++ PAPK        S       D  ++   +A     +   +G + S      G+ 
Sbjct: 247  RSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEG 306

Query: 996  AAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERAN 1055
             AP+  P     +     +    QP + +E++    K    + P   P      P   A 
Sbjct: 307  DAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAP 366

Query: 1056 SP-----NPGSPGESSACSPAASNIWEESSQA--------PGGPELLPEEPNQASPWASS 1102
            +P     + GSP +  A +P +       S+A        P  PE LP+  +  S   S 
Sbjct: 367  TPLLAERHGGSP-QPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSP 425

Query: 1103 SPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELPAQ 1162
             P +V+R     HA             S E  +     GS  ++++SP  +  R    A+
Sbjct: 426  QPTKVSR-----HA-----------SSSPESPKPAPAPGSHREISSSPT-SKNRSHGRAK 468

Query: 1163 LERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKPCPEDLEQTQQ--R 1220
             +++ S  P+          R+   A + R   +   K G S+   P        Q+  R
Sbjct: 469  RDKSHSHTPS----RRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGR 524

Query: 1221 PLCPRERPRHNFP 1233
               P+ R R   P
Sbjct: 525  SRSPQRRGRSRSP 537



 Score = 30.8 bits (68), Expect = 9.8
 Identities = 44/217 (20%), Positives = 70/217 (32%), Gaps = 37/217 (17%)

Query: 894  LPRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPA 953
            +P  + GE P     +    L    P   R +                SS +   +S  +
Sbjct: 2501 VPHSDVGEPPASTGAQQPSALAALQPAKERRSS---------SSSSSSSSSSSSSSSSSS 2551

Query: 954  PKGNFPSMPLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIPTIALPEGDIED 1013
               +  S     EG  +   P+ A   V S                  PT A  E   E 
Sbjct: 2552 SSSSSGSSSSDSEGSSLPVQPEVALKRVPS------------------PTPAPKEAVREG 2593

Query: 1014 QPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAAS 1073
            +PP         E TP  +    S+  +         S  ++S +  S   SS+ S ++S
Sbjct: 2594 RPP---------EPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2644

Query: 1074 NIWEESSQAPGGPELLPEEPNQASPWASSSPARVTRR 1110
            +    S   PG P+ LP+  +   P      +R  R+
Sbjct: 2645 SSSSPSPAKPG-PQALPKPASPKKPPPGERRSRSPRK 2680


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
          Length = 816

 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 116/493 (23%), Positives = 152/493 (30%), Gaps = 48/493 (9%)

Query: 919  PTNTRGTRVKCMANEVMEDPGQGSSMARMEAS-QPAPKGN----FPSMPLVGEGDRVKAP 973
            P + RG R     N     PG  SS  R   + +P P G       +   V  G   +AP
Sbjct: 86   PASGRGERAPPAKNT---SPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAP 142

Query: 974  PDAAPGLVASNCKSGSADSGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFKS 1033
              +A    A    SG        A       A  E  +    P  +P    E       S
Sbjct: 143  KRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSS 202

Query: 1034 HFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPGGPELLPEEP 1093
                +     P  R  PS       P S   SS+ +P +S     S  +  G    P  P
Sbjct: 203  ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA--RSGPSARGTPRAPAHP 260

Query: 1094 NQASPWASSS--PARVTR-REDLTHAL--------VWEGGSDPLLELSAEDLRTL-SPRG 1141
            +Q  P    +  P +VT  R+D   AL             S P    +   L+TL SP  
Sbjct: 261  SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPA 320

Query: 1142 SLLDVATSPAGT---------------SGRLELPAQLERTASKPPAVPPKTEKALRRAKK 1186
            +    AT+  G+               S     P Q     + PP   P +  A      
Sbjct: 321  TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSP 380

Query: 1187 LASKRRKTDQAQEKHGESQEGKPCPEDLEQTQ-----QRPLCPRERPRHNFPVVRSLPPP 1241
            LA+   +   A   H       P P    Q         P+ P   P    P   + PP 
Sbjct: 381  LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL 440

Query: 1242 VHRHSVSGFSEPVGRRPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQV--KIKTF 1299
                S    S P+      P    P  A P  Q     PQ+        PLQ        
Sbjct: 441  QVPPSPPA-SPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP-PLQALPSPPAS 498

Query: 1300 YDPETGKYVKVSIPSSEGASPEPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPT 1359
            +  +       S+P S  A+P P  P  LAAP +  P   P   T   P R       P 
Sbjct: 499  FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR--PPTPGPD 556

Query: 1360 FLRQGPRASAARA 1372
                GPR + A A
Sbjct: 557  TSVSGPRLTLALA 569


>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
          Length = 1682

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 96/360 (26%), Positives = 120/360 (33%), Gaps = 75/360 (20%)

Query: 1041 AGPPGRRLVPSERANSPNPGSPG-ESSACSPAA----SNIWEESSQ-------------- 1081
            A PPG RLVP+     P P  PG ES  C PA     S++ E   Q              
Sbjct: 322  AHPPGHRLVPAAPPG-PGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAATT 380

Query: 1082 --APGGPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGGSD----PLLELSAEDLR 1135
               P  P   P  P   +  +SSS +    R    +  +   G+D    P LE+S     
Sbjct: 381  ACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGI--PGADHYQTPALEVSHHGRL 438

Query: 1136 TLSPRGSLLDVATSPAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTD 1195
              S   S      +PA T   L LP       S PP  PP   + LR     A  +    
Sbjct: 439  GPSAHSSRKPFLGAPAATP-HLSLPPG----PSSPP--PPPCPRLLRPPPPPAWLKGPAC 491

Query: 1196 QAQEKHGE-------SQEGKPCPEDLEQTQQRPLCPRER----PRHNFPV------VRSL 1238
            +A  + GE         EG P P         PL  RE     P   F V          
Sbjct: 492  RAAREDGEILEELFFGTEGPPRPAP------PPLPHREGFLGPPASRFSVGTQDSHTPPT 545

Query: 1239 PPPVHRHSVSGFSEPVGRRPGGPQSLTPLP-------AYPATQKVLQDPQSGEYFVFDLP 1291
            PP     S +  S      P GP S  P P         P      Q+PQ        L 
Sbjct: 546  PPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLA 605

Query: 1292 L---------QVKIKTFYDPETGKYVKVSIPSSEGASPEPPPPDALAAPYVLYPGFQPVP 1342
            L         Q    +F  PE+ +  +VS P +    P PPP     AP  + PG   +P
Sbjct: 606  LPPAPPSSCHQNTSGSFRRPESPR-PRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELP 664


>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
            [Homo sapiens]
          Length = 1412

 Score = 45.4 bits (106), Expect = 4e-04
 Identities = 103/457 (22%), Positives = 153/457 (33%), Gaps = 91/457 (19%)

Query: 884  SLSSGHKEEELPRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSS 943
            S S   +EEE    E  +     A  N  +LG   P++     +K  A    E  G+  +
Sbjct: 83   STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS-----MKEKAKAETEKAGKTGN 137

Query: 944  MARMEASQPAPK-GNFPSMPLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIP 1002
                  S P P  G   +  L G+  R  A P A   LV+   + GS  +   AA   + 
Sbjct: 138  ------SMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMV 191

Query: 1003 TIALPEGDIEDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSP 1062
            +    +   ED                   S    T        +++    A++P  G+P
Sbjct: 192  SAGQADSSSEDT-----------------SSSSDETDVEVKASEKILQVRAASAPAKGTP 234

Query: 1063 GESSACSPAASNIWEESSQAPGGPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGG 1122
            G+ +  +P        +SQ   G    PEE +++S   SS     T              
Sbjct: 235  GKGATPAP-PGKAGAVASQTKAGK---PEEDSESSSEESSDSEEET------------PA 278

Query: 1123 SDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELPAQLERTASKPPAVPPKTEKALR 1182
            +  LL+  A      S + S +  A++PA  S R              PA P KT  A+ 
Sbjct: 279  AKALLQAKA------SGKTSQVGAASAPAKESPR----------KGAAPAPPGKTGPAV- 321

Query: 1183 RAKKLASKRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPV 1242
             AK  A KR +  Q+  +  +S+E  P               + +P    P VR+   P 
Sbjct: 322  -AKAQAGKREEDSQSSSEESDSEEEAPA--------------QAKPSGKAPQVRAASAPA 366

Query: 1243 HRHSVSGFSEPVGRRPGGPQSLTPLPAYPATQKVLQDPQ-SGEYFVFDLPLQVKIKTFYD 1301
                    S   G  P  P+   P  A     K  +D + S E    D      +     
Sbjct: 367  KE------SPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQV 420

Query: 1302 PETGKYVKVSI-------PSSEGASPEPPPPDALAAP 1331
               GK  +V         P  +GA P PP     A P
Sbjct: 421  KPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATP 457


>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
            sapiens]
          Length = 1411

 Score = 45.4 bits (106), Expect = 4e-04
 Identities = 103/457 (22%), Positives = 153/457 (33%), Gaps = 91/457 (19%)

Query: 884  SLSSGHKEEELPRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSS 943
            S S   +EEE    E  +     A  N  +LG   P++     +K  A    E  G+  +
Sbjct: 83   STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS-----MKEKAKAETEKAGKTGN 137

Query: 944  MARMEASQPAPK-GNFPSMPLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIP 1002
                  S P P  G   +  L G+  R  A P A   LV+   + GS  +   AA   + 
Sbjct: 138  ------SMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMV 191

Query: 1003 TIALPEGDIEDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSP 1062
            +    +   ED                   S    T        +++    A++P  G+P
Sbjct: 192  SAGQADSSSEDT-----------------SSSSDETDVEVKASEKILQVRAASAPAKGTP 234

Query: 1063 GESSACSPAASNIWEESSQAPGGPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGG 1122
            G+ +  +P        +SQ   G    PEE +++S   SS     T              
Sbjct: 235  GKGATPAP-PGKAGAVASQTKAGK---PEEDSESSSEESSDSEEET------------PA 278

Query: 1123 SDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELPAQLERTASKPPAVPPKTEKALR 1182
            +  LL+  A      S + S +  A++PA  S R              PA P KT  A+ 
Sbjct: 279  AKALLQAKA------SGKTSQVGAASAPAKESPR----------KGAAPAPPGKTGPAV- 321

Query: 1183 RAKKLASKRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPV 1242
             AK  A KR +  Q+  +  +S+E  P               + +P    P VR+   P 
Sbjct: 322  -AKAQAGKREEDSQSSSEESDSEEEAPA--------------QAKPSGKAPQVRAASAPA 366

