Guide to the Human Genome
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Search of human proteins with 190360566

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|190360566 protein-L-isoaspartate (D-aspartate)
O-methyltransferase domain containing 1 [Homo sapiens]
         (357 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|190360566 protein-L-isoaspartate (D-aspartate) O-methyltransf...   726   0.0  
gi|157388995 protein-L-isoaspartate (D-aspartate) O-methyltransf...   488   e-138
gi|157388997 protein-L-isoaspartate (D-aspartate) O-methyltransf...   435   e-122
gi|239757983 PREDICTED: similar to protein-L-isoaspartate (D-asp...   238   6e-63
gi|239747889 PREDICTED: hypothetical protein XP_002346467 [Homo ...   238   6e-63
gi|239752574 PREDICTED: hypothetical protein XP_002348296 [Homo ...   229   4e-60
gi|239758102 PREDICTED: similar to protein-L-isoaspartate (D-asp...   227   1e-59
gi|239756570 PREDICTED: similar to protein-L-isoaspartate (D-asp...   214   1e-55
gi|239752577 PREDICTED: hypothetical protein XP_002348294 [Homo ...   214   1e-55
gi|239745549 PREDICTED: hypothetical protein XP_002343514 [Homo ...   214   1e-55
gi|226530908 protein-L-isoaspartate (D-aspartate) O-methyltransf...    60   2e-09
gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo ...    39   0.007
gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo ...    39   0.007
gi|115511012 coiled-coil domain containing 136 [Homo sapiens]          39   0.007
gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens]         39   0.007
gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo sap...    37   0.035
gi|118600967 shroom family member 4 [Homo sapiens]                     35   0.079
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    35   0.079
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           35   0.10 
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           35   0.10 
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    35   0.13 
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    35   0.13 
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex...    35   0.13 
gi|5454156 ubiquitin specific protease 16 isoform a [Homo sapiens]     33   0.30 
gi|75992941 ubiquitin specific protease 16 isoform a [Homo sapiens]    33   0.30 
gi|38788333 remodeling and spacing factor 1 [Homo sapiens]             33   0.30 
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi...    33   0.30 
gi|56676330 HP1-BP74 [Homo sapiens]                                    33   0.30 
gi|62241003 cardiomyopathy associated 5 [Homo sapiens]                 33   0.30 
gi|50312664 ubiquitin specific protease 16 isoform b [Homo sapiens]    33   0.39 

>gi|190360566 protein-L-isoaspartate (D-aspartate)
           O-methyltransferase domain containing 1 [Homo sapiens]
          Length = 357

 Score =  726 bits (1875), Expect = 0.0
 Identities = 357/357 (100%), Positives = 357/357 (100%)

Query: 1   MGGAVSAGEDNDDLIDNLKEAQYIRTERVEQAFRAIDRGDYYLEGYRDNAYKDLAWKHGN 60
           MGGAVSAGEDNDDLIDNLKEAQYIRTERVEQAFRAIDRGDYYLEGYRDNAYKDLAWKHGN
Sbjct: 1   MGGAVSAGEDNDDLIDNLKEAQYIRTERVEQAFRAIDRGDYYLEGYRDNAYKDLAWKHGN 60

Query: 61  IHLSAPCIYSEVMEALKLQPGLSFLNLGSGTGYLSTMVGLILGPFGINHGIELHSDVVEY 120
           IHLSAPCIYSEVMEALKLQPGLSFLNLGSGTGYLSTMVGLILGPFGINHGIELHSDVVEY
Sbjct: 61  IHLSAPCIYSEVMEALKLQPGLSFLNLGSGTGYLSTMVGLILGPFGINHGIELHSDVVEY 120

Query: 121 AKEKLESFIKNSDSFDKFEFCEPAFVVGNCLQIASDSHQYDRIYCGAGVQKDHENYMKIL 180
           AKEKLESFIKNSDSFDKFEFCEPAFVVGNCLQIASDSHQYDRIYCGAGVQKDHENYMKIL
Sbjct: 121 AKEKLESFIKNSDSFDKFEFCEPAFVVGNCLQIASDSHQYDRIYCGAGVQKDHENYMKIL 180

Query: 181 LKVGGILVMPIEDQLTQIMRTGQNTWESKNILAVSFAPLVQPSKNDNGKPDSVGLPPCAV 240
           LKVGGILVMPIEDQLTQIMRTGQNTWESKNILAVSFAPLVQPSKNDNGKPDSVGLPPCAV
Sbjct: 181 LKVGGILVMPIEDQLTQIMRTGQNTWESKNILAVSFAPLVQPSKNDNGKPDSVGLPPCAV 240

Query: 241 RNLQDLARIYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRINTYVFVGNQLIPQPL 300
           RNLQDLARIYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRINTYVFVGNQLIPQPL
Sbjct: 241 RNLQDLARIYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRINTYVFVGNQLIPQPL 300

Query: 301 DSEEDEKMEEDNKEEEEKDHNEAMKPEEPPQNLLREKIMKLPLPESLKAYLTYFRDK 357
           DSEEDEKMEEDNKEEEEKDHNEAMKPEEPPQNLLREKIMKLPLPESLKAYLTYFRDK
Sbjct: 301 DSEEDEKMEEDNKEEEEKDHNEAMKPEEPPQNLLREKIMKLPLPESLKAYLTYFRDK 357


