Guide to the Human Genome
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Search of human proteins with 19923268

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19923268 protein-kinase, interferon-inducible double
stranded RNA dependent inhibitor, repressor of (P58 repressor) [Homo
sapiens]
         (761 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19923268 protein-kinase, interferon-inducible double stranded...  1536   0.0  
gi|113205089 zinc finger, MYM domain containing 1 [Homo sapiens]      145   1e-34
gi|13899259 THAP domain containing, apoptosis associated protein...    66   1e-10
gi|194440668 THAP domain containing 5 isoform 1 [Homo sapiens]         52   3e-06
gi|56788351 THAP domain containing 7 isoform 2 [Homo sapiens]          49   2e-05
gi|56788349 THAP domain containing 7 isoform 1 [Homo sapiens]          49   2e-05
gi|31982895 THAP domain containing 4 [Homo sapiens]                    46   1e-04
gi|46195755 SCAN domain containing 3 [Homo sapiens]                    46   1e-04
gi|21389507 THAP domain containing 6 [Homo sapiens]                    44   7e-04
gi|40354197 THAP domain containing 11 [Homo sapiens]                   43   0.001
gi|22749337 THAP domain containing 8 [Homo sapiens]                    42   0.002
gi|8922446 THAP domain containing, apoptosis associated protein ...    40   0.008
gi|94536788 THAP domain containing 9 [Homo sapiens]                    40   0.011
gi|15149465 caldesmon 1 isoform 5 [Homo sapiens]                       39   0.023
gi|15149463 caldesmon 1 isoform 4 [Homo sapiens]                       39   0.023
gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]                       39   0.023
gi|4826657 caldesmon 1 isoform 2 [Homo sapiens]                        39   0.023
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]                       39   0.023
gi|33356128 NMDA receptor regulated 1-like protein isoform 1 [Ho...    38   0.031
gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapi...    38   0.040
gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]     37   0.068
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    36   0.12 
gi|28460688 taxilin [Homo sapiens]                                     36   0.15 
gi|8923271 coiled-coil domain containing 49 [Homo sapiens]             36   0.15 
gi|197276647 leucine rich repeat (in FLII) interacting protein 2...    35   0.20 
gi|5453726 leucine rich repeat (in FLII) interacting protein 2 i...    35   0.20 
gi|124249396 coiled-coil domain containing 30 [Homo sapiens]           35   0.26 
gi|15559209 interleukin 33 [Homo sapiens]                              35   0.34 
gi|149773449 zinc finger protein 862 [Homo sapiens]                    35   0.34 
gi|19924131 RAD50 homolog isoform 2 [Homo sapiens]                     34   0.44 

>gi|19923268 protein-kinase, interferon-inducible double stranded
           RNA dependent inhibitor, repressor of (P58 repressor)
           [Homo sapiens]
          Length = 761

 Score = 1536 bits (3978), Expect = 0.0
 Identities = 761/761 (100%), Positives = 761/761 (100%)

Query: 1   MPNFCAAPNCTRKSTQSDLAFFRFPRDPARCQKWVENCRRADLEDKTPDQLNKHYRLCAK 60
           MPNFCAAPNCTRKSTQSDLAFFRFPRDPARCQKWVENCRRADLEDKTPDQLNKHYRLCAK
Sbjct: 1   MPNFCAAPNCTRKSTQSDLAFFRFPRDPARCQKWVENCRRADLEDKTPDQLNKHYRLCAK 60

Query: 61  HFETSMICRTSPYRTVLRDNAIPTIFDLTSHLNNPHSRHRKRIKELSEDEIRTLKQKKID 120
           HFETSMICRTSPYRTVLRDNAIPTIFDLTSHLNNPHSRHRKRIKELSEDEIRTLKQKKID
Sbjct: 61  HFETSMICRTSPYRTVLRDNAIPTIFDLTSHLNNPHSRHRKRIKELSEDEIRTLKQKKID 120

Query: 121 ETSEQEQKHKETNNSNAQNPSEEEGEGQDEDILPLTLEEKENKEYLKSLFEILILMGKQN 180
           ETSEQEQKHKETNNSNAQNPSEEEGEGQDEDILPLTLEEKENKEYLKSLFEILILMGKQN
Sbjct: 121 ETSEQEQKHKETNNSNAQNPSEEEGEGQDEDILPLTLEEKENKEYLKSLFEILILMGKQN 180

Query: 181 IPLDGHEADEIPEGLFTPDNFQALLECRINSGEEVLRKRFETTAVNTLFCSKTQQRQMLE 240
           IPLDGHEADEIPEGLFTPDNFQALLECRINSGEEVLRKRFETTAVNTLFCSKTQQRQMLE
Sbjct: 181 IPLDGHEADEIPEGLFTPDNFQALLECRINSGEEVLRKRFETTAVNTLFCSKTQQRQMLE 240

Query: 241 ICESCIREETLREVRDSHFFSIITDDVVDIAGEEHLPVLVRFVDESHNLREEFIGFLPYE 300
           ICESCIREETLREVRDSHFFSIITDDVVDIAGEEHLPVLVRFVDESHNLREEFIGFLPYE
Sbjct: 241 ICESCIREETLREVRDSHFFSIITDDVVDIAGEEHLPVLVRFVDESHNLREEFIGFLPYE 300

Query: 301 ADAEILAVKFHTMITEKWGLNMEYCRGQAYIVSSGFSSKMKVVASRLLEKYPQAIYTLCS 360
           ADAEILAVKFHTMITEKWGLNMEYCRGQAYIVSSGFSSKMKVVASRLLEKYPQAIYTLCS
Sbjct: 301 ADAEILAVKFHTMITEKWGLNMEYCRGQAYIVSSGFSSKMKVVASRLLEKYPQAIYTLCS 360

Query: 361 SCALNMWLAKSVPVMGVSVALGTIEEVCSFFHRSPQLLLELDNVISVLFQNSKERGKELK 420
           SCALNMWLAKSVPVMGVSVALGTIEEVCSFFHRSPQLLLELDNVISVLFQNSKERGKELK
Sbjct: 361 SCALNMWLAKSVPVMGVSVALGTIEEVCSFFHRSPQLLLELDNVISVLFQNSKERGKELK 420

