Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 194353992

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194353992 amyloid beta A4 precursor protein-binding, family
A, member 2 isoform b [Homo sapiens]
         (737 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194353992 amyloid beta A4 precursor protein-binding, family A...  1499   0.0  
gi|22035550 amyloid beta A4 precursor protein-binding, family A,...  1490   0.0  
gi|22035548 amyloid beta A4 precursor protein-binding, family A,...   703   0.0  
gi|11342678 amyloid beta (A4) precursor protein-binding, family ...   488   e-138
gi|55749523 syntenin isoform 3 [Homo sapiens]                          61   4e-09
gi|55749515 syntenin isoform 3 [Homo sapiens]                          61   4e-09
gi|55749504 syntenin isoform 2 [Homo sapiens]                          61   4e-09
gi|55749490 syntenin isoform 1 [Homo sapiens]                          61   4e-09
gi|56243522 syntenin isoform 1 [Homo sapiens]                          61   4e-09
gi|134152672 syndecan binding protein 2 isoform a [Homo sapiens]       58   3e-08
gi|38016916 syndecan binding protein 2 isoform b [Homo sapiens]        58   3e-08
gi|112382257 InaD-like [Homo sapiens]                                  55   2e-07
gi|148746189 multiple PDZ domain protein [Homo sapiens]                55   2e-07
gi|4557529 post-synaptic density protein 95 isoform 1 [Homo sapi...    53   9e-07
gi|192447426 post-synaptic density protein 95 isoform 2 [Homo sa...    53   9e-07
gi|223890252 glutamate receptor interacting protein 1 [Homo sapi...    52   3e-06
gi|119943106 synapse-associated protein 102 isoform a [Homo sapi...    52   3e-06
gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]           50   6e-06
gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]           50   6e-06
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              50   6e-06
gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]                      50   8e-06
gi|218156338 chapsyn-110 isoform 1 [Homo sapiens]                      50   8e-06
gi|91199538 chapsyn-110 isoform 2 [Homo sapiens]                       50   8e-06
gi|38570142 membrane protein, palmitoylated 5 [Homo sapiens]           49   1e-05
gi|169212742 PREDICTED: similar to hCG1654128 [Homo sapiens]           47   5e-05
gi|222446609 rai-like protein [Homo sapiens]                           46   1e-04
gi|10835173 nitric oxide synthase 1, neuronal [Homo sapiens]           46   1e-04
gi|169213065 PREDICTED: similar to hCG1654128 [Homo sapiens]           46   1e-04
gi|122937249 glutamate receptor interacting protein 2 [Homo sapi...    46   1e-04
gi|45827729 scribble isoform b [Homo sapiens]                          46   1e-04

>gi|194353992 amyloid beta A4 precursor protein-binding, family A,
           member 2 isoform b [Homo sapiens]
          Length = 737

 Score = 1499 bits (3881), Expect = 0.0
 Identities = 737/737 (100%), Positives = 737/737 (100%)

Query: 1   MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE 60
           MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE
Sbjct: 1   MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE 60

Query: 61  QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE 120
           QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE
Sbjct: 61  QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE 120

Query: 121 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ 180
           YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ
Sbjct: 121 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ 180

Query: 181 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT 240
           EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT
Sbjct: 181 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT 240

Query: 241 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF 300
           SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF
Sbjct: 241 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF 300

Query: 301 KPKTRTPEERLKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP 360
           KPKTRTPEERLKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP
Sbjct: 301 KPKTRTPEERLKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP 360

Query: 361 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKNSEGDAQTLTEVDLF 420
           CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKNSEGDAQTLTEVDLF
Sbjct: 361 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKNSEGDAQTLTEVDLF 420

Query: 421 ISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSASQDCIETTPGAQE 480
           ISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSASQDCIETTPGAQE
Sbjct: 421 ISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSASQDCIETTPGAQE 480

Query: 481 GKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQKEYSDIINTQEM 540
           GKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQKEYSDIINTQEM
Sbjct: 481 GKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQKEYSDIINTQEM 540

Query: 541 YNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSGKL 600
           YNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSGKL
Sbjct: 541 YNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSGKL 600

Query: 601 SIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKRPDLKYQLG 660
           SIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKRPDLKYQLG
Sbjct: 601 SIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKRPDLKYQLG 660

Query: 661 FSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMKTM 720
           FSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMKTM
Sbjct: 661 FSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMKTM 720

Query: 721 PAAMFRLLTGQETPLYI 737
           PAAMFRLLTGQETPLYI
Sbjct: 721 PAAMFRLLTGQETPLYI 737


>gi|22035550 amyloid beta A4 precursor protein-binding, family A,
           member 2 isoform a [Homo sapiens]
          Length = 749

 Score = 1490 bits (3858), Expect = 0.0
 Identities = 737/749 (98%), Positives = 737/749 (98%), Gaps = 12/749 (1%)

Query: 1   MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE 60
           MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE
Sbjct: 1   MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE 60

Query: 61  QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE 120
           QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE
Sbjct: 61  QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE 120

Query: 121 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ 180
           YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ
Sbjct: 121 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ 180

Query: 181 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT 240
           EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT
Sbjct: 181 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT 240

Query: 241 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF 300
           SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF
Sbjct: 241 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF 300

Query: 301 KPKTRTPEERLKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP 360
           KPKTRTPEERLKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP
Sbjct: 301 KPKTRTPEERLKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP 360

Query: 361 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVK------------NSE 408
           CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVK            NSE
Sbjct: 361 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSE 420

Query: 409 GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS 468
           GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS
Sbjct: 421 GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS 480

Query: 469 QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ 528
           QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ
Sbjct: 481 QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ 540

Query: 529 KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM 588
           KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM
Sbjct: 541 KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM 600

Query: 589 MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV 648
           MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV
Sbjct: 601 MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV 660

Query: 649 LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL 708
           LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL
Sbjct: 661 LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL 720

Query: 709 SNSVGEIHMKTMPAAMFRLLTGQETPLYI 737
           SNSVGEIHMKTMPAAMFRLLTGQETPLYI
Sbjct: 721 SNSVGEIHMKTMPAAMFRLLTGQETPLYI 749


>gi|22035548 amyloid beta A4 precursor protein-binding, family A,
           member 1 [Homo sapiens]
          Length = 837

 Score =  703 bits (1815), Expect = 0.0
 Identities = 426/813 (52%), Positives = 513/813 (63%), Gaps = 111/813 (13%)

Query: 28  EPESEDMELPLE----GYVPEGLELAALRPESPAPEEQ--ECHNHSPDGDSSSDYVNNTS 81
           E E E  + P +    G    G  L  LR +    EE+  EC   S   +S      +T+
Sbjct: 33  EVEEEQQQPPQQQHYVGRHQRGRALEDLRAQLGQEEEERGECLARSASTESGFHNHTDTA 92

Query: 82  E-------EEDYD-EGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEEYLAHSA------- 126
           E        + YD E   + E+   Y ++Y PE + Y E  +    E     A       
Sbjct: 93  EGDVIAAARDGYDAERAQDPEDESAYAVQYRPEAEEYTEQAEAEHAEATHRRALPNHLHF 152

Query: 127 HPVDTDECQEAV--------------------EEWTDSAGPHPHGHEAEGSQDYPDGQ-- 164
           H ++ +E   A                     E + D  G   H +E  G     D +  
Sbjct: 153 HSLEHEEAMNAAYSGYVYTHRLFHRGEDEPYSEPYADYGGLQEHVYEEIGDAPELDARDG 212

Query: 165 LPIPEDEPSVLEAHDQEEDG----HYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLE 220
           L + E E     A+ QE  G    HY    +G  D   +EA      +PY       D  
Sbjct: 213 LRLYEQERDEAAAYRQEALGARLHHYDERSDGESDSPEKEAE----FAPYPRM----DSY 264

Query: 221 DQEEDIDQIVAEIKMSLSMTSITSASEASPEHGPE----PGPEDSVEACPPIKASC---- 272
           +QEEDIDQIVAE+K S+S  S+  A+E  PE   +    P P       P ++A      
Sbjct: 265 EQEEDIDQIVAEVKQSMSSQSLDKAAEDMPEAEQDLERPPTPAGGRPDSPGLQAPAGQQR 324

Query: 273 --------------SPSRHEARPKSLNLLPEA---------KHPGDPQRGFKP------- 302
                         S  + +A   ++  + EA         + P  P    +P       
Sbjct: 325 AVGPAGGGEAGQRYSKEKRDAISLAIKDIKEAIEEVKTRTIRSPYTPDEPKEPIWVMRQD 384

Query: 303 --KTRTPEERLKWPHEQVCNGLEQPRKQQRSDLN----GPVDNNNIPETKK-VASFPSFV 355
              TR  +++     +    G   P   + S  +     PV+ +   E++K +ASFP++V
Sbjct: 385 ISPTRDCDDQRPMDGDSPSPGSSSPLGAESSSTSLHPSDPVEASTNKESRKSLASFPTYV 444

Query: 356 AVPGPCEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKNS-------- 407
            VPGPC+PEDLIDGIIFAANYLGSTQLLS++ PSKN+RMMQAQEAVSR+K +        
Sbjct: 445 EVPGPCDPEDLIDGIIFAANYLGSTQLLSDKTPSKNVRMMQAQEAVSRIKMAQKLAKSRK 504

Query: 408 ---EGDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMP 464
              EG++Q +TEVDLFISTQRIKVLNADTQETMMDH LRTISYIADIGNIVVLMARRRMP
Sbjct: 505 KAPEGESQPMTEVDLFISTQRIKVLNADTQETMMDHPLRTISYIADIGNIVVLMARRRMP 564

Query: 465 RSASQDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPE 524
           RS SQ+ +E +  +Q+GK+QYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPE
Sbjct: 565 RSNSQENVEASHPSQDGKRQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPE 624