Query: 1243 HRHSVSGFSEPVGRRPGGPQSLTPLPAYPATQKVLQDPQ-SGEYFVFDLPLQVKIKTFYD 1301
                    S   G  P  P+   P  A     K  +D + S E    D      +     
Sbjct: 367  KE------SPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQV 420

Query: 1302 PETGKYVKVSI-------PSSEGASPEPPPPDALAAP 1331
               GK  +V         P  +GA P PP     A P
Sbjct: 421  KPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATP 457


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 128/542 (23%), Positives = 177/542 (32%), Gaps = 70/542 (12%)

Query: 903  PGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQ-GSSMARMEASQPAPKGNFPSM 961
            P  C  E+    G S   +++GT        + + P   G S++      P  KG+    
Sbjct: 767  PKECPTEDS---GASATASSKGT-----LTYLADSPSPLGVSVSPQTKRPPTKKGSAGPD 818

Query: 962  PLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIPTIALPEG-DIEDQPPPWQP 1020
              +G      +P +A+     S    GS DS    A  H PT   P+G        P  P
Sbjct: 819  TPIGNLSSPVSPVEASFLPENSLSFQGSKDS---PATTHSPTPPSPKGAPTPSAVTPLSP 875

Query: 1021 ENCW--EEQTPGFKSHFLSTPRAGP--PGRRLVPSERANSPNPGSPGESSACSPAASNIW 1076
            +      ++TP      L  P+ GP  P  +  P+    S +P    + +  +PA   I 
Sbjct: 876  KGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSP----KKARATPAPKGIP 931

Query: 1077 EESSQ--APGGPELLPEEPN--QASP---WASSSPARVTRREDLTHALVWEGGSDPLLEL 1129
               S   AP  P   P  P    A+P   WA + PA          A     G+      
Sbjct: 932  ASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAA 991

Query: 1130 SAEDLR----TLSPRGSLLDVATSPAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAK 1185
            +    +    T SP+G+    A +P    G         + AS PPA  P + K    A 
Sbjct: 992  TPPSPKGGPATPSPKGAPTPPAVTPPSPKGS-PAATPFPKGASTPPAATPPSPKGSPAAT 1050

Query: 1186 KLASKRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLC----PRERPRHNFPVVRSLPPP 1241
             L      T  A      S +G P    L+     P      P+  P    P    +PP 
Sbjct: 1051 PLPKGAPTTPAATLP---SPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPA 1107

Query: 1242 VHRHSVSG-FSEPVGRRPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFY 1300
                S  G  + P  +  G P +    P  P        P+         P   K     
Sbjct: 1108 ATPPSPKGGLATPPHK--GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT 1165

Query: 1301 DPETGKYVKVSIPSSEGASPEPPPPDALAAPYVLYPGFQPVPVTALMP-----LRCSSQL 1355
             P  G       P++  A+P P P   LA P    P   P    A  P     L   S  
Sbjct: 1166 PPPKGA------PTTPAATP-PSPKGGLATPS---PKGAPTTPAATPPSPKGGLATPSPK 1215

Query: 1356 SAPTFLRQGPRASAARARTQSVHESGLQLDPGPHG-DCTPHSAGQRPHGPPQSPGEEGVE 1414
             APT            A T    + GL   P P G   TP +    P G P +P  +G  
Sbjct: 1216 GAPT----------TPAATPPSPKGGLAT-PSPKGAPTTPAATPPSPKGGPATPPPKGAP 1264

Query: 1415 AP 1416
             P
Sbjct: 1265 TP 1266



 Score = 40.8 bits (94), Expect = 0.009
 Identities = 76/355 (21%), Positives = 112/355 (31%), Gaps = 49/355 (13%)

Query: 949  ASQPAPKGNFPSMPLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIPTIALPE 1008
            A+ P+PKG   + P  G      A P +  G +A+    G+  +     P        P+
Sbjct: 1108 ATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP-------SPK 1160

Query: 1009 GDIEDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPG--SPGESS 1066
            G +   PP   P       TP      L+TP   P G    P+    SP  G  +P    
Sbjct: 1161 GGLATPPPKGAPTT--PAATPPSPKGGLATP--SPKGAPTTPAATPPSPKGGLATPSPKG 1216

Query: 1067 A-CSPAASNIWEESSQAPGGPELLPEEPNQASPWASSSPARVTRREDLTHALV------- 1118
            A  +PAA+    +   A   P+  P  P    P     PA    +   T           
Sbjct: 1217 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKG 1276

Query: 1119 ------WEGGSDPLLELSAEDL---RTLSPRGSLLDVATSPAGTSGRLELPAQLERTASK 1169
                   +G  +P +           T  P+G+    A +P    G    P    + A  
Sbjct: 1277 GLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPP--PKGAPT 1334

Query: 1170 PPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRERPR 1229
            PPAV P + K              T         S+ G   P     +++ P  P   P 
Sbjct: 1335 PPAVTPPSPKG-------------TPTLPATTPSSKGGPTTP----SSKEGPTPPAATPS 1377

Query: 1230 HNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPAYPATQKVLQDPQSGE 1284
            H      + P P    ++             P S    PA P T++    P  G+
Sbjct: 1378 HKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGD 1432



 Score = 38.1 bits (87), Expect = 0.061
 Identities = 90/404 (22%), Positives = 135/404 (33%), Gaps = 50/404 (12%)

Query: 949  ASQPAPKGNFPSMPLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIPTIALPE 1008
            A+ P+PKG   +    G      A P +  G +A+    G+  +     P        P+
Sbjct: 1200 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP-------SPK 1252

Query: 1009 GDIEDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLV--PSER---ANSPNPGSPG 1063
            G     PP   P        P  K    + P  G P   +V  PS +   A SP  G+P 
Sbjct: 1253 GGPATPPPKGAPTPP-AATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPT 1311

Query: 1064 ESSAC--SPAASNIWEESSQAPGGPELLPEEPNQASPWASSSPARVTRREDLTHALVWEG 1121
              +A   SP  S        AP  P + P  P       +++P   + +   T     EG
Sbjct: 1312 PPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTP---SSKGGPTTPSSKEG 1368

Query: 1122 GSDPLLELSAEDLRTLSP----RGSLLDVATSPAGTSGRLELPAQLERTASKPPAVPPKT 1177
             + P    S +    ++P    RG  +    SP G       PA +  +  K PA P   
Sbjct: 1369 PTPPAATPSHKGGPAMTPPSPKRGPAI---PSPKGDP---TSPAVIPLSPKKAPATPVTR 1422

Query: 1178 EKALRRAKKLASKRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRERPRHNFPVVRS 1237
            E A   +K   +    T  + +K   +   K  P     ++  P  P   P    P  + 
Sbjct: 1423 EGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPA-TPSSKGDPTLPAVTP----PSPKE 1477

Query: 1238 LPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPA--------YPATQKVLQDP--QSGEYFV 1287
              PP  +   +  S         P     LPA         PAT    +DP   +     
Sbjct: 1478 --PPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLS 1535

Query: 1288 FDLPLQVKIKTFYDPETGKYVKVSIPSSEGASPEPPPPDALAAP 1331
               P  +  K    P       +++PS +     P P +A A P
Sbjct: 1536 KKTPATLAPKEALIPPA-----MTVPSPKKTPAIPTPKEAPATP 1574



 Score = 33.5 bits (75), Expect = 1.5
 Identities = 96/489 (19%), Positives = 155/489 (31%), Gaps = 49/489 (10%)

Query: 952  PAPKGNFPSMPLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIPTIALPEGDI 1011
            P+PKG   + P  G      A P +  G   +    G+     +  P    T  LP    
Sbjct: 1295 PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTP 1354

Query: 1012 EDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPG--ESSACS 1069
              +  P  P +      P         P   PP  +  P+  +   +P SP     S   
Sbjct: 1355 SSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKK 1414

Query: 1070 PAASNIWEESSQAPGGPELLP---------EEPNQASPWASSSPARVTRREDLTHALVWE 1120
              A+ +  E +  P   +L P         + P  ++P     PA  + + D T   V  
Sbjct: 1415 APATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAP--KGGPATPSSKGDPTLPAV-- 1470

Query: 1121 GGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELPAQLERTASKPPAVPPKTEKA 1180
                P         + ++   S      +PA   G   LPA +  +  + PA P      
Sbjct: 1471 ---TPPSPKEPPAPKQVATSSSPKKAPATPA-PMGAPTLPAVIPSSPKEVPATPSSRRDP 1526

Query: 1181 LRRAKKLASKRRKTDQA-QEKHGESQEGKPCPED---LEQTQQRPLCPRERPRHNFPVV- 1235
            +     L SK+     A +E         P P+    +   ++ P  P  +   + P V 
Sbjct: 1527 IAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVT 1586

Query: 1236 ----RSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPL-----PAYPATQKVLQDPQSGEYF 1286
                +  P P         + P  +    P ++TP      PA PA +     P      
Sbjct: 1587 PSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSS 1646

Query: 1287 VFDLPLQVKIKTFYDPETGKYVKVSIPSSEG--------ASPEPPPPDALAAPYVLYPGF 1338
            + D P      T     T       +P+ +G         +P P     + AP     G 
Sbjct: 1647 LKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAP--TRKGP 1704

Query: 1339 QPVPVTALMPLRCSSQLSAPTFLRQGPRASAARARTQSVHESGLQLDPGPHGDCTPHSAG 1398
            Q    +A  P  C    +      +GP ++ A A    V +   +   G     +P    
Sbjct: 1705 QTKKSSATSPPICPDPSAKNG--SKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSP---- 1758

Query: 1399 QRPHGPPQS 1407
            + P  PP+S
Sbjct: 1759 KGPLAPPES 1767


>gi|33667044 ABI gene family, member 3 (NESH) binding protein [Homo
            sapiens]
          Length = 1075

 Score = 43.9 bits (102), Expect = 0.001
 Identities = 71/332 (21%), Positives = 110/332 (33%), Gaps = 67/332 (20%)

Query: 1131 AEDLRTLSPRGSLLDVATSPAGTSGRLELPAQLERTASKP-PAVPPKTEKALRRAKK-LA 1188
            +ED + L P+ +  DV +SP  TS   E+      T+ +   ++PPKT + L + +  LA
Sbjct: 376  SEDSKVLQPQTATYDVFSSPT-TSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLA 434

Query: 1189 SKRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRERPRHN---------------FP 1233
                     + +   S E +P     +QT   P  P+ RPR                  P
Sbjct: 435  PSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITP 494

Query: 1234 VVRSLPPPVHRHSVSGFSEPVGRRPGGPQS---------------------LTPLPAYPA 1272
             +   P P       G ++ +  +P  P S                      +P P  P 
Sbjct: 495  KISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQ 554

