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Search of human proteins with 190014636
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|190014636 hypothetical protein LOC286262 isoform 2 [Homo
sapiens]
(678 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|190014636 hypothetical protein LOC286262 isoform 2 [Homo sapi... 1376 0.0
gi|190014638 hypothetical protein LOC286262 isoform 1 [Homo sapi... 1300 0.0
gi|163965366 nascent polypeptide-associated complex alpha subuni... 89 1e-17
gi|145386517 phostensin [Homo sapiens] 82 2e-15
gi|199559805 phostensin [Homo sapiens] 82 2e-15
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 72 2e-12
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho... 70 8e-12
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 69 1e-11
gi|110832843 TBP-associated factor 4 [Homo sapiens] 69 1e-11
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 67 4e-11
gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens] 67 4e-11
gi|47132519 Ras association and pleckstrin homology domains 1 is... 67 7e-11
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 67 7e-11
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 66 1e-10
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 65 2e-10
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 65 2e-10
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 65 3e-10
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 64 6e-10
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 64 6e-10
gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 63 8e-10
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 63 1e-09
gi|237757308 synaptojanin 1 isoform b [Homo sapiens] 62 1e-09
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 62 1e-09
gi|19924099 synapsin I isoform Ia [Homo sapiens] 62 2e-09
gi|33667117 MICAL-like 2 isoform 1 [Homo sapiens] 62 2e-09
gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens] 62 2e-09
gi|22027541 programmed cell death 7 [Homo sapiens] 62 2e-09
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 62 2e-09
gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor ... 61 3e-09
gi|19924097 synapsin I isoform Ib [Homo sapiens] 61 4e-09
>gi|190014636 hypothetical protein LOC286262 isoform 2 [Homo
sapiens]
Length = 678
Score = 1376 bits (3561), Expect = 0.0
Identities = 678/678 (100%), Positives = 678/678 (100%)
Query: 1 MLLEAERRRGGGAAGARLLERYRRVPGVRALRADSVLIIETVPGFPPAPPAPGAAQIRAA 60
MLLEAERRRGGGAAGARLLERYRRVPGVRALRADSVLIIETVPGFPPAPPAPGAAQIRAA
Sbjct: 1 MLLEAERRRGGGAAGARLLERYRRVPGVRALRADSVLIIETVPGFPPAPPAPGAAQIRAA 60
Query: 61 EVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPAPPRPPPAAPSPPAAPG 120
EVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPAPPRPPPAAPSPPAAPG
Sbjct: 61 EVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPAPPRPPPAAPSPPAAPG 120
Query: 121 PRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGS 180
PRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGS
Sbjct: 121 PRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGS 180
Query: 181 PPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATPSQRQCVSAATSTNDSFEIRP 240
PPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATPSQRQCVSAATSTNDSFEIRP
Sbjct: 181 PPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATPSQRQCVSAATSTNDSFEIRP 240
Query: 241 APKPVMETIPLGDLQARALASLRANSRNSFMVIPKSKASGAPPPEGRQSVELPKGDLGPA 300
APKPVMETIPLGDLQARALASLRANSRNSFMVIPKSKASGAPPPEGRQSVELPKGDLGPA
Sbjct: 241 APKPVMETIPLGDLQARALASLRANSRNSFMVIPKSKASGAPPPEGRQSVELPKGDLGPA 300
Query: 301 SPSQELGSQPVPGGDGAPALGKSPLEVEAQWAVEEGACPRTATALADRAIRWQRPSSPPP 360
SPSQELGSQPVPGGDGAPALGKSPLEVEAQWAVEEGACPRTATALADRAIRWQRPSSPPP
Sbjct: 301 SPSQELGSQPVPGGDGAPALGKSPLEVEAQWAVEEGACPRTATALADRAIRWQRPSSPPP 360
Query: 361 FLPAASEEAEPAEGLRVPGLAKNSREYVRPGLPVTFIDEVDSEEAPQAAKLPYLPHPARP 420
FLPAASEEAEPAEGLRVPGLAKNSREYVRPGLPVTFIDEVDSEEAPQAAKLPYLPHPARP
Sbjct: 361 FLPAASEEAEPAEGLRVPGLAKNSREYVRPGLPVTFIDEVDSEEAPQAAKLPYLPHPARP 420
Query: 421 LHPARPGCVAELQPRGSNTFTVVPKRKPGTLQDQHFSQANREPRPREAEEEEASCLLGPT 480
LHPARPGCVAELQPRGSNTFTVVPKRKPGTLQDQHFSQANREPRPREAEEEEASCLLGPT
Sbjct: 421 LHPARPGCVAELQPRGSNTFTVVPKRKPGTLQDQHFSQANREPRPREAEEEEASCLLGPT 480
Query: 481 LKKRYPTVHEIEVIGGYLALQKSCLTKAGSSRKKMKISFNDKSLQTTFEYPSESSLEQEE 540
LKKRYPTVHEIEVIGGYLALQKSCLTKAGSSRKKMKISFNDKSLQTTFEYPSESSLEQEE
Sbjct: 481 LKKRYPTVHEIEVIGGYLALQKSCLTKAGSSRKKMKISFNDKSLQTTFEYPSESSLEQEE 540
Query: 541 EVDQQEEEEEEEEEEEEEEEGSGSEEKPFALFLPRATFVSSVRPESSRLPEGSSGLSSYT 600
EVDQQEEEEEEEEEEEEEEEGSGSEEKPFALFLPRATFVSSVRPESSRLPEGSSGLSSYT
Sbjct: 541 EVDQQEEEEEEEEEEEEEEEGSGSEEKPFALFLPRATFVSSVRPESSRLPEGSSGLSSYT 600
Query: 601 PKHSVAFSKWQEQALEQAPREAEPPPVEAMVRCGGVERWGESDTRASPCVHILSSHFQLT 660
PKHSVAFSKWQEQALEQAPREAEPPPVEAMVRCGGVERWGESDTRASPCVHILSSHFQLT
Sbjct: 601 PKHSVAFSKWQEQALEQAPREAEPPPVEAMVRCGGVERWGESDTRASPCVHILSSHFQLT 660
Query: 661 PASQNDLSDFRSEPALYF 678
PASQNDLSDFRSEPALYF
Sbjct: 661 PASQNDLSDFRSEPALYF 678
>gi|190014638 hypothetical protein LOC286262 isoform 1 [Homo
sapiens]
Length = 650
Score = 1300 bits (3365), Expect = 0.0
Identities = 650/678 (95%), Positives = 650/678 (95%), Gaps = 28/678 (4%)
Query: 1 MLLEAERRRGGGAAGARLLERYRRVPGVRALRADSVLIIETVPGFPPAPPAPGAAQIRAA 60
MLLEAERRRGGGAAGARLLERYRRVPGVRALRADSVLIIETVPGFPPAPPAPGAAQIRAA
Sbjct: 1 MLLEAERRRGGGAAGARLLERYRRVPGVRALRADSVLIIETVPGFPPAPPAPGAAQIRAA 60
Query: 61 EVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPAPPRPPPAAPSPPAAPG 120
EVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPAPPRPPPAAPSPPAAPG
Sbjct: 61 EVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPAPPRPPPAAPSPPAAPG 120
Query: 121 PRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGS 180
PRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGS
Sbjct: 121 PRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGS 180
Query: 181 PPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATPSQRQCVSAATSTNDSFEIRP 240
PPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATPSQRQCVSAATSTNDSFEIRP
Sbjct: 181 PPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATPSQRQCVSAATSTNDSFEIRP 240
Query: 241 APKPVMETIPLGDLQARALASLRANSRNSFMVIPKSKASGAPPPEGRQSVELPKGDLGPA 300
APKPVMETIPLGDLQARALASLRANSRNSFMVIPKSKASGAPPPEGRQSVELPKGDLGPA
Sbjct: 241 APKPVMETIPLGDLQARALASLRANSRNSFMVIPKSKASGAPPPEGRQSVELPKGDLGPA 300
Query: 301 SPSQELGSQPVPGGDGAPALGKSPLEVEAQWAVEEGACPRTATALADRAIRWQRPSSPPP 360
SPSQELGSQPVPGGDGAPALGKSPLEVEAQWAVEEGACPRTATALADRAIRWQRPSSPPP
Sbjct: 301 SPSQELGSQPVPGGDGAPALGKSPLEVEAQWAVEEGACPRTATALADRAIRWQRPSSPPP 360
Query: 361 FLPAASEEAEPAEGLRVPGLAKNSREYVRPGLPVTFIDEVDSEEAPQAAKLPYLPHPARP 420
FLPAASEEAEPAEGLRVPGLAKNSREYVRPGLPVTFIDEVDSEEAPQAAKLPYLPHPARP
Sbjct: 361 FLPAASEEAEPAEGLRVPGLAKNSREYVRPGLPVTFIDEVDSEEAPQAAKLPYLPHPARP 420
Query: 421 LHPARPGCVAELQPRGSNTFTVVPKRKPGTLQDQHFSQANREPRPREAEEEEASCLLGPT 480
LHPARPGCVAELQPRGSNTFTVVPKRKPGTLQDQHFSQANREPRPREAEEEEASCLLGPT
Sbjct: 421 LHPARPGCVAELQPRGSNTFTVVPKRKPGTLQDQHFSQANREPRPREAEEEEASCLLGPT 480
Query: 481 LKKRYPTVHEIEVIGGYLALQKSCLTKAGSSRKKMKISFNDKSLQTTFEYPSESSLEQEE 540
LKKRYPTVHEIEVIGGYLALQKSCLTKAGSSRKKMKISFNDKSLQTTFEYPSESSLEQEE
Sbjct: 481 LKKRYPTVHEIEVIGGYLALQKSCLTKAGSSRKKMKISFNDKSLQTTFEYPSESSLEQEE 540
Query: 541 EVDQQEEEEEEEEEEEEEEEGSGSEEKPFALFLPRATFVSSVRPESSRLPEGSSGLSSYT 600
EVDQQEEEEEEEEEEEEEEEGSGSEEKPFALFLPRATFVSSVRPESSRLPEGSSGLSSYT
Sbjct: 541 EVDQQEEEEEEEEEEEEEEEGSGSEEKPFALFLPRATFVSSVRPESSRLPEGSSGLSSYT 600
Query: 601 PKHSVAFSKWQEQALEQAPREAEPPPVEAMVRCGGVERWGESDTRASPCVHILSSHFQLT 660
PKHSVAFSKWQEQALEQAPREAEPPPVEAM LT
Sbjct: 601 PKHSVAFSKWQEQALEQAPREAEPPPVEAM----------------------------LT 632
Query: 661 PASQNDLSDFRSEPALYF 678
PASQNDLSDFRSEPALYF
Sbjct: 633 PASQNDLSDFRSEPALYF 650
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 89.0 bits (219), Expect = 1e-17
Identities = 120/431 (27%), Positives = 153/431 (35%), Gaps = 73/431 (16%)
Query: 46 PPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPAP 105
PPA P AA L GAP + L PA P +G+P PP P P
Sbjct: 1035 PPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGP 1094
Query: 106 PRP-PPAAPSPPAA--PGPRGGGASPGARRSDFLQKTGSNS-----FTVHPRGLHRGAGA 157
P P AP PPAA P P+GG A+P + + S T P+G A
Sbjct: 1095 ATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA 1154
Query: 158 RLLS--NGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPP 215
S G + P P+ P A +PP PK PS P +P TP+ATP SP
Sbjct: 1155 TPPSPKGGLATPPPKGAPTTP-AATPP-----SPKGGLATPS--PKGAPTTPAATPPSPK 1206
Query: 216 AS-ATPSQRQCVSAATSTNDSFEIRPAPKPVMET-IPLGDLQARALASLRANSRNSFMVI 273
ATPS + + +T P+PK + T P G
Sbjct: 1207 GGLATPSPKGAPTTPAAT------PPSPKGGLATPSPKG--------------------A 1240
Query: 274 PKSKASGAPPPEGRQSVELPKGDLGP--ASPSQELGSQPVPGGDGAPALGKSPLEVEAQW 331
P + A+ P P+G + PKG P A+P G P GAP +P
Sbjct: 1241 PTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAP----NP------- 1289
Query: 332 AVEEGACPRTATALADRAIRWQRPSSPPPFLPAASEEAEPAEGLRVPGLAKNSREYVRPG 391
AV P+ A + P++ PP P S P +G P P
Sbjct: 1290 AVVTPPSPKGGPATSPPKGAPTPPAATPP-SPKGSPGTPPPKGAPTPPAVTPPSPKGTPT 1348
Query: 392 LPVTFIDEVDSEEAPQAAKLPYLPHPARPLHPARPGCV--------AELQPRGSNTFTVV 443
LP T P + + P P A P H P A P+G T V
Sbjct: 1349 LPATTPSSKGGPTTPSSKEGP-TPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAV 1407
Query: 444 ----PKRKPGT 450
PK+ P T
Sbjct: 1408 IPLSPKKAPAT 1418
Score = 73.6 bits (179), Expect = 6e-13
Identities = 118/431 (27%), Positives = 152/431 (35%), Gaps = 54/431 (12%)
Query: 47 PAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPE--RARPPPPPPPPA 104
PA PAP +A + + + P + PA+P +G+P A PP P PA
Sbjct: 900 PATPAPK----QAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPA 955
Query: 105 PPRP-----PPAA--PSP---PAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRG 154
P P PPAA PSP PA P P+G P A T P+G
Sbjct: 956 TPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATP----PSPKGGPATPSPKGAPTP 1011
Query: 155 AGARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPP--SPGTPSATPA 212
S S P A P + A +PP + PK G P+ P P +P TP+AT
Sbjct: 1012 PAVTPPSPKGS---PAATPFPKGASTPPAATPPSPK---GSPAATPLPKGAPTTPAATLP 1065
Query: 213 SPPAS-ATPSQRQCVSAATSTNDSFEIRPA-PKPVMETIPLGDLQARALASLRANSRNSF 270
SP ATPS + + +T S + PA P P +P L
Sbjct: 1066 SPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKG- 1124
Query: 271 MVIPKSKASGAPPPEGRQSVELPKG-----DLGPASPSQELGSQPVPGGDGAPALGKSPL 325
P + A+ P P+G + PKG P SP L + P G PA
Sbjct: 1125 --APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1182
Query: 326 EVEAQWAVEEGACPRTATALADRAIRWQRPSSPPPFLPAASEEAEPAEGLRVPGLAKNSR 385
+ +GA P T A P SP L S + P P K
Sbjct: 1183 KGGLATPSPKGA-PTTPAA---------TPPSPKGGLATPSPKGAPTTPAATPPSPKGGL 1232
Query: 386 EYVRP-GLPVTFIDEVDSEEAPQAAKLPY-LPHPARPLHPARPGCVAELQPRGSNTFTVV 443
P G P T S + A P P P P+ G +A +G+ VV
Sbjct: 1233 ATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVV 1292
Query: 444 ----PKRKPGT 450
PK P T
Sbjct: 1293 TPPSPKGGPAT 1303
Score = 66.6 bits (161), Expect = 7e-11
Identities = 84/329 (25%), Positives = 116/329 (35%), Gaps = 35/329 (10%)
Query: 72 VSRLLERFDPPAAPRRRGSPERARPPPPPPPPAP-------------PR----PPPAAPS 114
VS + F P + +GS + P PP+P P+ PP P+
Sbjct: 828 VSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPT 887
Query: 115 PPAA--PGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAG 172
P P P+ G A+P +++ L T S+ +G A G P P A
Sbjct: 888 PSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTP-PAAT 946
Query: 173 PANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATPSQRQCVSAATST 232
P + G S +W P + P P P TPS A P +ATP + A S
Sbjct: 947 PPSPKGGPATPSPKWAPTPPAATPP-SPKGGPATPSPKGAPTPPAATPPSPKGGPATPSP 1005
Query: 233 NDSFEIRPAPKPVMETIPLGDLQARALASLRANSRNSFMVIPKSKASGAPPPEG---RQS 289
+ P P V P G A + + PK + P P+G +
Sbjct: 1006 KGA----PTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPA 1061
Query: 290 VELPKGDLGPASPSQELGSQPVPGGDGAPALGKSPLEVEAQWAVEEGACPRTATALADRA 349
LP GPA+PS L P P P SP A + + P AT + +
Sbjct: 1062 ATLPSPKGGPATPS--LKGAPTPPAATPP----SPKGGPATPSPKGAPMPPAATPPSPKG 1115
Query: 350 IRWQRPSSPPPFLPAASEEAEPAEGLRVP 378
P P PAA+ + P GL P
Sbjct: 1116 GLATPPHKGAPTTPAATPPS-PKGGLATP 1143
Score = 62.0 bits (149), Expect = 2e-09
Identities = 149/668 (22%), Positives = 241/668 (36%), Gaps = 120/668 (17%)
Query: 23 RRVPGVRALRAD--SVLIIETVPGFPPAPPAP--GAAQIRAAEVLVYGAPPGRVSRLLER 78
+R P + + + D S +I P PA P GAA ++ P + +
Sbjct: 1390 KRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPAT 1449
Query: 79 FDP---PAAPRRRGSPE--RARPPPPPPPPAP--------PRPPPAAPSPPAAP------ 119
P PA P +G P PP P PPAP P+ PA P+P AP
Sbjct: 1450 SAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVI 1509
Query: 120 --GPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPR------- 170
P+ A+P +RR D + T + P L L+ + P P+
Sbjct: 1510 PSSPKEVPATPSSRR-DPIAPTATLLSKKTPATL--APKEALIPPAMTVPSPKKTPAIPT 1566
Query: 171 -----AGPANRLAGSPPG------SGQWKPK---VESGDPSLHPPPSPGTPSATPASPPA 216
A P+++ A SPP G PK + S P +P P+ TP SP
Sbjct: 1567 PKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEK 1626
Query: 217 S-ATPSQRQCVSAATSTNDSFEIRPAPKPVMETIPLGDLQARALASLRAN---------- 265
ATP+ + ++ T S + P P T +G +A L A
Sbjct: 1627 GPATPAPKGTPTSPPVTPSSLKDSPT-SPASVTCKMGATVPQASKGLPAKKGPTALKEVL 1685
Query: 266 ---SRNSFMVI-------PKSKASGA------PPPEGRQSVELPKGDLGPAS--PSQELG 307
+ S +I P++K S A P P + + P + PA P Q+
Sbjct: 1686 VAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDS 1745
Query: 308 SQPVPGGDGA--PALGKSPLEVEAQW----AVEEGACPRTATALADRA----IRWQRPSS 357
S+ G D + P +P E +A A E P+ +A A + S
Sbjct: 1746 SKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPS 1805
Query: 358 PPPFLPAASEEAEPAEGLRVPG----LAKNSREYVRPGLP-------VTFIDEVDSEEAP 406
P P LP + + GL + LA + + P +P V F + + P
Sbjct: 1806 PVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTP 1865
Query: 407 QAAKLPY-LPHPARPLHPARPGC---------VAELQPRGSNTFTVVPKRKPGT--LQDQ 454
++A +P P +P+ G V EL+ + S T + + ++
Sbjct: 1866 KSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEE 1925
Query: 455 HFSQANREPRPREAEEEEASCLLGPTLKKRYPTVHEIEVIGGYLALQKSCLTKAGSSRKK 514
S+A + ++A + + L T+ + + I + K + K+ +S
Sbjct: 1926 PVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNI--LFVITKPDVYKSPASDTY 1983
Query: 515 M---KISFNDKSLQTTFEYPSESSLEQEEEVDQQEEEEE---EEEEEEEEEEGSGSEEKP 568
+ + D S Q + ++ E + QE + +EE EEEE + +G E K
Sbjct: 1984 IVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDETGVEVKD 2043
Query: 569 FALFLPRA 576
L + +A
Sbjct: 2044 IELVMSQA 2051
Score = 32.0 bits (71), Expect = 1.9
Identities = 72/334 (21%), Positives = 117/334 (35%), Gaps = 54/334 (16%)
Query: 193 SGDPSLHPPPSPGTPSATPASPPASATPSQRQCVSAATSTNDSFEIRPAPKPVMETIPLG 252
S + + H P P ++ + P T C AA T +FE+ P M + P+
Sbjct: 418 SPNATYHYPLVAQMPVSSVGTTPLVVT---NPCTIAAAPTT-TFEVATCVSPPMSSGPIS 473
Query: 253 DLQARALASLR----ANSRNSFMVIPKSKASGAPP-PEGRQSVELPKGDLGPASPSQELG 307
+++ + A+L A S V + +PP P+ LP L ++L
Sbjct: 474 NIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQ 533
Query: 308 SQP--VPGGDGAPALGKSPLEVEAQWAVEEGACPRTATALADRAIRWQRPSSPPPFLPAA 365
+ P + G +PA + + A P+ + + + + P SP L
Sbjct: 534 TVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKK 593
Query: 366 S-----EEAEPAEGLRVPGLAKNSREYVRPGLPVTFIDEVDSEEAPQAAKLPYLPHP--- 417
S +PA + P +S ++ DS P +A P L
Sbjct: 594 SLGEPLPIGKPASSMTSPLGVNSSASVIK----------TDSYAGPDSAG-PLLKSSLIT 642
Query: 418 ----ARPLHPARPGCVAELQPRGSNTFT------------VVPKRKP---GTLQDQHFSQ 458
A PL A P VA +G++T+T + PK P GTL
Sbjct: 643 PTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVP 702
Query: 459 ANRE-----PRPREAEEEEASCLLGPTLKKRYPT 487
E P P+ A+ +L P + K P+
Sbjct: 703 TASENCPVAPSPQNTCAPLATLVLAPEIPKSVPS 736
Score = 29.6 bits (65), Expect = 9.6
Identities = 46/185 (24%), Positives = 59/185 (31%), Gaps = 23/185 (12%)
Query: 103 PAPPRPPPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSN 162
P P PPP +P+P P ASP S F G G
Sbjct: 41 PGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLG------ 94
Query: 163 GHSAPEPRAGPANRLAG--SPPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATP 220
+APE N + SP P + P+L PS P A A P S
Sbjct: 95 --TAPEAPTFLPNLIGPPISPAALALASPMIA---PTLKGTPSSSAPLALVALAPHSVQK 149
Query: 221 SQRQCVSAATSTNDSFEIRPAPKPVMETIPLGDLQARALASLRANSRNSF--MVIPKSKA 278
S + TS P V E+ + L A S + N V+P K
Sbjct: 150 SSAFPPNLLTS--------PPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKG 201
Query: 279 SGAPP 283
+ +PP
Sbjct: 202 TPSPP 206
>gi|145386517 phostensin [Homo sapiens]
Length = 613
Score = 82.0 bits (201), Expect = 2e-15
Identities = 60/164 (36%), Positives = 81/164 (49%), Gaps = 21/164 (12%)
Query: 405 APQAAKLPYLPHPARPLHPARPGCVAELQPRGSNTFTVVPKRK--PGTLQDQHFSQANRE 462
AP A + P P +R + + G R +TFTV P+R P T
Sbjct: 437 APTAPQPPGDPLMSRLFYGVKAGPGVGAPRRSGHTFTVNPRRSVPPAT------PATPTS 490
Query: 463 PRPREAEEEEASCLLGPTLKKRYPTVHEIEVIGGYLALQKSCLTKAGSSR--KKMKISFN 520
P +A A KKRYPT EI V+GGYL L +SCL K R K++KISF+
Sbjct: 491 PATVDAAVPGAG-------KKRYPTAEEILVLGGYLRLSRSCLAKGSPERHHKQLKISFS 543
Query: 521 DKSLQTTFEYPSESS----LEQEEEVDQQEEEEEEEEEEEEEEE 560
+ +L+TT++YPSESS L E EV + ++EE+EE
Sbjct: 544 ETALETTYQYPSESSVLEELGPEPEVPSAPNPPAAQPDDEEDEE 587
Score = 43.1 bits (100), Expect = 8e-04
