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Search of human proteins with 206597543
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|206597543 hypothetical protein LOC118461 isoform 1 [Homo
sapiens]
(1435 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|206597543 hypothetical protein LOC118461 isoform 1 [Homo sapi... 2944 0.0
gi|49574498 hypothetical protein LOC118461 isoform 2 [Homo sapiens] 1424 0.0
gi|238908524 hypothetical protein LOC389333 [Homo sapiens] 84 1e-15
gi|169167062 PREDICTED: hypothetical protein LOC285556 [Homo sap... 71 7e-12
gi|113416182 PREDICTED: hypothetical protein LOC285556 [Homo sap... 71 7e-12
gi|113415686 PREDICTED: hypothetical protein LOC285556 [Homo sap... 71 7e-12
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 56 2e-07
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 55 6e-07
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 54 1e-06
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 53 2e-06
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 53 2e-06
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 53 2e-06
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 53 2e-06
gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 53 2e-06
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 51 7e-06
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit... 50 1e-05
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 50 1e-05
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 47 2e-04
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 46 2e-04
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 45 4e-04
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 45 4e-04
gi|163965366 nascent polypeptide-associated complex alpha subuni... 45 5e-04
gi|33667044 ABI gene family, member 3 (NESH) binding protein [Ho... 44 0.001
gi|18079216 CASK interacting protein 1 [Homo sapiens] 44 0.001
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 43 0.002
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 43 0.002
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 43 0.002
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 43 0.002
gi|148806908 fibronectin type III domain containing 1 [Homo sapi... 43 0.002
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 43 0.002
>gi|206597543 hypothetical protein LOC118461 isoform 1 [Homo sapiens]
Length = 1435
Score = 2944 bits (7633), Expect = 0.0
Identities = 1435/1435 (100%), Positives = 1435/1435 (100%)
Query: 1 MMQGNKKCTDAFSDSSSIGSVLDDADREVSSLTDRAFRSLCISEDTSFHDSYLAVSPDIT 60
MMQGNKKCTDAFSDSSSIGSVLDDADREVSSLTDRAFRSLCISEDTSFHDSYLAVSPDIT
Sbjct: 1 MMQGNKKCTDAFSDSSSIGSVLDDADREVSSLTDRAFRSLCISEDTSFHDSYLAVSPDIT 60
Query: 61 RQVFGTFHQRTVGHTQRKSGIWSQLPSQGTEHSGWAATFQQLPKYVQGEEKYPKTSPPPT 120
RQVFGTFHQRTVGHTQRKSGIWSQLPSQGTEHSGWAATFQQLPKYVQGEEKYPKTSPPPT
Sbjct: 61 RQVFGTFHQRTVGHTQRKSGIWSQLPSQGTEHSGWAATFQQLPKYVQGEEKYPKTSPPPT 120
Query: 121 PVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTESQRCESRPTASKPPALKNPPKFAPLP 180
PVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTESQRCESRPTASKPPALKNPPKFAPLP
Sbjct: 121 PVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTESQRCESRPTASKPPALKNPPKFAPLP 180
Query: 181 ENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQESSKNPEMACHGSSSFLPAAN 240
ENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQESSKNPEMACHGSSSFLPAAN
Sbjct: 181 ENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQESSKNPEMACHGSSSFLPAAN 240
Query: 241 DTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENSAFESWNAHQPKLLERKDTAGTVPES 300
DTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENSAFESWNAHQPKLLERKDTAGTVPES
Sbjct: 241 DTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENSAFESWNAHQPKLLERKDTAGTVPES 300
Query: 301 KAPKHYGDTTLLREPCPPERTVSPCQVQASCSQEENRLAAGALSTSIPWGCRDPGAQVFA 360
KAPKHYGDTTLLREPCPPERTVSPCQVQASCSQEENRLAAGALSTSIPWGCRDPGAQVFA
Sbjct: 301 KAPKHYGDTTLLREPCPPERTVSPCQVQASCSQEENRLAAGALSTSIPWGCRDPGAQVFA 360
Query: 361 VEGKAPSSQPDSQEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQ 420
VEGKAPSSQPDSQEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQ
Sbjct: 361 VEGKAPSSQPDSQEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQ 420
Query: 421 FSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQE 480
FSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQE
Sbjct: 421 FSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQE 480
Query: 481 KEPSECQSRDSYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSN 540
KEPSECQSRDSYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSN
Sbjct: 481 KEPSECQSRDSYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSN 540
Query: 541 GVILPNGLEESPPNELSKERPADDPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAKA 600
GVILPNGLEESPPNELSKERPADDPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAKA
Sbjct: 541 GVILPNGLEESPPNELSKERPADDPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAKA 600
Query: 601 PFYVNGEAAERSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPGGAT 660
PFYVNGEAAERSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPGGAT
Sbjct: 601 PFYVNGEAAERSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPGGAT 660
Query: 661 EKMKTHQLENGLSRSVSQETEPEREAGLQNTHLNQKFFPGPLSPEEEDVFYSDSQSDFMP 720
EKMKTHQLENGLSRSVSQETEPEREAGLQNTHLNQKFFPGPLSPEEEDVFYSDSQSDFMP
Sbjct: 661 EKMKTHQLENGLSRSVSQETEPEREAGLQNTHLNQKFFPGPLSPEEEDVFYSDSQSDFMP 720
Query: 721 SLKGKAKFSTSSSDQSFASFDDQQKMWFTENQREDRRKDVSAGDSQKDEKENVMRKDELQ 780
SLKGKAKFSTSSSDQSFASFDDQQKMWFTENQREDRRKDVSAGDSQKDEKENVMRKDELQ
Sbjct: 721 SLKGKAKFSTSSSDQSFASFDDQQKMWFTENQREDRRKDVSAGDSQKDEKENVMRKDELQ 780
Query: 781 YCALSNGHACLENRSQGEALQRERESVSGGRTRKASAEEANFRGSWIGENKGTTFSQAKD 840
YCALSNGHACLENRSQGEALQRERESVSGGRTRKASAEEANFRGSWIGENKGTTFSQAKD
Sbjct: 781 YCALSNGHACLENRSQGEALQRERESVSGGRTRKASAEEANFRGSWIGENKGTTFSQAKD 840
Query: 841 LTPSPSSASNRHMLFTIKDNTLRATPVIKPIMLPLLRTMSLEDSLSSGHKEEELPRPEWG 900
LTPSPSSASNRHMLFTIKDNTLRATPVIKPIMLPLLRTMSLEDSLSSGHKEEELPRPEWG
Sbjct: 841 LTPSPSSASNRHMLFTIKDNTLRATPVIKPIMLPLLRTMSLEDSLSSGHKEEELPRPEWG 900
Query: 901 EDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAPKGNFPS 960
EDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAPKGNFPS
Sbjct: 901 EDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAPKGNFPS 960
Query: 961 MPLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIPTIALPEGDIEDQPPPWQP 1020
MPLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIPTIALPEGDIEDQPPPWQP
Sbjct: 961 MPLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIPTIALPEGDIEDQPPPWQP 1020
Query: 1021 ENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESS 1080
ENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESS
Sbjct: 1021 ENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESS 1080
Query: 1081 QAPGGPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPR 1140
QAPGGPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPR
Sbjct: 1081 QAPGGPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPR 1140
Query: 1141 GSLLDVATSPAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEK 1200
GSLLDVATSPAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEK
Sbjct: 1141 GSLLDVATSPAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEK 1200
Query: 1201 HGESQEGKPCPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGG 1260
HGESQEGKPCPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGG
Sbjct: 1201 HGESQEGKPCPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGG 1260
Query: 1261 PQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPSSEGASP 1320
PQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPSSEGASP
Sbjct: 1261 PQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPSSEGASP 1320
Query: 1321 EPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASAARARTQSVHES 1380
EPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASAARARTQSVHES
Sbjct: 1321 EPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASAARARTQSVHES 1380
Query: 1381 GLQLDPGPHGDCTPHSAGQRPHGPPQSPGEEGVEAPGLGIISTDDLEDFATEGIS 1435
GLQLDPGPHGDCTPHSAGQRPHGPPQSPGEEGVEAPGLGIISTDDLEDFATEGIS
Sbjct: 1381 GLQLDPGPHGDCTPHSAGQRPHGPPQSPGEEGVEAPGLGIISTDDLEDFATEGIS 1435
>gi|49574498 hypothetical protein LOC118461 isoform 2 [Homo sapiens]
Length = 719
Score = 1424 bits (3685), Expect = 0.0
Identities = 692/692 (100%), Positives = 692/692 (100%)
Query: 1 MMQGNKKCTDAFSDSSSIGSVLDDADREVSSLTDRAFRSLCISEDTSFHDSYLAVSPDIT 60
MMQGNKKCTDAFSDSSSIGSVLDDADREVSSLTDRAFRSLCISEDTSFHDSYLAVSPDIT
Sbjct: 1 MMQGNKKCTDAFSDSSSIGSVLDDADREVSSLTDRAFRSLCISEDTSFHDSYLAVSPDIT 60
Query: 61 RQVFGTFHQRTVGHTQRKSGIWSQLPSQGTEHSGWAATFQQLPKYVQGEEKYPKTSPPPT 120
RQVFGTFHQRTVGHTQRKSGIWSQLPSQGTEHSGWAATFQQLPKYVQGEEKYPKTSPPPT
Sbjct: 61 RQVFGTFHQRTVGHTQRKSGIWSQLPSQGTEHSGWAATFQQLPKYVQGEEKYPKTSPPPT 120
Query: 121 PVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTESQRCESRPTASKPPALKNPPKFAPLP 180
PVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTESQRCESRPTASKPPALKNPPKFAPLP
Sbjct: 121 PVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTESQRCESRPTASKPPALKNPPKFAPLP 180
Query: 181 ENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQESSKNPEMACHGSSSFLPAAN 240
ENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQESSKNPEMACHGSSSFLPAAN
Sbjct: 181 ENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQESSKNPEMACHGSSSFLPAAN 240
Query: 241 DTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENSAFESWNAHQPKLLERKDTAGTVPES 300
DTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENSAFESWNAHQPKLLERKDTAGTVPES
Sbjct: 241 DTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENSAFESWNAHQPKLLERKDTAGTVPES 300
Query: 301 KAPKHYGDTTLLREPCPPERTVSPCQVQASCSQEENRLAAGALSTSIPWGCRDPGAQVFA 360
KAPKHYGDTTLLREPCPPERTVSPCQVQASCSQEENRLAAGALSTSIPWGCRDPGAQVFA
Sbjct: 301 KAPKHYGDTTLLREPCPPERTVSPCQVQASCSQEENRLAAGALSTSIPWGCRDPGAQVFA 360
Query: 361 VEGKAPSSQPDSQEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQ 420
VEGKAPSSQPDSQEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQ
Sbjct: 361 VEGKAPSSQPDSQEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQ 420
Query: 421 FSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQE 480
FSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQE
Sbjct: 421 FSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQE 480
Query: 481 KEPSECQSRDSYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSN 540
KEPSECQSRDSYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSN
Sbjct: 481 KEPSECQSRDSYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSN 540
Query: 541 GVILPNGLEESPPNELSKERPADDPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAKA 600
GVILPNGLEESPPNELSKERPADDPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAKA
Sbjct: 541 GVILPNGLEESPPNELSKERPADDPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAKA 600
Query: 601 PFYVNGEAAERSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPGGAT 660
PFYVNGEAAERSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPGGAT
Sbjct: 601 PFYVNGEAAERSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPGGAT 660
Query: 661 EKMKTHQLENGLSRSVSQETEPEREAGLQNTH 692
EKMKTHQLENGLSRSVSQETEPEREAGLQNTH
Sbjct: 661 EKMKTHQLENGLSRSVSQETEPEREAGLQNTH 692
>gi|238908524 hypothetical protein LOC389333 [Homo sapiens]
Length = 1015
Score = 83.6 bits (205), Expect = 1e-15
Identities = 115/463 (24%), Positives = 166/463 (35%), Gaps = 71/463 (15%)
Query: 917 STPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAPKGNFPSMPLVGEGDRVKAPPDA 976
S P T ++ + + D G S E + P P G+ P VG D K P
Sbjct: 552 SAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHP----VGTLDADKCPEVL 607
Query: 977 APGLVASNCKSGSA----DSGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFK 1032
PG AS + D KL + P P G P + C EE G +
Sbjct: 608 GPGEAASGRPRMAIPRPRDVRKLVKTTYAP--GFPAGAQGSGLPAPPADPCGEE---GGE 662
Query: 1033 SHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPGGPELLPEE 1092
S P GPP S P P P+ + ++SQ P G E
Sbjct: 663 SKTQEPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQ-PNGVLRRRAE 721
Query: 1093 PNQASPWASSS-----PARVTRREDLTHALVWEGGSDPLLELSAEDL------RTLSPRG 1141
+ A P+ + + RR ++T + G ++ A+ L RT G
Sbjct: 722 NSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGG 781
Query: 1142 SLLDVATSPAGTSG-RLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEK 1200
+ SP G +G R P + AS P + PK + + A+ +
Sbjct: 782 ARSSSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQA-------- 833
Query: 1201 HGESQEGKPCPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGG 1260
P P + PL R P S PP S S+ R+PG
Sbjct: 834 --------PLPRE-------PLALAGRTAPAQPRAASAPPT--DRSPQSPSQGARRQPGA 876
Query: 1261 PQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPSSEGASP 1320
PL KVL DP+SG Y+ + P Q +++ +DPE+G+YV+V +P S
Sbjct: 877 ----APLG------KVLVDPESGRYYFVEAPRQPRLRVLFDPESGQYVEVLLPPS----- 921
Query: 1321 EPPPPDALAAPYVL-----YPGFQPVPVTALMPLRCSSQLSAP 1358
P PP + P L P + P+P +L P L +P
Sbjct: 922 SPGPPHRVYTPLALGLGLYPPAYGPIPSLSLPPSPGPQALGSP 964
Score = 33.1 bits (74), Expect = 2.0
Identities = 39/158 (24%), Positives = 57/158 (36%), Gaps = 34/158 (21%)
Query: 959 PSMPLVGEGDRV----KAPPDAAPGL-------VASNCKSGSADSGKLAAPWHIPTIALP 1007
PS P++ + ++ ++P AP L VA + S+ S PW P
Sbjct: 453 PSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEPRSSPSPPAFFPWEAP----- 507
Query: 1008 EGDIEDQP-PPW--QPENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGE 1064
D+P W P+ W+ PG F + G L P P P +PG
Sbjct: 508 -----DRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELAP------PTPSAPGT 556
Query: 1065 SSACSPAASNIWEESSQAPGG----PELLPEEPNQASP 1098
+ + E S A GG PE+ EP + P
Sbjct: 557 PEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHP 594
>gi|169167062 PREDICTED: hypothetical protein LOC285556 [Homo sapiens]
Length = 1826
Score = 71.2 bits (173), Expect = 7e-12
Identities = 92/346 (26%), Positives = 139/346 (40%), Gaps = 64/346 (18%)
Query: 1043 PPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQA---PGGPELLPEEPNQASPW 1099
PP + V + P P P + + +AS+I + A P GP PE P+ A
Sbjct: 1406 PPVHKDVERTQPLQPLPPLPSNRNVFTVSASSIQKTGGVAGKFPQGPS--PESPSAAKGI 1463
Query: 1100 ASS-------SPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAG 1152
S SPA +++T+ + GS+ LE S D + L + +
Sbjct: 1464 KSQGLRSLKISPATRAPPDEVTNR---KSGSN--LEKSNSDCE------NYLTIPLKGSS 1512
Query: 1153 TSGRLELPAQLERTASKPPAV---PPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKP 1209
+G L S+P A PP + A + S R + + + S +P
Sbjct: 1513 AAGEL---------LSRPGASREGPPNSSAATLCSLPPLSARSQVPSSSKGSQVSGTSRP 1563
Query: 1210 C----PEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVH-----RHSVSGFSEPVGRRPGG 1260
P++ +T P P+ P H + PP + V FS P P
Sbjct: 1564 AWRTKPDNPRETVAAPPGPQS-PEHPPTTIYHQPPLPFTLQGAQPQVLCFSPPSMPAPA- 1621
Query: 1261 PQSLTPLPAYPATQ--------KVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSI 1312
P + P+P P Q K+L D +G+Y++ D P+Q + +DPETG+YV V +
Sbjct: 1622 PAASAPVPTDPFQQAQPQQTQRKMLLDVTTGQYYLVDTPVQPMTRRLFDPETGQYVDVPM 1681
Query: 1313 PSSEGA----SPEPPP----PDALAAPYVLYPGFQP--VPVTALMP 1348
S + A S PP P A Y++YPGF P +P AL P
Sbjct: 1682 TSQQQAVAPMSISVPPLALSPGAYGPTYMIYPGFLPTVLPTNALQP 1727
Score = 42.7 bits (99), Expect = 0.002
Identities = 125/579 (21%), Positives = 203/579 (35%), Gaps = 108/579 (18%)
Query: 6 KKCTDAFSDSSSIGSVLDDADREVSSLTDRAFRSLCISEDTSFHDSYLAVSPDITRQVFG 65
K+ D S +SS S LDDAD+EV +LT RAFRSL + + S S ++ FG
Sbjct: 633 KELVDYSSGASSAVSELDDADKEVRNLTSRAFRSLAYPYFEALNISSRESSTTLSEVGFG 692
Query: 66 TFHQ------RTVGHTQRKSGIWSQLPSQGT---EHSGWAATFQQLPKYVQGEEKYPKTS 116
+ VG +S + S S + SG AT QL Y+Q ++ K
Sbjct: 693 RWSTFLDLKCGGVGARVEQSLLRSSAASVAAGLRKGSGARATADQL--YIQSKKSQTKA- 749
Query: 117 PPPTPVQRRLEVPVSGLRSSNKPV-------------SKVSTLIKSFDRTESQRCESRPT 163
LE VS + K V S+V TL++ + + S P
Sbjct: 750 ---------LEFVVSKVEGEIKHVETPLCFQKQVQTGSRVVTLLEPLNVRSESKASSAPG 800
Query: 164 ASKPPALKNPPKFAPLPENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQESSK 223
+ A K P K SA+ + S T + S R G Q+S
Sbjct: 801 PGR--ATKGPGKGP-----------GSAYTD------DGSETSEGSKPTSRADGPQKSKF 841
Query: 224 NPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRG-KGTFLHSENSAFESWNA 282
+ + S + ++ + HH T + G +G+ E +
Sbjct: 842 ASSLLKNVISKKMQREHEFKMERGEVMDTSHHLSGTSKETEGARGSERQRERGLQRQSSR 901
Query: 283 H-----QPKLLERKDTA--GTVPESKAPKHYGDTTLLREPCP----PERTVSPCQVQASC 331
H + ++ D G+V SK+P T R P + C+++ S
Sbjct: 902 HSEAGSEYTVVSMSDAGGEGSVAGSKSPVFKASTPRERNAGPGRNFTDGHTEVCEIKKSA 961
Query: 332 SQEENRLAAGALSTSI-PWGCRDPGAQVFAVEGKAPSSQPDSQEKPAQPPWRKPKTGKKG 390
S+ + + +++ W + +++++ Q P K K K G
Sbjct: 962 SETVKGIFLRSQNSAFRSW------------------KEKEAEKREEQAPIGKLKLPKGG 1003
Query: 391 --KESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLP---------VEPN----- 434
+ L + K R + P+++ A P + P
Sbjct: 1004 DWRADLGEISASKNTIMSRLFVPNIQQTPKDKQPRKQATKYPAAQATSTAVIRPKAPEIK 1063
Query: 435 ------EHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQS 488
+ FNI+KLLTP + A + + + + G ++ Q
Sbjct: 1064 IRLGSVQQPSSDFNIAKLLTPKLAGGSA-SNLFKTIEDNSRAQQKLFRGDNLEKVPHFQV 1122