Query: 525 DLSQKEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVI 584
           DLSQKEYSD++NTQ+MYNDDLIHFS SENCK++ +EK KGEILGVV+VESGWGSILPTVI
Sbjct: 625 DLSQKEYSDLLNTQDMYNDDLIHFSKSENCKDVFIEKQKGEILGVVIVESGWGSILPTVI 684

Query: 585 LANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPP 644
           +ANMM+GGPA +SGKL+IGDQIMSINGTSLVGLPL+TCQ IIKGLKNQ++VKLNIV CPP
Sbjct: 685 IANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLPLSTCQSIIKGLKNQSRVKLNIVRCPP 744

Query: 645 VTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKI 704
           VTTVLI+RPDL+YQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVAT HEKI
Sbjct: 745 VTTVLIRRPDLRYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATPHEKI 804

Query: 705 VQALSNSVGEIHMKTMPAAMFRLLTGQETPLYI 737
           V  LSN+VGEIHMKTMPAAM+RLLT QE P+YI
Sbjct: 805 VHILSNAVGEIHMKTMPAAMYRLLTAQEQPVYI 837


>gi|11342678 amyloid beta (A4) precursor protein-binding, family A,
           member 3 [Homo sapiens]
          Length = 575

 Score =  488 bits (1256), Expect = e-138
 Identities = 246/396 (62%), Positives = 310/396 (78%), Gaps = 15/396 (3%)

Query: 343 PETKKVASFPSFVAVPGPCEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVS 402
           PET  +AS+P+   VPGPC+ EDL+DG+IF A YLGSTQL+SERNP  + RM QA+EA+ 
Sbjct: 194 PET--LASYPAPQEVPGPCDHEDLLDGVIFGARYLGSTQLVSERNPPTSTRMAQAREAMD 251

Query: 403 RVKNSEGDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRR 462
           RVK  +G+ Q +TEVDLF+ST+RIKVL AD+QE MMDHAL TISY ADIG ++VLMARRR
Sbjct: 252 RVKAPDGETQPMTEVDLFVSTKRIKVLTADSQEAMMDHALHTISYTADIGCVLVLMARRR 311

Query: 463 MPRS-ASQDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGI 521
           + R  A QD          G++ YKM+CHVF +EDAQLIAQ+IGQAF+ AY +FLR +GI
Sbjct: 312 LARRPAPQD---------HGRRLYKMLCHVFYAEDAQLIAQAIGQAFAAAYSQFLRESGI 362

Query: 522 NPEDLSQKEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILP 581
           +P   SQ           ++N DL HFSNS+NC+E+ LEK +GE LGV +VESGWGS+LP
Sbjct: 363 DP---SQVGVHPSPGACHLHNGDLDHFSNSDNCREVHLEKRRGEGLGVALVESGWGSLLP 419

Query: 582 TVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVS 641
           T ++AN+++GGPA RSG LSIGD++ +INGTSLVGLPLA CQ  ++  K+QT V L+IV 
Sbjct: 420 TAVIANLLHGGPAERSGALSIGDRLTAINGTSLVGLPLAACQAAVRETKSQTSVTLSIVH 479

Query: 642 CPPVTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAH 701
           CPPVTT +I RP  + QLGF V++GIICSL+RGGIAERGG+RVGHRIIEINGQSVVAT H
Sbjct: 480 CPPVTTAIIHRPHAREQLGFCVEDGIICSLLRGGIAERGGIRVGHRIIEINGQSVVATPH 539

Query: 702 EKIVQALSNSVGEIHMKTMPAAMFRLLTGQETPLYI 737
            +I++ L+ + GE+H+KTMPAA +RLLTGQE P+Y+
Sbjct: 540 ARIIELLTEAYGEVHIKTMPAATYRLLTGQEQPVYL 575


>gi|55749523 syntenin isoform 3 [Homo sapiens]
          Length = 297

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 42/142 (29%), Positives = 69/142 (48%), Gaps = 3/142 (2%)

Query: 593 PAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKR 652
           PA+  G L  GDQ++ ING +  G        ++K    + ++ + I   P   T+ + +
Sbjct: 145 PASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGE-KITMTIRDRPFERTITMHK 202

Query: 653 PDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSV 712
            D    +GF  +NG I S+++   A R G+   H I EINGQ+V+     +I   LS S 
Sbjct: 203 -DSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADILSTSG 261

Query: 713 GEIHMKTMPAAMFRLLTGQETP 734
             + +  MPA +F  +  +  P
Sbjct: 262 TVVTITIMPAFIFEHIIKRMAP 283


>gi|55749515 syntenin isoform 3 [Homo sapiens]
          Length = 297

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 42/142 (29%), Positives = 69/142 (48%), Gaps = 3/142 (2%)

Query: 593 PAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKR 652
           PA+  G L  GDQ++ ING +  G        ++K    + ++ + I   P   T+ + +
Sbjct: 145 PASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGE-KITMTIRDRPFERTITMHK 202

Query: 653 PDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSV 712
            D    +GF  +NG I S+++   A R G+   H I EINGQ+V+     +I   LS S 
Sbjct: 203 -DSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADILSTSG 261

Query: 713 GEIHMKTMPAAMFRLLTGQETP 734
             + +  MPA +F  +  +  P
Sbjct: 262 TVVTITIMPAFIFEHIIKRMAP 283


>gi|55749504 syntenin isoform 2 [Homo sapiens]
          Length = 292

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 42/142 (29%), Positives = 69/142 (48%), Gaps = 3/142 (2%)

Query: 593 PAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKR 652
           PA+  G L  GDQ++ ING +  G        ++K    + ++ + I   P   T+ + +
Sbjct: 140 PASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGE-KITMTIRDRPFERTITMHK 197

Query: 653 PDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSV 712
            D    +GF  +NG I S+++   A R G+   H I EINGQ+V+     +I   LS S 
Sbjct: 198 -DSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADILSTSG 256

Query: 713 GEIHMKTMPAAMFRLLTGQETP 734
             + +  MPA +F  +  +  P
Sbjct: 257 TVVTITIMPAFIFEHIIKRMAP 278


>gi|55749490 syntenin isoform 1 [Homo sapiens]
          Length = 298

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 42/142 (29%), Positives = 69/142 (48%), Gaps = 3/142 (2%)

Query: 593 PAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKR 652
           PA+  G L  GDQ++ ING +  G        ++K    + ++ + I   P   T+ + +
Sbjct: 146 PASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGE-KITMTIRDRPFERTITMHK 203

Query: 653 PDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSV 712
            D    +GF  +NG I S+++   A R G+   H I EINGQ+V+     +I   LS S 
Sbjct: 204 -DSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADILSTSG 262

Query: 713 GEIHMKTMPAAMFRLLTGQETP 734
             + +  MPA +F  +  +  P
Sbjct: 263 TVVTITIMPAFIFEHIIKRMAP 284


>gi|56243522 syntenin isoform 1 [Homo sapiens]
          Length = 298

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 42/142 (29%), Positives = 69/142 (48%), Gaps = 3/142 (2%)

Query: 593 PAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKR 652
           PA+  G L  GDQ++ ING +  G        ++K    + ++ + I   P   T+ + +
Sbjct: 146 PASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGE-KITMTIRDRPFERTITMHK 203

Query: 653 PDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSV 712
            D    +GF  +NG I S+++   A R G+   H I EINGQ+V+     +I   LS S 
Sbjct: 204 -DSTGHVGFIFKNGKITSIVKDSSAARNGLLTEHNICEINGQNVIGLKDSQIADILSTSG 262

Query: 713 GEIHMKTMPAAMFRLLTGQETP 734
             + +  MPA +F  +  +  P
Sbjct: 263 TVVTITIMPAFIFEHIIKRMAP 284


>gi|134152672 syndecan binding protein 2 isoform a [Homo sapiens]
          Length = 292

 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 35/145 (24%), Positives = 69/145 (47%), Gaps = 3/145 (2%)

Query: 593 PAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKR 652
           PA+  G L  GDQ++ I+G    G        ++K       V   +V   P    +   
Sbjct: 140 PASLVG-LRFGDQLLQIDGRDCAGWSSHKAHQVVKKASGDKIVV--VVRDRPFQRTVTMH 196

Query: 653 PDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSV 712
            D    +GF ++ G I SL++G  A R G+   H + E++GQ+V+    +KI++ L+ + 
Sbjct: 197 KDSMGHVGFVIKKGKIVSLVKGSSAARNGLLTNHYVCEVDGQNVIGLKDKKIMEILATAG 256

Query: 713 GEIHMKTMPAAMFRLLTGQETPLYI 737
             + +  +P+ ++  +  +  P+ +
Sbjct: 257 NVVTLTIIPSVIYEHMVKKLPPVLL 281


>gi|38016916 syndecan binding protein 2 isoform b [Homo sapiens]
          Length = 207

 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 35/145 (24%), Positives = 69/145 (47%), Gaps = 3/145 (2%)

Query: 593 PAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKR 652
           PA+  G L  GDQ++ I+G    G        ++K       V   +V   P    +   
Sbjct: 55  PASLVG-LRFGDQLLQIDGRDCAGWSSHKAHQVVKKASGDKIVV--VVRDRPFQRTVTMH 111

Query: 653 PDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSV 712
            D    +GF ++ G I SL++G  A R G+   H + E++GQ+V+    +KI++ L+ + 
Sbjct: 112 KDSMGHVGFVIKKGKIVSLVKGSSAARNGLLTNHYVCEVDGQNVIGLKDKKIMEILATAG 171

Query: 713 GEIHMKTMPAAMFRLLTGQETPLYI 737
             + +  +P+ ++  +  +  P+ +
Sbjct: 172 NVVTLTIIPSVIYEHMVKKLPPVLL 196


>gi|112382257 InaD-like [Homo sapiens]
          Length = 1801

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 65/283 (22%), Positives = 110/283 (38%), Gaps = 77/283 (27%)