Identities = 24/60 (40%), Positives = 29/60 (48%), Gaps = 14/60 (23%)
Query: 97 PPPPPPPAPPRPPPAAPSPPAAP-------GPRGGGASPGARRSDFLQKTGSNSFTVHPR 149
PPPP P +PP P P AP PP P G + G RRS ++FTV+PR
Sbjct: 425 PPPPAPLSPPPPAPTAPQPPGDPLMSRLFYGVKAGPGVGAPRRS-------GHTFTVNPR 477
Score = 34.3 bits (77), Expect = 0.39
Identities = 41/135 (30%), Positives = 47/135 (34%), Gaps = 29/135 (21%)
Query: 4 EAERRRGGGAAGA-RLLERYRRVP--------GVRALRADSVLIIETVPGFP----PAPP 50
EAE+ G R L+ VP G LR +E P P P PP
Sbjct: 377 EAEKEEAGAQGRPLRALQNCCSVPSPLPPEDAGTGGLRQQEEEAVELQPPPPAPLSPPPP 436
Query: 51 APGAAQIRAAEVLVYGAPPGR--VSRL---LERFDPPAAPRRRGSPERARPPPPPPPPAP 105
AP A Q PPG +SRL ++ APRR G P PP P
Sbjct: 437 APTAPQ-----------PPGDPLMSRLFYGVKAGPGVGAPRRSGHTFTVNPRRSVPPATP 485
Query: 106 PRPPPAAPSPPAAPG 120
P A A PG
Sbjct: 486 ATPTSPATVDAAVPG 500
>gi|199559805 phostensin [Homo sapiens]
Length = 613
Score = 82.0 bits (201), Expect = 2e-15
Identities = 60/164 (36%), Positives = 81/164 (49%), Gaps = 21/164 (12%)
Query: 405 APQAAKLPYLPHPARPLHPARPGCVAELQPRGSNTFTVVPKRK--PGTLQDQHFSQANRE 462
AP A + P P +R + + G R +TFTV P+R P T
Sbjct: 437 APTAPQPPGDPLMSRLFYGVKAGPGVGAPRRSGHTFTVNPRRSVPPAT------PATPTS 490
Query: 463 PRPREAEEEEASCLLGPTLKKRYPTVHEIEVIGGYLALQKSCLTKAGSSR--KKMKISFN 520
P +A A KKRYPT EI V+GGYL L +SCL K R K++KISF+
Sbjct: 491 PATVDAAVPGAG-------KKRYPTAEEILVLGGYLRLSRSCLAKGSPERHHKQLKISFS 543
Query: 521 DKSLQTTFEYPSESS----LEQEEEVDQQEEEEEEEEEEEEEEE 560
+ +L+TT++YPSESS L E EV + ++EE+EE
Sbjct: 544 ETALETTYQYPSESSVLEELGPEPEVPSAPNPPAAQPDDEEDEE 587
Score = 43.1 bits (100), Expect = 8e-04
Identities = 24/60 (40%), Positives = 29/60 (48%), Gaps = 14/60 (23%)
Query: 97 PPPPPPPAPPRPPPAAPSPPAAP-------GPRGGGASPGARRSDFLQKTGSNSFTVHPR 149
PPPP P +PP P P AP PP P G + G RRS ++FTV+PR
Sbjct: 425 PPPPAPLSPPPPAPTAPQPPGDPLMSRLFYGVKAGPGVGAPRRS-------GHTFTVNPR 477
Score = 34.3 bits (77), Expect = 0.39
Identities = 41/135 (30%), Positives = 47/135 (34%), Gaps = 29/135 (21%)
Query: 4 EAERRRGGGAAGA-RLLERYRRVP--------GVRALRADSVLIIETVPGFP----PAPP 50
EAE+ G R L+ VP G LR +E P P P PP
Sbjct: 377 EAEKEEAGAQGRPLRALQNCCSVPSPLPPEDAGTGGLRQQEEEAVELQPPPPAPLSPPPP 436
Query: 51 APGAAQIRAAEVLVYGAPPGR--VSRL---LERFDPPAAPRRRGSPERARPPPPPPPPAP 105
AP A Q PPG +SRL ++ APRR G P PP P
Sbjct: 437 APTAPQ-----------PPGDPLMSRLFYGVKAGPGVGAPRRSGHTFTVNPRRSVPPATP 485
Query: 106 PRPPPAAPSPPAAPG 120
P A A PG
Sbjct: 486 ATPTSPATVDAAVPG 500
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 71.6 bits (174), Expect = 2e-12
Identities = 60/197 (30%), Positives = 78/197 (39%), Gaps = 41/197 (20%)
Query: 43 PGFPPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPP-- 100
PG P PP G + ++A +PPG+ P P +G + PPPPP
Sbjct: 218 PGKPQGPPPQGDNKSQSAR-----SPPGK----------PQGPPPQGGNQPQGPPPPPGK 262
Query: 101 ---PPPA----PPRPPPAAPSPPAAPGPRGGGAS------PGARRSDFLQKTGSNSFTVH 147
PPP P PPP P P P P+GG S PG + Q
Sbjct: 263 PQGPPPQGGNKPQGPPP--PGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPP 320
Query: 148 PRGLHRGAGARLLSNGHS--------APEPRAGPANRLAGSPPGSGQWKPKVESGDPSLH 199
P G +G + + P P+ G +R A SPPG Q P+ E +P
Sbjct: 321 PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGP 380
Query: 200 PPPSPGTPSATPASPPA 216
PPP+ G P P +PPA
Sbjct: 381 PPPAGGNPQ-QPQAPPA 396
Score = 68.6 bits (166), Expect = 2e-11
Identities = 79/319 (24%), Positives = 106/319 (33%), Gaps = 58/319 (18%)
Query: 46 PPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPAP 105
P PP PG Q G PP ++ PP P+ +P PPPPP
Sbjct: 150 PQGPPPPGKPQ---------GPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGK 200
Query: 106 PR-PPPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGH 164
P+ PPP + P P P G P P+G ++ AR
Sbjct: 201 PQGPPPQGGNKPQGPPPPGKPQGPP------------------PQGDNKSQSARSPPGKP 242
Query: 165 SAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTPSATP----ASPPASATP 220
P P+ G N+ G PP G+ + G PP PG P P + +S +P
Sbjct: 243 QGPPPQGG--NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSP 300
Query: 221 SQRQCVSAATSTNDSFEIRPAPKPVMETIPLGDLQARALASLRANSRNSFMVIPKSKASG 280
+ N P P P G + + P K G
Sbjct: 301 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP-------------PPGKPQG 347
Query: 281 APPPEGRQSVELPKGDLGPASPSQELGSQPVPGGDGAPALGKSPLEVEAQWAVEEGACPR 340
PP G +S P P Q+ G+ P G PA G +P + +A A + PR
Sbjct: 348 PPPQGGSKSRSARSPPGKPQGPPQQEGNN--PQGPPPPA-GGNPQQPQAPPAGQPQGPPR 404
Query: 341 TATALADRAIRWQRPSSPP 359
+ RPS PP
Sbjct: 405 PP--------QGGRPSRPP 415
Score = 67.8 bits (164), Expect = 3e-11
Identities = 83/346 (23%), Positives = 111/346 (32%), Gaps = 73/346 (21%)
Query: 43 PGFPPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPP 102
PG P PP G Q + PPG+ + P + +G P +P PPP
Sbjct: 54 PGKPQGPPPQGGNQPQGPP-----PPPGKP----QGPPPQGGNKPQGPPPPGKPQGPPPQ 104
Query: 103 PAPPRPPPAAPSPPAAPGPRGG----GASPGARRSDFLQKTGSNSFTVHPRGLHRGAGAR 158
R P + P P P P+GG G P + G N P+G +
Sbjct: 105 GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK----PQGPPPPGKPQ 160
Query: 159 LLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTPSATP---ASPP 215
P P+ +R + SPPG Q P + G+ PPP PG P P + P
Sbjct: 161 -------GPPPQGDNKSRSSRSPPGKPQGPPP-QGGNQPQGPPPPPGKPQGPPPQGGNKP 212
Query: 216 ASATPSQRQCVSAATSTNDSFEIRPAPKPVMETIPLGDLQARALASLRANSRNSFMVIPK 275
P + N S R P P G Q +
Sbjct: 213 QGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQ------------------ 254
Query: 276 SKASGAPPPEGRQSVELPKG---DLGPASPSQELGSQPVPGGDGAPALGKSPLEVEAQWA 332
G PPP G+ P+G GP P + G P P G +SP
Sbjct: 255 ----GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG--PPPQGGSKSRSSRSPP------G 302
Query: 333 VEEGACPRTATALADRAIRWQRPSSPPPFLPAASEEAEPAEGLRVP 378
+G P+ +P PPP P + P +G P
Sbjct: 303 KPQGPPPQGG----------NQPQGPPP--PPGKPQGPPPQGGNKP 336
Score = 63.5 bits (153), Expect = 6e-10
Identities = 75/312 (24%), Positives = 97/312 (31%), Gaps = 85/312 (27%)
Query: 80 DPPAAPRRRGSPERARPPPPPPPPAPP-------RPPPAAPSPPAAPGPRGGGASPGARR 132
+P AP + G+ + P PP P PP + PP P P P P+GG G
Sbjct: 35 NPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP-- 92
Query: 133 SDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVE 192
P G +G P G +R SPPG Q P +
Sbjct: 93 --------------PPPGKPQG-------------PPPQGDKSRSPRSPPGKPQGPPP-Q 124
Query: 193 SGDPSLHPPPSPGTPSATP---ASPPASATPSQRQCVSAATSTNDSFEIRPAPKPVMETI 249
G+ PPP PG P P + P P + N S R P
Sbjct: 125 GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPP 184
Query: 250 PLGDLQARALASLRANSRNSFMVIPKSKASGAPPPEGRQSVELPKG---DLGPASPSQEL 306
P G Q + G PPP G+ P+G GP P +
Sbjct: 185 PQGGNQPQ----------------------GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ 222
Query: 307 GSQPVPGGDGAPALGKSPLEVEAQWAVEEGACPRTATALADRAIRWQRPSSPPPFLPAAS 366
G P P GD +SP +G P+ +P PPP P
Sbjct: 223 G--PPPQGDNKSQSARSPP------GKPQGPPPQGG----------NQPQGPPP--PPGK 262
Query: 367 EEAEPAEGLRVP 378
+ P +G P
Sbjct: 263 PQGPPPQGGNKP 274
Score = 60.8 bits (146), Expect = 4e-09
Identities = 51/178 (28%), Positives = 65/178 (36%), Gaps = 51/178 (28%)
Query: 43 PGFPPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPP-- 100
PG P PP G ++ R++ +PPG+ P P +G + PPPPP
Sbjct: 280 PGKPQGPPPQGGSKSRSSR-----SPPGK----------PQGPPPQGGNQPQGPPPPPGK 324
Query: 101 ---PPPA----PPRPPPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHR 153
PPP P PPP P P P P+GG S AR P G +
Sbjct: 325 PQGPPPQGGNKPQGPPP--PGKPQGPPPQGGSKSRSARS---------------PPGKPQ 367
Query: 154 GAGARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTPSATP 211
G + +N P P G + P G Q P+ PP G PS P
Sbjct: 368 GPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPR----------PPQGGRPSRPP 415
Score = 40.4 bits (93), Expect = 0.005
Identities = 55/227 (24%), Positives = 72/227 (31%), Gaps = 53/227 (23%)
Query: 159 LLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTPSATPA----SP 214
+ N AP P+ G + SPPG Q P + G+ PPP PG P P P
Sbjct: 32 IAGNPQGAP-PQGGNKPQGPPSPPGKPQGPPP-QGGNQPQGPPPPPGKPQGPPPQGGNKP 89
Query: 215 PASATPSQRQCVSAATSTNDSFEIRPAPKPVMETIPLGDLQARALASLRANSRNSFMVIP 274
P + Q + S R P P G Q +
Sbjct: 90 QGPPPPGKPQ--GPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQ----------------- 130
Query: 275 KSKASGAPPPEGRQSVELPKG---DLGPASPSQELGSQPVPGGDGAPALGKSPLEVEAQW 331
G PPP G+ P+G GP P + G P P GD +SP
Sbjct: 131 -----GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG--PPPQGDNKSRSSRSPP------ 177
Query: 332 AVEEGACPRTATALADRAIRWQRPSSPPPFLPAASEEAEPAEGLRVP 378
+G P+ +P PPP P + P +G P
Sbjct: 178 GKPQGPPPQGG----------NQPQGPPP--PPGKPQGPPPQGGNKP 212
>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
sapiens]
Length = 247
Score = 69.7 bits (169), Expect = 8e-12
Identities = 66/205 (32%), Positives = 73/205 (35%), Gaps = 56/205 (27%)
Query: 43 PGFPPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPP---- 98
PG P PP G Q + G P GR + + P P G PER PPP
Sbjct: 54 PGKPQGPPPQGGNQSQGPPPPP-GKPEGRPPQGGNQSQGP--PPHPGKPER--PPPQGGN 108
Query: 99 -----PPPPPAPPRPPPAA----------PSPPAAPGPRGGGASPGARRSDFLQKTGSNS 143
PPPP P RPPP P P P P+GG S G
Sbjct: 109 QSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGP------------- 155
Query: 144 FTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPS 203
HP G G P P+ G +R A SPPG Q P+ E P PP
Sbjct: 156 -PPHP-GKPEG------------PPPQEGNKSRSARSPPGKPQGPPQQEGNKP--QGPPP 199
Query: 204 PGTPSATPASPPASATPSQRQCVSA 228
PG P PPA P Q Q A
Sbjct: 200 PGKPQ---GPPPAGGNPQQPQAPPA 221
Score = 64.7 bits (156), Expect = 3e-10
Identities = 76/306 (24%), Positives = 95/306 (31%), Gaps = 104/306 (33%)
Query: 82 PAAPRRRGSPERARPPPPPPPPAPPRP--------PPAAPSPPAAPGPRGGGASPGARRS 133
P R +G + RPPPPP P P P PP P P P+GG S G
Sbjct: 36 PEGRRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGP--- 92
Query: 134 DFLQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSPPGSGQ-WKPKVE 192
HP R P P+ G N+ G+PP G+ +P +
Sbjct: 93 -----------PPHPGKPER-------------PPPQGG--NQSQGTPPPPGKPERPPPQ 126
Query: 193 SGDPSLHPPPSPGTPSATPASPPASATPSQRQCVSAATSTNDSFEIRPAPKPVMETIPLG 252
G+ S PPP PG P P P SQ P P P
Sbjct: 127 GGNQSHRPPPPPGKPERPP---PQGGNQSQG----------------PPPHP-------- 159
Query: 253 DLQARALASLRANSRNSFMVIPKSKASGAPPPEGRQSVELPKGDLGPASPSQELGSQPVP 312
K G PP EG +S P P Q+ G++P
Sbjct: 160 -----------------------GKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKP-- 194
Query: 313 GGDGAPALGKSPLEVEAQWAVEEGACPRTATALADRAIRWQRPSSPPPFLPAASEEAEPA 372
G P GK +G P +A +P PPP P PA
Sbjct: 195 --QGPPPPGK-----------PQGPPPAGGNPQQPQAPPAGKPQGPPP-PPQGGRPPRPA 240
Query: 373 EGLRVP 378
+G + P
Sbjct: 241 QGQQPP 246
Score = 46.2 bits (108), Expect = 1e-04
Identities = 27/85 (31%), Positives = 33/85 (38%), Gaps = 3/85 (3%)
Query: 43 PGFPPAPPAPGAAQIRAAEV---LVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPP 99
PG P PP G Q + G PP ++ PP P+ E +P P
Sbjct: 138 PGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGP 197
Query: 100 PPPPAPPRPPPAAPSPPAAPGPRGG 124
PPP P PPPA +P P G
Sbjct: 198 PPPGKPQGPPPAGGNPQQPQAPPAG 222
Score = 39.3 bits (90), Expect = 0.012
Identities = 29/94 (30%), Positives = 39/94 (41%), Gaps = 23/94 (24%)
Query: 43 PGFPPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPP 102
PG P PP + R+A +PPG+ P P++ G+ + PPPP P
Sbjct: 159 PGKPEGPPPQEGNKSRSAR-----SPPGK---------PQGPPQQEGNKPQG-PPPPGKP 203
Query: 103 PAP------PRPPPAAPS--PPAAPGPRGGGASP 128
P P+ P A P+ P P P GG P
Sbjct: 204 QGPPPAGGNPQQPQAPPAGKPQGPPPPPQGGRPP 237
Score = 32.0 bits (71), Expect = 1.9
Identities = 23/70 (32%), Positives = 25/70 (35%), Gaps = 17/70 (24%)
Query: 46 PPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPAP 105
P PP PG Q PP + PPA G P+ PPPPP P
Sbjct: 194 PQGPPPPGKPQ----------GPPPAGGNPQQPQAPPA-----GKPQG--PPPPPQGGRP 236
Query: 106 PRPPPAAPSP 115
PRP P
Sbjct: 237 PRPAQGQQPP 246
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 69.3 bits (168), Expect = 1e-11
Identities = 118/489 (24%), Positives = 160/489 (32%), Gaps = 82/489 (16%)
Query: 6 ERRRGGGAAGARLLERYRRVPGVRALRADSVLIIETVPGFPPAPP--APGAAQIRAAEVL 63
+ +R AGA R PG L+ PG P PP P A ++ A
Sbjct: 2 DNKRDKAKAGAAARTPAARAPG---------LLTPRPPGSPRPPPPVTPAALRVLGAAGA 52
Query: 64 VYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPAPPRPPPAAPSPPAAPGPRG 123
V P + + P + R G +RPP P +P P ++PG
Sbjct: 53 VGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRAS 112
Query: 124 GGASPG-----ARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHS--APEPRAGPANR 176
G PG R + T P+ AGAR ++G + P P +R
Sbjct: 113 GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR 172
Query: 177 LAGS--------------PPGSGQWKPKVESGDPSLHPP-------PSPG---------- 205
AG+ PP G K + + S P PS G
Sbjct: 173 AAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 232
Query: 206 -TPSATPASPPASATPSQRQCVSAATSTNDSFEIRPAPKPVMETIP-------------L 251
+ SATP S PA + PS R T + +P PK + P L
Sbjct: 233 LSSSATPLSSPARSGPSAR-----GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 287
Query: 252 GDLQARALASLRANSRNSFMVIPKSKASGAPP--PEGRQSVELPKGDLGPAS---PSQEL 306
G L + LA+ ++ S P + +PP P + + L L PS L
Sbjct: 288 GPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPL 347
Query: 307 GSQPVPGGDGAPALGKSPLEVEAQWAVEEGACP-RTATALADRAIR---WQRPSSPPPFL 362
P PAL PL+ P T + A A+ Q P SPPP
Sbjct: 348 SPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 407
Query: 363 PAASEEAEPAEGLRVPGLAKNSR---EYVRPGLPVTFIDEVDSEEAPQAAKLPYLPHP-- 417
P + + PA P S+ P L V +P A P P P
Sbjct: 408 PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 467
Query: 418 ARPLHPARP 426
A PL A+P
Sbjct: 468 APPLQLAKP 476
Score = 59.3 bits (142), Expect = 1e-08
Identities = 96/354 (27%), Positives = 126/354 (35%), Gaps = 72/354 (20%)
Query: 43 PGFPPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERA--RPPPPP 100
P PP+P AP + Q + PP + + L A SP + PPP
Sbjct: 300 PSAPPSPSAPPSLQTLPSPP---ATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQ 356
Query: 101 PPPAPPRPP-PAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARL 159
PPA PP A PSPPA+P P A+P + N+ VH L
Sbjct: 357 APPALALPPLQAPPSPPASP-PLSPLATPSPQ--------APNALAVH-----------L 396
Query: 160 LSNGHSAPEPRAGPANRLAGSPPGSGQWKPKV---ESGDPSLHPPPSPGTPSATPASPP- 215
L S P P + SPP S P PSL PP P + PASPP
Sbjct: 397 LQAPFSPP---PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ-VPPSPPASPPM 452
Query: 216 -ASATPSQRQCVSAATSTNDSFEIRPAPKPVMETIPLGDLQARALASLRANSRNSFMVIP 274
SATP + A + P P + T PL L + + + +P
Sbjct: 453 SPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 512
Query: 275 KSKASGAPPPEGRQSVELPKGDLGPASPS----QELGSQPVPGGDGAPALGKSPLEVEAQ 330
S + PPP+ + P + P+ P+ Q P PG D +
Sbjct: 513 MSPLA-TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV------------ 559
Query: 331 WAVEEGACPRTATALADRAIRWQRPSSPPPFLPAASEEAEPAEGLRVPGLAKNS 384
+ PR ALA P PPP P+ S P+ L P LA +S
Sbjct: 560 ------SGPRLTLALA--------PGPPPP--PSRS----PSSTLSGPDLAGHS 593
Score = 58.2 bits (139), Expect = 3e-08
Identities = 85/337 (25%), Positives = 123/337 (36%), Gaps = 62/337 (18%)
Query: 26 PGVRALRADSVLIIETVPGFPPAPPA------PGAAQIRAAEVLVYGAPPGRVSRLLERF 79
P +A A +V +++ PP+PP P + + + APP + L+
Sbjct: 384 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV- 442
Query: 80 DPPAAPRRRGSPERARPPPPPPPP--APP----RPPPAAPSPPAAPGPRGGGASPGARRS 133
PP+ P A PPP PPP APP +PPP AP P A P SP A
Sbjct: 443 -PPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP-PALATPPLQALPSPPASFP 500
Query: 134 DFLQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVES 193
+ S S + P L + AP A P ++ SPP S
Sbjct: 501 GQAPFSPSASLPMSP----------LATPPPQAPPVLAAPLLQVPPSPPAS--------- 541
Query: 194 GDPSLHPPPSPGTPSATPASPPASATPSQRQCVSAATSTNDSFEIRPAPKPVMETIPLGD 253
P+L P P TP P ++ R ++ A P P P P
Sbjct: 542 --PTLQAPRRPPTPG------PDTSVSGPRLTLALA----------PGPPPPPSRSPSST 583
Query: 254 LQARALASLRANSRNS------FMVIPKSKASGAPPPEGRQSVELPKG-DLGPASPSQEL 306
L LA +++ ++ + P+ A+ +PPP+ + P GPA P
Sbjct: 584 LSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFR 643
Query: 307 GSQPVPGGDGAPALGKSPLEVEAQWAVEEGACPRTAT 343
G+ P PA G P + + E P +AT
Sbjct: 644 GAPGAP-LPWPPATG--PGSADGLCTIYETEGPESAT 677
Score = 45.8 bits (107), Expect = 1e-04
Identities = 83/304 (27%), Positives = 105/304 (34%), Gaps = 75/304 (24%)
Query: 31 LRADSVLIIETVPGFPPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFD----PPAAPR 86
L A + + + P PPA P + + G P S L PP AP
Sbjct: 466 LAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 525
Query: 87 RRGSPERARPPPPPPPP---APPRPPPAAPSPPAAPGPR-----GGGASPGARRSDFLQK 138
+P PP PP P AP RPP P + GPR G P RS
Sbjct: 526 VLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVS-GPRLTLALAPGPPPPPSRSPSSTL 584
Query: 139 TG------SNSFTVHPRGLHRGAGARLLSNGHSAPEPRA------------GPANRLA-- 178
+G S+S T P L RG + ++P P A GPA LA
Sbjct: 585 SGPDLAGHSSSATSTPEEL-RGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFR 643
Query: 179 GSPPGSGQWKPKV-----------------ESGDPS---LHPPPSPGTPSATPASPPASA 218
G+P W P ES P+ L P PSPGT S A+ A A
Sbjct: 644 GAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGT-SGGKAAAGAGA 702
Query: 219 TPSQRQCVSAATSTNDSFEIRPAPKPV-METIPLGDLQARALASLRANSRNSFMVIPKSK 277
S R +PK + +PLG LQA + L SR + +
Sbjct: 703 GASSR-----------------SPKQARLGELPLGALQASVVQHLL--SRTLLLAAAEGA 743
Query: 278 ASGA 281
A G+
Sbjct: 744 AGGS 747
