BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|205360947 microtubule associated monoxygenase, calponin and LIM domain containing 1 isoform 1 [Homo sapiens] (1067 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|205360947 microtubule associated monoxygenase, calponin and L... 2152 0.0 gi|226530313 microtubule associated monoxygenase, calponin and L... 1353 0.0 gi|209862789 microtubule associated monoxygenase, calponin and L... 730 0.0 gi|170172518 microtubule associated monoxygenase, calponin and L... 726 0.0 gi|209862793 microtubule associated monoxygenase, calponin and L... 687 0.0 gi|7662284 microtubule associated monoxygenase, calponin and LIM... 629 e-180 gi|31324577 molecule interacting with Rab13 [Homo sapiens] 138 2e-32 gi|33667117 MICAL-like 2 isoform 1 [Homo sapiens] 130 7e-30 gi|118918413 MICAL C-terminal like [Homo sapiens] 119 2e-26 gi|67782321 spectrin beta isoform a [Homo sapiens] 77 1e-13 gi|67782319 spectrin beta isoform b [Homo sapiens] 77 1e-13 gi|170016061 spectrin, beta, non-erythrocytic 5 [Homo sapiens] 74 6e-13 gi|150378549 tangerin [Homo sapiens] 74 1e-12 gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens] 72 2e-12 gi|4557241 actinin, alpha 3 [Homo sapiens] 71 5e-12 gi|4501893 actinin, alpha 2 [Homo sapiens] 71 5e-12 gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [... 70 1e-11 gi|194097352 actinin, alpha 1 isoform c [Homo sapiens] 69 2e-11 gi|194097350 actinin, alpha 1 isoform a [Homo sapiens] 69 2e-11 gi|4501891 actinin, alpha 1 isoform b [Homo sapiens] 69 2e-11 gi|33188445 microfilament and actin filament cross-linker protei... 68 4e-11 gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo ... 67 7e-11 gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo ... 67 7e-11 gi|12025678 actinin, alpha 4 [Homo sapiens] 67 1e-10 gi|118918407 spectrin repeat containing, nuclear envelope 2 isof... 66 2e-10 gi|118918403 spectrin repeat containing, nuclear envelope 2 isof... 66 2e-10 gi|116517305 cysteine-rich protein 3 [Homo sapiens] 62 2e-09 gi|224451082 cytospin A [Homo sapiens] 60 1e-08 gi|224451080 cytospin A [Homo sapiens] 60 1e-08 gi|169218211 PREDICTED: similar to plectin 1, partial [Homo sapi... 60 1e-08 >gi|205360947 microtubule associated monoxygenase, calponin and LIM domain containing 1 isoform 1 [Homo sapiens] Length = 1067 Score = 2152 bits (5575), Expect = 0.0 Identities = 1067/1067 (100%), Positives = 1067/1067 (100%) Query: 1 MASPTSTNPAHAHFESFLQAQLCQDVLSSFQELCGALGLEPGGGLPQYHKIKDQLNYWSA 60 MASPTSTNPAHAHFESFLQAQLCQDVLSSFQELCGALGLEPGGGLPQYHKIKDQLNYWSA Sbjct: 1 MASPTSTNPAHAHFESFLQAQLCQDVLSSFQELCGALGLEPGGGLPQYHKIKDQLNYWSA 60 Query: 61 KSLWTKLDKRAGQPVYQQGRACTSTKCLVVGAGPCGLRVAVELALLGARVVLVEKRTKFS 120 KSLWTKLDKRAGQPVYQQGRACTSTKCLVVGAGPCGLRVAVELALLGARVVLVEKRTKFS Sbjct: 61 KSLWTKLDKRAGQPVYQQGRACTSTKCLVVGAGPCGLRVAVELALLGARVVLVEKRTKFS 120 Query: 121 RHNVLHLWPFTIHDLRALGAKKFYGRFCTGTLDHISIRQLQLLLLKVALLLGVEIHWGVT 180 RHNVLHLWPFTIHDLRALGAKKFYGRFCTGTLDHISIRQLQLLLLKVALLLGVEIHWGVT Sbjct: 121 RHNVLHLWPFTIHDLRALGAKKFYGRFCTGTLDHISIRQLQLLLLKVALLLGVEIHWGVT 180 Query: 181 FTGLQPPPRKGSGWRAQLQPNPPAQLANYEFDVLISAAGGKFVPEGFKVREMRGKLAIGI 240 FTGLQPPPRKGSGWRAQLQPNPPAQLANYEFDVLISAAGGKFVPEGFKVREMRGKLAIGI Sbjct: 181 FTGLQPPPRKGSGWRAQLQPNPPAQLANYEFDVLISAAGGKFVPEGFKVREMRGKLAIGI 240 Query: 241 TANFVNGRTVEETQVPEISGVARIYNQSFFQSLLKATGIDLENIVYYKDDTHYFVMTAKK 300 TANFVNGRTVEETQVPEISGVARIYNQSFFQSLLKATGIDLENIVYYKDDTHYFVMTAKK Sbjct: 241 TANFVNGRTVEETQVPEISGVARIYNQSFFQSLLKATGIDLENIVYYKDDTHYFVMTAKK 300 Query: 301 QCLLRLGVLRQDWPDTNRLLGSANVVPEALQRFTRAAADFATHGKLGKLEFAQDAHGQPD 360 QCLLRLGVLRQDWPDTNRLLGSANVVPEALQRFTRAAADFATHGKLGKLEFAQDAHGQPD Sbjct: 301 QCLLRLGVLRQDWPDTNRLLGSANVVPEALQRFTRAAADFATHGKLGKLEFAQDAHGQPD 360 Query: 361 VSAFDFTSMMRAESSARVQEKHGARLLLGLVGDCLVEPFWPLGTGVARGFLAAFDAAWMV 420 VSAFDFTSMMRAESSARVQEKHGARLLLGLVGDCLVEPFWPLGTGVARGFLAAFDAAWMV Sbjct: 361 VSAFDFTSMMRAESSARVQEKHGARLLLGLVGDCLVEPFWPLGTGVARGFLAAFDAAWMV 420 Query: 421 KRWAEGAESLEVLAERESLYQLLSQTSPENMHRNVAQYGLDPATRYPNLNLRAVTPNQVR 480 KRWAEGAESLEVLAERESLYQLLSQTSPENMHRNVAQYGLDPATRYPNLNLRAVTPNQVR Sbjct: 421 KRWAEGAESLEVLAERESLYQLLSQTSPENMHRNVAQYGLDPATRYPNLNLRAVTPNQVR 480 Query: 481 DLYDVLAKEPVQRNNDKTDTGMPATGSAGTQEELLRWCQEQTAGYPGVHVSDLSSSWADG 540 DLYDVLAKEPVQRNNDKTDTGMPATGSAGTQEELLRWCQEQTAGYPGVHVSDLSSSWADG Sbjct: 481 DLYDVLAKEPVQRNNDKTDTGMPATGSAGTQEELLRWCQEQTAGYPGVHVSDLSSSWADG 540 Query: 541 LALCALVYRLQPGLLEPSELQGLGALEATAWALKVAENELGITPVVSAQAVVAGSDPLGL 600 LALCALVYRLQPGLLEPSELQGLGALEATAWALKVAENELGITPVVSAQAVVAGSDPLGL Sbjct: 541 LALCALVYRLQPGLLEPSELQGLGALEATAWALKVAENELGITPVVSAQAVVAGSDPLGL 600 Query: 601 IAYLSHFHSAFKSMAHSPGPVSQASPGTSSAVLFLSKLQRTLQRSRAKENAEDAGGKKLR 660 IAYLSHFHSAFKSMAHSPGPVSQASPGTSSAVLFLSKLQRTLQRSRAKENAEDAGGKKLR Sbjct: 601 IAYLSHFHSAFKSMAHSPGPVSQASPGTSSAVLFLSKLQRTLQRSRAKENAEDAGGKKLR 660 Query: 661 LEMEAETPSTEVPPDPEPGVPLTPPSQHQEAGAGDLCALCGEHLYVLERLCVNGHFFHRS 720 LEMEAETPSTEVPPDPEPGVPLTPPSQHQEAGAGDLCALCGEHLYVLERLCVNGHFFHRS Sbjct: 661 LEMEAETPSTEVPPDPEPGVPLTPPSQHQEAGAGDLCALCGEHLYVLERLCVNGHFFHRS 720 Query: 721 CFRCHTCEATLWPGGYEQHPGDGHFYCLQHLPQTDHKAEGSDRGPESPELPTPSENSMPP 780 CFRCHTCEATLWPGGYEQHPGDGHFYCLQHLPQTDHKAEGSDRGPESPELPTPSENSMPP Sbjct: 721 CFRCHTCEATLWPGGYEQHPGDGHFYCLQHLPQTDHKAEGSDRGPESPELPTPSENSMPP 780 Query: 781 GLSTPTASQEGAGPVPDPSQPTRRQIRLSSPERQRLSSLNLTPDPEMEPPPKPPRSCSAL 840 GLSTPTASQEGAGPVPDPSQPTRRQIRLSSPERQRLSSLNLTPDPEMEPPPKPPRSCSAL Sbjct: 781 GLSTPTASQEGAGPVPDPSQPTRRQIRLSSPERQRLSSLNLTPDPEMEPPPKPPRSCSAL 840 Query: 841 ARHALESSFVGWGLPVQSPQALVAMEKEEKESPFSSEEEEEDVPLDSDVEQALQTFAKTS 900 ARHALESSFVGWGLPVQSPQALVAMEKEEKESPFSSEEEEEDVPLDSDVEQALQTFAKTS Sbjct: 841 ARHALESSFVGWGLPVQSPQALVAMEKEEKESPFSSEEEEEDVPLDSDVEQALQTFAKTS 900 Query: 901 GTMNNYPTWRRTLLRRAKEEEMKRFCKAQTIQRRLNEIEAALRELEAEGVKLELALRRQS 960 GTMNNYPTWRRTLLRRAKEEEMKRFCKAQTIQRRLNEIEAALRELEAEGVKLELALRRQS Sbjct: 901 GTMNNYPTWRRTLLRRAKEEEMKRFCKAQTIQRRLNEIEAALRELEAEGVKLELALRRQS 960 Query: 961 SSPEQQKKLWVGQLLQLVDKKNSLVAEEAELMITVQELNLEEKQWQLDQELRGYMNREEN 1020 SSPEQQKKLWVGQLLQLVDKKNSLVAEEAELMITVQELNLEEKQWQLDQELRGYMNREEN Sbjct: 961 SSPEQQKKLWVGQLLQLVDKKNSLVAEEAELMITVQELNLEEKQWQLDQELRGYMNREEN 1020 Query: 1021 LKTAADRQAEDQVLRKLVDLVNQRDALIRFQEERRLSELALGTGAQG 1067 LKTAADRQAEDQVLRKLVDLVNQRDALIRFQEERRLSELALGTGAQG Sbjct: 1021 LKTAADRQAEDQVLRKLVDLVNQRDALIRFQEERRLSELALGTGAQG 1067 >gi|226530313 microtubule associated monoxygenase, calponin and LIM domain containing 1 isoform 2 [Homo sapiens] Length = 981 Score = 1353 bits (3502), Expect = 0.0 Identities = 671/673 (99%), Positives = 672/673 (99%) Query: 395 LVEPFWPLGTGVARGFLAAFDAAWMVKRWAEGAESLEVLAERESLYQLLSQTSPENMHRN 454 L +PFWPLGTGVARGFLAAFDAAWMVKRWAEGAESLEVLAERESLYQLLSQTSPENMHRN Sbjct: 309 LRQPFWPLGTGVARGFLAAFDAAWMVKRWAEGAESLEVLAERESLYQLLSQTSPENMHRN 368 Query: 455 VAQYGLDPATRYPNLNLRAVTPNQVRDLYDVLAKEPVQRNNDKTDTGMPATGSAGTQEEL 514 VAQYGLDPATRYPNLNLRAVTPNQVRDLYDVLAKEPVQRNNDKTDTGMPATGSAGTQEEL Sbjct: 369 VAQYGLDPATRYPNLNLRAVTPNQVRDLYDVLAKEPVQRNNDKTDTGMPATGSAGTQEEL 428 Query: 515 LRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATAWALK 574 LRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATAWALK Sbjct: 429 LRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATAWALK 488 Query: 575 VAENELGITPVVSAQAVVAGSDPLGLIAYLSHFHSAFKSMAHSPGPVSQASPGTSSAVLF 634 VAENELGITPVVSAQAVVAGSDPLGLIAYLSHFHSAFKSMAHSPGPVSQASPGTSSAVLF Sbjct: 489 VAENELGITPVVSAQAVVAGSDPLGLIAYLSHFHSAFKSMAHSPGPVSQASPGTSSAVLF 548 Query: 635 LSKLQRTLQRSRAKENAEDAGGKKLRLEMEAETPSTEVPPDPEPGVPLTPPSQHQEAGAG 694 LSKLQRTLQRSRAKENAEDAGGKKLRLEMEAETPSTEVPPDPEPGVPLTPPSQHQEAGAG Sbjct: 549 LSKLQRTLQRSRAKENAEDAGGKKLRLEMEAETPSTEVPPDPEPGVPLTPPSQHQEAGAG 608 Query: 695 DLCALCGEHLYVLERLCVNGHFFHRSCFRCHTCEATLWPGGYEQHPGDGHFYCLQHLPQT 754 DLCALCGEHLYVLERLCVNGHFFHRSCFRCHTCEATLWPGGYEQHPGDGHFYCLQHLPQT Sbjct: 609 DLCALCGEHLYVLERLCVNGHFFHRSCFRCHTCEATLWPGGYEQHPGDGHFYCLQHLPQT 668 Query: 755 DHKAEGSDRGPESPELPTPSENSMPPGLSTPTASQEGAGPVPDPSQPTRRQIRLSSPERQ 814 DHKAEGSDRGPESPELPTPSENSMPPGLSTPTASQEGAGPVPDPSQPTRRQIRLSSPERQ Sbjct: 669 DHKAEGSDRGPESPELPTPSENSMPPGLSTPTASQEGAGPVPDPSQPTRRQIRLSSPERQ 728 Query: 815 RLSSLNLTPDPEMEPPPKPPRSCSALARHALESSFVGWGLPVQSPQALVAMEKEEKESPF 874 RLSSLNLTPDPEMEPPPKPPRSCSALARHALESSFVGWGLPVQSPQALVAMEKEEKESPF Sbjct: 729 RLSSLNLTPDPEMEPPPKPPRSCSALARHALESSFVGWGLPVQSPQALVAMEKEEKESPF 788 Query: 875 SSEEEEEDVPLDSDVEQALQTFAKTSGTMNNYPTWRRTLLRRAKEEEMKRFCKAQTIQRR 934 SSEEEEEDVPLDSDVEQALQTFAKTSGTMNNYPTWRRTLLRRAKEEEMKRFCKAQTIQRR Sbjct: 789 SSEEEEEDVPLDSDVEQALQTFAKTSGTMNNYPTWRRTLLRRAKEEEMKRFCKAQTIQRR 848 Query: 935 LNEIEAALRELEAEGVKLELALRRQSSSPEQQKKLWVGQLLQLVDKKNSLVAEEAELMIT 994 LNEIEAALRELEAEGVKLELALRRQSSSPEQQKKLWVGQLLQLVDKKNSLVAEEAELMIT Sbjct: 849 LNEIEAALRELEAEGVKLELALRRQSSSPEQQKKLWVGQLLQLVDKKNSLVAEEAELMIT 908 Query: 995 VQELNLEEKQWQLDQELRGYMNREENLKTAADRQAEDQVLRKLVDLVNQRDALIRFQEER 1054 VQELNLEEKQWQLDQELRGYMNREENLKTAADRQAEDQVLRKLVDLVNQRDALIRFQEER Sbjct: 909 VQELNLEEKQWQLDQELRGYMNREENLKTAADRQAEDQVLRKLVDLVNQRDALIRFQEER 968 Query: 1055 RLSELALGTGAQG 1067 RLSELALGTGAQG Sbjct: 969 RLSELALGTGAQG 981 Score = 635 bits (1638), Expect = 0.0 Identities = 313/315 (99%), Positives = 313/315 (99%), Gaps = 1/315 (0%) Query: 1 MASPTSTNPAHAHFESFLQAQLCQDVLSSFQELCGALGLEPGGGLPQYHKIKDQLNYWSA 60 MASPTSTNPAHAHFESFLQAQLCQDVLSSFQELCGALGLEPGGGLPQYHKIKDQLNYWSA Sbjct: 1 MASPTSTNPAHAHFESFLQAQLCQDVLSSFQELCGALGLEPGGGLPQYHKIKDQLNYWSA 60 Query: 61 KSLWTKLDKRAGQPVYQQGRACTSTKCLVVGAGPCGLRVAVELALLGARVVLVEKRTKFS 120 KSLWTKLDKRAGQPVYQQGRACTSTKCLVVGAGPCGLRVAVELALLGARVVLVEKRTKFS Sbjct: 61 KSLWTKLDKRAGQPVYQQGRACTSTKCLVVGAGPCGLRVAVELALLGARVVLVEKRTKFS 120 Query: 121 RHNVLHLWPFTIHDLRALGAKKFYGRFCTGTLDHISIRQLQLLLLKVALLLGVEIHWGVT 180 RHNVLHLWPFTIHDLRALGAKKFYGRFCTGTLDHISIRQLQLLLLKVALLLGVEIHWGVT Sbjct: 121 RHNVLHLWPFTIHDLRALGAKKFYGRFCTGTLDHISIRQLQLLLLKVALLLGVEIHWGVT 180 Query: 181 FTGLQPPPRKGSGWRAQLQPNPPAQLANYEFDVLISAAGGKFVPEGFKVREMRGKLAIGI 240 FTGLQPPPRKGSGWRAQLQPNPPAQLANYEFDVLISAAGGKFVPEGFKVREMRGKLAIGI Sbjct: 181 FTGLQPPPRKGSGWRAQLQPNPPAQLANYEFDVLISAAGGKFVPEGFKVREMRGKLAIGI 240 Query: 241 TANFVNGRTVEETQVPEISGVARIYNQSFFQSLLKATGIDLENIVYYKDDTHYFVMTAKK 300 TANFVNGRTVEETQVPEISGVARIYNQSFFQSLLKATGIDLENIVYYKDDTHYFVMTAKK Sbjct: 241 TANFVNGRTVEETQVPEISGVARIYNQSFFQSLLKATGIDLENIVYYKDDTHYFVMTAKK 300 Query: 301 QCLLRLGVLRQD-WP 314 QCLLRLGVLRQ WP Sbjct: 301 QCLLRLGVLRQPFWP 315 >gi|209862789 microtubule associated monoxygenase, calponin and LIM domain containing 3 isoform 1 [Homo sapiens] Length = 2002 Score = 730 bits (1885), Expect = 0.0 Identities = 419/954 (43%), Positives = 550/954 (57%), Gaps = 92/954 (9%) Query: 8 NPAHAHFESFLQAQLCQDVLSSFQELCGALGLEPGGGLPQYHKIKDQLNYWSAKSLWTKL 67 NPAH F+ F+QA C+ L +FQELC L L+P YHK+K +LNYW AK+LW KL Sbjct: 10 NPAHVLFDRFVQATTCKGTLKAFQELCDHLELKPKDYRSFYHKLKSKLNYWKAKALWAKL 69 Query: 68 DKRAGQPVYQQGRACTSTKCLVVGAGPCGLRVAVELALLGARVVLVEKRTKFSRHNVLHL 127 DKR Y++G+ACT+TKCL++GAGPCGLR A++L+LLGA+VV++EKR FSR+NVLHL Sbjct: 70 DKRGSHKDYKKGKACTNTKCLIIGAGPCGLRTAIDLSLLGAKVVVIEKRDAFSRNNVLHL 129 Query: 128 WPFTIHDLRALGAKKFYGRFCTGTLDHISIRQLQLLLLKVALLLGVEIHWGVTFTGLQPP 187 WPFTIHDLR LGAKKFYG+FC G +DHISIRQLQL+LLKVAL+LG+EIH V F GL P Sbjct: 130 WPFTIHDLRGLGAKKFYGKFCAGAIDHISIRQLQLILLKVALILGIEIHVNVEFQGLIQP 189 Query: 188 PRKGS----GWRAQLQPNPPAQLANYEFDVLISAAGGKFVPEGFKVREMRGKLAIGITAN 243 P GWRA + P ++ YEF+V+I G + EGF+ +E RGKLAI ITAN Sbjct: 190 PEDQENERIGWRALVHPKTHP-VSEYEFEVIIGGDGRRNTLEGFRRKEFRGKLAIAITAN 248 Query: 244 FVNGRTVEETQVPEISGVARIYNQSFFQSLLKATGIDLENIVYYKDDTHYFVMTAKKQCL 303 F+N T E +V EISGVA I+NQ FFQ L +ATGIDLENIVYYKDDTHYFVMTAKKQ L Sbjct: 249 FINRNTTAEAKVEEISGVAFIFNQKFFQELREATGIDLENIVYYKDDTHYFVMTAKKQSL 308 Query: 304 LRLGVLRQDWPDTNRLLGSANVVPEALQRFTRAAADFATHGKLGKLEFAQDAHGQPDVSA 363 L GV+ D+ DT LL NV EAL + R AADF+T +L L+FA + +GQPDV+ Sbjct: 309 LDKGVILHDYADTELLLSRENVDQEALLSYAREAADFSTQQQLPSLDFAINHYGQPDVAM 368 Query: 364 FDFTSMMRAESSARVQEKHGARLLLGLVGDCLVEPFWPLGTGVARGFLAAFDAAWMVKRW 423 FDFT M +E++A V+E++G +LL+ LVGD L+EPFWP+GTG+ARGFLAA D+AWMV+ W Sbjct: 369 FDFTCMYASENAALVREQNGHQLLVALVGDSLLEPFWPMGTGIARGFLAAMDSAWMVRSW 428 Query: 424 AEGAESLEVLAERESLYQLLSQTSPENMHRNVAQYGLDPATRYPNLNLRAVTPNQVRDLY 483 + G LEVLAERES+Y+LL QT+PEN+ +N +QY +DP TRYPN+N+ + P+QVR LY Sbjct: 429 SLGTSPLEVLAERESIYRLLPQTTPENVSKNFSQYSIDPVTRYPNINVNFLRPSQVRHLY 488 Query: 484 DVLAKEPVQRN-----NDKTDTGMPATGSAGTQEELLRWCQEQTAGYPGVHVSDLSSSWA 538 D + + N +T + S +LL WCQ QT GY GV+V+DL+ SW Sbjct: 489 DTGETKDIHLEMESLVNSRTTPKLTRNESVARSSKLLGWCQRQTDGYAGVNVTDLTMSWK 548 Query: 539 DGLALCALVYRLQPGLLEPSELQGLGALEATAWALKVAENELGITPVVSAQ--AVVAGSD 596 GLALCA+++R +P L++ L + A +AE ELGI+P+++ + A V D Sbjct: 549 SGLALCAIIHRYRPDLIDFDSLDEQNVEKNNQLAFDIAEKELGISPIMTGKEMASVGEPD 608 Query: 597 PLGLIAYLSHFHSAFKSMAHSPGPVSQAS-------PGTSSAVLFLSKLQRTLQRSRA-- 647 L ++ YL+ F+ FK S + + T S + FLSKL +T+ R R+ Sbjct: 609 KLSMVMYLTQFYEMFKDSLPSSDTLDLNAEEKAVLIASTRSPISFLSKLGQTISRKRSPK 668 Query: 648 --KENAEDAGGKKLRLEMEAETPSTEVPPDPEPGVPLT---------------------- 