Query: 511  AYQEFLRANGINPEDLSQKEYSDIINTQE------MYNDDLIHFSNSENCK--ELQLEKH 562
            A  + L  NG++  + S +E    +          +Y D+  H+ + EN +   + L+K 
Sbjct: 1481 AGDQILEVNGVDLRNSSHEEAITALRQTPQKVRLVVYRDEA-HYRDEENLEIFPVDLQKK 1539

Query: 563  KGEILGVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATC 622
             G  LG+ +V    GS    V +++++ GG A   G+L  GDQI+S+NG  +      T 
Sbjct: 1540 AGRGLGLSIVGKRNGS---GVFISDIVKGGAADLDGRLIQGDQILSVNGEDMRNASQETV 1596

Query: 623  QGIIKGLKNQTQVKLNIV------------------------SCPP------------VT 646
              I+K  +   Q+++  +                        SC P            V 
Sbjct: 1597 ATILKCAQGLVQLEIGRLRAGSWTSARTTSQNSQGSQQSAHSSCHPSFAPVITGLQNLVG 1656

Query: 647  TVLIKRP------------------DLKYQLGFSVQNG----------IICSLMRGGIAE 678
            T  +  P                  +L   LG S+  G           I  +   G+A 
Sbjct: 1657 TKRVSDPSQKNSGTDMEPRTVEINRELSDALGISIAGGRGSPLGDIPVFIAMIQASGVAA 1716

Query: 679  R-GGVRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMKTM 720
            R   ++VG RI+ INGQ +   +H  +V  L N+ G I ++ +
Sbjct: 1717 RTQKLKVGDRIVSINGQPLDGLSHADVVNLLKNAYGRIILQVV 1759



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 49/182 (26%), Positives = 89/182 (48%), Gaps = 23/182 (12%)

Query: 555  KELQLEKHKGEI-LGVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTS 613
            +E+ +E  KG   LG+ +V  G  + L  +++  +   G AAR G+L  GDQI+ +NG  
Sbjct: 1434 QEMIIEISKGRSGLGLSIV-GGKDTPLNAIVIHEVYEEGAAARDGRLWAGDQILEVNG-- 1490

Query: 614  LVGLPLATCQGIIKGLKNQTQVKLNIV------SCPPVTTVLIKRPDLKYQ----LGFSV 663
             V L  ++ +  I  L+ QT  K+ +V             + I   DL+ +    LG S+
Sbjct: 1491 -VDLRNSSHEEAITALR-QTPQKVRLVVYRDEAHYRDEENLEIFPVDLQKKAGRGLGLSI 1548

Query: 664  ---QNG---IICSLMRGGIAERGGVRV-GHRIIEINGQSVVATAHEKIVQALSNSVGEIH 716
               +NG    I  +++GG A+  G  + G +I+ +NG+ +   + E +   L  + G + 
Sbjct: 1549 VGKRNGSGVFISDIVKGGAADLDGRLIQGDQILSVNGEDMRNASQETVATILKCAQGLVQ 1608

Query: 717  MK 718
            ++
Sbjct: 1609 LE 1610



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 31/110 (28%), Positives = 57/110 (51%), Gaps = 7/110 (6%)

Query: 555  KELQLEKHKGEILGVVVVESGWGSILPT--VILANMMNGGPAARSGKLSIGDQIMSINGT 612
            + +++ +   + LG+ +   G GS L    V +A +   G AAR+ KL +GD+I+SING 
Sbjct: 1675 RTVEINRELSDALGISIA-GGRGSPLGDIPVFIAMIQASGVAARTQKLKVGDRIVSINGQ 1733

Query: 613  SLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKRPDLK--YQLG 660
             L GL  A    ++K      ++ L +V+   ++ +  +  ++   Y LG
Sbjct: 1734 PLDGLSHADVVNLLKNAYG--RIILQVVADTNISAIAAQLENMSTGYHLG 1781



 Score = 37.4 bits (85), Expect = 0.050
 Identities = 39/179 (21%), Positives = 73/179 (40%), Gaps = 45/179 (25%)

Query: 583 VILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKL----- 637
           V++  ++ GG A R G+L  GD I+ I GT++ G+       +++   N  ++ +     
Sbjct: 270 VVVRTIVPGGLADRDGRLQTGDHILKIGGTNVQGMTSEQVAQVLRNCGNSVRMLVARDPA 329

Query: 638 -NIVSCPP--------VTTVLIKRPDLKYQLGFSVQN-----------GI---------- 667
            +I   PP        + TV  K P     L F   N           GI          
Sbjct: 330 GDISVTPPAPAALPVALPTVASKGPGSDSSL-FETYNVELVRKDGQSLGIRIVGYVGTSH 388

Query: 668 --------ICSLMRGGIA-ERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHM 717
                   + S++ G  A   G ++V  +I+ ++G ++   A+  +V+ L N+   +H+
Sbjct: 389 TGEASGIYVKSIIPGSAAYHNGHIQVNDKIVAVDGVNIQGFANHDVVEVLRNAGQVVHL 447



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 15/36 (41%), Positives = 20/36 (55%)

Query: 592  GPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIK 627
            GPAA  G++ IGD+++ IN   L G        IIK
Sbjct: 1273 GPAAADGRMRIGDELLEINNQILYGRSHQNASAIIK 1308



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 24/95 (25%), Positives = 46/95 (48%), Gaps = 1/95 (1%)

Query: 535 INTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANMMNGGPA 594
           +NT+E  + +L  +S      EL ++  KG    ++  +         +++ +++  G A
Sbjct: 667 VNTEEDDDGELALWSPEVKIVEL-VKDCKGLGFSILDYQDPLDPTRSVIVIRSLVADGVA 725

Query: 595 ARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGL 629
            RSG L  GD+++S+N   L    LA    I+K +
Sbjct: 726 ERSGGLLPGDRLVSVNEYCLDNTSLAEAVEILKAV 760


>gi|148746189 multiple PDZ domain protein [Homo sapiens]
          Length = 2041

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 70/262 (26%), Positives = 113/262 (43%), Gaps = 31/262 (11%)

Query: 482  KKQYKMICHVFESEDAQLIAQSIGQAFSV---AYQEFLRANGINPEDLSQKEYSDIINTQ 538
            K   K+  H  E+ D+Q +  + G A      + Q  +     +PE  S +  S   +T 
Sbjct: 1553 KMTVKLTIHA-ENPDSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRS-STP 1610

Query: 539  EMYNDDLIHFSNSENCKELQLEKHKGEI-LGVVVVESGWGSILPTVILANMMNGGPAARS 597
             ++  D         C E  +E  KG   LG+ +V  G  ++L  +I+  +   G A + 
Sbjct: 1611 AIFASDPATCPIIPGC-ETTIEISKGRTGLGLSIV-GGSDTLLGAIIIHEVYEEGAACKD 1668

Query: 598  GKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQ-VKLNIVS----------CPPVT 646
            G+L  GDQI+ +NG   + L  AT    I  L+   Q V+L +            C  +T
Sbjct: 1669 GRLWAGDQILEVNG---IDLRKATHDEAINVLRQTPQRVRLTLYRDEAPYKEEEVCDTLT 1725

Query: 647  TVLIKRPDLKYQLGFSV-----QNGIICS-LMRGGIAERGG-VRVGHRIIEINGQSVVAT 699
              L K+P     LG S+       G+  S +++GGIA+  G +  G +I+ +NG+ V   
Sbjct: 1726 IELQKKPG--KGLGLSIVGKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNA 1783

Query: 700  AHEKIVQALSNSVGEIHMKTMP 721
              E +   L  S G +   T P
Sbjct: 1784 TQEAVAALLKVSEGSLSSFTFP 1805



 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 66/265 (24%), Positives = 110/265 (41%), Gaps = 52/265 (19%)

Query: 511  AYQEFLRANGINPEDLSQKEYSDIINTQE---------MYNDDLIHFSNSENCKEL--QL 559
            A  + L  NGI   DL +  + + IN            +Y D+   +   E C  L  +L
Sbjct: 1673 AGDQILEVNGI---DLRKATHDEAINVLRQTPQRVRLTLYRDEA-PYKEEEVCDTLTIEL 1728

Query: 560  EKHKGEILGVVVVESGWGSILPT-VILANMMNGGPAARSGKLSIGDQIMSINGTSL---- 614
            +K  G+ LG+ +V    G    T V +++++ GG A   G+L  GDQI+ +NG  +    
Sbjct: 1729 QKKPGKGLGLSIV----GKRNDTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNAT 1784

Query: 615  ---VGLPLATCQGII-------------KGLKNQTQVKLNIVSCPPVTTVLIKRPDLKYQ 658
               V   L   +G +             + L++ ++          + TV +K+      
Sbjct: 1785 QEAVAALLKVSEGSLSSFTFPLSGSSTSESLESSSKKNALASEIQGLRTVEMKKGPTD-S 1843

Query: 659  LGFSVQNG---------IICSLMR--GGIAERGGVRVGHRIIEINGQSVVATAHEKIVQA 707
            LG S+  G         I  ++M   G  A+   +RVG RI+ I G S     H + V  
Sbjct: 1844 LGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTSTEGMTHTQAVNL 1903

Query: 708  LSNSVGEIHMKTMPAAMFRLLTGQE 732
            L N+ G I M+ +      ++TG +
Sbjct: 1904 LKNASGSIEMQVVAGGDVSVVTGHQ 1928



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 37/118 (31%), Positives = 61/118 (51%), Gaps = 10/118 (8%)

Query: 522  NPEDLSQKEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILP 581
            N E+L  KE    + T    +D  +  S+ +N + L+L K +G  LG+ + E      L 
Sbjct: 1453 NSENLQNKETEPTVTT----SDAAVDLSSFKNVQHLELPKDQGG-LGIAISEE---DTLS 1504

Query: 582  TVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNI 639
             VI+ ++   G AA  G+L +GDQI++++   +VG P+     ++K  K    VKL I
Sbjct: 1505 GVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPIEKFISLLKTAK--MTVKLTI 1560