>gi|157388995 protein-L-isoaspartate (D-aspartate)
           O-methyltransferase domain containing 2 isoform 1 [Homo
           sapiens]
          Length = 361

 Score =  488 bits (1257), Expect = e-138
 Identities = 245/363 (67%), Positives = 296/363 (81%), Gaps = 8/363 (2%)

Query: 1   MGGAVSAGEDNDDLIDNLKEAQYIRTERVEQAFRAIDRGDYYLEGYRDNAYKDLAWKHGN 60
           MGGAVSAGEDND+LIDNLKEAQYIRTE VEQAFRAIDR DYYLE +++NAYKDLAWKHGN
Sbjct: 1   MGGAVSAGEDNDELIDNLKEAQYIRTELVEQAFRAIDRADYYLEEFKENAYKDLAWKHGN 60

Query: 61  IHLSAPCIYSEVMEALKLQPGLSFLNLGSGTGYLSTMVGLILGPFGINHGIELHSDVVEY 120
           IHLSAPCIYSEVMEAL LQPGLSFLNLGSGTGYLS+MVGLILGPFG+NHG+ELHSDV+EY
Sbjct: 61  IHLSAPCIYSEVMEALDLQPGLSFLNLGSGTGYLSSMVGLILGPFGVNHGVELHSDVIEY 120

Query: 121 AKEKLESFIKNSDSFDKFEFCEPAFVVGNCLQIASDSHQYDRIYCGAGVQKDHENYMKIL 180
           AK+KL+ FI+ SDSFDKF+FCEP+FV GNCL+I+ D  QYDR+YCGAGVQK+HE YMK L
Sbjct: 121 AKQKLDFFIRTSDSFDKFDFCEPSFVTGNCLEISPDCSQYDRVYCGAGVQKEHEEYMKNL 180

Query: 181 LKVGGILVMPIEDQLTQIMRTGQNTWESKNILAVSFAPLVQPSKNDNGKPDSVGLPPCAV 240
           LKVGGILVMP+E++LT+I RTG + WE+K ILAVSFAPL+QP  +++GK   V LPP AV
Sbjct: 181 LKVGGILVMPLEEKLTKITRTGPSAWETKKILAVSFAPLIQPCHSESGKSRLVQLPPVAV 240

Query: 241 RNLQDLARIYIRRTLRNFINDEMQAK-GIPQRAPPKRKRKRV-KQRINTYVFVGNQL--- 295
           R+LQDLARI IR T++  I+ E  +K G   +  P+ KR+RV ++R+ T VF+  ++   
Sbjct: 241 RSLQDLARIAIRGTIKKIIHQETVSKNGNGLKNTPRFKRRRVRRRRMETIVFLDKEVFAS 300

Query: 296 -IPQPLDSEEDEKMEEDNKEEEEKDHNEAMKPEEPPQNLLREKIMKLPLPESLKAYLTYF 354
            I  P D    E +EE+ +EEEEK   E  KP +PP N LR+K++ LPLP+ LK YL Y+
Sbjct: 301 RISNPSDDNSCEDLEEERREEEEKTPPET-KP-DPPVNFLRQKVLSLPLPDPLKYYLLYY 358

Query: 355 RDK 357
           R+K
Sbjct: 359 REK 361


>gi|157388997 protein-L-isoaspartate (D-aspartate)
           O-methyltransferase domain containing 2 isoform 2 [Homo
           sapiens]
          Length = 334

 Score =  435 bits (1119), Expect = e-122
 Identities = 226/363 (62%), Positives = 273/363 (75%), Gaps = 35/363 (9%)

Query: 1   MGGAVSAGEDNDDLIDNLKEAQYIRTERVEQAFRAIDRGDYYLEGYRDNAYKDLAWKHGN 60
           MGGAVSAGEDND+LIDNLKEAQYIRTE VEQAFRAIDR DYYLE +++NAYKDLAWKHGN
Sbjct: 1   MGGAVSAGEDNDELIDNLKEAQYIRTELVEQAFRAIDRADYYLEEFKENAYKDLAWKHGN 60

Query: 61  IHLSAPCIYSEVMEALKLQPGLSFLNLGSGTGYLSTMVGLILGPFGINHGIELHSDVVEY 120
           IHLSAPCIYSEVMEAL LQPGLSFLNLGSGTGYLS+MVGLILGPFG+NHG+ELHSDV+EY
Sbjct: 61  IHLSAPCIYSEVMEALDLQPGLSFLNLGSGTGYLSSMVGLILGPFGVNHGVELHSDVIEY 120

Query: 121 AKEKLESFIKNSDSFDKFEFCEPAFVVGNCLQIASDSHQYDRIYCGAGVQKDHENYMKIL 180
           AK+KL+ FI+ SDSFDKF+FCEP+FV GNCL+I+ D  QYDR+YCGAGVQK+HE YMK L
Sbjct: 121 AKQKLDFFIRTSDSFDKFDFCEPSFVTGNCLEISPDCSQYDRVYCGAGVQKEHEEYMKNL 180

Query: 181 LKVGGILVMPIEDQLTQIMRTGQNTWESKNILAVSFAPLVQPSKNDNGKPDSVGLPPCAV 240
           LKVGGILVMP+E+                           +P  +++GK   V LPP AV
Sbjct: 181 LKVGGILVMPLEE---------------------------KPCHSESGKSRLVQLPPVAV 213