Query: 421 EICHSQWTGRHDAFEILVELLQALVLCLDGINSDTNIRWNNYIAGRAFVLCSAVSDFDFI 480
           EICHSQWTGRHDAFEILVELLQALVLCLDGINSDTNIRWNNYIAGRAFVLCSAVSDFDFI
Sbjct: 421 EICHSQWTGRHDAFEILVELLQALVLCLDGINSDTNIRWNNYIAGRAFVLCSAVSDFDFI 480

Query: 481 VTIVVLKNVLSFTRAFGKNLQGQTSDVFFAAGSLTAVLHSLNEVMENIEVYHEFWFEEAT 540
           VTIVVLKNVLSFTRAFGKNLQGQTSDVFFAAGSLTAVLHSLNEVMENIEVYHEFWFEEAT
Sbjct: 481 VTIVVLKNVLSFTRAFGKNLQGQTSDVFFAAGSLTAVLHSLNEVMENIEVYHEFWFEEAT 540

Query: 541 NLATKLDIQMKLPGKFRRAHQGNLESQLTSESYYKETLSVPTVEHIIQELKDIFSEQHLK 600
           NLATKLDIQMKLPGKFRRAHQGNLESQLTSESYYKETLSVPTVEHIIQELKDIFSEQHLK
Sbjct: 541 NLATKLDIQMKLPGKFRRAHQGNLESQLTSESYYKETLSVPTVEHIIQELKDIFSEQHLK 600

Query: 601 ALKCLSLVPSVMGQLKFNTSEEHHADMYRSDLPNPDTLSAELHCWRIKWKHRGKDIELPS 660
           ALKCLSLVPSVMGQLKFNTSEEHHADMYRSDLPNPDTLSAELHCWRIKWKHRGKDIELPS
Sbjct: 601 ALKCLSLVPSVMGQLKFNTSEEHHADMYRSDLPNPDTLSAELHCWRIKWKHRGKDIELPS 660

Query: 661 TIYEALHLPDIKFFPNVYALLKVLCILPVMKVENERYENGRKRLKAYLRNTLTDQRSSNL 720
           TIYEALHLPDIKFFPNVYALLKVLCILPVMKVENERYENGRKRLKAYLRNTLTDQRSSNL
Sbjct: 661 TIYEALHLPDIKFFPNVYALLKVLCILPVMKVENERYENGRKRLKAYLRNTLTDQRSSNL 720

Query: 721 ALLNINFDIKHDLDLMVDTYIKLYTSKSELPTDNSETVENT 761
           ALLNINFDIKHDLDLMVDTYIKLYTSKSELPTDNSETVENT
Sbjct: 721 ALLNINFDIKHDLDLMVDTYIKLYTSKSELPTDNSETVENT 761


>gi|113205089 zinc finger, MYM domain containing 1 [Homo sapiens]
          Length = 1142

 Score =  145 bits (366), Expect = 1e-34
 Identities = 154/616 (25%), Positives = 276/616 (44%), Gaps = 54/616 (8%)

Query: 146  EGQDEDILPLTLEEKE-NKEYLKSLFEILILMGKQNIPLDGHE--ADEIPEGLFTPDNFQ 202
            +G   D L +  ++ E NK+YLK + E ++ +GKQ +PL G++     + +G     NF 
Sbjct: 533  DGAVSDDLSIHSKQIEGNKKYLKLIIENILFLGKQCLPLRGNDQSVSSVNKG-----NFL 587

Query: 203  ALLECRI-NSGEEVLRKRFETTAVNTLFCSKTQ-QRQMLEICESCIREETLREVRDSHFF 260
             LLE R  + GEE  R     + V+  F + TQ Q  ++EI ++ + ++ + E+ DS  F
Sbjct: 588  ELLEMRAKDKGEETFR--LMNSQVD--FYNSTQIQSDIIEIIKTEMLQDIVNEINDSSAF 643

Query: 261  SIITDDVVDIAGEEHLPVLVRFVDESHN---LREEFIGFLPYEADAEILAVKFHTMIT-- 315
            SII D+ ++ A +E L + VR+  +S     ++E F+GF+  E   E+     H  I   
Sbjct: 644  SIICDETINSAMKEQLSICVRYPQKSSKAILIKERFLGFVDTE---EMTGTHLHRTIKTY 700

Query: 316  -EKWGLNMEYCRGQAYIVSSGFSSKMKVVASRLLEKYPQAIYTLCSSCALNMWLAKSVP- 373
             ++ G++M+   GQAY  ++    K   +A+   ++ P+A+Y  C +  L++ + +    
Sbjct: 701  LQQIGVDMDKIHGQAYDSTTNLKIKFNKIAAEFKKEEPRALYIHCYAHFLDLSIIRFCKE 760

Query: 374  VMGVSVALGTIEEVCSFFHRSPQLLLELDNVISVLFQNSKERGKELKEICHSQWTGRHDA 433
            V  +  AL T+  + +    S ++L    N+   L QN   +    K I  S WT     
Sbjct: 761  VKELRSALKTLSSLFNTICMSGEMLANFRNIYR-LSQNKTCK----KHISQSCWTVHDRT 815

Query: 434  FEILVELLQALVLCLDGINSDTNIRWNNYIAGRAFVLCSAVSDFDFIVTIVVLKNVLSFT 493
               +++ L  ++  L+ I S ++   N   A     L + VS F+F+  +  L  VLS T
Sbjct: 816  LLSVIDSLPEIIETLEVIASHSS---NTSFADELSHLLTLVSKFEFVFCLKFLYRVLSVT 872

Query: 494  RAFGKNLQGQTSDVFFAAGSLTAVLHSLNEVMENIEVYHEFWFEEATNLATK-------- 545
                K LQ +T D+F  +  + A+L  L+   E  +VY +  ++    +  K        
Sbjct: 873  GILSKELQNKTIDIFSLSSKIEAILECLSS--ERNDVYFKTIWDGTEEICQKITCKGFKV 930