683 KE D GK+ + E + P + T Sbjct: 669 DKKEKDLDGAGKRRKTSQSEEEEAPRGHRGERPTLVSTLTDRRMDVAVGNQNKVKYMATQ 728 Query: 684 --------PPSQH--------------QEAGAGDLCALCGEHLYVLERLCVNGHFFHRSC 721 P+Q Q G D C C + +YV+ERL G FFHRSC Sbjct: 729 LLAKFEENAPAQSIGIRRQGSMKKEFPQNLGGSDTCYFCQKRVYVMERLSAEGKFFHRSC 788 Query: 722 FRCHTCEATLWPGGYEQHPGDGHFYCLQH-------LPQTDHKAEGSDRGPES----PEL 770 F+C C TL Y DG FYC H Q A G E+ + Sbjct: 789 FKCEYCATTLRLSAYAYDIEDGKFYCKPHYCYRLSGYAQRKRPAVAPLSGKEAKGPLQDG 848 Query: 771 PTPSENSMPPGLSTPTASQEGAGPVPDPSQPTRRQIRLSSPERQRLSS--LNLTPDPEME 828 T N +++ T G+G V +P+ + +PER L + L+L ++ Sbjct: 849 ATTDANGRANAVASSTERTPGSG-VNGLEEPSIAKRLRGTPERIELENYRLSLRQAEALQ 907 Query: 829 PPPKPPRSCSALARHALESSFVGWGLPVQSPQALVAMEKEEKESPFSSEEEEED 882 P+ + A H L SS + G + VA E E EEEEE+ Sbjct: 908 EVPEETQ-----AEHNL-SSVLDTG-----AEEDVASSSSESEMEEEGEEEEEE 950 Score = 125 bits (314), Expect = 2e-28 Identities = 104/346 (30%), Positives = 166/346 (47%), Gaps = 49/346 (14%) Query: 758 AEGSDRGPESPELPTPSENSMPPGLSTPTASQEGAGPVPDPSQP-------------TRR 804 ++G +R P+SP PT S P L S+E P D P +++ Sbjct: 1640 SQGKERRPDSPTRPT-LRGSEEPTLKHEATSEEVLSPPSDSGGPDGSFTSSEGSSGKSKK 1698 Query: 805 QIRLSSPERQRLSSLNLTPDPEMEPPPKPPRS----CSALARHALESSFVGW-------- 852 + L SP R + + E PP KP + +A + +S F G+ Sbjct: 1699 RSSLFSPRRNKKEKKS---KGEGRPPEKPSSNLLEEAAAKPKSLWKSVFSGYKKDKKKKA 1755 Query: 853 -----------GLPVQSPQ--ALVAMEKEEKESPFSSEEEEEDVPLDSDVEQALQTFAK- 898 G V S + L + E + S E+ D+ D +E++ Q + Sbjct: 1756 DDKSCPSTPSSGATVDSGKHRVLPVVRAELQLRRQLSFSEDSDLSSDDVLEKSSQKSRRE 1815 Query: 899 ----TSGTMNNYPTWR--RTLLRRAKEEEMKRFCKAQTIQRRLNEIEAALRELEAEGVKL 952 T +N T R + R+AK+EE+KR +AQ IQR+L ++E R LE GV + Sbjct: 1816 PRTYTEEELNAKLTRRVQKAARRQAKQEELKRLHRAQIIQRQLQQVEERQRRLEERGVAV 1875 Query: 953 ELALRRQSSSPEQQKKLWVGQLLQLVDKKNSLVAEEAELMITVQELNLEEKQWQLDQELR 1012 E ALR ++ ++ + + +LV +KN++V E+ELMI +EL LE++Q +L QELR Sbjct: 1876 EKALRGEAGMGKKDDPKLMQEWFKLVQEKNAMVRYESELMIFARELELEDRQSRLQQELR 1935 Query: 1013 GYMNREENLKTAADRQAEDQVLRKLVDLVNQRDALIRFQEERRLSE 1058 M E++LKT + E Q+L +++++V QRD+L+ EE+RL E Sbjct: 1936 ERMAVEDHLKTEEELSEEKQILNEMLEVVEQRDSLVALLEEQRLRE 1981 Score = 39.7 bits (91), Expect = 0.015 Identities = 41/183 (22%), Positives = 63/183 (34%), Gaps = 32/183 (17%) Query: 757 KAEGSDRGPESPELPTPSENSMPPGLSTPTASQEGAGPVPDPSQPTRRQIRLSSPERQRL 816 K+ ++ P+ L S+P L P E +P P P+ R++R + ER+ L Sbjct: 1364 KSYSVEKSPQDEGLHLLKPLSIPKRLGLPKPEGEPLS-LPTPRSPSDRELRSAQEERREL 1422 Query: 817 SSLN--------------------------LTPDPEMEPPPKPPRSCSALARHALESSFV 850 SS + LTP PPP P + L R E+ Sbjct: 1423 SSSSGLGLHGSSSNMKTLGSQSFNTSDSAMLTPPSSPPPPPPPGEEPATLRRKLREAEPN 1482 Query: 851 GWGLPVQSPQALVAMEKEEKESP-----FSSEEEEEDVPLDSDVEQALQTFAKTSGTMNN 905 +P P + +E + P S E E++P DVE + S Sbjct: 1483 ASVVPPPLPATWMRPPREPAQPPREEVRKSFVESVEEIPFADDVEDTYDDKTEDSSLQEK 1542 Query: 906 YPT 908 + T Sbjct: 1543 FFT 1545 >gi|170172518 microtubule associated monoxygenase, calponin and LIM domain containing 3 isoform 3 [Homo sapiens] Length = 966 Score = 726 bits (1875), Expect = 0.0 Identities = 402/892 (45%), Positives = 526/892 (58%), Gaps = 79/892 (8%) Query: 8 NPAHAHFESFLQAQLCQDVLSSFQELCGALGLEPGGGLPQYHKIKDQLNYWSAKSLWTKL 67 NPAH F+ F+QA C+ L +FQELC L L+P YHK+K +LNYW AK+LW KL Sbjct: 10 NPAHVLFDRFVQATTCKGTLKAFQELCDHLELKPKDYRSFYHKLKSKLNYWKAKALWAKL 69 Query: 68 DKRAGQPVYQQGRACTSTKCLVVGAGPCGLRVAVELALLGARVVLVEKRTKFSRHNVLHL 127 DKR Y++G+ACT+TKCL++GAGPCGLR A++L+LLGA+VV++EKR FSR+NVLHL Sbjct: 70 DKRGSHKDYKKGKACTNTKCLIIGAGPCGLRTAIDLSLLGAKVVVIEKRDAFSRNNVLHL 129 Query: 128 WPFTIHDLRALGAKKFYGRFCTGTLDHISIRQLQLLLLKVALLLGVEIHWGVTFTGLQPP 187 WPFTIHDLR LGAKKFYG+FC G +DHISIRQLQL+LLKVAL+LG+EIH V F GL P Sbjct: 130 WPFTIHDLRGLGAKKFYGKFCAGAIDHISIRQLQLILLKVALILGIEIHVNVEFQGLIQP 189 Query: 188 PRKGS----GWRAQLQPNPPAQLANYEFDVLISAAGGKFVPEGFKVREMRGKLAIGITAN 243 P GWRA + P ++ YEF+V+I G + EGF+ +E RGKLAI ITAN Sbjct: 190 PEDQENERIGWRALVHPKTHP-VSEYEFEVIIGGDGRRNTLEGFRRKEFRGKLAIAITAN 248 Query: 244 FVNGRTVEETQVPEISGVARIYNQSFFQSLLKATGIDLENIVYYKDDTHYFVMTAKKQCL 303 F+N T E +V EISGVA I+NQ FFQ L +ATGIDLENIVYYKDDTHYFVMTAKKQ L Sbjct: 249 FINRNTTAEAKVEEISGVAFIFNQKFFQELREATGIDLENIVYYKDDTHYFVMTAKKQSL 308 Query: 304 LRLGVLRQDWPDTNRLLGSANVVPEALQRFTRAAADFATHGKLGKLEFAQDAHGQPDVSA 363 L GV+ D+ DT LL NV EAL + R AADF+T +L L+FA + +GQPDV+ Sbjct: 309 LDKGVILHDYADTELLLSRENVDQEALLSYAREAADFSTQQQLPSLDFAINHYGQPDVAM 368 Query: 364 FDFTSMMRAESSARVQEKHGARLLLGLVGDCLVEPFWPLGTGVARGFLAAFDAAWMVKRW 423 FDFT M +E++A V+E++G +LL+ LVGD L+EPFWP+GTG+ARGFLAA D+AWMV+ W Sbjct: 369 FDFTCMYASENAALVREQNGHQLLVALVGDSLLEPFWPMGTGIARGFLAAMDSAWMVRSW 428 Query: 424 AEGAESLEVLAERESLYQLLSQTSPENMHRNVAQYGLDPATRYPNLNLRAVTPNQVRDLY 483 + G LEVLAERES+Y+LL QT+PEN+ +N +QY +DP TRYPN+N+ + P+QVR LY Sbjct: 429 SLGTSPLEVLAERESIYRLLPQTTPENVSKNFSQYSIDPVTRYPNINVNFLRPSQVRHLY 488 Query: 484 DVLAKEPVQRN-----NDKTDTGMPATGSAGTQEELLRWCQEQTAGYPGVHVSDLSSSWA 538 D + + N +T + S +LL WCQ QT GY GV+V+DL+ SW Sbjct: 489 DTGETKDIHLEMESLVNSRTTPKLTRNESVARSSKLLGWCQRQTDGYAGVNVTDLTMSWK 548 Query: 539 DGLALCALVYRLQPGLLEPSELQGLGALEATAWALKVAENELGITPVVSAQ--AVVAGSD 596 GLALCA+++R +P L++ L + A +AE ELGI+P+++ + A V D Sbjct: 549 SGLALCAIIHRYRPDLIDFDSLDEQNVEKNNQLAFDIAEKELGISPIMTGKEMASVGEPD 608 Query: 597 PLGLIAYLSHFHSAFKSMAHSPGPVSQAS-------PGTSSAVLFLSKLQRTLQRSRA-- 647 L ++ YL+ F+ FK S + + T S + FLSKL +T+ R R+ Sbjct: 609 KLSMVMYLTQFYEMFKDSLPSSDTLDLNAEEKAVLIASTRSPISFLSKLGQTISRKRSPK 668 Query: 648 --KENAEDAGGKKLRLEMEAETPSTEVPPDPEPGVPLT---------------------- 683 KE D GK+ + E + P + T Sbjct: 669 DKKEKDLDGAGKRRKTSQSEEEEAPRGHRGERPTLVSTLTDRRMDVAVGNQNKVKYMATQ 728 Query: 684 --------PPSQH--------------QEAGAGDLCALCGEHLYVLERLCVNGHFFHRSC 721 P+Q Q G D C C + +YV+ERL G FFHRSC Sbjct: 729 LLAKFEENAPAQSIGIRRQGSMKKEFPQNLGGSDTCYFCQKRVYVMERLSAEGKFFHRSC 788 Query: 722 FRCHTCEATLWPGGYEQHPGDGHFYCLQH-------LPQTDHKAEGSDRGPES----PEL 770 F+C C TL Y DG FYC H Q A G E+ + Sbjct: 789 FKCEYCATTLRLSAYAYDIEDGKFYCKPHYCYRLSGYAQRKRPAVAPLSGKEAKGPLQDG 848 Query: 771 PTPSENSMPPGLSTPTASQEGAGPVPDPSQPTRRQIRLSSPERQRLSSLNLT 822 T N +++ T G+G V +P+ + +PER L + L+ Sbjct: 849 ATTDANGRANAVASSTERTPGSG-VNGLEEPSIAKRLRGTPERIELENYRLS 899 >gi|209862793 microtubule associated monoxygenase, calponin and LIM domain containing 3 isoform 2 [Homo sapiens] Length = 1073 Score = 687 bits (1772), Expect = 0.0 Identities = 356/710 (50%), Positives = 466/710 (65%), Gaps = 23/710 (3%) Query: 8 NPAHAHFESFLQAQLCQDVLSSFQELCGALGLEPGGGLPQYHKIKDQLNYWSAKSLWTKL 