Query: 241 RNLQDLARIYIRRTLRNFINDEMQAK-GIPQRAPPKRKRKRV-KQRINTYVFVGNQL--- 295
           R+LQDLARI IR T++  I+ E  +K G   +  P+ KR+RV ++R+ T VF+  ++   
Sbjct: 214 RSLQDLARIAIRGTIKKIIHQETVSKNGNGLKNTPRFKRRRVRRRRMETIVFLDKEVFAS 273

Query: 296 -IPQPLDSEEDEKMEEDNKEEEEKDHNEAMKPEEPPQNLLREKIMKLPLPESLKAYLTYF 354
            I  P D    E +EE+ +EEEEK   E  KP +PP N LR+K++ LPLP+ LK YL Y+
Sbjct: 274 RISNPSDDNSCEDLEEERREEEEKTPPET-KP-DPPVNFLRQKVLSLPLPDPLKYYLLYY 331

Query: 355 RDK 357
           R+K
Sbjct: 332 REK 334


>gi|239757983 PREDICTED: similar to protein-L-isoaspartate
           (D-aspartate) O-methyltransferase domain containing 1
           [Homo sapiens]
          Length = 132

 Score =  238 bits (607), Expect = 6e-63
 Identities = 116/128 (90%), Positives = 121/128 (94%)

Query: 230 PDSVGLPPCAVRNLQDLARIYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRINTYV 289
           P ++G+PP AVRNLQDLA IYIRRTLR F NDEMQAKGIPQRAPPKRKRKR KQRI TYV
Sbjct: 5   PRALGIPPSAVRNLQDLALIYIRRTLRKFTNDEMQAKGIPQRAPPKRKRKRAKQRITTYV 64

Query: 290 FVGNQLIPQPLDSEEDEKMEEDNKEEEEKDHNEAMKPEEPPQNLLREKIMKLPLPESLKA 349
           FVGNQLIPQPLDSEEDE+MEEDNKEEEEKDH+EAMKPEEPPQNLLREKIMKLPLPESLKA
Sbjct: 65  FVGNQLIPQPLDSEEDEEMEEDNKEEEEKDHSEAMKPEEPPQNLLREKIMKLPLPESLKA 124

Query: 350 YLTYFRDK 357
           YLTYFRDK
Sbjct: 125 YLTYFRDK 132


>gi|239747889 PREDICTED: hypothetical protein XP_002346467 [Homo
           sapiens]
          Length = 132

 Score =  238 bits (607), Expect = 6e-63
 Identities = 116/128 (90%), Positives = 121/128 (94%)

Query: 230 PDSVGLPPCAVRNLQDLARIYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRINTYV 289
           P ++G+PP AVRNLQDLA IYIRRTLR F NDEMQAKGIPQRAPPKRKRKR KQRI TYV
Sbjct: 5   PRALGIPPSAVRNLQDLALIYIRRTLRKFTNDEMQAKGIPQRAPPKRKRKRAKQRITTYV 64

Query: 290 FVGNQLIPQPLDSEEDEKMEEDNKEEEEKDHNEAMKPEEPPQNLLREKIMKLPLPESLKA 349
           FVGNQLIPQPLDSEEDE+MEEDNKEEEEKDH+EAMKPEEPPQNLLREKIMKLPLPESLKA
Sbjct: 65  FVGNQLIPQPLDSEEDEEMEEDNKEEEEKDHSEAMKPEEPPQNLLREKIMKLPLPESLKA 124

Query: 350 YLTYFRDK 357
           YLTYFRDK
Sbjct: 125 YLTYFRDK 132


>gi|239752574 PREDICTED: hypothetical protein XP_002348296 [Homo
           sapiens]
          Length = 164

 Score =  229 bits (583), Expect = 4e-60
 Identities = 119/152 (78%), Positives = 124/152 (81%), Gaps = 14/152 (9%)

Query: 220 VQPSKNDNGKPDSVGLPPC--------------AVRNLQDLARIYIRRTLRNFINDEMQA 265
           + P  N +  P ++G PP                VRNLQDLARIYIR TLRNFINDEMQA
Sbjct: 13  LHPFMNMHEHPRALGNPPSEGPRNHRHRALCGVTVRNLQDLARIYIRCTLRNFINDEMQA 72

Query: 266 KGIPQRAPPKRKRKRVKQRINTYVFVGNQLIPQPLDSEEDEKMEEDNKEEEEKDHNEAMK 325
           KGIPQRAPPKRKRKRVKQRI TYVFVGNQLIPQPLDSEEDEKMEEDNKEEEEKDH+EAMK
Sbjct: 73  KGIPQRAPPKRKRKRVKQRITTYVFVGNQLIPQPLDSEEDEKMEEDNKEEEEKDHSEAMK 132

Query: 326 PEEPPQNLLREKIMKLPLPESLKAYLTYFRDK 357
           PEEPPQNLL EKIMKL LPESLKAYLTYFRDK
Sbjct: 133 PEEPPQNLLTEKIMKLTLPESLKAYLTYFRDK 164


>gi|239758102 PREDICTED: similar to protein-L-isoaspartate
           (D-aspartate) O-methyltransferase domain containing 1
           [Homo sapiens]
          Length = 118