 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 50/216 (23%), Positives = 92/216 (42%), Gaps = 45/216 (20%)

Query: 549  SNSENCKELQLEKHKGEILGVVVVESGWGSILPTV--ILANMMNGGPAARSGKLSIGDQI 606
            S  +  + ++++K   + LG+ +   G GS L  V   +A M   G AA++ KL +GD+I
Sbjct: 1826 SEIQGLRTVEMKKGPTDSLGISIA-GGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRI 1884

Query: 607  MSINGTSLVGLPLATCQGIIKGLKNQTQVKL------------------NIVSCPPVTTV 648
            ++I GTS  G+       ++K      ++++                  + +S   +T+ 
Sbjct: 1885 VTICGTSTEGMTHTQAVNLLKNASGSIEMQVVAGGDVSVVTGHQQEPASSSLSFTGLTSS 1944

Query: 649  LIKRPDL-------------KYQLGFSVQNG-----------IICSLMRGGIAERGGVRV 684
             I + DL                LGFS+  G           +     +G  +E G ++ 
Sbjct: 1945 SIFQDDLGPPQCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKR 2004

Query: 685  GHRIIEINGQSVVATAHEKIVQALSNSVGEIHMKTM 720
            G +II +NGQS+    HE+ V  L  + G + +  +
Sbjct: 2005 GDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLMVL 2040



 Score = 39.3 bits (90), Expect = 0.013
 Identities = 31/99 (31%), Positives = 50/99 (50%), Gaps = 10/99 (10%)

Query: 535  INTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSI---LPTVILANMMNG 591
            + +  ++ DDL        CK + LE+   + LG  +V  G+GS    LP + +  +   
Sbjct: 1941 LTSSSIFQDDL----GPPQCKSITLERGP-DGLGFSIV-GGYGSPHGDLP-IYVKTVFAK 1993

Query: 592  GPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLK 630
            G A+  G+L  GDQI+++NG SL G+       I+K  K
Sbjct: 1994 GAASEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTK 2032



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 26/90 (28%), Positives = 45/90 (50%), Gaps = 12/90 (13%)

Query: 574 SGWGSILPTVI----LANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGL 629
           SG G  L   +    + +++  GP   SGKL  GD+++ +NG +L+G      Q ++  L
Sbjct: 563 SGLGISLEATVGHHFIRSVLPEGPVGHSGKLFSGDELLEVNGITLLG---ENHQDVVNIL 619

Query: 630 KNQTQVKLNIVSC----PPVTTVLIKRPDL 655
           K +  +++ +V C    PP T   +   DL
Sbjct: 620 K-ELPIEVTMVCCRRTVPPTTQSELDSLDL 648



 Score = 34.7 bits (78), Expect = 0.33
 Identities = 14/45 (31%), Positives = 31/45 (68%)

Query: 583  VILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIK 627
            +I+ ++++GG  +R G+++IGD I+SIN  S + +  A  + +++
Sbjct: 1031 MIVRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLR 1075



 Score = 33.1 bits (74), Expect = 0.95
 Identities = 18/74 (24%), Positives = 39/74 (52%), Gaps = 7/74 (9%)

Query: 548  FSNSENCKELQLEKHKGEILGVVVVES-GWGS------ILPTVILANMMNGGPAARSGKL 600
            +SN    + ++L +   + LG+ +V   G GS      ++  + + +++   PA ++G L
Sbjct: 1143 YSNWNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNGTL 1202

Query: 601  SIGDQIMSINGTSL 614
              GD+I+ ++G  L
Sbjct: 1203 KPGDRIVEVDGMDL 1216



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 41/188 (21%), Positives = 74/188 (39%), Gaps = 48/188 (25%)

Query: 583 VILANMMNGGPAARSGKLSIGDQIMSINGTSLVGL----------------PLATCQGII 626
           VI+  ++ GG A + G+L  GD I+ I  T L G+                 L   +G I
Sbjct: 279 VIVKTILPGGVADQHGRLCSGDHILKIGDTDLAGMSSEQVAQVLRQCGNRVKLMIARGAI 338

Query: 627 KGLKNQTQVKLNIVSCPPVTTVLIKRPDLKYQLG-----FSVQ----------------- 664
           +     T + + + S P  T  L  R D   Q G     F V+                 
Sbjct: 339 EERTAPTALGITLSSSPTSTPEL--RVDASTQKGEESETFDVELTKNVQGLGITIAGYIG 396

Query: 665 ------NGI-ICSLMRGGIAERGG-VRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIH 716
                 +GI + S+ +    E  G +++G +II ++G ++    +++ V+ L ++   + 
Sbjct: 397 DKKLEPSGIFVKSITKSSAVEHDGRIQIGDQIIAVDGTNLQGFTNQQAVEVLRHTGQTVL 456

Query: 717 MKTMPAAM 724
           +  M   M
Sbjct: 457 LTLMRRGM 464



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 22/93 (23%), Positives = 46/93 (49%), Gaps = 2/93 (2%)

Query: 555 KELQLEK-HKGEILGVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTS 613
           + ++LEK  KG    ++  +         +I+ +++ GG A + G+L  GD++M +N  +
Sbjct: 699 QHIELEKGSKGLGFSILDYQDPIDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVN 758

Query: 614 LVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVT 646
           L    L      +KG  + T V++ +    P++
Sbjct: 759 LENSSLEEAVEALKGAPSGT-VRIGVAKPLPLS 790



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 15/54 (27%), Positives = 27/54 (50%)

Query: 582  TVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQV 635
            +V +  +   G A + G+L I D+++ ING  L G        IIK   ++ ++
Sbjct: 1374 SVFIVGIDPNGAAGKDGRLQIADELLEINGQILYGRSHQNASSIIKCAPSKVKI 1427


>gi|4557529 post-synaptic density protein 95 isoform 1 [Homo
           sapiens]
          Length = 767

 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 42/157 (26%), Positives = 76/157 (48%), Gaps = 25/157 (15%)

Query: 581 PTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQ-TQVKLNI 639
           P++ +  ++ GG AA+ G+L + D I+ +N    V +   T    ++ LK   + V+L +
Sbjct: 135 PSIFITKIIPGGAAAQDGRLRVNDSILFVNE---VDVREVTHSAAVEALKEAGSIVRLYV 191

Query: 640 V-SCPPVTTV----LIKRPDLKYQLGFSVQNGI------------ICSLMRGGIAERGG- 681
           +   PP   V    LIK P     LGFS+  G+            +  ++ GG A + G 
Sbjct: 192 MRRKPPAEKVMEIKLIKGPK---GLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGR 248

Query: 682 VRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMK 718
           +++G +I+ +N   +    HE  V AL N+   +++K
Sbjct: 249 LQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLK 285



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 23/56 (41%), Positives = 33/56 (58%), Gaps = 8/56 (14%)

Query: 562 HKGEI-LGVVVV--ESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSL 614
           H+G   LG  +V  E G G     + ++ ++ GGPA  SG+L  GDQI+S+NG  L
Sbjct: 360 HRGSTGLGFNIVGGEDGEG-----IFISFILAGGPADLSGELRKGDQILSVNGVDL 410



 Score = 31.2 bits (69), Expect = 3.6
 Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 7/60 (11%)

Query: 659 LGFSVQNG------IICSLMRGGIAERGG-VRVGHRIIEINGQSVVATAHEKIVQALSNS 711
           LGF++  G       I  ++ GG A+  G +R G +I+ +NG  +   +HE+   AL N+
Sbjct: 366 LGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNA 425


>gi|192447426 post-synaptic density protein 95 isoform 2 [Homo
           sapiens]
          Length = 721

 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 42/157 (26%), Positives = 76/157 (48%), Gaps = 25/157 (15%)

Query: 581 PTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQ-TQVKLNI 639
           P++ +  ++ GG AA+ G+L + D I+ +N    V +   T    ++ LK   + V+L +
Sbjct: 89  PSIFITKIIPGGAAAQDGRLRVNDSILFVNE---VDVREVTHSAAVEALKEAGSIVRLYV 145

Query: 640 V-SCPPVTTV----LIKRPDLKYQLGFSVQNGI------------ICSLMRGGIAERGG- 681
           +   PP   V    LIK P     LGFS+  G+            +  ++ GG A + G 
Sbjct: 146 MRRKPPAEKVMEIKLIKGPK---GLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGR 202

Query: 682 VRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMK 718
           +++G +I+ +N   +    HE  V AL N+   +++K
Sbjct: 203 LQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLK 239



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 23/56 (41%), Positives = 33/56 (58%), Gaps = 8/56 (14%)

Query: 562 HKGEI-LGVVVV--ESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSL 614
           H+G   LG  +V  E G G     + ++ ++ GGPA  SG+L  GDQI+S+NG  L
Sbjct: 314 HRGSTGLGFNIVGGEDGEG-----IFISFILAGGPADLSGELRKGDQILSVNGVDL 364



 Score = 31.2 bits (69), Expect = 3.6
 Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 7/60 (11%)

Query: 659 LGFSVQNG------IICSLMRGGIAERGG-VRVGHRIIEINGQSVVATAHEKIVQALSNS 711
           LGF++  G       I  ++ GG A+  G +R G +I+ +NG  +   +HE+   AL N+
Sbjct: 320 LGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNA 379


>gi|223890252 glutamate receptor interacting protein 1 [Homo
           sapiens]
          Length = 1076

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 38/163 (23%), Positives = 73/163 (44%), Gaps = 20/163 (12%)

Query: 583 VILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLN---- 638
           V++  +  GGPA R G +  GD+++S++G  L+G   A    I+K    +  + +     
Sbjct: 180 VVITCVRPGGPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSILKQCGQEAALLIEYDVS 239

Query: 639 -----IVSCPPVTTVLIKRPDLKYQLGFSVQNGIICS--------LMRGGIAER-GGVRV 684
                  +  P+   + K P     LG ++   + C+        +    IA+R G + V
Sbjct: 240 VMDSVATASGPLLVEVAKTPGA--SLGVALTTSMCCNKQVIVIDKIKSASIADRCGALHV 297