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 68.9 bits (167), Expect = 1e-11
Identities = 68/205 (33%), Positives = 85/205 (41%), Gaps = 32/205 (15%)
Query: 47 PAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPP------ 100
P P APG I+ + APP + PPAAP +P A PPPPP
Sbjct: 229 PKPAAPGTV-IQTPPFVGAAAPPAPAAP-----SPPAAPAP-AAPAAAPPPPPPAPATLA 281
Query: 101 -PPPAPPRPPPAAPS-PPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGAR 158
PP P PP AAP+ PP A GG A GA + G + P GA A
Sbjct: 282 RPPGHPAGPPTAAPAVPPPAAAQNGGSA--GAAPAPAPAAGGPAGVSGQPGP---GAAAA 336
Query: 159 LLSNGHSAPEPR----AGP--ANRLAGSPPGSGQWK----PKVESG--DPSLHPPPSPGT 206
+ G A P+ A P A LA S P S P ++ P+ PPP+PGT
Sbjct: 337 APAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGT 396
Query: 207 PSATPASPPASATPSQRQCVSAATS 231
P+ P + T S + +A TS
Sbjct: 397 PTGLPKGAAGAVTQSLSRTPTATTS 421
Score = 61.2 bits (147), Expect = 3e-09
Identities = 133/521 (25%), Positives = 169/521 (32%), Gaps = 139/521 (26%)
Query: 24 RVPGVRALRADSV--LIIETVP----GFPPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLE 77
R P VRA A ++ ++ P G PA PA GA GA P
Sbjct: 46 RTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAP----------GAAPE------- 88
Query: 78 RFDPPAAPRRRGSPERARPPPP-------PPPPAPP----RPPPAAPSPPAAPGPRGGGA 126
PPA R G RP PP P PAPP RPPP + AP P
Sbjct: 89 --PPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAV 146
Query: 127 SPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSPPGSGQ 186
+ G + P G + AG L+ + P P GP G PG G
Sbjct: 147 AAGPEPA--------------PAGPAKPAGPAALA-ARAGPGPGPGP-----GPGPGPGP 186
Query: 187 WKPK---------------------------VESGDPSLHP---PPSPGTPSATP----- 211
KP V +G +L P P +PGT TP
Sbjct: 187 GKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGA 246
Query: 212 ASPPASATPSQRQCVSAATSTNDSFEIRPAPKPVMETI------PLGDLQARALASLRAN 265
A+PPA A PS AA + P P P T+ P G A A
Sbjct: 247 AAPPAPAAPSP----PAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAA 302
Query: 266 SRNSFMVIPKSKASGAPPPEGRQSVELPKGDLGPASPSQELGSQPVPG-GDGAPALGKSP 324
++N A AP P GPA S QP PG APA G
Sbjct: 303 AQNG------GSAGAAPAPAPAAG--------GPAGVS----GQPGPGAAAAAPAPG--- 341
Query: 325 LEVEAQWAVEEGACPRTATALADRAIRWQRPSSPPP----FLPAASEEAEPAEGLRVPGL 380
++ E+ V + A P T A P LP+ + PA G GL
Sbjct: 342 VKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPT-GL 400
Query: 381 AKNSREYVRPGLPVTFIDEVDSEEAPQAAKLPYLPHPARPLHPARPGCVAELQ-PRG--- 436
K + V L T + +A P + P P P P + Q P G
Sbjct: 401 PKGAAGAVTQSLSRT---PTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVL 457
Query: 437 ----SNTFTVVPKRKPGTLQDQHFSQANREPRPREAEEEEA 473
+ ++P++ +Q Q +Q PR A A
Sbjct: 458 VRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSA 498
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 67.4 bits (163), Expect = 4e-11
Identities = 90/354 (25%), Positives = 128/354 (36%), Gaps = 52/354 (14%)
Query: 26 PGVRALRADSVLIIETVPGFPPAPPA------PGAAQIRAAEVLVYGAPPGRVSRLLERF 79
P +A A +V +++ PP+PP P + + + APP + L+
Sbjct: 648 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV- 706
Query: 80 DPPAAPRRRGSPERARPPPPPPPPAPPRPPPAAPSPPAAPGPRGGGASPGARRSDFLQKT 139
PP+ P A PPP PPP P PSPPA+P P A+P R L
Sbjct: 707 -PPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP-PMSPSATPPPRVPPLL--- 761
Query: 140 GSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSP-----------PGSGQWK 188
P + A L + + P P+A PA LA P PG +
Sbjct: 762 -----AAPPLQVPPSPPASLPMSPLAKPPPQAPPA--LATPPLQALPSPPASFPGQAPFS 814
Query: 189 PKVESGDPSLHPPPSPGTP------SATPASPPASAT---PSQRQCVSAATSTND---SF 236
P L PP P P SPPAS T P + TS + +
Sbjct: 815 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL 874
Query: 237 EIRPAPKPVMETIPLGDLQARALASLRANSRNS------FMVIPKSKASGAPPPEGRQSV 290
+ P P P P L LA +++ ++ + P+ A+ +PPP+ +
Sbjct: 875 ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA 934
Query: 291 ELPKG-DLGPASPSQELGSQPVPGGDGAPALGKSPLEVEAQWAVEEGACPRTAT 343
P GPA P G+ P PA G P + + E P +AT
Sbjct: 935 CHPAAWSRGPAPPLAFRGAPGAP-LPWPPATG--PGSADGLCTIYETEGPESAT 985
Score = 63.2 bits (152), Expect = 8e-10
Identities = 100/354 (28%), Positives = 131/354 (37%), Gaps = 68/354 (19%)
Query: 49 PPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPE-RARPPPP------PP 101
PP P ++A + PP S + PP AP SP + P PP PP
Sbjct: 561 PPCPAPCPLQAPPSPLTTPPPETPSSIAT--PPPQAPPALASPPLQGLPSPPLSPLATPP 618
Query: 102 PPAPPR----PPPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGA 157
P APP P A PSPPA+P P A+P + N+ VH L + +
Sbjct: 619 PQAPPXLALPPLQAPPSPPASP-PLSPLATPSPQ--------APNALAVH---LLQAPFS 666
Query: 158 RLLSNGHSAP-EPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPG-----TPSAT- 210
S AP P A P + +PP Q P + + P L PPSP +PSAT
Sbjct: 667 PPPSPPVQAPFSPPASPPVSPSATPP--SQAPPSLAA--PPLQVPPSPPASPPMSPSATP 722
Query: 211 -PASPPASATPSQRQCVSAATSTNDSFEIRPAPK--PVMETIPLGDLQARALASLRANSR 267
P +PP A P + S S S P P+ P++ PL + +
Sbjct: 723 PPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPL---------QVPPSPP 773
Query: 268 NSFMVIPKSKASGAPPPEGRQSVELPKGDLGPASPSQELGSQPVPGGDGAPALGKSPLEV 327
S + P +K PPP+ ++ P P Q L S P A G++P
Sbjct: 774 ASLPMSPLAK----PPPQAPPALATP--------PLQALPSPP------ASFPGQAPFSP 815
Query: 328 EAQWAVEEGACPRTATALADRAIRWQRPSSPP--PFLPAASEEAEPAEGLRVPG 379
A + A P A Q P SPP P L A P V G
Sbjct: 816 SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 869
Score = 58.5 bits (140), Expect = 2e-08
Identities = 114/452 (25%), Positives = 154/452 (34%), Gaps = 82/452 (18%)
Query: 6 ERRRGGGAAGARLLERYRRVPGVRALRADSVLIIETVPGFPPAPPAPGAAQIRAAEVLVY 65
+ +R AGA R PG L+ PG P PP A +R V
Sbjct: 2 DNKRDKAKAGAAARTPAARAPG---------LLTPRPPGSPRPPPPVTPAALR-----VL 47
Query: 66 GAPPGRVSR--LLERFD-------PPAAPRR---RGSPERARPPPPPPPPAP--PRPPPA 111
GA G V R L ER P +APR R + +R P PP + R PPA
Sbjct: 48 GAA-GAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPA 106
Query: 112 ---APSPPAAPGPRGGGASPG-----ARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNG 163
+P P ++PG G PG R + T P+ AGAR ++G
Sbjct: 107 KNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG 166
Query: 164 HS--APEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATPS 221
+ P P +R AG+ G P P++ P T
Sbjct: 167 PTPGTPSPAMARRSRAAGT----------------------EVGLPRPAPSARPRPPTEG 204
Query: 222 QRQCVSAATSTNDSFEIRPAPKPVMETIPLGDLQARALASLRANSRN-SFMVIPKSKASG 280
R+ VS+A+ + + P+P G LQ A SL +++ S A G
Sbjct: 205 PRKSVSSASEHSTT---EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG 261
Query: 281 APPPEGRQSVELPKGDLGPASPSQELGSQPVPGGDGAPALG---KSPLEVEAQWAV---- 333
P S PKG L P Q P D APALG SPL +
Sbjct: 262 TPRAPAHPSQPKPKG-LQALRPPQ----VTPPRKDAAPALGPLSSSPLATPSPSGTKARP 316
Query: 334 ----EEGACPRTATALADRAIRWQRPSSPPPFLPAASEEAEPAEGLRVPGLAKNSREYVR 389
+ A P AT + P +PP S + P+ P A S
Sbjct: 317 VPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPP 376
Query: 390 PGLPVTFIDEVDSEEAPQAAKLPYLPHPARPL 421
P + + + + P + P L P PL
Sbjct: 377 MQAPPS-LQTIPPIQVPHSLTSPSLQAPPSPL 407
Score = 55.8 bits (133), Expect = 1e-07
Identities = 93/344 (27%), Positives = 118/344 (34%), Gaps = 59/344 (17%)
Query: 46 PPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLER-FDPPAAPRRRGSPERAR-PPPPPPPP 103
PP+PPA + + AP LL+ F PP +P P +A PP PP
Sbjct: 633 PPSPPA--SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP-----PVQAPFSPPASPPV 685
Query: 104 APPRPPPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNG 163
+P PP+ P A P SP A S S T P+
Sbjct: 686 SPSATPPSQAPPSLAAPPLQVPPSPPA------SPPMSPSATPPPQ-------------- 725
Query: 164 HSAPEPRAGPANRLAGSPPGSGQWKPKVES--------GDPSLHPPPSPG-----TPSA- 209
AP P A P ++ SPP S P P L PPSP +P A
Sbjct: 726 --APPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAK 783
Query: 210 -TPASPPASATPSQRQCVSAATSTNDSFEIRPAPKPVMETIPLGDLQA-RALASLRANSR 267
P +PPA ATP + S S P+ M + QA LA+
Sbjct: 784 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 843
Query: 268 NSFMVIPKSKASGAPPPEGRQ-SVELPKGDL----GPASPSQELGSQPVPGGDGA---PA 319
S P +A PP G SV P+ L GP P S + G D A +
Sbjct: 844 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 903
Query: 320 LGKSPLEVEAQWAVEEGAC----PRTATALADRAIRWQRPSSPP 359
+P E+ + EG P A A W R +PP
Sbjct: 904 ATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPP 947
Score = 54.3 bits (129), Expect = 4e-07
Identities = 122/514 (23%), Positives = 152/514 (29%), Gaps = 128/514 (24%)
Query: 24 RVPGVRALRADSVLIIETVPGFPPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPP- 82
R P V R D+ + + P A P+P + R PP + L PP
Sbjct: 281 RPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVP------PPDNAATPLPATLPPS 334
Query: 83 ---AAPRRRGSPERARPP-----PPPPPPAPPRPPPAAPSPPAAPGPR------------ 122
A P P + PP P PP P + PP+ +PP P
Sbjct: 335 PPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHS 394
Query: 123 ----GGGASPGARRSDFLQKTGS---------NSF-TVHPRGLHRGAGARLLSNGHSAPE 168
A P LQ T S +SF T+ PR A L S A
Sbjct: 395 LTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQ----ASLTSPSRPAST 450
Query: 169 PRAGPANR----LAGSPPGSGQWKPKVE--SGDPSLHP---------------------- 200
P P + L SPP P V S ++HP
Sbjct: 451 PPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMP 510
Query: 201 ---------PPSPGTPSATPASPPASATPSQRQ---CVSAATSTNDSFEIRPAPKPVMET 248
PPS TP A+ +PP PS ++A T E P P P
Sbjct: 511 PLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQ 570
Query: 249 IPLGDLQARALASLRANSRNSFMVIPKSKASGAPPPEGRQSVELPKGDLGPA---SPSQE 305
P L PPPE S+ P PA P Q
Sbjct: 571 APPSPLT-------------------------TPPPETPSSIATPPPQAPPALASPPLQG 605
Query: 306 LGSQPV-----PGGDGAPALGKSPLEVEAQWAVEEGACP-RTATALADRAIR---WQRPS 356
L S P+ P P L PL+ P T + A A+ Q P
Sbjct: 606 LPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 665
Query: 357 SPPPFLPAASEEAEPAEGLRVPGLAKNSR---EYVRPGLPVTFIDEVDSEEAPQAAKLPY 413
SPPP P + + PA P S+ P L V +P A P
Sbjct: 666 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 725
Query: 414 LPHP--ARPLH-PARPGCVAELQPRGSNTFTVVP 444
P P A PL P P + P + V P
Sbjct: 726 APPPLAAPPLQVPPSPPASPPMSPSATPPPRVPP 759
Score = 50.1 bits (118), Expect = 7e-06
Identities = 90/362 (24%), Positives = 123/362 (33%), Gaps = 76/362 (20%)
Query: 99 PPPPPAPPRPPPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGAR 158
P PP +P PPP P+ R GA+ R ++ G P R R
Sbjct: 27 PRPPGSPRPPPPVTPA-----ALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR 81
Query: 159 LLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPP--- 215
S G S+ P A PP SG+ + + + S P SPG S T P
Sbjct: 82 --SAGTSSRNP--------ASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQ 131
Query: 216 ---------------ASATPSQRQCVSAATSTNDSFEIRPAPKPVMETIPLGDLQARALA 260
A+ P +R +SA + S P P M
Sbjct: 132 KGLRISAEETVARGKATEAP-KRSALSAGARRDTSGPTPGTPSPAM------------AR 178
Query: 261 SLRANSRNSFMVIPKSKASGAPPPEG-RQSVELPKGDLGPASPSQELGSQPVPGGDGAPA 319
RA + P A PP EG R+SV +S S+ ++P P P+
Sbjct: 179 RSRAAGTEVGLPRPAPSARPRPPTEGPRKSV---------SSASEHSTTEPSPAARRRPS 229
Query: 320 LGKSPLEVEAQWAVEEGACPRTATALADRAIRW-----QRPSSP---------PPFLPAA 365
G L+ A ++ A P ++ A + + R PS P PP +
Sbjct: 230 AG-GGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP 288
Query: 366 SEEAEPAEG-LRVPGLAKNSREYVRPGLPVTFIDEVDSEEAPQAAKLPYLPHPARPLHPA 424
++A PA G L LA S G + D+ P A LP P A PL A
Sbjct: 289 RKDAAPALGPLSSSPLATPSPS----GTKARPVPPPDNAATPLPATLPPSPPLATPLPLA 344
Query: 425 RP 426
P
Sbjct: 345 PP 346
Score = 47.8 bits (112), Expect = 3e-05
Identities = 94/371 (25%), Positives = 127/371 (34%), Gaps = 41/371 (11%)
Query: 81 PPAAPRRRGSPERARPPPPPPPPAPPRPPPAAPSPPAAPGPRGGGASPGARRSDFLQKTG 140
P ++P R G R P P P P A PP PR A S T
Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 307
Query: 141 SNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSPPGSG--QWKPKVESGDPSL 198
S S G AR + +A P PA L SPP + P S PSL
Sbjct: 308 SPS----------GTKARPVPPPDNAATPL--PAT-LPPSPPLATPLPLAPPSPSAPPSL 354
Query: 199 HPPPSPGTPSATPA-SPPASATPSQRQCVSAAT---------STNDSFEIRPAP---KPV 245
PSP P+ P+ +PP+ TP + S T T+ S + P+P +
Sbjct: 355 QTLPSP--PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSL 412
Query: 246 METIPLGDLQARALASLRANSRNSFMVIPKSKASGAPPPEGRQSVELPKGDLGPASPSQE 305
T LG +A S S S + A P ++ P PASP +
Sbjct: 413 QATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLS--LPASPPLQ 470
Query: 306 LGSQPVPGGDGAPALGKSPLEVEAQWAVEEGACPRTATALADRAIRWQRPSSPPPF-LPA 364
P +P L PL+ + A P ++L + Q +PP P
Sbjct: 471 TSLSPAVSPLSSP-LTIHPLQALSSLASHSPQAP--LSSLIMPPLETQSSLAPPSLQTPP 527
Query: 365 ASEEAEPAEGLRVPGLAKNSREYVRPGLPVTFIDEVDSEEAPQAAKLPYLPHPARPLHPA 424
AS P E L P LA + P+T +++ P L P P P
Sbjct: 528 ASLTTPPLENL--PSLAPPPLQ--TASAPLT-TPHLETPPCPAPCPLQAPPSPLTTPPPE 582
Query: 425 RPGCVAELQPR 435
P +A P+
Sbjct: 583 TPSSIATPPPQ 593
Score = 44.7 bits (104), Expect = 3e-04
Identities = 81/292 (27%), Positives = 100/292 (34%), Gaps = 75/292 (25%)
Query: 43 PGFPPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFD----PPAAPRRRGSPERARPPP 98
P PPA P + + G P S L PP AP +P PP
Sbjct: 786 PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 845
Query: 99 PPPPP---APPRPPPAAPSPPAAPGPR-----GGGASPGARRSDFLQKTG------SNSF 144
PP P AP RPP P + GPR G P RS +G S+S
Sbjct: 846 PPASPTLQAPRRPPTPGPDTSVS-GPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSA 904
Query: 145 TVHPRGLHRGAGARLLSNGHSAPEPRA------------GPANRLA--GSPPGSGQWKPK 190
T P L RG + ++P P A GPA LA G+P W P
Sbjct: 905 TSTPEEL-RGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPA 963
Query: 191 V-----------------ESGDPS---LHPPPSPGTPSATPASPPASATPSQRQCVSAAT 230
ES P+ L P PSPGT S A+ A A S R
Sbjct: 964 TGPGSADGLCTIYETEGPESATPAPGALDPGPSPGT-SGGKAAAGAGAGASSR------- 1015
Query: 231 STNDSFEIRPAPKPV-METIPLGDLQARALASLRANSRNSFMVIPKSKASGA 281
+PK + +PLG LQA + L SR + + A G+
Sbjct: 1016 ----------SPKQARLGELPLGALQASVVQHLL--SRTLLLAAAEGAAGGS 1055
>gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens]
Length = 663
Score = 67.4 bits (163), Expect = 4e-11
Identities = 77/280 (27%), Positives = 101/280 (36%), Gaps = 14/280 (5%)
Query: 45 FPPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPA 104
FP P AP AA AA V A PG S A P P PP P PPP
Sbjct: 111 FPAHPEAPAAAARAAALV----AHPGAGSYPCGGGSSGAQPSAPPPPAPPLPPTPSPPPP 166
Query: 105 PPRPPPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGH 164
PP PPP A S GGG+S DF+ + S T +H +G
Sbjct: 167 PPPPPPPALSGYTTTNSGGGGSSGKGHSRDFVLRR-DLSATAPAAAMHGAPLGGEQRSGT 225
Query: 165 SAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPP--PSPGTPSATPASPPASATPSQ 222
+P+ A P + SG + SG P+L P +PG P P P +
Sbjct: 226 GSPQHPAPPPHSAGMFISASGTYAGPDGSGGPALFPALHDTPGAPGGHP--HPLNGQMRL 283
Query: 223 RQCVSAATSTNDSF-EIRPAPKPVMETIPLGDLQARALASLR---ANSRNSFMVIPKSKA 278
+AA + + + P P G + A A A+L A + N + + A
Sbjct: 284 GLAAAAAAAAAELYGRAEPPFAPRSGDAHYGAVAAAAAAALHGYGAVNLNLNLAAAAAAA 343
Query: 279 SGAPPPEGRQSVELPKGDLGPASPSQELGSQP-VPGGDGA 317
+ P P + P PA P +PG GA
Sbjct: 344 AAGPGPHLQHHAPPPAPPPPPAPAQHPHQHHPHLPGAAGA 383
Score = 45.8 bits (107), Expect = 1e-04
Identities = 28/84 (33%), Positives = 34/84 (40%), Gaps = 16/84 (19%)
Query: 43 PGFPPAPPAPGAAQIR--------AAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERA 94
P PP PPAP + A L Y P + + + DP
Sbjct: 357 PPAPPPPPAPAQHPHQHHPHLPGAAGAFLRYMRQPIKQELICKWIDPDELA--------G 408
Query: 95 RPPPPPPPPAPPRPPPAAPSPPAA 118
PPPPPPPP PP PPPA + P +
Sbjct: 409 LPPPPPPPPPPPPPPPAGGAKPCS 432
Score = 39.7 bits (91), Expect = 0.009
Identities = 101/430 (23%), Positives = 124/430 (28%), Gaps = 114/430 (26%)
Query: 23 RRVPGVRA--LRADSVLIIETVPGFPPAPPAPGAAQIRAAEVLV----YGAPPGRVSRLL 76
R P +R L V ++ + GFP P +Q+RAA + GA PG +
Sbjct: 32 RNPPALRLADLATAQVQPLQNMTGFPALAGPPAHSQLRAAVAHLRLRDLGADPGVATT-- 89
Query: 77 ERFDPPAAPRRRGSPERARPPPPPPP-PAPPRPPPAAPSPPAAPGPRGGGASPGARRSDF 135
P P PP PA P P AA A
Sbjct: 90 -----PLGPEHMAQASTLGLSPPSQAFPAHPEAPAAAARAAA------------------ 126
Query: 136 LQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGD 195
HP GAG+ G S +P A P PP
Sbjct: 127 --------LVAHP-----GAGSYPCGGGSSGAQPSAPP-------PPA------------ 154
Query: 196 PSLHPPPSPGTPSATPASPPAS--ATPSQRQCVSAATSTNDSFEIR-----PAPKPVMET 248
P L P PSP P P P S T + S+ + F +R AP M
Sbjct: 155 PPLPPTPSPPPPPPPPPPPALSGYTTTNSGGGGSSGKGHSRDFVLRRDLSATAPAAAMHG 214
Query: 249 IPLGDLQARALASLRANSRNSFMVIPKSKASGAPPP-------EGRQSVELPKGDLGPAS 301
PLG Q S APPP + P G GPA
Sbjct: 215 APLGGEQRSGTG---------------SPQHPAPPPHSAGMFISASGTYAGPDGSGGPAL 259
Query: 302 PSQELGSQPVPGGDGAPALGKSPLEVEAQWAVEEGACPRTATALADRAIRWQRPSSPPPF 361
+ PGG P G+ L + A A A L RA PPF
Sbjct: 260 FPALHDTPGAPGGHPHPLNGQMRLGLAA-------AAAAAAAELYGRA--------EPPF 304
Query: 362 LPAASEEAEPAEGLRVPGLAKNSREYVRPGLPVTFIDEVDSEEAPQAAKLPYLPHPARPL 421
P + G A Y L + + A A P+L H A P
Sbjct: 305 AP---RSGDAHYGAVAAAAAAALHGYGAVNLNLNL---AAAAAAAAAGPGPHLQHHAPPP 358
Query: 422 HPARPGCVAE 431
P P A+
Sbjct: 359 APPPPPAPAQ 368
Score = 36.6 bits (83), Expect = 0.078
Identities = 34/129 (26%), Positives = 36/129 (27%), Gaps = 46/129 (35%)
Query: 46 PPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSP-----ERARPPPPP 100
PP P G A A A G + L AA P A PP PP
Sbjct: 302 PPFAPRSGDAHYGAVAAAAAAALHGYGAVNLNLNLAAAAAAAAAGPGPHLQHHAPPPAPP 361
Query: 101 PPPAPPR-----------------------------------------PPPAAPSPPAAP 119
PPPAP + PPP P PP P
Sbjct: 362 PPPAPAQHPHQHHPHLPGAAGAFLRYMRQPIKQELICKWIDPDELAGLPPPPPPPPPPPP 421