 Score =  227 bits (578), Expect = 1e-59
 Identities = 112/116 (96%), Positives = 113/116 (97%)

Query: 242 NLQDLARIYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRINTYVFVGNQLIPQPLD 301
           NLQDLARIYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRI TYVFVGNQLIPQPLD
Sbjct: 3   NLQDLARIYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRITTYVFVGNQLIPQPLD 62

Query: 302 SEEDEKMEEDNKEEEEKDHNEAMKPEEPPQNLLREKIMKLPLPESLKAYLTYFRDK 357
           SEEDEKMEEDNKEEEEKDH+EAMKPEEPPQNLL EKIMKL LPESLKAYLTYFRDK
Sbjct: 63  SEEDEKMEEDNKEEEEKDHSEAMKPEEPPQNLLTEKIMKLTLPESLKAYLTYFRDK 118


>gi|239756570 PREDICTED: similar to protein-L-isoaspartate
           (D-aspartate) O-methyltransferase domain containing 1
           [Homo sapiens]
          Length = 150

 Score =  214 bits (545), Expect = 1e-55
 Identities = 110/127 (86%), Positives = 113/127 (88%)

Query: 231 DSVGLPPCAVRNLQDLARIYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRINTYVF 290
           DS+      VRNLQDLA IYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRI  YV 
Sbjct: 24  DSLTHAGITVRNLQDLALIYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRITIYVC 83

Query: 291 VGNQLIPQPLDSEEDEKMEEDNKEEEEKDHNEAMKPEEPPQNLLREKIMKLPLPESLKAY 350
           V NQLI QPLDSEEDE+MEEDNKEEEEKDH+EAMKPEEPPQ LL EKIMKLPLPESLKAY
Sbjct: 84  VCNQLILQPLDSEEDEEMEEDNKEEEEKDHSEAMKPEEPPQYLLTEKIMKLPLPESLKAY 143

Query: 351 LTYFRDK 357
           LTYFRDK
Sbjct: 144 LTYFRDK 150


>gi|239752577 PREDICTED: hypothetical protein XP_002348294 [Homo
           sapiens]
          Length = 150

 Score =  214 bits (545), Expect = 1e-55
 Identities = 110/127 (86%), Positives = 113/127 (88%)

Query: 231 DSVGLPPCAVRNLQDLARIYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRINTYVF 290
           DS+      VRNLQDLA IYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRI  YV 
Sbjct: 24  DSLTHAGITVRNLQDLALIYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRITIYVC 83

Query: 291 VGNQLIPQPLDSEEDEKMEEDNKEEEEKDHNEAMKPEEPPQNLLREKIMKLPLPESLKAY 350
           V NQLI QPLDSEEDE+MEEDNKEEEEKDH+EAMKPEEPPQ LL EKIMKLPLPESLKAY
Sbjct: 84  VCNQLILQPLDSEEDEEMEEDNKEEEEKDHSEAMKPEEPPQYLLTEKIMKLPLPESLKAY 143

Query: 351 LTYFRDK 357
           LTYFRDK
Sbjct: 144 LTYFRDK 150


>gi|239745549 PREDICTED: hypothetical protein XP_002343514 [Homo
           sapiens]
          Length = 150

 Score =  214 bits (545), Expect = 1e-55
 Identities = 110/127 (86%), Positives = 113/127 (88%)

Query: 231 DSVGLPPCAVRNLQDLARIYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRINTYVF 290
           DS+      VRNLQDLA IYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRI  YV 
Sbjct: 24  DSLTHAGITVRNLQDLALIYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRITIYVC 83

Query: 291 VGNQLIPQPLDSEEDEKMEEDNKEEEEKDHNEAMKPEEPPQNLLREKIMKLPLPESLKAY 350
           V NQLI QPLDSEEDE+MEEDNKEEEEKDH+EAMKPEEPPQ LL EKIMKLPLPESLKAY
Sbjct: 84  VCNQLILQPLDSEEDEEMEEDNKEEEEKDHSEAMKPEEPPQYLLTEKIMKLPLPESLKAY 143

Query: 351 LTYFRDK 357
           LTYFRDK
Sbjct: 144 LTYFRDK 150


>gi|226530908 protein-L-isoaspartate (D-aspartate)
           O-methyltransferase 1 [Homo sapiens]
          Length = 285

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 61/231 (26%), Positives = 101/231 (43%), Gaps = 26/231 (11%)

Query: 6   SAGEDNDDLIDNLKEAQYIRTERVEQAFRAIDRGDYYLEGYRDNAYKDLAWKHG-NIHLS 64
           S G  + +LI NL++   I+T++V +   A DR  Y     + N Y D     G    +S
Sbjct: 63  SGGASHSELIHNLRKNGIIKTDKVFEVMLATDRSHY----AKCNPYMDSPQSIGFQATIS 118

Query: 65  APCIYSEVMEAL--KLQPGLSFLNLGSGTGYLST----MVGLILGPFGINHGIELHSDVV 118
           AP +++  +E L  +L  G   L++GSG+G L+     MVG      GI+H  EL  D V
Sbjct: 119 APHMHAYALELLFDQLHEGAKALDVGSGSGILTACFARMVGCTGKVIGIDHIKELVDDSV 178