Query: 489 RD-SYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEK 526
RD KSKA L ++DVRK +K + SS V E+
Sbjct: 1123 RDIRDKSKAQGPLHQVRDVRKLIKGSGDSSDKGSVTPEQ 1161
>gi|113416182 PREDICTED: hypothetical protein LOC285556 [Homo sapiens]
Length = 1826
Score = 71.2 bits (173), Expect = 7e-12
Identities = 92/346 (26%), Positives = 139/346 (40%), Gaps = 64/346 (18%)
Query: 1043 PPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQA---PGGPELLPEEPNQASPW 1099
PP + V + P P P + + +AS+I + A P GP PE P+ A
Sbjct: 1406 PPVHKDVERTQPLQPLPPLPSNRNVFTVSASSIQKTGGVAGKFPQGPS--PESPSAAKGI 1463
Query: 1100 ASS-------SPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAG 1152
S SPA +++T+ + GS+ LE S D + L + +
Sbjct: 1464 KSQGLRSLKISPATRAPPDEVTNR---KSGSN--LEKSNSDCE------NYLTIPLKGSS 1512
Query: 1153 TSGRLELPAQLERTASKPPAV---PPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKP 1209
+G L S+P A PP + A + S R + + + S +P
Sbjct: 1513 AAGEL---------LSRPGASREGPPNSSAATLCSLPPLSARSQVPSSSKGSQVSGTSRP 1563
Query: 1210 C----PEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVH-----RHSVSGFSEPVGRRPGG 1260
P++ +T P P+ P H + PP + V FS P P
Sbjct: 1564 AWRTKPDNPRETVAAPPGPQS-PEHPPTTIYHQPPLPFTLQGAQPQVLCFSPPSMPAPA- 1621
Query: 1261 PQSLTPLPAYPATQ--------KVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSI 1312
P + P+P P Q K+L D +G+Y++ D P+Q + +DPETG+YV V +
Sbjct: 1622 PAASAPVPTDPFQQAQPQQTQRKMLLDVTTGQYYLVDTPVQPMTRRLFDPETGQYVDVPM 1681
Query: 1313 PSSEGA----SPEPPP----PDALAAPYVLYPGFQP--VPVTALMP 1348
S + A S PP P A Y++YPGF P +P AL P
Sbjct: 1682 TSQQQAVAPMSISVPPLALSPGAYGPTYMIYPGFLPTVLPTNALQP 1727
Score = 42.7 bits (99), Expect = 0.002
Identities = 125/579 (21%), Positives = 203/579 (35%), Gaps = 108/579 (18%)
Query: 6 KKCTDAFSDSSSIGSVLDDADREVSSLTDRAFRSLCISEDTSFHDSYLAVSPDITRQVFG 65
K+ D S +SS S LDDAD+EV +LT RAFRSL + + S S ++ FG
Sbjct: 633 KELVDYSSGASSAVSELDDADKEVRNLTSRAFRSLAYPYFEALNISSRESSTTLSEVGFG 692
Query: 66 TFHQ------RTVGHTQRKSGIWSQLPSQGT---EHSGWAATFQQLPKYVQGEEKYPKTS 116
+ VG +S + S S + SG AT QL Y+Q ++ K
Sbjct: 693 RWSTFLDLKCGGVGARVEQSLLRSSAASVAAGLRKGSGARATADQL--YIQSKKSQTKA- 749
Query: 117 PPPTPVQRRLEVPVSGLRSSNKPV-------------SKVSTLIKSFDRTESQRCESRPT 163
LE VS + K V S+V TL++ + + S P
Sbjct: 750 ---------LEFVVSKVEGEIKHVETPLCFQKQVQTGSRVVTLLEPLNVRSESKASSAPG 800
Query: 164 ASKPPALKNPPKFAPLPENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQESSK 223
+ A K P K SA+ + S T + S R G Q+S
Sbjct: 801 PGR--ATKGPGKGP-----------GSAYTD------DGSETSEGSKPTSRADGPQKSKF 841
Query: 224 NPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRG-KGTFLHSENSAFESWNA 282
+ + S + ++ + HH T + G +G+ E +
Sbjct: 842 ASSLLKNVISKKMQREHEFKMERGEVMDTSHHLSGTSKETEGARGSERQRERGLQRQSSR 901
Query: 283 H-----QPKLLERKDTA--GTVPESKAPKHYGDTTLLREPCP----PERTVSPCQVQASC 331
H + ++ D G+V SK+P T R P + C+++ S
Sbjct: 902 HSEAGSEYTVVSMSDAGGEGSVAGSKSPVFKASTPRERNAGPGRNFTDGHTEVCEIKKSA 961
Query: 332 SQEENRLAAGALSTSI-PWGCRDPGAQVFAVEGKAPSSQPDSQEKPAQPPWRKPKTGKKG 390
S+ + + +++ W + +++++ Q P K K K G
Sbjct: 962 SETVKGIFLRSQNSAFRSW------------------KEKEAEKREEQAPIGKLKLPKGG 1003
Query: 391 --KESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLP---------VEPN----- 434
+ L + K R + P+++ A P + P
Sbjct: 1004 DWRADLGEISASKNTIMSRLFVPNIQQTPKDKQPRKQATKYPAAQATSTAVIRPKAPEIK 1063
Query: 435 ------EHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQS 488
+ FNI+KLLTP + A + + + + G ++ Q
Sbjct: 1064 IRLGSVQQPSSDFNIAKLLTPKLAGGSA-SNLFKTIEDNSRAQQKLFRGDNLEKVPHFQV 1122
Query: 489 RD-SYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEK 526
RD KSKA L ++DVRK +K + SS V E+
Sbjct: 1123 RDIRDKSKAQGPLHQVRDVRKLIKGSGDSSDKGSVTPEQ 1161
>gi|113415686 PREDICTED: hypothetical protein LOC285556 [Homo sapiens]
Length = 1826
Score = 71.2 bits (173), Expect = 7e-12
Identities = 92/346 (26%), Positives = 139/346 (40%), Gaps = 64/346 (18%)
Query: 1043 PPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQA---PGGPELLPEEPNQASPW 1099
PP + V + P P P + + +AS+I + A P GP PE P+ A
Sbjct: 1406 PPVHKDVERTQPLQPLPPLPSNRNVFTVSASSIQKTGGVAGKFPQGPS--PESPSAAKGI 1463
Query: 1100 ASS-------SPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAG 1152
S SPA +++T+ + GS+ LE S D + L + +
Sbjct: 1464 KSQGLRSLKISPATRAPPDEVTNR---KSGSN--LEKSNSDCE------NYLTIPLKGSS 1512
Query: 1153 TSGRLELPAQLERTASKPPAV---PPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKP 1209
+G L S+P A PP + A + S R + + + S +P
Sbjct: 1513 AAGEL---------LSRPGASREGPPNSSAATLCSLPPLSARSQVPSSSKGSQVSGTSRP 1563
Query: 1210 C----PEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVH-----RHSVSGFSEPVGRRPGG 1260
P++ +T P P+ P H + PP + V FS P P
Sbjct: 1564 AWRTKPDNPRETVAAPPGPQS-PEHPPTTIYHQPPLPFTLQGAQPQVLCFSPPSMPAPA- 1621
Query: 1261 PQSLTPLPAYPATQ--------KVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSI 1312
P + P+P P Q K+L D +G+Y++ D P+Q + +DPETG+YV V +
Sbjct: 1622 PAASAPVPTDPFQQAQPQQTQRKMLLDVTTGQYYLVDTPVQPMTRRLFDPETGQYVDVPM 1681
Query: 1313 PSSEGA----SPEPPP----PDALAAPYVLYPGFQP--VPVTALMP 1348
S + A S PP P A Y++YPGF P +P AL P
Sbjct: 1682 TSQQQAVAPMSISVPPLALSPGAYGPTYMIYPGFLPTVLPTNALQP 1727
Score = 42.7 bits (99), Expect = 0.002
Identities = 125/579 (21%), Positives = 203/579 (35%), Gaps = 108/579 (18%)
Query: 6 KKCTDAFSDSSSIGSVLDDADREVSSLTDRAFRSLCISEDTSFHDSYLAVSPDITRQVFG 65
K+ D S +SS S LDDAD+EV +LT RAFRSL + + S S ++ FG
Sbjct: 633 KELVDYSSGASSAVSELDDADKEVRNLTSRAFRSLAYPYFEALNISSRESSTTLSEVGFG 692
Query: 66 TFHQ------RTVGHTQRKSGIWSQLPSQGT---EHSGWAATFQQLPKYVQGEEKYPKTS 116
+ VG +S + S S + SG AT QL Y+Q ++ K
Sbjct: 693 RWSTFLDLKCGGVGARVEQSLLRSSAASVAAGLRKGSGARATADQL--YIQSKKSQTKA- 749
Query: 117 PPPTPVQRRLEVPVSGLRSSNKPV-------------SKVSTLIKSFDRTESQRCESRPT 163
LE VS + K V S+V TL++ + + S P
Sbjct: 750 ---------LEFVVSKVEGEIKHVETPLCFQKQVQTGSRVVTLLEPLNVRSESKASSAPG 800
Query: 164 ASKPPALKNPPKFAPLPENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQESSK 223
+ A K P K SA+ + S T + S R G Q+S
Sbjct: 801 PGR--ATKGPGKGP-----------GSAYTD------DGSETSEGSKPTSRADGPQKSKF 841
Query: 224 NPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRG-KGTFLHSENSAFESWNA 282
+ + S + ++ + HH T + G +G+ E +
Sbjct: 842 ASSLLKNVISKKMQREHEFKMERGEVMDTSHHLSGTSKETEGARGSERQRERGLQRQSSR 901
Query: 283 H-----QPKLLERKDTA--GTVPESKAPKHYGDTTLLREPCP----PERTVSPCQVQASC 331
H + ++ D G+V SK+P T R P + C+++ S
Sbjct: 902 HSEAGSEYTVVSMSDAGGEGSVAGSKSPVFKASTPRERNAGPGRNFTDGHTEVCEIKKSA 961
Query: 332 SQEENRLAAGALSTSI-PWGCRDPGAQVFAVEGKAPSSQPDSQEKPAQPPWRKPKTGKKG 390
S+ + + +++ W + +++++ Q P K K K G
Sbjct: 962 SETVKGIFLRSQNSAFRSW------------------KEKEAEKREEQAPIGKLKLPKGG 1003
Query: 391 --KESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLP---------VEPN----- 434
+ L + K R + P+++ A P + P
Sbjct: 1004 DWRADLGEISASKNTIMSRLFVPNIQQTPKDKQPRKQATKYPAAQATSTAVIRPKAPEIK 1063
Query: 435 ------EHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQS 488
+ FNI+KLLTP + A + + + + G ++ Q
Sbjct: 1064 IRLGSVQQPSSDFNIAKLLTPKLAGGSA-SNLFKTIEDNSRAQQKLFRGDNLEKVPHFQV 1122
Query: 489 RD-SYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEK 526
RD KSKA L ++DVRK +K + SS V E+
Sbjct: 1123 RDIRDKSKAQGPLHQVRDVRKLIKGSGDSSDKGSVTPEQ 1161
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 56.2 bits (134), Expect = 2e-07
Identities = 112/508 (22%), Positives = 190/508 (37%), Gaps = 67/508 (13%)
Query: 212 PGRKHGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGE---PGRGKGT 268
P K E+E +K+P + PA + + E+K P PV E P K
Sbjct: 562 PEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSP 621
Query: 269 FLHSENSAFESWNAHQPKLLERKDTAGTVPESKAPKHYGDTTLLREPCPPERTVSPCQVQ 328
S E + + K K+ A + ++K+P+ E PE+ SP + +
Sbjct: 622 VKEEAKSPAEVKSPEKAK-SPTKEEAKSPEKAKSPEK-------EEAKSPEKAKSPVKAE 673
Query: 329 ASCSQEENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPSSQPDSQEKPAQPPWRKPKTGK 388
A S E+ + A + S P + P + E K+P EK P + K+ +
Sbjct: 674 AK-SPEKAKSPVKAEAKS-PEKAKSPVKE----EAKSP-------EKAKSPVKEEAKSPE 720
Query: 389 KGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISKLLT 448
K K +++ E KT + P +P++ S A L V+ E P
Sbjct: 721 KAKSPVKE--EAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTP--------- 769
Query: 449 PIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLK-DVR 507
+ A AD P E+ SP + + K P + +S +KAP K +V+
Sbjct: 770 ---AKEEARSPADKFP-EKAKSPVKE----EVKSPEKAKSPLKEDAKAPEKEIPKKEEVK 821
Query: 508 KRVKSTYS------SSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESPPNELSKERP 561
VK P K +EK +++ S P P E KE
Sbjct: 822 SPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPA 881
Query: 562 ADDPTASHINPQKDPTADPSE-PSADSYLTLSTAPTIAKAPFYVNGEAAERSSYENKEVE 620
+ P S + +K+ D + P+ + AP AK + + E++ KE +
Sbjct: 882 VEKPKESKVEAKKEEAEDKKKVPTPE-----KEAP--AKVEVKEDAKPKEKTEVAKKEPD 934
Query: 621 GELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPGGATEKMKTHQLENGLSRSVSQE- 679
P+ + + +E P K + + PE EK KT +++S+E
Sbjct: 935 DAKAKEPSKPA---EKKEAAPEKKDTKEEKAKKPE-----EKPKTEAKAKEDDKTLSKEP 986
Query: 680 TEPEREAGLQNTHLNQKFFPGPLSPEEE 707
++P+ E +++ +QK P E+
Sbjct: 987 SKPKAEKAEKSSSTDQKDSKPPEKATED 1014
Score = 35.4 bits (80), Expect = 0.40
Identities = 62/327 (18%), Positives = 125/327 (38%), Gaps = 44/327 (13%)
Query: 371 DSQEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLP 430
+ +EK A+ K + G G+E + EE+T++ PP +P+++ +++ +
Sbjct: 472 EEEEKEAKEEEGKEEEG--GEEEEAEGGEEETKS----PPAEEAASPEKE-AKSPVKEEA 524
Query: 431 VEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRD 490
P E P +K + + + A S E SPP + +E+ S + +
Sbjct: 525 KSPAEAKSPEKEEAKSPAEV----KSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKS 580
Query: 491 SYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEE 550
K+K+P+ K+ K S + E+ + + K PV E
Sbjct: 581 PEKAKSPA-----KEEAKSPAEAKSPEKAKSPVKEEAKSPAEAK-SPVKE--------EA 626
Query: 551 SPPNELSKERPADDPTASHI-------NPQKDPTADPSEPSADSYLTLSTAPTIAKAPFY 603
P E+ A PT +P+K+ P E + + +P AK+P
Sbjct: 627 KSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSP-EKAKSPVKAEAKSPEKAKSPVK 685
Query: 604 VNGEAAERSSYENKE-----------VEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNR 652
++ E++ KE V+ E + S + + + ++ +
Sbjct: 686 AEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAK 745
Query: 653 DPEPGGATEKMKTHQLENGLSRSVSQE 679
PE + EK KT +++ +++ ++E
Sbjct: 746 SPEKAKSPEKAKTLDVKSPEAKTPAKE 772
Score = 31.6 bits (70), Expect = 5.7
Identities = 87/482 (18%), Positives = 163/482 (33%), Gaps = 50/482 (10%)
Query: 761 SAGDSQKDEKENVMRKDELQYCALSNGHACLENRSQGEALQRERESV-------SGGRTR 813
S +++ EKE E++ + A E +S EA E+E S + +
Sbjct: 526 SPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAK 585
Query: 814 KASAEEANFRGSWIGENKGTTFSQAKDLTPSPSSASNRHMLFTIKDNTLRATPVIKP--I 871
+ EEA K S K+ SP+ A + +K+ V P
Sbjct: 586 SPAKEEAKSPAEAKSPEKAK--SPVKEEAKSPAEAKS-----PVKEEAKSPAEVKSPEKA 638
Query: 872 MLPLLRTMSLEDSLSSGHKEEELPRPEWGEDPGFCAPENQDILGTSTPTNTRGT-RVKCM 930
P + S KEE PE + P ++ + + + + K
Sbjct: 639 KSPTKEEAKSPEKAKSPEKEEA-KSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSP 697
Query: 931 ANEVMEDPGQGSSMARMEASQPAPKGNFPSMPLVGEGDRVKAPPDAAPGLVASNCKSGSA 990
E + P + S + EA P K P ++ K+P K +
Sbjct: 698 VKEEAKSPEKAKSPVKEEAKSPE-KAKSPVKEEAKTPEKAKSP-----------VKEEAK 745
Query: 991 DSGKLAAPWHIPTIAL--PEGDIEDQPPPWQPENCWEEQTPG-FKSHFLSTPRAGPPGRR 1047
K +P T+ + PE + P + + E+ K S +A P +
Sbjct: 746 SPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLK- 804
Query: 1048 LVPSERANSPNPGSPGESSACSPAASNIWEESSQAPGGPELLPEEPNQASPWASSSPARV 1107
E A +P P + SP + + P+ EE A+P + +
Sbjct: 805 ----EDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATP--KTEEKKD 858
Query: 1108 TRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELPAQLERTA 1167
+++E+ + P +E E P+ S ++ A ++ P +
Sbjct: 859 SKKEEAPK----KEAPKPKVEEKKEPA-VEKPKESKVEAKKEEAEDKKKVPTPEK----- 908
Query: 1168 SKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRER 1227
P V K + + ++A K +A+E +++ + PE + +++ P E+
Sbjct: 909 EAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEK 968
Query: 1228 PR 1229
P+
Sbjct: 969 PK 970
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 54.7 bits (130), Expect = 6e-07
Identities = 131/560 (23%), Positives = 204/560 (36%), Gaps = 84/560 (15%)
Query: 123 QRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTESQRCESRPTASKPPALKNPPKFAP--LP 180
Q + + S SN S L ++S+ +S T KPP+ PP AP LP
Sbjct: 400 QNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPS-APQSLP 458
Query: 181 ENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQESSKNPEMACHGSSSFLPAAN 240
E + SA +E ++ +S + +S +N + P N
Sbjct: 459 EPVASAHSSSA-------ESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTN 511
Query: 241 ----DTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENSAFESWNAHQPKLLERKDTAGT 296
D S+ +P P + EP R S +SA ++ + +
Sbjct: 512 KWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAP 571
Query: 297 VPESKAPKHYGDTTLLREPC---PPER-TVSPCQ----VQASCSQEENRLAAGALSTS-I 347
+AP H G + + P PP+R TV Q V+AS G +
Sbjct: 572 RAPPEAP-HPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLL 630
Query: 348 PWGCRDPGAQ---VFAVEGKAPSSQPDSQEKPAQPPWRKPKTGK----------KGKESL 394
P+G RD ++ +G+ P + ++ KPA PP + K K G E
Sbjct: 631 PYGSRDQTSKDKPKVKTKGR-PRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPA 689
Query: 395 QDTLEEKTQ--------TNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDP---PFNI 443
+D +E++T T +GPP H+ + + V+ + D P
Sbjct: 690 KDNVEDRTPEHFALVPLTESQGPP----HSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRD 745
Query: 444 SKLLTPI---IPSKHALDSADSQPAERTPSPPG---QLNGYQEKEP-------SECQSRD 490
+KLL+P+ P + + R P PPG + ++K+P SE +S D
Sbjct: 746 TKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSD 805
Query: 491 S-------YKSKAPSLLFNLK-DVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGV 542
S K +A N K + K +KS SSS KT+ Q S
Sbjct: 806 SSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQS--SKKE 863
Query: 543 ILPNGLEESPPNELSKERPADDPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAKAPF 602
+LP PP S ++PA P + D SA S + +I K
Sbjct: 864 MLP-----PPPVSSSSQKPA-KPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQR- 916
Query: 603 YVNGEAAERSSYENKEVEGE 622
V G+ + RSS E+K G+
Sbjct: 917 RVEGKGS-RSSSEHKGSSGD 935
Score = 38.9 bits (89), Expect = 0.036
Identities = 110/535 (20%), Positives = 188/535 (35%), Gaps = 104/535 (19%)
Query: 113 PKTSPPPTPVQ-RRLEVPVSGLRSSNKPVSKV----STLIKSFDRTESQRCESRPTASKP 167
P SP V+ E P L + +P S+ S KS + RP +
Sbjct: 242 PAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQD 301
Query: 168 PALKNPPKFAPLPENSVNFCFD--------SAFLTVRRVPAE-VSNTHQNSYQPGRKHGE 218
A P+ PLPE+ F+ A LT ++P++ V T+ N H
Sbjct: 302 QAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEV-----HCV 356
Query: 219 QESSKNPEMACHGSSSFLPAANDTATLCESKFPSP----HHKPVTGEPGRGKGTFLHSEN 274
+E K EM H L A + +T SKFP P H + + T + +
Sbjct: 357 EEILK--EMT-HSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHS 413
Query: 275 SAFESWNAHQPKLLERKDTAGTVPESKAPKHYGDTTLLREPCPPERTVSPCQVQASCSQE 334
++ + ++ L+ D+ + E K + P P+ P A S
Sbjct: 414 NSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSA---PPSAPQSLPEPV-ASAHSSSA 469
Query: 335 ENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPSSQPDSQE-KPAQPPWRKPKTGKKGKES 393
E+ + + S+S + ++ SS DS+E +P + P +P+ K
Sbjct: 470 ESESTSDSDSSS---------------DSESESSSSDSEENEPLETPAPEPEPPTTNKWQ 514
Query: 394 LQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISKLLTPIIPS 453
L + L + +Q P P+ EP + S
Sbjct: 515 LDNWLTKVSQ------PAAPPEGPRS-----------TEPPRRHP-------------ES 544
Query: 454 KHALDSADSQPAERTPSPPGQLNGYQEKEPSE--------CQSRDSYKSKAPSLLFNLKD 505
K + DSA SQ + PP + + + P E CQ + + K
Sbjct: 545 KGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQ 604
Query: 506 VRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESPPNELSKERPADDP 565
+K VK++ + +R + G++EP +LP G + + K + P
Sbjct: 605 PKKPVKASARAG---------SRTSLQGEREP----GLLPYGSRDQTSKDKPKVKTKGRP 651
Query: 566 TASHINPQKDPTADPSEPSADSYLTLSTAPTIAKAPFYVNGEAAERSSYENKEVE 620
A+ N K PS++ S+ P +KA ++G + + E++ E
Sbjct: 652 RAAASNEPKPAV----PPSSEKKKHKSSLPAPSKA---LSGPEPAKDNVEDRTPE 699
Score = 31.6 bits (70), Expect = 5.7
Identities = 54/261 (20%), Positives = 94/261 (36%), Gaps = 23/261 (8%)
Query: 1043 PPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPGGPELLPEEPNQASPWASS 1102
PP PS + P P + SS+ +++ + SS + E N+ +
Sbjct: 444 PPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAP 503
Query: 1103 SPARVTRRE---DLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLEL 1159
P T + D V + + P S E R D ATS + +
Sbjct: 504 EPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPP 563
Query: 1160 PAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKPCP-------- 1211
P +++SK P PP+ +R+ + + +++ Q Q G Q KP
Sbjct: 564 P----KSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTV-GTKQPKKPVKASARAGSR 618
Query: 1212 EDLEQTQQRPLCP---RERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLP 1268
L+ ++ L P R++ + P V++ P + +EP P +
Sbjct: 619 TSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRP----RAAASNEPKPAVPPSSEKKKHKS 674
