Guide to the Human Genome
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Search of human proteins with 194272168

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194272168 Mov10, Moloney leukemia virus 10, homolog [Homo
sapiens]
         (1003 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194272168 Mov10, Moloney leukemia virus 10, homolog [Homo sap...  2037   0.0  
gi|14211540 Mov10, Moloney leukemia virus 10, homolog [Homo sapi...  2037   0.0  
gi|14251207 MOV10-like 1 [Homo sapiens]                               423   e-118
gi|54792138 helicase with zinc finger domain [Homo sapiens]           180   7e-45
gi|18375673 regulator of nonsense transcripts 1 [Homo sapiens]        157   5e-38
gi|156105693 PPAR-alpha interacting complex protein 285 isoform ...   117   4e-26
gi|156105695 PPAR-alpha interacting complex protein 285 isoform ...   117   4e-26
gi|119392094 immunoglobulin mu binding protein 2 [Homo sapiens]       115   2e-25
gi|113722133 senataxin [Homo sapiens]                                  92   3e-18
gi|122937299 DNA replication helicase 2 homolog [Homo sapiens]         86   2e-16
gi|28626521 zinc finger, NFX1-type containing 1 [Homo sapiens]         63   1e-09
gi|38788372 aquarius [Homo sapiens]                                    40   0.008
gi|23943900 transmembrane channel-like 8 [Homo sapiens]                33   1.0  
gi|194306571 replication factor C 5 isoform 2 [Homo sapiens]           33   1.8  
gi|194306567 replication factor C 5 isoform 2 [Homo sapiens]           33   1.8  
gi|6677723 replication factor C 5 isoform 1 [Homo sapiens]             33   1.8  
gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]          33   1.8  
gi|52426743 cisplatin resistance-associated overexpressed protei...    33   1.8  
gi|19923485 cisplatin resistance-associated overexpressed protei...    33   1.8  
gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]            32   3.9  
gi|42716289 erythrocyte membrane protein band 4.1 (elliptocytosi...    31   5.1  
gi|42716291 erythrocyte membrane protein band 4.1 (elliptocytosi...    31   5.1  
gi|4758274 erythrocyte membrane protein band 4.1 (elliptocytosis...    31   5.1  
gi|66529203 hypothetical protein LOC57714 [Homo sapiens]               31   5.1  
gi|4758118 death-associated protein 3 [Homo sapiens]                   31   6.7  
gi|16905526 death-associated protein 3 [Homo sapiens]                  31   6.7  
gi|169234742 NACHT and WD repeat domain containing 1 [Homo sapiens]    31   6.7  
gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens]             30   8.7  
gi|10947135 ATP-binding cassette, sub-family F, member 1 isoform...    30   8.7  
gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform...    30   8.7  

>gi|194272168 Mov10, Moloney leukemia virus 10, homolog [Homo sapiens]
          Length = 1003

 Score = 2037 bits (5277), Expect = 0.0
 Identities = 1003/1003 (100%), Positives = 1003/1003 (100%)

Query: 1    MPSKFSCRQLREAGQCFESFLVVRGLDMETDRERLRTIYNRDFKISFGTPAPGFSSMLYG 60
            MPSKFSCRQLREAGQCFESFLVVRGLDMETDRERLRTIYNRDFKISFGTPAPGFSSMLYG
Sbjct: 1    MPSKFSCRQLREAGQCFESFLVVRGLDMETDRERLRTIYNRDFKISFGTPAPGFSSMLYG 60

Query: 61   MKIANLAYVTKTRVRFFRLDRWADVRFPEKRRMKLGSDISKHHKSLLAKIFYDRAEYLHG 120
            MKIANLAYVTKTRVRFFRLDRWADVRFPEKRRMKLGSDISKHHKSLLAKIFYDRAEYLHG
Sbjct: 61   MKIANLAYVTKTRVRFFRLDRWADVRFPEKRRMKLGSDISKHHKSLLAKIFYDRAEYLHG 120

Query: 121  KHGVDVEVQGPHEARDGQLLIRLDLNRKEVLTLRLRNGGTQSVTLTHLFPLCRTPQFAFY 180
            KHGVDVEVQGPHEARDGQLLIRLDLNRKEVLTLRLRNGGTQSVTLTHLFPLCRTPQFAFY
Sbjct: 121  KHGVDVEVQGPHEARDGQLLIRLDLNRKEVLTLRLRNGGTQSVTLTHLFPLCRTPQFAFY 180

Query: 181  NEDQELPCPLGPGECYELHVHCKTSFVGYFPATVLWELLGPGESGSEGAGTFYIARFLAA 240
            NEDQELPCPLGPGECYELHVHCKTSFVGYFPATVLWELLGPGESGSEGAGTFYIARFLAA
Sbjct: 181  NEDQELPCPLGPGECYELHVHCKTSFVGYFPATVLWELLGPGESGSEGAGTFYIARFLAA 240

Query: 241  VAHSPLAAQLKPMTPFKRTRITGNPVVTNRIEEGERPDRAKGYDLELSMALGTYYPPPRL 300
            VAHSPLAAQLKPMTPFKRTRITGNPVVTNRIEEGERPDRAKGYDLELSMALGTYYPPPRL
Sbjct: 241  VAHSPLAAQLKPMTPFKRTRITGNPVVTNRIEEGERPDRAKGYDLELSMALGTYYPPPRL 300

Query: 301  RQLLPMLLQGTSIFTAPKEIAEIKAQLETALKWRNYEVKLRLLLHLEELQMEHDIRHYDL 360
            RQLLPMLLQGTSIFTAPKEIAEIKAQLETALKWRNYEVKLRLLLHLEELQMEHDIRHYDL
Sbjct: 301  RQLLPMLLQGTSIFTAPKEIAEIKAQLETALKWRNYEVKLRLLLHLEELQMEHDIRHYDL 360

Query: 361  ESVPMTWDPVDQNPRLLTLEVPGVTESRPSVLRGDHLFALLSSETHQEDPITYKGFVHKV 420
            ESVPMTWDPVDQNPRLLTLEVPGVTESRPSVLRGDHLFALLSSETHQEDPITYKGFVHKV
Sbjct: 361  ESVPMTWDPVDQNPRLLTLEVPGVTESRPSVLRGDHLFALLSSETHQEDPITYKGFVHKV 420

Query: 421  ELDRVKLSFSMSLLSRFVDGLTFKVNFTFNRQPLRVQHRALELTGRWLLWPMLFPVAPRD 480
            ELDRVKLSFSMSLLSRFVDGLTFKVNFTFNRQPLRVQHRALELTGRWLLWPMLFPVAPRD
Sbjct: 421  ELDRVKLSFSMSLLSRFVDGLTFKVNFTFNRQPLRVQHRALELTGRWLLWPMLFPVAPRD 480

Query: 481  VPLLPSDVKLKLYDRSLESNPEQLQAMRHIVTGTTRPAPYIIFGPPGTGKTVTLVEAIKQ 540
            VPLLPSDVKLKLYDRSLESNPEQLQAMRHIVTGTTRPAPYIIFGPPGTGKTVTLVEAIKQ
Sbjct: 481  VPLLPSDVKLKLYDRSLESNPEQLQAMRHIVTGTTRPAPYIIFGPPGTGKTVTLVEAIKQ 540

Query: 541  VVKHLPKAHILACAPSNSGADLLCQRLRVHLPSSIYRLLAPSRDIRMVPEDIKPCCNWDA 600
            VVKHLPKAHILACAPSNSGADLLCQRLRVHLPSSIYRLLAPSRDIRMVPEDIKPCCNWDA
Sbjct: 541  VVKHLPKAHILACAPSNSGADLLCQRLRVHLPSSIYRLLAPSRDIRMVPEDIKPCCNWDA 600

Query: 601  KKGEYVFPAKKKLQEYRVLITTLITAGRLVSAQFPIDHFTHIFIDEAGHCMEPESLVAIA 660
            KKGEYVFPAKKKLQEYRVLITTLITAGRLVSAQFPIDHFTHIFIDEAGHCMEPESLVAIA
Sbjct: 601  KKGEYVFPAKKKLQEYRVLITTLITAGRLVSAQFPIDHFTHIFIDEAGHCMEPESLVAIA 660

Query: 661  GLMEVKETGDPGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKGPDGY 720
            GLMEVKETGDPGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKGPDGY
Sbjct: 661  GLMEVKETGDPGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKGPDGY 720

Query: 721  DPQFITKLLRNYRSHPTILDIPNQLYYEGELQACADVVDRERFCRWAGLPRQGFPIIFHG 780
            DPQFITKLLRNYRSHPTILDIPNQLYYEGELQACADVVDRERFCRWAGLPRQGFPIIFHG
Sbjct: 721  DPQFITKLLRNYRSHPTILDIPNQLYYEGELQACADVVDRERFCRWAGLPRQGFPIIFHG 780