Query: 119 EYAKEKLESFIKNSDSFDKFEFCEPAFVVGNCLQIASDSHQYDRIYCGAGVQKDHENYMK 178
              ++   + + +              VVG+     ++   YD I+ GA      +  + 
Sbjct: 179 NNVRKDDPTLLSSG---------RVQLVVGDGRMGYAEEAPYDAIHVGAAAPVVPQALID 229

Query: 179 ILLKVGGILVMPI-----EDQLTQIMRTGQNTWESKNILAVSFAPLVQPSK 224
             LK GG L++P+        L Q  +    + + K ++ V + PL    K
Sbjct: 230 -QLKPGGRLILPVGPAGGNQMLEQYDKLQDGSIKMKPLMGVIYVPLTDKEK 279


>gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo
            sapiens]
          Length = 5033

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 23/61 (37%), Positives = 36/61 (59%), Gaps = 6/61 (9%)

Query: 301  DSEEDEKMEEDNKEEEEKDHNEAMKPEEPPQNLLREKIMKLPLPESLKA----YLTYFRD 356
            + EEDE+     KE+EEK+  EA + E+  +  L E ++++ LPES+K      L YF D
Sbjct: 1891 EKEEDEEETAQEKEDEEKEEEEAAEGEK--EEGLEEGLLQMKLPESVKLQMCHLLEYFCD 1948

Query: 357  K 357
            +
Sbjct: 1949 Q 1949


>gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo
            sapiens]
          Length = 5038

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 23/61 (37%), Positives = 36/61 (59%), Gaps = 6/61 (9%)

Query: 301  DSEEDEKMEEDNKEEEEKDHNEAMKPEEPPQNLLREKIMKLPLPESLKA----YLTYFRD 356
            + EEDE+     KE+EEK+  EA + E+  +  L E ++++ LPES+K      L YF D
Sbjct: 1891 EKEEDEEETAQEKEDEEKEEEEAAEGEK--EEGLEEGLLQMKLPESVKLQMCHLLEYFCD 1948

Query: 357  K 357
            +
Sbjct: 1949 Q 1949


>gi|115511012 coiled-coil domain containing 136 [Homo sapiens]
          Length = 1154

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 32/135 (23%), Positives = 62/135 (45%), Gaps = 8/135 (5%)

Query: 223  SKNDNGKPDSVGLPPCAVRNLQDLARIYIRRTLRNFINDEMQAKGIPQRAPPKRKRKRVK 282
            +KN NG        PC+  +  DL        +  +   + +  G+ +    K + +  K
Sbjct: 988  NKNANGVKMKKVTKPCSDTSESDLETRKSLEVVLYYKASQRKLDGLAKEEEKKEEMEEEK 1047

Query: 283  QRINTYVF--VGNQLIPQPLDSE-----EDEKMEEDNKEEEEKDHNEAMKPEEPPQNL-L 334
            +++        G++L+ +P D E     ED++  E++KEEEEK+ +   + ++   +L  
Sbjct: 1048 KQVKEEAKEQCGDELVAEPADPEEAKSTEDQEENEEDKEEEEKEEDSEEEEDDADSSLES 1107

Query: 335  REKIMKLPLPESLKA 349
             E+   L L ES K+
Sbjct: 1108 PEENNPLRLSESKKS 1122


>gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens]
          Length = 224

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 17/47 (36%), Positives = 29/47 (61%)

Query: 299 PLDSEEDEKMEEDNKEEEEKDHNEAMKPEEPPQNLLREKIMKLPLPE 345
           P D EEDE+ EE+ +EEEE++  E  +   PP  ++ E+ ++   P+
Sbjct: 41  PDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAPD 87


>gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo
           sapiens]
          Length = 528

 Score = 36.6 bits (83), Expect = 0.035
 Identities = 18/42 (42%), Positives = 25/42 (59%)

Query: 301 DSEEDEKMEEDNKEEEEKDHNEAMKPEEPPQNLLREKIMKLP 342
           + EE+E+ EE  +EEEE+D  EA  P  PPQ     +  K+P
Sbjct: 316 EEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMP 357


>gi|118600967 shroom family member 4 [Homo sapiens]
          Length = 1493

 Score = 35.4 bits (80), Expect = 0.079
 Identities = 24/65 (36%), Positives = 32/65 (49%), Gaps = 5/65 (7%)

Query: 269  PQRAPPKRKRKRVKQRINTYVFVGNQLIPQPLDSEEDEKMEEDNKEEEEKDHNEAMKPEE 328
            P R PP    K    R+        Q   Q    EE+E+ EE+ +EEEE++  EA + EE
Sbjct: 1101 PPRPPPPNWEK---YRLFRAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEE 1157

Query: 329  --PPQ 331
              PPQ
Sbjct: 1158 ELPPQ 1162



 Score = 28.9 bits (63), Expect = 7.4
 Identities = 17/65 (26%), Positives = 31/65 (47%), Gaps = 7/65 (10%)

Query: 269  PQRAPPKRKRKRVKQRINTYVFVGNQLIPQPLDSEEDEKMEEDNKEEEEKDHNEAMKPEE 328
            P+  PP  ++ R+ +          Q   Q    ++ E+ EE+ +EEEE++  E  + EE
Sbjct: 1102 PRPPPPNWEKYRLFR-------AAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEE 1154

Query: 329  PPQNL 333
              + L
Sbjct: 1155 EEEEL 1159


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 35.4 bits (80), Expect = 0.079
 Identities = 16/47 (34%), Positives = 28/47 (59%)