Query: 546  ----LDIQMKLPGKFRRAHQGNLESQLTSESYYKETLSVPTVEHIIQELKDIFSEQHLKA 601
                L  + K+       +  N+    ++E  YK  +    ++ I+Q LK  FSE     
Sbjct: 931  EKPSLQKRRKIQKSVDLGNSDNMFFPTSTEEQYKINIYYQGLDTILQNLKLCFSEFDYCK 990

Query: 602  LKCLSLVPSVMGQLKFNTSEEHHADMYRSDLPNPDTLSAELHCWRIKWKHRGKDIELPST 661
            +K +S +     +    T+ +H  + Y+ D      L    H  ++ +      I   S 
Sbjct: 991  IKQISELLFKWNEPLNETTAKHVQEFYKLDEDIIPELRFYRHYAKLNFVIDDSCINFVSL 1050

Query: 662  ----IYEALHLPDIKFFPNVYALLKVLCILPVMKVENERYENGRKRLKAYLRNTLTDQRS 717
                I   LH       P +  LL +    P+     E   +   RLK YL NT+  ++ 
Sbjct: 1051 GCLFIQHGLH----SNIPCLSKLLYIALSWPITSASTENSFSTLPRLKTYLCNTMGQEKL 1106

Query: 718  SNLALLNINFDIKHDL 733
            +  AL+ +  ++ + L
Sbjct: 1107 TGPALMAVEQELVNKL 1122


>gi|13899259 THAP domain containing, apoptosis associated protein 2
           [Homo sapiens]
          Length = 228

 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 39/106 (36%), Positives = 56/106 (52%), Gaps = 8/106 (7%)

Query: 1   MPNFCAAPNC-TRKSTQSDLAFFRFPRDPARCQKWVENCRRADLEDKTPDQLNKHYRLCA 59
           MP  CAA  C T  +   +++F RFP DP R ++WV   RR +          KH  LC+
Sbjct: 1   MPTNCAAAGCATTYNKHINISFHRFPLDPKRRKEWVRLVRRKNFVP------GKHTFLCS 54

Query: 60  KHFETSMICRTSPYRTVLRDNAIPTIFDLTSHLNNPHSRHRKRIKE 105
           KHFE S    T   R  L+ +A+PTIFD  +H+ +   + R  +K+
Sbjct: 55  KHFEASCFDLTGQTRR-LKMDAVPTIFDFCTHIKSMKLKSRNLLKK 99


>gi|194440668 THAP domain containing 5 isoform 1 [Homo sapiens]
          Length = 395

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 41/148 (27%), Positives = 65/148 (43%), Gaps = 12/148 (8%)

Query: 1   MPNFCAAPNCT----RKSTQSDLAFFRFP-RDPARCQKWVENCRRADLEDKTPDQLNKHY 55
           MP +CAA  C     R +    L+F+ FP  D  R +KW++N +R   +   P   +K+ 
Sbjct: 1   MPRYCAAICCKNRRGRNNKDRKLSFYPFPLHDKERLEKWLKNMKR---DSWVP---SKYQ 54

Query: 56  RLCAKHFETSMICRTSPYRTVLRDNAIPTIFDLTSHLNNPHSRHRKRIKELSEDEIRTLK 115
            LC+ HF    +      R  L+  A+PTIF L           +K  K+  EDE     
Sbjct: 55  FLCSDHFTPDSLDIRWGIR-YLKQTAVPTIFSLPEDNQGKDPSKKKSQKKNLEDEKEVCP 113

Query: 116 QKKIDETSEQEQKHKETNNSNAQNPSEE 143
           + K +E+    +  K   N++  +   E
Sbjct: 114 KAKSEESFVLNETKKNIVNTDVPHQHPE 141


>gi|56788351 THAP domain containing 7 isoform 2 [Homo sapiens]
          Length = 309

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 33/100 (33%), Positives = 51/100 (51%), Gaps = 9/100 (9%)

Query: 1  MPNFCAAPNC----TRKSTQSDLAFFRFPR-DPARCQKWVENCRRADLEDKTP-DQLNKH 54
          MP  C+A  C    TR++    ++F R P+ D  R   W+ NC+R D   +   D  +++
Sbjct: 1  MPRHCSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPASEY 60

Query: 55 YRLCAKHFETSM--ICRTSPYRTVLRDNAIPTIFDLTSHL 92
             C+KHFE     +   S Y   L++ A+PTIF+  S L
Sbjct: 61 IYFCSKHFEEDCFELVGISGYHR-LKEGAVPTIFESFSKL 99


>gi|56788349 THAP domain containing 7 isoform 1 [Homo sapiens]
          Length = 309

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 33/100 (33%), Positives = 51/100 (51%), Gaps = 9/100 (9%)

Query: 1  MPNFCAAPNC----TRKSTQSDLAFFRFPR-DPARCQKWVENCRRADLEDKTP-DQLNKH 54
          MP  C+A  C    TR++    ++F R P+ D  R   W+ NC+R D   +   D  +++
Sbjct: 1  MPRHCSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPASEY 60

Query: 55 YRLCAKHFETSM--ICRTSPYRTVLRDNAIPTIFDLTSHL 92
             C+KHFE     +   S Y   L++ A+PTIF+  S L
Sbjct: 61 IYFCSKHFEEDCFELVGISGYHR-LKEGAVPTIFESFSKL 99


>gi|31982895 THAP domain containing 4 [Homo sapiens]
          Length = 577

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 33/109 (30%), Positives = 56/109 (51%), Gaps = 11/109 (10%)

Query: 5   CAAPNCTRKSTQSD---LAFFRFP-RDPARCQKWVENCRRADLEDKTPDQLNKHYRLCAK 60
           CAA NC+ +  + +   ++F RFP +D  R  +W++  +R   ++ TP    K+  LC++
Sbjct: 5   CAAVNCSNRQGKGEKRAVSFHRFPLKDSKRLIQWLKAVQR---DNWTP---TKYSFLCSE 58