Query: 1269 AYPATQKVLQDPQSGEYFVFD 1289
+ PA K L P+ + V D
Sbjct: 675 SLPAPSKALSGPEPAKDNVED 695
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 53.9 bits (128), Expect = 1e-06
Identities = 96/399 (24%), Positives = 150/399 (37%), Gaps = 55/399 (13%)
Query: 1038 TPRAGPPGRRLVPS---ERANSPNPGSPGESSACSPAASNIWEESSQAPGGPELLPEEPN 1094
+PR P RR+ P R+ SP S++ S ++S+ S++P P++P
Sbjct: 322 SPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSP------PKKP- 374
Query: 1095 QASPWASSSPARVTRREDLT-------HALVWEGGSDPLLELSAEDLRTLSPRGSLLDVA 1147
P +SSP R TRR + H P S ++ R S + V
Sbjct: 375 ---PKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSV- 430
Query: 1148 TSPAGTSGRLELPAQLERTASKPPAVPPK----TEKALRRAKKLAS----KRRKTDQAQE 1199
SP TSG++ E+ S PA P+ +E + K+A+ ++R+ + Q
Sbjct: 431 -SPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQN 489
Query: 1200 KHGESQEGKPCPEDLEQTQQRPLCPRE--RPRHNFPVVRSLPPPVHRHSVSGFSEPVGRR 1257
+ S G + E+ ++ + E R R + P + P P R + P GRR
Sbjct: 490 QQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKE---TSPRGRR 546
Query: 1258 PGGP------QSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQ--VKIKTFYDPETGKYVK 1309
P + +P PA P ++ P P + + + P +Y
Sbjct: 547 RRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSP 606
Query: 1310 VSIPSSEGASPEPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASA 1369
P ASP PPPP A+P P P + Q S+P R+ P S+
Sbjct: 607 SPPPKRRTASP-PPPPKRRASP-------SPPPKRRVSHSPPPKQRSSPVTKRRSPSLSS 658
Query: 1370 ARARTQSVHESGLQL-DPGPHGDCTPHSAGQRPHGPPQS 1407
+ S S + P P+ HS RP P S
Sbjct: 659 KHRKGSSPSRSTREARSPQPN---KRHSPSPRPRAPQTS 694
Score = 44.3 bits (103), Expect = 9e-04
Identities = 159/721 (22%), Positives = 231/721 (32%), Gaps = 149/721 (20%)
Query: 742 DQQKMWFTENQREDRRKDVSAGDSQKDEKENVMRKDELQYCALSNGHACLENRSQGEALQ 801
+Q+K+ + Q ED+ K K+EKE+ K E R + ++
Sbjct: 137 EQEKLASMKKQDEDKDK------RDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVR 190
Query: 802 RERESVSGGRTRKASAEEANFRGSWIGENKGTTFSQAKDLTPSPSSASNRHMLFTIKDNT 861
RER+ R + + + + K+ TP S + ++++ T
Sbjct: 191 RERKRSHSRSPRHRTKSRSP-----------SPAPEKKEKTPELPEPSVKVKEPSVQEAT 239
Query: 862 LRAT--PVIKPIMLPLLRTMSLEDSLSSGHKEEELPRPEWGEDPGFCAPENQDILGTSTP 919
+ V KP +P + S E + S KE+E RP +++ + +P
Sbjct: 240 STSDILKVPKPEPIPEPKEPSPEKN-SKKEKEKEKTRPR-----SRSRSKSRSRTRSRSP 293
Query: 920 TNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAPKGNFPS--MPLVGEGDRVKAPPDAA 977
++TR R + + P + S R +P+P+ P MP R ++P
Sbjct: 294 SHTRPRR-RHRSRSRSYSPRRRPSPRR----RPSPRRRTPPRRMPPPPRHRRSRSPVRRR 348
Query: 978 PGLVASNCKSGSADSGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFKSHFLS 1037
AS S S+ S + PP +P +P K+ LS
Sbjct: 349 RRSSASLSGSSSSSSSS-----------------RSRSPPKKPPK--RTSSPPRKTRRLS 389
Query: 1038 TPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEES--SQAPGGPELLPEEPNQ 1095
P A PP RR PS A P P + +P SN +S S +PG +
Sbjct: 390 -PSASPPRRRHRPSPPATPP----PKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKG 444
Query: 1096 ASPWASSSPARVTRREDLTHALVWEGG----------------------SDPLLELSAED 1133
S SPA R+ +L+ + +GG SD S+ED
Sbjct: 445 TEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSED 504
Query: 1134 ---------------------LRTLSPRGSLLDVATSPAGTSGRLELPAQLERTASKPPA 1172
R+ SP TSP G R P R S PA
Sbjct: 505 ERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPA 564
Query: 1173 VPPK-----TEKALRRAKKLASKRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRER 1227
PP+ T RR +RR + + P P +T P P+ R
Sbjct: 565 PPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRR 624
Query: 1228 PRHNFPVVRSL---PPPVHRHSV--------------SGFS------EPVGRRPGGPQSL 1264
+ P R + PPP R S G S E +P S
Sbjct: 625 ASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSP 684
Query: 1265 TPLPAYPATQK--------VLQDPQSGEY---------FVFDLPLQVKIKTFYDPETGKY 1307
+P P P T PQ + V P KIK P
Sbjct: 685 SPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSV 744
Query: 1308 VKVSIPSSEGASPEPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRA 1367
+VS S SPEP A P P P T P + +PT PR
Sbjct: 745 RRVSSSRSVSGSPEPAAKKPPAPP---SPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRN 801
Query: 1368 S 1368
S
Sbjct: 802 S 802
Score = 43.1 bits (100), Expect = 0.002
Identities = 115/519 (22%), Positives = 175/519 (33%), Gaps = 96/519 (18%)
Query: 113 PKTSPPP-------TPVQRRLE--VPVSGLRSSNKPVSKVSTLIKSFDRTESQRCESR-- 161
P+ PPP +PV+RR +SG SS+ S K RT S ++R
Sbjct: 329 PRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRL 388
Query: 162 -PTASKP-------PALKNPPK--FAPLPENSVNFCFDSAFLTVRRVPAEVSN----THQ 207
P+AS P P PPK +P P+ S ++ R +V+ +
Sbjct: 389 SPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKR 448
Query: 208 NSYQPGRKH-----GEQESSKNPEMACHGS--------SSFLPAANDTATLCESKFPSPH 254
S P K E E K +MA S +++D+ + S+ P
Sbjct: 449 ESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPK 508
Query: 255 HKPV-TGEPGRGKGTFLHSENSAFESWNAHQPKLLERKDTAGTVPESKAPKHYGDTTLLR 313
V GE GR + +S S + K + G S +P T R
Sbjct: 509 RSHVKNGEVGRRR------RHSPSRSASPSPRKRQKETSPRGRRRRSPSPP---PTRRRR 559
Query: 314 EPCPP-----ERTVSPCQVQASCSQEENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPSS 368
P P RT +P + + S R + S P R + +P
Sbjct: 560 SPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPP 619
Query: 369 QPDSQEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALD 428
P + P+ PP R+ K+ T +R P L +KH S +
Sbjct: 620 PPKRRASPSPPPKRRVSHSPPPKQ------RSSPVTKRRSPSLSSKHRKGSSPSRSTREA 673
Query: 429 LPVEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAER---TPSPPGQLNGYQEKEPSE 485
+PN+ + P P A ++ S P R + SP + Q PS
Sbjct: 674 RSPQPNKRHSPS-----------PRPRAPQTSSSPPPVRRGASSSPQRR----QSPSPST 718
Query: 486 CQSRDSYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILP 545
R ++ P K++K S SP V + V G EP +
Sbjct: 719 RPIRRVSRTPEP----------KKIKKAASPSP-QSVRRVSSSRSVSGSPEPAAK----- 762
Query: 546 NGLEESPPNELSKERPADD-PTASHINPQKDPTADPSEP 583
+PP+ + + P+ + A + K PT PS P
Sbjct: 763 --KPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPP 799
Score = 42.7 bits (99), Expect = 0.002
Identities = 74/315 (23%), Positives = 113/315 (35%), Gaps = 66/315 (20%)
Query: 116 SPPPTPVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTESQRCESRP-----TASKPPAL 170
SP P P +RR P R+ + P + S + + +R P TAS PP
Sbjct: 562 SPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPP 621
Query: 171 KNPPKFAPLPENSVNFC----FDSAFLTVRRVPAEVSNTHQNSYQPGRKHGEQES----- 221
K +P P+ V+ S+ +T RR P+ +S+ H+ P R E S
Sbjct: 622 KRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPS-LSSKHRKGSSPSRSTREARSPQPNK 680
Query: 222 --SKNPEMACHGSSSFLPAANDTATLCESK--FPSPHHKPV-----TGEPGRGKGTFLHS 272
S +P +SS P A+ + PSP +P+ T EP + K S
Sbjct: 681 RHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPS 740
Query: 273 ENSAFESWNAHQPKLLERKDTAGTVPESKAPKHYGDTTLLREPCPPERTVSPCQVQASCS 332
P+ + R ++ +V S P + P PP SP Q Q
Sbjct: 741 ------------PQSVRRVSSSRSVSGSPEP------AAKKPPAPP----SPVQSQ---- 774
Query: 333 QEENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPSSQPDSQEKPAQPPWRKPKTGKKGKE 392
S S W P + K+P+ P Q K K KK K+
Sbjct: 775 -----------SPSTNWSPAVP-----VKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKK 818
Query: 393 SLQDTLEEKTQTNQR 407
+D +K + +++
Sbjct: 819 HKKDKKHKKHKKHKK 833
Score = 34.3 bits (77), Expect = 0.89
Identities = 49/218 (22%), Positives = 88/218 (40%), Gaps = 29/218 (13%)
Query: 1007 PEGDIEDQPPPWQPEN-CWEEQTPGFKSHFL---STPRAGPPGRRLVPSERAN-SPNPGS 1061
P+ + PPP Q + + ++P S S R+ R P++R + SP P +
Sbjct: 631 PKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRA 690
Query: 1062 PGESSACSP----AASNIWEESSQAPGGPELL----PEEPNQASPWASSSPARVTRREDL 1113
P SS+ P A+S+ S +P + EP + AS SP V R +
Sbjct: 691 PQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR---V 747
Query: 1114 THALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELPAQLERTASKPPAV 1173
+ + G +P + P V + T+ +P + ++ + P+
Sbjct: 748 SSSRSVSGSPEPAAK---------KPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPS- 797
Query: 1174 PPKT---EKALRRAKKLASKRRKTDQAQEKHGESQEGK 1208
PP+ E ++ KK K+ K D+ +KH + ++ K
Sbjct: 798 PPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEK 835
Score = 31.2 bits (69), Expect = 7.5
Identities = 88/429 (20%), Positives = 155/429 (36%), Gaps = 67/429 (15%)
Query: 368 SQPDSQEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNAL 427
S + +E+ P RK ++ + S E+ +++ R P TK E
Sbjct: 161 SSREKRERSRSPRRRKSRSPSPRRRS-SPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEK 219
Query: 428 --DLPVEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSE 485
+LP + +P + + I+ + + P + PSP +EKE +
Sbjct: 220 TPELPEPSVKVKEPSVQEATSTSDILK----VPKPEPIPEPKEPSPEKNSKKEKEKEKTR 275
Query: 486 CQSRDSYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILP 545
+SR KS++ R R +S + P + + P P
Sbjct: 276 PRSRSRSKSRS----------RTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRR----P 321
Query: 546 NGLEESPPNELSKERPADDPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAKAPFYVN 605
+ +PP + P + S + ++ +A S S+ S + S +P K P
Sbjct: 322 SPRRRTPPRRMPPP-PRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSP--PKKP---- 374
Query: 606 GEAAERSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPGGATEKMKT 665
+R+S ++ + P+ S P R HRP + P T T
Sbjct: 375 ---PKRTSSPPRKTR---RLSPSAS---PPRRRHRP---------SPPATPPPKTRHSPT 416
Query: 666 HQLENGLSRSVSQETEPEREAGLQNTH--LNQKFFPGPLSPEEEDVFYSDSQSD------ 717
Q N +R P R +G H ++ P P +P+ V S+S+ D
Sbjct: 417 PQQSN-RTRKSRVSVSPGRTSGKVTKHKGTEKRESPSP-APKPRKVELSESEEDKGGKMA 474
Query: 718 FMPSLKGKAKF------STSSSDQSFASFDDQQKMWFTENQREDRRKDVSAGDS-----Q 766
S++ + ++ S+S S S +S D++ K +N RR+ S S +
Sbjct: 475 AADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPR 534
Query: 767 KDEKENVMR 775
K +KE R
Sbjct: 535 KRQKETSPR 543
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 53.1 bits (126), Expect = 2e-06
Identities = 111/490 (22%), Positives = 166/490 (33%), Gaps = 80/490 (16%)
Query: 884 SLSSGHKEEELPRPEWGEDPGFCAPENQDILGTSTPTNTR-----GTRVKCMANEVMEDP 938
S S +EEE E + A N +LG P++ + T M P
Sbjct: 83 STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP 142
Query: 939 GQGSSMARMEASQPAPKGNFPS--MPLVGEGDRVKAPP----DAAPGLV-ASNCKSGSAD 991
G ++A + + + K PS LV E + + P A PG+V A S S D
Sbjct: 143 ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSED 202
Query: 992 SGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFKSHFLS------TPR----A 1041
+ + + EG +P + + +++P K+ TP+ A
Sbjct: 203 TSSSSDETDV------EGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGA 256
Query: 1042 GPPGRRL-VPSERANSPNPGSPGESSACSPAASNI-------WEESSQAPG----GPELL 1089
PP +R P E + S GS E A + S + ++ AP G
Sbjct: 257 LPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGAT 316
Query: 1090 PEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATS 1149
P P +A AS + A + E S+ E S + T + + L A+
Sbjct: 317 PAPPGKAGAVASQTKAGKPEEDS-------ESSSE---ESSDSEEETPAAKALLQAKASG 366
Query: 1150 PAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKP 1209
G PA+ PA P KT A+ AK A KR + Q+ + +S+E P
Sbjct: 367 KTSQVGAASAPAKESPRKGAAPAPPGKTGPAV--AKAQAGKREEDSQSSSEESDSEEEAP 424
Query: 1210 CPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPA 1269
+ +P P VR+ P S G P P+ P A
Sbjct: 425 A--------------QAKPSGKAPQVRAASAPAKE------SPRKGAAPAPPRKTGPAAA 464
Query: 1270 YPATQKVLQDPQ-SGEYFVFDLPLQVKIKTFYDPETGKYVKVSI-------PSSEGASPE 1321
K +D + S E D + GK +V P +GA P
Sbjct: 465 QVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPV 524
Query: 1322 PPPPDALAAP 1331
PP A P
Sbjct: 525 PPGKVGPATP 534
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 53.1 bits (126), Expect = 2e-06
Identities = 111/490 (22%), Positives = 166/490 (33%), Gaps = 80/490 (16%)
Query: 884 SLSSGHKEEELPRPEWGEDPGFCAPENQDILGTSTPTNTR-----GTRVKCMANEVMEDP 938
S S +EEE E + A N +LG P++ + T M P
Sbjct: 83 STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP 142
Query: 939 GQGSSMARMEASQPAPKGNFPS--MPLVGEGDRVKAPP----DAAPGLV-ASNCKSGSAD 991
G ++A + + + K PS LV E + + P A PG+V A S S D
Sbjct: 143 ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSED 202
Query: 992 SGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFKSHFLS------TPR----A 1041
+ + + EG +P + + +++P K+ TP+ A
Sbjct: 203 TSSSSDETDV------EGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGA 256
Query: 1042 GPPGRRL-VPSERANSPNPGSPGESSACSPAASNI-------WEESSQAPG----GPELL 1089
PP +R P E + S GS E A + S + ++ AP G
Sbjct: 257 LPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGAT 316
Query: 1090 PEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATS 1149
P P +A AS + A + E S+ E S + T + + L A+
Sbjct: 317 PAPPGKAGAVASQTKAGKPEEDS-------ESSSE---ESSDSEEETPAAKALLQAKASG 366
Query: 1150 PAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKP 1209
G PA+ PA P KT A+ AK A KR + Q+ + +S+E P
Sbjct: 367 KTSQVGAASAPAKESPRKGAAPAPPGKTGPAV--AKAQAGKREEDSQSSSEESDSEEEAP 424
Query: 1210 CPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPA 1269
+ +P P VR+ P S G P P+ P A
Sbjct: 425 A--------------QAKPSGKAPQVRAASAPAKE------SPRKGAAPAPPRKTGPAAA 464
Query: 1270 YPATQKVLQDPQ-SGEYFVFDLPLQVKIKTFYDPETGKYVKVSI-------PSSEGASPE 1321
K +D + S E D + GK +V P +GA P
Sbjct: 465 QVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPV 524
Query: 1322 PPPPDALAAP 1331
PP A P
Sbjct: 525 PPGKVGPATP 534
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 53.1 bits (126), Expect = 2e-06
Identities = 111/490 (22%), Positives = 166/490 (33%), Gaps = 80/490 (16%)
Query: 884 SLSSGHKEEELPRPEWGEDPGFCAPENQDILGTSTPTNTR-----GTRVKCMANEVMEDP 938
S S +EEE E + A N +LG P++ + T M P
Sbjct: 83 STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP 142
Query: 939 GQGSSMARMEASQPAPKGNFPS--MPLVGEGDRVKAPP----DAAPGLV-ASNCKSGSAD 991
G ++A + + + K PS LV E + + P A PG+V A S S D
Sbjct: 143 ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSED 202
Query: 992 SGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFKSHFLS------TPR----A 1041
+ + + EG +P + + +++P K+ TP+ A
Sbjct: 203 TSSSSDETDV------EGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGA 256
Query: 1042 GPPGRRL-VPSERANSPNPGSPGESSACSPAASNI-------WEESSQAPG----GPELL 1089
PP +R P E + S GS E A + S + ++ AP G
Sbjct: 257 LPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGAT 316
Query: 1090 PEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATS 1149
P P +A AS + A + E S+ E S + T + + L A+
Sbjct: 317 PAPPGKAGAVASQTKAGKPEEDS-------ESSSE---ESSDSEEETPAAKALLQAKASG 366
Query: 1150 PAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKP 1209
G PA+ PA P KT A+ AK A KR + Q+ + +S+E P
Sbjct: 367 KTSQVGAASAPAKESPRKGAAPAPPGKTGPAV--AKAQAGKREEDSQSSSEESDSEEEAP 424
Query: 1210 CPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPA 1269
+ +P P VR+ P S G P P+ P A
Sbjct: 425 A--------------QAKPSGKAPQVRAASAPAKE------SPRKGAAPAPPRKTGPAAA 464
Query: 1270 YPATQKVLQDPQ-SGEYFVFDLPLQVKIKTFYDPETGKYVKVSI-------PSSEGASPE 1321
K +D + S E D + GK +V P +GA P
Sbjct: 465 QVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPV 524
Query: 1322 PPPPDALAAP 1331
PP A P
Sbjct: 525 PPGKVGPATP 534
>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c [Homo
sapiens]
Length = 958
Score = 53.1 bits (126), Expect = 2e-06
Identities = 111/490 (22%), Positives = 166/490 (33%), Gaps = 80/490 (16%)
Query: 884 SLSSGHKEEELPRPEWGEDPGFCAPENQDILGTSTPTNTR-----GTRVKCMANEVMEDP 938
S S +EEE E + A N +LG P++ + T M P
Sbjct: 83 STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHP 142
Query: 939 GQGSSMARMEASQPAPKGNFPS--MPLVGEGDRVKAPP----DAAPGLV-ASNCKSGSAD 991
G ++A + + + K PS LV E + + P A PG+V A S S D
Sbjct: 143 ATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSED 202
Query: 992 SGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFKSHFLS------TPR----A 1041
+ + + EG +P + + +++P K+ TP+ A
Sbjct: 203 TSSSSDETDV------EGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGA 256
Query: 1042 GPPGRRL-VPSERANSPNPGSPGESSACSPAASNI-------WEESSQAPG----GPELL 1089
PP +R P E + S GS E A + S + ++ AP G
Sbjct: 257 LPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGAT 316
Query: 1090 PEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATS 1149
P P +A AS + A + E S+ E S + T + + L A+
Sbjct: 317 PAPPGKAGAVASQTKAGKPEEDS-------ESSSE---ESSDSEEETPAAKALLQAKASG 366
Query: 1150 PAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKP 1209
G PA+ PA P KT A+ AK A KR + Q+ + +S+E P
Sbjct: 367 KTSQVGAASAPAKESPRKGAAPAPPGKTGPAV--AKAQAGKREEDSQSSSEESDSEEEAP 424
Query: 1210 CPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPA 1269
+ +P P VR+ P S G P P+ P A
Sbjct: 425 A--------------QAKPSGKAPQVRAASAPAKE------SPRKGAAPAPPRKTGPAAA 464
Query: 1270 YPATQKVLQDPQ-SGEYFVFDLPLQVKIKTFYDPETGKYVKVSI-------PSSEGASPE 1321
K +D + S E D + GK +V P +GA P
Sbjct: 465 QVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPV 524
Query: 1322 PPPPDALAAP 1331
PP A P
Sbjct: 525 PPGKVGPATP 534
>gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo
sapiens]
Length = 1393
Score = 52.8 bits (125), Expect = 2e-06