Query: 120 GPRGGGASP 128
P GGA P
Sbjct: 422 PPPAGGAKP 430
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 66.6 bits (161), Expect = 7e-11
Identities = 90/391 (23%), Positives = 139/391 (35%), Gaps = 68/391 (17%)
Query: 96 PPPPPPPPAPPRPPPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGA 155
PPPPPPPP PP PPP P P+ P G A+P + + T + + H L +
Sbjct: 630 PPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTI--TRLQNASQHSGALFKPP 687
Query: 156 GARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTPSA------ 209
++ + P+ P + PP PPP+PG+ A
Sbjct: 688 TPPVMQSQSVKPQILVPPNGVVPPPPPPP---------------PPPTPGSAMAQLKPAP 732
Query: 210 -TPASPPASATPSQRQCVSAATSTNDSFEIRPAPKPVMETIPLGDLQARALASLRANSRN 268
P+ P SA P + T + P P P+ +P QA + +
Sbjct: 733 CAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLP---PQAPPKPLVTIPAPT 789
Query: 269 SFMVIPKSKASGAPP------PEGRQSVELPKGDLGPASPSQELGSQPVPGGDGAPALGK 322
S + APP P ++ P + P+ P+ + PVP P L K
Sbjct: 790 STKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPV---PVP----PPTLPK 842
Query: 323 SPLEVEAQWAVEEGACPRTATALADRAIRWQRPSSPPPFLPAASEEAEPAEGL------R 376
+ + + P + + I Q P PPP PA E++P + + +
Sbjct: 843 -----QQSFCAKPPPSPLSPVPSVVKQIASQFP--PPPTPPAM--ESQPLKPVPANVAPQ 893
Query: 377 VPGLAKNSREYVRPGLPVTFIDEVDSEEAPQAAKLPYLPHPARPLHPARPGCVAELQPRG 436
P K ++ +PV D P + L + P P P+ PA P P
Sbjct: 894 SPPAVKAKPKWQPSSIPV---PSPDFPPPPPESSLVFPPPPPSPV-PAPP-------PPP 942
Query: 437 SNTFTVVPKR--KPGTLQDQHFSQANREPRP 465
T + P + PG + S ++P P
Sbjct: 943 PPTASPTPDKSGSPGKKTSKTSSPGGKKPPP 973
Score = 55.1 bits (131), Expect = 2e-07
Identities = 84/315 (26%), Positives = 116/315 (36%), Gaps = 73/315 (23%)
Query: 46 PPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGS-----PERAR--PPP 98
PP PPA + ++ V P V + ++ P + P PE + PPP
Sbjct: 872 PPTPPAMESQPLKPVPANVAPQSPPAV-KAKPKWQPSSIPVPSPDFPPPPPESSLVFPPP 930
Query: 99 PP-----PPPAPPRPPPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHR 153
PP PPP P PP A+P+P + SPG + S KT S P R
Sbjct: 931 PPSPVPAPPPPP--PPTASPTPDKS-------GSPGKKTS----KTSSPGGKKPPPTPQR 977
Query: 154 GAGARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPS---LHPPPSPGTPSAT 210
+ + S+G PEP+ + L ++ P ESG PS L PP +P P
Sbjct: 978 NSSIK-SSSGAEHPEPKRPSVDSLV------SKFTPPAESGSPSKETLPPPAAPPKPGKL 1030
Query: 211 PASPPASATPSQRQCVSAATST-----NDSFEIRPA-------PKPVMET-IPLGDLQAR 257
S Q+ CVSA DS P+ P P ET +PL ++
Sbjct: 1031 NLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIP 1090
Query: 258 ALASLRANSRNSFMVI-------PKSKASGAPP---PEGRQSVELPKGDLG--------- 298
A+ S N+ V+ K APP P+ S L + ++
Sbjct: 1091 AVFS--GNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVV 1148
Query: 299 ---PASPSQELGSQP 310
P SP L QP
Sbjct: 1149 PQVPTSPKSSLSVQP 1163
Score = 47.8 bits (112), Expect = 3e-05
Identities = 97/418 (23%), Positives = 139/418 (33%), Gaps = 64/418 (15%)
Query: 43 PGFPPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLER-------FDPPAAPRRRGSPERAR 95
P PP PP P + A ++RL F PP P + + +
Sbjct: 641 PPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQ 700
Query: 96 PPPPPPPPAPPRPPPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGA 155
PP PP PP P PP PG P Q S P +H+
Sbjct: 701 ILVPPNGVVPPPPP---PPPPPTPGSAMAQLKPAPCAPSLPQ----FSAPPPPLKIHQVQ 753
Query: 156 GARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPP 215
++ + P P PA +PP KP V P+ +P A P +P
Sbjct: 754 HITQVA-PPTPPPPPPIPAPLPPQAPP-----KPLVTIPAPTSTKTVAPVVTQAAPPTPT 807
Query: 216 ASATPSQRQCVSAATSTNDSFEIRPAPKPVMETIPLGDLQARALASLRANSRNSFMVIPK 275
P+++Q A+ S P P P T+P Q A + + + K
Sbjct: 808 PPVPPAKKQPAFPASYIPPSPPTPPVPVP-PPTLP---KQQSFCAKPPPSPLSPVPSVVK 863
Query: 276 SKASGAPPPEGRQSVELP-----KGDLGP-------ASPSQELGSQPVPGGDGAPALGKS 323
AS PPP ++E ++ P A P + S PVP D P +S
Sbjct: 864 QIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPES 923
Query: 324 ----PLEVEAQWAVEEGACPRTATALADRA----IRWQRPSSP----PPFLPAASEEAEP 371
P + P TA+ D++ + + SSP PP P + +
Sbjct: 924 SLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKS 983
Query: 372 AEGLRVPGLAKNSREYVRPGLPVTFIDEVDSEEAPQA----AKLPYLPHPARPLHPAR 425
+ G P E RP +D + S+ P A LP PA P P +
Sbjct: 984 SSGAEHP-------EPKRPS-----VDSLVSKFTPPAESGSPSKETLPPPAAPPKPGK 1029
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 66.6 bits (161), Expect = 7e-11
Identities = 54/161 (33%), Positives = 65/161 (40%), Gaps = 36/161 (22%)
Query: 46 PPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPAP 105
P APPA APP L+ AAP+ G PPPPPPPP
Sbjct: 750 PMAPPA--------------SAPP----EFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRA 791
Query: 106 PRPPPAAPSPPAAPGPRGGG-ASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGH 164
P P A+P PP+A G G +SPG + D +T + P G G GA +
Sbjct: 792 PADPAASPDPPSAVASPGSGLSSPGPKPGDSGYETET---PFSPEGAFPGGGA---AEEE 845
Query: 165 SAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPG 205
P PRA P PP G +P + G P P PG
Sbjct: 846 GVPRPRAPP------EPPDPGAPRPPPDPG-----PLPLPG 875
Score = 64.3 bits (155), Expect = 4e-10
Identities = 162/669 (24%), Positives = 213/669 (31%), Gaps = 152/669 (22%)
Query: 95 RPP-PPPPPPAPPRPPPAAPSPPAAPGPRGGGAS---------PGARRSDFLQKTGSNS- 143
RPP PPPPPP P P P PPA PR G S PGA D L T S+
Sbjct: 444 RPPRPPPPPPPPRDGPFPWPWPPAHSAPRPGTLSSPFPLLDGFPGADPDDVLTVTESSRG 503
Query: 144 ------FTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRL--------------AGSPPG 183
+ RG RG GA + P P A P+N A SP
Sbjct: 504 LNLECLWEKARRGAGRGGGAPAWQPASAPPAPHANPSNPFYEALSTPSVLPVISARSPSV 563
Query: 184 SGQWKPKVES-GDP--SLHP----PPSPGTPSATPASPPASATPSQRQCVSAATSTNDSF 236
S ++ ++E G P L P P PG P +P A PS+ + + T + F
Sbjct: 564 SSEYYIRLEEHGSPPEPLFPNDWDPLDPGVP-----APQAPQAPSEVPQLVSETWASPLF 618
Query: 237 EIRPAPKP------------VMETIPLGDLQARALASLRANSRNSFMVIP-----KSKAS 279
PAP+P + P G LA A P + +
Sbjct: 619 ---PAPRPFPAQSSASGSFLLSGWDPEGRGAGETLAGDPAEVLGERGTAPWVEEEEEEEE 675
Query: 280 GAPPPEGRQSVELPKGDLGP-----ASPSQELGSQPVPGGD------GAPALG-KSPLEV 327
G+ P E S+ GP S P+ GD G PALG P E
Sbjct: 676 GSSPGEDSSSLGGGPSRRGPLPCPLCSREGACSCLPLERGDAVAGWGGHPALGCPHPPED 735
Query: 328 EAQWAVEEGAC-----------------PRTATALADRAIRWQRPSSPP-------PFLP 363
++ E G+ P A R P+ PP P P
Sbjct: 736 DSSLRAERGSLADLPMAPPASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRAPADP 795
Query: 364 AASEE-----AEPAEGLRVPGLAKNSREY-----VRPGLPVTFIDEVDSEEAPQAAKLPY 413
AAS + A P GL PG Y P + E P+ P
Sbjct: 796 AASPDPPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGAFPGGGAAEEEGVPRPRAPPE 855
Query: 414 LPHPARPLHPARPGCVAELQPRGSNTFTVVPKRKPGTLQDQHFSQAN---------REPR 464
P P P P PG + PR TF V + + + N RE
Sbjct: 856 PPDPGAPRPPPDPGPLPLPGPREKPTFVVQVSTEQLLMSLREDVTRNLLGEKGATARETG 915
Query: 465 PREAEEEEASCLLGPTLKKRYPTVHEIEVIGGYLALQKSCLTKAGSSRKKMKISFNDKSL 524
PR+A GP +++ P ++ + G G + + N
Sbjct: 916 PRKAGR-------GPGNREKVPGLNRDPTVLG-----------NGKQAPSLSLPVNG--- 954
Query: 525 QTTFEYPSESSLEQEEEVDQQEEEEEEEEEEEEEEEGSGSEEKPFALFLPRATFVSSVRP 584
T E + + EE+ + E EE+ E G + + L S P
Sbjct: 955 VTVLENGDQRAPGIEEKAAENGALGSPEREEKVLENGELTPPRREEKALENGELRS---P 1011
Query: 585 ESSRLPEGSSGLSSYTPKHSVAFSKWQEQALEQAPREAEPPPVEAMVRCGG-----VERW 639
E+ + GL TP S K E + PR E PP R G E W
Sbjct: 1012 EAGEKVLVNGGL---TPPKSE--DKVSENGGLRFPRNTERPPETGPWRAPGPWEKTPESW 1066
Query: 640 GESDTRASP 648
G + T P
Sbjct: 1067 GPAPTIGEP 1075
Score = 49.3 bits (116), Expect = 1e-05
Identities = 102/392 (26%), Positives = 131/392 (33%), Gaps = 79/392 (20%)
Query: 90 SPERARPPPPPPPPAPPRPPPAAPSPPAAPGPRGGG-ASPG----ARRSDFLQKTGSNSF 144
+PE P P PAP AP+P A R GG +PG A ++ L+ G+
Sbjct: 1062 TPESWGPAPTIGEPAPETSLERAPAPSAVVSSRNGGETAPGPLGPAPKNGTLE-PGTERR 1120
Query: 145 TVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSPPGSG-----QWKPKVESGDPSLH 199
G R GA L G P G PGSG W V++ P
Sbjct: 1121 APETGGAPRAPGAGRLDLGSGGRAPVG--TGTAPGGGPGSGVDAKAGW---VDNTRPQPP 1175
Query: 200 PPPSPGTPSATP----ASPPAS----------ATPSQRQCVSAATSTNDSFEIRPAPKPV 245
PPP P P A P +PP + P R A S + PKP
Sbjct: 1176 PPPLPPPPEAQPRRLEPAPPRARPEVAPEGEPGAPDSRAGGDTALSGDGD-----PPKPE 1230
Query: 246 METIPLGDLQARALASLRANSRNSFMVIPK-SKASGAPPPEGRQSVELPKGDLGPASPSQ 304
+ G R L NS + + S+ S A PP P GP P
Sbjct: 1231 RK----GPEMPRLFLDLGPPQGNSEQIKARLSRLSLALPP----LTLTPFPGPGPRRPPW 1282
Query: 305 ELGSQPVPGGDGAPALGKSPLEV------EAQWAVEEGACPRTATALADRAIRWQRPSSP 358
E GG+ A P E E + EE A P A R +
Sbjct: 1283 EGADAGAAGGEAGGAGAPGPAEEDGEDEDEDEEEDEEAAAPGAAAGPRGPG----RARAA 1338
Query: 359 PPFLPAASEEAEPAEGLRVPGLAKNSR--------EYVRPGLPVTF-------------- 396
P + +S +A+ A LR GL K+ R E R V+F
Sbjct: 1339 PVPVVVSSADADAARPLR--GLLKSPRGADEPEDSELERKRKMVSFHGDVTVYLFDQETP 1396
Query: 397 IDEVDSEEAPQAAKLPYL-PHPARPLHPARPG 427
+E+ + P+ P P P P HPA PG
Sbjct: 1397 TNELSVQAPPEGDTDPSTPPAPPTPPHPATPG 1428
Score = 46.6 bits (109), Expect = 8e-05
Identities = 137/609 (22%), Positives = 198/609 (32%), Gaps = 96/609 (15%)
Query: 44 GFPPAPPAPGAAQIRAAEVLVYGAPPGRVS------------------RLLERFDPPAAP 85
G PPAPP P A+ PP V+ F P A
Sbjct: 777 GPPPAPPPPPPPPRAPADPAASPDPPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGAF 836
Query: 86 RRRGSPE-----RARPPPPPPPPAPPRPPPAAPSPPAAPGPRGGGASPGARRSDFLQKTG 140
G+ E R R PP PP P PRPPP P P PGPR + F+ +
Sbjct: 837 PGGGAAEEEGVPRPRAPPEPPDPGAPRPPP-DPGPLPLPGPR--------EKPTFVVQVS 887
Query: 141 SNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHP 200
+ + L LL A GP R AG PG+ + P + + DP++
Sbjct: 888 TEQLLM---SLREDVTRNLLGE-KGATARETGP--RKAGRGPGNREKVPGL-NRDPTVLG 940
Query: 201 PPSPGTPSATPASPPASATPSQRQC--VSAATSTNDSFEIRPAPKPVME----TIPLGDL 254
+ P + ++ + + N + + V+E T P +
Sbjct: 941 NGKQAPSLSLPVNGVTVLENGDQRAPGIEEKAAENGALGSPEREEKVLENGELTPPRREE 1000
Query: 255 QARALASLRANSRNSFMVIPKSKASGAPPPEGRQSVELPKGDLGPASPSQ--ELGSQPVP 312
+A LR+ +++ G PP+ V G P + + E G P
Sbjct: 1001 KALENGELRSPEAGEKVLV----NGGLTPPKSEDKVSENGGLRFPRNTERPPETGPWRAP 1056
Query: 313 G--------GDGAPALGKSPLEVEAQWAVEEGACPRTATALADRAIRWQRPSSPPP---F 361
G AP +G E + ++E P + + P P P
Sbjct: 1057 GPWEKTPESWGPAPTIG----EPAPETSLERAPAPSAVVSSRNGGETAPGPLGPAPKNGT 1112
Query: 362 LPAASEEAEPAEG--LRVPG-----LAKNSREYVRPGL-----PVTFIDE----VDSEEA 405
L +E P G R PG L R V G P + +D VD+
Sbjct: 1113 LEPGTERRAPETGGAPRAPGAGRLDLGSGGRAPVGTGTAPGGGPGSGVDAKAGWVDNTR- 1171
Query: 406 PQAAKLPYLPHP---ARPLHPARPGCVAELQPRGSNTFTVVPKRKPGTLQDQHFSQANRE 462
PQ P P P R L PA P E+ P G P + G D S
Sbjct: 1172 PQPPPPPLPPPPEAQPRRLEPAPPRARPEVAPEGE---PGAPDSRAG--GDTALSGDGDP 1226
Query: 463 PRPREAEEEEASCL--LGPTLKKRYPTVHEIEVIGGYLALQKSCLTK-AGSSRKKMKISF 519
P+P E LGP + + LAL LT G ++
Sbjct: 1227 PKPERKGPEMPRLFLDLGPPQGNSEQIKARLSRLS--LALPPLTLTPFPGPGPRRPPWEG 1284
Query: 520 NDKSLQTTFEYPSESSLEQEEEVDQQEEEEEEEEEEEEEEEGSGSEEKPFALFLPRATFV 579
D + + EE+ + ++E+EEE+EE +G A P V
Sbjct: 1285 ADAGAAGGEAGGAGAPGPAEEDGEDEDEDEEEDEEAAAPGAAAGPRGPGRARAAPVPVVV 1344
Query: 580 SSVRPESSR 588
SS +++R
Sbjct: 1345 SSADADAAR 1353
Score = 45.8 bits (107), Expect = 1e-04
Identities = 97/387 (25%), Positives = 126/387 (32%), Gaps = 66/387 (17%)
Query: 48 APPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPAPP- 106
AP APGA ++ G P + G + RP PPPPP PP
Sbjct: 1127 APRAPGAGRLDLGSG---GRAPVGTGTAPGGGPGSGVDAKAGWVDNTRPQPPPPPLPPPP 1183
Query: 107 --RPPPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGH 164
+P P+PP A PGA S R G LS
Sbjct: 1184 EAQPRRLEPAPPRARPEVAPEGEPGAPDS-------------------RAGGDTALSGDG 1224
Query: 165 SAPEP-RAGP-ANRL---AGSPPG-SGQWKPKVESGDPSLHPPPSPGTPSATPASPP--- 215
P+P R GP RL G P G S Q K ++ +L P P P PP
Sbjct: 1225 DPPKPERKGPEMPRLFLDLGPPQGNSEQIKARLSRLSLALPPLTLTPFPGPGPRRPPWEG 1284
Query: 216 ASATPSQRQCVSAAT----------STNDSFEIRPAPKPVMETIPLGDLQARA------L 259
A A + + A D E A P P G +ARA +
Sbjct: 1285 ADAGAAGGEAGGAGAPGPAEEDGEDEDEDEEEDEEAAAPGAAAGPRGPGRARAAPVPVVV 1344
Query: 260 ASLRANSRNSFMVIPKSKASGAPPPEGRQSVELPK-----GDL-----GPASPSQELGSQ 309
+S A++ + KS GA PE + K GD+ +P+ EL Q
Sbjct: 1345 SSADADAARPLRGLLKS-PRGADEPEDSELERKRKMVSFHGDVTVYLFDQETPTNELSVQ 1403
Query: 310 PVPGGDGAPALGKSPLEVEAQWAVEEGACPRTATALADRAIRWQR--PSSPPPFLPAASE 367
P GD P+ +P A P + + W P PPP P
Sbjct: 1404 APPEGDTDPSTPPAP-PTPPHPATPGDGFPSNDSGFGG-SFEWAEDFPLLPPPGPPLCFS 1461
Query: 368 EAEPAEGLRVPGLAKNSREYVRPGLPV 394
+ L PG + + RP PV
Sbjct: 1462 RFSVSPALETPGPPARAPD-ARPAGPV 1487
Score = 30.4 bits (67), Expect = 5.6
Identities = 32/95 (33%), Positives = 35/95 (36%), Gaps = 27/95 (28%)
Query: 40 ETVPGFPPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPP 99
+T P PPAPP P + A PG + F P GS E A P
Sbjct: 1409 DTDPSTPPAPPTP-----------PHPATPG------DGF-PSNDSGFGGSFEWAEDFPL 1450
Query: 100 PPPPAPP--------RPPPAAPSPPA-APGPRGGG 125
PPP PP P P PPA AP R G
Sbjct: 1451 LPPPGPPLCFSRFSVSPALETPGPPARAPDARPAG 1485
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 65.9 bits (159), Expect = 1e-10
Identities = 123/479 (25%), Positives = 166/479 (34%), Gaps = 89/479 (18%)
Query: 6 ERRRGGGAAGARLLERYRRVPGVRALRADSVLIIETVPGFPPAPPAPGAAQIRAAEVLVY 65
+ +R AGA R PG L+ PG P PP A +R V
Sbjct: 2 DNKRDKAKAGAAARTPAARAPG---------LLTPRPPGSPRPPPPVTPAALR-----VL 47
Query: 66 GAPPGRVSR--LLERFD-------PPAAPRR---RGSPERARPPPPPPPPAP--PRPPPA 111
GA G V R L ER P +APR R + +R P PP + R PPA
Sbjct: 48 GAA-GAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPA 106
Query: 112 ---APSPPAAPGPRGGGASPG-----ARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNG 163
+P P ++PG G PG R + T P+ AGAR ++G
Sbjct: 107 KNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG 166
Query: 164 HS--APEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATPS 221
+ P P +R AG+ G P P++ P T
Sbjct: 167 PTPGTPSPAMARRSRAAGT----------------------EVGLPRPAPSARPRPPTEG 204
Query: 222 QRQCVSAATSTNDSFEIRPAPKPVMETIPLGDLQARALASLRANSRN-SFMVIPKSKASG 280
R+ VS+A+ + + P+P G LQ A SL +++ S A G
Sbjct: 205 PRKSVSSASEHSTT---EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG 261
Query: 281 APPPEGRQSVELPKGDLGPASPSQELGSQPVPGGDGAPALG---KSPLEVEAQWAVEEGA 337
P S PKG L P Q P D APALG SPL + A +
Sbjct: 262 TPRAPAHPSQPKPKG-LQALRPPQ----VTPPRKDAAPALGPLSSSPLATPSPSAALQSQ 316
Query: 338 CPRTATALADRAIRWQRPSSPPPFLPAASEEAEPAEGLRVPGLAKNSREYVRPGLPV--- 394
P T A + + ++P P P + + L P S+ G P
Sbjct: 317 APPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQA 376
Query: 395 --TFIDE-------VDSEEAPQAAKLPYLPHPARPLHPARP--GCVAELQPRGSNTFTV 442
+F+ +AP A LP L P P PA P +A P+ N V
Sbjct: 377 THSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP--PASPPLSPLATPSPQAPNALAV 433
Score = 65.1 bits (157), Expect = 2e-10
Identities = 100/379 (26%), Positives = 132/379 (34%), Gaps = 71/379 (18%)
Query: 82 PAAPRRRGSPERARPPPPPPPPAPPRPPPAAP--SPPAAPGPRGGGASPGARRSDFLQKT 139
PA RR + P P P A PRPP P S +A SP ARR
Sbjct: 174 PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR---PSA 230
Query: 140 GSNSFTVHPRGLHRGAGARLLSNGHSAPEP-RAGPANR-LAGSPPGSGQWKPKVESG--D 195
G GL R A L S+ P R+GP+ R +P Q KPK
Sbjct: 231 GG--------GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP 282
Query: 196 PSLHPPPSPGTPSATPASPPASATPS-----QRQCVSAATSTNDSFEI------------ 238
P + PP P+ P S ATPS Q Q +T S +
Sbjct: 283 PQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAP 342
Query: 239 -RPAPKPVMETIPL-----GDLQARALASLRANSRNSFMVIPKSKASGAPPPEGRQSVEL 292
P+ P ++T+P +L S + +SF+ P PPP+ ++ L
Sbjct: 343 PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALAL 402
Query: 293 PKGDLGPASPSQELGSQPVPGGDGAPALGKSPLEVEAQWAVEEGACPRTATALADRAIRW 352
P P+ P+ S P+ SPL + P+ ALA +
Sbjct: 403 PPLQAPPSPPA----SPPL-----------SPLATPS---------PQAPNALAVHLL-- 436
Query: 353 QRPSSPPPFLPAASEEAEPAEGLRVPGLAKNSR---EYVRPGLPVTFIDEVDSEEAPQAA 409
Q P SPPP P + + PA P S+ P L V +P A
Sbjct: 437 QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 496
Query: 410 KLPYLPHP--ARPLHPARP 426
P P P A PL A+P
Sbjct: 497 PPPQAPPPLAAPPLQLAKP 515
Score = 59.3 bits (142), Expect = 1e-08
Identities = 99/371 (26%), Positives = 129/371 (34%), Gaps = 69/371 (18%)
Query: 26 PGVRALRADSVLIIETVPGFPPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAP 85
P + A S L + P APP+P A PP + + L A
Sbjct: 319 PTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH 378
Query: 86 RRRGSPERA--RPPPPPPPPAPPRPP-PAAPSPPAAPGPRGGGASPGARRSDFLQKTGSN 142
SP + PPP PPA PP A PSPPA+P P A+P + N
Sbjct: 379 SFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASP-PLSPLATPSPQ--------APN 429
Query: 143 SFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKV---ESGDPSLH 199
+ VH LL S P P + SPP S P PSL
Sbjct: 430 ALAVH-----------LLQAPFSPP---PSPPVQAPFSPPASPPVSPSATPPSQAPPSLA 475
Query: 200 PPPSPGTPSATPASPP--ASATPSQRQCVSAATSTNDSFEIRPAPKPVMETIPLGDLQAR 257
PP P + PASPP SATP + A + P P + T PL L +
Sbjct: 476 APPLQ-VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP 534
Query: 258 ALASLRANSRNSFMVIPKSKASGAPPPEGRQSVELPKGDLGPASPS----QELGSQPVPG 313
+ + +P S + PPP+ + P + P+ P+ Q P PG
Sbjct: 535 PASFPGQAPFSPSASLPMSPLA-TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG 593
Query: 314 GDGAPALGKSPLEVEAQWAVEEGACPRTATALADRAIRWQRPSSPPPFLPAASEEAEPAE 373
D + + PR ALA P PPP P+ S P+
Sbjct: 594 PDTSV------------------SGPRLTLALA--------PGPPPP--PSRS----PSS 621
Query: 374 GLRVPGLAKNS 384
L P LA +S
Sbjct: 622 TLSGPDLAGHS 632
Score = 58.2 bits (139), Expect = 3e-08
Identities = 85/337 (25%), Positives = 123/337 (36%), Gaps = 62/337 (18%)
Query: 26 PGVRALRADSVLIIETVPGFPPAPPA------PGAAQIRAAEVLVYGAPPGRVSRLLERF 79