Query: 781  VMGKDEREGNSPSFFNPEEAATVTSYLKLLLAPSSKKGKARLSPRSVGVISPYRKQVEKI 840
            VMGKDEREGNSPSFFNPEEAATVTSYLKLLLAPSSKKGKARLSPRSVGVISPYRKQVEKI
Sbjct: 781  VMGKDEREGNSPSFFNPEEAATVTSYLKLLLAPSSKKGKARLSPRSVGVISPYRKQVEKI 840

Query: 841  RYCITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLDLDFNLGFLK 900
            RYCITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLDLDFNLGFLK
Sbjct: 841  RYCITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLDLDFNLGFLK 900

Query: 901  NPKRFNVAVTRAKALLIIVGNPLLLGHDPDWKVFLEFCKENGGYTGCPFPAKLDLQQGQN 960
            NPKRFNVAVTRAKALLIIVGNPLLLGHDPDWKVFLEFCKENGGYTGCPFPAKLDLQQGQN
Sbjct: 901  NPKRFNVAVTRAKALLIIVGNPLLLGHDPDWKVFLEFCKENGGYTGCPFPAKLDLQQGQN 960

Query: 961  LLQGLSKLSPSTSGPHSHDYLPQEREGEGGLSLQVEPEWRNEL 1003
            LLQGLSKLSPSTSGPHSHDYLPQEREGEGGLSLQVEPEWRNEL
Sbjct: 961  LLQGLSKLSPSTSGPHSHDYLPQEREGEGGLSLQVEPEWRNEL 1003


>gi|14211540 Mov10, Moloney leukemia virus 10, homolog [Homo sapiens]
          Length = 1003

 Score = 2037 bits (5277), Expect = 0.0
 Identities = 1003/1003 (100%), Positives = 1003/1003 (100%)

Query: 1    MPSKFSCRQLREAGQCFESFLVVRGLDMETDRERLRTIYNRDFKISFGTPAPGFSSMLYG 60
            MPSKFSCRQLREAGQCFESFLVVRGLDMETDRERLRTIYNRDFKISFGTPAPGFSSMLYG
Sbjct: 1    MPSKFSCRQLREAGQCFESFLVVRGLDMETDRERLRTIYNRDFKISFGTPAPGFSSMLYG 60

Query: 61   MKIANLAYVTKTRVRFFRLDRWADVRFPEKRRMKLGSDISKHHKSLLAKIFYDRAEYLHG 120
            MKIANLAYVTKTRVRFFRLDRWADVRFPEKRRMKLGSDISKHHKSLLAKIFYDRAEYLHG
Sbjct: 61   MKIANLAYVTKTRVRFFRLDRWADVRFPEKRRMKLGSDISKHHKSLLAKIFYDRAEYLHG 120

Query: 121  KHGVDVEVQGPHEARDGQLLIRLDLNRKEVLTLRLRNGGTQSVTLTHLFPLCRTPQFAFY 180
            KHGVDVEVQGPHEARDGQLLIRLDLNRKEVLTLRLRNGGTQSVTLTHLFPLCRTPQFAFY
Sbjct: 121  KHGVDVEVQGPHEARDGQLLIRLDLNRKEVLTLRLRNGGTQSVTLTHLFPLCRTPQFAFY 180

Query: 181  NEDQELPCPLGPGECYELHVHCKTSFVGYFPATVLWELLGPGESGSEGAGTFYIARFLAA 240
            NEDQELPCPLGPGECYELHVHCKTSFVGYFPATVLWELLGPGESGSEGAGTFYIARFLAA
Sbjct: 181  NEDQELPCPLGPGECYELHVHCKTSFVGYFPATVLWELLGPGESGSEGAGTFYIARFLAA 240

Query: 241  VAHSPLAAQLKPMTPFKRTRITGNPVVTNRIEEGERPDRAKGYDLELSMALGTYYPPPRL 300
            VAHSPLAAQLKPMTPFKRTRITGNPVVTNRIEEGERPDRAKGYDLELSMALGTYYPPPRL
Sbjct: 241  VAHSPLAAQLKPMTPFKRTRITGNPVVTNRIEEGERPDRAKGYDLELSMALGTYYPPPRL 300

Query: 301  RQLLPMLLQGTSIFTAPKEIAEIKAQLETALKWRNYEVKLRLLLHLEELQMEHDIRHYDL 360
            RQLLPMLLQGTSIFTAPKEIAEIKAQLETALKWRNYEVKLRLLLHLEELQMEHDIRHYDL
Sbjct: 301  RQLLPMLLQGTSIFTAPKEIAEIKAQLETALKWRNYEVKLRLLLHLEELQMEHDIRHYDL 360

Query: 361  ESVPMTWDPVDQNPRLLTLEVPGVTESRPSVLRGDHLFALLSSETHQEDPITYKGFVHKV 420
            ESVPMTWDPVDQNPRLLTLEVPGVTESRPSVLRGDHLFALLSSETHQEDPITYKGFVHKV
Sbjct: 361  ESVPMTWDPVDQNPRLLTLEVPGVTESRPSVLRGDHLFALLSSETHQEDPITYKGFVHKV 420

Query: 421  ELDRVKLSFSMSLLSRFVDGLTFKVNFTFNRQPLRVQHRALELTGRWLLWPMLFPVAPRD 480
            ELDRVKLSFSMSLLSRFVDGLTFKVNFTFNRQPLRVQHRALELTGRWLLWPMLFPVAPRD
Sbjct: 421  ELDRVKLSFSMSLLSRFVDGLTFKVNFTFNRQPLRVQHRALELTGRWLLWPMLFPVAPRD 480

Query: 481  VPLLPSDVKLKLYDRSLESNPEQLQAMRHIVTGTTRPAPYIIFGPPGTGKTVTLVEAIKQ 540
            VPLLPSDVKLKLYDRSLESNPEQLQAMRHIVTGTTRPAPYIIFGPPGTGKTVTLVEAIKQ
Sbjct: 481  VPLLPSDVKLKLYDRSLESNPEQLQAMRHIVTGTTRPAPYIIFGPPGTGKTVTLVEAIKQ 540

Query: 541  VVKHLPKAHILACAPSNSGADLLCQRLRVHLPSSIYRLLAPSRDIRMVPEDIKPCCNWDA 600
            VVKHLPKAHILACAPSNSGADLLCQRLRVHLPSSIYRLLAPSRDIRMVPEDIKPCCNWDA
Sbjct: 541  VVKHLPKAHILACAPSNSGADLLCQRLRVHLPSSIYRLLAPSRDIRMVPEDIKPCCNWDA 600

Query: 601  KKGEYVFPAKKKLQEYRVLITTLITAGRLVSAQFPIDHFTHIFIDEAGHCMEPESLVAIA 660
            KKGEYVFPAKKKLQEYRVLITTLITAGRLVSAQFPIDHFTHIFIDEAGHCMEPESLVAIA
Sbjct: 601  KKGEYVFPAKKKLQEYRVLITTLITAGRLVSAQFPIDHFTHIFIDEAGHCMEPESLVAIA 660

Query: 661  GLMEVKETGDPGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKGPDGY 720
            GLMEVKETGDPGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKGPDGY
Sbjct: 661  GLMEVKETGDPGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKGPDGY 720

Query: 721  DPQFITKLLRNYRSHPTILDIPNQLYYEGELQACADVVDRERFCRWAGLPRQGFPIIFHG 780
            DPQFITKLLRNYRSHPTILDIPNQLYYEGELQACADVVDRERFCRWAGLPRQGFPIIFHG
Sbjct: 721  DPQFITKLLRNYRSHPTILDIPNQLYYEGELQACADVVDRERFCRWAGLPRQGFPIIFHG 780

Query: 781  VMGKDEREGNSPSFFNPEEAATVTSYLKLLLAPSSKKGKARLSPRSVGVISPYRKQVEKI 840
            VMGKDEREGNSPSFFNPEEAATVTSYLKLLLAPSSKKGKARLSPRSVGVISPYRKQVEKI
Sbjct: 781  VMGKDEREGNSPSFFNPEEAATVTSYLKLLLAPSSKKGKARLSPRSVGVISPYRKQVEKI 840

Query: 841  RYCITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLDLDFNLGFLK 900
            RYCITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLDLDFNLGFLK
Sbjct: 841  RYCITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLDLDFNLGFLK 900

Query: 901  NPKRFNVAVTRAKALLIIVGNPLLLGHDPDWKVFLEFCKENGGYTGCPFPAKLDLQQGQN 960
            NPKRFNVAVTRAKALLIIVGNPLLLGHDPDWKVFLEFCKENGGYTGCPFPAKLDLQQGQN
Sbjct: 901  NPKRFNVAVTRAKALLIIVGNPLLLGHDPDWKVFLEFCKENGGYTGCPFPAKLDLQQGQN 960

Query: 961  LLQGLSKLSPSTSGPHSHDYLPQEREGEGGLSLQVEPEWRNEL 1003
            LLQGLSKLSPSTSGPHSHDYLPQEREGEGGLSLQVEPEWRNEL
Sbjct: 961  LLQGLSKLSPSTSGPHSHDYLPQEREGEGGLSLQVEPEWRNEL 1003