Identities = 247/1249 (19%), Positives = 404/1249 (32%), Gaps = 238/1249 (19%)
Query: 137 NKPVSKVSTLIKSFDRTESQRCESRPTASKPPALKNPPKFAPLPENSVNFCFDSAFLTVR 196
+KP K + K+ D S P S+ ENS N D R
Sbjct: 93 SKPTDKPTGNSKTIDHKSSTDNHEAPPTSE--------------ENSSNQGKDPMIRNQR 138
Query: 197 RV-PAEVSNTHQNSYQPGRKH--GEQESSKNPEMACHGSSSFLPAANDTATLCES----- 248
V PA+ + TH+ S G+KH +S N + G S+ ++ T E
Sbjct: 139 SVDPADSTTTHKES--AGKKHITPAPKSKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTL 196
Query: 249 -KFPSPHHKPVTGEPGRGKGTFLHSENSAFESWNAHQPKLLERKDTAGTVPESKAPKHYG 307
K + HK T G S E A + T GT PE
Sbjct: 197 DKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYK---TTGT-PEESEKTEDS 252
Query: 308 DTTLLREPCPPERTVSPCQVQASCSQEENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPS 367
TT+ + + T + ++A L+ S+ G A E PS
Sbjct: 253 RTTVASDKLLTKTT----------KNIQETISANELTQSLAEPTEHGGRT--ANENNTPS 300
Query: 368 SQPDSQEKPAQPPWRKPKTGKKGK--------ESLQDTLEEKTQTNQRGPPLYTKHNPQE 419
PA+P + +T + E+ + T E T GP N +
Sbjct: 301 --------PAEPTENRERTANENTTLSPAEPIENRERTANENTAPFPAGPT----ENREM 348
Query: 420 QFSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKH----ALDSADSQPAE--------- 466
+EN L P EP EH + N + +P P++H A ++ PAE
Sbjct: 349 TANENTTL-FPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTP 407
Query: 467 ----RTPSPPGQLNGYQEK-------------EPSECQSRDSYKSKAPSLLFNLKDVRKR 509
+T S + + E+ EP+E + R + ++ PS ++
Sbjct: 408 FANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETT 467
Query: 510 VKSTYSSSPLLKVLDEKTRGK---VDGKQEPVSNGVILPNGLEESP-------------- 552
+ SP+ + +T EP NG P E++
Sbjct: 468 ANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTP 527
Query: 553 -PNELSKERPADDPTASHINPQKDPTADPSEPSADSYLT----LSTAPTIAKAPFYVNGE 607
NE + PA+ + T P+EP+ + T T P++A+ E
Sbjct: 528 LANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPT-----E 582
Query: 608 AAERSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPGGATEKMKTHQ 667
+R+ + N++ +S + EH R L+ N P P TE +
Sbjct: 583 NGQRTPFANEKT----------TSSSAEPTEHEERTPLANE--NTTPSPAEPTENRE--- 627
Query: 668 LENGLSRSVSQETEPEREAGLQNTHL--NQK--FFPG-PLSPEEEDVFYSDSQSDFMPSL 722
R+ ++ T P +N + N+K FP P E + S P+
Sbjct: 628 ------RTANENTTPSPAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTE 681
Query: 723 KGK----AKFSTSSSDQSFASFDDQQKMWFTENQREDRRKDVSAGDSQKDEKENVMRKDE 778
G+ A T+SS ++ + EN + + +EK +
Sbjct: 682 NGQRTPFANEKTTSSSAEPTEHGERTPL-ANENTTLSPAEPTENRERTANEKTTPFPAEP 740
Query: 779 LQYCALSNGHACLENRSQGEALQRERESVSGGRTRKASAEEANFRGSWIGENKGTTFSQA 838
+ + EN + A E +G RT A+ + K T F+
Sbjct: 741 TE----NRERTANENTTPSPAQPTE----NGDRTPLANEKTTPSLAEPTENGKRTPFANE 792
Query: 839 KDLTPSPSSASNRHMLFTIKDNTLRA----------TPVIKPIMLPLLRTMSLEDSLSSG 888
K + S + +NT + T K P T + E + +
Sbjct: 793 KTTSSSAEPTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTAN-- 850
Query: 889 HKEEELPRP-EWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVM----EDPGQGSS 943
E+ P P E E+ + A EN + S T + +ANE +P +
Sbjct: 851 --EKTTPFPAEPTENREWTANENTTL---SPAEPTEHEEMTPLANEKTTLSPAEPTENGE 905
Query: 944 MARMEASQPAPKGNFPSMPLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIPT 1003
+ P P+ G+R + A + G + + A P
Sbjct: 906 RTPFTNEKTTPSSAEPT----EHGERTPLANEITTPSRAEPTEHGERIANEKATPSPAKP 961
Query: 1004 IALPEGDIEDQPPPWQPENCWE-EQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSP 1062
E + + P E E+TP + ++P +E+ +P+P P
Sbjct: 962 TEHGETTVNEDTTPSSAEPTENGERTPLANENTTTSPTESTEHGERTANEK-TTPSPAEP 1020
Query: 1063 GESSACSPAASNIWEESSQAPGGPELLPEEPNQASPWASSSPARVTRREDLTH------A 1116
E +P+A+ E++ +P P E A+ + SP + T + T
Sbjct: 1021 TEHGERTPSAN---EKTIPSPAKPTEHEEMTPSANENTTPSPVKPTEHGEKTTLANEKIT 1077
Query: 1117 LVWEGGSD--------------PLLELSAEDLRTLSPRGSLLDVATSPA-----GTSGRL 1157
L EG ++ L + + RT SP + A TS +
Sbjct: 1078 LSPEGPTEHGAKTTSANEKITPSLAKPTEHGERTTSPNDKITSSAAESTEHRDRATSANV 1137
Query: 1158 ELPAQLE------RTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEK---HGES---Q 1205
PA E RT + TEK+ +K S KT + EK + E
Sbjct: 1138 ITPAPAEPIKHAKRTTLAHEKMTQVTEKSTEHPEKTTSTTEKTTRTPEKPTLYSEKTICT 1197
Query: 1206 EGK--PCPED----------LEQTQQRPLCPRERPRHNFPVVRSLPPPV 1242
+GK P PE +T + P+ E P V +++ P V
Sbjct: 1198 KGKNTPVPEKPTENLGNTTLTTETIKAPVKSTENPEKTAAVTKTIKPSV 1246
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 51.2 bits (121), Expect = 7e-06
Identities = 135/591 (22%), Positives = 198/591 (33%), Gaps = 88/591 (14%)
Query: 810 GRTRKASAEEANFRGSWIGENKGTTFSQAKDLTPSPSSASNRHMLFTIKDNTLRATPVIK 869
G TR A N +G AK+ +P P S+ R T R P+ +
Sbjct: 78 GPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGR------ASGTTRPGPLGQ 131
Query: 870 PIMLPLLRTMSLEDSLSSGHKEEELPRPEWGEDPGFCAPENQDILGTS--TPTNTRGTRV 927
+ +S E++++ G K E P+ A +D G + TP+ R
Sbjct: 132 KGL-----RISAEETVARG-KATEAPKRS-----ALSAGARRDTSGPTPGTPSPAMARRS 180
Query: 928 KCMANEV----------MEDPGQG-----SSMARMEASQPAPKGNFPSMPLVGEGDRVKA 972
+ EV P +G SS + ++P+P P G G + A
Sbjct: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAAR--RRPSAGGGLQRPA 238
Query: 973 PPDAAPGL--VASNCKSGSADSGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPG 1030
+ ++S +SG + G AP H P+ P+G +PP P ++ P
Sbjct: 239 SRSLSSSATPLSSPARSGPSARGTPRAPAH-PSQPKPKGLQALRPPQVTPPR--KDAAPA 295
Query: 1031 FKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNI--WEESSQAPGGPEL 1088
S+P A P + S+ A P +P SS A+ + S AP +
Sbjct: 296 L-GPLSSSPLATPSPSAALQSQ-APPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQT 353
Query: 1089 LPEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVAT 1148
LP P A+P + ++ + + TH+ + P L +AT
Sbjct: 354 LPSPP--ATPPSQATTSLGSPTLQATHSFL--------------------PSPPLSPLAT 391
Query: 1149 SPAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGK 1208
P L LP + PPA PP + LA+ + A H
Sbjct: 392 PPPQAPPALALPPL--QAPPSPPASPPLSP--------LATPSPQAPNALAVHLLQAPFS 441
Query: 1209 PCPEDLEQTQ-----QRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQS 1263
P P Q P+ P P P + PP S S P+ P
Sbjct: 442 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA-SPPMSPSATPPPQ 500
Query: 1264 LTPLPAYPATQKVLQDPQSGEYFVFDLPLQV--KIKTFYDPETGKYVKVSIPSSEGASPE 1321
P A P Q PQ+ PLQ + + S+P S A+P
Sbjct: 501 APPPLAAPPLQLAKPPPQAPPALATP-PLQALPSPPASFPGQAPFSPSASLPMSPLATPP 559
Query: 1322 PPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASAARA 1372
P P LAAP + P P T P R P GPR + A A
Sbjct: 560 PQAPPVLAAPLLQVPPSPPASPTLQAPRR--PPTPGPDTSVSGPRLTLALA 608
>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis
critical region 1 [Homo sapiens]
Length = 1400
Score = 50.4 bits (119), Expect = 1e-05
Identities = 128/593 (21%), Positives = 202/593 (34%), Gaps = 126/593 (21%)
Query: 137 NKPVSKVSTLIKSFDRTESQRCESRPTASKPPALKNPPKFAPLPENSVNFCFDSAFLTVR 196
+KP K + K+ D S P S+ ENS N D R
Sbjct: 155 SKPTDKPTGNSKTIDHKSSTDNHEAPPTSE--------------ENSSNQGKDPMIRNQR 200
Query: 197 RV-PAEVSNTHQNSYQPGRKH--GEQESSKNPEMACHGSSSFLPAANDTATLCES----- 248
V PA+ + TH+ S G+KH +S N + G S+ ++ T E
Sbjct: 201 SVDPADSTTTHKES--AGKKHITPAPKSKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTL 258
Query: 249 -KFPSPHHKPVTGEPGRGKGTFLHSENSAFESWNAHQPKLLERKDTAGTVPESKAPKHY- 306
K + HK T G S E A + T GT ES+ +
Sbjct: 259 DKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYK---TTGTPEESEKTEDSR 315
Query: 307 ----GDTTLLREPCPPERTVSPCQVQASCSQEENRLAAGALSTSIPWGCRDPGAQVFAVE 362
D L + + T+S ++ S ++ A + P + E
Sbjct: 316 TTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRTANENNTP-------SPAEPTE 368
Query: 363 GKAPSSQPDSQEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQFS 422
+ ++ ++ PA+P E+ + T E T GP N + +
Sbjct: 369 NRERTANENTTLSPAEPT-----------ENRERTANENTAPFPAGPT----ENREMTAN 413
Query: 423 ENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKE 482
EN L P EP EH + N + +P P++H +A+ TPSP E
Sbjct: 414 ENTTL-FPAEPTEHGERTANENTTPSPAEPTEHGERTANE---NTTPSP---------AE 460
Query: 483 PSECQSRDSYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGV 542
P+E R + + K+T SS+ E T G++ P++N
Sbjct: 461 PTEHGERTPFAND---------------KTTSSSA-------ESTE---HGERTPLANEN 495
Query: 543 ILPNGLE-----ESPPNELSKERPADDPTASHINPQKDPTADPSEPSADSYLTLSTAPTI 597
P+ E E NE + PA + T P EP+ + T + T
Sbjct: 496 TTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTP 555
Query: 598 AKAPFYVNGEAAERSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPG 657
+ A NG +R+ + N++ +S + EH R L+ N P P
Sbjct: 556 SPAEPTENG---QRTPFANEKT----------TSSSAEPTEHGERTPLANE--NTTPSPA 600
Query: 658 GATEKMKTHQLENGLSRSVSQETEPE----REAGLQNTHLNQKFFPGPLSPEE 706
TE + R+ +++T P E G + N+K P P E
Sbjct: 601 EPTENRE---------RTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTE 644
Score = 45.1 bits (105), Expect = 5e-04
Identities = 94/437 (21%), Positives = 147/437 (33%), Gaps = 54/437 (12%)
Query: 196 RRVPAEVSNTHQNSYQPGRKHGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHH 255
+R P T +S +P +HGE+ N S P N T E PSP
Sbjct: 565 QRTPFANEKTTSSSAEP-TEHGERTPLANENTT---PSPAEPTENRERTANEKTTPSPAE 620
Query: 256 KPVTGE--PGRGKGTFLHSENSAFESWNAHQPKLLERKDTAG----TVPESKAPKHYGDT 309
G+ P + T + + A + N + K T+ T E + P +T
Sbjct: 621 PTENGDRTPLANEKT---TPSLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENT 677
Query: 310 TLLREPCPP----ERTVSPCQVQASCSQEENR-LAAGALSTSIPWGCRDPGAQVFAVEGK 364
T P P ERT + + ENR + A +T P + K
Sbjct: 678 T--PSPAEPTENRERTANENTTPSPAGPTENREMTANEKTTLFP--AEPTENRERTANEK 733
Query: 365 APSSQPDSQEKPAQPPWRKPKTGKKGKESLQD-----TLEEKTQTNQRGPPLYTKHNPQE 419
SS + E + P+ KT E + E T + GP +E
Sbjct: 734 TTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAGPT-----ENRE 788
Query: 420 QFSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHA----LDSADSQPAERTPSPPGQL 475
+ + P EP E+ + N + +P P+++ L + + P+ P+ G+
Sbjct: 789 RTANEKTTPFPAEPTENRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENGKR 848
Query: 476 NGY-QEKEPSECQSRDSYKSKAPSLLFNLKDVRKRVKSTYSSSPLLKVLDEKTRGKVDGK 534
+ EK S + + P N +SSP E T +
Sbjct: 849 TPFANEKTTSSSAEPTEHAERTPLANENT-----------TSSPA-----EPTENRERTA 892
Query: 535 QEPVSNGVILPNGLEESPPNELSKERPADDPTASHINPQKDPTADPSEPSADSYLTLSTA 594
E + P ES NE + PA+ ++ T P+EP+ +T
Sbjct: 893 NEKTTQFPAEPTENRESTANEKTTPFPAEPTENREWTANENTTLSPAEPTEHEEMTPLMV 952
Query: 595 PTIAKAPFYVNGEAAER 611
+APF G AER
Sbjct: 953 DENLQAPFR-QGSCAER 968
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 50.4 bits (119), Expect = 1e-05
Identities = 247/1175 (21%), Positives = 399/1175 (33%), Gaps = 201/1175 (17%)
Query: 219 QESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENSAFE 278
++ SK P H SSS P + SP + P R S FE
Sbjct: 824 KQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQR---------RSCFE 874
Query: 279 SWNAHQPKLLERKDTAGTVPESKAPKHYGDTTLLREPCPPERTVSPCQVQASCSQEENRL 338
S + P+L R + + S P+ T + P R+ SP + R
Sbjct: 875 S--SPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSP---SRSSSPQPKVKAIISPRQRS 929
Query: 339 AAGALSTSIPW--------------GCRDPGAQVFAVEGKAPSSQPDSQEKPAQPPWRKP 384
+G+ S S C + +++ + SS PD++ KP PP R+
Sbjct: 930 HSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPP-RQS 988
Query: 385 KTGKKGKESLQDTLEEKTQTNQRGPPLYTKHN--PQEQFSENNALDLP------------ 430
+G S+ + K QT GP L + PQE+ ++ P
Sbjct: 989 HSG-----SISPYPKVKAQT-PPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSS 1042
Query: 431 VEPNEHYDPPFNISKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPS-ECQSR 489
P E Y F +S L + + P R+ + ++ + PS + +S+
Sbjct: 1043 TPPGESY---FGVSSL--------QLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQ 1091
Query: 490 DSYK-----SKAPSLLFNLKDVRKRVKSTYSSSPLLK--VLDEKTRGKVDGKQEPV--SN 540
S K S +P + ++ + +S+SP+LK + E++R + D P SN
Sbjct: 1092 TSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSN 1151
Query: 541 GVILPNGLEESPPNELSKERPADDPTASHINPQKD-----PTADPSEPSADSYLTLSTAP 595
++ + LE + E P +D TAS QKD P D E S TL T P
Sbjct: 1152 SLLGQSRLETAESKEKMALPPQEDATASPPR-QKDKFSPFPVQDRPESSLVFKDTLRTPP 1210
Query: 596 T----IAKAPFYVNGEAAERSSYENKEVEGELEMG--PAG--------------SSWCPD 635
+P +A +S +++E+ +E PAG +S
Sbjct: 1211 RERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFES 1270
Query: 636 SREHRPRKHLSLRLCNRDPEPGGATEKMKTHQLENGLSRSVSQETEPEREAGLQNTHLNQ 695
S E R +SL L + + ++ ++ + S PE + L N+ L +
Sbjct: 1271 SPEVEERPAVSLTL-----DQSQSQASLEAVEVPSMASSWGGPHFSPEHKE-LSNSPLRE 1324
Query: 696 KFF--------PGPLSPEEEDVFYSDSQSDFM----------PSLKGKAKFSTSSS-DQS 736
F GPL E F S+ + D PSL K + + SS S
Sbjct: 1325 NSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSS 1384
Query: 737 FASFDDQQKMWFTENQR----------EDRRKDVSAGDSQKDEKENVMRKDELQYCALSN 786
S D +K + NQ ++ S+ S + K+ + R + + S
Sbjct: 1385 ELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRR--SRSG 1442
Query: 787 GHACLENRSQGEALQRERESVSGGRTRKASAEEANFRGSWIGENKGTTFSQAKDLTPSPS 846
L + S + R S+SG RG E + +A TP P
Sbjct: 1443 SSPGLRDGSGTPS----RHSLSGSSPGMKDIPRTPSRGR--SECDSSPEPKALPQTPRPR 1496
Query: 847 SAS------NRHMLFTIKDNTLRATPVIKPIMLPLLRTMSLEDSLSSGHKEEELPRPEWG 900
S S N L ++ + + V + + RT + S S +E ++
Sbjct: 1497 SRSPSSPELNNKCLTPQRERSGSESSVDQK---TVARTPLGQRSRSGSSQELDVKPSASP 1553
Query: 901 EDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAPKGNFPS 960
++ T TP R + ++ ++ + S S P K +
Sbjct: 1554 QERSESDSSPDSKAKTRTPLRQRS---RSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRA 1610
Query: 961 MPLVGEG-DRVKAPPDAAPGLVASNCKSGSADSGK----------LAAPWHIP------- 1002
P G D P AP + +SGS+ G+ ++P H P
Sbjct: 1611 APRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARR 1670
Query: 1003 -TIALPEGDIEDQPPPWQ------PENCWEEQTPGFKSHFLSTPRA---GPPGRRLVPSE 1052
+ + PE + + PP + PE + + S+P PP R PS
Sbjct: 1671 GSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPS- 1729
Query: 1053 RANSPNPGSPGESSACSPAASNIWEESSQAPG-GPELLPEEPNQASPWASSSPARVTRRE 1111
+SP P SS +AS+ +++ G P P ++ + R TRR
Sbjct: 1730 -VSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRR 1788
Query: 1112 DLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELPAQLERTASK-- 1169
D GS + R+ R + +G R + RT+S+
Sbjct: 1789 D-------RSGSSQSTSRRRQRSRS---RSRVTRRRRGGSGYHSRSPARQESSRTSSRRR 1838
Query: 1170 --PPAVPPKTEKALR-RAKKLASKRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRE 1226
PP + K R R KR ++ + H S+ P + R
Sbjct: 1839 RGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRR 1898
Query: 1227 RPRHNFPVV----RSLPPPVHRHSVSGFSEPVGRR 1257
R R V RS PV R + PV RR
Sbjct: 1899 RSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRR 1933
Score = 45.1 bits (105), Expect = 5e-04
Identities = 82/353 (23%), Positives = 126/353 (35%), Gaps = 50/353 (14%)
Query: 1040 RAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPGGPELLPEEPNQASPW 1099
R+ P RR S R+ S P G S + +PA + A P +
Sbjct: 636 RSRSPARR---SGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRS 692
Query: 1100 ASSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLEL 1159
S +P R R + +LV G S RT RG +G+S +
Sbjct: 693 RSRTPRRGRSR---SRSLVRRGRSHS---------RTPQRRGR--------SGSSSERKN 732
Query: 1160 PAQLERTASKPPAVPP--KTEKALRRAKKLASKRRKTDQAQEKHGESQEGKPCPEDLEQT 1217
++ + S+ + P K+ + RR++ L+S R K PCP+ QT
Sbjct: 733 KSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQT 792
Query: 1218 QQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGP-----QSLTPLP---- 1268
R R R + P +S PP R S S S P ++ P S +P P
Sbjct: 793 PPR----RSRSGSSQPKAKSRTPP--RRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKS 846
Query: 1269 AYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPSSEGASPEPPPPDAL 1328
P Q + PQ+ E V + ++ ++ +K PS S PP
Sbjct: 847 GTPPRQGSITSPQANEQSV-----TPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKS 901
Query: 1329 AAPYVLYPGFQPVPVTALMPL-----RCSSQLSAPTFLRQGPRASAARARTQS 1376
+ P P P + + R S S+P+ R R + R+R+ S
Sbjct: 902 STPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVS 954
Score = 34.7 bits (78), Expect = 0.68
Identities = 56/245 (22%), Positives = 84/245 (34%), Gaps = 45/245 (18%)
Query: 1177 TEKALRRAKKLASKRRKTD----QAQEKHGESQEGKPCPEDLEQTQQRPLCPRERPRHNF 1232
T K+ R++K KR ++ +++ H + D +++ R + H
Sbjct: 233 TPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKT---HTT 289
Query: 1233 PVVRSLPPPVHRHSVSG---FSEP---VGRRPGGPQSLTPLPAYPATQKVLQDPQSGEYF 1286
+ P P G FSEP +RP P++ T P+ P K
Sbjct: 290 ALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDK----------- 338
Query: 1287 VFDLPLQVKIKTFYDPETGKYVKVSIPSSEGASPEPPPPDALAAPYVLYPGF-QPVPVTA 1345
D + K T P P PEPP P L A + G QP+ T
Sbjct: 339 --DKDKKEKSATRPSPS---------PERSSTGPEPPAPTPLLAE--RHGGSPQPLATTP 385
Query: 1346 LM--PLRCSSQLSAPTFLRQGPRASAARARTQSVHESGLQLDPGPHGDCTPHSAGQRPHG 1403
L P+ S+ S PT R P++ ++ S S P P A P
Sbjct: 386 LSQEPVNPPSEAS-PTRDRSPPKSPEKLPQSSSSESS----PPSPQPTKVSRHASSSPES 440
Query: 1404 PPQSP 1408
P +P
Sbjct: 441 PKPAP 445
Score = 34.3 bits (77), Expect = 0.89
Identities = 191/1020 (18%), Positives = 331/1020 (32%), Gaps = 140/1020 (13%)
Query: 313 REPCPPER-TVSPCQVQASCSQEEN---RLAAGALSTSIPWGCRDPGAQVFAVEGKAPSS 368
+E P +R V+ A ++++N R A G + + DP Q A E K P+
Sbjct: 108 KEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDP--QRRAREAKQPAP 165
Query: 369 QPDS------QEKPAQPPWRKPKTGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQ-EQF 421
+P + ++ P K K KK K+ + + + ++ KH + E