67 NPAH F+ F+QA C+ L +FQELC L L+P YHK+K +LNYW AK+LW KL Sbjct: 10 NPAHVLFDRFVQATTCKGTLKAFQELCDHLELKPKDYRSFYHKLKSKLNYWKAKALWAKL 69 Query: 68 DKRAGQPVYQQGRACTSTKCLVVGAGPCGLRVAVELALLGARVVLVEKRTKFSRHNVLHL 127 DKR Y++G+ACT+TKCL++GAGPCGLR A++L+LLGA+VV++EKR FSR+NVLHL Sbjct: 70 DKRGSHKDYKKGKACTNTKCLIIGAGPCGLRTAIDLSLLGAKVVVIEKRDAFSRNNVLHL 129 Query: 128 WPFTIHDLRALGAKKFYGRFCTGTLDHISIRQLQLLLLKVALLLGVEIHWGVTFTGLQPP 187 WPFTIHDLR LGAKKFYG+FC G +DHISIRQLQL+LLKVAL+LG+EIH V F GL P Sbjct: 130 WPFTIHDLRGLGAKKFYGKFCAGAIDHISIRQLQLILLKVALILGIEIHVNVEFQGLIQP 189 Query: 188 PRKGS----GWRAQLQPNPPAQLANYEFDVLISAAGGKFVPEGFKVREMRGKLAIGITAN 243 P GWRA + P ++ YEF+V+I G + EGF+ +E RGKLAI ITAN Sbjct: 190 PEDQENERIGWRALVHPKTHP-VSEYEFEVIIGGDGRRNTLEGFRRKEFRGKLAIAITAN 248 Query: 244 FVNGRTVEETQVPEISGVARIYNQSFFQSLLKATGIDLENIVYYKDDTHYFVMTAKKQCL 303 F+N T E +V EISGVA I+NQ FFQ L +ATGIDLENIVYYKDDTHYFVMTAKKQ L Sbjct: 249 FINRNTTAEAKVEEISGVAFIFNQKFFQELREATGIDLENIVYYKDDTHYFVMTAKKQSL 308 Query: 304 LRLGVLRQDWPDTNRLLGSANVVPEALQRFTRAAADFATHGKLGKLEFAQDAHGQPDVSA 363 L GV+ D+ DT LL NV EAL + R AADF+T +L L+FA + +GQPDV+ Sbjct: 309 LDKGVILHDYADTELLLSRENVDQEALLSYAREAADFSTQQQLPSLDFAINHYGQPDVAM 368 Query: 364 FDFTSMMRAESSARVQEKHGARLLLGLVGDCLVEPFWPLGTGVARGFLAAFDAAWMVKRW 423 FDFT M +E++A V+E++G +LL+ LVGD L+EPFWP+GTG+ARGFLAA D+AWMV+ W Sbjct: 369 FDFTCMYASENAALVREQNGHQLLVALVGDSLLEPFWPMGTGIARGFLAAMDSAWMVRSW 428 Query: 424 AEGAESLEVLAERESLYQLLSQTSPENMHRNVAQYGLDPATRYPNLNLRAVTPNQVRDLY 483 + G LEVLAERES+Y+LL QT+PEN+ +N +QY +DP TRYPN+N+ + P+QVR LY Sbjct: 429 SLGTSPLEVLAERESIYRLLPQTTPENVSKNFSQYSIDPVTRYPNINVNFLRPSQVRHLY 488 Query: 484 DVLAKEPVQRN-----NDKTDTGMPATGSAGTQEELLRWCQEQTAGYPGVHVSDLSSSWA 538 D + + N +T + S +LL WCQ QT GY GV+V+DL+ SW Sbjct: 489 DTGETKDIHLEMESLVNSRTTPKLTRNESVARSSKLLGWCQRQTDGYAGVNVTDLTMSWK 548 Query: 539 DGLALCALVYRLQPGLLEPSELQGLGALEATAWALKVAENELGITPVVSAQ--AVVAGSD 596 GLALCA+++R +P L++ L + A +AE ELGI+P+++ + A V D Sbjct: 549 SGLALCAIIHRYRPDLIDFDSLDEQNVEKNNQLAFDIAEKELGISPIMTGKEMASVGEPD 608 Query: 597 PLGLIAYLSHFHSAFKSMAHSPGPVSQAS-------PGTSSAVLFLSKLQRTLQRSRA-- 647 L ++ YL+ F+ FK S + + T S + FLSKL +T+ R R+ Sbjct: 609 KLSMVMYLTQFYEMFKDSLPSSDTLDLNAEEKAVLIASTRSPISFLSKLGQTISRKRSPK 668 Query: 648 --KENAEDAGGKKLRLEMEAETPSTEVPPDPEPGVPLTPPSQHQEAGAGD 695 KE D GK+ + E + P + T + + G+ Sbjct: 669 DKKEKDLDGAGKRRKTSQSEEEEAPRGHRGERPTLVSTLTDRRMDVAVGN 718 Score = 67.4 bits (163), Expect = 7e-11 Identities = 29/62 (46%), Positives = 33/62 (53%) Query: 689 QEAGAGDLCALCGEHLYVLERLCVNGHFFHRSCFRCHTCEATLWPGGYEQHPGDGHFYCL 748 Q G D C C + +YV+ERL G FFHRSCF+C C TL Y DG FYC Sbjct: 880 QNLGGSDTCYFCQKRVYVMERLSAEGKFFHRSCFKCEYCATTLRLSAYAYDIEDGKFYCK 939 Query: 749 QH 750 H Sbjct: 940 PH 941 >gi|7662284 microtubule associated monoxygenase, calponin and LIM domain containing 2 [Homo sapiens] Length = 1124 Score = 629 bits (1623), Expect = e-180 Identities = 327/614 (53%), Positives = 420/614 (68%), Gaps = 10/614 (1%) Query: 14 FESFLQAQLCQDVLSSFQELCGALGLEPGGGLPQYHKIKDQLNYWSAKSLWTKLDKRAGQ 73 FE+F+QA C+ L +F L L L+P Y K+K ++ W AK+LW KLDKR Sbjct: 16 FENFVQASTCKGTLQAFNILTRHLDLDPLDHRNFYSKLKSKVTTWKAKALWYKLDKRGSH 75 Query: 74 PVYQQGRACTSTKCLVVGAGPCGLRVAVELALLGARVVLVEKRTKFSRHNVLHLWPFTIH 133 Y++G++CT+TKCL+VG GPCGLR A+ELA LGA+VV+VEKR FSR+NVLHLWPFTIH Sbjct: 76 KEYKRGKSCTNTKCLIVGGGPCGLRTAIELAYLGAKVVVVEKRDSFSRNNVLHLWPFTIH 135 Query: 134 DLRALGAKKFYGRFCTGTLDHISIRQLQLLLLKVALLLGVEIHWGVTFTGLQPPPRKGS- 192 DLR LGAKKFYG+FC G++DHISIRQLQL+L KVAL+LGVEIH V F + PP Sbjct: 136 DLRGLGAKKFYGKFCAGSIDHISIRQLQLILFKVALMLGVEIHVNVEFVKVLEPPEDQEN 195 Query: 193 ---GWRAQLQPNPPAQLANYEFDVLISAAGGKFVPEGFKVREMRGKLAIGITANFVNGRT 249 GWRA+ P + L+ +EFDV+I A G + EGF+ +E RGKLAI ITANF+N + Sbjct: 196 QKIGWRAEFLPTDHS-LSEFEFDVIIGADGRRNTLEGFRRKEFRGKLAIAITANFINRNS 254 Query: 250 VEETQVPEISGVARIYNQSFFQSLLKATGIDLENIVYYKDDTHYFVMTAKKQCLLRLGVL 309 E +V EISGVA I+NQ FFQ L + TGIDLENIVYYKD THYFVMTAKKQ LL GV+ Sbjct: 255 TAEAKVEEISGVAFIFNQKFFQDLKEETGIDLENIVYYKDCTHYFVMTAKKQSLLDKGVI 314 Query: 310 RQDWPDTNRLLGSANVVPEALQRFTRAAADFATHGKLGKLEFAQDAHGQPDVSAFDFTSM 369 D+ DT LL + NV + L + R AADFAT+ +L L+FA + +GQPDV+ FDFT M Sbjct: 315 INDYIDTEMLLCAENVNQDNLLSYAREAADFATNYQLPSLDFAMNHYGQPDVAMFDFTCM 374 Query: 370 MRAESSARVQEKHGARLLLGLVGDCLVEPFWPLGTGVARGFLAAFDAAWMVKRWAEGAES 429 +E++A V+E+ +LL+ LVGD L+EPFWP+GTG ARGFLAAFD AWMVK W +G Sbjct: 375 YASENAALVRERQAHQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMVKSWNQGTPP 434 Query: 430 LEVLAERESLYQLLSQTSPENMHRNVAQYGLDPATRYPNLNLRAVTPNQVRDLY--DVLA 487 LE+LAERESLY+LL QT+PEN+++N QY LDP TRYPNLN V P+QV+ LY L Sbjct: 435 LELLAERESLYRLLPQTTPENINKNFEQYTLDPGTRYPNLNSHCVRPHQVKHLYITKELE 494 Query: 488 KEPVQR-NNDKTDTGMPATGSAGTQEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCAL 546 P++R + + + S +LL WCQ+QT GY V+V+DL++SW GLALCA+ Sbjct: 495 HYPLERLGSVRRSVNLSRKESDIRPSKLLTWCQQQTEGYQHVNVTDLTTSWRSGLALCAI 554 Query: 547 VYRLQPGLLEPSELQGLGALEATAWALKVAENELGITPVVSAQAVVAGSDP--LGLIAYL 604 ++R +P L+ L A+E A VAE E GI PV + + + + +P L ++ YL Sbjct: 555 IHRFRPELINFDSLNEDDAVENNQLAFDVAEREFGIPPVTTGKEMASAQEPDKLSMVMYL 614 Query: 605 SHFHSAFKSMAHSP 618 S F+ F+ P Sbjct: 615 SKFYELFRGTPLRP 628 Score = 70.9 bits (172), Expect = 6e-12 Identities = 48/187 (25%), Positives = 67/187 (35%), Gaps = 41/187 (21%) Query: 606 HFHSAFKSMAHSPGPVSQASPGTSSAVLFLSKLQRTLQRSRAKENAEDAGGKKLRLEMEA 665 HFH + H V + S G +A L L R +A+ + D + + Sbjct: 937 HFHPSHLRTVHPQLTVGKVSSGIGAAAEVLVNLYMNDHRPKAQATSPDLESMRKSFPLNL 996 Query: 666 ETPSTEVPPDPEPGVPLTPPSQHQEAGAGDLCALCGEHLYVLERLCVNGHFFHRSCFRCH 725 G D C C + +YV+ERL GHFFHR CFRC Sbjct: 997 --------------------------GGSDTCYFCKKRVYVMERLSAEGHFFHRECFRCS 1030 Query: 726 TCEATLWPGGYEQHPGDGHFYCLQHL---------------PQTDHKAEGSDRGPESPEL 770 C TL Y +G FYC H + + E + + E+P Sbjct: 1031 ICATTLRLAAYTFDCDEGKFYCKPHFIHCKTNSKQRKRRAELKQQREEEATWQEQEAPRR 1090 Query: 771 PTPSENS 777 TP+E+S Sbjct: 1091 DTPTESS 1097 >gi|31324577 molecule interacting with Rab13 [Homo sapiens] Length = 863 Score = 138 bits (348), Expect = 2e-32 Identities = 100/358 (27%), Positives = 150/358 (41%), Gaps = 49/358 (13%) Query: 508 AGTQEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALE 567 AG + LL WC+ Q GY GV + DLSSS+ DGLA CA+++R +P LL+ L E Sbjct: 2 AGPRGALLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFE 61 Query: 568 ATAWALKVAENELGITPVVSAQAVVAGSDP--LGLIAYLSHFHSAFKSMAHSPGPVSQAS 625 A +VAE ELGI ++ +V+ S P L ++ Y+S +++ F SPG + Sbjct: 62 NNRLAFEVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHF----CSPGQAGVSP 117 Query: 626 PGTSSAVLFLSKLQRTLQRSRAKENAEDAGGKKLRLEMEAETPSTEVPPDPEPGVPLTPP 685 P A + T E+ L + +TPS+ Sbjct: 118 PRKGLAPCSPPSVAPTPVEPEDVAQGEELSSGSLSEQGTGQTPSS--------------- 162 Query: 686 SQHQEAGAGDLCALCGEHLYVLERLCVNGHFFHRSCFRCHTCEATLWPGGYEQHPGDGHF 745 CA C +H+++++R +G +HR CFRC C +TL PG YE P +G F Sbjct: 163 ----------TCAACQQHVHLVQRYLADGRLYHRHCFRCRRCSSTLLPGAYENGPEEGTF 212 Query: 746 YCLQHLPQTDHKAEGSDR-GP--------------ESPELPTPSENSMPPG---LSTPTA 787 C +H + R GP ++ ++P +S P P A Sbjct: 213 VCAEHCARLGPGTRSGTRPGPFSQPKQQHQQQLAEDAKDVPGGGPSSSAPAGAEADGPKA 272 Query: 788 SQEGAGPVPDPSQPTRRQIRLSSPERQRLSSLNLTPDPEMEPPPKPPRSCSALARHAL 845 S E +P + + L+SP R + P P PR S+L + L Sbjct: 273 SPEARPQIPTKPRVPGKLQELASPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQENL 330 Score = 77.4 bits (189), Expect = 7e-14 Identities = 74/300 (24%), Positives = 129/300 (43%), Gaps = 19/300 (6%) Query: 764 GPESPELPTPSENSMPPGLSTPTASQEGAGPVPDPSQPTRRQIRLSSPERQRLSSLNLTP 823 G E E P ++S P + P + S + ++ E+ +S L P Sbjct: 524 GAELLEPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAP 583 Query: 824 DPEMEPPPKPPRSCSALARHALESSFVGWGLPVQSPQAL---VAMEKEEKESPFSSEEEE 880 P+P + CS L VG PV SP + + ++ KE+PF+ + Sbjct: 584 RTRGSSGPQPAKPCSGATPTPL--LLVGDRSPVPSPGSSSPQLQVKSSCKENPFNRKPSP 641 Query: 881 EDVPLDSDVEQALQTFAKTSGTMNNYPTWRRTLLRRAKEEEMKRFCKAQTIQRRLNEIEA 940 P + + + + +P +R + + ++ + I ++ IE Sbjct: 642 AASPATKKATKGSKP-VRPPAPGHGFPLIKRKV-------QADQYIPEEDIHGEMDTIER 693 Query: 941 ALRELEAEGVKLELALRRQSSSPEQQKKL--WVGQLLQLVDKKNSLVAEEAELMITVQEL 998 L LE GV LE LR + + L W +L+ +K+ LV E+EL+ ++ Sbjct: 694 RLDALEHRGVLLEEKLRGGLNEGREDDMLVDW----FKLIHEKHLLVRRESELIYVFKQQ 749 Query: 999 NLEEKQWQLDQELRGYMNREENLKTAADRQAEDQVLRKLVDLVNQRDALIRFQEERRLSE 1058 NLE++Q ++ ELR +N+ E T DR E ++++LV L+ QR+A+I +E R E Sbjct: 750 NLEQRQADVEYELRCLLNKPEKDWTEEDRAREKVLMQELVTLIEQRNAIINCLDEDRQRE 809 >gi|33667117 MICAL-like 2 isoform 1 [Homo sapiens] Length = 904 Score = 130 bits (327), Expect = 7e-30 Identities = 94/345 (27%), Positives = 153/345 (44%), Gaps = 55/345 (15%) Query: 514 LLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATAWAL 573 L +WC++Q GY V++ ++++S+ DGLA CA+++R +P L+ S L+ E A Sbjct: 7 LQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYENNKLAF 66 Query: 574 KVAENELGITPVVSAQAVVAGSDP--LGLIAYLSHFHSAFKSMAHSPGPVSQASPGTSSA 631 +VAE LGI ++ A+ +VA P L ++ Y+S +++ F H P+ G + Sbjct: 67 RVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYF----HGRSPI-----GGMAG 117 Query: 632 VLFLSKLQRTLQRSRAKENAEDAGGKKLRLE---MEAETPSTEVPPDPEPGVPLT----- 683 V + ++++ E+ GKK ++ + + P+ + P P P+ Sbjct: 118 V-----------KRASEDSEEEPSGKKAPVQAAKLPSPAPARKPPLSPAQTNPVVQRRNE 166 Query: 684 ----PPSQHQEAGAGDL----CALCGEHLYVLERLCVNGHFFHRSCFRCHTCEATLWPGG 735 PP + +A AG L C +CG+H+++++R +G +HRSCFRC C TL G Sbjct: 167 GAGGPPPKTDQALAGSLVSSTCGVCGKHVHLVQRHLADGRLYHRSCFRCKQCSCTLHSGA 226 Query: 736 YEQHPGDGHFYCLQHLPQT-------------DHKAEGSDRGPESPELPTPSENSMPPGL 782 Y+ G F C HLP A G D N P Sbjct: 227 YKATGEPGTFVCTSHLPAAASASPKLTGLVPRQPGAMGVDSRTSCSPQKAQEANKARPSA 286 Query: 783 STPTASQEGA----GPVPDPSQPTRRQIRLSSPERQRLSSLNLTP 823 P A A P+P+ + + + SP R S L TP Sbjct: 287 WEPAAGNSPARASVPAAPNPAATSATSVHVRSPARPSESRLAPTP 331 Score = 71.2 bits (173), Expect = 5e-12 Identities = 46/134 (34%), Positives = 73/134 (54%), Gaps = 2/134 (1%) Query: 925 FCKAQTIQRRLNEIEAALRELEAEGVKLELALRRQSSSPEQQKKLWVGQLLQLVDKKNSL 984 + + IQR+L +IE L LE GV+LE LR + + + L V L+ +K L Sbjct: 734 YLSPEEIQRQLQDIERRLDALELRGVELEKRLRA-AEGDDAEDSLMV-DWFWLIHEKQLL 791 Query: 985 VAEEAELMITVQELNLEEKQWQLDQELRGYMNREENLKTAADRQAEDQVLRKLVDLVNQR 1044 + +E+ELM + LEE+Q ++ ELR M + E LK+ +R+ E ++L + V VN R Sbjct: 792 LRQESELMYKSKAQRLEEQQLDIEGELRRLMAKPEALKSLQERRREQELLEQYVSTVNDR 851 Query: 1045 DALIRFQEERRLSE 1058 ++ +E RL E Sbjct: 852 SDIVDSLDEDRLRE 865 >gi|118918413 MICAL C-terminal like [Homo sapiens] Length = 695 Score = 119 bits (298), Expect = 2e-26 Identities = 81/238 (34%), Positives = 126/238 (52%), Gaps = 20/238 (8%) Query: 823 PDPEMEPPPKPPRSCSALARHALESSFVGWGLPVQSPQALVAMEKEEKESPFSSEEEEED 882 P P PPP PP + A +++ P+++ Q A S S++EE Sbjct: 459 PPPPPPPPPPPPTAGGADSKN----------FPLRA-QVTEASSSASSTSSSSADEE--- 504 Query: 883 VPLDSDVEQALQTFAKTSGTMNNYPTWRRTLLRRAKEEEMKRFCKAQTIQRRLNEIEAAL 942 D + +LQ K T+ + + + K+EE+KR KAQ IQR+L E+E Sbjct: 505 ----FDPQLSLQL--KEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQ 558 Query: 943 RELEAEGVKLELALRRQSSSPEQQKKLWVGQLLQLVDKKNSLVAEEAELMITVQELNLEE 1002 R E +GV+LE ALR ++ S Q + + + +LV +KN L+ E+EL+I QEL LE+ Sbjct: 559 RASEIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELED 618 Query: 1003 KQWQLDQELRGYMNREENLKTAADRQAEDQVLRKLVDLVNQRDALIRFQEERRLSELA 1060 Q +L+Q+LR M +EE+ K D E +V +L+ ++ QRD L+ EE+R+ E A Sbjct: 619 HQSRLEQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKA 676 >gi|67782321 spectrin beta isoform a [Homo sapiens] Length = 2328 Score = 76.6 bits (187), Expect = 1e-13 Identities = 40/105 (38%), Positives = 62/105 (59%), Gaps = 1/105 (0%) Query: 511 QEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATA 570 ++ LL WCQ +TAGYP V+V++ +SSW DGLA AL+++ +P L++ +L+ A Sbjct: 176 KDALLLWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDKLKDSNARHNLE 235 Query: 571 WALKVAENELGITPVVSAQAV-VAGSDPLGLIAYLSHFHSAFKSM 614 A VAE +LGI P++ + V D +I Y+ F+ F M Sbjct: 236 HAFNVAERQLGIIPLLDPEDVFTENPDEKSIITYVVAFYHYFSKM 280 >gi|67782319 spectrin beta isoform b [Homo sapiens] Length = 2137 Score = 76.6 bits (187), Expect = 1e-13 Identities = 40/105 (38%), Positives = 62/105 (59%), Gaps = 1/105 (0%) Query: 511 QEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATA 570 ++ LL WCQ +TAGYP V+V++ +SSW DGLA AL+++ +P L++ +L+ A Sbjct: 176 KDALLLWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDKLKDSNARHNLE 235 Query: 571 WALKVAENELGITPVVSAQAV-VAGSDPLGLIAYLSHFHSAFKSM 614 A VAE +LGI P++ + V D +I Y+ F+ F M Sbjct: 236 HAFNVAERQLGIIPLLDPEDVFTENPDEKSIITYVVAFYHYFSKM 280 >gi|170016061 spectrin, beta, non-erythrocytic 5 [Homo sapiens] Length = 3639 Score = 74.3 bits (181), Expect = 6e-13 Identities = 43/114 (37%), Positives = 64/114 (56%), Gaps = 2/114 (1%) Query: 496 DKTDTGMPATGSAGTQEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLL 555 DK + G A T+E LL WCQ +TA Y V+++D S SW+DGL AL++ +P LL Sbjct: 131 DKEEFGASAA-LLSTKEALLVWCQRKTASYTNVNITDFSRSWSDGLGFNALIHAHRPDLL 189 Query: 556 EPSELQGLGALEATAWALKVAENELGITPVVSAQAVVAGS-DPLGLIAYLSHFH 