>gi|14251207 MOV10-like 1 [Homo sapiens]
          Length = 1211

 Score =  423 bits (1087), Expect = e-118
 Identities = 297/825 (36%), Positives = 425/825 (51%), Gaps = 131/825 (15%)

Query: 232  FYIARFLAAVAHSPLAAQLKPMTPFKRTRITGNPVVTNRIEEGERPDRAKGYDLELSMAL 291
            F I R+L     S   + +    PF   ++  +  +T+         + +    +L   L
Sbjct: 436  FLIGRYLEVNVISGEESLIAAREPFSWKKLKSSQALTSAKTTVVVTAQKRNSRRQLPSFL 495

Query: 292  GTYYPPPRLRQLLPMLLQGTSIFTAPKEIAEIKAQLETALKWRNYEVKLRLLLHLEELQM 351
              Y  P RLR+ +    Q   I T    +AE+       L   NY+ K   LL LEE+  
Sbjct: 496  PQYPIPDRLRKCVE---QKIDILTFQPLLAEL-------LNMSNYKEKFSTLLWLEEIYA 545

Query: 352  EHDIRHYDLESVPMTWDPVDQNPRLLTLEVPGVTESRPSVLRGDHLFALLSSETHQEDPI 411
            E +++ Y++  + +      +N  LL LEVPG+ E RPS+  GD L  +L ++ +    I
Sbjct: 546  EMELKEYNMSGIILR-----RNGDLLVLEVPGLAEGRPSLYAGDKL--ILKTQEYNGHAI 598

Query: 412  TYKGFVHKVELDRVKLSFSMSLLSRFVDGLTFK---VNFTFNRQPLRVQHRAL------- 461
             Y  +V ++  + V L  +      F     F+   V FT+NR   R  H AL       
Sbjct: 599  EYISYVTEIHEEDVTLKIN----PEFEQAYNFEPMDVEFTYNRTTSRRCHFALEHVIHLG 654

Query: 462  --------------ELTGRWLLWPMLFP-------------------------VAPRDVP 482
                          ++TG W                                 V  +D+P
Sbjct: 655  VKVLFPEEIILQSPQVTGNWNHAQDTKSSGQSTSKKNRKTMTDQAEHGTEERRVGDKDLP 714

Query: 483  LL----------------PSDVKLKLYDRSLESNPEQLQAMRHIVTGTTRPAPYIIFGPP 526
            +L                P   K++ ++  L  N  Q  A++ I++G  RP PYI+FGPP
Sbjct: 715  VLAPFTAEMSDWVDEIQTPKARKMEFFNPVLNEN--QKLAVKRILSGDCRPLPYILFGPP 772

Query: 527  GTGKTVTLVEAIKQVVKHLPKAHILACAPSNSGADLLCQRL---RVHLPSSIYRLLAPSR 583
            GTGKTVT++EA+ QV   LP + IL CAPSNS ADL+C RL   +V  P+++ R+ A  R
Sbjct: 773  GTGKTVTIIEAVLQVHFALPDSRILVCAPSNSAADLVCLRLHESKVLQPATMVRVNATCR 832

Query: 584  DIRMVPEDIKPCCNWDAKKGEYVFPAKKKLQEYRVLITTLITAGRLVSAQFPIDHFTHIF 643
               +V + +KP C    + GE ++ A +    +R++ITT  ++G        + HFTH+F
Sbjct: 833  FEEIVIDAVKPYC----RDGEDIWKASR----FRIIITTCSSSGLFYQIGVRVGHFTHVF 884

Query: 644  IDEAGHCMEPESLVAIAGLMEVKETGDPGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLL 703
            +DEAG   EPE L+ + GLM      D  GQ+VLAGDP QLGPV++S L   +GL  S L
Sbjct: 885  VDEAGQASEPECLIPL-GLMS-----DISGQIVLAGDPMQLGPVIKSRLAMAYGLNVSFL 938

Query: 704  ERLLTYNSLYKKGPDGY------DPQFITKLLRNYRSHPTILDIPNQLYYEGELQACADV 757
            ERL++    Y++  + +      +P  +TKL++NYRSH  +L +P++L+Y  EL+ CAD 
Sbjct: 939  ERLMS-RPAYQRDENAFGACGAHNPLLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADP 997

Query: 758  VDRERFCRWAGLPRQGFPIIFHGVMGKDEREGNSPSFFNPEEAATVTSYLKLLLAPSSKK 817
                    W  LP++GFP+IFHGV G + REG SPS+FNP EA  V  Y  LL    S  
Sbjct: 998  TVVTSLLGWEKLPKKGFPLIFHGVRGSEAREGKSPSWFNPAEAVQVLRYCCLLAHSIS-- 1055

Query: 818  GKARLSPRSVGVISPYRKQVEKIRYCITKLDRELRGLDDIKDLKVGSVEEFQGQERSVIL 877
              +++S   +GVI+PYRKQVEKIR  +  +        D+ D+KVGSVEEFQGQE  VI+
Sbjct: 1056 --SQVSASDIGVITPYRKQVEKIRILLRNV--------DLMDIKVGSVEEFQGQEYLVII 1105

Query: 878  ISTVRSSQSFVQLDLDFNLGFLKNPKRFNVAVTRAKALLIIVGNPLLLGHDPDWKVFLEF 937
            ISTVRS++   + D  F LGFL N KRFNVA+TR KALLI++GNP +L  DP +   LE+
Sbjct: 1106 ISTVRSNEDRFEDDRYF-LGFLSNSKRFNVAITRPKALLIVLGNPHVLVRDPCFGALLEY 1164

Query: 938  CKENGGYTGCPFPAKLDLQQGQNLLQGLSKLS----PSTSGPHSH 978
               NG Y GC  P    LQ  QN  +G++  S    P ++GP  H
Sbjct: 1165 SITNGVYMGCDLPPA--LQSLQNCGEGVADPSYPVVPESTGPEKH 1207


>gi|54792138 helicase with zinc finger domain [Homo sapiens]
          Length = 1942

 Score =  180 bits (456), Expect = 7e-45
 Identities = 162/570 (28%), Positives = 266/570 (46%), Gaps = 79/570 (13%)

Query: 444  KVNFTFNRQPLRVQHRALE-LTGRWLLWPMLFPVAPRDVPLLPSDVKLKLYDRSLES--N 500
            ++ F  NR PL   H AL+ +    +L+P +  + P  +P  P+    + +D  L+   N
Sbjct: 590  ELQFQLNRLPLCEMHYALDRIKDNGVLFPDI-SMTPT-IPWSPN----RQWDEQLDPRLN 643

Query: 501  PEQLQAMRHIVTGTT-RPAPYIIFGPPGTGKTVTLVEAIKQVVKHLPKAHILACAPSNSG 559
             +Q +A+  I T    +  P +I GP GTGKT TL +A+K +++   +  IL C  SNS 
Sbjct: 644  AKQKEAVLAITTPLAIQLPPVLIIGPYGTGKTFTLAQAVKHILQQ-QETRILICTHSNSA 702

Query: 560  ADLLCQR-LRVHLPSSI-----YRLLAPSRDIRMVPEDIKPCCNWDAKKGEYVFPAKKKL 613
            ADL  +  L  ++ +        R+   +R ++ V   +   C   +    +  P K+ +
Sbjct: 703  ADLYIKDYLHPYVEAGNPQARPLRVYFRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDI 762

Query: 614  QEYRVLITTLITAGRLVSAQFPIDHFTHIFIDEAGHCMEPESLVAIAGLMEVKETGDPGG 673
             ++RV++ TL T+  L         FTHI +DEA   ME E+++ +A  +  + T     
Sbjct: 763  LKHRVVVVTLNTSQYLCQLDLEPGFFTHILLDEAAQAMECETIMPLA--LATQNT----- 815

Query: 674  QLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKGPDGYDPQFITKLL--RN 731
            ++VLAGD  QL P + S   ++  L  SLL+RL  +          Y  +F  ++L   N
Sbjct: 816  RIVLAGDHMQLSPFVYSEFARERNLHVSLLDRLYEH----------YPAEFPCRILLCEN 865

Query: 732  YRSHPTILDIPNQLYYEGELQACADVVDRERFCRWAGLPRQGFPIIFHGVMGKDEREGNS 791
            YRSH  I++  ++L+YEG+L A       + F          +P+ F    G+D +E NS
Sbjct: 866  YRSHEAIINYTSELFYEGKLMASGKQPAHKDF----------YPLTFFTARGEDVQEKNS 915

Query: 792  PSFFNPEEAATVTSYLKLLLAPSSKKGKARLSPRSVGVISPYRKQVEKIRYCITKLDREL 851
             +F+N  E   V   ++  L         +L   S+GV++PY  QV +IR        EL
Sbjct: 916  TAFYNNAEVFEVVERVE-ELRRKWPVAWGKLDDGSIGVVTPYADQVFRIR-------AEL 967