Query: 1273 TQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSI-------PSSEGASPEPPPP 1325
            TQ V + PQ          +  K KT   PE                P  E +  EP P 
Sbjct: 555  TQPVPKVPQR---------VTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPL 605

Query: 1326 DALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASAARARTQSVHESGLQLD 1385
            +    P++      P        L  + Q +   F  + PR +     TQ+ H     + 
Sbjct: 606  ETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVR 665

Query: 1386 PGPHGDCTPHSAGQRPH---GPPQSPGEEGVE 1414
            P             +PH   G  Q+P   G +
Sbjct: 666  P---------RTSDKPHIRPGVKQAPRPSGAD 688


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 44/142 (30%), Positives = 58/142 (40%), Gaps = 20/142 (14%)

Query: 1160 PAQLERTASKPPA-VPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKPCPED----- 1213
            PA++  T  KP + +PP      R+   L  + R    +QE  G+   G   P       
Sbjct: 668  PAEVGPTTEKPSSHLPPTPRATTRQDSSLGGRARHMSSSQELLGDGPPGPSSPMSRSQEY 727

Query: 1214 -LEQTQQRPLCPRE-RP-RHNFPVVRSLPPPVHRH-------SVSGFS---EPVGRRPGG 1260
             L++       PRE RP RH   + R+  PPV            S F+    P   RPG 
Sbjct: 728  LLDEGPAPGTPPREARPGRHGHSIKRASVPPVPGKPRQVLPPGTSHFTPPQTPTKTRPGS 787

Query: 1261 PQSL-TPLPAYPATQKVLQDPQ 1281
            PQ+L  P    PAT KV   PQ
Sbjct: 788  PQALGGPHGPAPATAKVKPTPQ 809



 Score = 40.4 bits (93), Expect = 0.012
 Identities = 151/614 (24%), Positives = 201/614 (32%), Gaps = 135/614 (21%)

Query: 864  ATPVIKP---IMLPLLRTMS---LEDSLSSGHKEEELPRPEWGEDPGFCAPENQDILGTS 917
            AT  +KP   ++ P  R MS   L  S +       LP+P  GE  G  AP      G +
Sbjct: 800  ATAKVKPTPQLLPPTERPMSPRSLPQSPTHRGFAYVLPQPVEGE-VGPAAP------GPA 852

Query: 918  TPTNTRGTRVKCMANEVMEDPGQ----GSSMARMEASQPAPKGNFPSMPL---------- 963
             P         C+  E   +PG+      S+ R  AS   P+ +   +P           
Sbjct: 853  PPPVPTAVPTLCLPPEADAEPGRPKKRAHSLNRYAASDSEPERDELLVPAAAGPYATVQR 912

Query: 964  -VGEGDRVKAPPDAAPGLVASNCKS-GSADSGKLAAPWHIPTIALPEGDIEDQP-PPWQP 1020
             VG    V+AP  A   +  S   +      G    P    + AL   ++ D+P P  +P
Sbjct: 913  RVGRSHSVRAPAGADKNVNRSQSFAVRPRKKGPPPPPPKRSSSALASANLADEPVPDAEP 972

Query: 1021 ENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPG--ESSACSPAASNIWEE 1078
            E+       G         RA         S+ A S + GS G  +S A     S+I   
Sbjct: 973  ED-------GLLGVRAQCRRA---------SDLAGSVDTGSAGSVKSIAAMLELSSIGGG 1016

Query: 1079 SSQAPGGPELLPEEPNQASPWASSSPARV-TRREDLTHALVWEGGSDPLLELSAEDLRTL 1137
               A   PE  P  P  ASP     P RV T    + H      G + +        RTL
Sbjct: 1017 GRAARRPPEGHPT-PRPASP----EPGRVATVLASVKHKEAIGPGGEVV-----NRRRTL 1066

Query: 1138 S-PRGSLLDVATSPAGTSG-------------RLELPAQLERTASKPPAVPPKTEKALRR 1183
            S P   LL  A    G S              R   P++ E     PP    +    L+R
Sbjct: 1067 SGPVTGLLATARRGPGESADPGPFVEDGTGRQRPRGPSKGEAGVEGPPLAKVEASATLKR 1126

Query: 1184 AKKLASKRRK----------TDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRERPRHNFP 1233
              +    +++          T + + K  E + G   P  L          R RP     
Sbjct: 1127 RIRAKQNQQENVKFILTESDTVKRRPKAKEREAGPEPPPPLSVYHNGTGTVRRRPASEQA 1186

Query: 1234 VVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQ 1293
                LPPP           P    P  P  L  LP  P  +   + P         +  Q
Sbjct: 1187 GPPELPPP----------PPPAEPP--PTDLAHLPPLPPPEGEARKPAKPPVSPKPVLTQ 1234

Query: 1294 VKIKTFYDPE-TGKYVKVSIPSSEGA----------SPEPPPPDALAAPYVLYPGFQPVP 1342
               K    P  T K V +  P S             SP+PPPP    AP       +PV 
Sbjct: 1235 PVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPP--TAP-------KPVK 1285

Query: 1343 VTALMPLRCSSQLSAPTFLRQGPRASAARARTQSVHESGLQLDPGPHGDCTPHSAGQRPH 1402
              A +P   +    AP+  RQ P A              L   PG     TP S G  P 
Sbjct: 1286 AVAGLPSGSAGPSPAPSPARQPPAA--------------LAKPPG-----TPPSLGASPA 1326

Query: 1403 GPPQSPGEEGVEAP 1416
             PP SPG   +  P
Sbjct: 1327 KPP-SPGAPALHVP 1339


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 43.1 bits (100), Expect = 0.002
 Identities = 72/323 (22%), Positives = 113/323 (34%), Gaps = 41/323 (12%)

Query: 893  ELPRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQP 952
            E P P   E+P   AP        +TP     T  K  A    ++P   +     E +  
Sbjct: 520  EEPTPTTPEEP---APTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK---ETAPT 573

Query: 953  APKGNFPSMPLVGEGDRVK--APPDAAPGLV----ASNCKSGSADSGKLAAPWHIPTIAL 1006
             PKG  P+          K  AP + AP       ++ C   +  + K  AP    T   
Sbjct: 574  TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP---TTPKE 630

Query: 1007 PEGDIEDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVP-------SERANSPNP 1059
            P      +P P  P+          K    +TP+   P + L P       S  ++ P P
Sbjct: 631  PAPTTPKEPAPTTPKGT---APTTLKEPAPTTPKKPAP-KELAPTTTKGPTSTTSDKPAP 686

Query: 1060 GSPGESSACSPAASNIWEESSQAPGGPELLPEEPNQAS-PWASSSPARVTRREDLTHALV 1118
             +P E++  +P           AP  PE  P   ++ S P  +  P  + +  D      
Sbjct: 687  TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPD------ 740

Query: 1119 WEGGSDPLLELSAEDLRTL---SPRGSLLDVATSPAGTSGRLELPAQLERTASKPPAVPP 1175
                 +   ELSAE        SP+   +    +PA T   +   A+ + T       P 
Sbjct: 741  -----ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE 795

Query: 1176 KTEKALRRAKKLASKRRKTDQAQ 1198
             T  A +  K+ A+   KT +++
Sbjct: 796  TTTAAPKMTKETATTTEKTTESK 818



 Score = 40.8 bits (94), Expect = 0.009
 Identities = 83/407 (20%), Positives = 128/407 (31%), Gaps = 53/407 (13%)

Query: 209 SYQPGRKHGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGT 268
           S++ GR+       K  +  C    SF     D       K P+P   PV  E G G   
Sbjct: 36  SFERGRECDCDAQCKKYDKCCPDYESFCAEVKDNKKNRTKKKPTPK-PPVVDEAGSG--- 91

Query: 269 FLHSENSAFESWNAHQPKLLERKDTAGTVPESKAPKHYGDTTLLREPCPPERTVSPCQVQ 328
                              L+  D   T P++   +H   +T      P   T  P   +
Sbjct: 92  -------------------LDNGDFKVTTPDTSTTQHNKVST-----SPKITTAKPINPR 127

Query: 329 ASCSQEENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPSSQPDSQEKP--AQPPWRKPKT 386
            S     +     +L+ +     ++   +          +  D +EK   A+      KT
Sbjct: 128 PSLPPNSDTSKETSLTVN-----KETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 182

Query: 387 GKKGKESLQDTLEE---KTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNI 443
             K        L +   K +T  +GP L T   P     +  A   P EP     P    
Sbjct: 183 SAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT----PTTIK 238

Query: 444 SKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNL 503
           S   TP  P+     SA + P E  P+   +      KEP+   +++   +   S     
Sbjct: 239 SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 298

Query: 504 KD----VRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESPPNELSKE 559
           K+      K+   T    P      E T      K+   +     P   +E  P    K 
Sbjct: 299 KEPAPTTPKKPAPTTPKEPAPTTPKEPT--PTTPKEPAPTTKEPAPTTPKEPAPTAPKKP 356

Query: 560 RPADDPTASHINPQKD-PTA----DPSEPSADSYLTLSTAPTIAKAP 601
            P      +   P++  PT      P+ P   +  T  +APT  K P
Sbjct: 357 APTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 403



 Score = 38.5 bits (88), Expect = 0.047
 Identities = 69/347 (19%), Positives = 111/347 (31%), Gaps = 23/347 (6%)

Query: 1025 EEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPG 1084
            +E TP       +TP+   P            P P +  E +  +P           AP 
Sbjct: 230  KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 289

Query: 1085 GPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLEL-SAEDLRTLSPRGSL 1143
              +  P  P + +P     PA  T +E           + P     + ++    +P+   
Sbjct: 290  TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 349

Query: 1144 LDVATSPAGTSGRLELPAQLER---TASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEK 1200
                  PA T+ +   P   +    T +K P+     E A    K   +  ++      K
Sbjct: 350  PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 409

Query: 1201 HGESQEGKPCPEDLEQTQQRPLCPRE----RPRHNFPVVRSLPPPV--HRHSVSGFSEPV 1254
               +   +P P   +  +  P  P+E     P+   P     P P      + +   +P 
Sbjct: 410  SAPTTPKEPSPTTTK--EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 467

Query: 1255 GRRPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPS 1314
               P  P   TP    P T K L  P + E      P +        P T + +  + P 
Sbjct: 468  PTTPKEPAPTTPKETAPTTPKKL-TPTTPEKLAPTTPEKPA------PTTPEELAPTTP- 519

Query: 1315 SEGASPEPPPPDALAAPYVLYPGF--QPVPVTALMPLRCSSQLSAPT 1359
             E  +P  P   A   P    P    +P P T   P   + +  APT
Sbjct: 520  -EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 565