Sbjct: 166 EPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESK 225
Query: 422 SENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHA-----LDSADSQP------------ 464
+ P + D S+ TP S+ A DSA S
Sbjct: 226 KRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAK 285
Query: 465 ------AERTPSPPGQLNGYQEKEPSECQSRDSYK-------SKAPSLLFNLKDVRKRVK 511
A R+PSP G + SE + + + +K PS + KD K+ K
Sbjct: 286 THTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEK 345
Query: 512 STYSSSPLLK-------------VLDEKTRGKVDG------KQEPVSNGVILPNGLEESP 552
S SP + +L E+ G QEPV+ + SP
Sbjct: 346 SATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSP 405
Query: 553 PNELSK---------ERPADDPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAKAPFY 603
P K P+ PT + P + P+ S+ +S++PT
Sbjct: 406 PKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRS-- 463
Query: 604 VNGEAAERSSYENKEVEGELEMGPAGSSWCPDSREHRPRKHLSLRLCNRDPEPGGATEKM 663
+G A S+ + ++ SR P K R +R P+ +
Sbjct: 464 -HGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSR--SRSPQWRRSRSAQ 520
Query: 664 KTHQLENGLSRSVSQETEPEREAGLQNTHLNQKFFPGPLSPEEEDVFYSDSQS------D 717
+ + + R S+ P+R ++ + ++ G +S S +
Sbjct: 521 RWGRSRSPQRRGRSR--SPQRPGWSRSRNTQRR---GRSRSARRGRSHSRSPATRGRSRS 575
Query: 718 FMPSLKGKAKFSTSSSDQSFASFDDQQKMWFTENQREDRRKDVSAGDSQKDEKENVMRKD 777
P+ +G+++ T + +S + +++ R R + + + + V R+
Sbjct: 576 RTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRS 635
Query: 778 ELQYCALSNGHA-----CLENRSQGEALQRERESVS-----------------GGRTRKA 815
+ A +G + RS+ R S S GR+R
Sbjct: 636 RSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSR 695
Query: 816 SAEEANFRGSWIGENKGTTFSQAKDLTPSPSSASNRHMLFTIKDNTLR--ATPVIKPIML 873
+ R + +G + S+ S+S R R ++P +K +
Sbjct: 696 TPRRGRSRSRSL-VRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRI 754
Query: 874 PLLRTMSLEDSLSSGHKEEELPRPEWGEDPGFC------APENQDILGTSTP---TNTRG 924
R+ SL S L R G P C P + G+S P + T
Sbjct: 755 SSRRSRSLSSPRSKAKSRLSLRRSLSGSSP--CPKQKSQTPPRRSRSGSSQPKAKSRTPP 812
Query: 925 TRVKCMANEVMEDPGQGSSMARMEASQPAPKGNFPSMPLVGEGDRVKAPPDAAPGLVASN 984
R + ++ + + S +S P PK + P G +A + S
Sbjct: 813 RRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSC 872
Query: 985 CKSGSADSGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPP 1044
+S K P ++ PP Q + P K+ R+
Sbjct: 873 FESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSG 932
Query: 1045 GRRLVPSERANSPNPGSPGESSACSPAASNI---WEESSQAPGGPELLPEEPNQASPWAS 1101
PS + P S CS S + + S + ++ PE P + S S
Sbjct: 933 SSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGS 992
Query: 1102 SSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVA----TSPAGTS--- 1154
SP + + + G P + ++D S GSL A ++P G S
Sbjct: 993 ISPYPKVKAQTPPGPSL-SGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFG 1051
Query: 1155 -GRLELPAQLERTAS-KPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKPCPE 1212
L+L Q + + + P+ ++ + L SK Q K G S+ P E
Sbjct: 1052 VSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSK----SQTSPKGGRSRSSSPVTE 1107
Score = 34.3 bits (77), Expect = 0.89
Identities = 65/313 (20%), Positives = 109/313 (34%), Gaps = 47/313 (15%)
Query: 946 RMEASQPAPKGN----FPSMPLVGEGDRVKAPPDAAPGLVASNCKSGSADS------GKL 995
R ++ PAPK S D ++ +A + +G + S G+
Sbjct: 247 RSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEG 306
Query: 996 AAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERAN 1055
AP+ P + + QP + +E++ K + P P P A
Sbjct: 307 DAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAP 366
Query: 1056 SP-----NPGSPGESSACSPAASNIWEESSQA--------PGGPELLPEEPNQASPWASS 1102
+P + GSP + A +P + S+A P PE LP+ + S S
Sbjct: 367 TPLLAERHGGSP-QPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSP 425
Query: 1103 SPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELPAQ 1162
P +V+R HA S E + GS ++++SP + R A+
Sbjct: 426 QPTKVSR-----HA-----------SSSPESPKPAPAPGSHREISSSPT-SKNRSHGRAK 468
Query: 1163 LERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKPCPEDLEQTQQ--R 1220
+++ S P+ R+ A + R + K G S+ P Q+ R
Sbjct: 469 RDKSHSHTPS----RRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGR 524
Query: 1221 PLCPRERPRHNFP 1233
P+ R R P
Sbjct: 525 SRSPQRRGRSRSP 537
Score = 30.8 bits (68), Expect = 9.8
Identities = 44/217 (20%), Positives = 70/217 (32%), Gaps = 37/217 (17%)
Query: 894 LPRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPA 953
+P + GE P + L P R + SS + +S +
Sbjct: 2501 VPHSDVGEPPASTGAQQPSALAALQPAKERRSS---------SSSSSSSSSSSSSSSSSS 2551
Query: 954 PKGNFPSMPLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIPTIALPEGDIED 1013
+ S EG + P+ A V S PT A E E
Sbjct: 2552 SSSSSGSSSSDSEGSSLPVQPEVALKRVPS------------------PTPAPKEAVREG 2593
Query: 1014 QPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAAS 1073
+PP E TP + S+ + S ++S + S SS+ S ++S
Sbjct: 2594 RPP---------EPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2644
Query: 1074 NIWEESSQAPGGPELLPEEPNQASPWASSSPARVTRR 1110
+ S PG P+ LP+ + P +R R+
Sbjct: 2645 SSSSPSPAKPG-PQALPKPASPKKPPPGERRSRSPRK 2680
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 46.6 bits (109), Expect = 2e-04
Identities = 116/493 (23%), Positives = 152/493 (30%), Gaps = 48/493 (9%)
Query: 919 PTNTRGTRVKCMANEVMEDPGQGSSMARMEAS-QPAPKGN----FPSMPLVGEGDRVKAP 973
P + RG R N PG SS R + +P P G + V G +AP
Sbjct: 86 PASGRGERAPPAKNT---SPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAP 142
Query: 974 PDAAPGLVASNCKSGSADSGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFKS 1033
+A A SG A A E + P +P E S
Sbjct: 143 KRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSS 202
Query: 1034 HFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPGGPELLPEEP 1093
+ P R PS P S SS+ +P +S S + G P P
Sbjct: 203 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA--RSGPSARGTPRAPAHP 260
Query: 1094 NQASPWASSS--PARVTR-REDLTHAL--------VWEGGSDPLLELSAEDLRTL-SPRG 1141
+Q P + P +VT R+D AL S P + L+TL SP
Sbjct: 261 SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPA 320
Query: 1142 SLLDVATSPAGT---------------SGRLELPAQLERTASKPPAVPPKTEKALRRAKK 1186
+ AT+ G+ S P Q + PP P + A
Sbjct: 321 TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSP 380
Query: 1187 LASKRRKTDQAQEKHGESQEGKPCPEDLEQTQ-----QRPLCPRERPRHNFPVVRSLPPP 1241
LA+ + A H P P Q P+ P P P + PP
Sbjct: 381 LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL 440
Query: 1242 VHRHSVSGFSEPVGRRPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQV--KIKTF 1299
S S P+ P P A P Q PQ+ PLQ
Sbjct: 441 QVPPSPPA-SPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP-PLQALPSPPAS 498
Query: 1300 YDPETGKYVKVSIPSSEGASPEPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPT 1359
+ + S+P S A+P P P LAAP + P P T P R P
Sbjct: 499 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR--PPTPGPD 556
Query: 1360 FLRQGPRASAARA 1372
GPR + A A
Sbjct: 557 TSVSGPRLTLALA 569
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 46.2 bits (108), Expect = 2e-04
Identities = 96/360 (26%), Positives = 120/360 (33%), Gaps = 75/360 (20%)
Query: 1041 AGPPGRRLVPSERANSPNPGSPG-ESSACSPAA----SNIWEESSQ-------------- 1081
A PPG RLVP+ P P PG ES C PA S++ E Q
Sbjct: 322 AHPPGHRLVPAAPPG-PGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAATT 380
Query: 1082 --APGGPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGGSD----PLLELSAEDLR 1135
P P P P + +SSS + R + + G+D P LE+S
Sbjct: 381 ACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGI--PGADHYQTPALEVSHHGRL 438
Query: 1136 TLSPRGSLLDVATSPAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTD 1195
S S +PA T L LP S PP PP + LR A +
Sbjct: 439 GPSAHSSRKPFLGAPAATP-HLSLPPG----PSSPP--PPPCPRLLRPPPPPAWLKGPAC 491
Query: 1196 QAQEKHGE-------SQEGKPCPEDLEQTQQRPLCPRER----PRHNFPV------VRSL 1238
+A + GE EG P P PL RE P F V
Sbjct: 492 RAAREDGEILEELFFGTEGPPRPAP------PPLPHREGFLGPPASRFSVGTQDSHTPPT 545
Query: 1239 PPPVHRHSVSGFSEPVGRRPGGPQSLTPLP-------AYPATQKVLQDPQSGEYFVFDLP 1291
PP S + S P GP S P P P Q+PQ L
Sbjct: 546 PPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLA 605
Query: 1292 L---------QVKIKTFYDPETGKYVKVSIPSSEGASPEPPPPDALAAPYVLYPGFQPVP 1342
L Q +F PE+ + +VS P + P PPP AP + PG +P
Sbjct: 606 LPPAPPSSCHQNTSGSFRRPESPR-PRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELP 664
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 45.4 bits (106), Expect = 4e-04
Identities = 103/457 (22%), Positives = 153/457 (33%), Gaps = 91/457 (19%)
Query: 884 SLSSGHKEEELPRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSS 943
S S +EEE E + A N +LG P++ +K A E G+ +
Sbjct: 83 STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS-----MKEKAKAETEKAGKTGN 137
Query: 944 MARMEASQPAPK-GNFPSMPLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIP 1002
S P P G + L G+ R A P A LV+ + GS + AA +
Sbjct: 138 ------SMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMV 191
Query: 1003 TIALPEGDIEDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSP 1062
+ + ED S T +++ A++P G+P
Sbjct: 192 SAGQADSSSEDT-----------------SSSSDETDVEVKASEKILQVRAASAPAKGTP 234
Query: 1063 GESSACSPAASNIWEESSQAPGGPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGG 1122
G+ + +P +SQ G PEE +++S SS T
Sbjct: 235 GKGATPAP-PGKAGAVASQTKAGK---PEEDSESSSEESSDSEEET------------PA 278
Query: 1123 SDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELPAQLERTASKPPAVPPKTEKALR 1182
+ LL+ A S + S + A++PA S R PA P KT A+
Sbjct: 279 AKALLQAKA------SGKTSQVGAASAPAKESPR----------KGAAPAPPGKTGPAV- 321
Query: 1183 RAKKLASKRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPV 1242
AK A KR + Q+ + +S+E P + +P P VR+ P
Sbjct: 322 -AKAQAGKREEDSQSSSEESDSEEEAPA--------------QAKPSGKAPQVRAASAPA 366
Query: 1243 HRHSVSGFSEPVGRRPGGPQSLTPLPAYPATQKVLQDPQ-SGEYFVFDLPLQVKIKTFYD 1301
S G P P+ P A K +D + S E D +
Sbjct: 367 KE------SPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQV 420
Query: 1302 PETGKYVKVSI-------PSSEGASPEPPPPDALAAP 1331
GK +V P +GA P PP A P
Sbjct: 421 KPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATP 457
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 45.4 bits (106), Expect = 4e-04
Identities = 103/457 (22%), Positives = 153/457 (33%), Gaps = 91/457 (19%)
Query: 884 SLSSGHKEEELPRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSS 943
S S +EEE E + A N +LG P++ +K A E G+ +
Sbjct: 83 STSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS-----MKEKAKAETEKAGKTGN 137
Query: 944 MARMEASQPAPK-GNFPSMPLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIP 1002
S P P G + L G+ R A P A LV+ + GS + AA +
Sbjct: 138 ------SMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMV 191
Query: 1003 TIALPEGDIEDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSP 1062
+ + ED S T +++ A++P G+P
Sbjct: 192 SAGQADSSSEDT-----------------SSSSDETDVEVKASEKILQVRAASAPAKGTP 234
Query: 1063 GESSACSPAASNIWEESSQAPGGPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGG 1122
G+ + +P +SQ G PEE +++S SS T
Sbjct: 235 GKGATPAP-PGKAGAVASQTKAGK---PEEDSESSSEESSDSEEET------------PA 278
Query: 1123 SDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELPAQLERTASKPPAVPPKTEKALR 1182
+ LL+ A S + S + A++PA S R PA P KT A+
Sbjct: 279 AKALLQAKA------SGKTSQVGAASAPAKESPR----------KGAAPAPPGKTGPAV- 321
Query: 1183 RAKKLASKRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPV 1242
AK A KR + Q+ + +S+E P + +P P VR+ P
Sbjct: 322 -AKAQAGKREEDSQSSSEESDSEEEAPA--------------QAKPSGKAPQVRAASAPA 366
Query: 1243 HRHSVSGFSEPVGRRPGGPQSLTPLPAYPATQKVLQDPQ-SGEYFVFDLPLQVKIKTFYD 1301
S G P P+ P A K +D + S E D +
Sbjct: 367 KE------SPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQV 420
Query: 1302 PETGKYVKVSI-------PSSEGASPEPPPPDALAAP 1331
GK +V P +GA P PP A P
Sbjct: 421 KPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATP 457
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 45.1 bits (105), Expect = 5e-04
Identities = 128/542 (23%), Positives = 177/542 (32%), Gaps = 70/542 (12%)
Query: 903 PGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQ-GSSMARMEASQPAPKGNFPSM 961
P C E+ G S +++GT + + P G S++ P KG+
Sbjct: 767 PKECPTEDS---GASATASSKGT-----LTYLADSPSPLGVSVSPQTKRPPTKKGSAGPD 818
Query: 962 PLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIPTIALPEG-DIEDQPPPWQP 1020
+G +P +A+ S GS DS A H PT P+G P P
Sbjct: 819 TPIGNLSSPVSPVEASFLPENSLSFQGSKDS---PATTHSPTPPSPKGAPTPSAVTPLSP 875
Query: 1021 ENCW--EEQTPGFKSHFLSTPRAGP--PGRRLVPSERANSPNPGSPGESSACSPAASNIW 1076
+ ++TP L P+ GP P + P+ S +P + + +PA I
Sbjct: 876 KGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSP----KKARATPAPKGIP 931
Query: 1077 EESSQ--APGGPELLPEEPN--QASP---WASSSPARVTRREDLTHALVWEGGSDPLLEL 1129
S AP P P P A+P WA + PA A G+
Sbjct: 932 ASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAA 991
Query: 1130 SAEDLR----TLSPRGSLLDVATSPAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAK 1185
+ + T SP+G+ A +P G + AS PPA P + K A
Sbjct: 992 TPPSPKGGPATPSPKGAPTPPAVTPPSPKGS-PAATPFPKGASTPPAATPPSPKGSPAAT 1050
Query: 1186 KLASKRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLC----PRERPRHNFPVVRSLPPP 1241
L T A S +G P L+ P P+ P P +PP
Sbjct: 1051 PLPKGAPTTPAATLP---SPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPA 1107
Query: 1242 VHRHSVSG-FSEPVGRRPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFY 1300
S G + P + G P + P P P+ P K
Sbjct: 1108 ATPPSPKGGLATPPHK--GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT 1165
Query: 1301 DPETGKYVKVSIPSSEGASPEPPPPDALAAPYVLYPGFQPVPVTALMP-----LRCSSQL 1355
P G P++ A+P P P LA P P P A P L S
Sbjct: 1166 PPPKGA------PTTPAATP-PSPKGGLATPS---PKGAPTTPAATPPSPKGGLATPSPK 1215
Query: 1356 SAPTFLRQGPRASAARARTQSVHESGLQLDPGPHG-DCTPHSAGQRPHGPPQSPGEEGVE 1414
APT A T + GL P P G TP + P G P +P +G
Sbjct: 1216 GAPT----------TPAATPPSPKGGLAT-PSPKGAPTTPAATPPSPKGGPATPPPKGAP 1264
Query: 1415 AP 1416
P
Sbjct: 1265 TP 1266
Score = 40.8 bits (94), Expect = 0.009
Identities = 76/355 (21%), Positives = 112/355 (31%), Gaps = 49/355 (13%)
Query: 949 ASQPAPKGNFPSMPLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIPTIALPE 1008
A+ P+PKG + P G A P + G +A+ G+ + P P+
Sbjct: 1108 ATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP-------SPK 1160
Query: 1009 GDIEDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPG--SPGESS 1066
G + PP P TP L+TP P G P+ SP G +P
Sbjct: 1161 GGLATPPPKGAPTT--PAATPPSPKGGLATP--SPKGAPTTPAATPPSPKGGLATPSPKG 1216
Query: 1067 A-CSPAASNIWEESSQAPGGPELLPEEPNQASPWASSSPARVTRREDLTHALV------- 1118
A +PAA+ + A P+ P P P PA + T
Sbjct: 1217 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKG 1276
Query: 1119 ------WEGGSDPLLELSAEDL---RTLSPRGSLLDVATSPAGTSGRLELPAQLERTASK 1169
+G +P + T P+G+ A +P G P + A
Sbjct: 1277 GLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPP--PKGAPT 1334
Query: 1170 PPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRERPR 1229
PPAV P + K T S+ G P +++ P P P
Sbjct: 1335 PPAVTPPSPKG-------------TPTLPATTPSSKGGPTTP----SSKEGPTPPAATPS 1377
Query: 1230 HNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPAYPATQKVLQDPQSGE 1284
H + P P ++ P S PA P T++ P G+
Sbjct: 1378 HKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGD 1432
Score = 38.1 bits (87), Expect = 0.061
Identities = 90/404 (22%), Positives = 135/404 (33%), Gaps = 50/404 (12%)
Query: 949 ASQPAPKGNFPSMPLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIPTIALPE 1008
A+ P+PKG + G A P + G +A+ G+ + P P+
Sbjct: 1200 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP-------SPK 1252
Query: 1009 GDIEDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLV--PSER---ANSPNPGSPG 1063
G PP P P K + P G P +V PS + A SP G+P
Sbjct: 1253 GGPATPPPKGAPTPP-AATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPT 1311
Query: 1064 ESSAC--SPAASNIWEESSQAPGGPELLPEEPNQASPWASSSPARVTRREDLTHALVWEG 1121
+A SP S AP P + P P +++P + + T EG
Sbjct: 1312 PPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTP---SSKGGPTTPSSKEG 1368
Query: 1122 GSDPLLELSAEDLRTLSP----RGSLLDVATSPAGTSGRLELPAQLERTASKPPAVPPKT 1177
+ P S + ++P RG + SP G PA + + K PA P
Sbjct: 1369 PTPPAATPSHKGGPAMTPPSPKRGPAI---PSPKGDP---TSPAVIPLSPKKAPATPVTR 1422
Query: 1178 EKALRRAKKLASKRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRERPRHNFPVVRS 1237
E A +K + T + +K + K P ++ P P P P +
Sbjct: 1423 EGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPA-TPSSKGDPTLPAVTP----PSPKE 1477
Query: 1238 LPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPA--------YPATQKVLQDP--QSGEYFV 1287
PP + + S P LPA PAT +DP +
Sbjct: 1478 --PPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLS 1535
Query: 1288 FDLPLQVKIKTFYDPETGKYVKVSIPSSEGASPEPPPPDALAAP 1331
P + K P +++PS + P P +A A P
Sbjct: 1536 KKTPATLAPKEALIPPA-----MTVPSPKKTPAIPTPKEAPATP 1574
Score = 33.5 bits (75), Expect = 1.5
Identities = 96/489 (19%), Positives = 155/489 (31%), Gaps = 49/489 (10%)
Query: 952 PAPKGNFPSMPLVGEGDRVKAPPDAAPGLVASNCKSGSADSGKLAAPWHIPTIALPEGDI 1011
P+PKG + P G A P + G + G+ + P T LP
Sbjct: 1295 PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTP 1354
Query: 1012 EDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPG--ESSACS 1069