Query: 852  RGLDDIKDLKVGSVEEFQGQERSVILISTVRS--------------SQSFVQLDLDFNLG 897
            R    + D+ V  V   QG++  V+ +STVR+               Q       D + G
Sbjct: 968  R-KKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDSTEDLDYG 1026

Query: 898  FLKNPKRFNVAVTRAKALLIIVGNPLLLGH----DPDWKVFLEFCKENGGYTGCPFPAKL 953
            FL N K  N A+TRA++L+ +VG+P+ L         W+ F+  C EN    G  F    
Sbjct: 1027 FLSNYKLLNTAITRAQSLVAVVGDPIALCSIGRCRKFWERFIALCHENSSLHGITF---- 1082

Query: 954  DLQQGQNLLQGLSKLSPSTSGPHSHDYLPQ 983
              +Q +  L+ L         P + +++P+
Sbjct: 1083 --EQIKAQLEALELKKTYVLNPLAPEFIPR 1110


>gi|18375673 regulator of nonsense transcripts 1 [Homo sapiens]
          Length = 1118

 Score =  157 bits (397), Expect = 5e-38
 Identities = 141/472 (29%), Positives = 212/472 (44%), Gaps = 80/472 (16%)

Query: 500 NPEQLQAMRHIVTGTTRPAPYIIFGPPGTGKTVTLVEAIKQVVKHLPKAHILACAPSNSG 559
           N  Q+ A++ ++    RP   +I GPPGTGKTVT    +  + +      +L CAPSN  
Sbjct: 472 NHSQVYAVKTVLQ---RPLS-LIQGPPGTGKTVTSATIVYHLARQ-GNGPVLVCAPSNIA 526

Query: 560 ADLLCQRLR----------------VHLPSSIYRLLAPSRDIRMVPE-----DIKPCCNW 598
            D L +++                 +  P S   L    R++  +PE      +K     
Sbjct: 527 VDQLTEKIHQTGLKVVRLCAKSREAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETGE 586

Query: 599 DAKKGEYVFPAKKKLQEYRVLITTLITAGRLVSAQFPI---DHFTHIFIDEAGHCMEPES 655
            +   E  + A K+  E  +L+   +     V A  P      F  I IDE+    EPE 
Sbjct: 587 LSSADEKRYRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPEC 646

Query: 656 LVAIAGLMEVKETGDPGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKK 715
           +V +  ++  K       QL+L GD  QLGPV+      K GL  SL ERL+        
Sbjct: 647 MVPV--VLGAK-------QLILVGDHCQLGPVVMCKKAAKAGLSQSLFERLVVL------ 691

Query: 716 GPDGYDPQFITKLLRNYRSHPTILDIPNQLYYEGELQACADVVDRERFCRWAGLPRQGFP 775
              G  P    +L   YR HP +   P+ ++YEG LQ      DR +       P+   P
Sbjct: 692 ---GIRP---IRLQVQYRMHPALSAFPSNIFYEGSLQNGVTAADRVKKGFDFQWPQPDKP 745

Query: 776 IIFHGVMGKDEREGNSPSFFNPEEAATVTSYLKLLLAPSSKKGKARLSPRSVGVISPYRK 835
           + F+   G++E   +  S+ N  EAA V      LL       KA   P  +G+I+PY  
Sbjct: 746 MFFYVTQGQEEIASSGTSYLNRTEAANVEKITTKLL-------KAGAKPDQIGIITPYEG 798

Query: 836 Q----VEKIRYC---ITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFV 888
           Q    V+ +++     TKL +E+         ++ SV+ FQG+E+  I++S VR+++   
Sbjct: 799 QRSYLVQYMQFSGSLHTKLYQEV---------EIASVDAFQGREKDFIILSCVRANEHQ- 848

Query: 889 QLDLDFNLGFLKNPKRFNVAVTRAKALLIIVGNPLLLGHDPDWKVFLEFCKE 940
                  +GFL +P+R NVA+TRA+  +IIVGNP  L   P W   L + KE
Sbjct: 849 ------GIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLNYYKE 894


>gi|156105693 PPAR-alpha interacting complex protein 285 isoform 1
            [Homo sapiens]
          Length = 2649

 Score =  117 bits (294), Expect = 4e-26
 Identities = 140/524 (26%), Positives = 216/524 (41%), Gaps = 133/524 (25%)

Query: 500  NPEQLQAMRHIVTGTTRPAPY-IIFGPPGTGKTVTLVEAI--------KQVV-------- 542
            NP Q  A+R  +       P+ +I GPPGTGKT+  +  +        +QV         
Sbjct: 2154 NPSQNVAVREALE-----KPFTVIQGPPGTGKTIVGLHIVFWFHKSNQEQVQPGGPPRGE 2208

Query: 543  KHLPKAHILACAPSNSGADLLCQRL--RVHL-PSSIYRLLAPSRD-----------IRMV 588
            K L    IL C PSN   D+L   L  R+ L P  +Y   A + +           +R  
Sbjct: 2209 KRLGGPCILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQAEASEFPVPRVGSRKLLRKS 2268

Query: 589  PEDIKP-------------------------CCNWDAKKGEY------------VFPAKK 611
            P + +P                           +   ++GE             ++ A+K
Sbjct: 2269 PREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGELFSREDLVWYKKVLWEARK 2328

Query: 612  -KLQEYRVLITTLITAGRLVSAQFPIDHFTHIFIDEAGHCMEPESLVAIAGLMEVKETGD 670
             +L  + V++ T   A    SA   I     I +DEAG   EPE+L+ +    + ++   
Sbjct: 2329 FELDRHEVILCTCSCAA---SASLKILDVRQILVDEAGMATEPETLIPLVQFPQAEK--- 2382

Query: 671  PGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKGPDGYDPQFITKLLR 730
                +VL GD +QL PV+++   Q  GL  SL ER       Y +     D Q       
Sbjct: 2383 ----VVLLGDHKQLRPVVKNERLQNLGLDRSLFER-------YHEDAHMLDTQ------- 2424

Query: 731  NYRSHPTILDIPNQLYYEGELQACADVVDRERFCRWAGLPRQGFPIIFHGVMGKDER--- 787
             YR H  I   P+  +Y+ +L+    +         AG  ++  P+IF  V G +     
Sbjct: 2425 -YRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLGHAG--KESCPVIFGHVQGHERSLLV 2481

Query: 788  ---EGNSPSFFNPEEAATVTSYLKLLLAPSSKKGKARLSPRSVGVISPYRKQVEKIRYCI 844
               EGN  S  N EE A V    K L    +      + P+ + V++PY  Q  +I   +
Sbjct: 2482 STDEGNENSKANLEEVAEVVRITKQLTLGRT------VEPQDIAVLTPYNAQASEISKAL 2535

Query: 845  TKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLDLDFN--------- 895
             +        + I  + V S+ + QG E   +L+STVR+     + DLD           
Sbjct: 2536 RR--------EGIAGVAVSSITKSQGSEWRYVLVSTVRTC---AKSDLDQRPTKSWLKKF 2584

Query: 896  LGFLKNPKRFNVAVTRAKALLIIVGNPLLLGHDPDWKVFLEFCK 939
            LGF+ +P + NVAVTRA+  L ++G+ LLL   P W+  L+FC+
Sbjct: 2585 LGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCE 2628



 Score =  114 bits (284), Expect = 6e-25
 Identities = 122/449 (27%), Positives = 205/449 (45%), Gaps = 57/449 (12%)

Query: 516 RPAPYIIFGPPGTGKTVTLVEAIKQVVKHLPKAHILACAPSNSGADLLCQRL------RV 569
           R  P +I+GP GTGKT TL  A  +V++  P+  +L C  +NS AD+  +          
Sbjct: 536 RVPPLLIYGPFGTGKTYTLAMASLEVIRR-PETKVLICTHTNSAADIYIREYFHSHVSGG 594

Query: 570 HLPSSIYRLLAPSRDIRMV-PEDIKPCCNWDAKKGEYVFPAKKKLQEYRVLITTLITAGR 628
           H  ++  R++   R +    P  ++ CC  D ++  +  P + +L  +RV++TT   A  
Sbjct: 595 HPEATPLRVMYTDRPLSQTDPVTLQYCCLTDDRQA-FRPPTRAELARHRVVVTTTSQARE 653

Query: 629 LVSAQFPIDHFTHIFIDEAGHCMEPESLVAIAGLMEVKETGDPGGQLVLAGDPRQLGPVL 688
           L   + P+  F+HI IDEA   +E E+L  +A           G +LVLAGD  Q+ P L
Sbjct: 654 L---RVPVGFFSHILIDEAAQMLECEALTPLA-------YASHGTRLVLAGDHMQVTPRL 703

Query: 689 RSPLTQKHGLGYSLLERLLTYNSLYKKGPDGYDPQFITKLLRNYRSHPTILDIPNQLYYE 748
            S + +     ++LL RL      Y++       Q       NYR    I+   ++ +Y 
Sbjct: 704 FS-VARARAAEHTLLHRLFL---CYQQETHEVARQSRLVFHENYRCTDAIVSFISRHFYV 759