Query: 685 GHRIIEINGQSVVATAHEKIVQALSNSVGEIHMKTMPAAMFRL 727
           G  I+ I+G S+      +  Q L+N+  ++ ++ +P    RL
Sbjct: 298 GDHILSIDGTSMEYCTLAEATQFLANTTDQVKLEILPHHQTRL 340



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 42/173 (24%), Positives = 81/173 (46%), Gaps = 24/173 (13%)

Query: 557 LQLEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVG 616
           ++L K +G  LG+ V         P V  +N+  GG AARS +L +GD I ++NG +L  
Sbjct: 54  VELMKKEGTTLGLTVSGGIDKDGKPRV--SNLRQGGIAARSDQLDVGDYIKAVNGINLAK 111

Query: 617 LPLATCQGIIKGLKNQTQVKLNIVSCPPV----TTVLIKRPDLKYQ-----LGFSVQNG- 666
                   ++K +  +  +++     PPV    ++V+ +  ++         GF ++ G 
Sbjct: 112 FRHDEIISLLKNVGERVVLEVE-YELPPVSVQGSSVIFRTVEVTLHKEGNTFGFVIRGGA 170

Query: 667 ----------IICSLMRGGIAER-GGVRVGHRIIEINGQSVVATAHEKIVQAL 708
                     +I  +  GG A+R G ++ G R++ ++G  ++ T H + +  L
Sbjct: 171 HDDRNKSRPVVITCVRPGGPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSIL 223



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 49/203 (24%), Positives = 89/203 (43%), Gaps = 27/203 (13%)

Query: 519 NGINPEDLSQKEYSDIIN--------TQEMYNDDLIHFSNSENCKELQLEKHKGEILGVV 570
           NGI  ED + +E S ++         T E+  D       S     ++L K     LG+ 
Sbjct: 476 NGIPTEDSTFEEASQLLRDSSITSKVTLEIEFDVAESVIPSSGTFHVKLPKKHNVELGIT 535

Query: 571 VVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLK 630
           +           ++++++  G  A R+G L +GD++++I+   L    +     I++  +
Sbjct: 536 ISSPSSRKPGDPLVISDIKKGSVAHRTGTLELGDKLLAIDNIRLDNCSMEDAVQILQQCE 595

Query: 631 NQTQVKL---------NIVSCPPVTTVLIKRPDLKYQLGFSVQNG-------IICSLMRG 674
           +  ++K+            S   + TV +KR      LG ++          II SL +G
Sbjct: 596 DLVKLKIRKDEDNSDEQESSGAIIYTVELKR--YGGPLGITISGTEEPFDPIIISSLTKG 653

Query: 675 GIAER-GGVRVGHRIIEINGQSV 696
           G+AER G + +G RI+ IN  S+
Sbjct: 654 GLAERTGAIHIGDRILAINSSSL 676



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 31/108 (28%), Positives = 56/108 (51%), Gaps = 5/108 (4%)

Query: 516 LRANGINPEDLSQ--KEYSDIINTQEMYNDDLIHFSNSENCKELQLE-KHKGEILGVVVV 572
           +R +  + ED  Q  ++  D++  +   ++D      S       +E K  G  LG+ + 
Sbjct: 577 IRLDNCSMEDAVQILQQCEDLVKLKIRKDEDNSDEQESSGAIIYTVELKRYGGPLGITI- 635

Query: 573 ESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLA 620
            SG       +I++++  GG A R+G + IGD+I++IN +SL G PL+
Sbjct: 636 -SGTEEPFDPIIISSLTKGGLAERTGAIHIGDRILAINSSSLKGKPLS 682



 Score = 35.0 bits (79), Expect = 0.25
 Identities = 33/143 (23%), Positives = 60/143 (41%), Gaps = 17/143 (11%)

Query: 593 PAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNI------VSCPPVT 646
           PA R G L IGD++M+ING             +++     ++V L I         P   
Sbjct: 459 PAERCGVLQIGDRVMAINGIPTEDSTFEEASQLLRDSSITSKVTLEIEFDVAESVIPSSG 518

Query: 647 TVLIKRPDL-KYQLGFSVQNG---------IICSLMRGGIAER-GGVRVGHRIIEINGQS 695
           T  +K P     +LG ++ +          +I  + +G +A R G + +G +++ I+   
Sbjct: 519 TFHVKLPKKHNVELGITISSPSSRKPGDPLVISDIKKGSVAHRTGTLELGDKLLAIDNIR 578

Query: 696 VVATAHEKIVQALSNSVGEIHMK 718
           +   + E  VQ L      + +K
Sbjct: 579 LDNCSMEDAVQILQQCEDLVKLK 601



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 23/64 (35%), Positives = 34/64 (53%), Gaps = 9/64 (14%)

Query: 659 LGFSVQNGI-------ICSLMRGGIAERGG-VRVGHRIIEINGQSVVATAHEKIVQALSN 710
           LG +V  GI       + +L +GGIA R   + VG  I  +NG ++    H++I+  L N
Sbjct: 64  LGLTVSGGIDKDGKPRVSNLRQGGIAARSDQLDVGDYIKAVNGINLAKFRHDEIISLLKN 123

Query: 711 SVGE 714
            VGE
Sbjct: 124 -VGE 126


>gi|119943106 synapse-associated protein 102 isoform a [Homo
           sapiens]
          Length = 817

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 33/151 (21%), Positives = 70/151 (46%), Gaps = 13/151 (8%)

Query: 581 PTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIV 640
           P + +  ++ GG AA  G+L + D ++ +N   +  +  +     +K      ++ +   
Sbjct: 158 PGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVSEVVHSRAVEALKEAGPVVRLVVRRR 217

Query: 641 SCPPVTTVLIKRPDLKYQLGFSVQNGI------------ICSLMRGGIAERGG-VRVGHR 687
             PP T + +        LGFS+  GI            I  ++ GG A++ G +++G R
Sbjct: 218 QPPPETIMEVNLLKGPKGLGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDR 277

Query: 688 IIEINGQSVVATAHEKIVQALSNSVGEIHMK 718
           ++ +N  ++    HE+ V +L N+   +++K
Sbjct: 278 LLAVNNTNLQDVRHEEAVASLKNTSDMVYLK 308



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 23/56 (41%), Positives = 34/56 (60%), Gaps = 8/56 (14%)

Query: 562 HKGEI-LGVVVV--ESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSL 614
           HKG   LG  +V  E G G     + ++ ++ GGPA  SG+L  GD+I+S+NG +L
Sbjct: 390 HKGSTGLGFNIVGGEDGEG-----IFVSFILAGGPADLSGELRRGDRILSVNGVNL 440



 Score = 30.4 bits (67), Expect = 6.2
 Identities = 18/60 (30%), Positives = 31/60 (51%), Gaps = 7/60 (11%)

Query: 659 LGFSVQNG------IICSLMRGGIAERGG-VRVGHRIIEINGQSVVATAHEKIVQALSNS 711
           LGF++  G       +  ++ GG A+  G +R G RI+ +NG ++    HE+   AL  +
Sbjct: 396 LGFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAALKRA 455


>gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]
          Length = 904

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 38/161 (23%), Positives = 80/161 (49%), Gaps = 20/161 (12%)

Query: 582 TVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQ-TQVKLNIV 640
           ++ +  ++ GG AA+ G+L + D I+ +N    V +   T    ++ LK   + V+L + 
Sbjct: 252 SIFITKIITGGAAAQDGRLRVNDCILRVNE---VDVRDVTHSKAVEALKEAGSIVRLYVK 308

Query: 641 SCPPVTTVLIKRPDLK--YQLGFSVQNGI------------ICSLMRGGIAERGG-VRVG 685
              PV+  +++   +K    LGFS+  G+            +  ++ GG A + G +++G
Sbjct: 309 RRKPVSEKIMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIG 368

Query: 686 HRIIEINGQSVVATAHEKIVQALSNSVGEIHMK-TMPAAMF 725
            +++ +N   +    HE+ V AL N+   +++K   P +M+
Sbjct: 369 DKLLAVNNVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMY 409



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 44/192 (22%), Positives = 72/192 (37%), Gaps = 65/192 (33%)

Query: 582 TVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQ--------- 632
           ++ +  ++ GG A + GKL IGD+++++N    V L   T +  +  LKN          
Sbjct: 347 SIYVTKIIEGGAAHKDGKLQIGDKLLAVNN---VCLEEVTHEEAVTALKNTSDFVYLKVA 403

Query: 633 --TQVKLNIVSCPPVTTVLIKRP-----------------DLKYQ--------------- 658
             T + +N    PP  T    +P                   +Y                
Sbjct: 404 KPTSMYMNDGYAPPDITNSSSQPVDNHVSPSSFLGQTPASPARYSPVSKAVLGDDEITRE 463

Query: 659 ------------LGFSVQNG------IICSLMRGGIAERGG-VRVGHRIIEINGQSVVAT 699
                       LGF++  G       I  ++ GG A+  G +R G RII +N   + A 
Sbjct: 464 PRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAA 523

Query: 700 AHEKIVQALSNS 711
           +HE+   AL N+
Sbjct: 524 SHEQAAAALKNA 535



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 27/76 (35%), Positives = 40/76 (52%), Gaps = 11/76 (14%)

Query: 562 HKGEI-LGVVVV--ESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLP 618
           H+G   LG  +V  E G G     + ++ ++ GGPA  SG+L  GD+I+S+N    V L 
Sbjct: 470 HRGSTGLGFNIVGGEDGEG-----IFISFILAGGPADLSGELRKGDRIISVNS---VDLR 521

Query: 619 LATCQGIIKGLKNQTQ 634
            A+ +     LKN  Q
Sbjct: 522 AASHEQAAAALKNAGQ 537


>gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]
          Length = 926

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 38/161 (23%), Positives = 80/161 (49%), Gaps = 20/161 (12%)