 Score = 38.1 bits (87), Expect = 0.061
 Identities = 106/545 (19%), Positives = 168/545 (30%), Gaps = 51/545 (9%)

Query: 96  AATFQQLPKYVQGEEKYPKTSPPPTPVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTES 155
           A T  + P     +E  P T   PTP   +   P +   +   P                
Sbjct: 302 APTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK--------------- 346

Query: 156 QRCESRPTASKPPALKNPPKFAPLPENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRK 215
              E  PTA K PA   P + AP          + A  T +    E S T      P   
Sbjct: 347 ---EPAPTAPKKPAPTTPKEPAPTTPK------EPAPTTTK----EPSPTTPKEPAPTTT 393

Query: 216 HGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENS 275
                ++K P      S+   P    + T  +   P+   +P    P +   T       
Sbjct: 394 KSAPTTTKEPAPTTTKSAPTTP-KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 452

Query: 276 AFESWNAHQPKLLERKDTAGTVPESKA---PKHYGDTTLLR-EPCPPERTVSPCQVQASC 331
                   +P     K  A T P+  A   PK    TT  +  P  PE+ ++P   +   
Sbjct: 453 T----TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK-LAPTTPEKPA 507

Query: 332 SQEENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPSSQPDSQEKPAQPPWRKPKTGKKGK 391
                 LA        P    +P            ++ P++ ++PA P   K       K
Sbjct: 508 PTTPEELAPTTPEEPTPTTPEEPAPTT------PKAAAPNTPKEPA-PTTPKEPAPTTPK 560

Query: 392 ESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISKLLTPII 451
           E    T +E   T  +G    T   P     +  A    + P    +P         P  
Sbjct: 561 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKEPTSTTCDKPAPTT 619

Query: 452 PSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLKDVRKRVK 511
           P K    +   +PA  TP  P      +   P+  +       K P+         K   
Sbjct: 620 P-KGTAPTTPKEPAPTTPKEPAPTTP-KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPT 677

Query: 512 STYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESPP--NELSKERPADDPTASH 569
           ST S  P      ++T      +  P +     P   E  PP  +E+S      +PT  H
Sbjct: 678 STTSDKP-APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 736

Query: 570 INPQKDPTADPSEPSADSYLTLSTAPTIAKAPFYVNGEAAERSSYENKEVEGELEMGPAG 629
            +P +      +EP+  +       P +         +    ++ ++K  E +L   P  
Sbjct: 737 KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPET 796

Query: 630 SSWCP 634
           ++  P
Sbjct: 797 TTAAP 801



 Score = 38.1 bits (87), Expect = 0.061
 Identities = 107/521 (20%), Positives = 157/521 (30%), Gaps = 73/521 (14%)

Query: 96  AATFQQLPKYVQGEEKYPKTSPPPTPVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTES 155
           A T  + P     +E  P T   P P   +   P +    +        T  K    T +
Sbjct: 349 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 408

Query: 156 QRC-----ESRPTASKPPALKNPPKFAP-LPENSVNFCFDSAFLTVRRVPAEVSNTHQNS 209
           +       E  PT +K PA   P + AP  P+            T  + PA  +      
Sbjct: 409 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT----- 463

Query: 210 YQPGRKHGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGTF 269
                K     + K P       ++       T T  E   P+   KP    P     T 
Sbjct: 464 -----KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT- 517

Query: 270 LHSENSAFESWNAHQPKLLERKDTAGTVPESKAPKHYGD--TTLLREPCP-PERTVSPCQ 326
                         +P     ++ A T P++ AP    +   T  +EP P   +  +P  
Sbjct: 518 -----------TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 566

Query: 327 VQASCSQEENRLAAGALSTSIPWGCRDPGAQVFA-VEGKAPSSQPDSQEKPAQPPWRKPK 385
            + +        A   L    P   + P  +  A    K P+S    +  P  P    P 
Sbjct: 567 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT 626

Query: 386 TGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISK 445
           T    KE    T +E   T  +G    T   P     +  A    + P     P    S 
Sbjct: 627 T---PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSD 682

Query: 446 LLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLKD 505
              P  P K    +   +PA  TP  P      +   P+  +      +K P+ +     
Sbjct: 683 KPAPTTP-KETAPTTPKEPAPTTPKKPAPTTP-ETPPPTTSEVSTPTTTKEPTTIH---- 736

Query: 506 VRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESP--PNELSKERPAD 563
                KS   S+P L               EP       P  LE SP  P   + + PA 
Sbjct: 737 -----KSPDESTPELSA-------------EPT------PKALENSPKEPGVPTTKTPAA 772

Query: 564 -----DPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAK 599
                  TA     ++D    P   +A   +T  TA T  K
Sbjct: 773 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK 813



 Score = 38.1 bits (87), Expect = 0.061
 Identities = 87/425 (20%), Positives = 134/425 (31%), Gaps = 53/425 (12%)

Query: 895  PRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAP 954
            P P   ++P    P+      T +   T               P + S     E +   P
Sbjct: 372  PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 431

Query: 955  KGNFPSMPLVGEGDRVKAPPDAAPGLVA-SNCKSGSADSGKLAAPWH----IPTI----- 1004
            K   P+ P        K P    P   A +  K  +  + K  AP       PT      
Sbjct: 432  KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 491

Query: 1005 -ALPEG---DIEDQPPPWQPENCW----EEQTPGFKSHFL-STPRAGPPGRRLVPSERA- 1054
               PE       ++P P  PE       EE TP        +TP+A  P     P+    
Sbjct: 492  PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 551

Query: 1055 --------NSPNPGSPGESSACSP---AASNIWEESSQAPGGP---ELLPEEPNQASPWA 1100
                      P P +P E++  +P   A + + E +   P  P   EL P    + +   
Sbjct: 552  KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 611

Query: 1101 SSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELP 1160
               PA  T +             +P      E   T +P+G+       PA T+ +   P
Sbjct: 612  CDKPAPTTPKGTAPTT-----PKEPAPTTPKEPAPT-TPKGTAPTTLKEPAPTTPKKPAP 665

Query: 1161 AQLERTASKPPAVPPKTEKALRRAKKLA--SKRRKTDQAQEKHGESQEGKPCPEDLE--- 1215
             +L  T +K P      + A    K+ A  + +       +K   +    P P   E   
Sbjct: 666  KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 725

Query: 1216 -QTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPAYPATQ 1274
              T + P    + P  + P + + P P          E   + PG P + TP    P   
Sbjct: 726  PTTTKEPTTIHKSPDESTPELSAEPTP-------KALENSPKEPGVPTTKTPAATKPEMT 778

Query: 1275 KVLQD 1279
               +D
Sbjct: 779  TTAKD 783



 Score = 35.0 bits (79), Expect = 0.52
 Identities = 64/281 (22%), Positives = 86/281 (30%), Gaps = 36/281 (12%)

Query: 1151 AGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQE-KHGESQEGKP 1209
            A TS  L  P     T +K PA+    E      K+ AS   K       K   +   +P
Sbjct: 188  APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 247

Query: 1210 CPEDLEQTQQRPLCPRE------------RPRHNFPVVRSLPPPVHRHSVSGF-SEPVGR 1256
             P     T+  P  P+E             P+   P     P P    S      EP   
Sbjct: 248  APTT---TKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 304

Query: 1257 RPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPSSE 1316
             P  P   TP    P T K   +P          P   K      P T +    +     
Sbjct: 305  TPKKPAPTTPKEPAPTTPK---EPT---------PTTPKEPA---PTTKEPAPTTPKEPA 349

Query: 1317 GASPEPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASAARARTQS 1376
              +P+ P P     P    P  +P P T   P   + +  APT  +  P  +   A T +
Sbjct: 350  PTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 408

Query: 1377 VHESGLQLDPGPHGDCTPHSAGQRPHGP-PQSPGEEGVEAP 1416
                    +P P    T   A   P  P P +P +     P
Sbjct: 409  KSAPTTPKEPSP--TTTKEPAPTTPKEPAPTTPKKPAPTTP 447


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 43.1 bits (100), Expect = 0.002
 Identities = 72/323 (22%), Positives = 113/323 (34%), Gaps = 41/323 (12%)

Query: 893  ELPRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQP 952
            E P P   E+P   AP        +TP     T  K  A    ++P   +     E +  
Sbjct: 561  EEPTPTTPEEP---APTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK---ETAPT 614

Query: 953  APKGNFPSMPLVGEGDRVK--APPDAAPGLV----ASNCKSGSADSGKLAAPWHIPTIAL 1006
             PKG  P+          K  AP + AP       ++ C   +  + K  AP    T   
Sbjct: 615  TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP---TTPKE 671

Query: 1007 PEGDIEDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVP-------SERANSPNP 1059
            P      +P P  P+          K    +TP+   P + L P       S  ++ P P
Sbjct: 672  PAPTTPKEPAPTTPKGT---APTTLKEPAPTTPKKPAP-KELAPTTTKGPTSTTSDKPAP 727

Query: 1060 GSPGESSACSPAASNIWEESSQAPGGPELLPEEPNQAS-PWASSSPARVTRREDLTHALV 1118
             +P E++  +P           AP  PE  P   ++ S P  +  P  + +  D      
Sbjct: 728  TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPD------ 781

Query: 1119 WEGGSDPLLELSAEDLRTL---SPRGSLLDVATSPAGTSGRLELPAQLERTASKPPAVPP 1175
                 +   ELSAE        SP+   +    +PA T   +   A+ + T       P 
Sbjct: 782  -----ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE 836

Query: 1176 KTEKALRRAKKLASKRRKTDQAQ 1198
             T  A +  K+ A+   KT +++
Sbjct: 837  TTTAAPKMTKETATTTEKTTESK 859



 Score = 40.8 bits (94), Expect = 0.009
 Identities = 83/407 (20%), Positives = 128/407 (31%), Gaps = 53/407 (13%)

Query: 209 SYQPGRKHGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGT 268
           S++ GR+       K  +  C    SF     D       K P+P   PV  E G G   
Sbjct: 77  SFERGRECDCDAQCKKYDKCCPDYESFCAEVKDNKKNRTKKKPTPK-PPVVDEAGSG--- 132

Query: 269 FLHSENSAFESWNAHQPKLLERKDTAGTVPESKAPKHYGDTTLLREPCPPERTVSPCQVQ 328
                              L+  D   T P++   +H   +T      P   T  P   +
Sbjct: 133 -------------------LDNGDFKVTTPDTSTTQHNKVST-----SPKITTAKPINPR 168

Query: 329 ASCSQEENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPSSQPDSQEKP--AQPPWRKPKT 386
            S     +     +L+ +     ++   +          +  D +EK   A+      KT
Sbjct: 169 PSLPPNSDTSKETSLTVN-----KETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 223