P +A A +V +++ PP+PP P + + + APP + L+
Sbjct: 423 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV- 481
Query: 80 DPPAAPRRRGSPERARPPPPPPPP--APP----RPPPAAPSPPAAPGPRGGGASPGARRS 133
PP+ P A PPP PPP APP +PPP AP P A P SP A
Sbjct: 482 -PPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP-PALATPPLQALPSPPASFP 539
Query: 134 DFLQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVES 193
+ S S + P L + AP A P ++ SPP S
Sbjct: 540 GQAPFSPSASLPMSP----------LATPPPQAPPVLAAPLLQVPPSPPAS--------- 580
Query: 194 GDPSLHPPPSPGTPSATPASPPASATPSQRQCVSAATSTNDSFEIRPAPKPVMETIPLGD 253
P+L P P TP P ++ R ++ A P P P P
Sbjct: 581 --PTLQAPRRPPTPG------PDTSVSGPRLTLALA----------PGPPPPPSRSPSST 622
Query: 254 LQARALASLRANSRNS------FMVIPKSKASGAPPPEGRQSVELPKG-DLGPASPSQEL 306
L LA +++ ++ + P+ A+ +PPP+ + P GPA P
Sbjct: 623 LSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFR 682
Query: 307 GSQPVPGGDGAPALGKSPLEVEAQWAVEEGACPRTAT 343
G+ P PA G P + + E P +AT
Sbjct: 683 GAPGAP-LPWPPATG--PGSADGLCTIYETEGPESAT 716
Score = 56.2 bits (134), Expect = 1e-07
Identities = 91/377 (24%), Positives = 120/377 (31%), Gaps = 58/377 (15%)
Query: 81 PPAAPRRRGSPERARPPPPPPPPAPPRPPPAAPSPPAAPGPRGGGASPGARRSDFLQKTG 140
P ++P R G R P P P P A PP PR A S T
Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 307
Query: 141 SNSFTVHPRGLHRGAGARLLSNGHSA--------------PEPRAGPANRLAGSPPGSGQ 186
S S L A L + HS+ P P A P+ + SPP +
Sbjct: 308 SPS-----AALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPP 362
Query: 187 WKPKVESGDPSLHP-----PPSPGTPSAT--PASPPASATPSQRQCVSAATSTNDSFEIR 239
+ G P+L P P +P AT P +PPA A P + S S S
Sbjct: 363 SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLAT 422
Query: 240 PAPK-PVMETIPLGDLQARALASLRANSRNSFMVIPKSKASGAPPPEGRQSVELPKGDLG 298
P+P+ P + L S + S P S PP + S+ P +
Sbjct: 423 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 482
Query: 299 PASP-SQELGSQPVPGGDGAPALGKSPLEVEAQWAVEEGACPRTATALADRAIRWQRPSS 357
P+ P S + P P L PL++ + P
Sbjct: 483 PSPPASPPMSPSATPPPQAPPPLAAPPLQLA------------------------KPPPQ 518
Query: 358 PPPFLPAASEEAEPAEGLRVPGLAKNSREYVRPGLPVTFIDEVDSEEAPQAAKLPYLPHP 417
PP L +A P+ PG A S P P+ +AP P L P
Sbjct: 519 APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA----TPPPQAPPVLAAPLLQVP 574
Query: 418 ARPLHPARPGCVAELQP 434
P PA P A +P
Sbjct: 575 PSP--PASPTLQAPRRP 589
Score = 45.8 bits (107), Expect = 1e-04
Identities = 83/304 (27%), Positives = 105/304 (34%), Gaps = 75/304 (24%)
Query: 31 LRADSVLIIETVPGFPPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFD----PPAAPR 86
L A + + + P PPA P + + G P S L PP AP
Sbjct: 505 LAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 564
Query: 87 RRGSPERARPPPPPPPP---APPRPPPAAPSPPAAPGPR-----GGGASPGARRSDFLQK 138
+P PP PP P AP RPP P + GPR G P RS
Sbjct: 565 VLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVS-GPRLTLALAPGPPPPPSRSPSSTL 623
Query: 139 TG------SNSFTVHPRGLHRGAGARLLSNGHSAPEPRA------------GPANRLA-- 178
+G S+S T P L RG + ++P P A GPA LA
Sbjct: 624 SGPDLAGHSSSATSTPEEL-RGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFR 682
Query: 179 GSPPGSGQWKPKV-----------------ESGDPS---LHPPPSPGTPSATPASPPASA 218
G+P W P ES P+ L P PSPGT S A+ A A
Sbjct: 683 GAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGT-SGGKAAAGAGA 741
Query: 219 TPSQRQCVSAATSTNDSFEIRPAPKPV-METIPLGDLQARALASLRANSRNSFMVIPKSK 277
S R +PK + +PLG LQA + L SR + +
Sbjct: 742 GASSR-----------------SPKQARLGELPLGALQASVVQHLL--SRTLLLAAAEGA 782
Query: 278 ASGA 281
A G+
Sbjct: 783 AGGS 786
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 65.1 bits (157), Expect = 2e-10
Identities = 89/330 (26%), Positives = 101/330 (30%), Gaps = 66/330 (20%)
Query: 46 PPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPAP 105
PP P P V GA R S PP A G+ R PP P P
Sbjct: 840 PPGPAGPAGPPGPIGNVGAPGAKGARGSA-----GPPGATGFPGAAGRVGPPGPSGNAGP 894
Query: 106 PRPP--------------------PAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFT 145
P PP P PP PGP G SPGA T
Sbjct: 895 PGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGI 954
Query: 146 VHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPP--- 202
RG+ G R P P P + G SG+ P G P L PP
Sbjct: 955 AGQRGVVGLPGQRGERGFPGLPGPSGEPGKQ--GPSGASGERGPPGPMGPPGLAGPPGES 1012
Query: 203 ----------SPG---TPSAT-------PASPP-ASATPSQRQCVSAATSTNDSFEIRPA 241
SPG +P A PA PP A P V A + D E PA
Sbjct: 1013 GREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPA 1072
Query: 242 PKPVMETIPLGDLQARALASLRANSRNSFMVIPK-----------SKASGAPPPEGRQSV 290
P+G + AR A + + + S G P P G
Sbjct: 1073 GPAG----PVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGE 1128
Query: 291 ELPKGDLGPASPSQELGSQPVPGGDGAPAL 320
+ P G GPA P GS PG DG L
Sbjct: 1129 QGPSGASGPAGPRGPPGSAGAPGKDGLNGL 1158
Score = 58.9 bits (141), Expect = 1e-08
Identities = 76/277 (27%), Positives = 97/277 (35%), Gaps = 30/277 (10%)
Query: 47 PAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSP--ERARPPPPPPPPA 104
P PP P A A G P + + AP G+P AR P P P
Sbjct: 373 PGPPGPAGAAGPAGNPGADGQPGAKGAN--------GAPGIAGAPGFPGARGPSGPQGPG 424
Query: 105 PPRPPPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGH 164
P P P APG +G + G +Q + RG G L
Sbjct: 425 GPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPG-- 482
Query: 165 SAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATPSQRQ 224
P R GP +R G P G PK +G+ SPG P+ SP + P +
Sbjct: 483 -PPGERGGPGSR--GFPGADGVAGPKGPAGERG-----SPG-PAGPKGSPGEAGRPGEAG 533
Query: 225 CVSAATSTNDSFEIRPAPKPVMETIPLG----DLQARALASLRANSRNSFMVIPKSK-AS 279
A T +P P +T P G D + A + M P K A+
Sbjct: 534 LPGAKGLTGSP----GSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAA 589
Query: 280 GAPPPEGRQSVELPKGDLGPASPSQELGSQPVPGGDG 316
G P G + V P G +GPA E G+Q PG G
Sbjct: 590 GEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAG 626
Score = 58.5 bits (140), Expect = 2e-08
Identities = 76/283 (26%), Positives = 96/283 (33%), Gaps = 62/283 (21%)
Query: 47 PAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPAPP 106
P PP P + PPG + + +P A G+ A PP P P PP
Sbjct: 805 PGPPGPAG----------FAGPPGADGQPGAKGEPGDA----GAKGDAGPPGPAGPAGPP 850
Query: 107 RPPPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHSA 166
P +P A G RG PGA + F G V P G +G++
Sbjct: 851 GPIGNVGAP-GAKGARGSAGPPGA--TGFPGAAGR----VGPPG----------PSGNAG 893
Query: 167 PEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATPSQRQCV 226
P GPA + G P G+ P +G P PP P P+ SP A
Sbjct: 894 PPGPPGPAGKEGGKGP-RGETGP---AGRPGEVGPPGPPGPAGEKGSPGADG-------- 941
Query: 227 SAATSTNDSFEIRPAPKPVMETIPLGDLQARALASLRAN-SRNSFMVIP-KSKASGAPPP 284
PA P P G R + L F +P S G P
Sbjct: 942 -------------PAGAPGTPG-PQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGP 987
Query: 285 EGRQSVELPKGDLGP---ASPSQELGSQPVPGGDGAPALGKSP 324
G P G +GP A P E G + PG +G+P SP
Sbjct: 988 SGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSP 1030
Score = 56.6 bits (135), Expect = 7e-08
Identities = 98/394 (24%), Positives = 130/394 (32%), Gaps = 58/394 (14%)
Query: 43 PGFP--PAPPAPGAAQIRAAEVLVYG--APPGRVSRLLERFDPPAAPRRRGSPERARPPP 98
PGF P P P + E V G PG P A RG P R
Sbjct: 640 PGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPG----------PSGARGERGFPGE-RGVQ 688
Query: 99 PPPPPAPPRPPPAAPSPPAAPGPRGGGASPGARRSDFLQ----KTGSNSFTVHPRGLHRG 154
PP PA PR AP A G G +PG++ + LQ + G+ P+G
Sbjct: 689 GPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLP-GPKGDRGD 747
Query: 155 A------------GARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPP 202
A G R L+ P P P ++ P SG P G P P
Sbjct: 748 AGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGP--SGPAGPTGARGAPGDRGEP 805
Query: 203 SPGTPSATPASPPASATPSQRQCVSAATSTNDSFEIRPAPKPVMETIPLGDLQARALASL 262
P P+ P A P + A + D+ PA P P+G++ A
Sbjct: 806 GPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPA-GPAGPPGPIGNVGAPGAKGA 864
Query: 263 RANS---------RNSFMVIPKSKAS-----GAPPPEGRQSVELPKGDLGPASPSQELG- 307
R ++ + V P + G P P G++ + P+G+ GPA E+G
Sbjct: 865 RGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGP 924
Query: 308 -SQPVPGGDGAPALGKSPLEVEAQWAVEEGACPRTATALADRAIRWQRPSSPPPF----- 361
P P G+ P + A R L + P P P
Sbjct: 925 PGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGK 984
Query: 362 --LPAASEEAEPAEGLRVPGLAKNSREYVRPGLP 393
AS E P + PGLA E R G P
Sbjct: 985 QGPSGASGERGPPGPMGPPGLAGPPGESGREGAP 1018
Score = 50.1 bits (118), Expect = 7e-06
Identities = 63/260 (24%), Positives = 76/260 (29%), Gaps = 56/260 (21%)
Query: 81 PPAAPRRRGSPERARPPPPPPPPAPPRPPP---------------------AAPSPPAAP 119
P P R G P + P PP PP PP PP + P P
Sbjct: 125 PAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPS 184
Query: 120 GPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAG 179
GPRG PGA G F +G G S P GP G
Sbjct: 185 GPRGLPGPPGA--------PGPQGF--------QGPPGEPGEPGASGPMGPRGP----PG 224
Query: 180 SPPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATPSQRQCVSAATSTNDSFEIR 239
P +G + G P PP P P + R + D+
Sbjct: 225 PPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAG 284
Query: 240 PAPKPVM--ETIPLGDLQARALASLRANSRNSFMVIPKSKASGAPPPEGRQSVELPKGDL 297
P +P E G + R L R GAP P G + + G
Sbjct: 285 PKGEPGSPGENGAPGQMGPRGLPGERGR-------------PGAPGPAGARGNDGATGAA 331
Query: 298 GPASPSQELGSQPVPGGDGA 317
GP P+ G PG GA
Sbjct: 332 GPPGPTGPAGPPGFPGAVGA 351
Score = 48.1 bits (113), Expect = 3e-05
Identities = 65/277 (23%), Positives = 79/277 (28%), Gaps = 11/277 (3%)
Query: 43 PGFPPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPP 102
P PP PP P A L YG + P P PP P
Sbjct: 143 PPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGI-----SVPGPMGPSGPRGLPGPPGAPG 197
Query: 103 PAPPRPPPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSN 162
P + PP P P A GP G PG + RG GAR L
Sbjct: 198 PQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPG 257
Query: 163 GHSAPEPRAGPA-NRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATPS 221
P + + L G+ +G PK E G P + P P P P
Sbjct: 258 TAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPG 317
Query: 222 QRQCVSAATSTNDSFEIRPAPKPVMETIPLGDLQARALASLRANSRNSFMVIPKSKASGA 281
+ A + + P P P G A A + G
Sbjct: 318 P----AGARGNDGATGAAGPPGPTGPAGPPG-FPGAVGAKGEAGPQGPRGSEGPQGVRGE 372
Query: 282 PPPEGRQSVELPKGDLGPASPSQELGSQPVPGGDGAP 318
P P G P G+ G G+ PG GAP
Sbjct: 373 PGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAP 409
Score = 47.0 bits (110), Expect = 6e-05
Identities = 63/233 (27%), Positives = 73/233 (31%), Gaps = 52/233 (22%)
Query: 91 PERARPPPPPPPPAPPRPPPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRG 150
P+ P P PA P P P PGP G PG P G
Sbjct: 113 PKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPG------------------PPG 154
Query: 151 LHRGAGARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGT---- 206
L G+ AP+ G + G G P G P PP +PG
Sbjct: 155 L----------GGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPG--PPGAPGPQGFQ 202
Query: 207 -PSATPASPPASATPSQRQCVSAATSTNDSFEIRPAPKPVMETIPLGDLQARALASLRAN 265
P P P AS R D E +P E P G AR L
Sbjct: 203 GPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRP-GERGPPGPQGARGLPGTAG- 260
Query: 266 SRNSFMVIPKSKASGAPPPEGRQSVELPKGDLGPASPSQELGSQPVPGGDGAP 318
+P K G ++ KGD GPA P E GS PG +GAP
Sbjct: 261 -------LPGMKGH-----RGFSGLDGAKGDAGPAGPKGEPGS---PGENGAP 298
Score = 44.7 bits (104), Expect = 3e-04
Identities = 57/204 (27%), Positives = 64/204 (31%), Gaps = 38/204 (18%)
Query: 46 PPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPAP 105
PP P P E GAP S R P A RG A PP P P
Sbjct: 996 PPGPMGPPGLAGPPGESGREGAPGAEGSP--GRDGSPGAKGDRGETGPAGPPGAPGAPGA 1053
Query: 106 PRPP-------------PAAPSPPAAPGPRGGGASPGARRSDFLQ--KTGSNSFTVHPRG 150
P P PA P+ P P G A P R D + + G H RG
Sbjct: 1054 PGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGH-RG 1112
Query: 151 LH--RGAGARLLSNGHSAPEPRAGPANRLAGSPPGS----------------GQWKPKVE 192
+G S G P +GPA PPGS G P+
Sbjct: 1113 FSGLQGPPGPPGSPGEQGPSGASGPAG--PRGPPGSAGAPGKDGLNGLPGPIGPPGPRGR 1170
Query: 193 SGDPSLHPPPSPGTPSATPASPPA 216
+GD PP P P P P A
Sbjct: 1171 TGDAGPVGPPGPPGPPGPPGPPSA 1194
Score = 39.3 bits (90), Expect = 0.012
Identities = 30/95 (31%), Positives = 33/95 (34%), Gaps = 16/95 (16%)
Query: 46 PPAPPAPGAAQIRAAEVLVYG--APPGR--------VSRLLERFDPPAAPRRRGSPERAR 95
PP PP Q + G PPG ++ L PP R G
Sbjct: 1119 PPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVG 1178
Query: 96 PPPPPPPPAPPRPPPAA------PSPPAAPGPRGG 124
PP PP PP PP PP A P PP GG
Sbjct: 1179 PPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGG 1213
Score = 30.8 bits (68), Expect = 4.3
Identities = 17/40 (42%), Positives = 19/40 (47%), Gaps = 3/40 (7%)
Query: 279 SGAPPPEGRQSVELPKGDLGPASPSQELGSQPVPGGDGAP 318
S +P + VE PKGD GP P G PG DG P
Sbjct: 99 SESPTDQETTGVEGPKGDTGPRGPRGPAGP---PGRDGIP 135
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 65.1 bits (157), Expect = 2e-10
Identities = 57/204 (27%), Positives = 74/204 (36%), Gaps = 37/204 (18%)
Query: 43 PGFPPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPP----- 97
PG P PP G + + PPG+ + D +PR + PP
Sbjct: 115 PGKPQGPPPQGGNRPQGPP------PPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQ 168
Query: 98 ---PPPPPPAPPRPPPAAPSPPAAPGPRGG--GASPGARRSDFLQKTGSNSFTVHPRGLH 152
PPPPP P PPP P P P G G P +S Q P+G +
Sbjct: 169 PQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGN 228
Query: 153 RGAGARLLSNGHSAPEPRAG---------------PA-----NRLAGSPPGSGQWKPKVE 192
+ G P P+ G PA ++ A SPPG Q P+ E
Sbjct: 229 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQE 288
Query: 193 SGDPSLHPPPSPGTPSATPASPPA 216
+P PPP+ G P P +PPA
Sbjct: 289 GNNPQGPPPPAGGNPQ-QPQAPPA 311
Score = 61.6 bits (148), Expect = 2e-09
Identities = 78/310 (25%), Positives = 96/310 (30%), Gaps = 62/310 (20%)
Query: 68 PPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPAPP------RPPPAAPSPPAAPGP 121
PPG+ P P +G + PPPP P PP R P + P P P P
Sbjct: 53 PPGK----------PQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPP 102
Query: 122 RGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSP 181
+GG G P+G +R G G P G +R SP
Sbjct: 103 QGGNQPQGP------PPPPGKPQGPPPQGGNRPQGPP--PPGKPQGPPPQGDKSRSPRSP 154
Query: 182 PGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATPSQRQCVSAATSTNDSFEIRPA 241
PG Q P + G+ PPP PG P P P P + P
Sbjct: 155 PGKPQGPPP-QGGNQPQGPPPPPGKPQGPP--PQGGKKP----------------QGPPP 195
Query: 242 PKPVMETIPLGDLQARALASLRANSRNSFMVIPKSKASGAPPPEGRQSVELPKGDLGPAS 301
P P GD SR+S P K G PP G Q P P
Sbjct: 196 PGKPQGPPPQGD-----------KSRSS--QSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 242
Query: 302 PSQELGSQPVPGGDGAPALGKSPLEVEAQWAVEEGACPRTATALADRAIRWQRPSSPPPF 361
P + G++P G P GK + + A P PPP
Sbjct: 243 PPPQGGNKP----QGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPP- 297
Query: 362 LPAASEEAEP 371
PA +P
Sbjct: 298 -PAGGNPQQP 306
Score = 58.5 bits (140), Expect = 2e-08
Identities = 46/167 (27%), Positives = 58/167 (34%), Gaps = 27/167 (16%)
Query: 46 PPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPAP 105
P PP PG Q PP + + PP P+ +P PPPPP
Sbjct: 190 PQGPPPPGKPQ----------GPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGK 239
Query: 106 PR-PPPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGH 164
P+ PPP + P P P G P A+ Q S P G +G + +N
Sbjct: 240 PQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARS------PPGKPQGPPQQEGNNPQ 293
Query: 165 SAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTPSATP 211
P P G + P G Q P+ PP G PS P
Sbjct: 294 GPPPPAGGNPQQPQAPPAGQPQGPPR----------PPQGGRPSRPP 330
Score = 38.5 bits (88), Expect = 0.021
Identities = 66/307 (21%), Positives = 89/307 (28%), Gaps = 50/307 (16%)
Query: 159 LLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPP--------------SP 204
L++ P P+ G + PPG Q P P PPP SP
Sbjct: 31 LIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSP 90
Query: 205 GTPSATPASPPASA-------TPSQRQCVSAATSTNDSFEIRPAPKPVMETIPLGDLQAR 257
+P P PP P + + + P P P GD
Sbjct: 91 RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGD---- 146
Query: 258 ALASLRANSRNSFMVIPKSKASGAPPPEGRQSVELPKGDLGPASPSQELGSQ----PVPG 313
++ S S P K G PP G Q P P P + G + P PG
Sbjct: 147 -----KSRSPRS----PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPG 197
Query: 314 -GDGAPALGKSPLEVEAQWAVEEGACPRTATALADRAIRWQRPSSPPP---FLPAASEEA 369
G P G ++ +G P+ +P PPP P
Sbjct: 198 KPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 257
Query: 370 EPAEGLRVPGLAKNSREYVRPGLPVTFIDEVDSEEAPQAAKLPYLPHPARPLHPARPGCV 429
+G G +K+ PG P Q P P P +P +P
Sbjct: 258 GKPQGPPAQGGSKSQSARSPPGKP--------QGPPQQEGNNPQGPPPPAGGNPQQPQAP 309
Query: 430 AELQPRG 436
QP+G
Sbjct: 310 PAGQPQG 316
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 64.7 bits (156), Expect = 3e-10
Identities = 145/654 (22%), Positives = 217/654 (33%), Gaps = 155/654 (23%)
Query: 58 RAAEV-LVYGAPPGRVSRLL-ERFDPPAAPRRRGS--------PERARPPPPPPPPAPPR 107
RAAE +V PP +S E P RRRG P PPPP PPP PP
Sbjct: 199 RAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPP 258
Query: 108 PPPAAP------SPP--------------AAPGPRGGGASPGARRSD-----FLQKTGSN 142
PPP P SPP A GP G++P R+ +
Sbjct: 259 PPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAP 318