Query: 582 TVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQ-TQVKLNIV 640
           ++ +  ++ GG AA+ G+L + D I+ +N    V +   T    ++ LK   + V+L + 
Sbjct: 252 SIFITKIITGGAAAQDGRLRVNDCILRVNE---VDVRDVTHSKAVEALKEAGSIVRLYVK 308

Query: 641 SCPPVTTVLIKRPDLK--YQLGFSVQNGI------------ICSLMRGGIAERGG-VRVG 685
              PV+  +++   +K    LGFS+  G+            +  ++ GG A + G +++G
Sbjct: 309 RRKPVSEKIMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIG 368

Query: 686 HRIIEINGQSVVATAHEKIVQALSNSVGEIHMK-TMPAAMF 725
            +++ +N   +    HE+ V AL N+   +++K   P +M+
Sbjct: 369 DKLLAVNNVCLEEVTHEEAVTALKNTSDFVYLKVAKPTSMY 409



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 44/192 (22%), Positives = 72/192 (37%), Gaps = 65/192 (33%)

Query: 582 TVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQ--------- 632
           ++ +  ++ GG A + GKL IGD+++++N    V L   T +  +  LKN          
Sbjct: 347 SIYVTKIIEGGAAHKDGKLQIGDKLLAVNN---VCLEEVTHEEAVTALKNTSDFVYLKVA 403

Query: 633 --TQVKLNIVSCPPVTTVLIKRP-----------------DLKYQ--------------- 658
             T + +N    PP  T    +P                   +Y                
Sbjct: 404 KPTSMYMNDGYAPPDITNSSSQPVDNHVSPSSFLGQTPASPARYSPVSKAVLGDDEITRE 463

Query: 659 ------------LGFSVQNG------IICSLMRGGIAERGG-VRVGHRIIEINGQSVVAT 699
                       LGF++  G       I  ++ GG A+  G +R G RII +N   + A 
Sbjct: 464 PRKVVLHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIISVNSVDLRAA 523

Query: 700 AHEKIVQALSNS 711
           +HE+   AL N+
Sbjct: 524 SHEQAAAALKNA 535



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 27/76 (35%), Positives = 40/76 (52%), Gaps = 11/76 (14%)

Query: 562 HKGEI-LGVVVV--ESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLP 618
           H+G   LG  +V  E G G     + ++ ++ GGPA  SG+L  GD+I+S+N    V L 
Sbjct: 470 HRGSTGLGFNIVGGEDGEG-----IFISFILAGGPADLSGELRKGDRIISVNS---VDLR 521

Query: 619 LATCQGIIKGLKNQTQ 634
            A+ +     LKN  Q
Sbjct: 522 AASHEQAAAALKNAGQ 537


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 67/286 (23%), Positives = 101/286 (35%), Gaps = 41/286 (14%)

Query: 28   EPESEDMELPLEGYVPEGLELAALRPESPAPEEQECHNHSPDGDSSSDYVNNTSEEEDYD 87
            +PESED+E P   +         ++PES   E  E    +     S + +    E+E   
Sbjct: 1884 QPESEDVETPEAEW--------EVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPES 1935

Query: 88   EG--------LPEEEEGITYYIRYCPEDDSYLEGMDCNGEEYLAHSAHPVDTDECQ-EAV 138
            EG          +E EG T       E     E      E+  A     V+T E + EA 
Sbjct: 1936 EGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVE-VETQEAEGEAQ 1994

Query: 139  EEWTDSAGPHPHG------HEAEGSQDYPDGQLPIPEDEPSVLEAHDQEEDGHYCASKEG 192
             E  D   P   G       EA+   D  + Q     +E   +E   Q+ +G      +G
Sbjct: 1995 PESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDG 2054

Query: 193  YQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMTSITSASEASPEH 252
             +     EA      +   ++  +G+   + ED+D   AE              EA PE 
Sbjct: 2055 VE---APEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAE-------------GEAQPES 2098

Query: 253  GPEPGPEDSVEACPPIKASCSPSRHEARPKSLNL-LPEAKHPGDPQ 297
                 PE   EA          +  EA+P+S  +  PEA+    P+
Sbjct: 2099 EGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPE 2144



 Score = 34.7 bits (78), Expect = 0.33
 Identities = 65/322 (20%), Positives = 118/322 (36%), Gaps = 64/322 (19%)

Query: 10   GSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEEQECHNHSPD 69
            GSG  D+          Q+P   D    +E    EG      +PES   E  E      +
Sbjct: 1807 GSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEG----EAQPESEGVEAPEA-----E 1857

Query: 70   GDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEEYLAHSAHPV 129
            GD+          +E   E  PE E+               +E  +  GE      +  V
Sbjct: 1858 GDA----------QEAEGEAQPESED---------------VEAPEAEGEAQ--PESEDV 1890

Query: 130  DTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQEEDGHYCAS 189
            +T E +  V+  ++ A       EA+   +  +      EDEP    A  QE +    A+
Sbjct: 1891 ETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEE---AA 1947

Query: 190  KEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMTSITSASEAS 249
            +E      PE       +     +  + + + + ED++ +  E++            EA 
Sbjct: 1948 QEAEGQTQPE-------SEVIESQEAEEEAQPESEDVEALEVEVE----------TQEAE 1990

Query: 250  PEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGFKPKTRTPEE 309
             E  PE    + VEA P  +     +  EA+P+S  +  + K  G+  +  + +T    +
Sbjct: 1991 GEAQPE---SEDVEA-PEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGET----Q 2042

Query: 310  RLKWPHEQVCNGLEQPRKQQRS 331
            + +   +   +G+E P  ++ +
Sbjct: 2043 KTEGDAQPESDGVEAPEAEEEA 2064


>gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]
          Length = 749

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 40/154 (25%), Positives = 73/154 (47%), Gaps = 19/154 (12%)

Query: 581 PTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQ-VKLNI 639
           P + +  ++ GG AA  G+L + D I+ +N    V +   +    ++ LK     V+L +
Sbjct: 74  PGIFITKIIPGGAAAEDGRLRVNDCILRVNE---VDVSEVSHSKAVEALKEAGSIVRLYV 130

Query: 640 VSCPPV--TTVLIKRPDLKYQLGFSVQNGI------------ICSLMRGGIAERGG-VRV 684
               P+  T V IK       LGFS+  G+            +  ++ GG A++ G ++V
Sbjct: 131 RRRRPILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQV 190

Query: 685 GHRIIEINGQSVVATAHEKIVQALSNSVGEIHMK 718
           G R++ +N  S+    HE+ V  L N+   +++K
Sbjct: 191 GDRLLMVNNYSLEEVTHEEAVAILKNTSEVVYLK 224



 Score = 39.3 bits (90), Expect = 0.013
 Identities = 27/70 (38%), Positives = 37/70 (52%), Gaps = 8/70 (11%)

Query: 562 HKGEI-LGVVVV--ESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLP 618
           HKG   LG  +V  E G G     + ++ ++ GGPA  SG+L  GDQI+S+NG  L G  
Sbjct: 322 HKGSTGLGFNIVGGEDGEG-----IFVSFILAGGPADLSGELQRGDQILSVNGIDLRGAS 376

Query: 619 LATCQGIIKG 628
                  +KG
Sbjct: 377 HEQAAAALKG 386



 Score = 33.5 bits (75), Expect = 0.73
 Identities = 20/72 (27%), Positives = 40/72 (55%), Gaps = 5/72 (6%)

Query: 582 TVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVS 641
           ++ +  +++GG A + G+L +GD+++ +N  SL  +   T +  +  LKN ++V    V 
Sbjct: 170 SIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEV---THEEAVAILKNTSEVVYLKVG 226

Query: 642 CPPVTTVLIKRP 653
            P  TT+ +  P
Sbjct: 227 KP--TTIYMTDP 236


>gi|218156338 chapsyn-110 isoform 1 [Homo sapiens]
          Length = 975

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 40/154 (25%), Positives = 73/154 (47%), Gaps = 19/154 (12%)

Query: 581 PTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQ-VKLNI 639
           P + +  ++ GG AA  G+L + D I+ +N    V +   +    ++ LK     V+L +
Sbjct: 230 PGIFITKIIPGGAAAEDGRLRVNDCILRVNE---VDVSEVSHSKAVEALKEAGSIVRLYV 286

Query: 640 VSCPPV--TTVLIKRPDLKYQLGFSVQNGI------------ICSLMRGGIAERGG-VRV 684
               P+  T V IK       LGFS+  G+            +  ++ GG A++ G ++V
Sbjct: 287 RRRRPILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQV 346

Query: 685 GHRIIEINGQSVVATAHEKIVQALSNSVGEIHMK 718
           G R++ +N  S+    HE+ V  L N+   +++K
Sbjct: 347 GDRLLMVNNYSLEEVTHEEAVAILKNTSEVVYLK 380



 Score = 39.3 bits (90), Expect = 0.013
 Identities = 27/70 (38%), Positives = 37/70 (52%), Gaps = 8/70 (11%)

Query: 562 HKGEI-LGVVVV--ESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLP 618
           HKG   LG  +V  E G G     + ++ ++ GGPA  SG+L  GDQI+S+NG  L G  
Sbjct: 530 HKGSTGLGFNIVGGEDGEG-----IFVSFILAGGPADLSGELQRGDQILSVNGIDLRGAS 584

Query: 619 LATCQGIIKG 628
                  +KG
Sbjct: 585 HEQAAAALKG 594



 Score = 33.5 bits (75), Expect = 0.73
 Identities = 20/72 (27%), Positives = 40/72 (55%), Gaps = 5/72 (6%)

Query: 582 TVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVS 641
           ++ +  +++GG A + G+L +GD+++ +N  SL  +   T +  +  LKN ++V    V 
Sbjct: 326 SIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEV---THEEAVAILKNTSEVVYLKVG 382