608 + L+ L A+A VAE ELGI ++ + V A D ++ Y+S ++ Sbjct: 190 DYGSLRPDRPLHNLAFAFLVAEQELGIAQLLDPEDVAAAQPDERSIMTYVSLYY 243 >gi|150378549 tangerin [Homo sapiens] Length = 1523 Score = 73.6 bits (179), Expect = 1e-12 Identities = 73/303 (24%), Positives = 126/303 (41%), Gaps = 54/303 (17%) Query: 762 DRGPESPELPTPSE--------NSMPPG-----LSTPTASQEGAGPVPDPSQPTRRQIRL 808 D G E+P P+E + PG L P+ + E P + + +R Sbjct: 1220 DGGAEAPRESRPAEVPAEGLVNGAGAPGGGGVRLRRPSVNGEPGSVPPPRAHGSFSHVRD 1279 Query: 809 SSPERQRLSSLNLTPDPEMEPPPKPPRSCSALARHALESSFVGWGLPVQSPQALVAMEKE 868 + ++R S L + M+ P +A A + S P P + Sbjct: 1280 ADLLKKRRSRLRNSSSFSMDDPDAGAMGAAAAEGQAPDPS------PAPGPPTAA----D 1329 Query: 869 EKESPFSSEEEEEDVPLDSDVEQALQTFAKTSGTMNNYPTWRRTLLRRAKEEEMKRFCKA 928 ++ P S EE P + E LQ F TS Sbjct: 1330 SQQPPGGSSPSEEPPPSPGE-EAGLQRFQDTS---------------------------- 1360 Query: 929 QTIQRRLNEIEAALRELEAEGVKLELALRR--QSSSPEQQKKLWVGQLLQLVDKKNSLVA 986 Q + L +E R+++ ++E+ LR +S + + Q+++ + + LV+KKN+L+ Sbjct: 1361 QYVCAELQALEQEQRQIDGRAAEVEMQLRSLMESGANKLQEEVLIQEWFTLVNKKNALIR 1420 Query: 987 EEAELMITVQELNLEEKQWQLDQELRGYMNREENLKTAADRQAEDQVLRKLVDLVNQRDA 1046 + +L + ++E +LE + L +ELR + E+ KT+A + E +L +LV LVNQRD Sbjct: 1421 RQDQLQLLMEEQDLERRFELLSRELRAMLAIEDWQKTSAQQHREQLLLEELVSLVNQRDE 1480 Query: 1047 LIR 1049 L+R Sbjct: 1481 LVR 1483 Score = 67.4 bits (163), Expect = 7e-11 Identities = 119/562 (21%), Positives = 206/562 (36%), Gaps = 87/562 (15%) Query: 487 AKEPVQRNNDKTDTGMPATGS-AGTQEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCA 545 A P + D+ G A + + + LL WCQE T GY GV +++ ++SW +GLA CA Sbjct: 1015 ASSPEKAEEDRRLPGSQAPPALVSSSQSLLEWCQEVTTGYRGVRITNFTTSWRNGLAFCA 1074 Query: 546 LVYRLQPGLLEPSELQGLGALEATAWALKVAENELGITPVVSAQAVVAGS--DPLGLIAY 603 +++R P ++ + L L + A LG++ ++ +V S D L ++ Y Sbjct: 1075 ILHRFYPDKIDYASLDPLNIKQNNKQAFD-GFAALGVSRLLEPADMVLLSVPDKLIVMTY 1133 Query: 604 LSHFHS-------------------AFKSMAHSPGPVSQASPGTSSAVLFLSKLQRTLQR 644 L + ++ + P P G + L + + Sbjct: 1134 LCQIRAFCTGQELQLVQLEGGGGAGTYRVGSAQPSPPDDLDAGGLAQRLRGHGAEGPQEP 1193 Query: 645 SRAKENAEDAG-GKKLRLEMEAETPSTEVPPDPEPGVPLTPPSQHQEAGAGDLCALCGEH 703 A + A+ A G R + P P P++ GAG G Sbjct: 1194 KEAADRADGAAPGVASRNAVAGRASKDGGAEAPRESRPAEVPAEGLVNGAG----APGGG 1249 Query: 704 LYVLERLCVNGHFFHRSCFRCHTCEATLWPGGYEQHPGDGHFYCLQHLPQTDHKAEGSDR 763 L R VNG PG G F H+ D + R Sbjct: 1250 GVRLRRPSVNGE-----------------PGSVPPPRAHGSF---SHVRDADLLKKRRSR 1289 Query: 764 GPESPELPTPSENSMPPGLSTPTASQEGA----GPVPDPSQPTRRQIRLSSPERQRLSSL 819 NS + P A GA G PDPS S + SS Sbjct: 1290 ----------LRNSSSFSMDDPDAGAMGAAAAEGQAPDPSPAPGPPTAADSQQPPGGSS- 1338 Query: 820 NLTPDPEMEPPPKPPRSCSALARHALESSFVGWGLPVQSPQALVAMEKEEKESPFSSEEE 879 P EPPP P + L R S +V L A+E+E+++ Sbjct: 1339 -----PSEEPPPSPGEE-AGLQRFQDTSQYV--------CAELQALEQEQRQ--IDGRAA 1382 Query: 880 EEDVPLDSDVEQALQTFAKTSGTMNNYPTWRRTLLRRAKEEEMKRFCKAQTIQRRLNEIE 939 E ++ L S +E + + + ++++++ + Q ++RR E Sbjct: 1383 EVEMQLRSLMESGANKLQEEVLIQEWFTLVNKKNALIRRQDQLQLLMEEQDLERR---FE 1439 Query: 940 AALRELEAEGVKLELALRRQSSSPEQQKKLWVGQLLQLVDKKNSLV--AEEAELMITVQE 997 REL A L + +++S+ + +++L + +L+ LV++++ LV + E + ++ Sbjct: 1440 LLSRELRA---MLAIEDWQKTSAQQHREQLLLEELVSLVNQRDELVRDLDHKERIALEED 1496 Query: 998 LNLEEKQWQLDQELRGYMNREE 1019 LE Q ++L ++R E Sbjct: 1497 ERLERGLEQRRRKLSRQLSRRE 1518 Score = 30.4 bits (67), Expect = 9.3 Identities = 17/58 (29%), Positives = 37/58 (63%), Gaps = 1/58 (1%) Query: 1000 LEEKQWQLD-QELRGYMNREENLKTAADRQAEDQVLRKLVDLVNQRDALIRFQEERRL 1056 LE++Q Q+D + M +++ A++ E+ ++++ LVN+++ALIR Q++ +L Sbjct: 1370 LEQEQRQIDGRAAEVEMQLRSLMESGANKLQEEVLIQEWFTLVNKKNALIRRQDQLQL 1427 >gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens] Length = 2390 Score = 72.4 bits (176), Expect = 2e-12 Identities = 39/105 (37%), Positives = 62/105 (59%), Gaps = 1/105 (0%) Query: 511 QEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATA 570 ++ LL WCQ +TAGYP V+V + ++SW DGLA A+V++ +P LL+ L+ A Sbjct: 179 KDALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQ 238 Query: 571 WALKVAENELGITPVVSAQAV-VAGSDPLGLIAYLSHFHSAFKSM 614 A +AE ELG+T ++ + V V D +I Y++ ++ F M Sbjct: 239 NAFNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKM 283 >gi|4557241 actinin, alpha 3 [Homo sapiens] Length = 901 Score = 71.2 bits (173), Expect = 5e-12 Identities = 39/103 (37%), Positives = 62/103 (60%), Gaps = 2/103 (1%) Query: 511 QEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATA 570 +E LL WCQ +TA Y V+V + +SW DGLALCAL++R +P L++ ++L+ + Sbjct: 161 KEGLLLWCQRKTAPYRNVNVQNFHTSWKDGLALCALIHRHRPDLIDYAKLRKDDPIGNLN 220 Query: 571 WALKVAENELGITPVVSAQAVV--AGSDPLGLIAYLSHFHSAF 611 A +VAE L I ++ A+ +V D ++ Y+S F+ AF Sbjct: 221 TAFEVAEKYLDIPKMLDAEDIVNTPKPDEKAIMTYVSCFYHAF 263 >gi|4501893 actinin, alpha 2 [Homo sapiens] Length = 894 Score = 71.2 bits (173), Expect = 5e-12 Identities = 37/103 (35%), Positives = 61/103 (59%), Gaps = 2/103 (1%) Query: 511 QEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATA 570 +E LL WCQ +TA Y V++ + +SW DGL LCAL++R +P L++ S+L + Sbjct: 154 KEGLLLWCQRKTAPYRNVNIQNFHTSWKDGLGLCALIHRHRPDLIDYSKLNKDDPIGNIN 213 Query: 571 WALKVAENELGITPVVSAQAVV--AGSDPLGLIAYLSHFHSAF 611 A+++AE L I ++ A+ +V D ++ Y+S F+ AF Sbjct: 214 LAMEIAEKHLDIPKMLDAEDIVNTPKPDERAIMTYVSCFYHAF 256 Score = 30.8 bits (68), Expect = 7.1 Identities = 40/212 (18%), Positives = 92/212 (43%), Gaps = 16/212 (7%) Query: 856 VQSPQALVAMEKEEKES-PFSSEEEEEDVPLDSDVEQALQTFAKTSGTMNNYPTWRRTLL 914 ++ Q+L+ ++ K + P + E + + + ++VE+ +Q++ + N Y T L Sbjct: 548 IEEIQSLITAHEQFKATLPEADGERQSIMAIQNEVEKVIQSYNIRISSSNPYSTVTMDEL 607 Query: 915 RRAKEEEMKRF--CKAQTIQRRLNEIEAALRELEAEGVKLELALRRQSSSPEQQKKL--- 969 R K +++K+ + Q++Q L R+ E ++ + A + + P Q K+ Sbjct: 608 -RTKWDKVKQLVPIRDQSLQEEL------ARQHANERLRRQFAAQANAIGPWIQNKMEEI 660 Query: 970 ---WVGQLLQLVDKKNSLVAEEAELMITVQELNLEEKQWQLDQELRGYMNREENLKTAAD 1026 + L D+ N L E ++ ++ E QL QE + N+ N Sbjct: 661 ARSSIQITGALEDQMNQLKQYEHNIINYKNNIDKLEGDHQLIQEALVFDNKHTNYTMEHI 720 Query: 1027 RQAEDQVLRKLVDLVNQRDALIRFQEERRLSE 1058 R + +L + +N+ + I ++ + +++ Sbjct: 721 RVGWELLLTTIARTINEVETQILTRDAKGITQ 752 >gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [Homo sapiens] Length = 2564 Score = 69.7 bits (169), Expect = 1e-11 Identities = 37/105 (35%), Positives = 60/105 (57%), Gaps = 1/105 (0%) Query: 511 QEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATA 570 ++ LL WCQ +TAGYP V++ + ++SW DGLA AL++R +P L++ S+L A Sbjct: 183 KDALLLWCQMKTAGYPEVNIQNFTTSWRDGLAFNALIHRHRPDLVDFSKLTKSNANYNLQ 