Query: 143 SFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANR----LAGSPPGSGQWKPKVESG--DP 196
++T HP G RL+ P PR A A PPGS + +V+ D
Sbjct: 319 AYTAHP------PGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDS 372
Query: 197 SLHPPPSPGTPSATPASPPASATPSQRQCVSAATSTNDSFE-IRPAP---------KPVM 246
S+ P + P+ PP P S+++S+N + P P P +
Sbjct: 373 SVSPAATTACVPYAPSRPP--GLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPAL 430
Query: 247 ETIPLGDLQARALAS----LRANSRNSFMVIPKSKASGAPPP------------------ 284
E G L A +S L A + + +P +S PPP
Sbjct: 431 EVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPA 490
Query: 285 ------EGRQSVELPKGDLGPASPSQELGSQPVPGGDG--APALGKSPLEVEAQWAVEEG 336
+G EL G GP P+ P+P +G P + + +
Sbjct: 491 CRAAREDGEILEELFFGTEGPPRPA----PPPLPHREGFLGPPASRFSVGTQDSHTPPTP 546
Query: 337 ACPRTATALADRAIRWQRPSSPPPFLPAASEEAEPAEGLRVPGLAKNSREYVRPGLPVTF 396
P T+++ ++ P+ P F P P LA++ RP P
Sbjct: 547 PTPTTSSSNSNSGSHSSSPAGPVSFPPP-------------PYLARSIDPLPRPPSPAQ- 592
Query: 397 IDEVDSEEAPQAAKLPYLPHPARPLHPARPGCVAELQ-PRGSNTFTVVPKRKPGTLQDQH 455
+ D P LP P P H G + PR +F P+ PG
Sbjct: 593 -NPQDPPLVPLTLALP--PAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPG------ 643
Query: 456 FSQANREPRPREAEEEEASCLLGPTLKKRYPTVHEIEVIGGYLALQKSCLTKAGSSRKKM 515
P P GP K P + + +R
Sbjct: 644 -------PPP------------GPLSKAPQPVPPGVGEL---------------PARGPR 669
Query: 516 KISFNDKSLQTTFEYPSESSLEQE--EEVDQQEEEEEEEEEEEEEEEGSGSEEKPFALFL 573
F L+ FE P+E + + + + +E +EEE+++ E + + P L
Sbjct: 670 LFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPP--LKE 727
Query: 574 PRATFVSSVRPESSRLPEGSSGLSSYTPKHSVAFSKWQEQALEQAPREAEPPPV 627
P A+ S +++ + + T + + QE+ + P PPP+
Sbjct: 728 PFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPL 781
Score = 53.1 bits (126), Expect = 8e-07
Identities = 45/159 (28%), Positives = 63/159 (39%), Gaps = 41/159 (25%)
Query: 92 ERARPPP--PPPPPAPPRPPPAAPSPPAAPGP--------------------RGGGASPG 129
E +PPP PPPPP PPP+ P PP P P RG GA+
Sbjct: 767 EEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVS 826
Query: 130 ARRSDFLQKTGSNSFTVHPRGLHRGAGA----RLLSNGHSAPEPRAGPANRLAGSPPGSG 185
R G T + G GA A + +P+P A +++ + S G
Sbjct: 827 TR-------PGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTS---GG 876
Query: 186 QWKPKVESGDPSLHPPPSPGTPSATPASPPASATPSQRQ 224
W + +G+ P P P TP+ P PP S P++ +
Sbjct: 877 PWARERRAGE---EPVPGPMTPTQPP--PPLSLPPARSE 910
Score = 43.5 bits (101), Expect = 6e-04
Identities = 99/421 (23%), Positives = 127/421 (30%), Gaps = 128/421 (30%)
Query: 100 PPPPAPPRPPPAAPSPPAA-PGPRG-GGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGA 157
PP PP P PPAA GP G G SPG +R
Sbjct: 195 PPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKR------------------------- 229
Query: 158 RLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPAS 217
R G + G PPG + P L PPP P P P A+
Sbjct: 230 ------------RRGCNSEQTGLPPG-------LPLPPPPLPPPPPPPPPPPPPLPGLAT 270
Query: 218 ATPSQRQCVSAATSTNDSFEIRPAPKPVMETIPLGDLQARALASLRANSRNSFMVIPKSK 277
+ P Q KP + + GD P+ K
Sbjct: 271 SPPFQ------------------LTKPGLWSTLHGDAWG-----------------PERK 295
Query: 278 ASGAPP--PEGRQSVELPKGDLGPASPSQELGSQPVPGGDGAPALGKSPLEVEAQWAVEE 335
S APP E R S+ P PA + G + VP P G P E+
Sbjct: 296 GS-APPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGP--GPRPPGAES-----H 347
Query: 336 GACPRTATALAD-RAIRWQRPSSPPPFLPAASEEAEPAEGLRVPGL---------AKNSR 385
G P T +D R R QR PAA+ P R PGL + +S
Sbjct: 348 GCLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSN 407
Query: 386 EYVR-----PGLPVTFIDEVDSEEAPQAAKL------------------PYLPHPARPLH 422
+R PG+P + + E +L P+L P P
Sbjct: 408 TGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSS 467
Query: 423 PARPGCVAELQPRGSNTFTVVP----KRKPGTLQDQHFSQANREPRPREAEEEEASCLLG 478
P P C L+P + P R+ G + ++ F PRP LG
Sbjct: 468 PPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLG 527
Query: 479 P 479
P
Sbjct: 528 P 528
Score = 42.4 bits (98), Expect = 0.001
Identities = 86/355 (24%), Positives = 116/355 (32%), Gaps = 52/355 (14%)
Query: 47 PAPPAPGA-AQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPAP 105
P PP+P Q L PP PP++ + S RP P P +
Sbjct: 585 PRPPSPAQNPQDPPLVPLTLALPPA----------PPSSCHQNTSGSFRRPESPRPRVSF 634
Query: 106 PRPPPAAPSPPAA-------PGPRGGGASP--GARRSDFL------QKTGSNSFTVHPRG 150
P+ P P PP P P G G P G R DF Q F + P G
Sbjct: 635 PKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDG 694
Query: 151 LHRGAGARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTPSAT 210
L A ++ + AG P +P ++ SL P T T
Sbjct: 695 L-----ANIMKMLDESIRKEEEQQQHEAGVAP-----QPPLKEPFASLQSPFPTDTAPTT 744
Query: 211 PASPPASATPSQRQCVSAATSTNDSF--EIRPAPKPVMETIPLGDLQ-----ARALASLR 263
A A T + + AT + P P P+ + P Q + ASL
Sbjct: 745 TAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASL- 803
Query: 264 ANSRNSFMVIPKSKASGAPPPEGRQSVELPKGDLGPASPSQELGSQPVPGGDGAPALGKS 323
S S + K G + LP P PS G+ +P AP+ S
Sbjct: 804 LKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPS---GATALPPTSAAPSAQGS 860
Query: 324 P---LEVEAQWAVEEGACPRTATALADRAIRWQRPSSPPP--FLPAASEEAEPAE 373
P +Q++ G R A + P+ PPP LP A E+E E
Sbjct: 861 PQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLE 915
Score = 38.5 bits (88), Expect = 0.021
Identities = 21/54 (38%), Positives = 29/54 (53%), Gaps = 6/54 (11%)
Query: 89 GSPERARPPPPPPPPAPPRPPPAAPSPPAA--PGPRG---GGASPGARRSDFLQ 137
G +A+PP P PP+ P P A P+PP+A PG + PG R+D L+
Sbjct: 1039 GGASKAKPPTAPAPPSAP-APSAQPTPPSASVPGKKAREEAPGPPGVSRADMLK 1091
Score = 33.1 bits (74), Expect = 0.86
Identities = 149/653 (22%), Positives = 202/653 (30%), Gaps = 114/653 (17%)
Query: 24 RVPGVRALRADSVLIIETVPGFPPAPPAPGAAQ------------IRAA-------EVLV 64
R P + A A L + P PP PP P + RAA E L
Sbjct: 446 RKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELF 505
Query: 65 YG-------APPGRVSRLLERF-DPPAAPRRRGSPERARPPPPPPP-------------- 102
+G APP R E F PPA+ G+ + PP PP P
Sbjct: 506 FGTEGPPRPAPPPLPHR--EGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSS 563
Query: 103 --------PAP----------PRPPPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSF 144
P P PRPP A +P P A P A S Q T S SF
Sbjct: 564 SPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNT-SGSF 622
Query: 145 TVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGS-PPGSGQWKPKVESGDPSLHPPPS 203
R + + G P P GP ++ PPG G+ + G PP+
Sbjct: 623 RRPESPRPRVSFPKTPEVG---PGPPPGPLSKAPQPVPPGVGELPAR---GPRLFDFPPT 676
Query: 204 P-----GTPSATPASPPASATPSQRQCVS-AATSTNDSFEIRPAPKPVMETIPLGDLQAR 257
P P+ P A + S E AP+P ++ P LQ+
Sbjct: 677 PLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKE-PFASLQSP 735
Query: 258 ALASLRANSRNSFMVIPKSKASGAPPPEGRQSVELPKGDLGPASPSQEL--GSQPVPGGD 315
+ + + + + ++ + P L P P + SQP P
Sbjct: 736 FPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPP 795
Query: 316 GAP---ALGKSPLEV-EAQWAVEEGACPRTATALADRAIRWQRPSSP------PPFLPAA 365
P +L KS V E Q G +T P P PP A
Sbjct: 796 PPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAP 855
Query: 366 SEEAEPAEGLRVPGLAKNSREYVRPGLPVTFIDEVDSEEAPQAAKLPYLPHPARPLHPAR 425
S + P A +S ++ G P E P P P P L PAR
Sbjct: 856 SAQGSPQPS------ASSSSQFSTSGGPWARERRAGEEPVP-GPMTPTQPPPPLSLPPAR 908
Query: 426 PGC-VAELQPRGSNTF------TVVPKRKPGTLQDQHFSQANREPRPREAEEEEASCLLG 478
V E R T + P + S R P +A+EE
Sbjct: 909 SESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEAGGVAAV 968
Query: 479 PTLKKRYPTVHEIEVIGGYLALQKSCLTKAGSSRKKMKISFNDKSLQTTFEYPSESSLEQ 538
KR H+ E A + S + R K K + P E S
Sbjct: 969 SGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKA-----------KVPKEKSRRV 1017
Query: 539 EEEVDQQEEEEEEEEEEEEEEEGSGSEEKPFALFLPRATFVSS-VRPESSRLP 590
+D Q EE + E+ + G+ + P A P A S+ P S+ +P
Sbjct: 1018 LGNLDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVP 1070
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 63.5 bits (153), Expect = 6e-10
Identities = 81/277 (29%), Positives = 101/277 (36%), Gaps = 26/277 (9%)
Query: 46 PPAPPAPGAAQIRAAEV--------LVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPP 97
PP PPAP + A+ V P S E PAA + + +PP
Sbjct: 771 PPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPP 830
Query: 98 -PPPPPPAPPRPPPAAPSPP-----AAPGPRGGGASPGARRSDFLQK--TGSNSFTVHPR 149
P PPPAPP P PA+ +P P G G R D T S V R
Sbjct: 831 GSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLR 890
Query: 150 GLHRGAGARLLSNGHSAPEP--RAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTP 207
+ GA + G SAP+ R + R + P S V SL S G
Sbjct: 891 SVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSL--AASEGLS 948
Query: 208 SATPASPP-ASATPSQRQCVSAATSTNDSFEIRPAPKPVMETIPLGDLQARALASLRANS 266
SA P PP A P Q +A+ + +PV DLQ +A LR+ S
Sbjct: 949 SAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQ-ADLQRNLVAELRSIS 1007
Query: 267 RNSFMVIPKSKASGAPPPEGRQSVELPKGDLGPASPS 303
PK PP + SV +P PASPS
Sbjct: 1008 EQRPPQAPKKSPKAPPPVARKPSVGVPP----PASPS 1040
Score = 61.2 bits (147), Expect = 3e-09
Identities = 82/319 (25%), Positives = 110/319 (34%), Gaps = 36/319 (11%)
Query: 66 GAPPGRVSRLLERFDPPAAPRRRGS-PERARPPPPPPPPAPPRPP----PAAPSPPAAPG 120
G GR L + PP PRR S +R P P PP+P P P PP G
Sbjct: 482 GQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGG 541
Query: 121 PRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAG-------- 172
G GA+P +NS+ GL G R + P +G
Sbjct: 542 SEGAGAAP-------CPPNPANSWV---PGLSPGGSRRPPRSPERTLSPSSGYSSQSGTP 591
Query: 173 --PANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTPSATP-ASPPASATPSQRQCVSAA 229
P LAG P G+ +P SL P + + S T S + PS R
Sbjct: 592 TLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQIL 651
Query: 230 TSTNDSFEIRPAPKPVMETIPLGDLQARALASLRANSRNSFMVIPKSKASGAPPPEGRQS 289
T D F I P PK P + A + + + P S +P QS
Sbjct: 652 TPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASP-----QS 706
Query: 290 VELPKGDLGPASPSQELGSQPVPGGDGAPALGKSPLEVEAQWAVEEGACPRTATALADRA 349
P+ L P S + P P+ P + V E +A+ A+
Sbjct: 707 PPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAP---SASETAEEP 763
Query: 350 IRWQRPSSPPPFLPAASEE 368
+ Q P+ PPP PA E+
Sbjct: 764 L--QDPNWPPPPPPAPEEQ 780
Score = 58.5 bits (140), Expect = 2e-08
Identities = 123/473 (26%), Positives = 160/473 (33%), Gaps = 71/473 (15%)
Query: 44 GFPPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSP------ERARPP 97
G P PP P A V G PG R PP +P R SP + P
Sbjct: 546 GAAPCPPNP-------ANSWVPGLSPGGSRR------PPRSPERTLSPSSGYSSQSGTPT 592
Query: 98 PPPPPPAPPRPPPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGA 157
PP A P P PP P SPGA S L S+S P
Sbjct: 593 LPPKGLAGPPASPGKAQPP-KPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQIL 651
Query: 158 RLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPP-SPGTPSATPASPPA 216
L + P PA SPP S P + P+L P PG S T ASP +
Sbjct: 652 TPLGDRFVIPPHPKVPA---PFSPPPSKPRSPNPAA--PALAAPAVVPGPVSTTDASPQS 706
Query: 217 SATPSQRQCVSAATSTNDSFEIRPAPKPVMETIPLGDLQARALASLRANSRNSFMVIPKS 276
TP Q S S + P P P P + + A S + P
Sbjct: 707 PPTP-QTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQ 765
Query: 277 KAS-GAPPPEGRQSVELPKGDLGPASPSQELGSQPVPGG-DGAPALGKSPLEVEAQWAVE 334
+ PPP + +L D P + + P P G G+P L SP
Sbjct: 766 DPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSP---------- 815
Query: 335 EGACPRTATALADRAIRWQRPSSP-PPFLPAASEEAEPAEG--LRVP-----GLAKNS-- 384
A++ + A++ Q P SP PP P A A A G ++P G +K
Sbjct: 816 ------AASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGP 869
Query: 385 -REYVRPGLPVTF-----IDEVDSEEAPQAAKLPYL--PHPARPLHPARPGCVAELQPRG 436
RE V G P+ + + S AP A P L P +PL A G + +
Sbjct: 870 PREDV--GAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPS 927
Query: 437 SNTFTVVPKRKPGTLQDQHFSQA------NREPRPREAEEEEASCLLGPTLKK 483
S V + + S A EPRP ++ AS + +K
Sbjct: 928 SGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRK 980
Score = 51.2 bits (121), Expect = 3e-06
Identities = 132/527 (25%), Positives = 179/527 (33%), Gaps = 115/527 (21%)
Query: 43 PGFPP----APPA-PGAAQIRAAE-VLVYGAPPGRVSRLLERF-----DPPAAPRRRGSP 91
P PP PPA PG AQ E V +P VS L DP AP R P
Sbjct: 591 PTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDP--APSDRSGP 648
Query: 92 ERARP-------PPPPPPPAPPRPPPAAP-SP-PAAPGPRGGGASPG--ARRSDFLQKTG 140
+ P PP P PAP PPP+ P SP PAAP PG + Q
Sbjct: 649 QILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPP 708
Query: 141 SNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLH- 199
+ T+ P + ++S S P P+ + PP KP+V PS
Sbjct: 709 TPQTTLTPL-----QESPVISKDQSPP-----PSPPPSYHPPPPPTKKPEVVVEAPSASE 758
Query: 200 -----------PPPSPGTPS-------------------ATPASPPASATPSQRQCVSAA 229
PPP P P A+P S +P +A+
Sbjct: 759 TAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAAS 818
Query: 230 TSTNDSFEIRPAPKPVMETIPLGDLQARALASLRANSRNSFMVIPKSKASGAPPPEGRQS 289
+S+ + +I+P P P A +S + P + G PP R+
Sbjct: 819 SSSATALQIQPPGSPDPPPAPPAPAPA---SSAPGHVAKLPQKEPVGCSKGGGPP--RED 873
Query: 290 VELPKGDLGPASPS----QELGSQPVPGGDGAPALGKSPLEVEAQWAVEEGACP------ 339
V P +PS L S PGG PALG S + + A+ A P
Sbjct: 874 VGAPL-----VTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSS 928
Query: 340 --------RTATALADRAIRWQRPSSPPPFLPAASEE-AEPAEGLRVPGLAKNSREYVRP 390
+ + A + +P+ PP P + A A + G K E RP
Sbjct: 929 GLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLE--RP 986
Query: 391 GLPVTFID----------EVDSEEAPQAAKLPYLPHPARPLHPARPGCVAELQPRGSNTF 440
P T D + + PQA K P P AR V + P S ++
Sbjct: 987 VSPETQADLQRNLVAELRSISEQRPPQAPK----KSPKAPPPVARKPSVG-VPPPASPSY 1041
Query: 441 TVVPKRKPGTLQDQHFSQANREPRPRE-AEEEEASCLLGPTLKKRYP 486
P+ +P T + ++ RE AE L+GP K P
Sbjct: 1042 ---PRAEPLTAPPTNGLPHTQDRTKRELAENGGVLQLVGPEEKMGLP 1085
Score = 29.6 bits (65), Expect = 9.6
Identities = 37/123 (30%), Positives = 42/123 (34%), Gaps = 14/123 (11%)
Query: 101 PPPAPPRPPPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLL 160
PP AP P P P GAS G RR + S+ R + AGA
Sbjct: 6 PPAAPAAEEPGNPGGPPRRKKSRSGAS-GLRR--------AFSWLRGKRRKKKAAGA--- 53
Query: 161 SNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATP 220
G PRA A A G G+ K E+ D L P G SA P
Sbjct: 54 -EGAEPAAPRAKKAEDKAKRAKGKGRGSAKAEN-DKHLSVGPGQGPGSAVDEHQDNVFFP 111
Query: 221 SQR 223
S R
Sbjct: 112 SGR 114
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 63.5 bits (153), Expect = 6e-10
Identities = 67/265 (25%), Positives = 93/265 (35%), Gaps = 46/265 (17%)
Query: 43 PGFPPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPP 102
PG P PP G Q + PP R + P P + G+ + PP P P
Sbjct: 75 PGKPEGPPPQGGNQSQG--------PPPRPGK------PEGQPPQGGNQSQGPPPRPGKP 120
Query: 103 PAPP-------RPPPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGA 155
PP + PP P P P P+GG S G + G P+G ++
Sbjct: 121 EGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPP-----PRPGKPEGPP-PQGGNQSQ 174
Query: 156 GARLLSNGHSAPEPRAGPANRLAGSPPGSGQWK-PKVESGDPSLHPPPSPGTPSATPA-- 212
G P P+ G N+ G PP G+ + P + G+ S PPP PG P P+
Sbjct: 175 GPPPHPGKPEGPPPQGG--NQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQG 232
Query: 213 -SPPASATPSQRQCVSAATSTNDSFEIRPAPKPVMETIPLGDLQARALASLRANSRNSFM 271
+ P P + + + P P P G + L
Sbjct: 233 GNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPP---------- 282
Query: 272 VIPKSKASG-APPPEGRQSVELPKG 295
P K G PPP+G + P+G
Sbjct: 283 --PAGKPQGPPPPPQGGRPHRPPQG 305
Score = 59.3 bits (142), Expect = 1e-08
Identities = 76/279 (27%), Positives = 91/279 (32%), Gaps = 45/279 (16%)
Query: 63 LVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPP--------PPPPPPAPPRPPP---- 110
++ G P GR R P P G PE RPP PPP P P PPP
Sbjct: 31 VISGKPEGR--RPQGGNQPQRTPPPPGKPE-GRPPQGGNQSQGPPPRPGKPEGPPPQGGN 87
Query: 111 AAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPR 170
+ PP PG G G +S P+G ++ G P P+
Sbjct: 88 QSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQ 147
Query: 171 AGPANRLAGSPPGSGQWK-PKVESGDPSLHPPPSPGTPSATP--------ASPPASATPS 221
G N+ G PP G+ + P + G+ S PPP PG P P PP P
Sbjct: 148 GG--NQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPE 205
Query: 222 QRQCVSAATSTNDSFEIRPAPKPVMETIPLGDLQARALASLRANSRNSFMVIPKSKASGA 281
S P P+P P S N P K G
Sbjct: 206 GPPPQGGNQSQG------PPPRPGKPEGP---------PSQGGNKPQGPPPHP-GKPQGP 249
Query: 282 PPPEGR--QSVELPKGDLGPASPSQELGSQPVPGGDGAP 318
PP EG Q P GP P QP+P G P
Sbjct: 250 PPQEGNKPQRPPPPGRPQGPPPPGGN-PQQPLPPPAGKP 287
Score = 33.1 bits (74), Expect = 0.86
Identities = 23/68 (33%), Positives = 25/68 (36%), Gaps = 17/68 (25%)
Query: 46 PPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPAP 105
P PP PG Q PP + PPA G P+ PPPPP P
Sbjct: 257 PQRPPPPGRPQ----------GPPPPGGNPQQPLPPPA-----GKPQG--PPPPPQGGRP 299
Query: 106 PRPPPAAP 113
RPP P
Sbjct: 300 HRPPQGQP 307
Score = 32.3 bits (72), Expect = 1.5
Identities = 52/208 (25%), Positives = 66/208 (31%), Gaps = 37/208 (17%)
Query: 274 PKSKASGAPPPEGRQSVELPKGDLGPASPSQELGSQPVPGGDGAPALGKSPLEVEAQWAV 333
P K G PP G QS P P P + G+Q G P P
Sbjct: 53 PPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQ----SQGPPPRPGKP--------- 99
Query: 334 EEGACPRTATALADRAIRWQRPSSPPPFLPAASEEAEP----AEGLRVPGLAKNSREYVR 389
EG P+ R +P PPP S+ P EG G ++ R
Sbjct: 100 -EGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPR 158
Query: 390 PGLPVTFIDEVDSEEAPQAAKLPYLPHPARPL------------HPARPGCVAELQPRGS 437
PG P + + Q+ P PHP +P P RPG P+G