Query: 387 GKKGKESLQDTLEE---KTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNI 443
             K        L +   K +T  +GP L T   P     +  A   P EP     P    
Sbjct: 224 SAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT----PTTIK 279

Query: 444 SKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNL 503
           S   TP  P+     SA + P E  P+   +      KEP+   +++   +   S     
Sbjct: 280 SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 339

Query: 504 KD----VRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESPPNELSKE 559
           K+      K+   T    P      E T      K+   +     P   +E  P    K 
Sbjct: 340 KEPAPTTPKKPAPTTPKEPAPTTPKEPT--PTTPKEPAPTTKEPAPTTPKEPAPTAPKKP 397

Query: 560 RPADDPTASHINPQKD-PTA----DPSEPSADSYLTLSTAPTIAKAP 601
            P      +   P++  PT      P+ P   +  T  +APT  K P
Sbjct: 398 APTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 444



 Score = 38.5 bits (88), Expect = 0.047
 Identities = 69/347 (19%), Positives = 111/347 (31%), Gaps = 23/347 (6%)

Query: 1025 EEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPG 1084
            +E TP       +TP+   P            P P +  E +  +P           AP 
Sbjct: 271  KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 330

Query: 1085 GPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLEL-SAEDLRTLSPRGSL 1143
              +  P  P + +P     PA  T +E           + P     + ++    +P+   
Sbjct: 331  TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 390

Query: 1144 LDVATSPAGTSGRLELPAQLER---TASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEK 1200
                  PA T+ +   P   +    T +K P+     E A    K   +  ++      K
Sbjct: 391  PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 450

Query: 1201 HGESQEGKPCPEDLEQTQQRPLCPRE----RPRHNFPVVRSLPPPV--HRHSVSGFSEPV 1254
               +   +P P   +  +  P  P+E     P+   P     P P      + +   +P 
Sbjct: 451  SAPTTPKEPSPTTTK--EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 508

Query: 1255 GRRPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPS 1314
               P  P   TP    P T K L  P + E      P +        P T + +  + P 
Sbjct: 509  PTTPKEPAPTTPKETAPTTPKKL-TPTTPEKLAPTTPEKPA------PTTPEELAPTTP- 560

Query: 1315 SEGASPEPPPPDALAAPYVLYPGF--QPVPVTALMPLRCSSQLSAPT 1359
             E  +P  P   A   P    P    +P P T   P   + +  APT
Sbjct: 561  -EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 606



 Score = 38.1 bits (87), Expect = 0.061
 Identities = 106/545 (19%), Positives = 168/545 (30%), Gaps = 51/545 (9%)

Query: 96  AATFQQLPKYVQGEEKYPKTSPPPTPVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTES 155
           A T  + P     +E  P T   PTP   +   P +   +   P                
Sbjct: 343 APTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK--------------- 387

Query: 156 QRCESRPTASKPPALKNPPKFAPLPENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRK 215
              E  PTA K PA   P + AP          + A  T +    E S T      P   
Sbjct: 388 ---EPAPTAPKKPAPTTPKEPAPTTPK------EPAPTTTK----EPSPTTPKEPAPTTT 434

Query: 216 HGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENS 275
                ++K P      S+   P    + T  +   P+   +P    P +   T       
Sbjct: 435 KSAPTTTKEPAPTTTKSAPTTP-KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 493

Query: 276 AFESWNAHQPKLLERKDTAGTVPESKA---PKHYGDTTLLR-EPCPPERTVSPCQVQASC 331
                   +P     K  A T P+  A   PK    TT  +  P  PE+ ++P   +   
Sbjct: 494 T----TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK-LAPTTPEKPA 548

Query: 332 SQEENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPSSQPDSQEKPAQPPWRKPKTGKKGK 391
                 LA        P    +P            ++ P++ ++PA P   K       K
Sbjct: 549 PTTPEELAPTTPEEPTPTTPEEPAPTT------PKAAAPNTPKEPA-PTTPKEPAPTTPK 601

Query: 392 ESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISKLLTPII 451
           E    T +E   T  +G    T   P     +  A    + P    +P         P  
Sbjct: 602 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKEPTSTTCDKPAPTT 660

Query: 452 PSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLKDVRKRVK 511
           P K    +   +PA  TP  P      +   P+  +       K P+         K   
Sbjct: 661 P-KGTAPTTPKEPAPTTPKEPAPTTP-KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPT 718

Query: 512 STYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESPP--NELSKERPADDPTASH 569
           ST S  P      ++T      +  P +     P   E  PP  +E+S      +PT  H
Sbjct: 719 STTSDKP-APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 777

Query: 570 INPQKDPTADPSEPSADSYLTLSTAPTIAKAPFYVNGEAAERSSYENKEVEGELEMGPAG 629
            +P +      +EP+  +       P +         +    ++ ++K  E +L   P  
Sbjct: 778 KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPET 837

Query: 630 SSWCP 634
           ++  P
Sbjct: 838 TTAAP 842



 Score = 38.1 bits (87), Expect = 0.061
 Identities = 107/521 (20%), Positives = 157/521 (30%), Gaps = 73/521 (14%)

Query: 96  AATFQQLPKYVQGEEKYPKTSPPPTPVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTES 155
           A T  + P     +E  P T   P P   +   P +    +        T  K    T +
Sbjct: 390 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 449

Query: 156 QRC-----ESRPTASKPPALKNPPKFAP-LPENSVNFCFDSAFLTVRRVPAEVSNTHQNS 209
           +       E  PT +K PA   P + AP  P+            T  + PA  +      
Sbjct: 450 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT----- 504

Query: 210 YQPGRKHGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGTF 269
                K     + K P       ++       T T  E   P+   KP    P     T 
Sbjct: 505 -----KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT- 558

Query: 270 LHSENSAFESWNAHQPKLLERKDTAGTVPESKAPKHYGD--TTLLREPCP-PERTVSPCQ 326
                         +P     ++ A T P++ AP    +   T  +EP P   +  +P  
Sbjct: 559 -----------TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 607

Query: 327 VQASCSQEENRLAAGALSTSIPWGCRDPGAQVFA-VEGKAPSSQPDSQEKPAQPPWRKPK 385
            + +        A   L    P   + P  +  A    K P+S    +  P  P    P 
Sbjct: 608 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT 667

Query: 386 TGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISK 445
           T    KE    T +E   T  +G    T   P     +  A    + P     P    S 
Sbjct: 668 T---PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSD 723

Query: 446 LLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLKD 505
              P  P K    +   +PA  TP  P      +   P+  +      +K P+ +     
Sbjct: 724 KPAPTTP-KETAPTTPKEPAPTTPKKPAPTTP-ETPPPTTSEVSTPTTTKEPTTIH---- 777

Query: 506 VRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESP--PNELSKERPAD 563
                KS   S+P L               EP       P  LE SP  P   + + PA 
Sbjct: 778 -----KSPDESTPELSA-------------EPT------PKALENSPKEPGVPTTKTPAA 813

Query: 564 -----DPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAK 599
                  TA     ++D    P   +A   +T  TA T  K
Sbjct: 814 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK 854



 Score = 38.1 bits (87), Expect = 0.061
 Identities = 87/425 (20%), Positives = 134/425 (31%), Gaps = 53/425 (12%)

Query: 895  PRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAP 954
            P P   ++P    P+      T +   T               P + S     E +   P
Sbjct: 413  PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 472

Query: 955  KGNFPSMPLVGEGDRVKAPPDAAPGLVA-SNCKSGSADSGKLAAPWH----IPTI----- 1004
            K   P+ P        K P    P   A +  K  +  + K  AP       PT      
Sbjct: 473  KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 532

Query: 1005 -ALPEG---DIEDQPPPWQPENCW----EEQTPGFKSHFL-STPRAGPPGRRLVPSERA- 1054
               PE       ++P P  PE       EE TP        +TP+A  P     P+    
Sbjct: 533  PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 592

Query: 1055 --------NSPNPGSPGESSACSP---AASNIWEESSQAPGGP---ELLPEEPNQASPWA 1100
                      P P +P E++  +P   A + + E +   P  P   EL P    + +   
Sbjct: 593  KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 652

Query: 1101 SSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELP 1160
               PA  T +             +P      E   T +P+G+       PA T+ +   P
Sbjct: 653  CDKPAPTTPKGTAPTT-----PKEPAPTTPKEPAPT-TPKGTAPTTLKEPAPTTPKKPAP 706

Query: 1161 AQLERTASKPPAVPPKTEKALRRAKKLA--SKRRKTDQAQEKHGESQEGKPCPEDLE--- 1215
             +L  T +K P      + A    K+ A  + +       +K   +    P P   E   
Sbjct: 707  KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 766

Query: 1216 -QTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPAYPATQ 1274
              T + P    + P  + P + + P P          E   + PG P + TP    P   
Sbjct: 767  PTTTKEPTTIHKSPDESTPELSAEPTP-------KALENSPKEPGVPTTKTPAATKPEMT 819

Query: 1275 KVLQD 1279
               +D
Sbjct: 820  TTAKD 824



 Score = 35.0 bits (79), Expect = 0.52
 Identities = 64/281 (22%), Positives = 86/281 (30%), Gaps = 36/281 (12%)

Query: 1151 AGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQE-KHGESQEGKP 1209
            A TS  L  P     T +K PA+    E      K+ AS   K       K   +   +P
Sbjct: 229  APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 288

Query: 1210 CPEDLEQTQQRPLCPRE------------RPRHNFPVVRSLPPPVHRHSVSGF-SEPVGR 1256
             P     T+  P  P+E             P+   P     P P    S      EP   
Sbjct: 289  APTT---TKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 345

Query: 1257 RPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPSSE 1316
             P  P   TP    P T K   +P          P   K      P T +    +     
Sbjct: 346  TPKKPAPTTPKEPAPTTPK---EPT---------PTTPKEPA---PTTKEPAPTTPKEPA 390

Query: 1317 GASPEPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASAARARTQS 1376
              +P+ P P     P    P  +P P T   P   + +  APT  +  P  +   A T +
Sbjct: 391  PTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 449

Query: 1377 VHESGLQLDPGPHGDCTPHSAGQRPHGP-PQSPGEEGVEAP 1416
                    +P P    T   A   P  P P +P +     P
Sbjct: 450  KSAPTTPKEPSP--TTTKEPAPTTPKEPAPTTPKKPAPTTP 488


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 43.1 bits (100), Expect = 0.002
 Identities = 72/323 (22%), Positives = 113/323 (34%), Gaps = 41/323 (12%)