Query: 61  HF-ETSMICRTSPYRTVLRDNAIPTIFDLTSHLNNPHSRHRKRIKELSE 108
           HF + S   R      +L+  A+P+IF LT          R R K+ S+
Sbjct: 59  HFTKDSFSKRLEDQHRLLKPTAVPSIFHLTEKKRGAGGHGRTRRKDASK 107


>gi|46195755 SCAN domain containing 3 [Homo sapiens]
          Length = 1325

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 66/360 (18%), Positives = 138/360 (38%), Gaps = 34/360 (9%)

Query: 233  TQQRQMLEICESCIREETLREVRDSHFFSIITDDVVDIAGEEHLPVLVRFVDESHNLREE 292
            T  R++ E+    + ++ + +++ + +FS+  D+  DIA    L V VRF +   +++EE
Sbjct: 873  TIARRIQELAND-MEDQLIEQIKLAKYFSLQLDECRDIANMIILLVYVRF-EHDDDIKEE 930

Query: 293  FI--GFLPYEADAEILAVKFHTMITEKWGLNMEYCRGQAYIVSSGFSSKMKVVASRLLEK 350
            F     LP    +  L       I  K GL  ++C G     ++  + K   V +++ E 
Sbjct: 931  FFFSASLPTNTTSSELYEAVKNYIVNKCGLEFKFCVGVCSDGAASMTGKHSEVVTQIKEL 990

Query: 351  YPQAIYTLC----SSCALNMWLAKSVPVMGVSVALGTIEEVCSFFHRSPQLLLELDNVIS 406
             P+   T C     S A+    A+      ++  L  I ++ ++  +S  L   L    S
Sbjct: 991  APECKTTHCFIHRESLAMKKISAE------LNSVLNDIVKIVNYI-KSNSLNSRL---FS 1040

Query: 407  VLFQNSKERGKELKEICHSQWTGRHDAFEILVELLQALVLCLDGINSDTNIRWNNYIAGR 466
            +L  N +   K+L      +W  R      + E+   L++               ++ G+
Sbjct: 1041 LLCDNMEADHKQLLLHAEIRWLSRGKVLSRMFEIRNELLV---------------FLQGK 1085

Query: 467  AFVLCSAVSDFDFIVTIVVLKNVLSFTRAFGKNLQGQTSDVFFAAGSLTAVLHSLNEVME 526
              +      D ++   +  L ++ S       ++QG+ +  F  A  +      L     
Sbjct: 1086 KPMWSQLFKDVNWTARLAYLSDIFSIFNDLNASMQGKNATYFSMADKVEGQKQKLEAWKN 1145

Query: 527  NIEVYHEFWFEEATNLATKLDIQMKLPGKFRRAHQGNLESQLTSESYYKETLSVPTVEHI 586
             I       F   T +  ++   + +    R+    +L + L    +Y  +   P + ++
Sbjct: 1146 RISTDCYDMFHNLTTIINEVGNDLDI-AHLRKVISEHLTNLLECFEFYFPSKEDPRIGNL 1204


>gi|21389507 THAP domain containing 6 [Homo sapiens]
          Length = 222

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 1/92 (1%)

Query: 7   APNCTRKSTQSDLAFFRFPRDPARCQKWVENCRRADLEDKTPDQLNKHYRLCAKHFETSM 66
           A  C   S    L F  FP D    +KWV   +R D+      +  K   LC++HF+ + 
Sbjct: 11  ASRCLPNSKLKGLTFHVFPTDENIKRKWVLAMKRLDVNAAGIWEPKKGDVLCSRHFKKTD 70

Query: 67  ICRTSPYRTVLRDNAIPTIFDLTSHLNNPHSR 98
             R++P    L+   IP+IFD   HL     +
Sbjct: 71  FDRSAP-NIKLKPGVIPSIFDSPYHLQGKREK 101


>gi|40354197 THAP domain containing 11 [Homo sapiens]
          Length = 314

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 38/157 (24%), Positives = 64/157 (40%), Gaps = 13/157 (8%)

Query: 1   MPNF-CAAPNCTRKSTQSD-LAFFRFPRDPARCQKWVENCRRADLED-KTPDQLNKHYRL 57
           MP F C  P C   S +   L F+ FP+D    + W++N  RA +    +  Q    +RL
Sbjct: 1   MPGFTCCVPGCYNNSHRDKALHFYTFPKDAELRRLWLKNVSRAGVSGCFSTFQPTTGHRL 60

Query: 58  CAKHFETSMICRTSPYRTVLRDNAIPTIFDLTSHLNNPHSRHRKRIKELSEDEIRTLKQK 117
           C+ HF+     +T   R       +PTIF L   +N      R      +    +  +Q+
Sbjct: 61  CSVHFQGGR--KTYTVR-------VPTIFPLRG-VNERKVARRPAGAAAARRRQQQQQQQ 110

Query: 118 KIDETSEQEQKHKETNNSNAQNPSEEEGEGQDEDILP 154
           +  +  +Q+Q+ ++      Q  S      Q   + P
Sbjct: 111 QQQQQQQQQQQQQQQQQQQQQQSSPSASTAQTAQLQP 147


>gi|22749337 THAP domain containing 8 [Homo sapiens]
          Length = 274

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 29/92 (31%), Positives = 46/92 (50%), Gaps = 13/92 (14%)

Query: 1  MPNFCAAPNCTRK-----STQSDLAFFRFP-RDPARCQKWVENCRRADLEDKTPDQLNKH 54
          MP +C APNC+       +    ++F++FP +D  R Q W+++      E   P   + H
Sbjct: 1  MPKYCRAPNCSNTAGRLGADNRPVSFYKFPLKDGPRLQAWLQH---MGCEHWVP---SCH 54

Query: 55 YRLCAKHFETSMICRTSPYRTVLRDNAIPTIF 86
            LC++HF  S        R  LR +A+P+IF
Sbjct: 55 QHLCSEHFTPSCFQWRWGVR-YLRPDAVPSIF 85