Query: 301  DSEEDEKMEEDNKEEEEKDHNEAMKPEEPPQNLLREKIMKLPLPESL 347
            + EEDE+ EE+ +EEEE +  E  + EE  +  ++    +L  P+S+
Sbjct: 1073 EEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSV 1119



 Score = 32.7 bits (73), Expect = 0.51
 Identities = 15/35 (42%), Positives = 23/35 (65%)

Query: 294  QLIPQPLDSEEDEKMEEDNKEEEEKDHNEAMKPEE 328
            QL+    +S E+E+ EED +EEEE++  E  + EE
Sbjct: 1060 QLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEE 1094



 Score = 30.8 bits (68), Expect = 1.9
 Identities = 13/35 (37%), Positives = 24/35 (68%)

Query: 294  QLIPQPLDSEEDEKMEEDNKEEEEKDHNEAMKPEE 328
            +L  +  + EE+E+ EE+ +EEEE++ +E  + EE
Sbjct: 1063 ELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEE 1097



 Score = 30.4 bits (67), Expect = 2.5
 Identities = 12/28 (42%), Positives = 20/28 (71%)

Query: 301  DSEEDEKMEEDNKEEEEKDHNEAMKPEE 328
            + EE+++ EE+ +EEEE+D  E  + EE
Sbjct: 1072 EEEEEDEEEEEEEEEEEEDEEEEEEEEE 1099



 Score = 30.0 bits (66), Expect = 3.3
 Identities = 15/47 (31%), Positives = 27/47 (57%)

Query: 302  SEEDEKMEEDNKEEEEKDHNEAMKPEEPPQNLLREKIMKLPLPESLK 348
            SEE+E+ E++ +EEEE++  E  + EE  +    E+ ++   P   K
Sbjct: 1069 SEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTK 1115



 Score = 29.3 bits (64), Expect = 5.7
 Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 2/42 (4%)

Query: 301  DSEEDEKMEEDNKEEEEKDHNEAMKPEEPPQNLLREKIMKLP 342
            + EE+E  EE+ +EEEE++  E  + EE  +    E I   P
Sbjct: 1071 EEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEE--EENIQSSP 1110



 Score = 29.3 bits (64), Expect = 5.7
 Identities = 15/48 (31%), Positives = 26/48 (54%)

Query: 301  DSEEDEKMEEDNKEEEEKDHNEAMKPEEPPQNLLREKIMKLPLPESLK 348
            + EE+E+ EE+ +EEEE++  E ++   P     +   +K   P  LK
Sbjct: 1083 EEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLK 1130


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 35.0 bits (79), Expect = 0.10
 Identities = 14/28 (50%), Positives = 22/28 (78%)

Query: 301 DSEEDEKMEEDNKEEEEKDHNEAMKPEE 328
           D+EEDE+++ED +EEEE++  E  + EE
Sbjct: 218 DAEEDEEVDEDGEEEEEEEEEEEEEEEE 245



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 14/28 (50%), Positives = 20/28 (71%)

Query: 301 DSEEDEKMEEDNKEEEEKDHNEAMKPEE 328
           D EEDE++EED +E+EE D +   + EE
Sbjct: 208 DVEEDEEVEEDAEEDEEVDEDGEEEEEE 235



 Score = 30.0 bits (66), Expect = 3.3
 Identities = 14/32 (43%), Positives = 20/32 (62%)

Query: 301 DSEEDEKMEEDNKEEEEKDHNEAMKPEEPPQN 332
           D E DE  EE+ +EEEE++  E  + EE  Q+
Sbjct: 222 DEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQD 253



 Score = 29.3 bits (64), Expect = 5.7
 Identities = 12/27 (44%), Positives = 19/27 (70%)

Query: 301 DSEEDEKMEEDNKEEEEKDHNEAMKPE 327
           D EE+E+ EE+ +EEEE++  E  + E
Sbjct: 228 DGEEEEEEEEEEEEEEEEEEEEYEQDE 254



 Score = 28.9 bits (63), Expect = 7.4
 Identities = 12/28 (42%), Positives = 20/28 (71%)

Query: 301 DSEEDEKMEEDNKEEEEKDHNEAMKPEE 328
           + EE+E+ EE+ +EEEE + +E  + EE
Sbjct: 233 EEEEEEEEEEEEEEEEEYEQDERDQKEE 260


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 35.0 bits (79), Expect = 0.10
 Identities = 14/28 (50%), Positives = 22/28 (78%)

Query: 301 DSEEDEKMEEDNKEEEEKDHNEAMKPEE 328
           D+EEDE+++ED +EEEE++  E  + EE
Sbjct: 218 DAEEDEEVDEDGEEEEEEEEEEEEEEEE 245



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 14/28 (50%), Positives = 20/28 (71%)

Query: 301 DSEEDEKMEEDNKEEEEKDHNEAMKPEE 328
           D EEDE++EED +E+EE D +   + EE
Sbjct: 208 DVEEDEEVEEDAEEDEEVDEDGEEEEEE 235



 Score = 30.0 bits (66), Expect = 3.3
 Identities = 14/32 (43%), Positives = 20/32 (62%)

Query: 301 DSEEDEKMEEDNKEEEEKDHNEAMKPEEPPQN 332
           D E DE  EE+ +EEEE++  E  + EE  Q+
Sbjct: 222 DEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQD 253