Sbjct: 159 PGKP----EGPPPQGGNQSQGPP--PHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGG 212
Query: 438 NTFTVVPKRKPGTLQDQHFSQANREPRP 465
N P R PG + N+ P
Sbjct: 213 NQSQGPPPR-PGKPEGPPSQGGNKPQGP 239
Score = 32.3 bits (72), Expect = 1.5
Identities = 23/79 (29%), Positives = 29/79 (36%), Gaps = 22/79 (27%)
Query: 49 PPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRR----GSPERARPPP------ 98
PP PG Q PP + +R PP P+ G+P++ PPP
Sbjct: 240 PPHPGKPQ----------GPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQG 289
Query: 99 --PPPPPAPPRPPPAAPSP 115
PPP P PP P
Sbjct: 290 PPPPPQGGRPHRPPQGQPP 308
>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
Length = 1612
Score = 63.2 bits (152), Expect = 8e-10
Identities = 83/295 (28%), Positives = 106/295 (35%), Gaps = 45/295 (15%)
Query: 46 PPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPAP 105
P P P A R PP S ++ PA P + P + P PPPP P
Sbjct: 1101 PSLPIRPSRAPSRTP------GPPSAQSSPIDA--QPATPLPQKDPAQPLEPKRPPPPRP 1152
Query: 106 PRPPPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLH--RGAGARLLSN- 162
PP P+PP P P G SP R +F S V R + + G N
Sbjct: 1153 VAPP-TRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNI 1211
Query: 163 GHSAPEPRAGPANRLAG-SPPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATPS 221
G S P P+AG LAG P G +P + PP G SA + ASA
Sbjct: 1212 GRSQPSPQAG----LAGPGPAGYSTARPTI---------PPRAGVISAPQSHARASAGRL 1258
Query: 222 QRQCVSAATSTNDSFEIRPAP-KPVMETIPLGDLQARA------LASLRANSRNSFMVIP 274
+ S + T+ P P KP P L A L + A S P
Sbjct: 1259 TPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQ-P 1317
Query: 275 KSKASGAPPPEGRQSVELPKGDLGPASPSQELGSQPVPGGDG-APALGKSPLEVE 328
+ PPP R S LP E SQP +G + +SPL+++
Sbjct: 1318 NLETPPQPPPRSRSSHSLP----------SEASSQPQVKTNGISDGKRESPLKID 1362
Score = 39.7 bits (91), Expect = 0.009
Identities = 80/317 (25%), Positives = 112/317 (35%), Gaps = 56/317 (17%)
Query: 164 HSAPEPRAGPANRLAGSPPGSGQWKPKVESGD-PSLHPPPSPGTPSATPASPPASATPSQ 222
H P +G + SP S P + G PSL PS PS TP P A ++P
Sbjct: 1068 HLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRA-PSRTPGPPSAQSSPID 1126
Query: 223 RQCVSAATSTNDSFEIR----PAPKPVM-ETIPLGDLQARALASLR--ANSRNSFMVIPK 275
Q + + + + P P+PV T P + + R A +R F I
Sbjct: 1127 AQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGI-- 1184
Query: 276 SKASGAPPPEG--RQSVELPKGDLGPASPSQELGSQPVPGGDGAPALGKSPLEVEAQWAV 333
GAPP G R+ +E PK PG +G+S +A A
Sbjct: 1185 ----GAPPSPGVARREMEAPKS----------------PGTTRKDNIGRSQPSPQAGLAG 1224
Query: 334 EEGACPRTATALADRAIRWQRPSSPP--PFLPAASEEAEPAEGLRVPGLAKNSREYVRPG 391
A TA RP+ PP + A A + G P + E +
Sbjct: 1225 PGPAGYSTA-----------RPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGS 1273
Query: 392 LPVTFIDEVDSEEAPQAAKLPY--LPHPARPLHPARPGCVAELQPRGSNTFTVVPKRKPG 449
TF+ E PQAA P LP PA+ L A + G P + P
Sbjct: 1274 ---TFLPE---PLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPP 1327
Query: 450 TLQDQHF--SQANREPR 464
+ H S+A+ +P+
Sbjct: 1328 RSRSSHSLPSEASSQPQ 1344
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 62.8 bits (151), Expect = 1e-09
Identities = 71/265 (26%), Positives = 98/265 (36%), Gaps = 48/265 (18%)
Query: 78 RFDPPAAPRRRGSPERARPPPPPPPPAPPRPPPAAPSPPAAPGPRGGGASPGARRSDFLQ 137
R P RRR SP P PPP P PPP +P +P PR SP R S +Q
Sbjct: 548 RSPSPPPTRRRRSPS---PAPPPRRRRTPTPPPRRRTP--SPPPRRRSPSP-RRYSPPIQ 601
Query: 138 KTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPS 197
+ S S P R A ++P P P R++ SPP + P + PS
Sbjct: 602 RRYSPS----PPPKRRTASPPPPPKRRASPSP--PPKRRVSHSPPPKQRSSPVTKRRSPS 655
Query: 198 L--------------------------HPPPSPGTPSATPASPP----ASATPSQRQCVS 227
L P P P P + + PP AS++P +RQ S
Sbjct: 656 LSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPS 715
Query: 228 AATSTNDSFEIRPAPKPVMETIPLGDLQARALASLRANSRNSFMVIPKSKASGAPPPEGR 287
+T P PK + + R ++S R+ S + P+ A P P
Sbjct: 716 PSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGS-----PEPAAKKPPAPPSP 770
Query: 288 QSVELPKGDLGPASPSQELGSQPVP 312
+ P + PA P ++ S P P
Sbjct: 771 VQSQSPSTNWSPAVPVKKAKS-PTP 794
Score = 45.4 bits (106), Expect = 2e-04
Identities = 129/565 (22%), Positives = 176/565 (31%), Gaps = 135/565 (23%)
Query: 68 PPGRVS---RLLERFDPPAAPRRRGSPERARPPPPPPPPAPPRPPPAAP----------- 113
PP R S R R P A+P RR R RP PP PP R P
Sbjct: 374 PPKRTSSPPRKTRRLSPSASPPRR----RHRPSPPATPPPKTRHSPTPQQSNRTRKSRVS 429
Query: 114 --------------------SPPAAPGPRG----------GGASPGA------------- 130
SP AP PR GG A
Sbjct: 430 VSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQN 489
Query: 131 RRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHS-----APEPRAGPAN-------RLA 178
++S + S+S P+ H G HS +P PR R +
Sbjct: 490 QQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRS 549
Query: 179 GSPPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATPSQRQCVSAATSTNDSFEI 238
SPP + + + + P P+P TP+ PP +PS R+ S
Sbjct: 550 PSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRR-----YSPPIQRRY 604
Query: 239 RPAPKPVMETI-PLGDLQARALASLRANSRNSFMVIPKSKASGAPPPEGRQSVELPKGDL 297
P+P P T P + RA S R S PK ++S P R+S L
Sbjct: 605 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSS---PVTKRRSPSLSSKHR 661
Query: 298 GPASPSQEL--GSQPVPGGDGAPA-LGKSPLEVEAQWAVEEGACPRTATALADRAIRWQR 354
+SPS+ P P +P+ ++P + V GA QR
Sbjct: 662 KGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSP-----------QR 710
Query: 355 PSSPPPFLPAASEEAEPAEGLRVPGLAKNSREYVRPGLPVTFIDEVDSEEAPQAAKLPYL 414
SP P + E ++ A S + VR V S + +
Sbjct: 711 RQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVR---------RVSSSRSVSGS----- 756
Query: 415 PHPARPLHPARPGCVAELQPRGSNTFTVVPKRKPGTLQDQHFSQANREPRPREAEEEEAS 474
P PA PA P V P +N VP +K P P ++E
Sbjct: 757 PEPAAKKPPAPPSPVQSQSP-STNWSPAVPVKKA--------KSPTPSPSPPRNSDQEGG 807
Query: 475 CLLGPTLKKRYPTVHEIEVIGGYLALQKSCLTKAGSSRKKMKISFNDKSLQTT--FEYPS 532
G KK+ H +K K KK K + T +
Sbjct: 808 ---GKKKKKKKDKKH-----------KKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAA 853
Query: 533 ESSLEQEEEVDQQEEEEEEEEEEEE 557
++L QEE V E ++E E E E+
Sbjct: 854 TTTLAQEEPVAAPEPKKETESEAED 878
Score = 37.0 bits (84), Expect = 0.060
Identities = 82/415 (19%), Positives = 127/415 (30%), Gaps = 54/415 (13%)
Query: 82 PAAPRRRGSPERARPPPPPPPPAPPRPPPAAPSPPAAPGPRGGGASPGARRSDFLQKTGS 141
P+ + + + P P P P P P P S + S +S ++ S
Sbjct: 233 PSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRS 292
Query: 142 NSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPP 201
S T PR HR +P R P R P PP
Sbjct: 293 PSHT-RPRRRHRSRSRSYSPRRRPSPRRRPSPRRRT-----------------PPRRMPP 334
Query: 202 PSPGTPSATPASPPASATPSQRQCVSAATSTNDSFEIRPAPKPVMETIPLGDLQARALAS 261
P S +P ++ S +S ++S++ S R PK + + R L+
Sbjct: 335 PPRHRRSRSPVRRRRRSSAS----LSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSP 390
Query: 262 L----RANSRNSFMVIPKSKASGAPPPEGRQSVELPKGDLGPASPSQELGSQPVPGGDGA 317
R R S P K +P P+ + + P S ++ +
Sbjct: 391 SASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRES 450
Query: 318 PALGKSPLEVEAQWAVEE--GACPRTATALADRAIRWQRPSSPPPFLPAASEEAEPAEGL 375
P+ P +VE + E+ G + R R Q S ++S E E +
Sbjct: 451 PSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRS 510
Query: 376 RVPGLAKNSREYVRPGLPVTFIDEVDSEEAPQAAKLPYLPHP-----ARPLHPARPGCVA 430
V R P + +E + P P R PA P
Sbjct: 511 HVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPP---- 566
Query: 431 ELQPRGSNTFTVVPKRKPGTLQDQHFSQANREPRPREAEEEEASCLLGPTLKKRY 485
PR T T P+R+ + + R P PR P +++RY
Sbjct: 567 ---PRRRRTPTPPPRRRTPSPPPR-----RRSPSPRR---------YSPPIQRRY 604
Score = 31.6 bits (70), Expect = 2.5
Identities = 30/123 (24%), Positives = 48/123 (39%), Gaps = 27/123 (21%)
Query: 7 RRRGGGAAGARLLERYRRVPGVRALRADSVLIIETVPGFPPAPPAPGAAQIRAAEVLVYG 66
+RR + R + R R P + ++ A P+P + + ++ V G
Sbjct: 709 QRRQSPSPSTRPIRRVSRTPEPKKIKK-------------AASPSPQSVRRVSSSRSVSG 755
Query: 67 APPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPAPP----RPPPAAPSPPAAPGPR 122
+P + PPA P SP +++ P PA P + P +PSPP
Sbjct: 756 SPEPAAKK------PPAPP----SPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQE 805
Query: 123 GGG 125
GGG
Sbjct: 806 GGG 808
Score = 30.4 bits (67), Expect = 5.6
Identities = 22/103 (21%), Positives = 48/103 (46%), Gaps = 5/103 (4%)
Query: 524 LQTTFEYPSESSLEQEEEVDQQEEEEEEEEEEEEEEEGSGSEEKPFALFLPRATFVSSVR 583
L+ E + +EQE+ ++++E++++ ++EE+E S + + R + S R
Sbjct: 124 LELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPR 183
Query: 584 PESSRLPEGSSGLSSYTPKHSVAFSKWQEQALEQAPREAEPPP 626
SS + S +P+H + + ++ AP + E P
Sbjct: 184 RRSSPVRRERKRSHSRSPRH-----RTKSRSPSPAPEKKEKTP 221
Score = 29.6 bits (65), Expect = 9.6
Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 2/51 (3%)
Query: 197 SLHPPPSPGTPSATPASPPASATPSQRQCVSAATSTNDSFEIRPAPKPVME 247
S P P+P TP P S + V ATST+D ++ P P+P+ E
Sbjct: 207 SRSPSPAPEKKEKTPELPEPSVKVKE-PSVQEATSTSDILKV-PKPEPIPE 255
>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
Length = 1350
Score = 62.4 bits (150), Expect = 1e-09
Identities = 78/271 (28%), Positives = 96/271 (35%), Gaps = 36/271 (13%)
Query: 46 PPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPAP 105
P P P A R PP S ++ PA P + P + P PPPP P
Sbjct: 1101 PSLPIRPSRAPSRTP------GPPSAQSSPIDA--QPATPLPQKDPAQPLEPKRPPPPRP 1152
Query: 106 PRPPPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLH--RGAGARLLSN- 162
PP P+PP P P G SP R +F S V R + + G N
Sbjct: 1153 VAPP-TRPAPPQRPPPPSGARSPAPTRKEFGGIGAPPSPGVARREMEAPKSPGTTRKDNI 1211
Query: 163 GHSAPEPRAGPANRLAG-SPPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATPS 221
G S P P+AG LAG P G +P + PP G SA + ASA
Sbjct: 1212 GRSQPSPQAG----LAGPGPAGYSTARPTI---------PPRAGVISAPQSHARASAGRL 1258
Query: 222 QRQCVSAATSTNDSFEIRPAP-KPVMETIPLGDLQARA------LASLRANSRNSFMVIP 274
+ S + T+ P P KP P L A L + A S P
Sbjct: 1259 TPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQ-P 1317
Query: 275 KSKASGAPPPEGRQSVELPKGDLGPASPSQE 305
+ PPP R S LP + P QE
Sbjct: 1318 NLETPPQPPPRSRSSHSLPSE--ASSQPQQE 1346
Score = 40.0 bits (92), Expect = 0.007
Identities = 80/320 (25%), Positives = 113/320 (35%), Gaps = 56/320 (17%)
Query: 164 HSAPEPRAGPANRLAGSPPGSGQWKPKVESGD-PSLHPPPSPGTPSATPASPPASATPSQ 222
H P +G + SP S P + G PSL PS PS TP P A ++P
Sbjct: 1068 HLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRA-PSRTPGPPSAQSSPID 1126
Query: 223 RQCVSAATSTNDSFEIR----PAPKPVM-ETIPLGDLQARALASLR--ANSRNSFMVIPK 275
Q + + + + P P+PV T P + + R A +R F I
Sbjct: 1127 AQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGGI-- 1184
Query: 276 SKASGAPPPEG--RQSVELPKGDLGPASPSQELGSQPVPGGDGAPALGKSPLEVEAQWAV 333
GAPP G R+ +E PK PG +G+S +A A
Sbjct: 1185 ----GAPPSPGVARREMEAPKS----------------PGTTRKDNIGRSQPSPQAGLAG 1224
Query: 334 EEGACPRTATALADRAIRWQRPSSPP--PFLPAASEEAEPAEGLRVPGLAKNSREYVRPG 391
A TA RP+ PP + A A + G P + E +
Sbjct: 1225 PGPAGYSTA-----------RPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGS 1273
Query: 392 LPVTFIDEVDSEEAPQAAKLPY--LPHPARPLHPARPGCVAELQPRGSNTFTVVPKRKPG 449
TF+ E PQAA P LP PA+ L A + G P + P
Sbjct: 1274 ---TFLPE---PLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPP 1327
Query: 450 TLQDQHF--SQANREPRPRE 467
+ H S+A+ +P+ +
Sbjct: 1328 RSRSSHSLPSEASSQPQQEQ 1347
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 62.4 bits (150), Expect = 1e-09
Identities = 56/175 (32%), Positives = 62/175 (35%), Gaps = 28/175 (16%)
Query: 45 FPPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARPPPPPPPPA 104
F APP P A P VS L PP P P PP PPP
Sbjct: 211 FADAPPPPSA-------------PNPVVSSLGSGLPPPGMPPPGSFP----PPVPPPGAL 253
Query: 105 PPRPPPAAPSPPAAPGPRG-GGASPGARRSDFLQKTGSNSFTVHPRGL-HRGAGARLLSN 162
PP PPA P PP PG G G S G + S+ P G+ H G L++
Sbjct: 254 PPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAH 313
Query: 163 --GHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPP 215
H P AGP P GQ P+ G P PPP P P P
Sbjct: 314 HGPHGLGHPHAGP-------PGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSP 361
Score = 40.4 bits (93), Expect = 0.005
Identities = 49/190 (25%), Positives = 58/190 (30%), Gaps = 48/190 (25%)
Query: 43 PGFPPAPPAPGAAQIRAAEVLVYGA-PPGRVSRLLERFDPPAAPR--------------- 86
P PP P PGAA GA PG F P P
Sbjct: 259 PAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHG 318
Query: 87 ----RRGSPERARPPPPPPPPAPPRP-PPAAPSPPAAPGPRGGGASPGARRSDFLQKTGS 141
G P PPP PPP P P PP PP P PG
Sbjct: 319 LGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPG------------ 366
Query: 142 NSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPP 201
+ P G+ RG + +G++ P PR PP G + + P+ PP
Sbjct: 367 ---PMPPHGM-RGPPPLMPPHGYTGP-PR----------PPPYGYQRGPLPPPRPTPRPP 411
Query: 202 PSPGTPSATP 211
P P P
Sbjct: 412 VPPRGPLRGP 421
Score = 34.7 bits (78), Expect = 0.30
Identities = 31/90 (34%), Positives = 35/90 (38%), Gaps = 14/90 (15%)
Query: 43 PGFPPAPPAPGAAQIRAAEVLVYGAP---PGRVSRLLERFDPPAAPRRRGSPERARPPP- 98
PG P P P R +G+P PG + R PP P G RPPP
Sbjct: 339 PGMPHPGPPPMGMPPRGPP---FGSPMGHPGPMPPHGMRGPPPLMPPH-GYTGPPRPPPY 394
Query: 99 -----PPPPPAP-PRPPPAAPSPPAAPGPR 122
P PPP P PRPP P P P+
Sbjct: 395 GYQRGPLPPPRPTPRPPVPPRGPLRGPLPQ 424
Score = 33.1 bits (74), Expect = 0.86
Identities = 24/82 (29%), Positives = 29/82 (35%)
Query: 139 TGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSL 198
T S +F +G G+ A L + P A +PP P V S L
Sbjct: 173 TVSYAFKKDSKGERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGL 232
Query: 199 HPPPSPGTPSATPASPPASATP 220
PP P S P PP A P
Sbjct: 233 PPPGMPPPGSFPPPVPPPGALP 254
>gi|19924099 synapsin I isoform Ia [Homo sapiens]
Length = 705
Score = 62.0 bits (149), Expect = 2e-09
Identities = 89/312 (28%), Positives = 110/312 (35%), Gaps = 50/312 (16%)
Query: 83 AAPRRR---GSPERARPPPPPPPPAPP-----RPPPAAPSPPAAPGPRGGGASPG---AR 131
A PR+R SP R P P A P PA P P P+GG PG R
Sbjct: 417 ALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQR 476
Query: 132 RSDFLQKTGSNSFTVHPRGLHRGAGARL---LSNGHSAPEPRAGPANRLAGSPPGSGQWK 188
+ LQ+ H GL AG+ L L + SAP+ PA++ A G G+
Sbjct: 477 QGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQ---PASQAAPPTQGQGRQS 533
Query: 189 PKVESGDPSLHPPPSPGTPSATPASPPASATPSQRQCVSAATSTNDSFEIRPAPKPVMET 248
V G PG P A A PPAS +P QRQ +T + PAP P
Sbjct: 534 RPVAGG---------PGAPPA--ARPPASPSP-QRQ-AGPPQATRQTSVSGPAP-PKASG 579
Query: 249 IPLGDLQARALASLRANSRNSFMVIPKSKASGAPPPEGRQSVELPKGDLGPASPSQELGS 308
P G Q + P K G P + S P GP + Q S
Sbjct: 580 APPGGQQRQG---------------PPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPS 624
Query: 309 QPVPGGDGAPALGKSP-LEVEAQWAVEEGACPR---TATALADRAIRWQRPSSPPPFLPA 364
P P G P L + P +V G P + A P+ P P L
Sbjct: 625 GPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPEPAPPRPSLSQ 684
Query: 365 ASEEAEPAEGLR 376
+AE LR
Sbjct: 685 DEVKAETIRSLR 696
Score = 57.4 bits (137), Expect = 4e-08
Identities = 71/274 (25%), Positives = 98/274 (35%), Gaps = 68/274 (24%)
Query: 43 PGFPPA---------PPAPGAAQIRAAEVL-----------VYGAPPGRVSRLLERFDPP 82
P PPA PP PG R L + G P S L +R P
Sbjct: 452 PAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSP 511
Query: 83 ----------AAPRRRGSPERARPPPPPPPPAPPRPPPAAPSPPAAPG------------ 120
AAP +G ++RP P P PPA+PSP G
Sbjct: 512 TSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSG 571
Query: 121 ---PRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRL 177
P+ GA PG + Q+ G P G R A + P PR GP
Sbjct: 572 PAPPKASGAPPGGQ-----QRQGPPQKPPGPAGPTRQA-------SQAGPVPRTGPPTTQ 619
Query: 178 AGSPPGSG-QWKPKVESGDPSLHPPPSPGTPSATPASPPASATPSQRQCVSAATSTNDSF 236
P G G +PK P L PS P PA+ A P + ++ + S ++F
Sbjct: 620 QPRPSGPGPAGRPK-----PQLAQKPSQDVP--PPATAAAGGPPHPQ--LNKSQSLTNAF 670
Query: 237 EIRPAPKPVMETIPLGDLQARALASLRANSRNSF 270
+ P P P ++ +++A + SLR + + F
Sbjct: 671 NL-PEPAPPRPSLSQDEVKAETIRSLRKSFASLF 703
Score = 37.4 bits (85), Expect = 0.046
Identities = 17/36 (47%), Positives = 18/36 (50%), Gaps = 1/36 (2%)
Query: 95 RPPPPPPPPAPPRPPPAAPSPPAAPGPRGGGASPGA 130
RP PPPPPP P A P P A R G +P A
Sbjct: 27 RPQPPPPPPG-AHSPGATPGPGTATAERSSGVAPAA 61
Score = 37.4 bits (85), Expect = 0.046
Identities = 67/292 (22%), Positives = 93/292 (31%), Gaps = 74/292 (25%)
Query: 148 PRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTP 207
PR R A S+G + P P A P R P +G P+ PP G P
Sbjct: 419 PRQRQRDASPGRGSHGQT-PSPGALPLGRQTSQQP----------AGPPAQQRPPPQGGP 467
Query: 208 SATPASPPASATPSQRQCVSAATSTNDSFEIRPAPKPVMETIPLGDLQARALASLRANSR 267
P P Q+ RP P+ LG L +
Sbjct: 468 PQPGPGPQRQGPPLQQ---------------RPPPQGQQHLSGLGPPAGSPLPQRLPSPT 512
Query: 268 NSFMVIPKSKASGAPPP---EGRQSVELPKGDLGPASPSQELGSQPVPGGDGAPALGKSP 324
++ P+ AS A PP +GRQS +PV GG GAP + P
Sbjct: 513 SA----PQQPASQAAPPTQGQGRQS-------------------RPVAGGPGAPPAARPP 549
Query: 325 L-----------EVEAQWAVEEGACPRTATALADRAIRWQRPSSPPPFLPAASEEAEPAE 373
+ Q +V A P+ + A R P PP A + ++
Sbjct: 550 ASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPP---GPAGPTRQASQ 606
Query: 374 GLRVPGLAKNSREYVRP------GLPVTFIDEVDSEEAPQAAKLPY--LPHP 417
VP + + RP G P + + S++ P A PHP
Sbjct: 607 AGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHP 658
Score = 33.1 bits (74), Expect = 0.86
Identities = 20/50 (40%), Positives = 25/50 (50%), Gaps = 17/50 (34%)
Query: 92 ERARPPPPPP----PPAPPRP------------PPAAPSPPAAPGPRGGG 125
+R +PPPPPP P A P P P A+P+ P+ PG GGG