>gi|8922446 THAP domain containing, apoptosis associated protein 1
          isoform 1 [Homo sapiens]
          Length = 213

 Score = 40.0 bits (92), Expect = 0.008
 Identities = 28/100 (28%), Positives = 47/100 (47%), Gaps = 13/100 (13%)

Query: 1  MPNFCAAPNC-TRKSTQSDLAFFRFPRD-PARCQKWVENCRRADLEDKTPDQLNKHYRLC 58
          M   C+A  C  R      ++F +FP   P+ C++W    RR + +        K+  +C
Sbjct: 1  MVQSCSAYGCKNRYDKDKPVSFHKFPLTRPSLCKEWEAAVRRKNFKP------TKYSSIC 54

Query: 59 AKHFETSMICRTSPYRTVLRDNAIPTIFDLTSHLNNPHSR 98
          ++HF      R    + +L++NA+PTIF  T     PH +
Sbjct: 55 SEHFTPDCFKRECNNK-LLKENAVPTIFLCT----EPHDK 89


>gi|94536788 THAP domain containing 9 [Homo sapiens]
          Length = 903

 Score = 39.7 bits (91), Expect = 0.011
 Identities = 25/89 (28%), Positives = 40/89 (44%), Gaps = 5/89 (5%)

Query: 1  MPNFCAAPNCTRKST----QSDLAFFRFPRDPARCQKWVENCRRADLEDKTPDQLNKHYR 56
          M   C+A  C+ + T    +  L+F +FP D  +  KW+    R D   K          
Sbjct: 1  MTRSCSAVGCSTRDTVLSRERGLSFHQFPTDTIQRSKWIRAVNRVDPRSKKIWIPGPGAI 60

Query: 57 LCAKHFETSMICRTSPYRTVLRDNAIPTI 85
          LC+KHF+ S    +   R  L+  A+P++
Sbjct: 61 LCSKHFQESDF-ESYGIRRKLKKGAVPSV 88


>gi|15149465 caldesmon 1 isoform 5 [Homo sapiens]
          Length = 532

 Score = 38.5 bits (88), Expect = 0.023
 Identities = 33/112 (29%), Positives = 46/112 (41%), Gaps = 5/112 (4%)

Query: 100 RKRIKELSEDEIRTLKQKKIDETSEQEQKHKETNNSNAQNPSEEEGEGQDEDILPLTLEE 159
           R+R  E   +E   LKQK+ +   E E+  K+          EE+   Q+E      L E
Sbjct: 279 RRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEE--ADRKLRE 336

Query: 160 KENKEYLKSLFE---ILILMGKQNIPLDGHEADEIPEGLFTPDNFQALLECR 208
           +E K  LK   E         +Q +P DG   D+ P   FTP      +E R
Sbjct: 337 EEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEER 388



 Score = 31.6 bits (70), Expect = 2.9
 Identities = 44/173 (25%), Positives = 71/173 (41%), Gaps = 17/173 (9%)

Query: 97  SRHRKRIKELSEDEIRTLKQKKID--ETSEQEQKHKETNNSNAQNPSEEE-GEGQDEDIL 153
           S  R+   E+ E E  T   +K D  +  E +++ KE      + P     GE Q +D  
Sbjct: 147 SESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQIKD-- 204

Query: 154 PLTLEEKENKEYLKSLFEI---LILMGKQNIPLDGHEADEI------PEGLFTPDNFQAL 204
               ++KE KE +KS  +       +  QN     H+          P G  + D  +A 
Sbjct: 205 EKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAE 264

Query: 205 LECRINSG---EEVLRKRFETTAVNTLFCSKTQQRQMLEICESCIREETLREV 254
              ++ +G   EE+ R+R ET +       + QQ   LE+ E   + E  R+V
Sbjct: 265 GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKV 317


>gi|15149463 caldesmon 1 isoform 4 [Homo sapiens]
          Length = 558

 Score = 38.5 bits (88), Expect = 0.023
 Identities = 33/112 (29%), Positives = 46/112 (41%), Gaps = 5/112 (4%)

Query: 100 RKRIKELSEDEIRTLKQKKIDETSEQEQKHKETNNSNAQNPSEEEGEGQDEDILPLTLEE 159
           R+R  E   +E   LKQK+ +   E E+  K+          EE+   Q+E      L E
Sbjct: 305 RRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEE--ADRKLRE 362

Query: 160 KENKEYLKSLFE---ILILMGKQNIPLDGHEADEIPEGLFTPDNFQALLECR 208
           +E K  LK   E         +Q +P DG   D+ P   FTP      +E R
Sbjct: 363 EEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEER 414



 Score = 32.0 bits (71), Expect = 2.2
 Identities = 44/168 (26%), Positives = 67/168 (39%), Gaps = 28/168 (16%)

Query: 115 KQKKIDETSEQEQKHKETNNSNAQNPSEEEG-------EGQDEDILPLTLEE-------- 159
           + KK D+  E+E++ K    S  +N  EE+G       E   ED      EE        
Sbjct: 176 ENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKK 235

Query: 160 -KENKEYLKSLFEI---LILMGKQNIPLDGHEADEI------PEGLFTPDNFQALLECRI 209
            KE KE +KS  +       +  QN     H+          P G  + D  +A    ++
Sbjct: 236 DKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQV 295

Query: 210 NSG---EEVLRKRFETTAVNTLFCSKTQQRQMLEICESCIREETLREV 254
            +G   EE+ R+R ET +       + QQ   LE+ E   + E  R+V
Sbjct: 296 EAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKV 343


>gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]
          Length = 564

 Score = 38.5 bits (88), Expect = 0.023
 Identities = 33/112 (29%), Positives = 46/112 (41%), Gaps = 5/112 (4%)

Query: 100 RKRIKELSEDEIRTLKQKKIDETSEQEQKHKETNNSNAQNPSEEEGEGQDEDILPLTLEE 159
           R+R  E   +E   LKQK+ +   E E+  K+          EE+   Q+E      L E
Sbjct: 311 RRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEE--ADRKLRE 368