Query: 893  ELPRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQP 952
            E P P   E+P   AP        +TP     T  K  A    ++P   +     E +  
Sbjct: 613  EEPTPTTPEEP---APTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK---ETAPT 666

Query: 953  APKGNFPSMPLVGEGDRVK--APPDAAPGLV----ASNCKSGSADSGKLAAPWHIPTIAL 1006
             PKG  P+          K  AP + AP       ++ C   +  + K  AP    T   
Sbjct: 667  TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP---TTPKE 723

Query: 1007 PEGDIEDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVP-------SERANSPNP 1059
            P      +P P  P+          K    +TP+   P + L P       S  ++ P P
Sbjct: 724  PAPTTPKEPAPTTPKGT---APTTLKEPAPTTPKKPAP-KELAPTTTKGPTSTTSDKPAP 779

Query: 1060 GSPGESSACSPAASNIWEESSQAPGGPELLPEEPNQAS-PWASSSPARVTRREDLTHALV 1118
             +P E++  +P           AP  PE  P   ++ S P  +  P  + +  D      
Sbjct: 780  TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPD------ 833

Query: 1119 WEGGSDPLLELSAEDLRTL---SPRGSLLDVATSPAGTSGRLELPAQLERTASKPPAVPP 1175
                 +   ELSAE        SP+   +    +PA T   +   A+ + T       P 
Sbjct: 834  -----ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE 888

Query: 1176 KTEKALRRAKKLASKRRKTDQAQ 1198
             T  A +  K+ A+   KT +++
Sbjct: 889  TTTAAPKMTKETATTTEKTTESK 911



 Score = 38.5 bits (88), Expect = 0.047
 Identities = 69/347 (19%), Positives = 111/347 (31%), Gaps = 23/347 (6%)

Query: 1025 EEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPG 1084
            +E TP       +TP+   P            P P +  E +  +P           AP 
Sbjct: 323  KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 382

Query: 1085 GPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLEL-SAEDLRTLSPRGSL 1143
              +  P  P + +P     PA  T +E           + P     + ++    +P+   
Sbjct: 383  TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 442

Query: 1144 LDVATSPAGTSGRLELPAQLER---TASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEK 1200
                  PA T+ +   P   +    T +K P+     E A    K   +  ++      K
Sbjct: 443  PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 502

Query: 1201 HGESQEGKPCPEDLEQTQQRPLCPRE----RPRHNFPVVRSLPPPV--HRHSVSGFSEPV 1254
               +   +P P   +  +  P  P+E     P+   P     P P      + +   +P 
Sbjct: 503  SAPTTPKEPSPTTTK--EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 560

Query: 1255 GRRPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPS 1314
               P  P   TP    P T K L  P + E      P +        P T + +  + P 
Sbjct: 561  PTTPKEPAPTTPKETAPTTPKKL-TPTTPEKLAPTTPEKPA------PTTPEELAPTTP- 612

Query: 1315 SEGASPEPPPPDALAAPYVLYPGF--QPVPVTALMPLRCSSQLSAPT 1359
             E  +P  P   A   P    P    +P P T   P   + +  APT
Sbjct: 613  -EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 658



 Score = 38.1 bits (87), Expect = 0.061
 Identities = 106/545 (19%), Positives = 168/545 (30%), Gaps = 51/545 (9%)

Query: 96  AATFQQLPKYVQGEEKYPKTSPPPTPVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTES 155
           A T  + P     +E  P T   PTP   +   P +   +   P                
Sbjct: 395 APTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK--------------- 439

Query: 156 QRCESRPTASKPPALKNPPKFAPLPENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRK 215
              E  PTA K PA   P + AP          + A  T +    E S T      P   
Sbjct: 440 ---EPAPTAPKKPAPTTPKEPAPTTPK------EPAPTTTK----EPSPTTPKEPAPTTT 486

Query: 216 HGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENS 275
                ++K P      S+   P    + T  +   P+   +P    P +   T       
Sbjct: 487 KSAPTTTKEPAPTTTKSAPTTP-KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 545

Query: 276 AFESWNAHQPKLLERKDTAGTVPESKA---PKHYGDTTLLR-EPCPPERTVSPCQVQASC 331
                   +P     K  A T P+  A   PK    TT  +  P  PE+ ++P   +   
Sbjct: 546 T----TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK-LAPTTPEKPA 600

Query: 332 SQEENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPSSQPDSQEKPAQPPWRKPKTGKKGK 391
                 LA        P    +P            ++ P++ ++PA P   K       K
Sbjct: 601 PTTPEELAPTTPEEPTPTTPEEPAPTT------PKAAAPNTPKEPA-PTTPKEPAPTTPK 653

Query: 392 ESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISKLLTPII 451
           E    T +E   T  +G    T   P     +  A    + P    +P         P  
Sbjct: 654 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKEPTSTTCDKPAPTT 712

Query: 452 PSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLKDVRKRVK 511
           P K    +   +PA  TP  P      +   P+  +       K P+         K   
Sbjct: 713 P-KGTAPTTPKEPAPTTPKEPAPTTP-KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPT 770

Query: 512 STYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESPP--NELSKERPADDPTASH 569
           ST S  P      ++T      +  P +     P   E  PP  +E+S      +PT  H
Sbjct: 771 STTSDKP-APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 829

Query: 570 INPQKDPTADPSEPSADSYLTLSTAPTIAKAPFYVNGEAAERSSYENKEVEGELEMGPAG 629
            +P +      +EP+  +       P +         +    ++ ++K  E +L   P  
Sbjct: 830 KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPET 889

Query: 630 SSWCP 634
           ++  P
Sbjct: 890 TTAAP 894



 Score = 38.1 bits (87), Expect = 0.061
 Identities = 107/521 (20%), Positives = 157/521 (30%), Gaps = 73/521 (14%)

Query: 96  AATFQQLPKYVQGEEKYPKTSPPPTPVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTES 155
           A T  + P     +E  P T   P P   +   P +    +        T  K    T +
Sbjct: 442 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 501

Query: 156 QRC-----ESRPTASKPPALKNPPKFAP-LPENSVNFCFDSAFLTVRRVPAEVSNTHQNS 209
           +       E  PT +K PA   P + AP  P+            T  + PA  +      
Sbjct: 502 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT----- 556

Query: 210 YQPGRKHGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGTF 269
                K     + K P       ++       T T  E   P+   KP    P     T 
Sbjct: 557 -----KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT- 610

Query: 270 LHSENSAFESWNAHQPKLLERKDTAGTVPESKAPKHYGD--TTLLREPCP-PERTVSPCQ 326
                         +P     ++ A T P++ AP    +   T  +EP P   +  +P  
Sbjct: 611 -----------TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 659

Query: 327 VQASCSQEENRLAAGALSTSIPWGCRDPGAQVFA-VEGKAPSSQPDSQEKPAQPPWRKPK 385
            + +        A   L    P   + P  +  A    K P+S    +  P  P    P 
Sbjct: 660 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT 719

Query: 386 TGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISK 445
           T    KE    T +E   T  +G    T   P     +  A    + P     P    S 
Sbjct: 720 T---PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSD 775

Query: 446 LLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLKD 505
              P  P K    +   +PA  TP  P      +   P+  +      +K P+ +     
Sbjct: 776 KPAPTTP-KETAPTTPKEPAPTTPKKPAPTTP-ETPPPTTSEVSTPTTTKEPTTIH---- 829

Query: 506 VRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESP--PNELSKERPAD 563
                KS   S+P L               EP       P  LE SP  P   + + PA 
Sbjct: 830 -----KSPDESTPELSA-------------EPT------PKALENSPKEPGVPTTKTPAA 865

Query: 564 -----DPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAK 599
                  TA     ++D    P   +A   +T  TA T  K
Sbjct: 866 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK 906



 Score = 38.1 bits (87), Expect = 0.061
 Identities = 87/425 (20%), Positives = 134/425 (31%), Gaps = 53/425 (12%)

Query: 895  PRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAP 954
            P P   ++P    P+      T +   T               P + S     E +   P
Sbjct: 465  PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 524

Query: 955  KGNFPSMPLVGEGDRVKAPPDAAPGLVA-SNCKSGSADSGKLAAPWH----IPTI----- 1004
            K   P+ P        K P    P   A +  K  +  + K  AP       PT      
Sbjct: 525  KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 584

Query: 1005 -ALPEG---DIEDQPPPWQPENCW----EEQTPGFKSHFL-STPRAGPPGRRLVPSERA- 1054
               PE       ++P P  PE       EE TP        +TP+A  P     P+    
Sbjct: 585  PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 644

Query: 1055 --------NSPNPGSPGESSACSP---AASNIWEESSQAPGGP---ELLPEEPNQASPWA 1100
                      P P +P E++  +P   A + + E +   P  P   EL P    + +   
Sbjct: 645  KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 704

Query: 1101 SSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELP 1160
               PA  T +             +P      E   T +P+G+       PA T+ +   P
Sbjct: 705  CDKPAPTTPKGTAPTT-----PKEPAPTTPKEPAPT-TPKGTAPTTLKEPAPTTPKKPAP 758

Query: 1161 AQLERTASKPPAVPPKTEKALRRAKKLA--SKRRKTDQAQEKHGESQEGKPCPEDLE--- 1215
             +L  T +K P      + A    K+ A  + +       +K   +    P P   E   
Sbjct: 759  KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 818

Query: 1216 -QTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPAYPATQ 1274
              T + P    + P  + P + + P P          E   + PG P + TP    P   
Sbjct: 819  PTTTKEPTTIHKSPDESTPELSAEPTP-------KALENSPKEPGVPTTKTPAATKPEMT 871

Query: 1275 KVLQD 1279
               +D
Sbjct: 872  TTAKD 876



 Score = 37.4 bits (85), Expect = 0.10
 Identities = 48/210 (22%), Positives = 71/210 (33%), Gaps = 15/210 (7%)

Query: 401 KTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHALDSA 460
           K +T  +GP L T   P     +  A   P EP     P    S   TP  P+     SA
Sbjct: 293 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT----PTTIKSAPTTPKEPAPTTTKSA 348

Query: 461 DSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLKD----VRKRVKSTYSS 516
            + P E  P+   +      KEP+   +++   +   S     K+      K+   T   
Sbjct: 349 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 408

Query: 517 SPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESPPNELSKERPADDPTASHINPQKD- 575
            P      E T      K+   +     P   +E  P    K  P      +   P++  
Sbjct: 409 EPAPTTPKEPT--PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 466

Query: 576 PTA----DPSEPSADSYLTLSTAPTIAKAP 601
           PT      P+ P   +  T  +APT  K P
Sbjct: 467 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 496