Query: 642 CPPVTTVLIKRP 653
            P  TT+ +  P
Sbjct: 383 KP--TTIYMTDP 392


>gi|91199538 chapsyn-110 isoform 2 [Homo sapiens]
          Length = 870

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 40/154 (25%), Positives = 73/154 (47%), Gaps = 19/154 (12%)

Query: 581 PTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQ-VKLNI 639
           P + +  ++ GG AA  G+L + D I+ +N    V +   +    ++ LK     V+L +
Sbjct: 125 PGIFITKIIPGGAAAEDGRLRVNDCILRVNE---VDVSEVSHSKAVEALKEAGSIVRLYV 181

Query: 640 VSCPPV--TTVLIKRPDLKYQLGFSVQNGI------------ICSLMRGGIAERGG-VRV 684
               P+  T V IK       LGFS+  G+            +  ++ GG A++ G ++V
Sbjct: 182 RRRRPILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQV 241

Query: 685 GHRIIEINGQSVVATAHEKIVQALSNSVGEIHMK 718
           G R++ +N  S+    HE+ V  L N+   +++K
Sbjct: 242 GDRLLMVNNYSLEEVTHEEAVAILKNTSEVVYLK 275



 Score = 39.3 bits (90), Expect = 0.013
 Identities = 27/70 (38%), Positives = 37/70 (52%), Gaps = 8/70 (11%)

Query: 562 HKGEI-LGVVVV--ESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLP 618
           HKG   LG  +V  E G G     + ++ ++ GGPA  SG+L  GDQI+S+NG  L G  
Sbjct: 425 HKGSTGLGFNIVGGEDGEG-----IFVSFILAGGPADLSGELQRGDQILSVNGIDLRGAS 479

Query: 619 LATCQGIIKG 628
                  +KG
Sbjct: 480 HEQAAAALKG 489



 Score = 33.5 bits (75), Expect = 0.73
 Identities = 20/72 (27%), Positives = 40/72 (55%), Gaps = 5/72 (6%)

Query: 582 TVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVS 641
           ++ +  +++GG A + G+L +GD+++ +N  SL  +   T +  +  LKN ++V    V 
Sbjct: 221 SIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEV---THEEAVAILKNTSEVVYLKVG 277

Query: 642 CPPVTTVLIKRP 653
            P  TT+ +  P
Sbjct: 278 KP--TTIYMTDP 287


>gi|38570142 membrane protein, palmitoylated 5 [Homo sapiens]
          Length = 675

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 73/332 (21%), Positives = 130/332 (39%), Gaps = 68/332 (20%)

Query: 293 PGDPQRGFKPKTRTPE-ERLKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASF 351
           PGD      P  R+ + ER++   E +    E+  K+Q  DLN  +        KK+A  
Sbjct: 40  PGDLGTRMMPIRRSAQLERIRQQQEDMRRRREEEGKKQELDLNSSM------RLKKLAQI 93

Query: 352 PSFVAVPGPCEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKNSEG-- 409
           P    +  P    D  +GI+               +P   +++++ ++  S +K+ +   
Sbjct: 94  PPKTGIDNPMF--DTEEGIVL-------------ESPHYAVKILEIEDLFSSLKHIQHTL 138

Query: 410 -DAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPR--- 465
            D+Q+  ++ L +      V N D Q     H            N + +   +  P    
Sbjct: 139 VDSQSQEDISLLLQL----VQNKDFQNAFKIH------------NAITVHMNKASPPFPL 182

Query: 466 -SASQDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPE 524
            S +QD       AQE +   K + H    E   L+     QA  +A+ +          
Sbjct: 183 ISNAQDL------AQEVQTVLKPVHHKEGQELTALLNTPHIQALLLAHDKVAE------- 229

Query: 525 DLSQKEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVI 584
              Q+   + I  + +Y    I     E  K +++EK +   LG  V        + +VI
Sbjct: 230 ---QEMQLEPITDERVYES--IGQYGGETVKIVRIEKARDIPLGATVRNE-----MDSVI 279

Query: 585 LANMMNGGPAARSGKLSIGDQIMSINGTSLVG 616
           ++ ++ GG A +SG L  GD+++ ING  + G
Sbjct: 280 ISRIVKGGAAEKSGLLHEGDEVLEINGIEIRG 311


>gi|169212742 PREDICTED: similar to hCG1654128 [Homo sapiens]
          Length = 1015

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 61/219 (27%), Positives = 86/219 (39%), Gaps = 39/219 (17%)

Query: 53  PESPAPEEQECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLE 112
           PE  +P E +        + +S   +   ++ED  E     E G+       PED    E
Sbjct: 236 PEDASPTEHDVGQEEDGPEDASPTEHGVDQQEDGPEDASPTEHGVDQQ-EDGPEDARPTE 294

Query: 113 -GMDC--NGEEYLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPE 169
            G+D   +G E  + + H VD  E      +  + A P  HG + E      DG    PE
Sbjct: 295 HGVDQEEDGPEDASLTEHGVDQQE------DGPEDASPTEHGIDQE-----EDG----PE 339

Query: 170 DEPSVLEAHDQEEDGHYCASKEGYQDYYPEEANGNTGASP--YRLRRGDG--DLEDQEED 225
           D        DQEEDG   AS   ++    +E +G   ASP  + + + DG  D    E  
Sbjct: 340 DASPTEHGVDQEEDGPEDASPTEHEHGVDQEEDGPEDASPTEHGVDQEDGPEDARPTEHG 399

Query: 226 IDQIVAEIKMSLSMTSITSASEASP-EHG--PEPGPEDS 261
           +DQ                  +A P EHG   E GPED+
Sbjct: 400 VDQ-------------EDGPEDARPTEHGVDQEDGPEDA 425


>gi|222446609 rai-like protein [Homo sapiens]
          Length = 630

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 55/270 (20%), Positives = 108/270 (40%), Gaps = 64/270 (23%)

Query: 307 PEERLKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGPCEP--- 363
           P  +L+   +   +G   P          P    ++   +  A  P    +PGP EP   
Sbjct: 115 PRLKLQESRDPGSSGPSSPETSLSRSGTAPPPQQDLVGHRATALTPDSCPLPGPGEPTLR 174

Query: 364 --------EDLID-GIIFAANYLGSTQLL-SERNPSKNIRMMQAQEAVSR---------- 403
                   + L+  G+ +   Y+G  ++L S R+    +R    +EA+SR          
Sbjct: 175 SRQDRHFLQHLLGMGMNYCVRYMGCVEVLQSMRSLDFGMRTQVTREAISRLCEAVPGANG 234

Query: 404 -VKNSEGDAQTLTEV-------------DLFISTQRIKVLNADTQETMMDHALRTISYIA 449
            +K  +   + L+ V              L IST  + ++N D Q+ + +H +++IS+ +
Sbjct: 235 AIKKRKPPVKFLSTVLGKSNLQFSGMNIKLTISTCSLTLMNLDNQQIIANHHMQSISFAS 294

Query: 450 ----DIGNIVVLMARRRMPRSASQDCIETTPGAQEGKKQYKMICHVFESED--AQLIAQS 503
               D  + V  +A+  + + A                     CH+ E  +  AQ +  +
Sbjct: 295 GGDPDTTDYVAYVAKDPVNQRA---------------------CHILECHNGMAQDVIST 333

Query: 504 IGQAFSVAYQEFLRANGINPEDLSQKEYSD 533
           IGQAF + ++++L+   +N    S++ + D
Sbjct: 334 IGQAFELRFKQYLKNPSLNTSCESEEVHID 363


>gi|10835173 nitric oxide synthase 1, neuronal [Homo sapiens]
          Length = 1434

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 28/85 (32%), Positives = 48/85 (56%), Gaps = 3/85 (3%)

Query: 553 NCKELQLEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGT 612
           N   ++L K K   LG +V E       P VI+++++ GG A +SG +  GD I+++NG 
Sbjct: 14  NVISVRLFKRKVGGLGFLVKER---VSKPPVIISDLIRGGAAEQSGLIQAGDIILAVNGR 70

Query: 613 SLVGLPLATCQGIIKGLKNQTQVKL 637
            LV L   +   +++G+ ++T V L
Sbjct: 71  PLVDLSYDSALEVLRGIASETHVVL 95



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 17/52 (32%), Positives = 31/52 (59%), Gaps = 1/52 (1%)

Query: 667 IICSLMRGGIAERGG-VRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHM 717
           II  L+RGG AE+ G ++ G  I+ +NG+ +V  +++  ++ L     E H+
Sbjct: 42  IISDLIRGGAAEQSGLIQAGDIILAVNGRPLVDLSYDSALEVLRGIASETHV 93


>gi|169213065 PREDICTED: similar to hCG1654128 [Homo sapiens]
          Length = 851

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 67/234 (28%), Positives = 93/234 (39%), Gaps = 29/234 (12%)

Query: 42  VPEGLELAALRPESPAPEEQECHNHSPDGD-SSSDYVNNTSEEEDYDEGLPEEEEGITYY 100
           VP GL            E +     +  GD  +S   ++  +EED  E     E G+   
Sbjct: 27  VPGGLTAGTRIIHLRETERRSSQRRAELGDCDASPTEHDVGQEEDGPEDASPTEHGVDQQ 86

Query: 101 IRYCPEDDSYLE-GMDC-NGEEYLAHSAHPVDTDECQEAVEEWTDSAGPHPHG--HEAEG 156
               PED S  E G++  +G E  + + H VD  E      +  + A P  HG   E +G
Sbjct: 87  -EDGPEDASPTEHGVNQEDGPEDASPTEHGVDQQE------DGPEDARPTEHGIDQEEDG 139

Query: 157 SQDYP------DGQLPIPEDEPSVLEAHDQEEDGHYCASKEGYQDYYPEEANGNTGASPY 210
            +D        D Q   PED        DQEEDG   AS   ++    +E +G   ASP 
Sbjct: 140 PEDASLTEHGVDQQEDGPEDASPTEHGIDQEEDGPEDASPTEHEHGVDQEEDGPEDASP- 198