Sbjct: 26 QRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPS-PGSSGGG 74
>gi|33667117 MICAL-like 2 isoform 1 [Homo sapiens]
Length = 904
Score = 61.6 bits (148), Expect = 2e-09
Identities = 105/429 (24%), Positives = 143/429 (33%), Gaps = 56/429 (13%)
Query: 43 PGFPPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLER-FDPPAAPRRRGSPERARPPPPPP 101
P P AP A A V V SRL + PR S P
Sbjct: 295 PARASVPAAPNPAATSATSVHVRSPARPSESRLAPTPTEGKVRPRVTNSSPMGWSSAAPC 354
Query: 102 PPAP---PRPPPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGAR 158
A P PP+AP P A P+GGGA A L + +++ TV P A
Sbjct: 355 TAAAASHPAVPPSAPDPRPAT-PQGGGAPRVAAPQTTLSSSSTSAATVDPPAWTPSASRT 413
Query: 159 LLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLH------------PPPSPGT 206
+ P L+G P K S + + + P+PG
Sbjct: 414 QQARNKFFQTSAVPPGTSLSGRGPTPSLVLSKDSSKEQARNFLKQALSALEEAGAPAPGR 473
Query: 207 PSATPASPPASATPSQRQCVSAATSTNDSFEIR----------PAPKPVMETIPLGDLQA 256
PS A+ P+S ++ S S R PAP T L
Sbjct: 474 PSPATAAVPSSQPKTEAPQASPLAKPLQSSSPRVLGLPSRMEPPAPLSTSSTSQASALPP 533
Query: 257 RALASLRANSRNSFMVIPKSKASGAPPPEGRQ-------SVELPKG-DLGPA-------- 300
+L +S + AP +G+ S L +G + GPA
Sbjct: 534 AGRRNLAESSGVGRVGAGSRPKPEAPMAKGKSTTLTQDMSTSLQEGQEDGPAGWRANLKP 593
Query: 301 ----SPSQELGSQPVPGGDGAPALGKSPLEVEAQWAVEEGACPRTATALADRAIRWQRPS 356
SP++ P P G++P +V +A G+ T T + R R RP+
Sbjct: 594 VDRRSPAERTLKPKEPRALAEPRAGEAPRKVSGSFA---GSVHITLTPV--RPDRTPRPA 648
Query: 357 SPPPFLPAASEEAEPAEGLRVPGLAKNSREYVRPGLPVTFIDEVDSEEAPQAAKLPYLP- 415
SP P LPA S L VP ++RP P E + + K P+L
Sbjct: 649 SPGPSLPARSPSPPRRRRLAVPASLDVCDNWLRPEPPG---QEARVQSWKEEEKKPHLQG 705
Query: 416 HPARPLHPA 424
P RPL PA
Sbjct: 706 KPGRPLSPA 714
Score = 30.8 bits (68), Expect = 4.3
Identities = 84/403 (20%), Positives = 131/403 (32%), Gaps = 58/403 (14%)
Query: 80 DPPAAPRRRGSPERARPPPPPPPPAPPRPPPAAPSPPAAPGPRGGGASPGARRSDFLQKT 139
D P + +P +A P P P P PA +P G G P ++D
Sbjct: 124 DSEEEPSGKKAPVQAAKLPSPAPARKPPLSPAQTNPVVQRRNEGAGGPP--PKTDQALAG 181
Query: 140 GSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGD---P 196
S T G H R L++G R+ + SG +K E G
Sbjct: 182 SLVSSTCGVCGKHVHLVQRHLADGRL--YHRSCFRCKQCSCTLHSGAYKATGEPGTFVCT 239
Query: 197 SLHPPPSPGTPSAT---PASPPASATPSQRQC-----VSAATSTNDSFEIRPAPKPVMET 248
S P + +P T P P A S+ C A + ++E P +
Sbjct: 240 SHLPAAASASPKLTGLVPRQPGAMGVDSRTSCSPQKAQEANKARPSAWEPAAGNSPARAS 299
Query: 249 IPLGDLQARALAS---LRANSRNSFMVIPKSKASGAPPPEGRQSVELPKGDLGPAS---- 301
+P A A+ +R+ +R S + + G P S + P +
Sbjct: 300 VPAAPNPAATSATSVHVRSPARPSESRLAPTPTEGKVRPRVTNSSPMGWSSAAPCTAAAA 359
Query: 302 ------PSQELGSQPVPGGDGAPALGKSPLEVEAQWAVEEGACPRTATALADRA----IR 351
PS P G GAP + + + P T A R +
Sbjct: 360 SHPAVPPSAPDPRPATPQGGGAPRVAAPQTTLSSSSTSAATVDPPAWTPSASRTQQARNK 419
Query: 352 WQRPSSPPPFLPAASEEAEPAEGLRVPGLAKNSREYVR-------------PGLPVTFID 398
+ + S+ PP + P+ L + +R +++ PG P
Sbjct: 420 FFQTSAVPPGTSLSGRGPTPSLVLSKDSSKEQARNFLKQALSALEEAGAPAPGRPSPATA 479
Query: 399 EVDSE----EAPQAAKLPYLPHPARPLHPARP---GCVAELQP 434
V S EAPQA+ L A+PL + P G + ++P
Sbjct: 480 AVPSSQPKTEAPQASPL------AKPLQSSSPRVLGLPSRMEP 516
>gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens]
Length = 753
Score = 61.6 bits (148), Expect = 2e-09
Identities = 93/355 (26%), Positives = 126/355 (35%), Gaps = 62/355 (17%)
Query: 43 PGFPPAPPAPGAAQIRAAE----VLVYGAPPGRVSRLLERFDPPAAPRRRGSPER----- 93
P +P PP P A+ + V APP + PA G+P
Sbjct: 321 PTYPSGPP-PAASALSTTPGNNGVPAPAAPPSALGPKAS----PAPSHNSGTPAPYAQAV 375
Query: 94 ARPPPPPPPPAPPRPPPAAPSPPAAPGPRGGGASPGARRS---DFLQKTGSNSFT----- 145
A P P P PRPP PS G GGG+S + S ++ G+ S++
Sbjct: 376 APPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVAD 435
Query: 146 ------VHPRGLHRGAGARL--LSNGHSAP-----EPRAGPANRLAGSPPGSGQWKPKVE 192
+ G + + L S H+ P EP A G PGSG
Sbjct: 436 SPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTGAGGVAPGSGN-----N 490
Query: 193 SGDPSLHPPPSPGTPSATPASPPASATPSQRQCVSAATSTNDSFEIRPAPKPVMETIPLG 252
SG PSL P P +PP+S TPS +A N + AP+ + PL
Sbjct: 491 SGGPSLLVP--------LPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPE-IKAPEPLS 541
Query: 253 DLQARALASLRANSRNSFMVIPKSKASGAPPPEGRQSVELPKGDLGPAS--PSQELGSQP 310
L +++A A S +P + + + L PAS P +L
Sbjct: 542 SL--KSMAERAAISSGIEDPVPTLHLT-------ERDIILSSTSAPPASAQPPLQLSEVN 592
Query: 311 VPGGDGAPALGKSPLEVEA--QWAVEEGACPRTATALADRAIRWQRPSSPPPFLP 363
+P G LG PL E Q A+EE A IR P +P P P
Sbjct: 593 IPLSLGVCPLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPP 647
>gi|22027541 programmed cell death 7 [Homo sapiens]
Length = 485
Score = 61.6 bits (148), Expect = 2e-09
Identities = 65/217 (29%), Positives = 85/217 (39%), Gaps = 33/217 (15%)
Query: 81 PPAAPRRRGSPERARPPPPPP--PPAPPRPPPAAPSP-PAAPGPRGGGASPGARRSDFLQ 137
PP + R P +PPPP P P PP P PA P P P PGP G ++P FLQ
Sbjct: 4 PPFFGQGRPGPPPPQPPPPAPFGCPPPPLPSPAFPPPLPQRPGPFPGASAP------FLQ 57
Query: 138 KTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPS 197
P L A A G A P L PP + P ++G+
Sbjct: 58 P---------PLALQPRASAEASRGGGGAGAFYPVPPPPLPPPPPQCRPF-PGTDAGERP 107
Query: 198 LHPPPSPGTPSAT--PASPPASATP---------SQRQCVSAATSTNDSFEIRPAPKPVM 246
PPP PG P + P +PP A RQ + A T P P+
Sbjct: 108 RPPPPGPGPPWSPRWPEAPPPPADVLGDAALQRLRDRQWLEAVFGTPRRAGC-PVPQRTH 166
Query: 247 ETIPLGDLQARALASLR--ANSRNSFMVIPKSKASGA 281
LG+++AR L +LR R + +++A GA
Sbjct: 167 AGPSLGEVRARLLRALRLVRRLRGLSQALREAEADGA 203
Score = 44.7 bits (104), Expect = 3e-04
Identities = 44/151 (29%), Positives = 53/151 (35%), Gaps = 42/151 (27%)
Query: 43 PGFPPA-PPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERAR------ 95
P FPP P PG PG + L+ PP A + R S E +R
Sbjct: 35 PAFPPPLPQRPGPF-------------PGASAPFLQ---PPLALQPRASAEASRGGGGAG 78
Query: 96 -----PPPPPPPPAP-------------PRPPPAAPSPPAAPGPRGGGASPGARRSD-FL 136
PPPP PPP P PRPPP P PP +P P D L
Sbjct: 79 AFYPVPPPPLPPPPPQCRPFPGTDAGERPRPPPPGPGPPWSPRWPEAPPPPADVLGDAAL 138
Query: 137 QKTGSNSFTVHPRGLHRGAGARLLSNGHSAP 167
Q+ + G R AG + H+ P
Sbjct: 139 QRLRDRQWLEAVFGTPRRAGCPVPQRTHAGP 169
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 61.6 bits (148), Expect = 2e-09
Identities = 46/141 (32%), Positives = 53/141 (37%), Gaps = 16/141 (11%)
Query: 81 PPAAPRR-RGSPERARPPPPPPPPAPPRPPPAAPSPPAAPGPRGGGASPGARRSDFLQKT 139
PPA PR RG+P A PPP PAPP PP + A PR A+ A S +
Sbjct: 108 PPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQP 167
Query: 140 GSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLH 199
G + P A A AP A PA PP V + +P L
Sbjct: 168 GPRAQRAAPLAAPPPAPA--------APPAVAPPAGPRRAPPPA-------VAAREPPLP 212
Query: 200 PPPSPGTPSATPASPPASATP 220
PPP P P PP P
Sbjct: 213 PPPQPPAPPQQQQPPPPQPQP 233
Score = 60.1 bits (144), Expect = 7e-09
Identities = 97/359 (27%), Positives = 125/359 (34%), Gaps = 84/359 (23%)
Query: 48 APPAPGAAQI--RAAEVLVYGAPPGRVSRLLERFDPPAAPRRRGSPERARP----PPPPP 101
APP+PG AQ RA APP + PPA PRR P A PPPP
Sbjct: 158 APPSPGPAQPGPRAQRAAPLAAPPPAPAAP-PAVAPPAGPRRAPPPAVAAREPPLPPPPQ 216
Query: 102 PPAPP---RPPPAAPSPPAAPGP-RGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGA 157
PPAPP +PPP P PP G R GGA+ + ++ G + GAG
Sbjct: 217 PPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVRYLGGSG----------GAGG 266
Query: 158 RLL-SNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGD-PSLHPPPSPGTPSAT----- 210
RL E A RL + G+ + GD P PP + PS +
Sbjct: 267 RLTRGRVQGLLEEEAAARGRLERTRLGA----LALPRGDRPGRAPPAASARPSRSKRGGE 322
Query: 211 --------------------PASPPASATPSQRQCVSAATSTNDSFEIRPAPKPVMETIP 250
S + S R + N + A + V E P
Sbjct: 323 ERVLEKEEEEDDDEDEDEEDDVSEGSEVPESDRPAGAQHHQLNGERGPQSAKERVKEWTP 382
Query: 251 LGDLQARALA---SLRANSRNSFMVIPKSK----ASGAPPPEGRQSVELPKGDLGPASPS 303
G Q + + + +R F + +K AS A P+ V LP G PA
Sbjct: 383 CGPHQGQDEGRGPAPGSGTRQVFSMAAMNKEGGTASVATGPDSPSPVPLPPGK--PA--- 437
Query: 304 QELGSQPVPGGDGAPALGKSPLEVE-----AQWAV-------EEGACPRTATALADRAI 350
+PG DG P G P E +W V E P ATA ++ I
Sbjct: 438 -------LPGADGTP-FGCPPGRKEKPSDPVEWTVMDVVEYFTEAGFPEQATAFQEQEI 488
Score = 52.4 bits (124), Expect = 1e-06
Identities = 95/394 (24%), Positives = 139/394 (35%), Gaps = 62/394 (15%)
Query: 193 SGDPSLHPPPSPGTPSATPASPPASATPSQRQCVSAATSTNDSFEIRP------------ 240
+G P+L PP + + A+ ++A+P ++ + + S + RP
Sbjct: 2 AGPPALPPPETAAAATTAAAASSSAASPHYQEWILDTIDSLRSRKARPDLERICRMVRRR 61
Query: 241 -APKPVMETIPLGDL-QARALASLRANSRNSFMVIPKSKASGAPPPEGRQSVELPKGDLG 298
P+P L L Q RA+ LR + + S ++ A PP G P+ G
Sbjct: 62 HGPEPERTRAELEKLIQQRAV--LRVSYKGSISY--RNAARVQPPRRGATPPAPPRAPRG 117
Query: 299 PASPSQELGSQPVPGGDGAPALGKSPLEVEAQWAVEEGACPRTATALADRAIRWQR--PS 356
+ + P P PA + A A A + A R QR P
Sbjct: 118 APAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPL 177
Query: 357 SPPPFLPAASEE-AEPAEGLRVPGLAKNSREYVRPGLPVTFIDEVDSEEAPQAAKLPYLP 415
+ PP PAA A PA R P A +RE P LP P A P
Sbjct: 178 AAPPPAPAAPPAVAPPAGPRRAPPPAVAARE---PPLP--------PPPQPPAPPQQQQP 226
Query: 416 HPARPLHPARPGCVAELQPRGSNTFTVVPKRKPGTLQDQHFSQANREPRPR-EAEEEEAS 474
P +P P G V R V R+ R R R + EE +
Sbjct: 227 PPPQPQPPPEGGAV-----RAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEA 281
Query: 475 CLLGPTLKKRYPTVHEIEVIGGYLALQKSCLTKAGSSRKKMKISFNDKSLQTTFEYPSES 534
G + R G LAL + + G ++ PS S
Sbjct: 282 AARGRLERTRL----------GALALPRG--DRPG------------RAPPAASARPSRS 317
Query: 535 SLEQEEEVDQQEEEEEEEEEEEEEEEGSGSEEKP 568
EE V ++EEEE+++E+E+EE++ S E P
Sbjct: 318 KRGGEERVLEKEEEEDDDEDEDEEDDVSEGSEVP 351
Score = 38.5 bits (88), Expect = 0.021
Identities = 34/137 (24%), Positives = 51/137 (37%), Gaps = 8/137 (5%)
Query: 176 RLAGSPPGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATPSQRQCVSAATSTNDS 235
R +PP + + + PPP+P P P +P A+A P++ +AA +T
Sbjct: 103 RRGATPPAPPRAPRGAPAAAAAAAPPPTPAPP--PPPAPVAAAAPARAPRAAAAAAT--- 157
Query: 236 FEIRPAPKPVMETIPLGDLQARALASLRANSRNSFMVIPKSKASGAPPPEGRQSVELPKG 295
P+P P + P A A A + + P PP + LP
Sbjct: 158 --APPSPGPA-QPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPP 214
Query: 296 DLGPASPSQELGSQPVP 312
PA P Q+ P P
Sbjct: 215 PQPPAPPQQQQPPPPQP 231
>gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor [Homo
sapiens]
Length = 1336
Score = 61.2 bits (147), Expect = 3e-09
Identities = 71/243 (29%), Positives = 94/243 (38%), Gaps = 36/243 (14%)
Query: 90 SPERARPPPPPPPPAPPRPPPAAPSPPAAPGP-----------------RGGGASPGARR 132
S E A PP PPPP P P PA P+P APGP +G G GA
Sbjct: 898 SAEAAPPPAKPPPPPQPLPSPAYPAPRPAPGPAPFVPRERASVDRWRRTKGAGPPGGAGL 957
Query: 133 SDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVE 192
+D + + P+GL G G + +A P + PA + PP S + V
Sbjct: 958 ADGFHRYYG---PIEPQGLGLGLGEARAAPRGAAGRPLSPPAAQPPQKPPPS--YFAIVR 1012
Query: 193 SGDPSLHPPPS--PGTPSATPASPPASATPSQRQCVSAATSTNDSFEIRPAPKPVMETIP 250
+P+ PP PG PS P +PPA+A + + +FE P P P
Sbjct: 1013 DKEPA-EPPAGAFPGFPS--PPAPPAAAATAVGPPLCRL-----AFEDESPPAPA--RWP 1062
Query: 251 LGDLQARALASLRANSRNSFMVIPKSKASGAPPPEGRQSVELPKGDLGPASPSQELGSQP 310
D +++ L A A APPP P DL P SPS S+
Sbjct: 1063 RSDPESQPLLGPGAGGAGG-TGGAGGGAPAAPPPCRAAPPPCPYLDLEP-SPSDSEDSES 1120
Query: 311 VPG 313
+ G
Sbjct: 1121 LGG 1123
Score = 33.1 bits (74), Expect = 0.86
Identities = 51/209 (24%), Positives = 59/209 (28%), Gaps = 62/209 (29%)
Query: 43 PGFPPAPPAPGAAQIRAAEVLVY--------GAPPGRVSRL--LERFDPPAAPRR----- 87
P +P PAPG A E PPG R+ P P+
Sbjct: 918 PAYPAPRPAPGPAPFVPRERASVDRWRRTKGAGPPGGAGLADGFHRYYGPIEPQGLGLGL 977
Query: 88 -------RGSPERARPPPPPPPPAPPRP-------------PPAA-----PSPPAAPGPR 122
RG+ R PP PP P P PPA PSPPA P
Sbjct: 978 GEARAAPRGAAGRPLSPPAAQPPQKPPPSYFAIVRDKEPAEPPAGAFPGFPSPPAPPAAA 1037
Query: 123 GGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSPP 182
P R F ++ A AR +P GP AG
Sbjct: 1038 ATAVGPPLCRLAFEDESPP-------------APAR-WPRSDPESQPLLGPGAGGAGGTG 1083
Query: 183 GSGQWKPKVESGDPSLHPPPSPGTPSATP 211
G+G P PPP P P
Sbjct: 1084 GAGGGAPAA--------PPPCRAAPPPCP 1104
Score = 30.4 bits (67), Expect = 5.6
Identities = 35/113 (30%), Positives = 40/113 (35%), Gaps = 35/113 (30%)
Query: 43 PGFPPAPPAPGAAQIRAAEVLVYGAPPGRVSRLLERFDPPAAPRR--RGSPER------- 93
PGFP +PPAP AA A PP + RL + P AP R R PE
Sbjct: 1025 PGFP-SPPAPPAAAATAV------GPP--LCRLAFEDESPPAPARWPRSDPESQPLLGPG 1075
Query: 94 ---------------ARPPP--PPPPPAPPRPPPAAPSPPAAPGPRGGGASPG 129
A PPP PPP P +PS GG + G
Sbjct: 1076 AGGAGGTGGAGGGAPAAPPPCRAAPPPCPYLDLEPSPSDSEDSESLGGASLGG 1128
Score = 30.0 bits (66), Expect = 7.3
Identities = 33/124 (26%), Positives = 44/124 (35%), Gaps = 24/124 (19%)
Query: 97 PPPPPPPAPPRP--------PPAAPSPPAAPGPRGGGASPGARRSDFLQKTGSNSFTVHP 148
PPPPP A P P P + P P A A+P R + + + + P
Sbjct: 1209 PPPPPWAAGPLPRRRARCGCPRSHPHRPRASHRTPAAAAPHHHR----HRRAAGGWDLPP 1264
Query: 149 RGLHRGAGARLLSNGHSAPEPRAGPANRLAGSP------PGSGQWKPKVESGDPSLHPPP 202
+R L + S PRA PA RL G P + W P + + H
Sbjct: 1265 ----PAPTSRSLEDLSSC--PRAAPARRLTGPSRHARRCPHAAHWGPPLPTASHRRHRGG 1318
Query: 203 SPGT 206
GT
Sbjct: 1319 DLGT 1322
>gi|19924097 synapsin I isoform Ib [Homo sapiens]
Length = 669
Score = 60.8 bits (146), Expect = 4e-09
Identities = 88/303 (29%), Positives = 109/303 (35%), Gaps = 64/303 (21%)
Query: 83 AAPRRR---GSPERARPPPPPPPPAPP-----RPPPAAPSPPAAPGPRGGGASPG---AR 131
A PR+R SP R P P A P PA P P P+GG PG R
Sbjct: 417 ALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQR 476
Query: 132 RSDFLQKTGSNSFTVHPRGLHRGAGARL---LSNGHSAPEPRAGPANRLAGSPPGSGQWK 188
+ LQ+ H GL AG+ L L + SAP+ PA++ A G G+
Sbjct: 477 QGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQ---PASQAAPPTQGQGRQS 533
Query: 189 PKVESGDPSLHPPPSPGTPSATPASPPASATPSQRQCVSAATSTNDSFEIRPAPKPVMET 248
V G PG P A A PPAS +P QRQ +T + PAP P
Sbjct: 534 RPVAGG---------PGAPPA--ARPPASPSP-QRQ-AGPPQATRQTSVSGPAP-PKASG 579
Query: 249 IPLGDLQARALASLRANSRNSFMVIPKSKASGAPPPEGRQSVELPKGDLGPASPSQELGS 308
P G Q + P K G P + S P GP + Q S
Sbjct: 580 APPGGQQRQG---------------PPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPS 624
Query: 309 QPVPGGDGAPALGKSPLEVEAQWAVEEGACPRTATALADRAIRWQRPSSPPPFLPAASEE 368
P P G P L + P + P ATA A P P L A+ +
Sbjct: 625 GPGPAGRPKPQLAQKPSQ----------DVPPPATAAAG--------GPPHPQLKASPAQ 666
Query: 369 AEP 371
A+P
Sbjct: 667 AQP 669
Score = 54.7 bits (130), Expect = 3e-07
Identities = 62/230 (26%), Positives = 80/230 (34%), Gaps = 61/230 (26%)
Query: 43 PGFPPA---------PPAPGAAQIRAAEVL-----------VYGAPPGRVSRLLERFDPP 82
P PPA PP PG R L + G P S L +R P
Sbjct: 452 PAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSP 511
Query: 83 ----------AAPRRRGSPERARPPPPPPPPAPPRPPPAAPSPPAAPG------------ 120
AAP +G ++RP P P PPA+PSP G
Sbjct: 512 TSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSG 571
Query: 121 ---PRGGGASPGARRSDFLQKTGSNSFTVHPRGLHRGAGARLLSNGHSAPEPRAGPANRL 177
P+ GA PG + Q+ G P G R A + P PR GP
Sbjct: 572 PAPPKASGAPPGGQ-----QRQGPPQKPPGPAGPTRQA-------SQAGPVPRTGPPTTQ 619
Query: 178 AGSPPG---SGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATPSQRQ 224
P G +G+ KP++ + PS PP + P P A+P+Q Q
Sbjct: 620 QPRPSGPGPAGRPKPQL-AQKPSQDVPPPATAAAGGPPHPQLKASPAQAQ 668
Score = 40.8 bits (94), Expect = 0.004
Identities = 73/308 (23%), Positives = 98/308 (31%), Gaps = 78/308 (25%)
Query: 148 PRGLHRGAGARLLSNGHSAPEPRAGPANRLAGSPPGSGQWKPKVESGDPSLHPPPSPGTP 207
PR R A S+G + P P A P R P +G P+ PP G P
Sbjct: 419 PRQRQRDASPGRGSHGQT-PSPGALPLGRQTSQQP----------AGPPAQQRPPPQGGP 467
Query: 208 SATPASPPASATPSQRQCVSAATSTNDSFEIRPAPKPVMETIPLGDLQARALASLRANSR 267
P P Q+ RP P+ LG L +
Sbjct: 468 PQPGPGPQRQGPPLQQ---------------RPPPQGQQHLSGLGPPAGSPLPQRLPSPT 512
Query: 268 NSFMVIPKSKASGAPPP---EGRQSVELPKGDLGPASPSQELGSQPVPGGDGAPALGKSP 324
++ P+ AS A PP +GRQS +PV GG GAP + P
Sbjct: 513 SA----PQQPASQAAPPTQGQGRQS-------------------RPVAGGPGAPPAARPP 549
Query: 325 L-----------EVEAQWAVEEGACPRTATALADRAIRWQRPSSPPPFLPAASEEAEPAE 373
+ Q +V A P+ + A R P PP A + ++
Sbjct: 550 ASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPP---GPAGPTRQASQ 606
Query: 374 GLRVPGLAKNSREYVRPGLPVTFIDEVDSEEAPQAAKLPY--LPHPAR-----PLHPARP 426
VP + + RP P PQ A+ P +P PA P HP
Sbjct: 607 AGPVPRTGPPTTQQPRPSGP-----GPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLK 661
Query: 427 GCVAELQP 434
A+ QP
Sbjct: 662 ASPAQAQP 669
Score = 37.4 bits (85), Expect = 0.046
Identities = 17/36 (47%), Positives = 18/36 (50%), Gaps = 1/36 (2%)
Query: 95 RPPPPPPPPAPPRPPPAAPSPPAAPGPRGGGASPGA 130
RP PPPPPP P A P P A R G +P A
Sbjct: 27 RPQPPPPPPG-AHSPGATPGPGTATAERSSGVAPAA 61
Score = 33.1 bits (74), Expect = 0.86
Identities = 20/50 (40%), Positives = 25/50 (50%), Gaps = 17/50 (34%)
Query: 92 ERARPPPPPP----PPAPPRP------------PPAAPSPPAAPGPRGGG 125
+R +PPPPPP P A P P P A+P+ P+ PG GGG
Sbjct: 26 QRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPS-PGSSGGG 74
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.130 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,476,746
Number of Sequences: 37866
Number of extensions: 2962636
Number of successful extensions: 118971
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2036
Number of HSP's successfully gapped in prelim test: 2039
Number of HSP's that attempted gapping in prelim test: 29611
Number of HSP's gapped (non-prelim): 36946
length of query: 678
length of database: 18,247,518
effective HSP length: 109
effective length of query: 569
effective length of database: 14,120,124
effective search space: 8034350556
effective search space used: 8034350556
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.