Query: 160 KENKEYLKSLFE---ILILMGKQNIPLDGHEADEIPEGLFTPDNFQALLECR 208
           +E K  LK   E         +Q +P DG   D+ P   FTP      +E R
Sbjct: 369 EEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEER 420



 Score = 32.0 bits (71), Expect = 2.2
 Identities = 44/168 (26%), Positives = 67/168 (39%), Gaps = 28/168 (16%)

Query: 115 KQKKIDETSEQEQKHKETNNSNAQNPSEEEG-------EGQDEDILPLTLEE-------- 159
           + KK D+  E+E++ K    S  +N  EE+G       E   ED      EE        
Sbjct: 182 ENKKEDKEKEEEEEEKPKRGSIGENQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKK 241

Query: 160 -KENKEYLKSLFEI---LILMGKQNIPLDGHEADEI------PEGLFTPDNFQALLECRI 209
            KE KE +KS  +       +  QN     H+          P G  + D  +A    ++
Sbjct: 242 DKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQV 301

Query: 210 NSG---EEVLRKRFETTAVNTLFCSKTQQRQMLEICESCIREETLREV 254
            +G   EE+ R+R ET +       + QQ   LE+ E   + E  R+V
Sbjct: 302 EAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKV 349


>gi|4826657 caldesmon 1 isoform 2 [Homo sapiens]
          Length = 538

 Score = 38.5 bits (88), Expect = 0.023
 Identities = 33/112 (29%), Positives = 46/112 (41%), Gaps = 5/112 (4%)

Query: 100 RKRIKELSEDEIRTLKQKKIDETSEQEQKHKETNNSNAQNPSEEEGEGQDEDILPLTLEE 159
           R+R  E   +E   LKQK+ +   E E+  K+          EE+   Q+E      L E
Sbjct: 285 RRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEE--ADRKLRE 342

Query: 160 KENKEYLKSLFE---ILILMGKQNIPLDGHEADEIPEGLFTPDNFQALLECR 208
           +E K  LK   E         +Q +P DG   D+ P   FTP      +E R
Sbjct: 343 EEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEER 394



 Score = 31.6 bits (70), Expect = 2.9
 Identities = 44/173 (25%), Positives = 71/173 (41%), Gaps = 17/173 (9%)

Query: 97  SRHRKRIKELSEDEIRTLKQKKID--ETSEQEQKHKETNNSNAQNPSEEE-GEGQDEDIL 153
           S  R+   E+ E E  T   +K D  +  E +++ KE      + P     GE Q +D  
Sbjct: 153 SESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQIKD-- 210

Query: 154 PLTLEEKENKEYLKSLFEI---LILMGKQNIPLDGHEADEI------PEGLFTPDNFQAL 204
               ++KE KE +KS  +       +  QN     H+          P G  + D  +A 
Sbjct: 211 EKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAE 270

Query: 205 LECRINSG---EEVLRKRFETTAVNTLFCSKTQQRQMLEICESCIREETLREV 254
              ++ +G   EE+ R+R ET +       + QQ   LE+ E   + E  R+V
Sbjct: 271 GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKV 323


>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
          Length = 793

 Score = 38.5 bits (88), Expect = 0.023
 Identities = 33/112 (29%), Positives = 46/112 (41%), Gaps = 5/112 (4%)

Query: 100 RKRIKELSEDEIRTLKQKKIDETSEQEQKHKETNNSNAQNPSEEEGEGQDEDILPLTLEE 159
           R+R  E   +E   LKQK+ +   E E+  K+          EE+   Q+E      L E
Sbjct: 540 RRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEE--ADRKLRE 597

Query: 160 KENKEYLKSLFE---ILILMGKQNIPLDGHEADEIPEGLFTPDNFQALLECR 208
           +E K  LK   E         +Q +P DG   D+ P   FTP      +E R
Sbjct: 598 EEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEER 649


>gi|33356128 NMDA receptor regulated 1-like protein isoform 1 [Homo
           sapiens]
          Length = 864

 Score = 38.1 bits (87), Expect = 0.031
 Identities = 19/70 (27%), Positives = 37/70 (52%), Gaps = 1/70 (1%)

Query: 94  NPHSRHRKRIKELSEDEIRTLKQKKIDETSEQ-EQKHKETNNSNAQNPSEEEGEGQDEDI 152
           N  +   K +K++   + R  K+ K++E  +  E++ ++ N    ++  EEE  G  E++
Sbjct: 583 NSENLSAKELKKMLSKQRRAQKKAKLEEERKHAERERQQKNQKKKRDEEEEEASGLKEEL 642

Query: 153 LPLTLEEKEN 162
           +P  LE  EN
Sbjct: 643 IPEKLERVEN 652


>gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo
           sapiens]
          Length = 1369

 Score = 37.7 bits (86), Expect = 0.040
 Identities = 28/89 (31%), Positives = 45/89 (50%), Gaps = 12/89 (13%)

Query: 118 KIDETSEQEQKHKETNNSNAQNPSEE-EGEGQDEDILPLTLEEK--ENKEYLKSLFEIL- 173
           K+ +  +Q+Q+H E    N+++P E  E    DED   L+LE    E+ E +++LF  L 
Sbjct: 498 KLKQQQQQQQQHSENKRENSEDPEESWENLVSDEDFSALSLESANVEDLEPVRNLFRKLQ 557

Query: 174 -------ILMGKQNIPLDGHEADEIPEGL 195
                  +L  +Q +P+  H  D I E L
Sbjct: 558 STPKYQKLLKERQQLPVFKHR-DSIVETL 585


>gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]
          Length = 569

 Score = 37.0 bits (84), Expect = 0.068
 Identities = 17/55 (30%), Positives = 34/55 (61%), Gaps = 3/55 (5%)

Query: 100 RKRIKELSEDEIRT---LKQKKIDETSEQEQKHKETNNSNAQNPSEEEGEGQDED 151
           ++ +KE  E+E++    +K+K+  E  E+E+  ++      +N +EEEGE +DE+
Sbjct: 370 QQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEE 424