Query: 211 RLRRGDGDLEDQEEDIDQIVAEIKMSLSMTSITSASEASP-EHG--PEPGPEDS 261
               G     DQEED  +  +  +  +         +A P EHG   E GPED+
Sbjct: 199 -TEHG----VDQEEDGPEDASPTEHGVDQED--GPEDARPTEHGVDQEDGPEDA 245


>gi|122937249 glutamate receptor interacting protein 2 [Homo
           sapiens]
          Length = 1141

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 43/173 (24%), Positives = 77/173 (44%), Gaps = 23/173 (13%)

Query: 557 LQLEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVG 616
           ++L K +G  LG+ +         P V  +N+  GG AARS  L+IGD I S+NG  L  
Sbjct: 146 VELIKKEGSTLGLTISGGTDKDGKPRV--SNLRPGGLAARSDLLNIGDYIRSVNGIHLTR 203

Query: 617 LPLATCQGIIKGLKNQTQVKLNIVSCPPV----TTVLIKRPDLKY-----QLGFSVQNG- 666
           L       ++K +  +  +++     PP       ++ K  D+         GF ++ G 
Sbjct: 204 LRHDEIITLLKNVGERVVLEVEYELPPPAPENNPRIISKTVDVSLYKEGNSFGFVLRGGA 263

Query: 667 ----------IICSLMRGGIAER-GGVRVGHRIIEINGQSVVATAHEKIVQAL 708
                     ++  +  GG A+R G ++VG R++ ++G  +   +H   +  L
Sbjct: 264 HEDGHKSRPLVLTYVRPGGPADREGSLKVGDRLLSVDGIPLHGASHATALATL 316



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 33/155 (21%), Positives = 75/155 (48%), Gaps = 16/155 (10%)

Query: 583 VILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQT--QVKLNIV 640
           ++L  +  GGPA R G L +GD+++S++G  L G   AT    ++   ++   QV+ ++ 
Sbjct: 273 LVLTYVRPGGPADREGSLKVGDRLLSVDGIPLHGASHATALATLRQCSHEALFQVEYDVA 332

Query: 641 -------SCPPVTTVLIKRPDLKYQLGF---SVQNGIICSLMR---GGIAER-GGVRVGH 686
                  +  P+   ++K P     +     S++N  + ++ R     + +R G +  G 
Sbjct: 333 TPDTVANASGPLMVEIVKTPGSALGISLTTTSLRNKSVITIDRIKPASVVDRSGALHPGD 392

Query: 687 RIIEINGQSVVATAHEKIVQALSNSVGEIHMKTMP 721
            I+ I+G S+   +  +  + L++   ++ ++ +P
Sbjct: 393 HILSIDGTSMEHCSLLEATKLLASISEKVRLEILP 427



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 47/206 (22%), Positives = 93/206 (45%), Gaps = 28/206 (13%)

Query: 516 LRANGINPEDLSQKEYSDIINTQEMYNDDLIHFS--------NSENCKELQLEKHKGEIL 567
           L  NGI  ED + +E + ++    + +  ++            S     ++L K +   L
Sbjct: 607 LSINGIATEDGTMEEANQLLRDAALAHKVVLEVEFDVAESVIPSSGTFHVKLPKKRSVEL 666

Query: 568 GVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIK 627
           G+ +  +      P +I++++  G  A R+G L  GD++++I+   L   P+     I++
Sbjct: 667 GITISSASRKRGEP-LIISDIKKGSVAHRTGTLEPGDKLLAIDNIRLDNCPMEDAVQILR 725

Query: 628 GLKNQTQVKL--------NIVSCPPVT-TVLIKRPDLKYQLGFSVQNG-------IICSL 671
             ++  ++K+         + +   V+ TV +KR      LG ++          +I  L
Sbjct: 726 QCEDLVKLKIRKDEDNSDELETTGAVSYTVELKR--YGGPLGITISGTEEPFDPIVISGL 783

Query: 672 MRGGIAER-GGVRVGHRIIEINGQSV 696
            + G+AER G + VG RI+ IN  S+
Sbjct: 784 TKRGLAERTGAIHVGDRILAINNVSL 809



 Score = 38.9 bits (89), Expect = 0.017
 Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 2/60 (3%)

Query: 561 KHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLA 620
           K  G  LG+ +  SG       ++++ +   G A R+G + +GD+I++IN  SL G PL+
Sbjct: 758 KRYGGPLGITI--SGTEEPFDPIVISGLTKRGLAERTGAIHVGDRILAINNVSLKGRPLS 815



 Score = 33.5 bits (75), Expect = 0.73
 Identities = 32/142 (22%), Positives = 60/142 (42%), Gaps = 16/142 (11%)

Query: 593 PAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNI------VSCPPVT 646
           PA R G L +GD+++SING +     +     +++      +V L +         P   
Sbjct: 593 PAERCGLLQVGDRVLSINGIATEDGTMEEANQLLRDAALAHKVVLEVEFDVAESVIPSSG 652

Query: 647 TVLIKRPDLK-YQLGFSVQNG--------IICSLMRGGIAER-GGVRVGHRIIEINGQSV 696
           T  +K P  +  +LG ++ +         II  + +G +A R G +  G +++ I+   +
Sbjct: 653 TFHVKLPKKRSVELGITISSASRKRGEPLIISDIKKGSVAHRTGTLEPGDKLLAIDNIRL 712

Query: 697 VATAHEKIVQALSNSVGEIHMK 718
                E  VQ L      + +K
Sbjct: 713 DNCPMEDAVQILRQCEDLVKLK 734


>gi|45827729 scribble isoform b [Homo sapiens]
          Length = 1630

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 46/155 (29%), Positives = 75/155 (48%), Gaps = 27/155 (17%)

Query: 581  PTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIV 640
            P V ++ ++  G AARSG L +GD+I+++NG  +     AT Q  +  L     ++L+++
Sbjct: 1034 PGVFISKVLPRGLAARSG-LRVGDRILAVNGQDVRD---ATHQEAVSALLRPC-LELSLL 1088

Query: 641  ----SCPPVTTVLIKRPDLKYQLGFSVQNG----------------IICSLMRGGIAERG 680
                  PP    L  +     +LG S++ G                 I  +   G A R 
Sbjct: 1089 VRRDPAPPGLRELCIQKAPGERLGISIRGGARGHAGNPRDPTDEGIFISKVSPTGAAGRD 1148

Query: 681  G-VRVGHRIIEINGQSVVATAHEKIVQALSNSVGE 714
            G +RVG R++E+N QS++   H + VQ L  SVG+
Sbjct: 1149 GRLRVGLRLLEVNQQSLLGLTHGEAVQLL-RSVGD 1182



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 44/187 (23%), Positives = 66/187 (35%), Gaps = 61/187 (32%)

Query: 583  VILANMMNGGPAARSGKLSIGDQIMSINGTSL--------------------------VG 616
            + ++ +  GG A R+G L +GD+++SING  +                           G
Sbjct: 892  IFVSRIAEGGAAHRAGTLQVGDRVLSINGVDVTEARHDHAVSLLTAASPTIALLLEREAG 951

Query: 617  LPL--------------------ATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKRPDLK 656
             PL                     T    + GL +     L      P     I+ P   
Sbjct: 952  GPLPPSPLPHSSPPTAAVATTSITTATPGVPGLPSLAPSLLAAALEGPYPVEEIRLPRAG 1011

Query: 657  YQLGFSVQNG---------------IICSLMRGGIAERGGVRVGHRIIEINGQSVVATAH 701
              LG S+  G                I  ++  G+A R G+RVG RI+ +NGQ V    H
Sbjct: 1012 GPLGLSIVGGSDHSSHPFGVQEPGVFISKVLPRGLAARSGLRVGDRILAVNGQDVRDATH 1071

Query: 702  EKIVQAL 708
            ++ V AL
Sbjct: 1072 QEAVSAL 1078



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 39/180 (21%), Positives = 68/180 (37%), Gaps = 54/180 (30%)

Query: 583 VILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKL---NI 639
           + ++ +   GPAAR+G + +GD+++ +NG +L G         ++G     Q+++    +
Sbjct: 758 IFISRVSEEGPAARAG-VRVGDKLLEVNGVALQGAEHHEAVEALRGAGTAVQMRVWRERM 816

Query: 640 VSCPPVTTVLIKRPDLKYQ------------------------------------LGFSV 663
           V      T+   RP+  Y                                     LGFS+
Sbjct: 817 VEPENAVTITPLRPEDDYSPRERRGGGLRLPLLPPESPGPLRQRHVACLARSERGLGFSI 876

Query: 664 QNG-------------IICSLMRGGIAERGG-VRVGHRIIEINGQSVVATAHEKIVQALS 709
             G              +  +  GG A R G ++VG R++ ING  V    H+  V  L+
Sbjct: 877 AGGKGSTPYRAGDAGIFVSRIAEGGAAHRAGTLQVGDRVLSINGVDVTEARHDHAVSLLT 936



 Score = 37.0 bits (84), Expect = 0.066
 Identities = 16/44 (36%), Positives = 27/44 (61%)

Query: 675 GIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMK 718
           G A R GVRVG +++E+NG ++    H + V+AL  +   + M+
Sbjct: 767 GPAARAGVRVGDKLLEVNGVALQGAEHHEAVEALRGAGTAVQMR 810


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.132    0.383 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,618,428
Number of Sequences: 37866
Number of extensions: 1779853
Number of successful extensions: 6859
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 133
Number of HSP's successfully gapped in prelim test: 212
Number of HSP's that attempted gapping in prelim test: 6002
Number of HSP's gapped (non-prelim): 950
length of query: 737
length of database: 18,247,518
effective HSP length: 110
effective length of query: 627
effective length of database: 14,082,258
effective search space: 8829575766
effective search space used: 8829575766
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press