242 Query: 571 WALKVAENELGITPVVSAQAV-VAGSDPLGLIAYLSHFHSAFKSM 614 A + AE LG+ ++ + V + D +I Y+ F+ F M Sbjct: 243 RAFRTAEQHLGLARLLDPEDVNMEAPDEKSIITYVVSFYHYFSKM 287 Score = 32.3 bits (72), Expect = 2.4 Identities = 27/116 (23%), Positives = 56/116 (48%), Gaps = 9/116 (7%) Query: 929 QTIQRRLNEIEAALRELEAEGVKLELALRRQSS-----SPEQQKKLWVGQLLQLVDKKNS 983 Q +Q+ + + + RE++A G +LE L R + SPE + V + L+ + + Sbjct: 1548 QAVQQHIKKNQGLRREIQAHGPRLEEVLERAGALASLRSPEAEA---VRRGLEQLQSAWA 1604 Query: 984 LVAEEAELMITVQELNLEEKQWQLD-QELRGYMNREENLKTAADRQAEDQVLRKLV 1038 + E AE V + + +Q+ D E+ ++ +E L + D+ ++Q +L+ Sbjct: 1605 GLREAAERRQQVLDAAFQVEQYYFDVAEVEAWLGEQELLMMSEDKGKDEQSTLQLL 1660 >gi|194097352 actinin, alpha 1 isoform c [Homo sapiens] Length = 887 Score = 69.3 bits (168), Expect = 2e-11 Identities = 38/103 (36%), Positives = 58/103 (56%), Gaps = 2/103 (1%) Query: 511 QEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATA 570 +E LL WCQ +TA Y V++ + SW DGL CAL++R +P L++ +L+ L Sbjct: 147 KEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTNLN 206 Query: 571 WALKVAENELGITPVVSAQAVV--AGSDPLGLIAYLSHFHSAF 611 A VAE L I ++ A+ +V A D ++ Y+S F+ AF Sbjct: 207 TAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAF 249 >gi|194097350 actinin, alpha 1 isoform a [Homo sapiens] Length = 914 Score = 69.3 bits (168), Expect = 2e-11 Identities = 38/103 (36%), Positives = 58/103 (56%), Gaps = 2/103 (1%) Query: 511 QEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATA 570 +E LL WCQ +TA Y V++ + SW DGL CAL++R +P L++ +L+ L Sbjct: 147 KEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTNLN 206 Query: 571 WALKVAENELGITPVVSAQAVV--AGSDPLGLIAYLSHFHSAF 611 A VAE L I ++ A+ +V A D ++ Y+S F+ AF Sbjct: 207 TAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAF 249 >gi|4501891 actinin, alpha 1 isoform b [Homo sapiens] Length = 892 Score = 69.3 bits (168), Expect = 2e-11 Identities = 38/103 (36%), Positives = 58/103 (56%), Gaps = 2/103 (1%) Query: 511 QEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATA 570 +E LL WCQ +TA Y V++ + SW DGL CAL++R +P L++ +L+ L Sbjct: 147 KEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTNLN 206 Query: 571 WALKVAENELGITPVVSAQAVV--AGSDPLGLIAYLSHFHSAF 611 A VAE L I ++ A+ +V A D ++ Y+S F+ AF Sbjct: 207 TAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAF 249 >gi|33188445 microfilament and actin filament cross-linker protein isoform a [Homo sapiens] Length = 5430 Score = 68.2 bits (165), Expect = 4e-11 Identities = 39/108 (36%), Positives = 61/108 (56%), Gaps = 2/108 (1%) Query: 505 TGSAGTQEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLG 564 +G +E+LL W Q+ TAGY G+ ++ SS W+DG AL++R +P L++ +Q Sbjct: 191 SGDMSAKEKLLLWTQKVTAGYTGIKCTNFSSCWSDGKMFNALIHRYRPDLVDMERVQIQS 250 Query: 565 ALEATAWALKVAENELGITPVVSAQAV-VAGSDPLGLIAYLSHFHSAF 611 E A +VAE LG+T ++ A+ V V D +I Y+S + AF Sbjct: 251 NRENLEQAFEVAE-RLGVTRLLDAEDVDVPSPDEKSVITYVSSIYDAF 297 >gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo sapiens] Length = 2155 Score = 67.4 bits (163), Expect = 7e-11 Identities = 34/105 (32%), Positives = 61/105 (58%), Gaps = 1/105 (0%) Query: 511 QEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATA 570 ++ LL WCQ +TAGYP V++ + ++SW DG+A AL+++ +P L++ +L+ A Sbjct: 163 KDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQ 222 Query: 571 WALKVAENELGITPVVSAQAV-VAGSDPLGLIAYLSHFHSAFKSM 614 A +AE LG+T ++ + + V D +I Y+ ++ F M Sbjct: 223 NAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYVVTYYHYFSKM 267 >gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo sapiens] Length = 2364 Score = 67.4 bits (163), Expect = 7e-11 Identities = 34/105 (32%), Positives = 61/105 (58%), Gaps = 1/105 (0%) Query: 511 QEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATA 570 ++ LL WCQ +TAGYP V++ + ++SW DG+A AL+++ +P L++ +L+ A Sbjct: 176 KDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQ 235 Query: 571 WALKVAENELGITPVVSAQAV-VAGSDPLGLIAYLSHFHSAFKSM 614 A +AE LG+T ++ + + V D +I Y+ ++ F M Sbjct: 236 NAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYVVTYYHYFSKM 280 >gi|12025678 actinin, alpha 4 [Homo sapiens] Length = 911 Score = 66.6 bits (161), Expect = 1e-10 Identities = 39/103 (37%), Positives = 59/103 (57%), Gaps = 2/103 (1%) Query: 511 QEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATA 570 +E LL WCQ +TA Y V+V + SW DGLA AL++R +P L+E +L+ + Sbjct: 166 KEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPELIEYDKLRKDDPVTNLN 225 Query: 571 WALKVAENELGITPVVSAQAVV--AGSDPLGLIAYLSHFHSAF 611 A +VAE L I ++ A+ +V A D ++ Y+S F+ AF Sbjct: 226 NAFEVAEKYLDIPKMLDAEDIVNTARPDEKAIMTYVSSFYHAF 268 >gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5 [Homo sapiens] Length = 6907 Score = 66.2 bits (160), Expect = 2e-10 Identities = 48/179 (26%), Positives = 84/179 (46%), Gaps = 5/179 (2%) Query: 481 DLYDVLAKEPVQRNNDKTDTGMPATGSAGTQEELLRWCQEQTAGYPGVHVSDLSSSWADG 540 D V+ P K + + A ++ LL W QEQ A Y V+V+D SSW +G Sbjct: 154 DDVSVVDSSPASSPPAKKCSKVQARWQMSARKALLLWAQEQCATYESVNVTDFKSSWRNG 213 Query: 541 LALCALVYRLQPGLLEPSELQGLGALEATAWALKVAENELGITPVVSAQAV-VAGSDPLG 599 +A A+++ L+P L++ ++ + A ++AE EL I ++ + V V D Sbjct: 214 MAFLAIIHALRPDLIDMKSVKHRSNKDNLREAFRIAEQELKIPRLLEPEDVDVVDPDEKS 273 Query: 600 LIAYLSHFHSAFKSMAHSPGPVSQASPGTSSAVLFLSKLQRTLQRSRAKENAEDAGGKK 658 ++ Y++ F K +PG +A A+ +L+ LQ+ + K++ D KK Sbjct: 274 IMTYVAQFLQYSKD---APGTGEEAQGKVKDAMGWLT-LQKEKLQKLLKDSENDTYFKK 328 Score = 30.8 bits (68), Expect = 7.1 Identities = 41/192 (21%), Positives = 80/192 (41%), Gaps = 21/192 (10%) Query: 885 LDSDVEQALQTFA---KTSGTMNNYPTWRRTLLRRAKEEEMKRFCKAQTIQRRLNEIEAA 941 + S V++ +TFA + M+N TW + + + C Q IQ+RL E + Sbjct: 6010 IGSRVKKLKETFAFIQQLDKNMSNLRTWLARIESELSKPVVYDVCDDQEIQKRLAEQQDL 6069 Query: 942 LRELEAEGVKLE-------LALRRQSSSPEQQKKLWVGQLLQLVDKK-NSLVAEEAELMI 993 R++E +E + L + + + + Q + +D++ ++ A E + Sbjct: 6070 QRDIEQHSAGVESVFNICDVLLHDSDACANETECDSIQQTTRSLDRRWRNICAMSMERRM 6129 Query: 994 TVQELNLEEKQWQLDQELRGYMNREENLKTAADRQA----EDQVLRKLVDLVNQRDALIR 1049 ++E W+L Q+ +R E+ +A+R A +VL +R + Sbjct: 6130 KIEE------TWRLWQKFLDDYSRFEDWLKSAERTAACPNSSEVLYTSAKEELKRFEAFQ 6183 Query: 1050 FQEERRLSELAL 1061 Q RL++L L Sbjct: 6184 RQIHERLTQLEL 6195 Score = 30.4 bits (67), Expect = 9.3 Identities = 31/145 (21%), Positives = 67/145 (46%), Gaps = 20/145 (13%) Query: 920 EEMKRFCKAQTIQRRLNEIEA---ALRE--------LEAEGVKLELALRRQSSSPEQQKK 968 EE K F +I+R