+ P P + P P PP + P+ + +P SP S
Sbjct: 1355 SSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKK 1414
Query: 1070 PAASNIWEESSQAPGGPELLP---------EEPNQASPWASSSPARVTRREDLTHALVWE 1120
A+ + E + P +L P + P ++P PA + + D T V
Sbjct: 1415 APATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAP--KGGPATPSSKGDPTLPAV-- 1470
Query: 1121 GGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELPAQLERTASKPPAVPPKTEKA 1180
P + ++ S +PA G LPA + + + PA P
Sbjct: 1471 ---TPPSPKEPPAPKQVATSSSPKKAPATPA-PMGAPTLPAVIPSSPKEVPATPSSRRDP 1526
Query: 1181 LRRAKKLASKRRKTDQA-QEKHGESQEGKPCPED---LEQTQQRPLCPRERPRHNFPVV- 1235
+ L SK+ A +E P P+ + ++ P P + + P V
Sbjct: 1527 IAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVT 1586
Query: 1236 ----RSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPL-----PAYPATQKVLQDPQSGEYF 1286
+ P P + P + P ++TP PA PA + P
Sbjct: 1587 PSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSS 1646
Query: 1287 VFDLPLQVKIKTFYDPETGKYVKVSIPSSEG--------ASPEPPPPDALAAPYVLYPGF 1338
+ D P T T +P+ +G +P P + AP G
Sbjct: 1647 LKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAP--TRKGP 1704
Query: 1339 QPVPVTALMPLRCSSQLSAPTFLRQGPRASAARARTQSVHESGLQLDPGPHGDCTPHSAG 1398
Q +A P C + +GP ++ A A V + + G +P
Sbjct: 1705 QTKKSSATSPPICPDPSAKNG--SKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSP---- 1758
Query: 1399 QRPHGPPQS 1407
+ P PP+S
Sbjct: 1759 KGPLAPPES 1767
>gi|33667044 ABI gene family, member 3 (NESH) binding protein [Homo
sapiens]
Length = 1075
Score = 43.9 bits (102), Expect = 0.001
Identities = 71/332 (21%), Positives = 110/332 (33%), Gaps = 67/332 (20%)
Query: 1131 AEDLRTLSPRGSLLDVATSPAGTSGRLELPAQLERTASKP-PAVPPKTEKALRRAKK-LA 1188
+ED + L P+ + DV +SP TS E+ T+ + ++PPKT + L + + LA
Sbjct: 376 SEDSKVLQPQTATYDVFSSPT-TSDEPEISDSYTATSDRILDSIPPKTSRTLEQPRATLA 434
Query: 1189 SKRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRERPRHN---------------FP 1233
+ + S E +P +QT P P+ RPR P
Sbjct: 435 PSETPFVPQKLEIFTSPEMQPTTPAPQQTTSIPSTPKRRPRPKPPRTKPERTTSAGTITP 494
Query: 1234 VVRSLPPPVHRHSVSGFSEPVGRRPGGPQS---------------------LTPLPAYPA 1272
+ P P G ++ + +P P S +P P P
Sbjct: 495 KISKSPEPTWTTPAPGKTQFISLKPKIPLSPEVTHTKPAPKQTPRAPPKPKTSPRPRIPQ 554
Query: 1273 TQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSI-------PSSEGASPEPPPP 1325
TQ V + PQ + K KT PE P E + EP P
Sbjct: 555 TQPVPKVPQR---------VTAKPKTSPSPEVSYTTPAPKDVLLPHKPYPEVSQSEPAPL 605
Query: 1326 DALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASAARARTQSVHESGLQLD 1385
+ P++ P L + Q + F + PR + TQ+ H +
Sbjct: 606 ETRGIPFIPMISPSPSQEELQTTLEETDQSTQEPFTTKIPRTTELAKTTQAPHRFYTTVR 665
Query: 1386 PGPHGDCTPHSAGQRPH---GPPQSPGEEGVE 1414
P +PH G Q+P G +
Sbjct: 666 P---------RTSDKPHIRPGVKQAPRPSGAD 688
>gi|18079216 CASK interacting protein 1 [Homo sapiens]
Length = 1431
Score = 43.5 bits (101), Expect = 0.001
Identities = 44/142 (30%), Positives = 58/142 (40%), Gaps = 20/142 (14%)
Query: 1160 PAQLERTASKPPA-VPPKTEKALRRAKKLASKRRKTDQAQEKHGESQEGKPCPED----- 1213
PA++ T KP + +PP R+ L + R +QE G+ G P
Sbjct: 668 PAEVGPTTEKPSSHLPPTPRATTRQDSSLGGRARHMSSSQELLGDGPPGPSSPMSRSQEY 727
Query: 1214 -LEQTQQRPLCPRE-RP-RHNFPVVRSLPPPVHRH-------SVSGFS---EPVGRRPGG 1260
L++ PRE RP RH + R+ PPV S F+ P RPG
Sbjct: 728 LLDEGPAPGTPPREARPGRHGHSIKRASVPPVPGKPRQVLPPGTSHFTPPQTPTKTRPGS 787
Query: 1261 PQSL-TPLPAYPATQKVLQDPQ 1281
PQ+L P PAT KV PQ
Sbjct: 788 PQALGGPHGPAPATAKVKPTPQ 809
Score = 40.4 bits (93), Expect = 0.012
Identities = 151/614 (24%), Positives = 201/614 (32%), Gaps = 135/614 (21%)
Query: 864 ATPVIKP---IMLPLLRTMS---LEDSLSSGHKEEELPRPEWGEDPGFCAPENQDILGTS 917
AT +KP ++ P R MS L S + LP+P GE G AP G +
Sbjct: 800 ATAKVKPTPQLLPPTERPMSPRSLPQSPTHRGFAYVLPQPVEGE-VGPAAP------GPA 852
Query: 918 TPTNTRGTRVKCMANEVMEDPGQ----GSSMARMEASQPAPKGNFPSMPL---------- 963
P C+ E +PG+ S+ R AS P+ + +P
Sbjct: 853 PPPVPTAVPTLCLPPEADAEPGRPKKRAHSLNRYAASDSEPERDELLVPAAAGPYATVQR 912
Query: 964 -VGEGDRVKAPPDAAPGLVASNCKS-GSADSGKLAAPWHIPTIALPEGDIEDQP-PPWQP 1020
VG V+AP A + S + G P + AL ++ D+P P +P
Sbjct: 913 RVGRSHSVRAPAGADKNVNRSQSFAVRPRKKGPPPPPPKRSSSALASANLADEPVPDAEP 972
Query: 1021 ENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPG--ESSACSPAASNIWEE 1078
E+ G RA S+ A S + GS G +S A S+I
Sbjct: 973 ED-------GLLGVRAQCRRA---------SDLAGSVDTGSAGSVKSIAAMLELSSIGGG 1016
Query: 1079 SSQAPGGPELLPEEPNQASPWASSSPARV-TRREDLTHALVWEGGSDPLLELSAEDLRTL 1137
A PE P P ASP P RV T + H G + + RTL
Sbjct: 1017 GRAARRPPEGHPT-PRPASP----EPGRVATVLASVKHKEAIGPGGEVV-----NRRRTL 1066
Query: 1138 S-PRGSLLDVATSPAGTSG-------------RLELPAQLERTASKPPAVPPKTEKALRR 1183
S P LL A G S R P++ E PP + L+R
Sbjct: 1067 SGPVTGLLATARRGPGESADPGPFVEDGTGRQRPRGPSKGEAGVEGPPLAKVEASATLKR 1126
Query: 1184 AKKLASKRRK----------TDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRERPRHNFP 1233
+ +++ T + + K E + G P L R RP
Sbjct: 1127 RIRAKQNQQENVKFILTESDTVKRRPKAKEREAGPEPPPPLSVYHNGTGTVRRRPASEQA 1186
Query: 1234 VVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQ 1293
LPPP P P P L LP P + + P + Q
Sbjct: 1187 GPPELPPP----------PPPAEPP--PTDLAHLPPLPPPEGEARKPAKPPVSPKPVLTQ 1234
Query: 1294 VKIKTFYDPE-TGKYVKVSIPSSEGA----------SPEPPPPDALAAPYVLYPGFQPVP 1342
K P T K V + P S SP+PPPP AP +PV
Sbjct: 1235 PVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPP--TAP-------KPVK 1285
Query: 1343 VTALMPLRCSSQLSAPTFLRQGPRASAARARTQSVHESGLQLDPGPHGDCTPHSAGQRPH 1402
A +P + AP+ RQ P A L PG TP S G P
Sbjct: 1286 AVAGLPSGSAGPSPAPSPARQPPAA--------------LAKPPG-----TPPSLGASPA 1326
Query: 1403 GPPQSPGEEGVEAP 1416
PP SPG + P
Sbjct: 1327 KPP-SPGAPALHVP 1339
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 43.1 bits (100), Expect = 0.002
Identities = 72/323 (22%), Positives = 113/323 (34%), Gaps = 41/323 (12%)
Query: 893 ELPRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQP 952
E P P E+P AP +TP T K A ++P + E +
Sbjct: 520 EEPTPTTPEEP---APTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK---ETAPT 573
Query: 953 APKGNFPSMPLVGEGDRVK--APPDAAPGLV----ASNCKSGSADSGKLAAPWHIPTIAL 1006
PKG P+ K AP + AP ++ C + + K AP T
Sbjct: 574 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP---TTPKE 630
Query: 1007 PEGDIEDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVP-------SERANSPNP 1059
P +P P P+ K +TP+ P + L P S ++ P P
Sbjct: 631 PAPTTPKEPAPTTPKGT---APTTLKEPAPTTPKKPAP-KELAPTTTKGPTSTTSDKPAP 686
Query: 1060 GSPGESSACSPAASNIWEESSQAPGGPELLPEEPNQAS-PWASSSPARVTRREDLTHALV 1118
+P E++ +P AP PE P ++ S P + P + + D
Sbjct: 687 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPD------ 740
Query: 1119 WEGGSDPLLELSAEDLRTL---SPRGSLLDVATSPAGTSGRLELPAQLERTASKPPAVPP 1175
+ ELSAE SP+ + +PA T + A+ + T P
Sbjct: 741 -----ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE 795
Query: 1176 KTEKALRRAKKLASKRRKTDQAQ 1198
T A + K+ A+ KT +++
Sbjct: 796 TTTAAPKMTKETATTTEKTTESK 818
Score = 40.8 bits (94), Expect = 0.009
Identities = 83/407 (20%), Positives = 128/407 (31%), Gaps = 53/407 (13%)
Query: 209 SYQPGRKHGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGT 268
S++ GR+ K + C SF D K P+P PV E G G
Sbjct: 36 SFERGRECDCDAQCKKYDKCCPDYESFCAEVKDNKKNRTKKKPTPK-PPVVDEAGSG--- 91
Query: 269 FLHSENSAFESWNAHQPKLLERKDTAGTVPESKAPKHYGDTTLLREPCPPERTVSPCQVQ 328
L+ D T P++ +H +T P T P +
Sbjct: 92 -------------------LDNGDFKVTTPDTSTTQHNKVST-----SPKITTAKPINPR 127
Query: 329 ASCSQEENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPSSQPDSQEKP--AQPPWRKPKT 386
S + +L+ + ++ + + D +EK A+ KT
Sbjct: 128 PSLPPNSDTSKETSLTVN-----KETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 182
Query: 387 GKKGKESLQDTLEE---KTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNI 443
K L + K +T +GP L T P + A P EP P
Sbjct: 183 SAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT----PTTIK 238
Query: 444 SKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNL 503
S TP P+ SA + P E P+ + KEP+ +++ + S
Sbjct: 239 SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 298
Query: 504 KD----VRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESPPNELSKE 559
K+ K+ T P E T K+ + P +E P K
Sbjct: 299 KEPAPTTPKKPAPTTPKEPAPTTPKEPT--PTTPKEPAPTTKEPAPTTPKEPAPTAPKKP 356
Query: 560 RPADDPTASHINPQKD-PTA----DPSEPSADSYLTLSTAPTIAKAP 601
P + P++ PT P+ P + T +APT K P
Sbjct: 357 APTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 403
Score = 38.5 bits (88), Expect = 0.047
Identities = 69/347 (19%), Positives = 111/347 (31%), Gaps = 23/347 (6%)
Query: 1025 EEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPG 1084
+E TP +TP+ P P P + E + +P AP
Sbjct: 230 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 289
Query: 1085 GPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLEL-SAEDLRTLSPRGSL 1143
+ P P + +P PA T +E + P + ++ +P+
Sbjct: 290 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 349
Query: 1144 LDVATSPAGTSGRLELPAQLER---TASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEK 1200
PA T+ + P + T +K P+ E A K + ++ K
Sbjct: 350 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 409
Query: 1201 HGESQEGKPCPEDLEQTQQRPLCPRE----RPRHNFPVVRSLPPPV--HRHSVSGFSEPV 1254
+ +P P + + P P+E P+ P P P + + +P
Sbjct: 410 SAPTTPKEPSPTTTK--EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 467
Query: 1255 GRRPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPS 1314
P P TP P T K L P + E P + P T + + + P
Sbjct: 468 PTTPKEPAPTTPKETAPTTPKKL-TPTTPEKLAPTTPEKPA------PTTPEELAPTTP- 519
Query: 1315 SEGASPEPPPPDALAAPYVLYPGF--QPVPVTALMPLRCSSQLSAPT 1359
E +P P A P P +P P T P + + APT
Sbjct: 520 -EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 565
Score = 38.1 bits (87), Expect = 0.061
Identities = 106/545 (19%), Positives = 168/545 (30%), Gaps = 51/545 (9%)
Query: 96 AATFQQLPKYVQGEEKYPKTSPPPTPVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTES 155
A T + P +E P T PTP + P + + P
Sbjct: 302 APTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK--------------- 346
Query: 156 QRCESRPTASKPPALKNPPKFAPLPENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRK 215
E PTA K PA P + AP + A T + E S T P
Sbjct: 347 ---EPAPTAPKKPAPTTPKEPAPTTPK------EPAPTTTK----EPSPTTPKEPAPTTT 393
Query: 216 HGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENS 275
++K P S+ P + T + P+ +P P + T
Sbjct: 394 KSAPTTTKEPAPTTTKSAPTTP-KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 452
Query: 276 AFESWNAHQPKLLERKDTAGTVPESKA---PKHYGDTTLLR-EPCPPERTVSPCQVQASC 331
+P K A T P+ A PK TT + P PE+ ++P +
Sbjct: 453 T----TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK-LAPTTPEKPA 507
Query: 332 SQEENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPSSQPDSQEKPAQPPWRKPKTGKKGK 391
LA P +P ++ P++ ++PA P K K
Sbjct: 508 PTTPEELAPTTPEEPTPTTPEEPAPTT------PKAAAPNTPKEPA-PTTPKEPAPTTPK 560
Query: 392 ESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISKLLTPII 451
E T +E T +G T P + A + P +P P
Sbjct: 561 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKEPTSTTCDKPAPTT 619
Query: 452 PSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLKDVRKRVK 511
P K + +PA TP P + P+ + K P+ K
Sbjct: 620 P-KGTAPTTPKEPAPTTPKEPAPTTP-KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPT 677
Query: 512 STYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESPP--NELSKERPADDPTASH 569
ST S P ++T + P + P E PP +E+S +PT H
Sbjct: 678 STTSDKP-APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 736
Query: 570 INPQKDPTADPSEPSADSYLTLSTAPTIAKAPFYVNGEAAERSSYENKEVEGELEMGPAG 629
+P + +EP+ + P + + ++ ++K E +L P
Sbjct: 737 KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPET 796
Query: 630 SSWCP 634
++ P
Sbjct: 797 TTAAP 801
Score = 38.1 bits (87), Expect = 0.061
Identities = 107/521 (20%), Positives = 157/521 (30%), Gaps = 73/521 (14%)
Query: 96 AATFQQLPKYVQGEEKYPKTSPPPTPVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTES 155
A T + P +E P T P P + P + + T K T +
Sbjct: 349 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 408
Query: 156 QRC-----ESRPTASKPPALKNPPKFAP-LPENSVNFCFDSAFLTVRRVPAEVSNTHQNS 209
+ E PT +K PA P + AP P+ T + PA +
Sbjct: 409 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT----- 463
Query: 210 YQPGRKHGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGTF 269
K + K P ++ T T E P+ KP P T
Sbjct: 464 -----KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT- 517
Query: 270 LHSENSAFESWNAHQPKLLERKDTAGTVPESKAPKHYGD--TTLLREPCP-PERTVSPCQ 326
+P ++ A T P++ AP + T +EP P + +P
Sbjct: 518 -----------TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 566
Query: 327 VQASCSQEENRLAAGALSTSIPWGCRDPGAQVFA-VEGKAPSSQPDSQEKPAQPPWRKPK 385
+ + A L P + P + A K P+S + P P P
Sbjct: 567 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT 626
Query: 386 TGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISK 445
T KE T +E T +G T P + A + P P S
Sbjct: 627 T---PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSD 682
Query: 446 LLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLKD 505
P P K + +PA TP P + P+ + +K P+ +
Sbjct: 683 KPAPTTP-KETAPTTPKEPAPTTPKKPAPTTP-ETPPPTTSEVSTPTTTKEPTTIH---- 736
Query: 506 VRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESP--PNELSKERPAD 563
KS S+P L EP P LE SP P + + PA
Sbjct: 737 -----KSPDESTPELSA-------------EPT------PKALENSPKEPGVPTTKTPAA 772
Query: 564 -----DPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAK 599
TA ++D P +A +T TA T K
Sbjct: 773 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK 813
Score = 38.1 bits (87), Expect = 0.061
Identities = 87/425 (20%), Positives = 134/425 (31%), Gaps = 53/425 (12%)
Query: 895 PRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAP 954
P P ++P P+ T + T P + S E + P
Sbjct: 372 PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 431
Query: 955 KGNFPSMPLVGEGDRVKAPPDAAPGLVA-SNCKSGSADSGKLAAPWH----IPTI----- 1004
K P+ P K P P A + K + + K AP PT
Sbjct: 432 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 491
Query: 1005 -ALPEG---DIEDQPPPWQPENCW----EEQTPGFKSHFL-STPRAGPPGRRLVPSERA- 1054
PE ++P P PE EE TP +TP+A P P+
Sbjct: 492 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 551
Query: 1055 --------NSPNPGSPGESSACSP---AASNIWEESSQAPGGP---ELLPEEPNQASPWA 1100
P P +P E++ +P A + + E + P P EL P + +
Sbjct: 552 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 611
Query: 1101 SSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELP 1160
PA T + +P E T +P+G+ PA T+ + P
Sbjct: 612 CDKPAPTTPKGTAPTT-----PKEPAPTTPKEPAPT-TPKGTAPTTLKEPAPTTPKKPAP 665
Query: 1161 AQLERTASKPPAVPPKTEKALRRAKKLA--SKRRKTDQAQEKHGESQEGKPCPEDLE--- 1215
+L T +K P + A K+ A + + +K + P P E
Sbjct: 666 KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 725
Query: 1216 -QTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPAYPATQ 1274
T + P + P + P + + P P E + PG P + TP P
Sbjct: 726 PTTTKEPTTIHKSPDESTPELSAEPTP-------KALENSPKEPGVPTTKTPAATKPEMT 778
Query: 1275 KVLQD 1279
+D
Sbjct: 779 TTAKD 783
Score = 35.0 bits (79), Expect = 0.52
Identities = 64/281 (22%), Positives = 86/281 (30%), Gaps = 36/281 (12%)
Query: 1151 AGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQE-KHGESQEGKP 1209
A TS L P T +K PA+ E K+ AS K K + +P
Sbjct: 188 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 247
Query: 1210 CPEDLEQTQQRPLCPRE------------RPRHNFPVVRSLPPPVHRHSVSGF-SEPVGR 1256
P T+ P P+E P+ P P P S EP
Sbjct: 248 APTT---TKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 304
Query: 1257 RPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPSSE 1316
P P TP P T K +P P K P T + +
Sbjct: 305 TPKKPAPTTPKEPAPTTPK---EPT---------PTTPKEPA---PTTKEPAPTTPKEPA 349
Query: 1317 GASPEPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASAARARTQS 1376
+P+ P P P P +P P T P + + APT + P + A T +
Sbjct: 350 PTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 408
Query: 1377 VHESGLQLDPGPHGDCTPHSAGQRPHGP-PQSPGEEGVEAP 1416
+P P T A P P P +P + P
Sbjct: 409 KSAPTTPKEPSP--TTTKEPAPTTPKEPAPTTPKKPAPTTP 447
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 43.1 bits (100), Expect = 0.002
Identities = 72/323 (22%), Positives = 113/323 (34%), Gaps = 41/323 (12%)
Query: 893 ELPRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQP 952
E P P E+P AP +TP T K A ++P + E +
Sbjct: 561 EEPTPTTPEEP---APTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK---ETAPT 614
Query: 953 APKGNFPSMPLVGEGDRVK--APPDAAPGLV----ASNCKSGSADSGKLAAPWHIPTIAL 1006
PKG P+ K AP + AP ++ C + + K AP T
Sbjct: 615 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP---TTPKE 671
Query: 1007 PEGDIEDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVP-------SERANSPNP 1059
P +P P P+ K +TP+ P + L P S ++ P P
Sbjct: 672 PAPTTPKEPAPTTPKGT---APTTLKEPAPTTPKKPAP-KELAPTTTKGPTSTTSDKPAP 727
Query: 1060 GSPGESSACSPAASNIWEESSQAPGGPELLPEEPNQAS-PWASSSPARVTRREDLTHALV 1118
+P E++ +P AP PE P ++ S P + P + + D
Sbjct: 728 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPD------ 781
Query: 1119 WEGGSDPLLELSAEDLRTL---SPRGSLLDVATSPAGTSGRLELPAQLERTASKPPAVPP 1175
+ ELSAE SP+ + +PA T + A+ + T P
Sbjct: 782 -----ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE 836