 Score = 35.0 bits (79), Expect = 0.52
 Identities = 64/281 (22%), Positives = 86/281 (30%), Gaps = 36/281 (12%)

Query: 1151 AGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQE-KHGESQEGKP 1209
            A TS  L  P     T +K PA+    E      K+ AS   K       K   +   +P
Sbjct: 281  APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 340

Query: 1210 CPEDLEQTQQRPLCPRE------------RPRHNFPVVRSLPPPVHRHSVSGF-SEPVGR 1256
             P     T+  P  P+E             P+   P     P P    S      EP   
Sbjct: 341  APTT---TKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 397

Query: 1257 RPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPSSE 1316
             P  P   TP    P T K   +P          P   K      P T +    +     
Sbjct: 398  TPKKPAPTTPKEPAPTTPK---EPT---------PTTPKEPA---PTTKEPAPTTPKEPA 442

Query: 1317 GASPEPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASAARARTQS 1376
              +P+ P P     P    P  +P P T   P   + +  APT  +  P  +   A T +
Sbjct: 443  PTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 501

Query: 1377 VHESGLQLDPGPHGDCTPHSAGQRPHGP-PQSPGEEGVEAP 1416
                    +P P    T   A   P  P P +P +     P
Sbjct: 502  KSAPTTPKEPSP--TTTKEPAPTTPKEPAPTTPKKPAPTTP 540


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 43.1 bits (100), Expect = 0.002
 Identities = 72/323 (22%), Positives = 113/323 (34%), Gaps = 41/323 (12%)

Query: 893  ELPRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQP 952
            E P P   E+P   AP        +TP     T  K  A    ++P   +     E +  
Sbjct: 654  EEPTPTTPEEP---APTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK---ETAPT 707

Query: 953  APKGNFPSMPLVGEGDRVK--APPDAAPGLV----ASNCKSGSADSGKLAAPWHIPTIAL 1006
             PKG  P+          K  AP + AP       ++ C   +  + K  AP    T   
Sbjct: 708  TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP---TTPKE 764

Query: 1007 PEGDIEDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVP-------SERANSPNP 1059
            P      +P P  P+          K    +TP+   P + L P       S  ++ P P
Sbjct: 765  PAPTTPKEPAPTTPKGT---APTTLKEPAPTTPKKPAP-KELAPTTTKGPTSTTSDKPAP 820

Query: 1060 GSPGESSACSPAASNIWEESSQAPGGPELLPEEPNQAS-PWASSSPARVTRREDLTHALV 1118
             +P E++  +P           AP  PE  P   ++ S P  +  P  + +  D      
Sbjct: 821  TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPD------ 874

Query: 1119 WEGGSDPLLELSAEDLRTL---SPRGSLLDVATSPAGTSGRLELPAQLERTASKPPAVPP 1175
                 +   ELSAE        SP+   +    +PA T   +   A+ + T       P 
Sbjct: 875  -----ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE 929

Query: 1176 KTEKALRRAKKLASKRRKTDQAQ 1198
             T  A +  K+ A+   KT +++
Sbjct: 930  TTTAAPKMTKETATTTEKTTESK 952



 Score = 38.5 bits (88), Expect = 0.047
 Identities = 69/347 (19%), Positives = 111/347 (31%), Gaps = 23/347 (6%)

Query: 1025 EEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPG 1084
            +E TP       +TP+   P            P P +  E +  +P           AP 
Sbjct: 364  KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 423

Query: 1085 GPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLEL-SAEDLRTLSPRGSL 1143
              +  P  P + +P     PA  T +E           + P     + ++    +P+   
Sbjct: 424  TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 483

Query: 1144 LDVATSPAGTSGRLELPAQLER---TASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEK 1200
                  PA T+ +   P   +    T +K P+     E A    K   +  ++      K
Sbjct: 484  PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 543

Query: 1201 HGESQEGKPCPEDLEQTQQRPLCPRE----RPRHNFPVVRSLPPPV--HRHSVSGFSEPV 1254
               +   +P P   +  +  P  P+E     P+   P     P P      + +   +P 
Sbjct: 544  SAPTTPKEPSPTTTK--EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 601

Query: 1255 GRRPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPS 1314
               P  P   TP    P T K L  P + E      P +        P T + +  + P 
Sbjct: 602  PTTPKEPAPTTPKETAPTTPKKL-TPTTPEKLAPTTPEKPA------PTTPEELAPTTP- 653

Query: 1315 SEGASPEPPPPDALAAPYVLYPGF--QPVPVTALMPLRCSSQLSAPT 1359
             E  +P  P   A   P    P    +P P T   P   + +  APT
Sbjct: 654  -EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 699



 Score = 38.1 bits (87), Expect = 0.061
 Identities = 106/545 (19%), Positives = 168/545 (30%), Gaps = 51/545 (9%)

Query: 96  AATFQQLPKYVQGEEKYPKTSPPPTPVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTES 155
           A T  + P     +E  P T   PTP   +   P +   +   P                
Sbjct: 436 APTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK--------------- 480

Query: 156 QRCESRPTASKPPALKNPPKFAPLPENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRK 215
              E  PTA K PA   P + AP          + A  T +    E S T      P   
Sbjct: 481 ---EPAPTAPKKPAPTTPKEPAPTTPK------EPAPTTTK----EPSPTTPKEPAPTTT 527

Query: 216 HGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENS 275
                ++K P      S+   P    + T  +   P+   +P    P +   T       
Sbjct: 528 KSAPTTTKEPAPTTTKSAPTTP-KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 586

Query: 276 AFESWNAHQPKLLERKDTAGTVPESKA---PKHYGDTTLLR-EPCPPERTVSPCQVQASC 331
                   +P     K  A T P+  A   PK    TT  +  P  PE+ ++P   +   
Sbjct: 587 T----TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK-LAPTTPEKPA 641

Query: 332 SQEENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPSSQPDSQEKPAQPPWRKPKTGKKGK 391
                 LA        P    +P            ++ P++ ++PA P   K       K
Sbjct: 642 PTTPEELAPTTPEEPTPTTPEEPAPTT------PKAAAPNTPKEPA-PTTPKEPAPTTPK 694

Query: 392 ESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISKLLTPII 451
           E    T +E   T  +G    T   P     +  A    + P    +P         P  
Sbjct: 695 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKEPTSTTCDKPAPTT 753

Query: 452 PSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLKDVRKRVK 511
           P K    +   +PA  TP  P      +   P+  +       K P+         K   
Sbjct: 754 P-KGTAPTTPKEPAPTTPKEPAPTTP-KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPT 811

Query: 512 STYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESPP--NELSKERPADDPTASH 569
           ST S  P      ++T      +  P +     P   E  PP  +E+S      +PT  H
Sbjct: 812 STTSDKP-APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 870

Query: 570 INPQKDPTADPSEPSADSYLTLSTAPTIAKAPFYVNGEAAERSSYENKEVEGELEMGPAG 629
            +P +      +EP+  +       P +         +    ++ ++K  E +L   P  
Sbjct: 871 KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPET 930

Query: 630 SSWCP 634
           ++  P
Sbjct: 931 TTAAP 935



 Score = 38.1 bits (87), Expect = 0.061
 Identities = 107/521 (20%), Positives = 157/521 (30%), Gaps = 73/521 (14%)

Query: 96  AATFQQLPKYVQGEEKYPKTSPPPTPVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTES 155
           A T  + P     +E  P T   P P   +   P +    +        T  K    T +
Sbjct: 483 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 542

Query: 156 QRC-----ESRPTASKPPALKNPPKFAP-LPENSVNFCFDSAFLTVRRVPAEVSNTHQNS 209
           +       E  PT +K PA   P + AP  P+            T  + PA  +      
Sbjct: 543 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT----- 597

Query: 210 YQPGRKHGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGTF 269
                K     + K P       ++       T T  E   P+   KP    P     T 
Sbjct: 598 -----KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT- 651

Query: 270 LHSENSAFESWNAHQPKLLERKDTAGTVPESKAPKHYGD--TTLLREPCP-PERTVSPCQ 326
                         +P     ++ A T P++ AP    +   T  +EP P   +  +P  
Sbjct: 652 -----------TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 700

Query: 327 VQASCSQEENRLAAGALSTSIPWGCRDPGAQVFA-VEGKAPSSQPDSQEKPAQPPWRKPK 385
            + +        A   L    P   + P  +  A    K P+S    +  P  P    P 
Sbjct: 701 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT 760

Query: 386 TGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISK 445
           T    KE    T +E   T  +G    T   P     +  A    + P     P    S 
Sbjct: 761 T---PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSD 816

Query: 446 LLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLKD 505
              P  P K    +   +PA  TP  P      +   P+  +      +K P+ +     
Sbjct: 817 KPAPTTP-KETAPTTPKEPAPTTPKKPAPTTP-ETPPPTTSEVSTPTTTKEPTTIH---- 870

Query: 506 VRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESP--PNELSKERPAD 563
                KS   S+P L               EP       P  LE SP  P   + + PA 
Sbjct: 871 -----KSPDESTPELSA-------------EPT------PKALENSPKEPGVPTTKTPAA 906

Query: 564 -----DPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAK 599
                  TA     ++D    P   +A   +T  TA T  K
Sbjct: 907 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK 947



 Score = 38.1 bits (87), Expect = 0.061
 Identities = 87/425 (20%), Positives = 134/425 (31%), Gaps = 53/425 (12%)

Query: 895  PRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAP 954
            P P   ++P    P+      T +   T               P + S     E +   P
Sbjct: 506  PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 565

Query: 955  KGNFPSMPLVGEGDRVKAPPDAAPGLVA-SNCKSGSADSGKLAAPWH----IPTI----- 1004
            K   P+ P        K P    P   A +  K  +  + K  AP       PT      
Sbjct: 566  KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 625

Query: 1005 -ALPEG---DIEDQPPPWQPENCW----EEQTPGFKSHFL-STPRAGPPGRRLVPSERA- 1054
               PE       ++P P  PE       EE TP        +TP+A  P     P+    
Sbjct: 626  PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 685

Query: 1055 --------NSPNPGSPGESSACSP---AASNIWEESSQAPGGP---ELLPEEPNQASPWA 1100
                      P P +P E++  +P   A + + E +   P  P   EL P    + +   
Sbjct: 686  KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 745

Query: 1101 SSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELP 1160
               PA  T +             +P      E   T +P+G+       PA T+ +   P
Sbjct: 746  CDKPAPTTPKGTAPTT-----PKEPAPTTPKEPAPT-TPKGTAPTTLKEPAPTTPKKPAP 799