L+E++ LRE + A +KL AL P Q + Sbjct: 341 EEKKSFLDVLSIKRDLDELDKDHLQLREAWDGLDHQINAWKIKLNYAL----PPPLHQTE 396 Query: 969 LWVGQLLQLVDKKNSLVAEEAELMITVQE-----LNLEEKQWQLDQELRGYMNREENLKT 1023 W+ ++ +L+D+ S + ++ + +QE +L ++ L + N++EN Sbjct: 397 AWLQEVEELMDEDLSASQDHSQAVTLIQEKMTLFKSLMDRFEHHSNILLTFENKDENHLP 456 Query: 1024 AADRQAEDQVLRKLVDLVNQRDALI 1048 +++ R++ +++ ++ L+ Sbjct: 457 LVPPNKLEEMKRRINNILEKKFILL 481 >gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1 [Homo sapiens] Length = 6885 Score = 66.2 bits (160), Expect = 2e-10 Identities = 48/179 (26%), Positives = 84/179 (46%), Gaps = 5/179 (2%) Query: 481 DLYDVLAKEPVQRNNDKTDTGMPATGSAGTQEELLRWCQEQTAGYPGVHVSDLSSSWADG 540 D V+ P K + + A ++ LL W QEQ A Y V+V+D SSW +G Sbjct: 154 DDVSVVDSSPASSPPAKKCSKVQARWQMSARKALLLWAQEQCATYESVNVTDFKSSWRNG 213 Query: 541 LALCALVYRLQPGLLEPSELQGLGALEATAWALKVAENELGITPVVSAQAV-VAGSDPLG 599 +A A+++ L+P L++ ++ + A ++AE EL I ++ + V V D Sbjct: 214 MAFLAIIHALRPDLIDMKSVKHRSNKDNLREAFRIAEQELKIPRLLEPEDVDVVDPDEKS 273 Query: 600 LIAYLSHFHSAFKSMAHSPGPVSQASPGTSSAVLFLSKLQRTLQRSRAKENAEDAGGKK 658 ++ Y++ F K +PG +A A+ +L+ LQ+ + K++ D KK Sbjct: 274 IMTYVAQFLQYSKD---APGTGEEAQGKVKDAMGWLT-LQKEKLQKLLKDSENDTYFKK 328 Score = 30.8 bits (68), Expect = 7.1 Identities = 41/192 (21%), Positives = 80/192 (41%), Gaps = 21/192 (10%) Query: 885 LDSDVEQALQTFA---KTSGTMNNYPTWRRTLLRRAKEEEMKRFCKAQTIQRRLNEIEAA 941 + S V++ +TFA + M+N TW + + + C Q IQ+RL E + Sbjct: 6010 IGSRVKKLKETFAFIQQLDKNMSNLRTWLARIESELSKPVVYDVCDDQEIQKRLAEQQDL 6069 Query: 942 LRELEAEGVKLE-------LALRRQSSSPEQQKKLWVGQLLQLVDKK-NSLVAEEAELMI 993 R++E +E + L + + + + Q + +D++ ++ A E + Sbjct: 6070 QRDIEQHSAGVESVFNICDVLLHDSDACANETECDSIQQTTRSLDRRWRNICAMSMERRM 6129 Query: 994 TVQELNLEEKQWQLDQELRGYMNREENLKTAADRQA----EDQVLRKLVDLVNQRDALIR 1049 ++E W+L Q+ +R E+ +A+R A +VL +R + Sbjct: 6130 KIEE------TWRLWQKFLDDYSRFEDWLKSAERTAACPNSSEVLYTSAKEELKRFEAFQ 6183 Query: 1050 FQEERRLSELAL 1061 Q RL++L L Sbjct: 6184 RQIHERLTQLEL 6195 Score = 30.4 bits (67), Expect = 9.3 Identities = 31/145 (21%), Positives = 67/145 (46%), Gaps = 20/145 (13%) Query: 920 EEMKRFCKAQTIQRRLNEIEA---ALRE--------LEAEGVKLELALRRQSSSPEQQKK 968 EE K F +I+R L+E++ LRE + A +KL AL P Q + Sbjct: 341 EEKKSFLDVLSIKRDLDELDKDHLQLREAWDGLDHQINAWKIKLNYAL----PPPLHQTE 396 Query: 969 LWVGQLLQLVDKKNSLVAEEAELMITVQE-----LNLEEKQWQLDQELRGYMNREENLKT 1023 W+ ++ +L+D+ S + ++ + +QE +L ++ L + N++EN Sbjct: 397 AWLQEVEELMDEDLSASQDHSQAVTLIQEKMTLFKSLMDRFEHHSNILLTFENKDENHLP 456 Query: 1024 AADRQAEDQVLRKLVDLVNQRDALI 1048 +++ R++ +++ ++ L+ Sbjct: 457 LVPPNKLEEMKRRINNILEKKFILL 481 >gi|116517305 cysteine-rich protein 3 [Homo sapiens] Length = 204 Score = 62.4 bits (150), Expect = 2e-09 Identities = 34/89 (38%), Positives = 45/89 (50%), Gaps = 7/89 (7%) Query: 667 TPSTEVPPDPEPGVPL---TPPSQHQEAGAGDLCALCGEHLYVLERLCVNGHFFHRSCFR 723 +PS+ PP P G+P +PP G LC CGE +Y E++ G +HR C R Sbjct: 91 SPSSFSPPRPRTGLPQGKKSPPHMKTFTGETSLCPGCGEPVYFAEKVMSLGRNWHRPCLR 150 Query: 724 CHTCEATLWPGGYEQHPGDGHFYCLQHLP 752 C C TL G + +H DG YC H+P Sbjct: 151 CQRCHKTLTAGSHAEH--DGVPYC--HVP 175 Score = 47.0 bits (110), Expect = 1e-04 Identities = 33/115 (28%), Positives = 49/115 (42%), Gaps = 24/115 (20%) Query: 697 CALCGEHLYVLERLCVNGHFFHRSCFRCHTCEATLWPGGYEQHPGDGHFYCLQHLPQTDH 756 C C + ++ E++ G +HR C +C C + L PGG+ +H +G YC H P Sbjct: 5 CPRCQQPVFFAEKVSSLGKNWHRFCLKCERCHSILSPGGHAEH--NGRPYC--HKP---- 56 Query: 757 KAEGSDRGPESPEL----------PTPSENSMPPGLSTPTASQEGAGPVPDPSQP 801 G+ GP + PTPS PG +TP + + P P P Sbjct: 57 -CYGALFGPRGVNIGGVGSYLYNPPTPS-----PGCTTPLSPSSFSPPRPRTGLP 105 >gi|224451082 cytospin A [Homo sapiens] Length = 1117 Score = 60.1 bits (144), Expect = 1e-08 Identities = 45/179 (25%), Positives = 82/179 (45%), Gaps = 12/179 (6%) Query: 443 LSQTSPENMHRNV-AQYGLDPATRYPNLNLRAVTPNQVRDLYDVLAKEPVQRNNDKTDTG 501 +S+ S E + R++ AQ G PA+ + + +P + P R+ + + Sbjct: 943 VSRRSSEEVKRDISAQEGASPASL---MAMGTTSPQLSLSSSPTASVTPTTRSRIREERK 999 Query: 502 MPATGSA-----GTQEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLE 556 P + A + LL+WCQ++T GY + +++ SSSW DGLA CAL++ P + Sbjct: 1000 DPLSALAREYGGSKRNALLKWCQKKTEGYQNIDITNFSSSWNDGLAFCALLHTYLPAHIP 1059 Query: 557 PSELQGLGALEATAWALKVAENELGITPVVSAQAVVAGSDP--LGLIAYLSHFHSAFKS 613 EL A + AE+ +GI + +V P ++ Y++ + F++ Sbjct: 1060 YQELNSQDKRRNFMLAFQAAES-VGIKSTLDINEMVRTERPDWQNVMLYVTAIYKYFET 1117 >gi|224451080 cytospin A [Homo sapiens] Length = 1117 Score = 60.1 bits (144), Expect = 1e-08 Identities = 45/179 (25%), Positives = 82/179 (45%), Gaps = 12/179 (6%) Query: 443 LSQTSPENMHRNV-AQYGLDPATRYPNLNLRAVTPNQVRDLYDVLAKEPVQRNNDKTDTG 501 +S+ S E + R++ AQ G PA+ + + +P + P R+ + + Sbjct: 943 VSRRSSEEVKRDISAQEGASPASL---MAMGTTSPQLSLSSSPTASVTPTTRSRIREERK 999 Query: 502 MPATGSA-----GTQEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLE 556 P + A + LL+WCQ++T GY + +++ SSSW DGLA CAL++ P + Sbjct: 1000 DPLSALAREYGGSKRNALLKWCQKKTEGYQNIDITNFSSSWNDGLAFCALLHTYLPAHIP 1059 Query: 557 PSELQGLGALEATAWALKVAENELGITPVVSAQAVVAGSDP--LGLIAYLSHFHSAFKS 613 EL A + AE+ +GI + +V P ++ Y++ + F++ Sbjct: 1060 YQELNSQDKRRNFMLAFQAAES-VGIKSTLDINEMVRTERPDWQNVMLYVTAIYKYFET 1117 >gi|169218211 PREDICTED: similar to plectin 1, partial [Homo sapiens] Length = 1369 Score = 60.1 bits (144), Expect = 1e-08 Identities = 33/101 (32%), Positives = 55/101 (54%), Gaps = 1/101 (0%) Query: 511 QEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATA 570 +E+LL W Q GY G+ + +SSW DG A+++R +P L++ +++ LE Sbjct: 294 KEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNAIIHRHKPLLIDMNKVYRQTNLENLD 353 Query: 571 WALKVAENELGITPVVSAQAV-VAGSDPLGLIAYLSHFHSA 610 A VAE +LG+T ++ + V V D +I Y+S + A Sbjct: 354 QAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVSSLYDA 394 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.133 0.397 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 45,952,473 Number of Sequences: 37866 Number of extensions: 2473365 Number of successful extensions: 17428 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 121 Number of HSP's successfully gapped in prelim test: 652 Number of HSP's that attempted gapping in prelim test: 14422 Number of HSP's gapped (non-prelim): 3450 length of query: 1067 length of database: 18,247,518 effective HSP length: 113 effective length of query: 954 effective length of database: 13,968,660 effective search space: 13326101640 effective search space used: 13326101640 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.