Query: 1176 KTEKALRRAKKLASKRRKTDQAQ 1198
T A + K+ A+ KT +++
Sbjct: 837 TTTAAPKMTKETATTTEKTTESK 859
Score = 40.8 bits (94), Expect = 0.009
Identities = 83/407 (20%), Positives = 128/407 (31%), Gaps = 53/407 (13%)
Query: 209 SYQPGRKHGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGT 268
S++ GR+ K + C SF D K P+P PV E G G
Sbjct: 77 SFERGRECDCDAQCKKYDKCCPDYESFCAEVKDNKKNRTKKKPTPK-PPVVDEAGSG--- 132
Query: 269 FLHSENSAFESWNAHQPKLLERKDTAGTVPESKAPKHYGDTTLLREPCPPERTVSPCQVQ 328
L+ D T P++ +H +T P T P +
Sbjct: 133 -------------------LDNGDFKVTTPDTSTTQHNKVST-----SPKITTAKPINPR 168
Query: 329 ASCSQEENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPSSQPDSQEKP--AQPPWRKPKT 386
S + +L+ + ++ + + D +EK A+ KT
Sbjct: 169 PSLPPNSDTSKETSLTVN-----KETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 223
Query: 387 GKKGKESLQDTLEE---KTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNI 443
K L + K +T +GP L T P + A P EP P
Sbjct: 224 SAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT----PTTIK 279
Query: 444 SKLLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNL 503
S TP P+ SA + P E P+ + KEP+ +++ + S
Sbjct: 280 SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 339
Query: 504 KD----VRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESPPNELSKE 559
K+ K+ T P E T K+ + P +E P K
Sbjct: 340 KEPAPTTPKKPAPTTPKEPAPTTPKEPT--PTTPKEPAPTTKEPAPTTPKEPAPTAPKKP 397
Query: 560 RPADDPTASHINPQKD-PTA----DPSEPSADSYLTLSTAPTIAKAP 601
P + P++ PT P+ P + T +APT K P
Sbjct: 398 APTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 444
Score = 38.5 bits (88), Expect = 0.047
Identities = 69/347 (19%), Positives = 111/347 (31%), Gaps = 23/347 (6%)
Query: 1025 EEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPG 1084
+E TP +TP+ P P P + E + +P AP
Sbjct: 271 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 330
Query: 1085 GPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLEL-SAEDLRTLSPRGSL 1143
+ P P + +P PA T +E + P + ++ +P+
Sbjct: 331 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 390
Query: 1144 LDVATSPAGTSGRLELPAQLER---TASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEK 1200
PA T+ + P + T +K P+ E A K + ++ K
Sbjct: 391 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 450
Query: 1201 HGESQEGKPCPEDLEQTQQRPLCPRE----RPRHNFPVVRSLPPPV--HRHSVSGFSEPV 1254
+ +P P + + P P+E P+ P P P + + +P
Sbjct: 451 SAPTTPKEPSPTTTK--EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 508
Query: 1255 GRRPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPS 1314
P P TP P T K L P + E P + P T + + + P
Sbjct: 509 PTTPKEPAPTTPKETAPTTPKKL-TPTTPEKLAPTTPEKPA------PTTPEELAPTTP- 560
Query: 1315 SEGASPEPPPPDALAAPYVLYPGF--QPVPVTALMPLRCSSQLSAPT 1359
E +P P A P P +P P T P + + APT
Sbjct: 561 -EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 606
Score = 38.1 bits (87), Expect = 0.061
Identities = 106/545 (19%), Positives = 168/545 (30%), Gaps = 51/545 (9%)
Query: 96 AATFQQLPKYVQGEEKYPKTSPPPTPVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTES 155
A T + P +E P T PTP + P + + P
Sbjct: 343 APTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK--------------- 387
Query: 156 QRCESRPTASKPPALKNPPKFAPLPENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRK 215
E PTA K PA P + AP + A T + E S T P
Sbjct: 388 ---EPAPTAPKKPAPTTPKEPAPTTPK------EPAPTTTK----EPSPTTPKEPAPTTT 434
Query: 216 HGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENS 275
++K P S+ P + T + P+ +P P + T
Sbjct: 435 KSAPTTTKEPAPTTTKSAPTTP-KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 493
Query: 276 AFESWNAHQPKLLERKDTAGTVPESKA---PKHYGDTTLLR-EPCPPERTVSPCQVQASC 331
+P K A T P+ A PK TT + P PE+ ++P +
Sbjct: 494 T----TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK-LAPTTPEKPA 548
Query: 332 SQEENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPSSQPDSQEKPAQPPWRKPKTGKKGK 391
LA P +P ++ P++ ++PA P K K
Sbjct: 549 PTTPEELAPTTPEEPTPTTPEEPAPTT------PKAAAPNTPKEPA-PTTPKEPAPTTPK 601
Query: 392 ESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISKLLTPII 451
E T +E T +G T P + A + P +P P
Sbjct: 602 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKEPTSTTCDKPAPTT 660
Query: 452 PSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLKDVRKRVK 511
P K + +PA TP P + P+ + K P+ K
Sbjct: 661 P-KGTAPTTPKEPAPTTPKEPAPTTP-KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPT 718
Query: 512 STYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESPP--NELSKERPADDPTASH 569
ST S P ++T + P + P E PP +E+S +PT H
Sbjct: 719 STTSDKP-APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 777
Query: 570 INPQKDPTADPSEPSADSYLTLSTAPTIAKAPFYVNGEAAERSSYENKEVEGELEMGPAG 629
+P + +EP+ + P + + ++ ++K E +L P
Sbjct: 778 KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPET 837
Query: 630 SSWCP 634
++ P
Sbjct: 838 TTAAP 842
Score = 38.1 bits (87), Expect = 0.061
Identities = 107/521 (20%), Positives = 157/521 (30%), Gaps = 73/521 (14%)
Query: 96 AATFQQLPKYVQGEEKYPKTSPPPTPVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTES 155
A T + P +E P T P P + P + + T K T +
Sbjct: 390 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 449
Query: 156 QRC-----ESRPTASKPPALKNPPKFAP-LPENSVNFCFDSAFLTVRRVPAEVSNTHQNS 209
+ E PT +K PA P + AP P+ T + PA +
Sbjct: 450 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT----- 504
Query: 210 YQPGRKHGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGTF 269
K + K P ++ T T E P+ KP P T
Sbjct: 505 -----KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT- 558
Query: 270 LHSENSAFESWNAHQPKLLERKDTAGTVPESKAPKHYGD--TTLLREPCP-PERTVSPCQ 326
+P ++ A T P++ AP + T +EP P + +P
Sbjct: 559 -----------TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 607
Query: 327 VQASCSQEENRLAAGALSTSIPWGCRDPGAQVFA-VEGKAPSSQPDSQEKPAQPPWRKPK 385
+ + A L P + P + A K P+S + P P P
Sbjct: 608 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT 667
Query: 386 TGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISK 445
T KE T +E T +G T P + A + P P S
Sbjct: 668 T---PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSD 723
Query: 446 LLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLKD 505
P P K + +PA TP P + P+ + +K P+ +
Sbjct: 724 KPAPTTP-KETAPTTPKEPAPTTPKKPAPTTP-ETPPPTTSEVSTPTTTKEPTTIH---- 777
Query: 506 VRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESP--PNELSKERPAD 563
KS S+P L EP P LE SP P + + PA
Sbjct: 778 -----KSPDESTPELSA-------------EPT------PKALENSPKEPGVPTTKTPAA 813
Query: 564 -----DPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAK 599
TA ++D P +A +T TA T K
Sbjct: 814 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK 854
Score = 38.1 bits (87), Expect = 0.061
Identities = 87/425 (20%), Positives = 134/425 (31%), Gaps = 53/425 (12%)
Query: 895 PRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAP 954
P P ++P P+ T + T P + S E + P
Sbjct: 413 PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 472
Query: 955 KGNFPSMPLVGEGDRVKAPPDAAPGLVA-SNCKSGSADSGKLAAPWH----IPTI----- 1004
K P+ P K P P A + K + + K AP PT
Sbjct: 473 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 532
Query: 1005 -ALPEG---DIEDQPPPWQPENCW----EEQTPGFKSHFL-STPRAGPPGRRLVPSERA- 1054
PE ++P P PE EE TP +TP+A P P+
Sbjct: 533 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 592
Query: 1055 --------NSPNPGSPGESSACSP---AASNIWEESSQAPGGP---ELLPEEPNQASPWA 1100
P P +P E++ +P A + + E + P P EL P + +
Sbjct: 593 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 652
Query: 1101 SSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELP 1160
PA T + +P E T +P+G+ PA T+ + P
Sbjct: 653 CDKPAPTTPKGTAPTT-----PKEPAPTTPKEPAPT-TPKGTAPTTLKEPAPTTPKKPAP 706
Query: 1161 AQLERTASKPPAVPPKTEKALRRAKKLA--SKRRKTDQAQEKHGESQEGKPCPEDLE--- 1215
+L T +K P + A K+ A + + +K + P P E
Sbjct: 707 KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 766
Query: 1216 -QTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPAYPATQ 1274
T + P + P + P + + P P E + PG P + TP P
Sbjct: 767 PTTTKEPTTIHKSPDESTPELSAEPTP-------KALENSPKEPGVPTTKTPAATKPEMT 819
Query: 1275 KVLQD 1279
+D
Sbjct: 820 TTAKD 824
Score = 35.0 bits (79), Expect = 0.52
Identities = 64/281 (22%), Positives = 86/281 (30%), Gaps = 36/281 (12%)
Query: 1151 AGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQE-KHGESQEGKP 1209
A TS L P T +K PA+ E K+ AS K K + +P
Sbjct: 229 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 288
Query: 1210 CPEDLEQTQQRPLCPRE------------RPRHNFPVVRSLPPPVHRHSVSGF-SEPVGR 1256
P T+ P P+E P+ P P P S EP
Sbjct: 289 APTT---TKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 345
Query: 1257 RPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPSSE 1316
P P TP P T K +P P K P T + +
Sbjct: 346 TPKKPAPTTPKEPAPTTPK---EPT---------PTTPKEPA---PTTKEPAPTTPKEPA 390
Query: 1317 GASPEPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASAARARTQS 1376
+P+ P P P P +P P T P + + APT + P + A T +
Sbjct: 391 PTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 449
Query: 1377 VHESGLQLDPGPHGDCTPHSAGQRPHGP-PQSPGEEGVEAP 1416
+P P T A P P P +P + P
Sbjct: 450 KSAPTTPKEPSP--TTTKEPAPTTPKEPAPTTPKKPAPTTP 488
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 43.1 bits (100), Expect = 0.002
Identities = 72/323 (22%), Positives = 113/323 (34%), Gaps = 41/323 (12%)
Query: 893 ELPRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQP 952
E P P E+P AP +TP T K A ++P + E +
Sbjct: 613 EEPTPTTPEEP---APTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK---ETAPT 666
Query: 953 APKGNFPSMPLVGEGDRVK--APPDAAPGLV----ASNCKSGSADSGKLAAPWHIPTIAL 1006
PKG P+ K AP + AP ++ C + + K AP T
Sbjct: 667 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP---TTPKE 723
Query: 1007 PEGDIEDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVP-------SERANSPNP 1059
P +P P P+ K +TP+ P + L P S ++ P P
Sbjct: 724 PAPTTPKEPAPTTPKGT---APTTLKEPAPTTPKKPAP-KELAPTTTKGPTSTTSDKPAP 779
Query: 1060 GSPGESSACSPAASNIWEESSQAPGGPELLPEEPNQAS-PWASSSPARVTRREDLTHALV 1118
+P E++ +P AP PE P ++ S P + P + + D
Sbjct: 780 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPD------ 833
Query: 1119 WEGGSDPLLELSAEDLRTL---SPRGSLLDVATSPAGTSGRLELPAQLERTASKPPAVPP 1175
+ ELSAE SP+ + +PA T + A+ + T P
Sbjct: 834 -----ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE 888
Query: 1176 KTEKALRRAKKLASKRRKTDQAQ 1198
T A + K+ A+ KT +++
Sbjct: 889 TTTAAPKMTKETATTTEKTTESK 911
Score = 38.5 bits (88), Expect = 0.047
Identities = 69/347 (19%), Positives = 111/347 (31%), Gaps = 23/347 (6%)
Query: 1025 EEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPG 1084
+E TP +TP+ P P P + E + +P AP
Sbjct: 323 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 382
Query: 1085 GPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLEL-SAEDLRTLSPRGSL 1143
+ P P + +P PA T +E + P + ++ +P+
Sbjct: 383 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 442
Query: 1144 LDVATSPAGTSGRLELPAQLER---TASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEK 1200
PA T+ + P + T +K P+ E A K + ++ K
Sbjct: 443 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 502
Query: 1201 HGESQEGKPCPEDLEQTQQRPLCPRE----RPRHNFPVVRSLPPPV--HRHSVSGFSEPV 1254
+ +P P + + P P+E P+ P P P + + +P
Sbjct: 503 SAPTTPKEPSPTTTK--EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 560
Query: 1255 GRRPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPS 1314
P P TP P T K L P + E P + P T + + + P
Sbjct: 561 PTTPKEPAPTTPKETAPTTPKKL-TPTTPEKLAPTTPEKPA------PTTPEELAPTTP- 612
Query: 1315 SEGASPEPPPPDALAAPYVLYPGF--QPVPVTALMPLRCSSQLSAPT 1359
E +P P A P P +P P T P + + APT
Sbjct: 613 -EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 658
Score = 38.1 bits (87), Expect = 0.061
Identities = 106/545 (19%), Positives = 168/545 (30%), Gaps = 51/545 (9%)
Query: 96 AATFQQLPKYVQGEEKYPKTSPPPTPVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTES 155
A T + P +E P T PTP + P + + P
Sbjct: 395 APTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK--------------- 439
Query: 156 QRCESRPTASKPPALKNPPKFAPLPENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRK 215
E PTA K PA P + AP + A T + E S T P
Sbjct: 440 ---EPAPTAPKKPAPTTPKEPAPTTPK------EPAPTTTK----EPSPTTPKEPAPTTT 486
Query: 216 HGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENS 275
++K P S+ P + T + P+ +P P + T
Sbjct: 487 KSAPTTTKEPAPTTTKSAPTTP-KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 545
Query: 276 AFESWNAHQPKLLERKDTAGTVPESKA---PKHYGDTTLLR-EPCPPERTVSPCQVQASC 331
+P K A T P+ A PK TT + P PE+ ++P +
Sbjct: 546 T----TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK-LAPTTPEKPA 600
Query: 332 SQEENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPSSQPDSQEKPAQPPWRKPKTGKKGK 391
LA P +P ++ P++ ++PA P K K
Sbjct: 601 PTTPEELAPTTPEEPTPTTPEEPAPTT------PKAAAPNTPKEPA-PTTPKEPAPTTPK 653
Query: 392 ESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISKLLTPII 451
E T +E T +G T P + A + P +P P
Sbjct: 654 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKEPTSTTCDKPAPTT 712
Query: 452 PSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLKDVRKRVK 511
P K + +PA TP P + P+ + K P+ K
Sbjct: 713 P-KGTAPTTPKEPAPTTPKEPAPTTP-KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPT 770
Query: 512 STYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESPP--NELSKERPADDPTASH 569
ST S P ++T + P + P E PP +E+S +PT H
Sbjct: 771 STTSDKP-APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 829
Query: 570 INPQKDPTADPSEPSADSYLTLSTAPTIAKAPFYVNGEAAERSSYENKEVEGELEMGPAG 629
+P + +EP+ + P + + ++ ++K E +L P
Sbjct: 830 KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPET 889
Query: 630 SSWCP 634
++ P
Sbjct: 890 TTAAP 894
Score = 38.1 bits (87), Expect = 0.061
Identities = 107/521 (20%), Positives = 157/521 (30%), Gaps = 73/521 (14%)
Query: 96 AATFQQLPKYVQGEEKYPKTSPPPTPVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTES 155
A T + P +E P T P P + P + + T K T +
Sbjct: 442 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 501
Query: 156 QRC-----ESRPTASKPPALKNPPKFAP-LPENSVNFCFDSAFLTVRRVPAEVSNTHQNS 209
+ E PT +K PA P + AP P+ T + PA +
Sbjct: 502 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT----- 556
Query: 210 YQPGRKHGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGTF 269
K + K P ++ T T E P+ KP P T
Sbjct: 557 -----KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT- 610
Query: 270 LHSENSAFESWNAHQPKLLERKDTAGTVPESKAPKHYGD--TTLLREPCP-PERTVSPCQ 326
+P ++ A T P++ AP + T +EP P + +P
Sbjct: 611 -----------TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 659
Query: 327 VQASCSQEENRLAAGALSTSIPWGCRDPGAQVFA-VEGKAPSSQPDSQEKPAQPPWRKPK 385
+ + A L P + P + A K P+S + P P P
Sbjct: 660 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT 719
Query: 386 TGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISK 445
T KE T +E T +G T P + A + P P S
Sbjct: 720 T---PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSD 775
Query: 446 LLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLKD 505
P P K + +PA TP P + P+ + +K P+ +
Sbjct: 776 KPAPTTP-KETAPTTPKEPAPTTPKKPAPTTP-ETPPPTTSEVSTPTTTKEPTTIH---- 829
Query: 506 VRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESP--PNELSKERPAD 563
KS S+P L EP P LE SP P + + PA
Sbjct: 830 -----KSPDESTPELSA-------------EPT------PKALENSPKEPGVPTTKTPAA 865
Query: 564 -----DPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAK 599
TA ++D P +A +T TA T K
Sbjct: 866 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK 906
Score = 38.1 bits (87), Expect = 0.061
Identities = 87/425 (20%), Positives = 134/425 (31%), Gaps = 53/425 (12%)
Query: 895 PRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAP 954
P P ++P P+ T + T P + S E + P
Sbjct: 465 PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 524
Query: 955 KGNFPSMPLVGEGDRVKAPPDAAPGLVA-SNCKSGSADSGKLAAPWH----IPTI----- 1004
K P+ P K P P A + K + + K AP PT
Sbjct: 525 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 584
Query: 1005 -ALPEG---DIEDQPPPWQPENCW----EEQTPGFKSHFL-STPRAGPPGRRLVPSERA- 1054
PE ++P P PE EE TP +TP+A P P+
Sbjct: 585 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 644
Query: 1055 --------NSPNPGSPGESSACSP---AASNIWEESSQAPGGP---ELLPEEPNQASPWA 1100
P P +P E++ +P A + + E + P P EL P + +
Sbjct: 645 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 704
Query: 1101 SSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELP 1160
PA T + +P E T +P+G+ PA T+ + P
Sbjct: 705 CDKPAPTTPKGTAPTT-----PKEPAPTTPKEPAPT-TPKGTAPTTLKEPAPTTPKKPAP 758
Query: 1161 AQLERTASKPPAVPPKTEKALRRAKKLA--SKRRKTDQAQEKHGESQEGKPCPEDLE--- 1215
+L T +K P + A K+ A + + +K + P P E
Sbjct: 759 KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 818
Query: 1216 -QTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPAYPATQ 1274
T + P + P + P + + P P E + PG P + TP P
Sbjct: 819 PTTTKEPTTIHKSPDESTPELSAEPTP-------KALENSPKEPGVPTTKTPAATKPEMT 871
Query: 1275 KVLQD 1279
+D
Sbjct: 872 TTAKD 876
Score = 37.4 bits (85), Expect = 0.10