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
           sapiens]
          Length = 1152

 Score = 36.2 bits (82), Expect = 0.12
 Identities = 24/62 (38%), Positives = 33/62 (53%), Gaps = 4/62 (6%)

Query: 104 KELSEDEIRTLKQKKIDETSEQEQKH-KETNNSNAQNPSEEEGEGQDEDILPLTLEEKEN 162
           KEL+E E    +  +  E  E+EQ H KE N    +   EE GEG++E+      EE+E 
Sbjct: 694 KELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEE---GDREEEEE 750

Query: 163 KE 164
           KE
Sbjct: 751 KE 752


>gi|28460688 taxilin [Homo sapiens]
          Length = 546

 Score = 35.8 bits (81), Expect = 0.15
 Identities = 49/212 (23%), Positives = 84/212 (39%), Gaps = 22/212 (10%)

Query: 47  TPDQLNKHYRLCAKHFETSMICRTSPYRTVLRDNAIPTIFDLTSHLNNPHSRH---RKRI 103
           TP++  K   LC K+ E     R S  +  L       +     HL   HS+    R ++
Sbjct: 184 TPEE--KLAALCKKYAELLEEHRNSQKQMKLLQKKQSQLVQEKDHLRGEHSKAVLARSKL 241

Query: 104 KELSED---EIRTLKQKKIDETSEQEQKHKETNN--SNAQNPSEEEGEGQDEDILPLTLE 158
           + L  +     R+LK++ +    E+E+K KE  +      N  + + E  +E    L  E
Sbjct: 242 ESLCRELQRHNRSLKEEGVQRAREEEEKRKEVTSHFQVTLNDIQLQMEQHNERNSKLRQE 301

Query: 159 EKENKEYLKSLFEILILMGKQNIPLDGHEADEIPEGLFTPDNFQALLECRINSGEEVLRK 218
             E  E LK L E   L             + I +     D  Q L++ ++   +E+L++
Sbjct: 302 NMELAERLKKLIEQYEL-----------REEHIDKVFKHKDLQQQLVDAKLQQAQEMLKE 350

Query: 219 RFETTAVNTLFCSKTQQRQMLEICESCIREET 250
             E       F  K +  +   +CE   ++ET
Sbjct: 351 AEERHQREKDFLLK-EAVESQRMCELMKQQET 381


>gi|8923271 coiled-coil domain containing 49 [Homo sapiens]
          Length = 425

 Score = 35.8 bits (81), Expect = 0.15
 Identities = 19/53 (35%), Positives = 33/53 (62%), Gaps = 2/53 (3%)

Query: 92  LNNPHSRHRKRIKELSEDEIRTLKQKKIDETSEQEQKHKETNNSNAQNPSEEE 144
           LNNP     K+IKEL +  +   ++KK  E  ++ +KHK  ++S+ ++ SE+E
Sbjct: 154 LNNPVKM--KKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSSSEDE 204


>gi|197276647 leucine rich repeat (in FLII) interacting protein 2
           isoform 3 [Homo sapiens]
          Length = 424

 Score = 35.4 bits (80), Expect = 0.20
 Identities = 38/142 (26%), Positives = 59/142 (41%), Gaps = 31/142 (21%)

Query: 63  ETSMICRTSPYRTVLRDNAIPTIFDLTSHLNNPHSRHRKRIKELSEDEIRTLKQKKIDET 122
           +TS +       + LRD     I+DL   + +   R+ + +KEL E              
Sbjct: 98  DTSSLIDPDTSLSELRD-----IYDLKDQIQDVEGRYMQGLKELKES------------L 140

Query: 123 SEQEQKHKETNNSNAQNPSEEEGEGQDEDILPLTLEE---------KENKEYLKSLFEIL 173
           SE E+K+K+   SNAQ  +E+       D L   +EE         +EN+E  K L    
Sbjct: 141 SEVEEKYKKAMVSNAQLDNEKNNLIYQVDTLKDVIEEQEEQMAEFYRENEEKSKELER-- 198

Query: 174 ILMGKQNIPLDGHEADEIPEGL 195
               K    +  H+ +E+ EGL
Sbjct: 199 ---QKHMCSVLQHKMEELKEGL 217


>gi|5453726 leucine rich repeat (in FLII) interacting protein 2
           isoform 1 [Homo sapiens]
          Length = 721

 Score = 35.4 bits (80), Expect = 0.20
 Identities = 38/142 (26%), Positives = 59/142 (41%), Gaps = 31/142 (21%)

Query: 63  ETSMICRTSPYRTVLRDNAIPTIFDLTSHLNNPHSRHRKRIKELSEDEIRTLKQKKIDET 122
           +TS +       + LRD     I+DL   + +   R+ + +KEL E              
Sbjct: 330 DTSSLIDPDTSLSELRD-----IYDLKDQIQDVEGRYMQGLKELKES------------L 372

Query: 123 SEQEQKHKETNNSNAQNPSEEEGEGQDEDILPLTLEE---------KENKEYLKSLFEIL 173
           SE E+K+K+   SNAQ  +E+       D L   +EE         +EN+E  K L    
Sbjct: 373 SEVEEKYKKAMVSNAQLDNEKNNLIYQVDTLKDVIEEQEEQMAEFYRENEEKSKELER-- 430

Query: 174 ILMGKQNIPLDGHEADEIPEGL 195
               K    +  H+ +E+ EGL
Sbjct: 431 ---QKHMCSVLQHKMEELKEGL 449


>gi|124249396 coiled-coil domain containing 30 [Homo sapiens]
          Length = 783

 Score = 35.0 bits (79), Expect = 0.26
 Identities = 45/205 (21%), Positives = 82/205 (40%), Gaps = 15/205 (7%)

Query: 97  SRHRKRIKELSEDEIRTLKQKKIDETSEQEQKHKETNNSNAQNPSEEEGEGQDEDILPLT 156
           S+ R+R K+L+       K  K++    Q+ K +     N  +    E E +D  ++   
Sbjct: 14  SKEREREKQLASGLDTAEKALKVESEELQKSKSELICLYNEVHNLPGESESKDHFLIACD 73