Query: 749 GE---LQACADVVDRERFCRWAGLPRQGFPIIFHGVMGKDEREGNSPSFFNPEEAATVTS 805
            +   + A   V    R           +P++F  V G  +R+ +  S+ N  E A V  
Sbjct: 760 AKGNPIHARGKVPPHPRH----------YPLMFCHVAGSPDRDMSMASWLNLAEIAQVVE 809

Query: 806 YLKLLLA--PSSKKGKARLSPRSVGVISPYRKQVEKIRYCITKLDRELRGLDDIKDLKVG 863
            ++      PS   G+ +   R + V+S +  QV  +R       +ELR   D+  + VG
Sbjct: 810 KVQEAYNTWPSCWGGREQ---RCICVVS-HGAQVSALR-------QELR-RRDLGQVSVG 857

Query: 864 SVEEFQGQERSVILISTVRSSQSFVQLDLDFNLGFLKNPKRFNVAVTRAKALLIIVGNPL 923
           S E   G++  V+++STV + QS +         F  + +  N  +TRA++ L++VG+ +
Sbjct: 858 SFEILPGRQFRVVVLSTVHTCQSLLSPGA-LAPEFFTDARVLNTVLTRAQSQLVVVGDAV 916

Query: 924 LL----GHDPDWKVFLEFCKENGGYTGCP 948
            L         W+ F+  C E   ++ CP
Sbjct: 917 ALCSFGACGKLWESFIRECVER--HSVCP 943


>gi|156105695 PPAR-alpha interacting complex protein 285 isoform 2
            [Homo sapiens]
          Length = 2080

 Score =  117 bits (294), Expect = 4e-26
 Identities = 140/524 (26%), Positives = 216/524 (41%), Gaps = 133/524 (25%)

Query: 500  NPEQLQAMRHIVTGTTRPAPY-IIFGPPGTGKTVTLVEAI--------KQVV-------- 542
            NP Q  A+R  +       P+ +I GPPGTGKT+  +  +        +QV         
Sbjct: 1585 NPSQNVAVREALE-----KPFTVIQGPPGTGKTIVGLHIVFWFHKSNQEQVQPGGPPRGE 1639

Query: 543  KHLPKAHILACAPSNSGADLLCQRL--RVHL-PSSIYRLLAPSRD-----------IRMV 588
            K L    IL C PSN   D+L   L  R+ L P  +Y   A + +           +R  
Sbjct: 1640 KRLGGPCILYCGPSNKSVDVLAGLLLRRMELKPLRVYSEQAEASEFPVPRVGSRKLLRKS 1699

Query: 589  PEDIKP-------------------------CCNWDAKKGEY------------VFPAKK 611
            P + +P                           +   ++GE             ++ A+K
Sbjct: 1700 PREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGELFSREDLVWYKKVLWEARK 1759

Query: 612  -KLQEYRVLITTLITAGRLVSAQFPIDHFTHIFIDEAGHCMEPESLVAIAGLMEVKETGD 670
             +L  + V++ T   A    SA   I     I +DEAG   EPE+L+ +    + ++   
Sbjct: 1760 FELDRHEVILCTCSCAA---SASLKILDVRQILVDEAGMATEPETLIPLVQFPQAEK--- 1813

Query: 671  PGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKGPDGYDPQFITKLLR 730
                +VL GD +QL PV+++   Q  GL  SL ER       Y +     D Q       
Sbjct: 1814 ----VVLLGDHKQLRPVVKNERLQNLGLDRSLFER-------YHEDAHMLDTQ------- 1855

Query: 731  NYRSHPTILDIPNQLYYEGELQACADVVDRERFCRWAGLPRQGFPIIFHGVMGKDER--- 787
             YR H  I   P+  +Y+ +L+    +         AG  ++  P+IF  V G +     
Sbjct: 1856 -YRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLGHAG--KESCPVIFGHVQGHERSLLV 1912

Query: 788  ---EGNSPSFFNPEEAATVTSYLKLLLAPSSKKGKARLSPRSVGVISPYRKQVEKIRYCI 844
               EGN  S  N EE A V    K L    +      + P+ + V++PY  Q  +I   +
Sbjct: 1913 STDEGNENSKANLEEVAEVVRITKQLTLGRT------VEPQDIAVLTPYNAQASEISKAL 1966

Query: 845  TKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLDLDFN--------- 895
             +        + I  + V S+ + QG E   +L+STVR+     + DLD           
Sbjct: 1967 RR--------EGIAGVAVSSITKSQGSEWRYVLVSTVRTC---AKSDLDQRPTKSWLKKF 2015

Query: 896  LGFLKNPKRFNVAVTRAKALLIIVGNPLLLGHDPDWKVFLEFCK 939
            LGF+ +P + NVAVTRA+  L ++G+ LLL   P W+  L+FC+
Sbjct: 2016 LGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCE 2059



 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 106/414 (25%), Positives = 184/414 (44%), Gaps = 56/414 (13%)

Query: 551 LACAPSNSGADLLCQRL------RVHLPSSIYRLLAPSRDIRMV-PEDIKPCCNWDAKKG 603
           ++ +PS S AD+  +          H  ++  R++   R +    P  ++ CC  D ++ 
Sbjct: 1   MSSSPSRSAADIYIREYFHSHVSGGHPEATPLRVMYTDRPLSQTDPVTLQYCCLTDDRQA 60

Query: 604 EYVFPAKKKLQEYRVLITTLITAGRLVSAQFPIDHFTHIFIDEAGHCMEPESLVAIAGLM 663
            +  P + +L  +RV++TT   A  L   + P+  F+HI IDEA   +E E+L  +A   
Sbjct: 61  -FRPPTRAELARHRVVVTTTSQAREL---RVPVGFFSHILIDEAAQMLECEALTPLA--- 113

Query: 664 EVKETGDPGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKGPDGYDPQ 723
                   G +LVLAGD  Q+ P L S + +     ++LL RL      Y++       Q
Sbjct: 114 ----YASHGTRLVLAGDHMQVTPRLFS-VARARAAEHTLLHRLFL---CYQQETHEVARQ 165

Query: 724 FITKLLRNYRSHPTILDIPNQLYYEGE---LQACADVVDRERFCRWAGLPRQGFPIIFHG 780
                  NYR    I+   ++ +Y  +   + A   V    R           +P++F  
Sbjct: 166 SRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPHPRH----------YPLMFCH 215

Query: 781 VMGKDEREGNSPSFFNPEEAATVTSYLKLLLA--PSSKKGKARLSPRSVGVISPYRKQVE 838
           V G  +R+ +  S+ N  E A V   ++      PS   G+ +   R + V+S +  QV 
Sbjct: 216 VAGSPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQ---RCICVVS-HGAQVS 271

Query: 839 KIRYCITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLDLDFNLGF 898
            +R       +ELR   D+  + VGS E   G++  V+++STV + QS +         F
Sbjct: 272 ALR-------QELR-RRDLGQVSVGSFEILPGRQFRVVVLSTVHTCQSLLSPGA-LAPEF 322

Query: 899 LKNPKRFNVAVTRAKALLIIVGNPLLL----GHDPDWKVFLEFCKENGGYTGCP 948
             + +  N  +TRA++ L++VG+ + L         W+ F+  C E   ++ CP
Sbjct: 323 FTDARVLNTVLTRAQSQLVVVGDAVALCSFGACGKLWESFIRECVER--HSVCP 374


>gi|119392094 immunoglobulin mu binding protein 2 [Homo sapiens]
          Length = 993

 Score =  115 bits (289), Expect = 2e-25
 Identities = 122/470 (25%), Positives = 191/470 (40%), Gaps = 94/470 (20%)

Query: 521 IIFGPPGTGKTVTLVEAIKQVVKHLPKAHILACAPSNSGADLLCQRLRVHLPSSIYRLLA 580
           II GPPGTGKT T+VE I Q VK   K  +L CAPSN   D L +RL +     I RL  
Sbjct: 211 IIHGPPGTGKTTTVVEIILQAVKQGLK--VLCCAPSNIAVDNLVERLAL-CKQRILRLGH 267

Query: 581 PSR----------DIRMVPEDIKPCCNWDAKKGEYVFPAKKKLQEYR------------- 617
           P+R          D  +   D         K  + VF   KK Q+ R             
Sbjct: 268 PARLLESIQQHSLDAVLARSDSAQIVADIRKDIDQVFVKNKKTQDKREKSNFRNEIKLLR 327

Query: 618 ---------VLITTLITAGRLVSAQ-----------FPIDHFTHIFIDEAGHCMEPESLV 657
                     ++ +L +A  +++              P  +F  + IDE    +E    +
Sbjct: 328 KELKEREEAAMLESLTSANVVLATNTGASADGPLKLLPESYFDVVVIDECAQALEASCWI 387

Query: 658 AIAGLMEVKETGDPGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKGP 717
            +              + +LAGD +QL P   S      GL  SL+ERL           
Sbjct: 388 PLL----------KARKCILAGDHKQLPPTTVSHKAALAGLSLSLMERLA---------- 427

Query: 718 DGYDPQFITKLLRNYRSHPTILDIPNQLYYEGELQACADVVDR--ERFCRWAGLPRQGFP 775
           + Y  + +  L   YR H  I+   +   Y G+L A + V           A     G P
Sbjct: 428 EEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAATEETGVP 487

Query: 776 IIFHGVMGK---DEREGNSPSFFNPEEAATVTSYLKLLLAPSSKKGKARLSPRSVGVISP 832
           ++     G    +  E +  S  NP E   V+ +++ L+        A +  R + V+SP
Sbjct: 488 LLLVDTAGCGLFELEEEDEQSKGNPGEVRLVSLHIQALV-------DAGVPARDIAVVSP 540

Query: 833 YRKQVEKIRYCITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLDL 892
           Y  QV+ +R  +     EL         ++ SV+ FQG+E+  +++S VRS++       
Sbjct: 541 YNLQVDLLRQSLVHRHPEL---------EIKSVDGFQGREKEAVILSFVRSNRKG----- 586

Query: 893 DFNLGFLKNPKRFNVAVTRAKALLIIVGNPLLLGHDPDWKVFLEFCKENG 942
              +GFL   +R NVAVTRA+  + ++ +   + +    K  +E+  ++G
Sbjct: 587 --EVGFLAEDRRINVAVTRARRHVAVICDSRTVNNHAFLKTLVEYFTQHG 634


>gi|113722133 senataxin [Homo sapiens]
          Length = 2677

 Score = 91.7 bits (226), Expect = 3e-18
 Identities = 87/339 (25%), Positives = 152/339 (44%), Gaps = 51/339 (15%)

Query: 615  EYRVLITTLITAGRLV-----SAQFPIDHFTHIFIDEAGHCMEPESLVAIAGLMEVKETG 669
            E  ++  TL T+G L+       Q  +  F+ + +DEAG   E E+L  +          
Sbjct: 2147 ESHIICCTLSTSGGLLLESAFRGQGGVP-FSCVIVDEAGQSCEIETLTPLIHRCN----- 2200

Query: 670  DPGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLER---LLTYN---SLYKKGPDGYDPQ 723
                +L+L GDP+QL P + S   Q++G   S++ R   LL  N   ++  + P      
Sbjct: 2201 ----KLILVGDPKQLPPTVISMKAQEYGYDQSMMARFCRLLEENVEHNMISRLP------ 2250

Query: 724  FITKLLRNYRSHPTILDIPNQLYYEGELQACADVVDRERFCRWAGLPRQGFPIIFHGVMG 783
             I +L   YR HP I   P+   Y   L+             W   P   F +      G
Sbjct: 2251 -ILQLTVQYRMHPDICLFPSNYVYNRNLKTNRQTEAIRCSSDWPFQPYLVFDV------G 2303

Query: 784  KDEREGNSPSFFNPEEAATVTSYLKLLLAPSSKKGKARLSPRSVGVISPYRKQVEKIRYC 843
                  ++ S+ N +E   V   +KL+     K  +  +S R++G+I+ Y+ Q   I+  
Sbjct: 2304 DGSERRDNDSYINVQEIKLVMEIIKLI-----KDKRKDVSFRNIGIITHYKAQKTMIQ-- 2356

Query: 844  ITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLDLDFNLGFLKNPK 903
               LD+E    D     +V +V+ FQG+++  ++++ VR++       +  ++GFL + +
Sbjct: 2357 -KDLDKEF---DRKGPAEVDTVDAFQGRQKDCVIVTCVRANS------IQGSIGFLASLQ 2406

Query: 904  RFNVAVTRAKALLIIVGNPLLLGHDPDWKVFLEFCKENG 942
            R NV +TRAK  L I+G+   L  +  W   ++  ++ G
Sbjct: 2407 RLNVTITRAKYSLFILGHLRTLMENQHWNQLIQDAQKRG 2445



 Score = 35.8 bits (81), Expect = 0.21
 Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 14/61 (22%)

Query: 521  IIFGPPGTGKTVTLVEAI-KQVVKHLPKAH-------------ILACAPSNSGADLLCQR 566
            +I GPPGTGK+ T+V  + + + ++  K H             +L CAPSN+  D L ++
Sbjct: 1960 LIHGPPGTGKSKTIVGLLYRLLTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKK 2019

Query: 567  L 567
            +
Sbjct: 2020 I 2020


>gi|122937299 DNA replication helicase 2 homolog [Homo sapiens]
          Length = 1146

 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 111/455 (24%), Positives = 196/455 (43%), Gaps = 66/455 (14%)

Query: 483  LLPSDVKLKLYDRSLESNPEQLQAMRHIVTGTTRPAPYIIFGPPGTGKTVTLVEAIKQVV 542
            +LP D K  +       N  Q QAM+ ++         +I G PGTGKT T+   ++  +
Sbjct: 696  VLPHDAKDTVACILKGLNKPQRQAMKKVLLSKDYT---LIVGMPGTGKTTTICTLVR--I 750

Query: 543  KHLPKAHILACAPSNSGADLLCQRLRVHLPSSIYRLLAPSRDIRMVPEDIKPCCNWDAKK 602
             +     +L  + ++S  D +  +L         RL      I+ V   I+     +  +
Sbjct: 751  LYACGFSVLLTSYTHSAVDNILLKL-AKFKIGFLRL----GQIQKVHPAIQQFTEQEICR 805

Query: 603  GEYVFPAKKKLQEYRVLITTLITAGRLVSAQFPIDHFTHIFIDEAGHCMEPESLVAIAGL 662
             + +       + Y   +    T   +    F    F    +DEA    +P   + +  L
Sbjct: 806  SKSIKSLALLEELYNSQLIVATTCMGINHPIFSRKIFDFCIVDEASQISQP---ICLGPL 862

Query: 663  MEVKETGDPGGQLVLAGDPRQLGPVLRSPLTQKHGLGYSLLERLLTYNSLYKKGPDGYDP 722
               +       + VL GD +QL P++ +   +  G+  SL +RL    S           
Sbjct: 863  FFSR-------RFVLVGDHQQLPPLVLNREARALGMSESLFKRLEQNKSA---------- 905

Query: 723  QFITKLLRNYRSHPTILDIPNQLYYEGELQACADVVDRE----RFCRWAGLPRQGFPIIF 778
              + +L   YR +  I+ + N+L YEG+L+  +D V       R  +   L  + +    
Sbjct: 906  --VVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLELEFYADYS 963

Query: 779  HGVMGKDEREGNSPSFF-------NPEEA-----ATVTSYLKLLLAPSSKKGKARLSPRS 826
                     E N+P  F        PE+      + VT   KL++  +S   KA  SP  
Sbjct: 964  DNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTE-AKLIVFLTSIFVKAGCSPSD 1022

Query: 827  VGVISPYRKQVEKIRYCITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQS 886
            +G+I+PYR+Q++ I   + +          I  ++V +V+++QG+++S++L+S VRS++ 
Sbjct: 1023 IGIIAPYRQQLKIINDLLAR---------SIGMVEVNTVDKYQGRDKSIVLVSFVRSNK- 1072

Query: 887  FVQLDLDFNLG-FLKNPKRFNVAVTRAKALLIIVG 920
                  D  +G  LK+ +R NVA+TRAK  LI++G
Sbjct: 1073 ------DGTVGELLKDWRRLNVAITRAKHKLILLG 1101


>gi|28626521 zinc finger, NFX1-type containing 1 [Homo sapiens]
          Length = 1918

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 72/301 (23%), Positives = 126/301 (41%), Gaps = 51/301 (16%)

Query: 642  IFIDEAGHCMEPESLVAIAGLMEVKETGDPGGQLVLAGDPRQLGPVLRS-PLTQKHGLGY 700
            + ++EA   +E  ++  ++   +          L+L GD +QL P      L +   L  
Sbjct: 1003 VIVEEAAEVLEAHTIATLSKACQ---------HLILIGDHQQLRPSANVYDLAKNFNLEV 1053

Query: 701  SLLERLLTYNSLYKKGPDGYDPQFITKLLRNYRSHPTILDIPNQLYYEGELQACADVVDR 760
            SL ERL+  N  +             +L   +R  P I  +     Y+ +L+    V+  
Sbjct: 1054 SLFERLVKVNIPF------------VRLNYQHRMCPEIARLLTPHIYQ-DLENHPSVLKY 1100

Query: 761  ERFCRWAGLPRQGFPIIFHGVMGKDEREGNSPSFFNPEEAATVTSYLKLLLAPSSKKGKA 820
            E+     G+    F  + H    ++ +EG S    N  EA  V    K  L         
Sbjct: 1101 EKI---KGVSSNLF-FVEHNFPEQEIQEGKSHQ--NQHEAHFVVELCKYFLCQE------ 1148