Identities = 48/210 (22%), Positives = 71/210 (33%), Gaps = 15/210 (7%)
Query: 401 KTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHALDSA 460
K +T +GP L T P + A P EP P S TP P+ SA
Sbjct: 293 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT----PTTIKSAPTTPKEPAPTTTKSA 348
Query: 461 DSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLKD----VRKRVKSTYSS 516
+ P E P+ + KEP+ +++ + S K+ K+ T
Sbjct: 349 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 408
Query: 517 SPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESPPNELSKERPADDPTASHINPQKD- 575
P E T K+ + P +E P K P + P++
Sbjct: 409 EPAPTTPKEPT--PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 466
Query: 576 PTA----DPSEPSADSYLTLSTAPTIAKAP 601
PT P+ P + T +APT K P
Sbjct: 467 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 496
Score = 35.0 bits (79), Expect = 0.52
Identities = 64/281 (22%), Positives = 86/281 (30%), Gaps = 36/281 (12%)
Query: 1151 AGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQE-KHGESQEGKP 1209
A TS L P T +K PA+ E K+ AS K K + +P
Sbjct: 281 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 340
Query: 1210 CPEDLEQTQQRPLCPRE------------RPRHNFPVVRSLPPPVHRHSVSGF-SEPVGR 1256
P T+ P P+E P+ P P P S EP
Sbjct: 341 APTT---TKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 397
Query: 1257 RPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPSSE 1316
P P TP P T K +P P K P T + +
Sbjct: 398 TPKKPAPTTPKEPAPTTPK---EPT---------PTTPKEPA---PTTKEPAPTTPKEPA 442
Query: 1317 GASPEPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASAARARTQS 1376
+P+ P P P P +P P T P + + APT + P + A T +
Sbjct: 443 PTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 501
Query: 1377 VHESGLQLDPGPHGDCTPHSAGQRPHGP-PQSPGEEGVEAP 1416
+P P T A P P P +P + P
Sbjct: 502 KSAPTTPKEPSP--TTTKEPAPTTPKEPAPTTPKKPAPTTP 540
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 43.1 bits (100), Expect = 0.002
Identities = 72/323 (22%), Positives = 113/323 (34%), Gaps = 41/323 (12%)
Query: 893 ELPRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQP 952
E P P E+P AP +TP T K A ++P + E +
Sbjct: 654 EEPTPTTPEEP---APTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK---ETAPT 707
Query: 953 APKGNFPSMPLVGEGDRVK--APPDAAPGLV----ASNCKSGSADSGKLAAPWHIPTIAL 1006
PKG P+ K AP + AP ++ C + + K AP T
Sbjct: 708 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP---TTPKE 764
Query: 1007 PEGDIEDQPPPWQPENCWEEQTPGFKSHFLSTPRAGPPGRRLVP-------SERANSPNP 1059
P +P P P+ K +TP+ P + L P S ++ P P
Sbjct: 765 PAPTTPKEPAPTTPKGT---APTTLKEPAPTTPKKPAP-KELAPTTTKGPTSTTSDKPAP 820
Query: 1060 GSPGESSACSPAASNIWEESSQAPGGPELLPEEPNQAS-PWASSSPARVTRREDLTHALV 1118
+P E++ +P AP PE P ++ S P + P + + D
Sbjct: 821 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPD------ 874
Query: 1119 WEGGSDPLLELSAEDLRTL---SPRGSLLDVATSPAGTSGRLELPAQLERTASKPPAVPP 1175
+ ELSAE SP+ + +PA T + A+ + T P
Sbjct: 875 -----ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE 929
Query: 1176 KTEKALRRAKKLASKRRKTDQAQ 1198
T A + K+ A+ KT +++
Sbjct: 930 TTTAAPKMTKETATTTEKTTESK 952
Score = 38.5 bits (88), Expect = 0.047
Identities = 69/347 (19%), Positives = 111/347 (31%), Gaps = 23/347 (6%)
Query: 1025 EEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPG 1084
+E TP +TP+ P P P + E + +P AP
Sbjct: 364 KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT 423
Query: 1085 GPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLEL-SAEDLRTLSPRGSL 1143
+ P P + +P PA T +E + P + ++ +P+
Sbjct: 424 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 483
Query: 1144 LDVATSPAGTSGRLELPAQLER---TASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEK 1200
PA T+ + P + T +K P+ E A K + ++ K
Sbjct: 484 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 543
Query: 1201 HGESQEGKPCPEDLEQTQQRPLCPRE----RPRHNFPVVRSLPPPV--HRHSVSGFSEPV 1254
+ +P P + + P P+E P+ P P P + + +P
Sbjct: 544 SAPTTPKEPSPTTTK--EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 601
Query: 1255 GRRPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPS 1314
P P TP P T K L P + E P + P T + + + P
Sbjct: 602 PTTPKEPAPTTPKETAPTTPKKL-TPTTPEKLAPTTPEKPA------PTTPEELAPTTP- 653
Query: 1315 SEGASPEPPPPDALAAPYVLYPGF--QPVPVTALMPLRCSSQLSAPT 1359
E +P P A P P +P P T P + + APT
Sbjct: 654 -EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 699
Score = 38.1 bits (87), Expect = 0.061
Identities = 106/545 (19%), Positives = 168/545 (30%), Gaps = 51/545 (9%)
Query: 96 AATFQQLPKYVQGEEKYPKTSPPPTPVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTES 155
A T + P +E P T PTP + P + + P
Sbjct: 436 APTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK--------------- 480
Query: 156 QRCESRPTASKPPALKNPPKFAPLPENSVNFCFDSAFLTVRRVPAEVSNTHQNSYQPGRK 215
E PTA K PA P + AP + A T + E S T P
Sbjct: 481 ---EPAPTAPKKPAPTTPKEPAPTTPK------EPAPTTTK----EPSPTTPKEPAPTTT 527
Query: 216 HGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGTFLHSENS 275
++K P S+ P + T + P+ +P P + T
Sbjct: 528 KSAPTTTKEPAPTTTKSAPTTP-KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 586
Query: 276 AFESWNAHQPKLLERKDTAGTVPESKA---PKHYGDTTLLR-EPCPPERTVSPCQVQASC 331
+P K A T P+ A PK TT + P PE+ ++P +
Sbjct: 587 T----TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK-LAPTTPEKPA 641
Query: 332 SQEENRLAAGALSTSIPWGCRDPGAQVFAVEGKAPSSQPDSQEKPAQPPWRKPKTGKKGK 391
LA P +P ++ P++ ++PA P K K
Sbjct: 642 PTTPEELAPTTPEEPTPTTPEEPAPTT------PKAAAPNTPKEPA-PTTPKEPAPTTPK 694
Query: 392 ESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISKLLTPII 451
E T +E T +G T P + A + P +P P
Sbjct: 695 EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKEPTSTTCDKPAPTT 753
Query: 452 PSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLKDVRKRVK 511
P K + +PA TP P + P+ + K P+ K
Sbjct: 754 P-KGTAPTTPKEPAPTTPKEPAPTTP-KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPT 811
Query: 512 STYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESPP--NELSKERPADDPTASH 569
ST S P ++T + P + P E PP +E+S +PT H
Sbjct: 812 STTSDKP-APTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIH 870
Query: 570 INPQKDPTADPSEPSADSYLTLSTAPTIAKAPFYVNGEAAERSSYENKEVEGELEMGPAG 629
+P + +EP+ + P + + ++ ++K E +L P
Sbjct: 871 KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPET 930
Query: 630 SSWCP 634
++ P
Sbjct: 931 TTAAP 935
Score = 38.1 bits (87), Expect = 0.061
Identities = 107/521 (20%), Positives = 157/521 (30%), Gaps = 73/521 (14%)
Query: 96 AATFQQLPKYVQGEEKYPKTSPPPTPVQRRLEVPVSGLRSSNKPVSKVSTLIKSFDRTES 155
A T + P +E P T P P + P + + T K T +
Sbjct: 483 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 542
Query: 156 QRC-----ESRPTASKPPALKNPPKFAP-LPENSVNFCFDSAFLTVRRVPAEVSNTHQNS 209
+ E PT +K PA P + AP P+ T + PA +
Sbjct: 543 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT----- 597
Query: 210 YQPGRKHGEQESSKNPEMACHGSSSFLPAANDTATLCESKFPSPHHKPVTGEPGRGKGTF 269
K + K P ++ T T E P+ KP P T
Sbjct: 598 -----KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT- 651
Query: 270 LHSENSAFESWNAHQPKLLERKDTAGTVPESKAPKHYGD--TTLLREPCP-PERTVSPCQ 326
+P ++ A T P++ AP + T +EP P + +P
Sbjct: 652 -----------TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 700
Query: 327 VQASCSQEENRLAAGALSTSIPWGCRDPGAQVFA-VEGKAPSSQPDSQEKPAQPPWRKPK 385
+ + A L P + P + A K P+S + P P P
Sbjct: 701 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT 760
Query: 386 TGKKGKESLQDTLEEKTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISK 445
T KE T +E T +G T P + A + P P S
Sbjct: 761 T---PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSD 816
Query: 446 LLTPIIPSKHALDSADSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLKD 505
P P K + +PA TP P + P+ + +K P+ +
Sbjct: 817 KPAPTTP-KETAPTTPKEPAPTTPKKPAPTTP-ETPPPTTSEVSTPTTTKEPTTIH---- 870
Query: 506 VRKRVKSTYSSSPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESP--PNELSKERPAD 563
KS S+P L EP P LE SP P + + PA
Sbjct: 871 -----KSPDESTPELSA-------------EPT------PKALENSPKEPGVPTTKTPAA 906
Query: 564 -----DPTASHINPQKDPTADPSEPSADSYLTLSTAPTIAK 599
TA ++D P +A +T TA T K
Sbjct: 907 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK 947
Score = 38.1 bits (87), Expect = 0.061
Identities = 87/425 (20%), Positives = 134/425 (31%), Gaps = 53/425 (12%)
Query: 895 PRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAP 954
P P ++P P+ T + T P + S E + P
Sbjct: 506 PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 565
Query: 955 KGNFPSMPLVGEGDRVKAPPDAAPGLVA-SNCKSGSADSGKLAAPWH----IPTI----- 1004
K P+ P K P P A + K + + K AP PT
Sbjct: 566 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 625
Query: 1005 -ALPEG---DIEDQPPPWQPENCW----EEQTPGFKSHFL-STPRAGPPGRRLVPSERA- 1054
PE ++P P PE EE TP +TP+A P P+
Sbjct: 626 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTP 685
Query: 1055 --------NSPNPGSPGESSACSP---AASNIWEESSQAPGGP---ELLPEEPNQASPWA 1100
P P +P E++ +P A + + E + P P EL P + +
Sbjct: 686 KEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT 745
Query: 1101 SSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLLDVATSPAGTSGRLELP 1160
PA T + +P E T +P+G+ PA T+ + P
Sbjct: 746 CDKPAPTTPKGTAPTT-----PKEPAPTTPKEPAPT-TPKGTAPTTLKEPAPTTPKKPAP 799
Query: 1161 AQLERTASKPPAVPPKTEKALRRAKKLA--SKRRKTDQAQEKHGESQEGKPCPEDLE--- 1215
+L T +K P + A K+ A + + +K + P P E
Sbjct: 800 KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 859
Query: 1216 -QTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGGPQSLTPLPAYPATQ 1274
T + P + P + P + + P P E + PG P + TP P
Sbjct: 860 PTTTKEPTTIHKSPDESTPELSAEPTP-------KALENSPKEPGVPTTKTPAATKPEMT 912
Query: 1275 KVLQD 1279
+D
Sbjct: 913 TTAKD 917
Score = 37.4 bits (85), Expect = 0.10
Identities = 48/210 (22%), Positives = 71/210 (33%), Gaps = 15/210 (7%)
Query: 401 KTQTNQRGPPLYTKHNPQEQFSENNALDLPVEPNEHYDPPFNISKLLTPIIPSKHALDSA 460
K +T +GP L T P + A P EP P S TP P+ SA
Sbjct: 334 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT----PTTIKSAPTTPKEPAPTTTKSA 389
Query: 461 DSQPAERTPSPPGQLNGYQEKEPSECQSRDSYKSKAPSLLFNLKD----VRKRVKSTYSS 516
+ P E P+ + KEP+ +++ + S K+ K+ T
Sbjct: 390 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 449
Query: 517 SPLLKVLDEKTRGKVDGKQEPVSNGVILPNGLEESPPNELSKERPADDPTASHINPQKD- 575
P E T K+ + P +E P K P + P++
Sbjct: 450 EPAPTTPKEPT--PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 507
Query: 576 PTA----DPSEPSADSYLTLSTAPTIAKAP 601
PT P+ P + T +APT K P
Sbjct: 508 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 537
Score = 35.0 bits (79), Expect = 0.52
Identities = 64/281 (22%), Positives = 86/281 (30%), Gaps = 36/281 (12%)
Query: 1151 AGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQE-KHGESQEGKP 1209
A TS L P T +K PA+ E K+ AS K K + +P
Sbjct: 322 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 381
Query: 1210 CPEDLEQTQQRPLCPRE------------RPRHNFPVVRSLPPPVHRHSVSGF-SEPVGR 1256
P T+ P P+E P+ P P P S EP
Sbjct: 382 APTT---TKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 438
Query: 1257 RPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPSSE 1316
P P TP P T K +P P K P T + +
Sbjct: 439 TPKKPAPTTPKEPAPTTPK---EPT---------PTTPKEPA---PTTKEPAPTTPKEPA 483
Query: 1317 GASPEPPPPDALAAPYVLYPGFQPVPVTALMPLRCSSQLSAPTFLRQGPRASAARARTQS 1376
+P+ P P P P +P P T P + + APT + P + A T +
Sbjct: 484 PTAPKKPAPTTPKEPAPTTPK-EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 542
Query: 1377 VHESGLQLDPGPHGDCTPHSAGQRPHGP-PQSPGEEGVEAP 1416
+P P T A P P P +P + P
Sbjct: 543 KSAPTTPKEPSP--TTTKEPAPTTPKEPAPTTPKKPAPTTP 581
>gi|148806908 fibronectin type III domain containing 1 [Homo sapiens]
Length = 1894
Score = 43.1 bits (100), Expect = 0.002
Identities = 66/277 (23%), Positives = 96/277 (34%), Gaps = 32/277 (11%)
Query: 1146 VATSPAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGESQ 1205
V SP G + + +L L+ P K + ++A++L + T+ E+ S+
Sbjct: 493 VPASPQGRNAK-DLLLDLKNKILANGGAPRKPQLRAKKAEEL--DLQSTEITGEEELGSR 549
Query: 1206 EGKPCPEDLEQTQQRPLCPRERPRHNF-----PVVRSLPPPVHRHS---VSGFSEPVGRR 1257
E P Q Q+R L P R H+ VR+ P + R GFS R
Sbjct: 550 EDSPMSPSDTQDQKRTLRPPSRHGHSVVAPGRTAVRARMPALPRREGVDKPGFSLATQPR 609
Query: 1258 PGGPQSLTPLPAYPA-TQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSI-PSS 1315
PG P S + PA+ A TQ P LP + D + + S+ P
Sbjct: 610 PGAPPSASASPAHHASTQGTSHRP--------SLPASLNDNDLVDSDEDERAVGSLHPKG 661
Query: 1316 EGASPEP-------PPPDALAAPYVLYPGFQPVPVTALMP----LRCSSQLSAPTFLRQG 1364
A P P P L ++PG +P P S SAP
Sbjct: 662 AFAQPRPALSPSRQSPSSVLRDRSSVHPGAKPASPARRTPHSGAAEEDSSASAPPSRLSP 721
Query: 1365 PRASAARARTQSVHESGLQLDPGPHGDCTPHSAGQRP 1401
P ++R H S G G+ P + P
Sbjct: 722 PHGGSSRLLPTQPHLSSPLSKGGKDGEDAPATNSNAP 758
Score = 31.2 bits (69), Expect = 7.5
Identities = 78/399 (19%), Positives = 135/399 (33%), Gaps = 73/399 (18%)
Query: 888 GHKEEELPRPEWGEDPGFCAPENQDILGTSTPTNTRGTRVKCMANEVMEDPGQGSSMARM 947
G +E+E P P N + +S +RG ++ P +G+S+ R
Sbjct: 877 GDEEDEKPLP--------ATVVNDHVPSSSRQPISRGWE------DLRRSPQRGASLHRK 922
Query: 948 E---------ASQPAPKGNFPSMPLVGE-------GDRVKAPPDAAPGLVASNCKSGSAD 991
E + P+G + S+ + D P A PG +
Sbjct: 923 EPIPENPKSTGADTHPQGKYSSLASKAQDVQQSTDADTEGHSPKAQPGSTDRHASPARPP 982
Query: 992 SGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFKSHF---------LSTPRAG 1042
+ + +P P + QPPP + PG +S LS +AG
Sbjct: 983 AARSQQHPSVPRRMTPGRAPQQQPPP---PVATSQHHPGPQSRDAGRSPSQPRLSLTQAG 1039
Query: 1043 PPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPGGPELLPEEPNQASPWASS 1102
P P+ + S + P +S+ + + + A G + ++ +
Sbjct: 1040 RPR----PTSQGRSHSSSDPYTASSRGMLPTALQNQDEDAQGSYD---DDSTEVEAQDVR 1092
Query: 1103 SPARVTRREDLTHALV-WEGGSDPLLELSAEDLRTLSPRGSLLDVA--TSPAGTSGRLEL 1159
+PA R ++ +L + P + D R S RG A + P G R +
Sbjct: 1093 APAHAARAKEAAASLPKHQQVESPTGAGAGGDHR--SQRGHAASPARPSRPGGPQSRARV 1150
Query: 1160 PAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEKHGES--------------- 1204
P++ S+PP+ P + K+ + A + D K G+
Sbjct: 1151 PSRAAPGKSEPPSKRPLSSKSQQSVS--AEDDEEEDAGFFKGGKEDLLSSSVPKWPSSST 1208
Query: 1205 -QEGKPCPEDLEQTQQRP-LCPRERPRHNFPVVRSLPPP 1241
+ GK L + ++ P + R PV R LPPP
Sbjct: 1209 PRGGKDADGSLAKEEREPAIALAPRGGSLAPVKRPLPPP 1247
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 43.1 bits (100), Expect = 0.002
Identities = 90/436 (20%), Positives = 137/436 (31%), Gaps = 65/436 (14%)
Query: 1025 EEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPG 1084
EE P + P PP PS P P + C P + +P
Sbjct: 388 EEMMPAAEKEEAKLPP--PPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPP 445
Query: 1085 GPELLPEEPNQASPWASSSPARVTRREDLTHALVWEGGSDPLLELSAEDLRTLSPRGSLL 1144
P E+ P ++ +R R LT + + + + P G+
Sbjct: 446 PPPAQEEQEESPPPVVPATCSRKRGRPPLTPS-----------QRAEREAARAGPEGTSP 494
Query: 1145 DVATSPAGTSGRLELPAQLERTASKPPAVPPKTEKALRRAKK-----LASKRRKTDQAQE 1199
T T G E P V PK+ L+ ++ ++++ + +
Sbjct: 495 PTPTPSTATGGPPE----------DSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPR 544
Query: 1200 KHGESQEGKPCPEDLEQTQQRPL-----CPRE------RPRHNFPVVRSLPPPVHRHSVS 1248
+ + KP ++ + P+ P+E PR P +P P R S+
Sbjct: 545 RFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSI- 603
Query: 1249 GFSEPVGRRPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGK-- 1306
EP R + L P P P P PL ++ F E
Sbjct: 604 -LREPTFRWTSLTRELPPPPPAPPPPPA-PSPPPAPATSSRRPLLLRAPQFTPSEAHLKI 661
Query: 1307 YVKVSIPSSEGA--SPEPPPPDALAAP------------YVLYPGFQPVPVTALMPLRCS 1352
Y V P GA +PEP PP A +P ++ P F PV T P++
Sbjct: 662 YESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTT---PVKAE 718
Query: 1353 SQLSAPTFLRQGPRASAARARTQSVHESGLQLDPGPHGDCTPHSAGQRPHGPPQSPGEEG 1412
L GP+ A + LQ P P Q P P Q P E
Sbjct: 719 VSPHGAPALSNGPQTQAQLLQPL----QALQTQLLPQALPPPQPQLQPPPSPQQMPPLEK 774
Query: 1413 VEAPGLGIISTDDLED 1428
G+G + +E+
Sbjct: 775 ARIAGVGSLPLSGVEE 790
Score = 32.7 bits (73), Expect = 2.6
Identities = 38/162 (23%), Positives = 61/162 (37%), Gaps = 3/162 (1%)
Query: 1190 KRRKTDQAQEKHGESQEGKPCPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSG 1249
+ +K ++ ++K GE +E + E++ ++ P P S PPP+ S S
Sbjct: 366 EEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLT-PPAPSPPPPLPPPSTSP 424
Query: 1250 FSEPVGRRPGGPQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVK 1309
P+ P P S PLP+ P + +S V + + + P +
Sbjct: 425 -PPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAERE 483
Query: 1310 VSIPSSEGASPEPPPPD-ALAAPYVLYPGFQPVPVTALMPLR 1350
+ EG SP P P A P P P T L +R
Sbjct: 484 AARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIR 525
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.128 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 72,614,078
Number of Sequences: 37866
Number of extensions: 4372340
Number of successful extensions: 20307
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 670
Number of HSP's that attempted gapping in prelim test: 17111
Number of HSP's gapped (non-prelim): 3925
length of query: 1435
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1320
effective length of database: 13,892,928
effective search space: 18338664960
effective search space used: 18338664960
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.