 Score = 29.3 bits (64), Expect = 5.7
 Identities = 12/27 (44%), Positives = 19/27 (70%)

Query: 301 DSEEDEKMEEDNKEEEEKDHNEAMKPE 327
           D EE+E+ EE+ +EEEE++  E  + E
Sbjct: 228 DGEEEEEEEEEEEEEEEEEEEEYEQDE 254



 Score = 28.9 bits (63), Expect = 7.4
 Identities = 12/28 (42%), Positives = 20/28 (71%)

Query: 301 DSEEDEKMEEDNKEEEEKDHNEAMKPEE 328
           + EE+E+ EE+ +EEEE + +E  + EE
Sbjct: 233 EEEEEEEEEEEEEEEEEYEQDERDQKEE 260


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 34.7 bits (78), Expect = 0.13
 Identities = 21/74 (28%), Positives = 39/74 (52%), Gaps = 5/74 (6%)

Query: 275  KRKRKRVKQRINTYVFVGNQLIPQPLDSEEDEKMEEDNKEEEEKDHNEAMKPEEPPQNLL 334
            K+KR+R+K + ++     +       + EE+EK EE+ +EEEE++  E    +       
Sbjct: 1384 KKKRRRIKVQEDS-----SSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKG 1438

Query: 335  REKIMKLPLPESLK 348
            R+KI K+   + L+
Sbjct: 1439 RKKIRKILKDDKLR 1452



 Score = 30.0 bits (66), Expect = 3.3
 Identities = 20/67 (29%), Positives = 38/67 (56%), Gaps = 2/67 (2%)

Query: 275  KRKRKRVKQRINTYVFVGNQLIPQPLDSEEDEKMEEDNKE-EEEKDHNEAMKPEEPPQNL 333
            K+K+KR + ++       N+   +  + E++E+ EE+ +E EEE+D N+  K     +  
Sbjct: 1382 KQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKK 1441

Query: 334  LREKIMK 340
            +R KI+K
Sbjct: 1442 IR-KILK 1447


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 34.7 bits (78), Expect = 0.13
 Identities = 21/74 (28%), Positives = 39/74 (52%), Gaps = 5/74 (6%)

Query: 275  KRKRKRVKQRINTYVFVGNQLIPQPLDSEEDEKMEEDNKEEEEKDHNEAMKPEEPPQNLL 334
            K+KR+R+K + ++     +       + EE+EK EE+ +EEEE++  E    +       
Sbjct: 1422 KKKRRRIKVQEDS-----SSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKG 1476

Query: 335  REKIMKLPLPESLK 348
            R+KI K+   + L+
Sbjct: 1477 RKKIRKILKDDKLR 1490



 Score = 30.0 bits (66), Expect = 3.3
 Identities = 20/67 (29%), Positives = 38/67 (56%), Gaps = 2/67 (2%)

Query: 275  KRKRKRVKQRINTYVFVGNQLIPQPLDSEEDEKMEEDNKE-EEEKDHNEAMKPEEPPQNL 333
            K+K+KR + ++       N+   +  + E++E+ EE+ +E EEE+D N+  K     +  
Sbjct: 1420 KQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKK 1479

Query: 334  LREKIMK 340
            +R KI+K
Sbjct: 1480 IR-KILK 1485


>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
           exchanger), member 1 [Homo sapiens]
          Length = 1099

 Score = 34.7 bits (78), Expect = 0.13
 Identities = 19/54 (35%), Positives = 31/54 (57%), Gaps = 1/54 (1%)

Query: 301 DSEEDEKMEEDNKEEEEKDHNEAMKPEEPPQNLL-REKIMKLPLPESLKAYLTY 353
           DSEE+E+ EE+ +EEEE++  E  + EE  +     E+ + L  PE+ +    Y
Sbjct: 858 DSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDWPETRQKQAIY 911



 Score = 30.4 bits (67), Expect = 2.5
 Identities = 16/52 (30%), Positives = 28/52 (53%)

Query: 301 DSEEDEKMEEDNKEEEEKDHNEAMKPEEPPQNLLREKIMKLPLPESLKAYLT 352
           + EE+++ EE+ +EEEE+  NE     + P+   ++ I    LP     +LT
Sbjct: 873 EEEEEQEEEEEEEEEEEEKGNEEPLSLDWPETRQKQAIYLFLLPIVFPLWLT 924



 Score = 29.3 bits (64), Expect = 5.7
 Identities = 14/43 (32%), Positives = 24/43 (55%)

Query: 301 DSEEDEKMEEDNKEEEEKDHNEAMKPEEPPQNLLREKIMKLPL 343
           D  + E+ EE+ +E+EE++  E  + EE  +    EK  + PL
Sbjct: 855 DGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPL 897


>gi|5454156 ubiquitin specific protease 16 isoform a [Homo sapiens]
          Length = 823

 Score = 33.5 bits (75), Expect = 0.30
 Identities = 14/42 (33%), Positives = 26/42 (61%), Gaps = 6/42 (14%)

Query: 297 PQPLDSE------EDEKMEEDNKEEEEKDHNEAMKPEEPPQN 332
           P+P + +      E++K+E+++K E+E++  E M  E PP N
Sbjct: 147 PKPAEKDNGNIELENKKLEKESKNEQEREKKENMAKENPPMN 188