Query: 821  RLSPRSVGVISPYRKQVEKIRYCITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILIST 880
               P  + +++ Y  Q+    +C+    R+L        ++V  V+++QG+E  +IL+S 
Sbjct: 1149 -YLPSQITILTTYTGQL----FCL----RKLMPAKTFAGVRVHVVDKYQGEENDIILLSL 1199

Query: 881  VRSSQSFVQLDLDFNLGFLKNPKRFNVAVTRAKALLIIVGNPLLLGHDPDWKVFLEFCKE 940
            VRS+Q       +  +GFL+   R  VA++RAK  +  +GN  +L   P W   +   +E
Sbjct: 1200 VRSNQ-------EGKVGFLQISNRICVALSRAKKGMYCIGNMQMLAKVPLWSKIIHTLRE 1252

Query: 941  N 941
            N
Sbjct: 1253 N 1253


>gi|38788372 aquarius [Homo sapiens]
          Length = 1485

 Score = 40.4 bits (93), Expect = 0.008
 Identities = 72/286 (25%), Positives = 121/286 (42%), Gaps = 44/286 (15%)

Query: 639  FTHIFIDEAGHCMEPESLVAIAGLMEVKETGDPGGQLVLAGDPRQLGPVLRSPLTQKHGL 698
            + +I ++EA   +E E+ + +  L   ++      + ++ GD  QL PV+++   QK   
Sbjct: 1056 YDNILMEEAAQILEIETFIPLL-LQNPQDGFSRLKRWIMIGDHHQLPPVIKNMAFQK--- 1111

Query: 699  GYSLLERLLTYNSLYKKGPDGYDPQFITKLLRNYRSHPTILDIPNQLYYE-GELQACADV 757
             YS +E+ L +    + G    D      L    R+  ++ ++ N  Y   G L     +
Sbjct: 1112 -YSNMEQSL-FTRFVRVGVPTVD------LDAQGRARASLCNLYNWRYKNLGNLPHVQLL 1163

Query: 758  VDRERFCRWAGLPRQGFPIIFHGVMGKDEREGNSPSFFNPEEAATVTS---YLKLLLAPS 814
               E     AGL      I      G  E E N   + N  EA  V +   Y+ LL  P+
Sbjct: 1164 P--EFSTANAGLLYDFQLINVEDFQGVGESEPNPYFYQNLGEAEYVVALFMYMCLLGYPA 1221

Query: 815  SKKGKARLSPRSVGVISPYRKQVEKIRYCITKL--DRELRGLDDIKDLKVGSVEEFQGQE 872
             K          + +++ Y  Q   IR  I +   +  L G  +    KV +V+ FQGQ+
Sbjct: 1222 DK----------ISILTTYNGQKHLIRDIINRRCGNNPLIGRPN----KVTTVDRFQGQQ 1267

Query: 873  RSVILISTVRSSQSFVQLDLDFNLGFLKNPKRFNVAVTRAKALLII 918
               IL+S VR+            +G L++ +R  VA++RA+  L I
Sbjct: 1268 NDYILLSLVRTRA----------VGHLRDVRRLVVAMSRARLGLYI 1303



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 19/65 (29%), Positives = 33/65 (50%), Gaps = 4/65 (6%)

Query: 503 QLQAMRHIVTGTTRPAPYIIFGPPGTGKTVTLVEAIKQVVKHLPKAHILACAPSNSGADL 562
           Q++A+R       +P   ++ GPPGTGKT   V+ I  +  + P+   L    SN   + 
Sbjct: 806 QIEAIR----AGMQPGLTMVVGPPGTGKTDVAVQIISNIYHNFPEQRTLIVTHSNQALNQ 861

Query: 563 LCQRL 567
           L +++
Sbjct: 862 LFEKI 866


>gi|23943900 transmembrane channel-like 8 [Homo sapiens]
          Length = 726

 Score = 33.5 bits (75), Expect = 1.0
 Identities = 32/97 (32%), Positives = 45/97 (46%), Gaps = 9/97 (9%)

Query: 299 RLRQLLPMLLQGTSIFTAPKEIAEIKAQLETALKWRNYEVKLRLLLHLEELQMEHDIRHY 358
           RLR+    L +G  ++     + EI     T +  R+Y   LR LL L  L +   +   
Sbjct: 76  RLREAAQRLARGLGLWEGA--LYEIGGLFGTGI--RSYFTFLRFLLLLNLLSL---LLTA 128

Query: 359 DLESVPMTW-DPVDQNPRL-LTLEVPGVTESRPSVLR 393
               +P+ W  P D  P L LTL+ PG  +S P VLR
Sbjct: 129 SFVLLPLVWLRPPDPGPTLNLTLQCPGSRQSPPGVLR 165


>gi|194306571 replication factor C 5 isoform 2 [Homo sapiens]
          Length = 319

 Score = 32.7 bits (73), Expect = 1.8
 Identities = 12/23 (52%), Positives = 18/23 (78%)

Query: 521 IIFGPPGTGKTVTLVEAIKQVVK 543
           +++GPPGTGKT T++   KQ+ K
Sbjct: 36  LLYGPPGTGKTSTILACAKQLYK 58


>gi|194306567 replication factor C 5 isoform 2 [Homo sapiens]
          Length = 319

 Score = 32.7 bits (73), Expect = 1.8
 Identities = 12/23 (52%), Positives = 18/23 (78%)

Query: 521 IIFGPPGTGKTVTLVEAIKQVVK 543
           +++GPPGTGKT T++   KQ+ K
Sbjct: 36  LLYGPPGTGKTSTILACAKQLYK 58


>gi|6677723 replication factor C 5 isoform 1 [Homo sapiens]
          Length = 340

 Score = 32.7 bits (73), Expect = 1.8
 Identities = 12/23 (52%), Positives = 18/23 (78%)

Query: 521 IIFGPPGTGKTVTLVEAIKQVVK 543
           +++GPPGTGKT T++   KQ+ K
Sbjct: 57  LLYGPPGTGKTSTILACAKQLYK 79


>gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]
          Length = 4646

 Score = 32.7 bits (73), Expect = 1.8
 Identities = 15/39 (38%), Positives = 23/39 (58%), Gaps = 3/39 (7%)

Query: 504  LQAMRH---IVTGTTRPAPYIIFGPPGTGKTVTLVEAIK 539
            L  +RH   + T      P ++ GPPG+GKT+TL  A++
Sbjct: 2572 LDTVRHEALLYTWLAEHKPLVLCGPPGSGKTMTLFSALR 2610


>gi|52426743 cisplatin resistance-associated overexpressed protein
           [Homo sapiens]
          Length = 432

 Score = 32.7 bits (73), Expect = 1.8
 Identities = 31/97 (31%), Positives = 47/97 (48%), Gaps = 17/97 (17%)

Query: 806 YLKLLLAPSSKK---GKARLS----PRSVGVISPYRKQVEKIRYCITKLDRELRGLDDIK 858
           YL+ LLA   ++   G ARL+     +S G   P  K  EKI+    K+D  L+ ++++ 
Sbjct: 88  YLQSLLAEVERRIRRGHARLALSQNQQSSGAAGPTGKNEEKIQVLTDKIDVLLQQIEELG 147

Query: 859 DLKVGSVEEFQG--------QERSVILISTVRSSQSF 887
               G VEE QG        +E   +L ST  + +SF
Sbjct: 148 --SEGKVEEAQGMMKLVEQLKEERELLRSTTSTIESF 182


>gi|19923485 cisplatin resistance-associated overexpressed protein
           [Homo sapiens]
          Length = 432

 Score = 32.7 bits (73), Expect = 1.8
 Identities = 31/97 (31%), Positives = 47/97 (48%), Gaps = 17/97 (17%)

Query: 806 YLKLLLAPSSKK---GKARLS----PRSVGVISPYRKQVEKIRYCITKLDRELRGLDDIK 858
           YL+ LLA   ++   G ARL+     +S G   P  K  EKI+    K+D  L+ ++++ 
Sbjct: 88  YLQSLLAEVERRIRRGHARLALSQNQQSSGAAGPTGKNEEKIQVLTDKIDVLLQQIEELG 147

Query: 859 DLKVGSVEEFQG--------QERSVILISTVRSSQSF 887
               G VEE QG        +E   +L ST  + +SF
Sbjct: 148 --SEGKVEEAQGMMKLVEQLKEERELLRSTTSTIESF 182


>gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]
          Length = 980

 Score = 31.6 bits (70), Expect = 3.9
 Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 3/58 (5%)

Query: 503 QLQAMRHIVTGTTRPAPYIIFGPPGTGKTVTLVEAIKQVVKHLPKAHILACAPSNSGA 560
           +LQ    ++TGT+     ++ GPPG GKT  +  A   +  HL K    +    +SGA
Sbjct: 452 RLQPGGALLTGTSS---VLLRGPPGCGKTTVVAAACSHLGLHLLKVPCSSLCAESSGA 506