Query: 157 LEEKENKEYLKSLFEILILMGKQN-IPLDGHEADEIPEGLFTPDNFQALLECR-INSGEE 214
           L ++EN E    + ++     + N   L G  A   P  L T +N      C+   S E 
Sbjct: 74  LLQRENSELETKVLKLSQEFAQLNHFTLGGKTA---PSNLITSEN-----TCKDPESNEP 125

Query: 215 VLRKRFETTAVNT-LFCSKTQQRQMLEICESCIREETLREVRDSHFFSIITDDVVDIAGE 273
           +L    ++    T   C K  +R+  EI E  ++E +          S    D+ D   E
Sbjct: 126 ILETEIQSRKEETEELCPKLGERKQKEIPEESVKEGSFPREGQKEEGSQQNRDMKDEEKE 185

Query: 274 EHLPV----LVRFVDESHNLREEFI 294
           + L +    +VR  +E  ++ +  +
Sbjct: 186 QQLTMKPEEIVRLREELSHINQSLL 210


>gi|15559209 interleukin 33 [Homo sapiens]
          Length = 270

 Score = 34.7 bits (78), Expect = 0.34
 Identities = 33/129 (25%), Positives = 60/129 (46%), Gaps = 12/129 (9%)

Query: 36  ENCRRADLEDKTPDQLNKHYRLCAKHFETSMIC------RTSPYRTVLRDNAIPTIFDLT 89
           E  +R  L  KT  +  +H  L A   ++++ C          Y   L D++I  I  +T
Sbjct: 63  ETTKRPSL--KTGRKHKRHLVLAACQQQSTVECFAFGISGVQKYTRALHDSSITGISPIT 120

Query: 90  SHLNNPHSRHRKRIKELSEDEIRTLKQKKIDETSEQEQKHKET-NNSNAQNPSEEEGEGQ 148
            +L +  + + + I    EDE   +    +++  + E+K K   +   +Q+PS E G+G 
Sbjct: 121 EYLASLSTYNDQSITFALEDESYEIY---VEDLKKDEKKDKVLLSYYESQHPSNESGDGV 177

Query: 149 DEDILPLTL 157
           D  +L +TL
Sbjct: 178 DGKMLMVTL 186


>gi|149773449 zinc finger protein 862 [Homo sapiens]
          Length = 1169

 Score = 34.7 bits (78), Expect = 0.34
 Identities = 49/219 (22%), Positives = 97/219 (44%), Gaps = 27/219 (12%)

Query: 209 INSGEEVLRKRFET-TAVNTLFCSKTQQRQMLEICESCIREETLREVRDSHFFSIITDDV 267
           +N  E++L+    T T +   + ++T   Q ++     ++ E L +VR+S   S++ D  
Sbjct: 572 LNDFEKILQLLQSTGTVILGKYRNRTACTQFIKYISETLKREILEDVRNSPCVSVLLDSS 631

Query: 268 VDIAGEEHLPVLVRFVDESHNLREEFIGFLPYEADAEILAVKFHTMITEKWGLNMEYCRG 327
            D + +  + + +R+  +   ++E +I   P    +E     F T+++    L++ + R 
Sbjct: 632 TDASEQACVGIYIRYFKQM-EVKESYITLAPLY--SETADGYFETIVSALDELDIPF-RK 687

Query: 328 QAYIVSSGF-SSKMKVVASRLLEKYPQAIYTLCSSCALNMWLAKSVPVMGVSVALG-TIE 385
             ++V  G   S M      L+EK+ + I  L             +PV  V+  L   + 
Sbjct: 688 PGWVVGLGTDGSAMLSCRGGLVEKFQEVIPQL-------------LPVHCVAHRLHLAVV 734

Query: 386 EVCSFFHRSPQLLLELDNVISVLF---QNSKERGKELKE 421
           + C     S  L+ + D  I  +F   Q+S +R  EL+E
Sbjct: 735 DACG----SIDLVKKCDRHIRTVFKFYQSSNKRLNELQE 769


>gi|19924131 RAD50 homolog isoform 2 [Homo sapiens]
          Length = 1173

 Score = 34.3 bits (77), Expect = 0.44
 Identities = 43/190 (22%), Positives = 81/190 (42%), Gaps = 40/190 (21%)

Query: 100 RKRIKELSEDEIRTLKQKKIDETSEQEQKHKETNNSNAQNPSEEEGEGQDEDILPL---- 155
           + R+KE+  +  + +K     +  +  +K  E +NS  +   E+  +G DE +  L    
Sbjct: 113 KNRLKEIEHNLSKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKVFQGTDEQLNDLYHNH 172

Query: 156 --TLEEKENK-----EYLKSL-----------FEILILMGKQNIPLDGHE-----ADEIP 192
             T+ EKE K       L+ L            E+L+  G+  +  D H+      D + 
Sbjct: 173 QRTVREKERKLVDCHRELEKLNKESRLLNQEKSELLVEQGRLQLQADRHQEHIRARDSLI 232

Query: 193 EGLFTP---DNFQ--ALLECRINSGEEVLRKRFETTAVNTLFCSKTQQRQMLEICE-SCI 246
           + L T    D F+     E +I +  +++R+R E  A       KT  + M +  E   +
Sbjct: 233 QSLATQLELDGFERGPFSERQIKNFHKLVRERQEGEA-------KTANQLMNDFAEKETL 285

Query: 247 REETLREVRD 256
           +++ + E+RD
Sbjct: 286 KQKQIDEIRD 295


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,369,356
Number of Sequences: 37866
Number of extensions: 1282096
Number of successful extensions: 7009
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 114
Number of HSP's that attempted gapping in prelim test: 6269
Number of HSP's gapped (non-prelim): 636
length of query: 761
length of database: 18,247,518
effective HSP length: 110
effective length of query: 651
effective length of database: 14,082,258
effective search space: 9167549958
effective search space used: 9167549958
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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