>gi|75992941 ubiquitin specific protease 16 isoform a [Homo sapiens]
          Length = 823

 Score = 33.5 bits (75), Expect = 0.30
 Identities = 14/42 (33%), Positives = 26/42 (61%), Gaps = 6/42 (14%)

Query: 297 PQPLDSE------EDEKMEEDNKEEEEKDHNEAMKPEEPPQN 332
           P+P + +      E++K+E+++K E+E++  E M  E PP N
Sbjct: 147 PKPAEKDNGNIELENKKLEKESKNEQEREKKENMAKENPPMN 188


>gi|38788333 remodeling and spacing factor 1 [Homo sapiens]
          Length = 1441

 Score = 33.5 bits (75), Expect = 0.30
 Identities = 17/34 (50%), Positives = 24/34 (70%), Gaps = 1/34 (2%)

Query: 300 LDSEEDEKMEEDNKEEEEKDHNEAMKPEEPPQNL 333
           L+ EE +K EE  K+EE+K+ +E MK EE P +L
Sbjct: 230 LEDEETKKEEETPKQEEQKE-SEKMKSEEQPMDL 262



 Score = 30.4 bits (67), Expect = 2.5
 Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 12/84 (14%)

Query: 253  RTLRNFINDEMQAKGIPQRAPPKRKRKRVKQRINTYVFVGNQLIPQPLDSEEDE---KME 309
            + +   +++E +    PQRA   R++KR  +R+N      N      LD EE E   K+ 
Sbjct: 1061 KDISTILDEERKENKRPQRAAAARRKKR--RRLNDLDSDSN------LDEEESEDEFKIS 1112

Query: 310  EDNKEE-EEKDHNEAMKPEEPPQN 332
            + +++E    D N     E+PP N
Sbjct: 1113 DGSQDEFVVSDENPDESEEDPPSN 1136


>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 123

 Score = 33.5 bits (75), Expect = 0.30
 Identities = 19/54 (35%), Positives = 29/54 (53%), Gaps = 13/54 (24%)

Query: 275 KRKRKRVKQRINTYVFVGNQLIPQPLDSEEDEKMEEDNKEEEEKDHNEAMKPEE 328
           KRKRKR K++             +  + EE+E+ EE+ KEEEEK+     K ++
Sbjct: 61  KRKRKRKKKK-------------EEEEREEEEEEEEEEKEEEEKEEGRRRKKKK 101



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 22/75 (29%), Positives = 35/75 (46%), Gaps = 9/75 (12%)

Query: 275 KRKRKRVKQRINTYVFVGNQLIPQPLDSEEDEKM---------EEDNKEEEEKDHNEAMK 325
           KRK KR ++R         +   +  + EE+EK          EE+ +EEEE++  E  +
Sbjct: 28  KRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKE 87

Query: 326 PEEPPQNLLREKIMK 340
            EE  +   R+K  K
Sbjct: 88  EEEKEEGRRRKKKKK 102


>gi|56676330 HP1-BP74 [Homo sapiens]
          Length = 553

 Score = 33.5 bits (75), Expect = 0.30
 Identities = 18/63 (28%), Positives = 32/63 (50%)

Query: 282 KQRINTYVFVGNQLIPQPLDSEEDEKMEEDNKEEEEKDHNEAMKPEEPPQNLLREKIMKL 341
           ++ ++T     N+  P      E  K E +N+E+EE   +E  K +E  Q+  +EK +K 
Sbjct: 72  EESVSTVEEQENETPPATSSEAEQPKGEPENEEKEENKSSEETKKDEKDQSKEKEKKVKK 131

Query: 342 PLP 344
            +P
Sbjct: 132 TIP 134


>gi|62241003 cardiomyopathy associated 5 [Homo sapiens]
          Length = 4069

 Score = 33.5 bits (75), Expect = 0.30
 Identities = 21/54 (38%), Positives = 28/54 (51%), Gaps = 1/54 (1%)

Query: 293 NQLIPQPLDSEEDEKMEEDNKEEEEKDHNEAMKPEEPPQNLLREKIMKLPLPES 346
           N L P  +   E   +EE  KEE E     A+ PE    NL+ E+I++L  PES
Sbjct: 487 NMLEPS-ISLSEPLMLEEPEKEEIETSLPIAITPEPEDSNLVEEEIVELDYPES 539


>gi|50312664 ubiquitin specific protease 16 isoform b [Homo sapiens]
          Length = 822

 Score = 33.1 bits (74), Expect = 0.39
 Identities = 12/29 (41%), Positives = 21/29 (72%)

Query: 304 EDEKMEEDNKEEEEKDHNEAMKPEEPPQN 332
           E++K+E+++K E+E++  E M  E PP N
Sbjct: 159 ENKKLEKESKNEQEREKKENMAKENPPMN 187


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.136    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,719,486
Number of Sequences: 37866
Number of extensions: 719128
Number of successful extensions: 9126
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 168
Number of HSP's successfully gapped in prelim test: 85
Number of HSP's that attempted gapping in prelim test: 6657
Number of HSP's gapped (non-prelim): 1587
length of query: 357
length of database: 18,247,518
effective HSP length: 103
effective length of query: 254
effective length of database: 14,347,320
effective search space: 3644219280
effective search space used: 3644219280
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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