>gi|42716289 erythrocyte membrane protein band 4.1 (elliptocytosis
           1, RH-linked) isoform 1 [Homo sapiens]
          Length = 775

 Score = 31.2 bits (69), Expect = 5.1
 Identities = 36/129 (27%), Positives = 59/129 (45%), Gaps = 18/129 (13%)

Query: 795 FNPEEAATVTS-----YLKLLLAPSSKKGKARLSPRSVGVISPYRKQVEKIRYCITKLDR 849
           F P + A +T      YL L L      G+   S  ++ ++  Y  Q E   Y     D 
Sbjct: 253 FYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDY-----DP 307

Query: 850 ELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLDLDFNLGFLKNPKR---FN 906
           EL G+D + D K+   +  + +E+ + L  + R S +  Q DL+    FL+N K+   + 
Sbjct: 308 ELHGVDYVSDFKLAPNQTKELEEKVMELHKSYR-SMTPAQADLE----FLENAKKLSMYG 362

Query: 907 VAVTRAKAL 915
           V + +AK L
Sbjct: 363 VDLHKAKDL 371


>gi|42716291 erythrocyte membrane protein band 4.1 (elliptocytosis
           1, RH-linked) isoform 2 [Homo sapiens]
          Length = 641

 Score = 31.2 bits (69), Expect = 5.1
 Identities = 36/129 (27%), Positives = 59/129 (45%), Gaps = 18/129 (13%)

Query: 795 FNPEEAATVTS-----YLKLLLAPSSKKGKARLSPRSVGVISPYRKQVEKIRYCITKLDR 849
           F P + A +T      YL L L      G+   S  ++ ++  Y  Q E   Y     D 
Sbjct: 79  FYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDY-----DP 133

Query: 850 ELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLDLDFNLGFLKNPKR---FN 906
           EL G+D + D K+   +  + +E+ + L  + R S +  Q DL+    FL+N K+   + 
Sbjct: 134 ELHGVDYVSDFKLAPNQTKELEEKVMELHKSYR-SMTPAQADLE----FLENAKKLSMYG 188

Query: 907 VAVTRAKAL 915
           V + +AK L
Sbjct: 189 VDLHKAKDL 197


>gi|4758274 erythrocyte membrane protein band 4.1 (elliptocytosis 1,
           RH-linked) isoform 3 [Homo sapiens]
          Length = 588

 Score = 31.2 bits (69), Expect = 5.1
 Identities = 36/129 (27%), Positives = 59/129 (45%), Gaps = 18/129 (13%)

Query: 795 FNPEEAATVTS-----YLKLLLAPSSKKGKARLSPRSVGVISPYRKQVEKIRYCITKLDR 849
           F P + A +T      YL L L      G+   S  ++ ++  Y  Q E   Y     D 
Sbjct: 79  FYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDY-----DP 133

Query: 850 ELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLDLDFNLGFLKNPKR---FN 906
           EL G+D + D K+   +  + +E+ + L  + R S +  Q DL+    FL+N K+   + 
Sbjct: 134 ELHGVDYVSDFKLAPNQTKELEEKVMELHKSYR-SMTPAQADLE----FLENAKKLSMYG 188

Query: 907 VAVTRAKAL 915
           V + +AK L
Sbjct: 189 VDLHKAKDL 197


>gi|66529203 hypothetical protein LOC57714 [Homo sapiens]
          Length = 1063

 Score = 31.2 bits (69), Expect = 5.1
 Identities = 51/188 (27%), Positives = 79/188 (42%), Gaps = 19/188 (10%)

Query: 267 VTNRIEEGERPDRAKGYDLELSMALGTYYP------PPRLRQLLPMLLQGTSIFTAPKEI 320
           V N I +G R D  KG  +  ++ L + +          L        Q   +   P  I
Sbjct: 510 VMNHITDGPRKDLVKGKQIAAALMLDSTFSILQTWDTINLNSFFTQFEQFCFVLQQPM-I 568

Query: 321 AEIKAQLETALKWRNYEVKLRLLLHLEELQMEHDIRHYDLESVPMTWDPVD--QNPRLLT 378
            E +AQL T L++R  EVK  L  HL+    +H +   D +S      PVD     +L T
Sbjct: 569 YEGQAQLWTDLQYREKEVKRYLWQHLK----KHVVPLPDGKSTDFL--PVDCPVRSKLKT 622

Query: 379 -LEVPGVTESRPSVLRG--DHLFALLSSETHQEDPITYKGFVHKVELDRVKLSFSMSLLS 435
            L V  V E    +L G  D L  LL+S+    D   ++   H + + +    + ++L  
Sbjct: 623 GLIVLFVVEKIELLLEGSLDWLCHLLTSDASSPDEF-HRDLSHILGIPQSWRLYLVNLCQ 681

Query: 436 RFVDGLTF 443
           R +D  T+
Sbjct: 682 RCMDTRTY 689


>gi|4758118 death-associated protein 3 [Homo sapiens]
          Length = 398

 Score = 30.8 bits (68), Expect = 6.7
 Identities = 15/37 (40%), Positives = 24/37 (64%), Gaps = 6/37 (16%)

Query: 520 YIIFGPPGTGKTVTLVEAI----KQ--VVKHLPKAHI 550
           Y+++G  GTGKT++L   I    KQ  ++ H+P AH+
Sbjct: 124 YLLYGEKGTGKTLSLCHVIHFCAKQDWLILHIPDAHL 160


>gi|16905526 death-associated protein 3 [Homo sapiens]
          Length = 398

 Score = 30.8 bits (68), Expect = 6.7
 Identities = 15/37 (40%), Positives = 24/37 (64%), Gaps = 6/37 (16%)

Query: 520 YIIFGPPGTGKTVTLVEAI----KQ--VVKHLPKAHI 550
           Y+++G  GTGKT++L   I    KQ  ++ H+P AH+
Sbjct: 124 YLLYGEKGTGKTLSLCHVIHFCAKQDWLILHIPDAHL 160


>gi|169234742 NACHT and WD repeat domain containing 1 [Homo sapiens]
          Length = 1429

 Score = 30.8 bits (68), Expect = 6.7
 Identities = 14/41 (34%), Positives = 24/41 (58%), Gaps = 2/41 (4%)

Query: 505 QAMRHIVTGTTRPAPYIIFGPPGTGKTVTLVEAIKQVVKHL 545
           Q +RH    + +  P ++FGPPG GKT  + +  +Q+ + L
Sbjct: 189 QQLRH--DDSKQHTPLVLFGPPGIGKTALMCKLAEQMPRLL 227


>gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens]
          Length = 406

 Score = 30.4 bits (67), Expect = 8.7
 Identities = 13/33 (39%), Positives = 21/33 (63%), Gaps = 5/33 (15%)

Query: 500 NPEQLQAMRHIVTGTTRPAPYIIFGPPGTGKTV 532
           +PE  +A+     G  +P   +++GPPGTGKT+
Sbjct: 171 HPELFEAL-----GIAQPKGVLLYGPPGTGKTL 198


>gi|10947135 ATP-binding cassette, sub-family F, member 1 isoform b
           [Homo sapiens]
          Length = 807

 Score = 30.4 bits (67), Expect = 8.7
 Identities = 20/68 (29%), Positives = 29/68 (42%), Gaps = 4/68 (5%)

Query: 486 SDVKLKLYDRSLESNPEQLQAMRHIVTGTTRPAPYIIFGPPGTGKTVTLVEAIKQVVKHL 545
           SD+KL+ +  S       + A  +IV G      Y + GP G GKT  L     + +   
Sbjct: 264 SDIKLEKFSISAHGKELFVNADLYIVAGRR----YGLVGPNGKGKTTLLKHIANRALSIP 319

Query: 546 PKAHILAC 553
           P   +L C
Sbjct: 320 PNIDVLLC 327


>gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform a
           [Homo sapiens]
          Length = 845

 Score = 30.4 bits (67), Expect = 8.7
 Identities = 20/68 (29%), Positives = 29/68 (42%), Gaps = 4/68 (5%)

Query: 486 SDVKLKLYDRSLESNPEQLQAMRHIVTGTTRPAPYIIFGPPGTGKTVTLVEAIKQVVKHL 545
           SD+KL+ +  S       + A  +IV G      Y + GP G GKT  L     + +   
Sbjct: 302 SDIKLEKFSISAHGKELFVNADLYIVAGRR----YGLVGPNGKGKTTLLKHIANRALSIP 357

Query: 546 PKAHILAC 553
           P   +L C
Sbjct: 358 PNIDVLLC 365


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.139    0.423 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,450,859
Number of Sequences: 37866
Number of extensions: 2025924
Number of successful extensions: 4440
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 4354
Number of HSP's gapped (non-prelim): 53
length of query: 1003
length of database: 18,247,518
effective HSP length: 112
effective length of query: 891
effective length of database: 14,006,526
effective search space: 12479814666
effective search space used: 12479814666
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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