Query: 1161 AQLERTASKPPAVPPKTEKALRRAKKLA--SKRRKTDQAQEKHGESQEGKPCPEDLE--- 1215
             +L  T +K P      + A    K+ A  + +       +K   +    P P   E   
Sbjct: 800  KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 859

Query: 1216 -QTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPAYPATQ 1274
              T + P    + P  + P + + P P          E   + PG P + TP    P   
Sbjct: 860  PTTTKEPTTIHKSPDESTPELSAEPTP-------KALENSPKEPGVPTTKTPAATKPEMT 912

Query: 1275 KVLQD 1279
               +D
Sbjct: 913  TTAKD 917



 Score = 37.4 bits (85), Expect = 0.10
 Identities = 48/210 (22%), Positives = 71/210 (33%), Gaps = 15/210 (7%)

Query: 401 KTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHALDSA 460
           K +T  +GP L T   P     +  A   P EP     P    S   TP  P+     SA
Sbjct: 334 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT----PTTIKSAPTTPKEPAPTTTKSA 389

Query: 461 DSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLKD----VRKRVKSTYSS 516
            + P E  P+   +      KEP+   +++   +   S     K+      K+   T   
Sbjct: 390 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 449

Query: 517 SPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESPPNELSKERPADDPTASHINPQKD- 575
            P      E T      K+   +     P   +E  P    K  P      +   P++  
Sbjct: 450 EPAPTTPKEPT--PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 507

Query: 576 PTA----DPSEPSADSYLTLSTAPTIAKAP 601
           PT      P+ P   +  T  +APT  K P
Sbjct: 508 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 537



 Score = 35.0 bits (79), Expect = 0.52
 Identities = 64/281 (22%), Positives = 86/281 (30%), Gaps = 36/281 (12%)

Query: 1151 AGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQE-KHGESQEGKP 1209
            A TS  L  P     T +K PA+    E      K+ AS   K       K   +   +P
Sbjct: 322  APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 381

Query: 1210 CPEDLEQTQQRPLCPRE------------RPRHNFPVVRSLPPPVHRHSVSGF-SEPVGR 1256
             P     T+  P  P+E             P+   P     P P    S      EP   
Sbjct: 382  APTT---TKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 438

Query: 1257 RPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPSSE 1316
             P  P   TP    P T K   +P          P   K      P T +    +     
Sbjct: 439  TPKKPAPTTPKEPAPTTPK---EPT---------PTTPKEPA---PTTKEPAPTTPKEPA 483

Query: 1317 GASPEPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASAARARTQS 1376
              +P+ P P     P    P  +P P T   P   + +  APT  +  P  +   A T +
Sbjct: 484  PTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 542

Query: 1377 VHESGLQLDPGPHGDCTPHSAGQRPHGP-PQSPGEEGVEAP 1416
                    +P P    T   A   P  P P +P +     P
Sbjct: 543  KSAPTTPKEPSP--TTTKEPAPTTPKEPAPTTPKKPAPTTP 581


>gi|148806908 fibronectin type III domain containing 1 [Homo sapiens]
          Length = 1894

 Score = 43.1 bits (100), Expect = 0.002
 Identities = 66/277 (23%), Positives = 96/277 (34%), Gaps = 32/277 (11%)

Query: 1146 VATSPAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQ 1205
            V  SP G + + +L   L+         P K +   ++A++L    + T+   E+   S+
Sbjct: 493  VPASPQGRNAK-DLLLDLKNKILANGGAPRKPQLRAKKAEEL--DLQSTEITGEEELGSR 549

Query: 1206 EGKPCPEDLEQTQQRPLCPRERPRHNF-----PVVRSLPPPVHRHS---VSGFSEPVGRR 1257
            E  P      Q Q+R L P  R  H+        VR+  P + R       GFS     R
Sbjct: 550  EDSPMSPSDTQDQKRTLRPPSRHGHSVVAPGRTAVRARMPALPRREGVDKPGFSLATQPR 609

Query: 1258 PGGPQSLTPLPAYPA-TQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSI-PSS 1315
            PG P S +  PA+ A TQ     P         LP  +      D +  +    S+ P  
Sbjct: 610  PGAPPSASASPAHHASTQGTSHRP--------SLPASLNDNDLVDSDEDERAVGSLHPKG 661

Query: 1316 EGASPEP-------PPPDALAAPYVLYPGFQPVPVTALMP----LRCSSQLSAPTFLRQG 1364
              A P P        P   L     ++PG +P       P        S  SAP      
Sbjct: 662  AFAQPRPALSPSRQSPSSVLRDRSSVHPGAKPASPARRTPHSGAAEEDSSASAPPSRLSP 721

Query: 1365 PRASAARARTQSVHESGLQLDPGPHGDCTPHSAGQRP 1401
            P   ++R      H S      G  G+  P +    P
Sbjct: 722  PHGGSSRLLPTQPHLSSPLSKGGKDGEDAPATNSNAP 758



 Score = 31.2 bits (69), Expect = 7.5
 Identities = 78/399 (19%), Positives = 135/399 (33%), Gaps = 73/399 (18%)

Query: 888  GHKEEELPRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARM 947
            G +E+E P P            N  +  +S    +RG        ++   P +G+S+ R 
Sbjct: 877  GDEEDEKPLP--------ATVVNDHVPSSSRQPISRGWE------DLRRSPQRGASLHRK 922

Query: 948  E---------ASQPAPKGNFPSMPLVGE-------GDRVKAPPDAAPGLVASNCKSGSAD 991
            E          +   P+G + S+    +        D     P A PG    +       
Sbjct: 923  EPIPENPKSTGADTHPQGKYSSLASKAQDVQQSTDADTEGHSPKAQPGSTDRHASPARPP 982

Query: 992  SGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFKSHF---------LSTPRAG 1042
            + +      +P    P    + QPPP        +  PG +S           LS  +AG
Sbjct: 983  AARSQQHPSVPRRMTPGRAPQQQPPP---PVATSQHHPGPQSRDAGRSPSQPRLSLTQAG 1039

Query: 1043 PPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPGGPELLPEEPNQASPWASS 1102
             P     P+ +  S +   P  +S+     + +  +   A G  +   ++  +       
Sbjct: 1040 RPR----PTSQGRSHSSSDPYTASSRGMLPTALQNQDEDAQGSYD---DDSTEVEAQDVR 1092

Query: 1103 SPARVTRREDLTHALV-WEGGSDPLLELSAEDLRTLSPRGSLLDVA--TSPAGTSGRLEL 1159
            +PA   R ++   +L   +    P    +  D R  S RG     A  + P G   R  +
Sbjct: 1093 APAHAARAKEAAASLPKHQQVESPTGAGAGGDHR--SQRGHAASPARPSRPGGPQSRARV 1150

Query: 1160 PAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGES--------------- 1204
            P++     S+PP+  P + K+ +     A    + D    K G+                
Sbjct: 1151 PSRAAPGKSEPPSKRPLSSKSQQSVS--AEDDEEEDAGFFKGGKEDLLSSSVPKWPSSST 1208

Query: 1205 -QEGKPCPEDLEQTQQRP-LCPRERPRHNFPVVRSLPPP 1241
             + GK     L + ++ P +    R     PV R LPPP
Sbjct: 1209 PRGGKDADGSLAKEEREPAIALAPRGGSLAPVKRPLPPP 1247


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
            sapiens]
          Length = 2715

 Score = 43.1 bits (100), Expect = 0.002
 Identities = 90/436 (20%), Positives = 137/436 (31%), Gaps = 65/436 (14%)

Query: 1025 EEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPG 1084
            EE  P  +      P   PP     PS     P P +      C P    +      +P 
Sbjct: 388  EEMMPAAEKEEAKLPP--PPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPP 445

Query: 1085 GPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLL 1144
             P    E+     P   ++ +R   R  LT +           + +  +     P G+  
Sbjct: 446  PPPAQEEQEESPPPVVPATCSRKRGRPPLTPS-----------QRAEREAARAGPEGTSP 494

Query: 1145 DVATSPAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKK-----LASKRRKTDQAQE 1199
               T    T G  E            P V PK+   L+  ++     ++++  +  +   
Sbjct: 495  PTPTPSTATGGPPE----------DSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPR 544

Query: 1200 KHGESQEGKPCPEDLEQTQQRPL-----CPRE------RPRHNFPVVRSLPPPVHRHSVS 1248
            +  +    KP   ++    + P+      P+E       PR   P    +P P  R S+ 
Sbjct: 545  RFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSI- 603

Query: 1249 GFSEPVGRRPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGK-- 1306
               EP  R     + L P P  P        P          PL ++   F   E     
Sbjct: 604  -LREPTFRWTSLTRELPPPPPAPPPPPA-PSPPPAPATSSRRPLLLRAPQFTPSEAHLKI 661

Query: 1307 YVKVSIPSSEGA--SPEPPPPDALAAP------------YVLYPGFQPVPVTALMPLRCS 1352
            Y  V  P   GA  +PEP PP A  +P            ++  P F PV  T   P++  
Sbjct: 662  YESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTT---PVKAE 718

Query: 1353 SQLSAPTFLRQGPRASAARARTQSVHESGLQLDPGPHGDCTPHSAGQRPHGPPQSPGEEG 1412
                    L  GP+  A   +        LQ    P     P    Q P  P Q P  E 
Sbjct: 719  VSPHGAPALSNGPQTQAQLLQPL----QALQTQLLPQALPPPQPQLQPPPSPQQMPPLEK 774

Query: 1413 VEAPGLGIISTDDLED 1428
                G+G +    +E+
Sbjct: 775  ARIAGVGSLPLSGVEE 790



 Score = 32.7 bits (73), Expect = 2.6
 Identities = 38/162 (23%), Positives = 61/162 (37%), Gaps = 3/162 (1%)

Query: 1190 KRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSG 1249
            + +K ++ ++K GE +E +   E++    ++       P    P   S PPP+   S S 
Sbjct: 366  EEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLT-PPAPSPPPPLPPPSTSP 424

Query: 1250 FSEPVGRRPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVK 1309
               P+   P  P S  PLP+ P      +  +S    V     + + +    P      +
Sbjct: 425  -PPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAERE 483

Query: 1310 VSIPSSEGASPEPPPPD-ALAAPYVLYPGFQPVPVTALMPLR 1350
             +    EG SP  P P  A   P    P   P   T L  +R
Sbjct: 484  AARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIR 525


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.128    0.381 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 72,614,078
Number of Sequences: 37866
Number of extensions: 4372340
Number of successful extensions: 20307
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 670
Number of HSP's that attempted gapping in prelim test: 17111
Number of HSP's gapped (non-prelim): 3925
length of query: 1435
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1320
effective length of database: 13,892,928
effective search space: 18338664960
effective search space used: 18338664960
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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